C. Y. Chen, S. L. Liu, H. C. Yeh, H. T. Li, W. J. Li
{"title":"Secondary Metabolites of Plukenetia volubilis","authors":"C. Y. Chen, S. L. Liu, H. C. Yeh, H. T. Li, W. J. Li","doi":"10.1007/s10600-024-04508-y","DOIUrl":"10.1007/s10600-024-04508-y","url":null,"abstract":"<p>A new ketone, volubilisone A (<b>1</b>), along with seven known compounds including <i>trans</i>-methyl-<i>p</i>-coumarate (<b>2</b>), methyl-<i>p</i>-methoxybenzoate (<b>3</b>), coniferyl aldehyde (<b>4</b>), methyl ferulate (<b>5</b>), ferulic acid (<b>6</b>), <i>p</i>-coumaric acid (<b>7</b>), and protocatechuic acid (<b>8</b>), were isolated from the seed shells of <i>Plukenetia volubilis</i> L. (Euphorbiaceae). The structure of the new hexenone derivative was elucidated by chemical and physical evidence.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"60 6","pages":"1008 - 1010"},"PeriodicalIF":0.8,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142645708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. T. Chang, C. M. Liu, W. J. Li, H. T. Li, C. Y. Chen
{"title":"Secondary Metabolites of Ficus formosana","authors":"C. T. Chang, C. M. Liu, W. J. Li, H. T. Li, C. Y. Chen","doi":"10.1007/s10600-024-04537-7","DOIUrl":"10.1007/s10600-024-04537-7","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"60 6","pages":"1136 - 1138"},"PeriodicalIF":0.8,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142645414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mengshan Ji, Shuaibo He, Yuhang Zhang, Jiaqi Shi, Wenjun Wei, Tao Guo
{"title":"A New Phenylpropanoid Compound from the Bulbs of Lilium brownii","authors":"Mengshan Ji, Shuaibo He, Yuhang Zhang, Jiaqi Shi, Wenjun Wei, Tao Guo","doi":"10.1007/s10600-024-04515-z","DOIUrl":"10.1007/s10600-024-04515-z","url":null,"abstract":"<p><i>Lilium brownii</i> is a commonly used medicinal and food plant species in China. In this study, we investigated the chemical components of the ethanol extract from bulbs of <i>L</i>. <i>brownii</i>. As a result, a new compound (regaloside N, <b>1</b>) and ten known phenylpropanoid compounds (<b>2–11</b>) were isolated from the bulbs of <i>L</i>. <i>brownii</i>. The structure of the new compound was elucidated by spectroscopy, acid hydrolysis and derivatization.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"60 6","pages":"1039 - 1041"},"PeriodicalIF":0.8,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142645710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rongrui Wei, Jiazeng Guo, Wemin Liu, Huaqiang Wu, Qinge Ma
{"title":"Structural Characterization and Hepatoprotective Activities of 2-(2-Phenylethyl)Chromone Derivatives from Highland Barley Monascus purpureus","authors":"Rongrui Wei, Jiazeng Guo, Wemin Liu, Huaqiang Wu, Qinge Ma","doi":"10.1007/s10600-024-04509-x","DOIUrl":"10.1007/s10600-024-04509-x","url":null,"abstract":"<p>A novel 2-(2-phenylethyl)chromone derivative, named 6,7-dimethoxy-2-[2-(3′ ,4′ ,5′ -trimethoxyphenyl)ethyl]chromone (<b>1</b>), and eight known 2-(2-phenylethyl)chromone derivatives (<b>2–9</b>) were isolated from highland barley <i>Monascus purpureus</i> for the first time. Compounds <b>1–9</b> were determined by extensive spectroscopic data and reported references and they were evaluated for their hepatoprotective activities on L-O2 cells with Bifendatatum as the positive drug. As a result, compounds <b>1</b>, <b>4</b>, and <b>8</b> exhibited certain hepatoprotective activities.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"60 6","pages":"1011 - 1015"},"PeriodicalIF":0.8,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142645692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Secondary Metabolites of Two Desert Endophytic Fungi Neocamarosporum sp. and Alternaria sp.","authors":"Hua-Yang Pan, Hua-Guang Liu, Hui-Ying Liu, Yu Liu, Shuang-Mei Yan, Xiao-Long Zhao, Du-Qiang Luo","doi":"10.1007/s10600-024-04511-3","DOIUrl":"10.1007/s10600-024-04511-3","url":null,"abstract":"<p>Four new compounds (<b>1</b>–<b>4</b>) along with twelve known compounds (<b>5</b>–<b>16</b>) were isolated from the fermentation broth of two desert endophytic fungi Neocamarosporum sp. HM 175 and Alternaria sp. HM 213. The structures of the compounds were elucidated by ESI-MS and NMR data. The PTP1B inhibitory activity results showed that compounds <b>2</b>, <b>5</b>, <b>11</b>, <b>12</b>, and <b>13</b> exhibited certain inhibitory activity on PTP1B. The activity test of these compounds provided potential drug lead compounds for the research and development of new PTP1B inhibitors.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"60 6","pages":"1021 - 1028"},"PeriodicalIF":0.8,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142645693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Isolation and Characterization of Flavonolignan from Cucumis bisexualis and Their Hepatoprotective Activities","authors":"Qinge Ma, Wenmin Liu, Rongrui Wei","doi":"10.1007/s10600-024-04510-4","DOIUrl":"10.1007/s10600-024-04510-4","url":null,"abstract":"<p><i>Cucumis bisexualis</i> is a delicious fruit with diverse constituents and multiple bioactivities. A novel flavonolignan, named 2-(3′-methoxyphenyl)-(4′→1′′)-O-β-D-glucopyranosyl-7′′′-(4′′′-methoxyphenyl)-pyrano-chromene-4,9′′′-dione (<b>1</b>), and five known flavonolignan derivatives (<b>2–6</b>) were isolated from <i>C</i>. <i>bisexualis</i> for the first time. These compounds (<b>1–6</b>) were identified by their spectral data and reported references. The hepatoprotective activities of compounds (<b>1–6</b>) on HepG2 cells were evaluated with quercetin as positive control. As a result, compounds <b>1</b>, <b>3</b>, <b>4</b> were found to exhibit moderate hepatoprotective activity.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"60 6","pages":"1016 - 1020"},"PeriodicalIF":0.8,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142645694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chemical Constituents of Seriphidium transiliense and Their Anti-Inflammatory Activity","authors":"F. Wang, H. Wen, L. Liu, F. He, X. Xin","doi":"10.1007/s10600-024-04507-z","DOIUrl":"10.1007/s10600-024-04507-z","url":null,"abstract":"<p>Seven compounds were isolated from <i>Seriphidium transiliense</i>, of which 1–5 and 7 were obtained for the first time. Compound 1 was a new natural compound that was previously synthesized. Compounds 4, 5, and 7 in LPS-stimulated BV2 cells inhibited the NO content with IC<sub>50</sub> 42.24, 44.03, and 35.67 μM, respectively.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"60 6","pages":"1005 - 1007"},"PeriodicalIF":0.8,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142645691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}