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Phytochemical Characterization, Antibacterial, Synergistic Antibacterial and Cytotoxic Activities of the Essential Oil of Melastoma sanguineum 三色瘤挥发油的植物化学特性、抑菌、协同抑菌及细胞毒活性研究
IF 1.1 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-06-18 DOI: 10.1007/s10600-026-05022-z
Ling Gu, Qinglei Han, Pengxiang Lai
{"title":"Phytochemical Characterization, Antibacterial, Synergistic Antibacterial and Cytotoxic Activities of the Essential Oil of Melastoma sanguineum","authors":"Ling Gu, Qinglei Han, Pengxiang Lai","doi":"10.1007/s10600-026-05022-z","DOIUrl":"10.1007/s10600-026-05022-z","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 3","pages":"615 - 618"},"PeriodicalIF":1.1,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148553270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two New Antiviral Aromatic Sesquiterpenes from the Stem Bark of Cigar Tobacco 从雪茄烟草茎皮中提取的两种新型抗病毒芳香倍半萜
IF 1.1 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-06-18 DOI: 10.1007/s10600-026-04998-y
Jin Wang, Zhi-Hua Huang, Heng Yao, Gao-Kun Zhao, Yu-Long Su, Guang-Hai Zhang, Yong Xu, Yu-Ping Wu, Guang-Hui Kong, Jing Li, Wen-Bing Zhou
{"title":"Two New Antiviral Aromatic Sesquiterpenes from the Stem Bark of Cigar Tobacco","authors":"Jin Wang,&nbsp;Zhi-Hua Huang,&nbsp;Heng Yao,&nbsp;Gao-Kun Zhao,&nbsp;Yu-Long Su,&nbsp;Guang-Hai Zhang,&nbsp;Yong Xu,&nbsp;Yu-Ping Wu,&nbsp;Guang-Hui Kong,&nbsp;Jing Li,&nbsp;Wen-Bing Zhou","doi":"10.1007/s10600-026-04998-y","DOIUrl":"10.1007/s10600-026-04998-y","url":null,"abstract":"<p>Two new aromatic sesquiterpenes, 2-isopropyl-5-methyl-4-(4-methylfuran-2-yl)phenol (<b>1</b>) and 5-(hydroxymethyl)-2-isopropyl-4-(4-methylfuran-2-yl)phenol (<b>2</b>), as well as five known ones (<b>3–7</b>) were isolated from the stem bark of cigar tobacco. Their structures were determined mainly by spectroscopic methods, including extensive 1D and 2D NMR techniques. The antiviral activity of compounds <b>1</b> and <b>2</b> against tobacco mosaic virus (TMV) were detected. Interestingly, compounds <b>1</b> and <b>2</b> exhibited potential anti-TMV activities with inhibition rates with inactivation effects 30.8% and 36.4%, and a protective effect of 32.5% and 34.9%, respectively. These rates are close to that of the positive control.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 3","pages":"520 - 523"},"PeriodicalIF":1.1,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148553258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Composition of Volatile Oil and Acetylcholinesterase Inhibitory Activity from the Leaves of Macaranga pachyphylla 厚叶Macaranga叶片挥发油成分及乙酰胆碱酯酶抑制活性研究
IF 1.1 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-06-18 DOI: 10.1007/s10600-026-05023-y
Aliceson Masah, Nur Nabilah Mohd Zaini, Faezatul Alwani Mohd Rahim, Wan Mohd Nuzul Hakimi Wan Salleh, Abubakar Siddiq Salihu, Nurunajah Abd Ghani, Jesus Pala-Paul, Juan Francisco Perez-Sabino
{"title":"Composition of Volatile Oil and Acetylcholinesterase Inhibitory Activity from the Leaves of Macaranga pachyphylla","authors":"Aliceson Masah,&nbsp;Nur Nabilah Mohd Zaini,&nbsp;Faezatul Alwani Mohd Rahim,&nbsp;Wan Mohd Nuzul Hakimi Wan Salleh,&nbsp;Abubakar Siddiq Salihu,&nbsp;Nurunajah Abd Ghani,&nbsp;Jesus Pala-Paul,&nbsp;Juan Francisco Perez-Sabino","doi":"10.1007/s10600-026-05023-y","DOIUrl":"10.1007/s10600-026-05023-y","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 3","pages":"619 - 621"},"PeriodicalIF":1.1,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148553262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel Furan Derivative from Melia azedarach 苦楝的新型呋喃衍生物
IF 1.1 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-06-18 DOI: 10.1007/s10600-026-04996-0
Ping He, Yan Fu, Junhui Zhang, Shenghe Yang, Jiali Lang, Jian Su, Yibing Wu
{"title":"Novel Furan Derivative from Melia azedarach","authors":"Ping He,&nbsp;Yan Fu,&nbsp;Junhui Zhang,&nbsp;Shenghe Yang,&nbsp;Jiali Lang,&nbsp;Jian Su,&nbsp;Yibing Wu","doi":"10.1007/s10600-026-04996-0","DOIUrl":"10.1007/s10600-026-04996-0","url":null,"abstract":"<p>A novel furan derivative ethyl (<i>E</i>)-3-formyl-4-[5-(hydroxymethyl)furan-2-yl]but-3-enoate (<b>1</b>) was isolated from the fruits of <i>Melia azedarach</i> L. The structure was elucidated using various spectroscopic methods, including 1D and 2D NMR experiments.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 3","pages":"512 - 514"},"PeriodicalIF":1.1,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148553263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical Constituents of Swietenia macrophylla 大叶甜菊的化学成分
IF 1.1 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-06-18 DOI: 10.1007/s10600-026-05008-x
C. Y. Chen, M. J. Cheng, S. T. Huang, H. T. Li, W. J. Li
{"title":"Chemical Constituents of Swietenia macrophylla","authors":"C. Y. Chen,&nbsp;M. J. Cheng,&nbsp;S. T. Huang,&nbsp;H. T. Li,&nbsp;W. J. Li","doi":"10.1007/s10600-026-05008-x","DOIUrl":"10.1007/s10600-026-05008-x","url":null,"abstract":"<p>A new amide, swietamide (<b>1</b>), along with ten known compounds, including 4-hydroxy-4-methylpentan-2-one (diacetone alcohol) (<b>2</b>), 1-triacontanol (<b>3</b>), swietenine (<b>4</b>), swietenine acetate (<b>5</b>), swietenolide (<b>6</b>), methyl caffeate (<b>7</b>), syringaldehyde (<b>8</b>), 3′,4′,5′-trimethoxycinnamyl alcohol (<b>9</b>), apigenin (<b>10</b>), and kaempferol (<b>11</b>) were isolated from the seeds of <i>Swietenia macrophylla</i> (Meliaceae). The structure of the new butanamide derivative (<b>1</b>) was elucidated by physical evidence.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 3","pages":"563 - 566"},"PeriodicalIF":1.1,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148553266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A New Steroid from Neofusicoccum sp. CCT-Y4 Neofusicoccum sp. CCT-Y4的一个新甾体
IF 1.1 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-06-18 DOI: 10.1007/s10600-026-05005-0
Lian-Qiong Du, Xiao-Jun Li, Xu-Ping Zhang, Wei-Guang Wang, Qian-Qian Yin, Lu Gao
{"title":"A New Steroid from Neofusicoccum sp. CCT-Y4","authors":"Lian-Qiong Du,&nbsp;Xiao-Jun Li,&nbsp;Xu-Ping Zhang,&nbsp;Wei-Guang Wang,&nbsp;Qian-Qian Yin,&nbsp;Lu Gao","doi":"10.1007/s10600-026-05005-0","DOIUrl":"10.1007/s10600-026-05005-0","url":null,"abstract":"<p>A new steroid, neofusicoccumone A (<b>1</b>), along with 11 known compounds (<b>2–12</b>), were isolated from the ethyl acetate extract of the solid fermentation of the endophytic fungus <i>Neofusicoccum</i> sp. CCT-Y4 (Botryosphaeriaceae), which was isolated from the plant <i>Hedera nepalensis</i> K. Koch (Araliaceae). Their structures were identified by NMR spectroscopy and mass spectrometry. The antimicrobial activity showed that compound <b>5</b> demonstrated significant activity on <i>Fusarium</i> oxysporum Schltdl. (Nectriaceae)(60.3%) and <i>Alternaria alternata</i> (Fr.) Keissl. (Pleosporaceae) (64.0%).</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 3","pages":"549 - 553"},"PeriodicalIF":1.1,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148553267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A New Lignan from the Stems of Vitis thunbergii 标题葡萄茎中木脂素的一个新发现
IF 1.1 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-06-17 DOI: 10.1007/s10600-026-04982-6
Hung-Ju Tsai, Chiung-Lin Liu, Chan-Chiung Liu, Chi-I Chang
{"title":"A New Lignan from the Stems of Vitis thunbergii","authors":"Hung-Ju Tsai,&nbsp;Chiung-Lin Liu,&nbsp;Chan-Chiung Liu,&nbsp;Chi-I Chang","doi":"10.1007/s10600-026-04982-6","DOIUrl":"10.1007/s10600-026-04982-6","url":null,"abstract":"<p>A new lignan, (+)-9′-O-(E)-coumaroyl-5,5′-dimethoxylariciresinol (<b>1</b>), together with two known lignans, (+)-9′-O-(E)-feruloyl-5,5′-dimethoxylariciresinol (<b>2</b>) and syringaresinol (<b>3</b>), were isolated from the ethyl alcohol extract of stems of <i>Vitis thunbergii</i>. Their structures were established by analysis of spectroscopic data, including 1D and 2D NMR and HR-EI-MS, as well as by comparison with the spectral data of known analogs.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 3","pages":"444 - 446"},"PeriodicalIF":1.1,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148553201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two New Chromone Derivatives from the Fungus Aspergillus versicolor Isolated from Cigar Tobacco 从雪茄烟草中分离的两种新的彩色曲霉色素衍生物
IF 1.1 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-06-17 DOI: 10.1007/s10600-026-04983-5
Dan He, Si-Si Lin, Jian-Yong Cheng, Cheng Zhang, Yuan-Xian Zheng, Yong-Jun Zhang, Tao Wen, Jian-Duo Zhang, Qiu-Fen Hu, Jin Li, Hou-Fa Zhou
{"title":"Two New Chromone Derivatives from the Fungus Aspergillus versicolor Isolated from Cigar Tobacco","authors":"Dan He,&nbsp;Si-Si Lin,&nbsp;Jian-Yong Cheng,&nbsp;Cheng Zhang,&nbsp;Yuan-Xian Zheng,&nbsp;Yong-Jun Zhang,&nbsp;Tao Wen,&nbsp;Jian-Duo Zhang,&nbsp;Qiu-Fen Hu,&nbsp;Jin Li,&nbsp;Hou-Fa Zhou","doi":"10.1007/s10600-026-04983-5","DOIUrl":"10.1007/s10600-026-04983-5","url":null,"abstract":"<p>Two new chromones, 8-(hydroxymethyl)-6-isopropyl-2-methyl-4<i>H</i>-chromen-4-one (<b>1</b>) and 8-(hydroxymethyl)-6-isopropyl-5-methoxy-2-methyl-4<i>H</i>-chromen-4-one (<b>2</b>), along with five known ones (<b>3–7</b>) were isolated from the fungus <i>Aspergillus versicolor</i>, which derived from cigar tobacco. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds <b>1</b> and <b>2</b> were evaluated for antibacterial activity against <i>Pseudomonas syringae</i> (the main pathogenic sources of tobacco angular spot disease). The results revealed that compounds <b>1</b> and <b>2</b> exhibited inhibitory activity with MIC<sub>50</sub> values of 5.2 and 4.6 μg/mL, respectively. These rates are lower than that of the positive control (agricultural streptomycin, with MIC<sub>50</sub> of 2.2 μg/mL).</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 3","pages":"447 - 451"},"PeriodicalIF":1.1,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148553145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lignan Constituents from the Leaves of Viburnum cylindricum and Their Potential α-glucosidase Inhibitory Activity 白茅叶木脂素成分及其α-葡萄糖苷酶抑制活性研究
IF 1.1 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-06-17 DOI: 10.1007/s10600-026-04981-7
Yu-Fei Yang, Meng-Ya Yang, Ya-Jiao Chen, Jian-Hua Shao, Chun-Chao Zhao
{"title":"Lignan Constituents from the Leaves of Viburnum cylindricum and Their Potential α-glucosidase Inhibitory Activity","authors":"Yu-Fei Yang,&nbsp;Meng-Ya Yang,&nbsp;Ya-Jiao Chen,&nbsp;Jian-Hua Shao,&nbsp;Chun-Chao Zhao","doi":"10.1007/s10600-026-04981-7","DOIUrl":"10.1007/s10600-026-04981-7","url":null,"abstract":"<p>In our continuous effort to investigate hypoglycemic constituents from <i>Viburnum</i> plants, phytochemical research has discovered one undescribed tetrahydrofuran lignan, viburceol A (<b>1</b>), together with five known lignan constituents (<b>2–6</b>) from the leaves of <i>Viburnum cylindricum</i>. The structure of compound <b>1</b> was determined by spectroscopic analysis, including 1D and 2D NMR, and HR-ESI-MS, as well as DP4+ NMR and ECD calculations. Additionally, the α-glucosidase inhibitory activity of all the isolates was evaluated, among which compounds <b>5</b> and <b>6</b> exhibited moderate α-glucosidase inhibitory activity.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 3","pages":"441 - 443"},"PeriodicalIF":1.1,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148553146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inhibition of Antigen-Induced Degranulation by Secondary Metabolites Isolated from the Roots of Adenophora triphylla var. japonica in RBL-2H3 Cells 三叶参根次生代谢物对RBL-2H3细胞抗原诱导脱粒的抑制作用
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-05-11 DOI: 10.1007/s10600-026-04962-w
Eun-Kyung Ahn, Wonsik Jeong, Jae Yeon Lee, Chun Whan Choi, Joa Sub Oh, Seong Su Hong
{"title":"Inhibition of Antigen-Induced Degranulation by Secondary Metabolites Isolated from the Roots of Adenophora triphylla var. japonica in RBL-2H3 Cells","authors":"Eun-Kyung Ahn,&nbsp;Wonsik Jeong,&nbsp;Jae Yeon Lee,&nbsp;Chun Whan Choi,&nbsp;Joa Sub Oh,&nbsp;Seong Su Hong","doi":"10.1007/s10600-026-04962-w","DOIUrl":"10.1007/s10600-026-04962-w","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 2","pages":"378 - 382"},"PeriodicalIF":0.9,"publicationDate":"2026-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147938151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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