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Chemistry of Natural Compounds最新文献

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Synthesis of New Hybrid Compounds Containing Indole-Quinoline Moieties 含吲哚-喹啉基团杂化化合物的合成
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-25 DOI: 10.1007/s10600-026-04900-w
U. A. Kurbonov, Sh. N. Zhurakulov, V. I. Vinogradova, K. K. Turgunov, Yu. T. Mirzaeva, Z. D. Allaniyazova, B. Tashkhodzhaev, B. B. Shodmonov
{"title":"Synthesis of New Hybrid Compounds Containing Indole-Quinoline Moieties","authors":"U. A. Kurbonov,&nbsp;Sh. N. Zhurakulov,&nbsp;V. I. Vinogradova,&nbsp;K. K. Turgunov,&nbsp;Yu. T. Mirzaeva,&nbsp;Z. D. Allaniyazova,&nbsp;B. Tashkhodzhaev,&nbsp;B. B. Shodmonov","doi":"10.1007/s10600-026-04900-w","DOIUrl":"10.1007/s10600-026-04900-w","url":null,"abstract":"<p>New dimer compounds containing indole-quinoline moieties were synthesized from 2-chloro-6(7)-methyl-3-formylquinoline and tryptamine via a Pictet–Spengler reaction. Their relaxant activity was studied. The structures of the obtained compounds were confirmed using IR, mass, and NMR spectral data and X-ray crystal structure analyses.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"117 - 124"},"PeriodicalIF":0.9,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical Insights into the Volatile Oil of Beilschmiedia dictyoneura and Acetylcholinesterase Inhibitory Activity 双音花挥发油的化学性质及乙酰胆碱酯酶抑制活性研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-23 DOI: 10.1007/s10600-026-04916-2
Audrey Ashleeynus Allhin, Abubakar Siddiq Salihu, Wan Mohd Nuzul Hakimi Wan Salleh, Nurunajah Ab Ghani, Mohd Hafiz Arzmi, Betul Apaydin Yildirim
{"title":"Chemical Insights into the Volatile Oil of Beilschmiedia dictyoneura and Acetylcholinesterase Inhibitory Activity","authors":"Audrey Ashleeynus Allhin,&nbsp;Abubakar Siddiq Salihu,&nbsp;Wan Mohd Nuzul Hakimi Wan Salleh,&nbsp;Nurunajah Ab Ghani,&nbsp;Mohd Hafiz Arzmi,&nbsp;Betul Apaydin Yildirim","doi":"10.1007/s10600-026-04916-2","DOIUrl":"10.1007/s10600-026-04916-2","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"178 - 180"},"PeriodicalIF":0.9,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Essential Oil from Artemisia glanduligera and its Antimicrobial Activity 青蒿精油及其抑菌活性研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-23 DOI: 10.1007/s10600-026-04918-0
B. S. Okhundedaev, Kh. M. Bobakulov, Sh. R. Rakhimberdieva, S. Z. Nishanbaev, A. M. Nigmatullaev, S. A. Sasmakov, Sh. S. Azimova
{"title":"Essential Oil from Artemisia glanduligera and its Antimicrobial Activity","authors":"B. S. Okhundedaev,&nbsp;Kh. M. Bobakulov,&nbsp;Sh. R. Rakhimberdieva,&nbsp;S. Z. Nishanbaev,&nbsp;A. M. Nigmatullaev,&nbsp;S. A. Sasmakov,&nbsp;Sh. S. Azimova","doi":"10.1007/s10600-026-04918-0","DOIUrl":"10.1007/s10600-026-04918-0","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"184 - 186"},"PeriodicalIF":0.9,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Composition and Biological Activity of Essential Oil from Peucedanum coreanum 牡丹挥发油的组成及生物活性研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-23 DOI: 10.1007/s10600-026-04919-z
E. M. Suleimen, G. K. Mamytbekova, D. K. Nurkadyrov, R. V. Doudkin, P. G. Gorovoy, S. A. Ross
{"title":"Composition and Biological Activity of Essential Oil from Peucedanum coreanum","authors":"E. M. Suleimen,&nbsp;G. K. Mamytbekova,&nbsp;D. K. Nurkadyrov,&nbsp;R. V. Doudkin,&nbsp;P. G. Gorovoy,&nbsp;S. A. Ross","doi":"10.1007/s10600-026-04919-z","DOIUrl":"10.1007/s10600-026-04919-z","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"187 - 189"},"PeriodicalIF":0.9,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Constituent Composition and Biological Activity of Essential Oil from Tripolium pannonicum 三叶草挥发油的成分、成分及生物活性研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-23 DOI: 10.1007/s10600-026-04920-6
E. M. Suleimen, P. G. Gorovoy
{"title":"Constituent Composition and Biological Activity of Essential Oil from Tripolium pannonicum","authors":"E. M. Suleimen,&nbsp;P. G. Gorovoy","doi":"10.1007/s10600-026-04920-6","DOIUrl":"10.1007/s10600-026-04920-6","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"190 - 191"},"PeriodicalIF":0.9,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical Composition, Antioxidant and Enzyme Inhibitory Activities of Neolitsea hongiaoensis Leaf Essential Oil 新红枣叶精油的化学成分、抗氧化及酶抑制活性研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-23 DOI: 10.1007/s10600-026-04912-6
Nguyen Thi Ngan, Danh C. Vu, Tran Thi Huyen, Hieu Tran Trung, Nguyen Thi Phuong Thao, Hoang Van Trung
{"title":"Chemical Composition, Antioxidant and Enzyme Inhibitory Activities of Neolitsea hongiaoensis Leaf Essential Oil","authors":"Nguyen Thi Ngan,&nbsp;Danh C. Vu,&nbsp;Tran Thi Huyen,&nbsp;Hieu Tran Trung,&nbsp;Nguyen Thi Phuong Thao,&nbsp;Hoang Van Trung","doi":"10.1007/s10600-026-04912-6","DOIUrl":"10.1007/s10600-026-04912-6","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"166 - 168"},"PeriodicalIF":0.9,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical Constituents from Gastrodia elata with Promoting Collagen I Production and Cholinesterase Inhibitory Activities 天麻化学成分促进I型胶原生成及抑制胆碱酯酶活性研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-23 DOI: 10.1007/s10600-026-04892-7
Xiu-Yun Cha, Dong-Bao Hu, Xue Bai, Hui Yan, Yi-Fang Chen, Ying-Li Yang, Ji-Feng Luo, Jun Yang, Xiao-Yan Duan, Chang-Fei Zhang, Jing-Hua Yang, Meng-Hua Tian, Yun-Song Wang, Yue-Hu Wang
{"title":"Chemical Constituents from Gastrodia elata with Promoting Collagen I Production and Cholinesterase Inhibitory Activities","authors":"Xiu-Yun Cha,&nbsp;Dong-Bao Hu,&nbsp;Xue Bai,&nbsp;Hui Yan,&nbsp;Yi-Fang Chen,&nbsp;Ying-Li Yang,&nbsp;Ji-Feng Luo,&nbsp;Jun Yang,&nbsp;Xiao-Yan Duan,&nbsp;Chang-Fei Zhang,&nbsp;Jing-Hua Yang,&nbsp;Meng-Hua Tian,&nbsp;Yun-Song Wang,&nbsp;Yue-Hu Wang","doi":"10.1007/s10600-026-04892-7","DOIUrl":"10.1007/s10600-026-04892-7","url":null,"abstract":"<p>Gastrodia elata (Orchidaceae) is a material used for medicine, food, and cosmetics in China. Two new alkaloids, 1,7-bis(4-hydroxybenzyl)-1,7-dihydro-6<i>H</i>-purin-6-one (<b>1</b>) and 1,9-bis(4-hydroxybenzyl)-1,9-dihydro-6<i>H</i>-purin-6-one (<b>2</b>), five known alkaloids, (–)-(<i>R</i>)-4-(2-hydroxy-2-quinolin-4-ylethyl)phenol (<b>(</b>–<b>)-3</b>), (+)-(S)-4-(2-hydroxy-2-quinolin-4-ylethyl)phenol (<b>(+)-3</b>), 1-(4-hydroxyphenyl)-<i>β</i>-carboline (<b>4</b>), <i>p</i>-topolin riboside (<b>5</b>), and cannabisin F (<b>6</b>), and nine other compounds (<b>7–15</b>), were isolated from the rhizomes, peduncles, and inflorescences of <i>Gastrodia elata</i>, a waste collected after seed harvesting. The chemical structures of these new compounds were determined by MS and NMR spectroscopic data. These isolated alkaloids were evaluated for their cholinesterase inhibitory activity and collagen I secretion-promoting activity. Compound <b>2</b> inhibited acetylcholinesterase (AChE) with an IC<sub>50</sub> value of 19.8 ± 1.8 μM, whereas compound <b>4</b> exhibited an inhibitory effect on AChE with an IC<sub>50</sub> value of 24.7 ± 3.2 μM, and on butyrylcholinesterase (BuChE) with an IC<sub>50</sub> value of 0.84 ± 0.06 μM. At a concentration of 0.1 μM, compounds <b>(</b>–<b>)-3</b>, <b>(+)-3</b>, and <b>5</b> exhibited significant collagen I secretion-promoting activity in human dermal fibroblast adults (HDFa). These active compounds have potential for the development of neuroprotective drugs or antiaging cosmetics.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"78 - 86"},"PeriodicalIF":0.9,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical Composition and Antimicrobial Activity of Essential Oil from Vernonia arborea 林桐挥发油化学成分及抑菌活性研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-21 DOI: 10.1007/s10600-026-04915-3
Le D. Chac, Bui B. Thinh
{"title":"Chemical Composition and Antimicrobial Activity of Essential Oil from Vernonia arborea","authors":"Le D. Chac,&nbsp;Bui B. Thinh","doi":"10.1007/s10600-026-04915-3","DOIUrl":"10.1007/s10600-026-04915-3","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"175 - 177"},"PeriodicalIF":0.9,"publicationDate":"2026-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Semiliquidambar cathayensis Essential Oil: Chemical Composition, Antioxidant, and Enzyme Inhibition Activities 山楂精油：化学成分、抗氧化及酶抑制活性
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-21 DOI: 10.1007/s10600-026-04917-1
Ziyue Xu, Jiadong Zhu, Peizhong Gao, Xu Liu
{"title":"Semiliquidambar cathayensis Essential Oil: Chemical Composition, Antioxidant, and Enzyme Inhibition Activities","authors":"Ziyue Xu,&nbsp;Jiadong Zhu,&nbsp;Peizhong Gao,&nbsp;Xu Liu","doi":"10.1007/s10600-026-04917-1","DOIUrl":"10.1007/s10600-026-04917-1","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"181 - 183"},"PeriodicalIF":0.9,"publicationDate":"2026-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Cycloartane Glycoside from Astragalus macronyx 从黄芪中提取新的环ar烷糖苷
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-20 DOI: 10.1007/s10600-026-04899-0
T. N. Kaypnazarov, A. R. Khurramov, F. A. Kengesbaeva, Kh. M. Bobakulov, T. Kh. Naubeev, N. Sh. Ramazonov, F. Kh. Allaberdiev
{"title":"New Cycloartane Glycoside from Astragalus macronyx","authors":"T. N. Kaypnazarov,&nbsp;A. R. Khurramov,&nbsp;F. A. Kengesbaeva,&nbsp;Kh. M. Bobakulov,&nbsp;T. Kh. Naubeev,&nbsp;N. Sh. Ramazonov,&nbsp;F. Kh. Allaberdiev","doi":"10.1007/s10600-026-04899-0","DOIUrl":"10.1007/s10600-026-04899-0","url":null,"abstract":"<p>The known compounds cyclosieversioside E (<b>2</b>) and cyclounifolioside B (<b>3</b>) and the new cycloartane glycoside macronoside A (<b>1</b>) or 16-<i>O</i>-acetyl-20<i>R</i>,24<i>S</i>-epoxycycloartane-3<i>β</i>,6<i>α</i>,16<i>β</i>,25-tetraol 3-<i>O</i>-<i>β</i>-D-xylopyranoside were isolated from roots of the plant <i>Astragalus macronyx</i>. The structure of the last was proved based on chemical transformations, <sup>1</sup>H NMR and <sup>13</sup>C NMR data, and 2D spectra (HMBC, HSQC, COSY, ROESY).</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"114 - 116"},"PeriodicalIF":0.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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