A. U. Ubaydullaev, Sh. N. Zhurakulov, V. I. Vinogradova, K. K. Turgunov, D. B. Tukhtaev, B. Tashkhodzhaev
{"title":"Esterification of Quinoline Alkaloid Haplophyllidine by Aromatic Acids","authors":"A. U. Ubaydullaev, Sh. N. Zhurakulov, V. I. Vinogradova, K. K. Turgunov, D. B. Tukhtaev, B. Tashkhodzhaev","doi":"10.1007/s10600-026-04898-1","DOIUrl":"10.1007/s10600-026-04898-1","url":null,"abstract":"<p>New haplophyllidine derivatives were produced by esterification of the C-7 OH group with aromatic acids containing a halogen or nitro group (-F, -Cl, -Br, -I, -NO<sub>2</sub>). The structures of the obtained compounds were established using IR and NMR spectral data and X-ray crystal structure analyses (XSAs). The chiral centers retained 7R and 8R configurations in the reaction products according to XSA data.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"108 - 113"},"PeriodicalIF":0.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Simple Regiospecific Syntheses of Barleriaquinone, A Metabolite of Barleria buxifolia, and Its Structural Isomer, A Metabolite of Cinchona ledgeriana","authors":"V. L. Novikov, N. N. Balaneva, O. P. Shestak","doi":"10.1007/s10600-026-04903-7","DOIUrl":"10.1007/s10600-026-04903-7","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"136 - 138"},"PeriodicalIF":0.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Song-Yi Ji, Ling Zhang, Yong Xu, Jin Wang, Ying-Liang Zhao, Jian-Duo Zhang, Guang-Yu Yang, Qiu-Fen Hu, Jing Li, Rong Zhang
{"title":"Two New Antibacterial Pyrroloquinolines from the Tobacco Endophytic Aspergillus sp.","authors":"Song-Yi Ji, Ling Zhang, Yong Xu, Jin Wang, Ying-Liang Zhao, Jian-Duo Zhang, Guang-Yu Yang, Qiu-Fen Hu, Jing Li, Rong Zhang","doi":"10.1007/s10600-026-04895-4","DOIUrl":"10.1007/s10600-026-04895-4","url":null,"abstract":"<p>To explore more antibacterial natural products, an extract from fermentation products of tobacco endophytic <i>Aspergillus</i> sp. (YATS-225) was investigated. As a result, five pyrroloquinolines (<b>1–5</b>) were isolated. Among them, two newly discovered pyrrolo[1,2-<i>a</i>]quinolin (<b>1</b> and <b>2</b>) were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds <b>1</b> and <b>2</b> exhibited obvious antibacterial activity with a bacteriostatic diam in the range of 16.4–23.5 mm against five pathogenic strains (<i>Staphylococcus aureus, Escherichia coli, Streptococcus pneumoniae, Bacillus subtilis</i>, and <i>Proteus</i> spp.). Compounds <b>3–5</b> also exhibited potential antibacterial activity with a bacteriostatic diam in the range of 12.8–19.2 mm. In addition, compounds <b>1</b> and <b>2</b> also have potential value for use as antiseptic agents for cigarette tipping paper.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"97 - 101"},"PeriodicalIF":0.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sh. M. Adizov, O. Blacque, B. Spingler, B. Tashkhodzhaev
{"title":"Structure of a New Indole Alkaloid from Vinca erecta and Alkyl Derivatives of 12-Hydroxynorfluorocurarine","authors":"Sh. M. Adizov, O. Blacque, B. Spingler, B. Tashkhodzhaev","doi":"10.1007/s10600-026-04897-2","DOIUrl":"10.1007/s10600-026-04897-2","url":null,"abstract":"<p>The new indole alkaloid 12-hydroxydehydrotubifoline (<b>1</b>) containing the polycyclic akuammicine framework was isolated from <i>Vinca erecta</i>. Alkylation products of the major alkaloid 12-hydroxynorfluorocurarine with various alkyl halides were obtained. The structures of the new alkaloid 12-hydroxydehydrotubifoline and alkyl derivatives of 12-hydroxynorfluorocurarine were established by X-ray crystal structure analyses. Physicochemical and UV, IR, and NMR spectroscopic data of the obtained new compound were reported.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"102 - 107"},"PeriodicalIF":0.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhiwei Zhang, Jing Liu, Hongzhe Zhang, Yang Du, Xixiang Ying
{"title":"A Novel Alkaloid from Portulaca oleracea and Its Anti-Inflammatory Bioactivities","authors":"Zhiwei Zhang, Jing Liu, Hongzhe Zhang, Yang Du, Xixiang Ying","doi":"10.1007/s10600-026-04894-5","DOIUrl":"10.1007/s10600-026-04894-5","url":null,"abstract":"<p>A novel alkaloid, 2,3-dioxo-1,4-diazabicyclo[3.2.0]heptane-4-carboxylic acid, named oleraciamide I was isolated from <i>Portulaca oleracea</i> L. The structure of the compound was identified by spectroscopic methods, including 1D, 2D NMR, and UHPLC-ESI-Q-TOF/MS. It was found that oleraciamide I could significantly inhibit the production of inflammatory factor IL-1<i>β</i> at 20 μM.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"93 - 96"},"PeriodicalIF":0.9,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. M. Ikromova, S. Kh. Mullabaeva, D. R. Siddikov, E. Kh. Botirov, A. M. Karimov, K. K. Turgunov, S. A. Sasmakov, B. Tashkhodzhaev, A. M. Nigmatullaev
{"title":"Constituent Composition of Roots of Perovskia kudrjaschevii","authors":"G. M. Ikromova, S. Kh. Mullabaeva, D. R. Siddikov, E. Kh. Botirov, A. M. Karimov, K. K. Turgunov, S. A. Sasmakov, B. Tashkhodzhaev, A. M. Nigmatullaev","doi":"10.1007/s10600-026-04922-4","DOIUrl":"10.1007/s10600-026-04922-4","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"195 - 199"},"PeriodicalIF":0.9,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. H. Lee, S. T. Huang, C. F. Huang, H. K. Tsai, C. Y. Chen
{"title":"Secondary Metabolites of Ficus formosana with Antioxidant Activity","authors":"P. H. Lee, S. T. Huang, C. F. Huang, H. K. Tsai, C. Y. Chen","doi":"10.1007/s10600-026-04904-6","DOIUrl":"10.1007/s10600-026-04904-6","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"139 - 142"},"PeriodicalIF":0.9,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}