{"title":"Synthesis, Antiurease and Antioxidant Study of Two Novel Derivatives of Oleanolic Acid","authors":"Nuzhat Arshad, Sadia Ansari, Anjum Ayub, Shumaila Jawaid, Jamshed Hashim, Maaz Bin Khalid, Zarish Alamgir","doi":"10.1007/s10600-026-05079-w","DOIUrl":"10.1007/s10600-026-05079-w","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 4","pages":"840 - 842"},"PeriodicalIF":1.1,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148962309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Isolation and Structural Characterization of Chemical Constituents from the Roots of Moringa oleifera","authors":"Yuya Ota, Tetsuya Saito, Yuria Kurosu, Takahiro Hosoya","doi":"10.1007/s10600-026-05083-0","DOIUrl":"10.1007/s10600-026-05083-0","url":null,"abstract":"<p>In this study, 14 compounds, including a novel pyrrole alkaloid glycoside (<b>6</b>), were isolated from <i>Moringa oleifera</i> roots, and their structures were determined using spectroscopic analyses. This is to our knowledge the first report of compounds <b>1</b>–<b>5</b>, <b>7</b>, and <b>10</b> isolated from <i>M. oleifera</i> roots, and compounds <b>8</b>, <b>9</b>, and <b>11</b>–<b>14</b> from the plant. Our findings highlight the chemical diversity of <i>M. oleifera</i> and provide novel insights into its chemical profile.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 4","pages":"772 - 777"},"PeriodicalIF":1.1,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148962195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Sh. Akhmedova, A. A. Ganiev, Kh. M. Bobakulov, S. Z. Nishanbaev, D. A. Narbutaeva, N. D. Abdullaev, K. K. Turgunov
{"title":"New Flavone Glycoside from the Aerial Part of Datisca cannabina and Its Antiradical Activity","authors":"D. Sh. Akhmedova, A. A. Ganiev, Kh. M. Bobakulov, S. Z. Nishanbaev, D. A. Narbutaeva, N. D. Abdullaev, K. K. Turgunov","doi":"10.1007/s10600-026-05042-9","DOIUrl":"10.1007/s10600-026-05042-9","url":null,"abstract":"<p>The new flavone glycoside datiscetinoside (datiscetin-2′-O-β-D-glucopyranoside) (<b>1</b>) and ten known aglycon and glycosylated flavonoids (<b>2</b>–<b>11</b>) were isolated from the aerial part of <i>Datisca cannabina</i> (Datiscaceae). The chemical structures of the isolated compounds were proved and identified using IR, UV, <sup>1</sup>H and <sup>13</sup>C NMR spectra and COSY, HSQC, and HMBC experiments. The antiradical activity of total flavonoids obtained from the EtOAc fraction of the aqueous EtOH extract of the aerial part of <i>D. cannabina</i> was investigated.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 4","pages":"677 - 681"},"PeriodicalIF":1.1,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148962305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. H. Lee, M. J. Cheng, C. L. Kao, C. E. Kuo, S. T. Huang, H. T. Li, C. Y. Chen
{"title":"Secondary Metabolites of Hibiscus sabdariffa","authors":"P. H. Lee, M. J. Cheng, C. L. Kao, C. E. Kuo, S. T. Huang, H. T. Li, C. Y. Chen","doi":"10.1007/s10600-026-05064-3","DOIUrl":"10.1007/s10600-026-05064-3","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 4","pages":"792 - 795"},"PeriodicalIF":1.1,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148962137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. E. Chang, M. J. Cheng, C. L. Kao, S. T. Huang, C. Y. Chen, H. T. Li
{"title":"A New Apocarotenoid Glucoside of Synsepalum dulcificum","authors":"K. E. Chang, M. J. Cheng, C. L. Kao, S. T. Huang, C. Y. Chen, H. T. Li","doi":"10.1007/s10600-026-05046-5","DOIUrl":"10.1007/s10600-026-05046-5","url":null,"abstract":"<p>A new apocarotenoid glucoside, syndulcific acid (<b>1</b>) as well as (+)-vomifoliol (<b>2</b>), (+)-dehydrovomifoliol (<b>3</b>), 4-acetonyl-3,5-dimethoxy-p-quinol (<b>4</b>), protocatechuic alcohol (<b>5</b>), protocatechuic acid (<b>6</b>), malic acid (<b>7</b>), and 3-hydroxypropionic acid (<b>8</b>), were isolated from the fruits of <i>Synsepalum dulcificum</i> (Sapotaceae). The structure of the new apocarotenoid glucoside was elucidated by chemical and physical evidence.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 4","pages":"693 - 696"},"PeriodicalIF":1.1,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148962133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. A. Abdullajanov, A. A. Ganiev, N. B. Begmatov, Kh. M. Bobakulov, G. Mamajanov, J. Zhao, F. He, Sh. V. Abdullaev, I. Askarov, Kh. Bozorov, A. Turak
{"title":"Phenolic Compounds from Artemisia porrecta","authors":"O. A. Abdullajanov, A. A. Ganiev, N. B. Begmatov, Kh. M. Bobakulov, G. Mamajanov, J. Zhao, F. He, Sh. V. Abdullaev, I. Askarov, Kh. Bozorov, A. Turak","doi":"10.1007/s10600-026-05071-4","DOIUrl":"10.1007/s10600-026-05071-4","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 4","pages":"814 - 816"},"PeriodicalIF":1.1,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148962135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. H. Lee, M. J. Cheng, C. L. Kao, C. E. Kuo, S. T. Huang, H. T. Li, C. Y. Chen
{"title":"Secondary Metabolites of Castanea mollissima","authors":"P. H. Lee, M. J. Cheng, C. L. Kao, C. E. Kuo, S. T. Huang, H. T. Li, C. Y. Chen","doi":"10.1007/s10600-026-05066-1","DOIUrl":"10.1007/s10600-026-05066-1","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 4","pages":"799 - 802"},"PeriodicalIF":1.1,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148962138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Zhou, C. Liu, Z. Li, Y. Yuan, J. Zhao, H. A. Aisa
{"title":"Chemical Constituents of Cydonia oblonga and Their Anti-Inflammatory Activity","authors":"Y. Zhou, C. Liu, Z. Li, Y. Yuan, J. Zhao, H. A. Aisa","doi":"10.1007/s10600-026-05069-y","DOIUrl":"10.1007/s10600-026-05069-y","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 4","pages":"808 - 810"},"PeriodicalIF":1.1,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yu. V. Kharitonov, V. I. Antipova, M. K. Marenina, Yu. V. Meshkova, T. G. Tolstikova, E. E. Shults
{"title":"Synthetic Transformations of Higher Terpenoids. 48. Synthesis and Cytotoxic Properties of 18-Nor-Labdatriene-Containing Ureas","authors":"Yu. V. Kharitonov, V. I. Antipova, M. K. Marenina, Yu. V. Meshkova, T. G. Tolstikova, E. E. Shults","doi":"10.1007/s10600-026-05055-4","DOIUrl":"10.1007/s10600-026-05055-4","url":null,"abstract":"<p>A series of 4-ureido-18-nor-15,16-epoxy-8(17),13,14-labdatrienes were synthesized by the reaction of 4-isocyanato-18-nor-lambertianic acid with ammonia, primary and secondary amines, amino acids, and phenylamines. The reactions occurred under mild conditions with high yields of the target products. The cytotoxicity of the synthesized compounds was assessed against cultivated human tumor cells MCF-7 and HEK293T and fibroblasts hTERT-BJ1 (MTT assay). Hierarchical clustering was used for qualitative analysis of the structure–cytotoxicity relationship and revealed several patterns for the effect of the substituent nature on the cytotoxicity and selectivity. The highest selectivity against tumor cells (SI = 2.2–2.3) was found for <b>3</b>, <b>5e</b>, and <b>11b</b>.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 4","pages":"736 - 746"},"PeriodicalIF":1.1,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}