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A New Cyclic Peptide from Betel Nut Endophytic Fungus Alternaria sp. RW-AL 来自槟榔内生真菌 Alternaria sp.
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04413-4
Wu Ruan, Qing-Yun Ma, Jiao-Cen Guo, Qing-Yi Xie, Li Yang, Hao-Fu Dai, You-Geng Wu, You-Xing Zhao
{"title":"A New Cyclic Peptide from Betel Nut Endophytic Fungus Alternaria sp. RW-AL","authors":"Wu Ruan, Qing-Yun Ma, Jiao-Cen Guo, Qing-Yi Xie, Li Yang, Hao-Fu Dai, You-Geng Wu, You-Xing Zhao","doi":"10.1007/s10600-024-04413-4","DOIUrl":"https://doi.org/10.1007/s10600-024-04413-4","url":null,"abstract":"<p>A new cyclic peptide alternarin A (<b>1</b>), along with seven known compounds, alternariol (<b>2</b>), sulfated derivative of alternariol (<b>3</b>), alternariol methyl ether (<b>4</b>), altenuene (<b>5</b>), 2,5-dimethyl-7-hydroxychromone (<b>6</b>), diaporthein A (<b>7</b>), isopterocarpolone (<b>8</b>), were isolated from the betel nut endophytic fungus <i>Alternaria</i> sp. RW-AL. The structure of <b>1</b> was elucidated by 1D and 2D NMR spectra as well as HR-ESI-MS analysis. Compounds <b>1</b>, <b>4</b>, and <b>5</b> showed definite antibacterial activities against <i>Staphylococcus aureus</i> ATCC 6538 and <i>Bacillus subtilis</i> ATCC 6633.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phenylpropanoids with Anti-Inflammatory Effects from the Roots of Platycodon grandiflorus 桔梗根中具有抗炎作用的苯丙酸类化合物
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04402-7
Yang Yu, Lan Ding, Ren-Nai Yang, Liang-Ping Zha, Ju-Tao Wang, Shuang-Ying Gui
{"title":"Phenylpropanoids with Anti-Inflammatory Effects from the Roots of Platycodon grandiflorus","authors":"Yang Yu, Lan Ding, Ren-Nai Yang, Liang-Ping Zha, Ju-Tao Wang, Shuang-Ying Gui","doi":"10.1007/s10600-024-04402-7","DOIUrl":"https://doi.org/10.1007/s10600-024-04402-7","url":null,"abstract":"<p>Two new phenylpropanoids, plagnans (<b>1</b>) and plaganoid (<b>2</b>), along with five known phenylpropanoids, including an enantiomeric mixture (compound <b>3</b>) were isolated from the roots of <i>Platycodon grandiflorus.</i> Meanwhile, their structures were elucidated by analyzing the spectroscopic data, including NMR, HR-ESI-MS, ECD (ICD), and X-ray analysis. Although all isolates were evaluated for their anti-inflammatory activities, and of them exhibited moderate activities, with IC<sub>50</sub> values of around 27.5 μM.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Convenient Synthesis of Bis-(Dihydro)Caffeoylspermine 双（二氢）咖啡酰精胺的便捷合成
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04409-0
Lijuan Zhai, Jian Sun, Pengjuan Zhou, Jingwen Ji, Lili He, Dong Tang, Jinbo Ji, Haikang Yang, Zafar Iqbal, Zhixiang Yang
{"title":"Convenient Synthesis of Bis-(Dihydro)Caffeoylspermine","authors":"Lijuan Zhai, Jian Sun, Pengjuan Zhou, Jingwen Ji, Lili He, Dong Tang, Jinbo Ji, Haikang Yang, Zafar Iqbal, Zhixiang Yang","doi":"10.1007/s10600-024-04409-0","DOIUrl":"https://doi.org/10.1007/s10600-024-04409-0","url":null,"abstract":"<p>Kukoamine A has been known for decades as an anti-inflammatory and hypotensive principle of Chinese medicinal plant extract from <i>Lycium</i> root, bark, and fruit. The recent pharmacological significance of this alkaloid makes it a potential therapeutic target for the pharmaceutical industry. We accomplished the synthesis of kukoamine A in a 73% yield over four steps starting from cheaper commercial reagents, ambient reaction conditions, and minimal purification efforts.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolites from Michelia compressa var. lanyuensis with Antioxidant Activity 具有抗氧化活性的扁柏变种代谢物
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04418-z
C. T. Chang, W. J. Li, H. T. Li, S. L. Liu, C. Y. Chen
{"title":"Metabolites from Michelia compressa var. lanyuensis with Antioxidant Activity","authors":"C. T. Chang, W. J. Li, H. T. Li, S. L. Liu, C. Y. Chen","doi":"10.1007/s10600-024-04418-z","DOIUrl":"https://doi.org/10.1007/s10600-024-04418-z","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preparative Synthesis of 4-Oxooctanoic and 4-Oxodecanoic Acids - Components of Sex Pheromone of Asian Hornet Vespa velutina 亚洲大黄蜂性信息素成分--4-氧代辛酸和 4-氧代癸酸的制备合成
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04416-1
V. A. Vydrina, M. P. Yakovleva, A. A. Podsolikhina, N. M. Ishmuratova
{"title":"Preparative Synthesis of 4-Oxooctanoic and 4-Oxodecanoic Acids - Components of Sex Pheromone of Asian Hornet Vespa velutina","authors":"V. A. Vydrina, M. P. Yakovleva, A. A. Podsolikhina, N. M. Ishmuratova","doi":"10.1007/s10600-024-04416-1","DOIUrl":"https://doi.org/10.1007/s10600-024-04416-1","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis of New A-Seco-Derivatives of Methyl Glycyrrhetinate 甘草酸甲酯新 A-癸基衍生物的合成
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04407-2
E. R. Karimova, L. A. Baltina, T. R. Nugumanov, N. I. Medvedeva, L. V. Spirikhin, O. S. Kukovinets
{"title":"Synthesis of New A-Seco-Derivatives of Methyl Glycyrrhetinate","authors":"E. R. Karimova, L. A. Baltina, T. R. Nugumanov, N. I. Medvedeva, L. V. Spirikhin, O. S. Kukovinets","doi":"10.1007/s10600-024-04407-2","DOIUrl":"https://doi.org/10.1007/s10600-024-04407-2","url":null,"abstract":"<p>New A-seco-derivatives of methyl glycyrrhetinate (MeGLC) were synthesized. Cleavage of ring A of the 2-hydroxymethylene-3-oxo-derivative of MeGLC by H<sub>2</sub>O<sub>2</sub> (30%) in the presence of NaOMe (28%) in MeOH led to the 2,3-seco-2,3-diacid, which was isolated as the dimethyl ester. Ozonolysis of the 2-hydroxymethylene-3-oxo-derivative of MeGLC produced for the first time the methyl esters of 2,3-seco-2-ethoxycarbonyl- 18<i>βH</i>-olean-12-ene-2,3,30-trioic acid and 2,3-anhydro-11-oxo-18<i>βH</i>-olean-9,12-diene-2,3,30-trioic acid.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolites from the Endophytic Fungus Aspergillus niger Isolated from Clausena anisum-olens and Their Cytotoxicity 黑曲霉的代谢产物及其细胞毒性
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04421-4
Jie-ying Peng, Jia-xin Song, Li Ge, Jian-hua Yan
{"title":"Metabolites from the Endophytic Fungus Aspergillus niger Isolated from Clausena anisum-olens and Their Cytotoxicity","authors":"Jie-ying Peng, Jia-xin Song, Li Ge, Jian-hua Yan","doi":"10.1007/s10600-024-04421-4","DOIUrl":"https://doi.org/10.1007/s10600-024-04421-4","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A New Oleanane-Type Triterpene Glycoside from Nephelium lappaceum 一种新的齐墩果类三萜苷
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04406-3
Thuy Thi Xuan Vi, Hung Duc Nguyen, Tan Quang Tu, Thu Thi Mai Lo, Mau Hoang Chu
{"title":"A New Oleanane-Type Triterpene Glycoside from Nephelium lappaceum","authors":"Thuy Thi Xuan Vi, Hung Duc Nguyen, Tan Quang Tu, Thu Thi Mai Lo, Mau Hoang Chu","doi":"10.1007/s10600-024-04406-3","DOIUrl":"https://doi.org/10.1007/s10600-024-04406-3","url":null,"abstract":"<p>A new oleanane-type triterpene glycoside, 3-<i>O-α</i>-L-arabinopyranosyl-(1→3)-<i>α</i>-L-rhamnopyranosyl-(1→2)-<i>α</i>-L-arabinopyranosyloleanolic acid 28-<i>O-β</i>-D-xylopyranosyl-(1→3)-<i>β</i>-D-xylopyranosyl-(1→2)-<i>β</i>-D-glucopyranosyl ester, was isolated from the aqueous-ethanolic extract of the seeds of <i>Nephelium lappaceum</i> L. The structure elucidation of this compound was based on analyses of spectroscopic data, including 1D and 2D NMR and HR-ESI-MS techniques, and by comparing their NMR data with those reported in the literature.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolites from Alpinia officinarum with Antioxidant Activity 具有抗氧化活性的山银花代谢物
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-06 DOI: 10.1007/s10600-024-04415-2
Huei-Lin Whung, Der-An Tsao, Shih-Yi Lin, Shang-Tao Chien, Chung-Yi Chen, Chiao-Tang Chang
{"title":"Metabolites from Alpinia officinarum with Antioxidant Activity","authors":"Huei-Lin Whung, Der-An Tsao, Shih-Yi Lin, Shang-Tao Chien, Chung-Yi Chen, Chiao-Tang Chang","doi":"10.1007/s10600-024-04415-2","DOIUrl":"https://doi.org/10.1007/s10600-024-04415-2","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Triterpenes and Steroids from the Rhizomes of Hedychium glabrum 来自姬松茸根茎的三萜类和甾类化合物
IF 0.8 4区 化学
Chemistry of Natural Compounds Pub Date : 2024-08-05 DOI: 10.1007/s10600-024-04447-8
Ri-hai Zhou, Xiao-yang Zhang, Gui-ping Li, De-mei Yang, Jin-feng Zhang, Li Zheng, Wei Peng, Ye-gao Chen
{"title":"Triterpenes and Steroids from the Rhizomes of Hedychium glabrum","authors":"Ri-hai Zhou, Xiao-yang Zhang, Gui-ping Li, De-mei Yang, Jin-feng Zhang, Li Zheng, Wei Peng, Ye-gao Chen","doi":"10.1007/s10600-024-04447-8","DOIUrl":"https://doi.org/10.1007/s10600-024-04447-8","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141933505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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