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Chemistry of Natural Compounds最新文献

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Comprehensive Analysis of Bioactive Peptides from Cuminum cyminum Seeds: Sequence Identification and Pharmacological Evaluation Cuminum cyminum种子生物活性肽的综合分析：序列鉴定和药理评价
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-19 DOI: 10.1007/s10600-026-04901-9
I. Ermatov, S. Subuer, N. Ullah, H. Taurtaihon, A. Wali, Y. Mijiti
{"title":"Comprehensive Analysis of Bioactive Peptides from Cuminum cyminum Seeds: Sequence Identification and Pharmacological Evaluation","authors":"I. Ermatov,&nbsp;S. Subuer,&nbsp;N. Ullah,&nbsp;H. Taurtaihon,&nbsp;A. Wali,&nbsp;Y. Mijiti","doi":"10.1007/s10600-026-04901-9","DOIUrl":"10.1007/s10600-026-04901-9","url":null,"abstract":"<p>This study reports the first systematic isolation and characterization of bioactive peptides from <i>Cuminum cyminum</i> L. seeds using 50% ethanol extraction coupled with C18 reverse-phase chromatography. Three peptide fractions were evaluated for antimicrobial, antioxidant, and hypoglycemic activities. ZD-30 and ZD-50 exhibited potent antibacterial effects against <i>Escherichia coli</i> and significant antioxidant capacity, while ZD-70 demonstrated hypoglycemic potential via PTP1B inhibition. MALDI-TOF/TOF MS/MS analysis identified 479 unique peptide sequences, with 15 multifunctional candidates prioritized through computational tools (PeptideRanker, ToxinPred, PEP-FOLD3). Molecular dynamics simulations revealed α-helix/β-sheet conformations critical for membrane interactions and bioactivity. These findings validate <i>Cumin’s</i> traditional medicinal applications and provide a molecular foundation for developing plant-derived therapeutics targeting antimicrobial resistance and metabolic disorders.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"125 - 132"},"PeriodicalIF":0.9,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibacterial Triterpenoids and Steroids from the Endophytic Fungus Trichoderma hirsutum 内生真菌毛发木霉的抗菌三萜和甾体
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-19 DOI: 10.1007/s10600-026-04921-5
Hui Bo, Li-Juan Zhang, Xiao-Ning Liu, Li-Yan Li, Sen Pang
{"title":"Antibacterial Triterpenoids and Steroids from the Endophytic Fungus Trichoderma hirsutum","authors":"Hui Bo,&nbsp;Li-Juan Zhang,&nbsp;Xiao-Ning Liu,&nbsp;Li-Yan Li,&nbsp;Sen Pang","doi":"10.1007/s10600-026-04921-5","DOIUrl":"10.1007/s10600-026-04921-5","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"192 - 194"},"PeriodicalIF":0.9,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical Constituents of Lycium ruthenicum 枸杞化学成分研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-19 DOI: 10.1007/s10600-026-04893-6
Y. J. Tseng, T. H. Cheng, X. Y. Ji, L. C. Tsai, C. L. Kao, S. T. Huang, H. T. Li, C. Y. Chen
{"title":"Chemical Constituents of Lycium ruthenicum","authors":"Y. J. Tseng,&nbsp;T. H. Cheng,&nbsp;X. Y. Ji,&nbsp;L. C. Tsai,&nbsp;C. L. Kao,&nbsp;S. T. Huang,&nbsp;H. T. Li,&nbsp;C. Y. Chen","doi":"10.1007/s10600-026-04893-6","DOIUrl":"10.1007/s10600-026-04893-6","url":null,"abstract":"<p>A new pyridine, 2-(4′-hydroxyphenyl)-1-(4′′-hydroxypyridin-2′′′-yl)ethyl hydrogen carbonate (<b>1</b>) and eleven known compounds (<b>2–12</b>) were isolated from the fruit of <i>Lycium ruthenicum</i>. The structure of the new pyridine was elucidated by chemical and physical evidence.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"87 - 89"},"PeriodicalIF":0.9,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-Lung Cancer Activity Compounds of Crithmum maritimum 海棠抗肺癌活性化合物的研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-19 DOI: 10.1007/s10600-026-04905-5
C. Y. Chen, D. A. Tsao, C. W. Li, R. W. Huang, J. T. Shen
{"title":"Anti-Lung Cancer Activity Compounds of Crithmum maritimum","authors":"C. Y. Chen,&nbsp;D. A. Tsao,&nbsp;C. W. Li,&nbsp;R. W. Huang,&nbsp;J. T. Shen","doi":"10.1007/s10600-026-04905-5","DOIUrl":"10.1007/s10600-026-04905-5","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"143 - 146"},"PeriodicalIF":0.9,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical Constituents of Illicium tsaii 柴胡的化学成分
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-18 DOI: 10.1007/s10600-026-04909-1
Chun-Tong Li, Tian-Yi Xia, Ze-Yu Zheng, Meng-Li Chen, Zhi-Jun Wu
{"title":"Chemical Constituents of Illicium tsaii","authors":"Chun-Tong Li,&nbsp;Tian-Yi Xia,&nbsp;Ze-Yu Zheng,&nbsp;Meng-Li Chen,&nbsp;Zhi-Jun Wu","doi":"10.1007/s10600-026-04909-1","DOIUrl":"10.1007/s10600-026-04909-1","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"157 - 159"},"PeriodicalIF":0.9,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical Constituents of Perovskia scrophulariifolia 玄参钙的化学成分
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-18 DOI: 10.1007/s10600-026-04911-7
S. I. Atkiyaeva, B. S. Okhundedaev, E. Kh. Botirov, S. A. Sasmakov, Sh. S. Azimova
{"title":"Chemical Constituents of Perovskia scrophulariifolia","authors":"S. I. Atkiyaeva,&nbsp;B. S. Okhundedaev,&nbsp;E. Kh. Botirov,&nbsp;S. A. Sasmakov,&nbsp;Sh. S. Azimova","doi":"10.1007/s10600-026-04911-7","DOIUrl":"10.1007/s10600-026-04911-7","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"163 - 165"},"PeriodicalIF":0.9,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical Composition and Anti-Inflammatory Properties of Essential Oils from Peperomia dindygulensis Leaves 紫荆叶精油的化学成分及抗炎特性研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-18 DOI: 10.1007/s10600-026-04907-3
Thang Quoc Le, Bao Chi Nguyen, Duc Viet Ho, Hung Quoc Vo, Thi Minh Hoang Duong, Anh Tuan Le, Ty Viet Pham
{"title":"Chemical Composition and Anti-Inflammatory Properties of Essential Oils from Peperomia dindygulensis Leaves","authors":"Thang Quoc Le,&nbsp;Bao Chi Nguyen,&nbsp;Duc Viet Ho,&nbsp;Hung Quoc Vo,&nbsp;Thi Minh Hoang Duong,&nbsp;Anh Tuan Le,&nbsp;Ty Viet Pham","doi":"10.1007/s10600-026-04907-3","DOIUrl":"10.1007/s10600-026-04907-3","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"150 - 152"},"PeriodicalIF":0.9,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Derivatives of Salicylic Acid as Potential Antimicrobial Drugs 水杨酸作为潜在抗菌药物的新衍生物
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-18 DOI: 10.1007/s10600-026-04910-8
N. V. Groza, T. A. Yarkova, V. A. Filipovich, A. V. Rozumiy, N. N. Gessler
{"title":"New Derivatives of Salicylic Acid as Potential Antimicrobial Drugs","authors":"N. V. Groza,&nbsp;T. A. Yarkova,&nbsp;V. A. Filipovich,&nbsp;A. V. Rozumiy,&nbsp;N. N. Gessler","doi":"10.1007/s10600-026-04910-8","DOIUrl":"10.1007/s10600-026-04910-8","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"160 - 162"},"PeriodicalIF":0.9,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis of 2,4-Dienoates Based on Triphenylphosphine-Induced Rearrangement of 2,3-Allenoates Prepared from Fatty Acids 基于三苯基膦诱导2,3-烯丙酸酯重排的脂肪酸合成2,4-二烯酸酯
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-18 DOI: 10.1007/s10600-026-04902-8
G. M. Gindullina, I. M. Sakhautdinov
{"title":"Synthesis of 2,4-Dienoates Based on Triphenylphosphine-Induced Rearrangement of 2,3-Allenoates Prepared from Fatty Acids","authors":"G. M. Gindullina,&nbsp;I. M. Sakhautdinov","doi":"10.1007/s10600-026-04902-8","DOIUrl":"10.1007/s10600-026-04902-8","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"133 - 135"},"PeriodicalIF":0.9,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical Constituents from Merremia tuberosa and Their Antioxidant Activity 晚霞化学成分及其抗氧化活性研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2026-02-18 DOI: 10.1007/s10600-026-04906-4
Hsiao-Ling Huang, Su-Ting Huang, Chin-Fei Huang, Chung-Yi Chen
{"title":"Chemical Constituents from Merremia tuberosa and Their Antioxidant Activity","authors":"Hsiao-Ling Huang,&nbsp;Su-Ting Huang,&nbsp;Chin-Fei Huang,&nbsp;Chung-Yi Chen","doi":"10.1007/s10600-026-04906-4","DOIUrl":"10.1007/s10600-026-04906-4","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"62 1","pages":"147 - 149"},"PeriodicalIF":0.9,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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