发布求助
文献互助 智能选刊 最新文献

Chemistry of Natural Compounds最新文献

筛选
英文 中文
Synthesis and Cytotoxicity of New 1,2,3-Triazole Derivatives of Abietic Acid 新型枞酸1,2,3-三唑衍生物的合成及细胞毒性研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04788-y
Yong Wang, Wei Wang, Li-Na Liu, Dong-Lin Wei, Cong-Jun Liu, Shang-Hua Wei, Song Gao, Shu-Ping Yu, Ning Yao, Yu-Fei Wang
{"title":"Synthesis and Cytotoxicity of New 1,2,3-Triazole Derivatives of Abietic Acid","authors":"Yong Wang,&nbsp;Wei Wang,&nbsp;Li-Na Liu,&nbsp;Dong-Lin Wei,&nbsp;Cong-Jun Liu,&nbsp;Shang-Hua Wei,&nbsp;Song Gao,&nbsp;Shu-Ping Yu,&nbsp;Ning Yao,&nbsp;Yu-Fei Wang","doi":"10.1007/s10600-025-04788-y","DOIUrl":"10.1007/s10600-025-04788-y","url":null,"abstract":"<p>A series of abietic acid derivatives modified with a triazole moiety at the C-18 position were synthesized using Huisgen 1,3-dipolar cycloaddition reaction of 18-azidoabietane with alkynes. The antitumor activity of the synthesized compounds was investigated through human cervical cancer cells (HeLa), human breast cancer cells (MCF-7) and human renal epithelial cells (HEK-293T). The outcome indicated that compounds <b>5e</b>, <b>5f</b>, <b>5j</b> exhibited positive inhibitory activity against the tested tumor cell lines. In particular, the IC<sub>50</sub> value for the inhibitory activity of compound <b>5e</b> against human breast cancer cells (MCF-7) was 11.2 μmol/L.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"924 - 931"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Flavonoids from the Roots of Torenia concolor 花楸根中的类黄酮
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04796-y
T. L. Yang, C. L. Kao, C. E. Kuo, S. T. Huang, H. T. Li, M. J. Cheng, W. J. Li, C. Y. Chen
{"title":"Flavonoids from the Roots of Torenia concolor","authors":"T. L. Yang,&nbsp;C. L. Kao,&nbsp;C. E. Kuo,&nbsp;S. T. Huang,&nbsp;H. T. Li,&nbsp;M. J. Cheng,&nbsp;W. J. Li,&nbsp;C. Y. Chen","doi":"10.1007/s10600-025-04796-y","DOIUrl":"10.1007/s10600-025-04796-y","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"961 - 964"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acylation of Flavone O-Glycosides from Two Anthriscus Species 两种炭疽菌黄酮o -糖苷的酰化
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04785-1
D. N. Olennikov, A. N. Kazanchyan, A. A. Shamilov
{"title":"Acylation of Flavone O-Glycosides from Two Anthriscus Species","authors":"D. N. Olennikov,&nbsp;A. N. Kazanchyan,&nbsp;A. A. Shamilov","doi":"10.1007/s10600-025-04785-1","DOIUrl":"10.1007/s10600-025-04785-1","url":null,"abstract":"<p>Studies of two <i>Anthriscus</i> (Apiaceae) species, <i>A. sylvestris</i> (L.) Hoffm. and <i>A. nemorosa</i> Spreng. [syn. <i>A. sylvestris</i> subsp. <i>nemorosa</i> (M. Bieb.) C. Y. Wu &amp; F. T. Pu] led to the isolation of 11 compounds, including three new flavonoids <b>1–3</b>. The structures of the new compounds were established as apigenin 7-(2′′-<i>O</i>-caffeyl-6′′-<i>O</i>-p-coumaroyl)-<i>O</i>-<i>β</i>-D-glucopyranoside (anthriscoside A, <b>1</b>), apigenin 7-(4′′-<i>O</i>-caffeyl-6′′-O-p-coumaroyl)-<i>O</i>-<i>β</i>-D-glucopyranoside (anthriscoside B, <b>2</b>), and luteolin 7-(2′′,6′′-di-<i>O</i>-malonyl)-<i>O</i>-<i>β</i>-D-glucopyranoside (anthriscoside C, <b>3</b>). Compounds <b>1–3</b> possessed antiradical activity.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"911 - 915"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolomics of Trichoderma spirale by Mass Spectrometry Data Dereplication 螺旋木霉代谢组学的质谱分析
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04780-6
Mariana de Arruda Silva, Leticia Pereira Feijo da Silva, Arielly Celestino Rodrigues dos Santos, Ana Carolina Magalhaes Rocha, Edna Maria dos Anjos Almudi, Barbara Sayuri Bellete, Marcos Antonio Soares, Karen de Jesus Nicacio, Lucas Campos Curcino Vieira, Olivia Moreira Sampaio
{"title":"Metabolomics of Trichoderma spirale by Mass Spectrometry Data Dereplication","authors":"Mariana de Arruda Silva,&nbsp;Leticia Pereira Feijo da Silva,&nbsp;Arielly Celestino Rodrigues dos Santos,&nbsp;Ana Carolina Magalhaes Rocha,&nbsp;Edna Maria dos Anjos Almudi,&nbsp;Barbara Sayuri Bellete,&nbsp;Marcos Antonio Soares,&nbsp;Karen de Jesus Nicacio,&nbsp;Lucas Campos Curcino Vieira,&nbsp;Olivia Moreira Sampaio","doi":"10.1007/s10600-025-04780-6","DOIUrl":"10.1007/s10600-025-04780-6","url":null,"abstract":"<p><i>Trichoderma spirale</i> is an endophytic fungus with diverse biological activities, including bioherbicidal effects through photosynthesis inhibition in weeds. This study investigated the metabolome of <i>T. spirale</i> using mass spectrometry data dereplication via a molecular networking approach. The metabolites identified include isolongifolol, curcumol, L-leucyl-L-proline lactam, azelaic acid, and 2-hydroxyisocaproic acid. Thus, this work represents a significant contribution to the study of the <i>T. spirale</i> metabolome, revealing for the first time the presence of 27 metabolites in this species, including eight previously known metabolites of the <i>Trichoderma</i> genus.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"881 - 887"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antioxidant Activity in vitro of 2-Antipyrine-, (5-Thioxo-2,5-Dihydro-1H-1,2,4-Triazol)-6-YL-, (1,3,4-Thiadiazol-2-YL)-6-Carboxamide-, 6-Thioureide-, and 6-Hydrazinothiol Derivatives of Maleopimarimide 马来酰亚胺的2-安替吡林-、（5-硫氧-2,5-二氢- 1h -1,2,4-三唑）-6- yl -、（1,3,4-噻二唑-2- yl）-6-羧基酰胺-、6-硫脲-和6-肼基硫醇衍生物的体外抗氧化活性
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04790-4
G. F. Vafina, T. A. Sapozhnikova, S. F. Gabdrakhmanova
{"title":"Antioxidant Activity in vitro of 2-Antipyrine-, (5-Thioxo-2,5-Dihydro-1H-1,2,4-Triazol)-6-YL-, (1,3,4-Thiadiazol-2-YL)-6-Carboxamide-, 6-Thioureide-, and 6-Hydrazinothiol Derivatives of Maleopimarimide","authors":"G. F. Vafina,&nbsp;T. A. Sapozhnikova,&nbsp;S. F. Gabdrakhmanova","doi":"10.1007/s10600-025-04790-4","DOIUrl":"10.1007/s10600-025-04790-4","url":null,"abstract":"<p>New derivatives of maleopimaric acid containing phenylthioureide fragments were synthesized. The antioxidant activity of 24 maleopimaric acid derivatives in the 2- and 6-positions was studied in three in vitro models, i.e., FRAP, reduction of DPPH radical, and reduction of ABTS radical. Methyl-, 2-isonicotinoyl-, and 2-(pyridin-3-ylcarbonyl)hydrazinocarbonothioyl derivatives of 2-allylmaleopimarimide showed antioxidant activity in vitro in the ABTS model comparable to the reference drug ascorbic acid and superior than that of Trolox.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"936 - 940"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and Cytotoxicity of 4-Hydroxy-15-Triazolyl-Substituted Isoalantolactone Derivatives 4-羟基-15-三唑基取代异丙酸内酯衍生物的合成及细胞毒性研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04781-5
S. S. Patrushev, T. V. Rybalova, Yu. V. Meshkova, M. K. Marenina, T. G. Tolstikova, E. E. Shults
{"title":"Synthesis and Cytotoxicity of 4-Hydroxy-15-Triazolyl-Substituted Isoalantolactone Derivatives","authors":"S. S. Patrushev,&nbsp;T. V. Rybalova,&nbsp;Yu. V. Meshkova,&nbsp;M. K. Marenina,&nbsp;T. G. Tolstikova,&nbsp;E. E. Shults","doi":"10.1007/s10600-025-04781-5","DOIUrl":"10.1007/s10600-025-04781-5","url":null,"abstract":"<p>A method for modifying ring A of isoalantolactone to produce 4(<i>R</i>)-hydroxy-15-triazolyl derivatives was developed. The key steps in the transformation included sequential azidolysis of 13-methoxy-4,15-epoxy- 11,13-dihydroisoalantolactones and Cu-catalyzed azide-alkyne cycloaddition with various alkynes. A <i>retro</i>-Michael reaction of (11<i>R</i>)- and (11<i>S</i>)-stereoisomeric (4<i>R</i>)-hydroxy-13-methoxy-15-triazolyl-11,13- dihydroisoalantolactones using cesium carbonate in DMF formed isoalantolactone derivatives. The structures of three compounds were established by X-ray crystal structure analyses.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"888 - 899"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical Constituents and Antioxidant Activities from the Tender Leaves of Lycium barbarum 枸杞嫩叶化学成分及抗氧化活性研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04798-w
Tian-Yin Chen, Han Mei, Dan-Min Zhang, Chuan-Mao Zhang, Dong-Ping Li, Xin Yao, Li Zhang, Jin-Feng Cao, Jian-Hai Ding
{"title":"Chemical Constituents and Antioxidant Activities from the Tender Leaves of Lycium barbarum","authors":"Tian-Yin Chen,&nbsp;Han Mei,&nbsp;Dan-Min Zhang,&nbsp;Chuan-Mao Zhang,&nbsp;Dong-Ping Li,&nbsp;Xin Yao,&nbsp;Li Zhang,&nbsp;Jin-Feng Cao,&nbsp;Jian-Hai Ding","doi":"10.1007/s10600-025-04798-w","DOIUrl":"10.1007/s10600-025-04798-w","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"968 - 970"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis of N-Arylsulfonyl Anabasines n -芳基磺酰基苦楝碱的合成
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04795-z
M. I. Olimova, A. R. Khurramov, S. A. Sasmakov, Kh. M. Bobakulov, M. G. Levkovich, Sh. S. Azimova, B. Zh. Elmuradov
{"title":"Synthesis of N-Arylsulfonyl Anabasines","authors":"M. I. Olimova,&nbsp;A. R. Khurramov,&nbsp;S. A. Sasmakov,&nbsp;Kh. M. Bobakulov,&nbsp;M. G. Levkovich,&nbsp;Sh. S. Azimova,&nbsp;B. Zh. Elmuradov","doi":"10.1007/s10600-025-04795-z","DOIUrl":"10.1007/s10600-025-04795-z","url":null,"abstract":"<p>Reactions of the alkaloid anabasine with benzene-, <i>p</i>-toluene-, <i>o</i>-methoxyphenyl-, 3,4-dimethylbenzene-, 2,4,6-trimethylbenzene-, and <i>m</i>-nitrophenylsulfonyl chlorides under relatively mild conditions afforded the corresponding <i>N</i>-arylsulfonyl anabasines in good yields. Results of <i>in vitro</i> antimicrobial tests showed that the compounds did not exhibit antibacterial effects against microorganism strains.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"957 - 960"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HR-LC-MS Analysis of Extract from the Plant Oxytropis macrodonta 大齿棘豆提取物的HR-LC-MS分析
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04799-9
M. A. Agzamova, U. M. Omanova, G. Ozek, T. Ozek
{"title":"HR-LC-MS Analysis of Extract from the Plant Oxytropis macrodonta","authors":"M. A. Agzamova,&nbsp;U. M. Omanova,&nbsp;G. Ozek,&nbsp;T. Ozek","doi":"10.1007/s10600-025-04799-9","DOIUrl":"10.1007/s10600-025-04799-9","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"971 - 973"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytochemical Study of Artemisia porrecta 茯苓的植物化学研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04800-5
O. A. Abdullajanov, A. A. Ganiev, A. Turak, N. B. Begmatov, Kh. M. Bobakulov, J. Zhao, F. He, H. A. Aisa
{"title":"Phytochemical Study of Artemisia porrecta","authors":"O. A. Abdullajanov,&nbsp;A. A. Ganiev,&nbsp;A. Turak,&nbsp;N. B. Begmatov,&nbsp;Kh. M. Bobakulov,&nbsp;J. Zhao,&nbsp;F. He,&nbsp;H. A. Aisa","doi":"10.1007/s10600-025-04800-5","DOIUrl":"10.1007/s10600-025-04800-5","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"974 - 976"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信