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A New Diamine of Mahonia fortunei 一种新的Mahonia fortunei
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04793-1
T. L. Yang, S. L. Liu, S. T. Huang, M. J. Cheng, H. T. Li, C. Y. Chen, W. J. Li
{"title":"A New Diamine of Mahonia fortunei","authors":"T. L. Yang,&nbsp;S. L. Liu,&nbsp;S. T. Huang,&nbsp;M. J. Cheng,&nbsp;H. T. Li,&nbsp;C. Y. Chen,&nbsp;W. J. Li","doi":"10.1007/s10600-025-04793-1","DOIUrl":"10.1007/s10600-025-04793-1","url":null,"abstract":"<p>A new diamine, mahodiamine (<b>1</b>), along with 11 compounds, including scopoletin (<b>2</b>), isoscopoletin (<b>3</b>), aesculetin dimethyl ester (<b>4</b>), <i>p</i>-methoxylbenzoic acid (<b>5</b>), protocatechuic acid (<b>6</b>), ferulic acid (<b>7</b>), (+)-vomifoliol (<b>8</b>), (+)-dehydrovomifoliol (<b>9</b>), (Z)-4-hydroxy-3,5,5-trimethyl-4-(3′-oxobut-1′-enyl)cyclohex-2-enone (<b>10</b>), bis(2-ethylhexyl) terephthalate (<b>11</b>), and dibutyl phthalate (<b>12</b>), were isolated from the leaves of <i>Mahonia fortunei</i> (Lindl.) Fedde (Berberidaceae). The structure of the new diamine was elucidated by chemical and physical evidence.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"950 - 952"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the Impact of C3-Methyl of Naphtho[1,2-b]Furan-4,5-Dione Analogs for Anticancer Activity 研究c3 -甲基萘[1,2-b]呋喃-4,5-二酮类似物对抗癌活性的影响
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04782-4
Yue Zhu, Jia Yu, Xin Tan, Ni Zhang, Jin-Yu Li, Hua-Yong Lou, Heng Luo, Chao Chen, Wei-Dong Pan
{"title":"Investigating the Impact of C3-Methyl of Naphtho[1,2-b]Furan-4,5-Dione Analogs for Anticancer Activity","authors":"Yue Zhu,&nbsp;Jia Yu,&nbsp;Xin Tan,&nbsp;Ni Zhang,&nbsp;Jin-Yu Li,&nbsp;Hua-Yong Lou,&nbsp;Heng Luo,&nbsp;Chao Chen,&nbsp;Wei-Dong Pan","doi":"10.1007/s10600-025-04782-4","DOIUrl":"10.1007/s10600-025-04782-4","url":null,"abstract":"<p>To investigate the impact of C3-methyl substitution of naphtho[1,2-<i>b</i>]furan-4,5-dione analogs on antitumor efficacy, 16 NQO1 substrate analogs of C3-methylated (<b>TC1–TC8</b>) and C3-demethylated (<b>TC1</b>′<b>–TC8</b>′) were synthesized. The anticancer activities against K562, LNCaP, HeLa, and MDA-MB-231 suggested that methyl and demethyl derivatives of naphtho[1,2-<i>b</i>]furan-4,5-dione analogs have comparable cytotoxicity and this value depends more on the nature of the substituent at position C-2.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"900 - 904"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A New Tetraazacyclododecane of Ilex latifolia 标题冬青中一个新的四氮杂环十二烷
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04792-2
C. T. Chang, C. L. Kao, S. T. Huang, M. J. Cheng, C. Y. Chen, H. T. Li
{"title":"A New Tetraazacyclododecane of Ilex latifolia","authors":"C. T. Chang,&nbsp;C. L. Kao,&nbsp;S. T. Huang,&nbsp;M. J. Cheng,&nbsp;C. Y. Chen,&nbsp;H. T. Li","doi":"10.1007/s10600-025-04792-2","DOIUrl":"10.1007/s10600-025-04792-2","url":null,"abstract":"<p>A new tetraazacyclododecane, 2-nonyl-1,4,7,10-tetraazacyclododecane (<b>1</b>), along with nine isoquinoline alkaloids, northalifoline (<b>2</b>), thalifoline (<b>3</b>), corydaldine (<b>4</b>), N-methylcorydaldine (<b>5</b>), oxyberberine (<b>6</b>), berberine (<b>7</b>), palmatine (<b>8</b>), jatrorrhizine (<b>9</b>), and columbamine (<b>10</b>) were isolated from the bark of <i>Ilex latifolia</i> (Aquifoliaceae). The structure of the new tetraazacyclododecane was elucidated by chemical and physical evidence.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"947 - 949"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of Volatile Components from Alstonia rostrata 石竹中挥发性成分的鉴定
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04810-3
Aliceson Masah, Abubakar Siddiq Salihu, Wan Mohd Nuzul Hakimi Wan Salleh, Nurunajah Ab Ghani, Andrea Mastinu
{"title":"Identification of Volatile Components from Alstonia rostrata","authors":"Aliceson Masah,&nbsp;Abubakar Siddiq Salihu,&nbsp;Wan Mohd Nuzul Hakimi Wan Salleh,&nbsp;Nurunajah Ab Ghani,&nbsp;Andrea Mastinu","doi":"10.1007/s10600-025-04810-3","DOIUrl":"10.1007/s10600-025-04810-3","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"1007 - 1008"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Secondary Metabolites of Lycium chinense with Antioxidant Activity 具有抗氧化活性的枸杞次生代谢物研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04801-4
Y. J. Tseng, C. L. Kao, S. T. Huang, M. J. Cheng, W. J. Li, H. T. Li, C. Y. Chen
{"title":"Secondary Metabolites of Lycium chinense with Antioxidant Activity","authors":"Y. J. Tseng,&nbsp;C. L. Kao,&nbsp;S. T. Huang,&nbsp;M. J. Cheng,&nbsp;W. J. Li,&nbsp;H. T. Li,&nbsp;C. Y. Chen","doi":"10.1007/s10600-025-04801-4","DOIUrl":"10.1007/s10600-025-04801-4","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"977 - 980"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Secondary Metabolites of Haworthia cooperi var. truncata 龙舌兰的次生代谢物
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-18 DOI: 10.1007/s10600-025-04783-3
K. E. Chang, S. T. Huang, C. L. Kao, M. J. Cheng, C. Y. Chen, H. T. Li
{"title":"Secondary Metabolites of Haworthia cooperi var. truncata","authors":"K. E. Chang,&nbsp;S. T. Huang,&nbsp;C. L. Kao,&nbsp;M. J. Cheng,&nbsp;C. Y. Chen,&nbsp;H. T. Li","doi":"10.1007/s10600-025-04783-3","DOIUrl":"10.1007/s10600-025-04783-3","url":null,"abstract":"<p>A new chromone, 5-hydroxy-2-methoxy-6,7,8-trimethylchromone (<b>1</b>), along with ten known compounds including 5,7-dimethoxychromone (<b>2</b>), 5-hydroxy-7-methoxychromone (<b>3</b>), 5-hydroxychromone (<b>4</b>), 5,7-dihydroxy-2,6-dimethylchromone (<b>5</b>), 5,7-dihydroxy-2,8-dimethyl-chromone (<b>6</b>), 5,7-dihydroxy-2,6,8- trimethylchromone (<b>7</b>), (3<i>S</i>,4<i>R</i>)-4-hydroxymellein (<b>8</b>), (3<i>S</i>,4<i>S</i>)-4-hydroxymellein (<b>9</b>), 4-hydroxymethyl-3,5-dimethyldihydro-2-furanone (<b>10</b>), and 3,4-dihydroxy-3-methyldihydro-2-furanone (<b>11</b>), were isolated from the roots of <i>Haworthia cooperi</i> var. <i>truncata</i> (Asphodelaceae). The structure of the new chromone derivative was elucidated by chemical and physical evidence.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"905 - 907"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and Transformations of A-Seco-Triterpenoids a - seco -三萜的合成与转化
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-17 DOI: 10.1007/s10600-025-04777-1
N. V. Galaiko, V. V. Grishko
{"title":"Synthesis and Transformations of A-Seco-Triterpenoids","authors":"N. V. Galaiko,&nbsp;V. V. Grishko","doi":"10.1007/s10600-025-04777-1","DOIUrl":"10.1007/s10600-025-04777-1","url":null,"abstract":"<p>Progress during the period 2016–2024 on the synthesis and transformations of A-seco-triterpene derivatives is reviewed and analyzed. Information on their pharmacological potential is given.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"841 - 865"},"PeriodicalIF":0.9,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Novel Glycoside Compound and Antibacterial Constituents of the Fruits of Aronia melanocarpa 黑桫椤果实中一种新的苷类化合物及其抗菌成分研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-17 DOI: 10.1007/s10600-025-04786-0
Jin Hui Ma, Hong Lin Zhang, En Ji Cui, Chang Ji Zheng
{"title":"A Novel Glycoside Compound and Antibacterial Constituents of the Fruits of Aronia melanocarpa","authors":"Jin Hui Ma,&nbsp;Hong Lin Zhang,&nbsp;En Ji Cui,&nbsp;Chang Ji Zheng","doi":"10.1007/s10600-025-04786-0","DOIUrl":"10.1007/s10600-025-04786-0","url":null,"abstract":"<p>A novel glycoside compound, 3-hydroxy-5-(<i>β</i>-D-glucopyranosyloxy)-hexanoic acid (<b>1</b>) has been isolated from the fruits of <i>Aronia melanocarpa</i> (Michx.) Britton, along with ten known compounds, vanillic acid 4-<i>O</i>-<i>β</i>-D-glucoside (<b>2</b>), (<i>R</i>)-4-<i>O-β</i>-D-glucopyranoyl-4-hydroxy-2-pentanone (<b>3</b>), (6<i>R</i>,9<i>R</i>)-roseoside (<b>4</b>), phloroacetophenone 2-<i>O</i>-glucoside (<b>5</b>), methyl (3<i>S,</i>5<i>S</i>)-5-hydroxy-3-(<i>β</i>-D-glucopyranosyloxy)hexanoate (<b>6</b>), <i>β</i>-D-glucopyranosyl benzoate (<b>7</b>), parasorboside (<b>8</b>), benzyl 6-<i>O-α</i>-L-arabinofuranosyl-<i>β</i>-D-glucoside (<b>9</b>), dihydrophasmaric acid 4′-<i>O-β</i>-D-glucopyranoside (<b>10</b>), and 4-<i>O-β</i>-D-glucopyranosyl-<i>cis-p</i>-coumaric acid (<b>11</b>). The structure of compound <b>1</b> was determined by NMR spectroscopic and MS analyses. Compounds <b>1–4</b> showed antibacterial activity against <i>Staphylococcus aureus</i> RN (4220).</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"916 - 920"},"PeriodicalIF":0.9,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polysaccharides from Scutellaria. II. Structure and Properties of Polysaccharides from Scutellaria comosa 黄芩多糖。2。黄芩多糖的结构与性质
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-09-17 DOI: 10.1007/s10600-025-04778-0
R. K. Rakhmanberdyeva, A. A. Siddikova, Kh.M. Bobakulov, T. A. Petrova, M. Kh. Malikova, A. A. Ismailova
{"title":"Polysaccharides from Scutellaria. II. Structure and Properties of Polysaccharides from Scutellaria comosa","authors":"R. K. Rakhmanberdyeva,&nbsp;A. A. Siddikova,&nbsp;Kh.M. Bobakulov,&nbsp;T. A. Petrova,&nbsp;M. Kh. Malikova,&nbsp;A. A. Ismailova","doi":"10.1007/s10600-025-04778-0","DOIUrl":"10.1007/s10600-025-04778-0","url":null,"abstract":"<p>The glucoarabinogalactan GAG-Sco with MM 15 kDa was obtained by fractionation of water-soluble polysaccharides from <i>Scutellaria comosa</i> Juz<i>.</i> An analysis of the monosaccharide residues showed that GAG-Sco consisted of arabinose (35.7%), glucose (25.8%), and galactose (27.7%). Chemical analyses and <sup>1</sup>H and <sup>13</sup>C NMR spectroscopic data found that the main chain of the GAG-Sco macromolecule consisted of 1,6-bound D-galactopyranosyl residues. A side chain in the C-2 position contained glucose, arabinose, and the oligosaccharide fragment <i>α-</i>Ara<i>f</i>-(5→1)-<i>α</i>-Ara<i>f</i>. The water-soluble polysaccharide from S. comosa was shown to affect phagocytosis, specifically the phagocytic index of neutrophils.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 5","pages":"866 - 872"},"PeriodicalIF":0.9,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Constituent Composition and Antimicrobial Activity of Essential Oil from Crataegus songarica 松香山楂挥发油的成分、成分及抑菌活性研究
IF 0.9 4区 化学
Chemistry of Natural Compounds Pub Date : 2025-07-31 DOI: 10.1007/s10600-025-04770-8
Kh. M. Bobakulov, D. R. Siddikov, M. S. Zokirova, S. Zokirov, B. S. Okhundedaev, S. A. Sasmakov, Sh. S. Azimova, E. Kh. Botirov
{"title":"Constituent Composition and Antimicrobial Activity of Essential Oil from Crataegus songarica","authors":"Kh. M. Bobakulov,&nbsp;D. R. Siddikov,&nbsp;M. S. Zokirova,&nbsp;S. Zokirov,&nbsp;B. S. Okhundedaev,&nbsp;S. A. Sasmakov,&nbsp;Sh. S. Azimova,&nbsp;E. Kh. Botirov","doi":"10.1007/s10600-025-04770-8","DOIUrl":"10.1007/s10600-025-04770-8","url":null,"abstract":"","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 4","pages":"817 - 820"},"PeriodicalIF":0.9,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145171606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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