长笛草新合成的双酰胺及其与Akt的分子对接研究

IF 0.9 4区化学 Q4 CHEMISTRY, MEDICINAL

Chemistry of Natural Compounds Pub Date : 2025-09-19 DOI:10.1007/s10600-025-04794-0

Zhengwen Wang, Qiaoyu Yuan, Wei Song, Runlin Xiang, Xinqiao Liu, Zhiliang Ma

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引用次数: 0

摘要

从长叶胡椒果实中分离到一种新的生物碱双胡椒酰胺H(1)和一种已知的生物碱双胡椒酰胺F(2)。这些化合物的化学结构是通过广泛的光谱分析确定的。此外，分子对接结果表明化合物1可能具有抗炎抑制剂的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

A New Bisamide from Piper longum and its Molecular Docking Study with Akt

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A New Bisamide from Piper longum and its Molecular Docking Study with Akt

A new alkaloid, dipiperamide H (1) and a known alkaloid, dipiperamide F (2), were isolated from the fruits of Piper longum L.. The chemical structures of these compounds were identified by extensive spectroscopic analyses. Furthermore, the molecular docking results indicate that compound 1 may act as an anti-inflammatory inhibitor.

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来源期刊

Chemistry of Natural Compounds 化学-有机化学

CiteScore

1.40

自引率

25.00%

发文量

265

审稿时长

7.8 months

期刊介绍： Chemistry of Natural Compounds publishes reviews and general articles about the structure of different classes of natural compounds, the chemical characteristics of botanical families, genus, and species, to establish the comparative laws and connection between physiological activity and the structure of substances.