Clinical Nursing Research最新文献

{"title":"Quality of Life, Mood Disturbance, and Sexual Health in Implantable Cardioverter Defibrillators Recipients.","authors":"Rosa Amelia Herrera Viancha, Sueny Paloma Lima Dos Santos, Olga Rocío Gómez Ortega, Magda Lucia Flórez Flórez, Wendy C Moore, Cindy Tofthagen","doi":"10.1177/10547738251347417","DOIUrl":"https://doi.org/10.1177/10547738251347417","url":null,"abstract":"<p><p>Implantable Cardioverter Defibrillators (ICDs) are essential for managing life-threatening arrhythmias but can impact patients' quality of life (QoL), mood, and sexual health. Although QoL may improve shortly after implantation, factors such as age, psychological state, and ICD shocks can influence long-term outcomes. Anxiety, depression, and fears around physical and sexual activity are common among ICD patients, yet the depth of these effects remains underexplored. This cross-sectional, correlational study examined associations between QoL, mood, and sexual health in 30 adult ICD patients (ages 27-83) within 3 years postimplantation, recruited from a Southeastern U.S. academic medical center. Participants completed the SF-36, Profile of Mood States, and Multidimensional Sexuality Questionnaire. Spearman's correlations indicated that lower QoL was significantly associated with higher mood disturbance (rho = -0.645, <i>p</i> < .001) and lower sexual health (rho = 0.535, <i>p</i> = .005), though no significant link was found between mood disturbance and sexual health (rho = -0.279, <i>p</i> = .168). Multiple linear regression confirmed that QoL was influenced by both mood and sexual health. Post-hoc power analysis using EpiData verified that the sample size (<i>n</i> = 30) provided 90% power with a 5% error rate. These findings underscore the importance of addressing emotional and sexual well-being in ICD patient care. Targeted interventions could improve outcomes, but further research with larger samples is needed to deepen understanding of these relationships.</p>","PeriodicalId":50677,"journal":{"name":"Clinical Nursing Research","volume":" ","pages":"10547738251347417"},"PeriodicalIF":1.7,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Moderation Effects of Race on the Relationship Among Sex Hormones, Biomarkers, and Psychological Symptoms in Female Older Adults.","authors":"Se Hee Min, Maxim Topaz, Chiyoung Lee, Rebecca Schnall","doi":"10.1177/10547738251344980","DOIUrl":"https://doi.org/10.1177/10547738251344980","url":null,"abstract":"<p><p>With aging, female older adults experience biochemical changes such as drop in their sex hormones and biomarkers and often encounter stress, which can be manifested in psychological symptoms. Previous literature has confirmed that racial/ethnic differences exist in the interactive relationship between sex hormones, biomarkers, and psychological symptoms. Yet, the racial/ethnic differences in their interactive relationship have not yet been examined. This is a secondary data analysis using the cross-sectional data of Wave II (2010-2011) from the National Social Life, Health, and Aging Project (NSHAP), and included 1,228 female older adults without moderate to severe cognitive impairment. Moderated network analysis was conducted with race as a moderator to examine the interactive relationship among sex hormones, biomarkers, and psychological symptoms and to compare the differences between the White and non-White group. The White group had a more positive relationship between total hemoglobin and cognition (edge weight = 0.18; moderated edge weight = 0.22). The non-White group had a positive relationship between progesterone and anxiety (edge weight = 0.05; moderated edge weight = 0.04) and between estradiol and cognition (edge weight = 0.03; moderated edge weight = 0.03), both of which were not present in the White group. We found a small moderated effect of race, and the strength of relationship among sex hormones, biomarkers, and psychological symptoms was different between the White and non-White group. Our study offers important preliminary findings to understand the potential racial/ethnic disparities that exist among sex hormones, biomarkers, and psychological symptoms in female older adults and the need to take an interactive approach.</p>","PeriodicalId":50677,"journal":{"name":"Clinical Nursing Research","volume":" ","pages":"10547738251344980"},"PeriodicalIF":1.7,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Delay and Ischemic Stroke Prognosis: A Systematic Review and Meta-Analysis.","authors":"Tong Zhang, Jiangxia Qin, Yanru Chen, Jianhui Dong, Tingting Yang, Hongyan Zhang, Yuxia Ma, Lin Han","doi":"10.1177/10547738251344818","DOIUrl":"https://doi.org/10.1177/10547738251344818","url":null,"abstract":"<p><p>The influence of patient delay on prognosis in patients with ischemic stroke remains unclear. We conducted a systematic review and meta-analysis to determine the association of patient delay with the prognostic outcome of ischemic stroke. PubMed, Web of Science, Embase, Cochrane Library, CNKI, CBM, Wanfang Database, and VIP Database were comprehensively searched from inception to July 24, 2022. All case-control studies, cohort studies, and randomized controlled trials that met the inclusion criteria were retrieved; additionally, manual retrieval and literature tracing were performed. Two reviewers independently screened literature, extracted data, and evaluated the risk of bias in the included studies. Revman 5.3.5 software was used for meta-analysis. We included 14 studies (11 cohort studies and 3 case-control studies) involving 25,337 patients. The results of meta-analysis revealed that the delayed visit group of patients with ischemic stroke had a higher mortality rate, readmission rate, stroke recurrence rate, and adverse outcomes rate than the timely visit group. Among them, mortality (<i>OR</i> = 2.03, 95% CI [1.13, 3.65], <i>p</i> = .02), readmission (<i>OR</i> = 8.17, [4.70, 14.21], <i>p</i> < .001), stroke recurrence rate (<i>OR</i> = 2.66, [1.51, 4.69], <i>p</i> < .001), and adverse outcomes rate (<i>OR</i> = 2.07, [1.18, 3.61], <i>p</i> < .001), respectively. There was no statistical difference in the National Institute of Health Stroke Scale score difference between the delayed visit group and the timely visit group (<i>MD</i> = 1.12, [-0.62, 2.86], <i>p</i> = .21). Patient delay affects the prognosis of patients with ischemic stroke and increases the risk of death, readmission, stroke recurrence, and adverse outcomes. In the future, more in-depth research is needed to verify and expand our research results.</p>","PeriodicalId":50677,"journal":{"name":"Clinical Nursing Research","volume":" ","pages":"10547738251344818"},"PeriodicalIF":1.7,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mediating Effect Analysis of Social Connectedness Between Fear of Progression and Sleep Quality in Patients With Chronic Heart Failure.","authors":"Yan Li, Jiamin Li, Jingwen Qin, Sixin Zhou, Kaizheng Gong","doi":"10.1177/10547738251344666","DOIUrl":"https://doi.org/10.1177/10547738251344666","url":null,"abstract":"<p><p>Poor sleep quality is prevalent among patients with chronic heart failure (HF), with fear of progression being one of its independent predictors. However, the pathways through which it exerts its influence have not been fully elucidated. A total of 246 patients with chronic HF, hospitalized in the cardiology department of a hospital from January to June 2024, were selected for this study using a convenience sampling method. Data were collected using the General Information Questionnaire, Social Connectedness Scale, the Fear of Progression Questionnaire-Short Form, and the Pittsburgh Sleep Quality Index. Stratified regression analysis was conducted to assess the effects of fear of progression and social connectedness on sleep quality. The mediating effect of social connectedness in fear of progression and sleep quality was tested by SPSS PROCESS. The mean age of the patients in this study was 73.84 years (<i>SD</i>, 11.53), with 52.4% being female. The study revealed that patients with chronic HF had sleep quality, fear of progression, and social connectedness had mean scores of 11.83 (<i>SD</i>, 3.76), 29.52 (<i>SD</i>, 7.03), and 3.51 (<i>SD</i>, 0.67), respectively. Regression analysis showed that fear of progression positively predicted poor sleep quality (<i>β</i> = .539, <i>p</i> < .001) and social connectedness negatively predicted poor sleep quality (<i>β</i> = -.301, <i>p</i> < .001). Furthermore, fear of progression exerted an indirect effect on sleep quality through its influence on social connectedness. Social connectedness exerts a significant influence on the relationship between fear of progression (FoP) and sleep quality among chronic HF patients. Enhancing social connectedness potentially offers an effective intervention to ameliorate sleep quality in chronic HF patients exhibiting a high level of FoP.</p>","PeriodicalId":50677,"journal":{"name":"Clinical Nursing Research","volume":" ","pages":"10547738251344666"},"PeriodicalIF":1.7,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meeting Carer Health Information Needs in Mental Health: An Integrative Review.","authors":"Sarah H Son-Theroux, Olivera J Bogunovic","doi":"10.1177/10547738251340883","DOIUrl":"https://doi.org/10.1177/10547738251340883","url":null,"abstract":"<p><p>Family carer involvement in inpatient mental health care is considered beneficial to patient outcomes. Carers and families of patients in inpatient behavioral units often seek basic information about the unit in terms of visiting protocols, communication with staff, questions about the discharge process, and information on local social supports. Recent national and state laws strongly concur that all caregivers, 26% of whom care for those with mental health illness (American Association of Retired Persons [AARP] and National Alliance for Caregiving [NAC]). Recognize, assist, include, support, and engage (RAISE) Family Caregiver Act 2017 directs the Department of Health and Human Services (HHS) to create and make public a road map to support caregivers that includes sharing information. The purpose of this integrative review is to explore the needs and information gaps of carers of individuals hospitalized with mental illness. An integrative review where a detailed search strategy of databases through MeSH and associated terms was conducted between 2017 and 2025. Literature was included if it discussed carer-family, patient, and staff communication in the setting of inpatient behavior health hospitalization. Nine papers met the inclusion criteria and found that current carer information needs are not being met. The following themes were explored: information gap, need for basic information, and empowering caregivers with information. This literature review shows that there is a lack of information and support provided to carers of hospitalized patients with severe mental illness. The literature found that the carer should be treated with respect through the pre-arrangement of carer staff time, listening to carers, and focusing on the provision of recovery-oriented language. Future research should focus on determining if changes to involve families in care, staff training, information packets, required staff meetings or calls to carers, or creating or rewording unit literature to reflect recovery-oriented language would help to meet carer information needs. By addressing information gaps and empowering carers, mental health services can enhance care quality, improve patient outcomes, and strengthen the pivotal role of families in the healing process.</p>","PeriodicalId":50677,"journal":{"name":"Clinical Nursing Research","volume":" ","pages":"10547738251340883"},"PeriodicalIF":1.7,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting Post-ICU Functional Impairment During Early ICU Admission Using Real-world Electronic Health Record Data.","authors":"Anna Krupp, You Wang, Chao Wang, Nicholas M Mohr, Laura Frey-Law, Barbara Rakel","doi":"10.1177/10547738251342845","DOIUrl":"https://doi.org/10.1177/10547738251342845","url":null,"abstract":"<p><p>Intensive care unit (ICU) survivors increasingly report new or worsening functional impairment at hospital discharge. Early risk identification models that include high-dimensional nursing data may improve the delivery of preventive interventions. This study aims to develop and validate models predicting functional impairment at hospital discharge (Activity Measure for Post Acute Care [AMPAC] score <18) using electronic health record (EHR) data from the first 48 h of ICU admission. We identified 799 sepsis survivors hospitalized in the ICU (April 2016-May 2020) from a Midwestern health system's data warehouse. We extracted demographics, illness severity, nursing assessments, and ICU interventions. Given the limited availability of real-world EHR data, we employed CTAB-GAN, a generative adversarial network, to synthesize training data, enabling more robust model development. After feature engineering, 53 of 99 features were selected. We trained an eXtreme Gradient Boosting (XGBoost) classification model and used SHapley Additive exPlanations (SHAP) analysis to identify key predictors. Model performance was evaluated using the area under the receiver operating characteristic curves (AUC). For the 24-h model, the most critical features were first documented AMPAC score, age, mobility level, Braden Scale score, and walking device, while the 48-h model added body mass index and sequential organ failure assessment (SOFA) score as key predictors. Leveraging these findings, lightweight models were constructed using only the most important (top 5/10) predictors, which achieved results comparable to the full predictor model, with AUCs of 0.83 (24 h) and 0.83 (48 h), respectively. Our model, which includes patient characteristics and nurse assessments, can identify patients during early ICU admission who are at high risk for functional impairment at hospital discharge. Our streamlined modeling approach highlights the potential for integration into EHR systems, providing a practical and efficient tool for clinical decision support while maintaining predictive accuracy.</p>","PeriodicalId":50677,"journal":{"name":"Clinical Nursing Research","volume":" ","pages":"10547738251342845"},"PeriodicalIF":1.7,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining Health Literacy and Appropriateness of Commercially Developed Patient Education Materials for Adults Living With Diabetes on the U.S./Mexico Border.","authors":"Shiloh A Williams, Shih-Fan Lin, Stephen Jaime, Beverly Carlson, Maria Keckler","doi":"10.1177/10547738251343418","DOIUrl":"https://doi.org/10.1177/10547738251343418","url":null,"abstract":"<p><p>Effective patient education is critical to an individual's treatment plan when living with diabetes, a debilitating disease requiring extensive knowledge and skills to effectively manage and prevent future morbidity. This descriptive, cross-sectional study assessed the appropriateness of commercially developed patient education materials for rural adults with diabetes. Using electronic health record data from patients (<i>n</i> = 132) with documented health literacy levels (HLL), their HLL scores were reviewed for suitability of educational materials provided by a single rural-border hospital. HLL was measured using the Newest Vital Sign, while educational materials were assessed by two independent reviewers using the Patient Education Materials Assessment Tool for Printable Materials to measure understandability and actionability, and the Simple Measure of Gobbledygook to measure the readability level of documents in both English and Spanish. The mean HLL for Spanish speakers (<i>n</i> = 77) was 2.01 (±1.56), while the mean HLL for English speakers (<i>n</i> = 55) was 2.09 (±1.46), indicating a high likelihood of low health literacy. The materials were evaluated with the English materials achieving an understandability score of 83.33% and an actionability score of 60.00%. By contrast, the Spanish materials scored lower, 61.54% and 20.00%, respectively. In addition, the readability of the materials measured a 9.0 grade level for English materials and a slightly higher 10.8 for Spanish materials. These findings highlight a significant discrepancy between the HLL and the appropriateness of educational materials for the sample population. Although commercially available educational products may provide a budget-concise solution to patient education, particularly in low-resourced organizations, they fail to address the health education needs of the individuals who receive them. Despite the project's limited sample size and single geographical location, it underscores the importance for healthcare organizations to address the health education needs of their communities.</p>","PeriodicalId":50677,"journal":{"name":"Clinical Nursing Research","volume":" ","pages":"10547738251343418"},"PeriodicalIF":1.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonlinear Relationship Between Vital Signs and Hospitalization/Emergency Department Visits Among Older Home Healthcare Patients and Critical Vital Sign Cutoff for Adverse Outcomes: Application of Generalized Additive Model.","authors":"Se Hee Min, Jiyoun Song, Lauren Evans, Kathryn H Bowles, Margaret V McDonald, Sena Chae, Sridevi Sridharan, Yolanda Barrón, Maxim Topaz","doi":"10.1177/10547738251336488","DOIUrl":"https://doi.org/10.1177/10547738251336488","url":null,"abstract":"<p><p>Previous studies have focused on identifying risk factors for older adults receiving home healthcare services without considering vital signs. This may provide important information on deteriorating health conditions that may lead to hospitalization and/or emergency department (ED) visits. Thus, it is important to understand the relationship between vital signs and hospitalization and/or ED visits and critical vital sign points for mitigating the higher risks of hospitalization and/or ED visits. This secondary data analysis uses cross-sectional data from a large, urban home healthcare organization (<i>n</i> = 61,615). A generalized additive model was used to understand the nonlinear relationship between each vital sign and hospitalization and/or ED visits through three unadjusted and adjusted models, and to identify a critical vital sign point related to a higher risk of hospitalization and/or ED visits. A significant nonlinear relationship (effective degree of freedom >2.0) was found between systolic, diastolic blood pressure, heart rate, hospitalization, and/or ED visits. The critical inflection point for systolic blood pressure was 120.36 (SE 3.625, <i>p</i> < .001), diastolic blood pressure was 72.00 (SE 3.108, <i>p</i> < .001), and heart rate was 83.24 (SE 1.994, <i>p</i> = .052). Among all vital signs, the risk of hospitalization and/or ED visits sharply increased when an older adult's heart rate surpassed 83.24 bpm. Our findings reveal that vital signs may serve as a critical indicator of a patient's clinical condition, especially related to hospitalization and/or ED visit. Clinicians need to be cognizant of these critical thresholds for each vital sign and monitor any deviations from baseline to preempt adverse outcomes.</p>","PeriodicalId":50677,"journal":{"name":"Clinical Nursing Research","volume":" ","pages":"10547738251336488"},"PeriodicalIF":1.7,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When Psychiatric Services Become a Waiting Room: Situational Analysis of Involuntary Commitment and Treatment as Experienced by Patients and Nurses.","authors":"Pierre Pariseau-Legault, David Pelosse, Emmanuelle Bernheim, Marie-Hélène Goulet, Guillaume Ouellet, Lisandre Labrecque-Lebeau, Jean-Daniel Jacob, Dave Holmes","doi":"10.1177/10547738251321067","DOIUrl":"10.1177/10547738251321067","url":null,"abstract":"<p><p>A growing body of literature highlights the involvement of nurses in the application of involuntary commitment and treatments in psychiatry. The violence underlying these coercive practices is often discussed, as they infringe on human rights and have negative effects on both patients and healthcare staff. The current state of knowledge on this subject, however, fails to inform us of what characterizes and influences these practices in psychiatric nursing. A situational analysis was conducted to gain a better understanding of this issue. This qualitative research aims to explore the characteristics of nursing care during involuntary commitment and treatments. In all, 10 nurses (<i>n</i> = 10) and 11 patients (<i>n</i> = 11) participated in semi-structured interviews and completed a sociodemographic questionnaire. Data analysis followed a grounded theory approach, involving a process of coding, conceptualizing, categorizing, constant comparison, and relational mapping, accompanied by analytical memos. Four conceptual categories emerged from data analysis: (1) Psychiatry as a waiting room, (2) nurses as subordinates, (3) nothing else but medication, and (4) resisting undignifying care. The results suggest that clinical issues surrounding involuntary commitment and treatments can be explained by how care is conceived. The psychiatric nursing practice seems to be limited to the application of coercive power, such as forced administration of medication. The distress potentially induced by involuntary commitment and treatments in patients comes to be ignored in favor of compliance with the legal procedures. The results describe a situation where patients felt abandoned to those procedures as if refusing to be hospitalized or treated were incompatible with any other form of care. Several participants also report having suffered negative consequences following one or more coerced psychiatric episodes. For them, refusal of care therefore seems to be associated with a resistance against the current violence of biomedical psychiatry, rather than a refusal to obtain help and support.</p>","PeriodicalId":50677,"journal":{"name":"Clinical Nursing Research","volume":" ","pages":"168-178"},"PeriodicalIF":1.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12053111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors and Predictors for Persistent Dyspnea Post-COVID-19: A Systematic Review.","authors":"Sandra Morgan, James M Smith, Bini Thomas, Maria Moreno, Constance Visovsky, Theresa Beckie","doi":"10.1177/10547738251314076","DOIUrl":"10.1177/10547738251314076","url":null,"abstract":"<p><p>The most frequently reported post-coronavirus disease of 2019 (COVID-19) symptoms include shortness of breath, fatigue, and cognitive disturbances, with reports of persistent dyspnea ranging between 26% and 41%. There is an urgent need to understand the risk factors and predictors for persistent COVID-19 dyspnea in individuals at all levels of COVID-19 illness severity, to enable the implementation of targeted interventions for those likely to be most affected with persistent dyspnea. Thus, the purpose of this systematic review is to explore the risk factors and predictors that are associated with persistent dyspnea in the post-COVID-19 population. This review was performed according to the Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines and registered prospectively in PROSPERO as CRD42023466713. A search strategy was conducted across <i>PubMed, CINAHL, Web of Science</i>, and <i>EMBASE</i> databases, that included studies conducted from 2020 to March 2024. The Covidence platform was used for screening studies, scoring methodologic quality, and performing data extraction using a two-step independent review process. This review included 33 studies, addressing 83,920 participants across 20 countries. The strongest predictive risk factors for persistent dyspnea included the following: female sex, elevated body mass index, pulmonary comorbidities, pre-existing anxiety and depression, pre-COVID-19 physical limitations, the severity of the COVID-19 illness, and socioeconomic differences. Potential risk factors included increased age, smoking history, and COVID-19 variant type. The presence of biomarkers for persistent dyspnea in the post-COVID-19 population can be used by clinicians to prospectively identify those individuals who should be flagged. Early identification may then be leveraged for timely referral for prophylactic and rehabilitative interventions for dyspnea. A personalized plan to target those risk factors that are modifiable should follow.</p>","PeriodicalId":50677,"journal":{"name":"Clinical Nursing Research","volume":" ","pages":"195-212"},"PeriodicalIF":1.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}