V. Isnardi , N. Jehanno , T. Cassou-Mounat , B. Jonca , P. Marec Berard
{"title":"Apport de la TEP-TDM FDG dans la prise en charge des sarcomes osseux en pédiatrie","authors":"V. Isnardi , N. Jehanno , T. Cassou-Mounat , B. Jonca , P. Marec Berard","doi":"10.1016/j.mednuc.2025.06.005","DOIUrl":"10.1016/j.mednuc.2025.06.005","url":null,"abstract":"<div><div>Bone sarcomas, including osteosarcomas (OS) and Ewing sarcomas (ES), are rare but aggressive tumors requiring specialized care. Among the available imaging techniques, FDG PET-CT (PET FDG) has taken a significant role in this oncological field in recent years. It has been established for the initial staging due to its high sensitivity for detecting extrapulmonary metastases, particularly for detecting bone and bone marrow involvement. The use of PET FDG is also developing for the evaluation of therapeutic response to neoadjuvant chemotherapy and systemic treatments in patients with advanced metastatic disease. PET FDG offers better availability and fewer acquisition constraints compared to whole-body MRI, which is important for managing a pediatric population. Furthermore, the latest technological advances will improve radiation protection for these young patients.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"49 4","pages":"Pages 244-248"},"PeriodicalIF":0.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144766458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prise en charge du lymphome en médecine nucléaire chez l’enfant : actualisation et particularité des lymphomes chez l’enfant","authors":"Y. Al Tabaa , A. Théron","doi":"10.1016/j.mednuc.2025.06.006","DOIUrl":"10.1016/j.mednuc.2025.06.006","url":null,"abstract":"<div><div>Pediatric lymphomas account for 10–15% of childhood cancers, with treatment approaches tailored to histological subtypes such as Hodgkin lymphoma (HL), and non Hodgkin lymphomas (NHL), including Burkitt lymphoma, diffuse large B-cell lymphoma (DLBCL), and primary mediastinal B-cell lymphoma. The introduction of 18F-FDG-PET imaging has significantly transformed diagnostic and therapeutic strategies. PET enables accurate initial staging, early response assessment, and contributes to treatment de-escalation, especially in HL through Euronet protocols. In Burkitt lymphoma, PET's role is limited due to the urgency of treatment, though its high negative predictive value (93%) is notable. Pediatric DLBCL, being less aggressive, allows for PET-guided management analogous to adult practice. In primary mediastinal lymphoma, common in adolescents, interpretation challenges arise from residual low-grade metabolic uptake post-treatment, often reflecting inflammation rather than active disease. FDG-PET has become essential in personalizing pediatric lymphoma care, refining staging, and reducing overtreatment. Combined with recent advances in targeted therapies – such as anti-CD20 antibodies and CAR-T cells – this approach improves survival outcomes while minimizing long-term toxicity.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"49 4","pages":"Pages 249-255"},"PeriodicalIF":0.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144766459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Boîterie fébrile chez l’enfant","authors":"A. Bourdon, T. Paunet","doi":"10.1016/j.mednuc.2025.06.004","DOIUrl":"10.1016/j.mednuc.2025.06.004","url":null,"abstract":"<div><div>Febrile limping in children is a common clinical condition in pediatrics, requiring prompt diagnostis and therapeutic management. It can reveal different diseases including osteomyelitis and septic arthritis which need urgent medical attention to prevent potentially severe complications. This article attempts to illustrate various scintigraphic presentations of febrile limping using clinical cases.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"49 4","pages":"Pages 234-236"},"PeriodicalIF":0.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144766456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Les spécificités de la prise en charge des enfants en médecine nucléaire","authors":"L. Turpin","doi":"10.1016/j.mednuc.2025.06.001","DOIUrl":"10.1016/j.mednuc.2025.06.001","url":null,"abstract":"<div><div>Après un rappel sur la problématique de l’exposition aux rayonnements ionisants chez les enfants, cet article décrit les principes généraux de gestion d’un examen scintigraphique en pédiatrie. L’article précise les modalités de gestion de l’anxiété et de la douleur chez les enfants et détaille les principes de communication (adaptée à l’âge) et de création d’un environnement médical favorable à la bonne réalisation d’une procédure de médecine nucléaire pédiatrique, depuis l’injection du radiopharmaceutique jusqu’aux acquisitions des images. Le positionnement de l’enfant, son hydratation et la gestion de ces mictions constituent également des facteurs garantissant l’obtention d’images de qualité optimale pour l’interprétation.</div></div><div><div>By revisiting the question of the exposure of pediatric populations to ionizing radiation, this manuscript explains the fundamental principles governing the administration of nuclear medicine procedures in the pediatric population. The discourse defines strategies to alleviate anxiety and discomfort in young patients and outlines communication principles appropriate to developmental stages, as well as the establishment of a supportive medical environment that facilitates the effective execution of pediatric nuclear medicine interventions, from radiopharmaceutical injection to the image acquisition phase. In addition, the positioning of the pediatric patient, as well as the appropriate management of hydration and urination, are essential elements that ensure that high-quality images are obtained for later interpretation.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"49 4","pages":"Pages 215-218"},"PeriodicalIF":0.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144766452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prise en charge d’une suspicion de maltraitance infantile : le point de vue du clinicien","authors":"L. Veneau","doi":"10.1016/j.mednuc.2025.06.003","DOIUrl":"10.1016/j.mednuc.2025.06.003","url":null,"abstract":"<div><div>Child abuse encompasses all forms of physical, psychological or sexual mistreatment inflicted on a child. This article discusses the diagnostic approach in cases of suspected child abuse. It then outlines the main aspects of care, the coordination between medical, social, and judicial actors, and the importance of reporting to the authorities in order to protect a minor efficently.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"49 4","pages":"Pages 219-221"},"PeriodicalIF":0.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144766453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prise en charge d’une suspicion de maltraitance chez l’enfant : le point de vue du médecin nucléaire","authors":"B. Jonca","doi":"10.1016/j.mednuc.2025.06.007","DOIUrl":"10.1016/j.mednuc.2025.06.007","url":null,"abstract":"<div><div>In the context of child abuse, post-traumatic bone lesions are the most commonly observed after cutaneous lesions. Therefore, imaging has an important role to play in diagnosis, especially among the youngest children. Several imaging modalities are now available. While standard radiographs are essential and remain the first-line test, bone scintigraphy is useful for detecting certain recent infra-radiological lesions and types of fractures. Some fractures are more common in the setting of non-accidental trauma, but there is no single pathognomonic lesion. It is the association of multiple fractures associated with the absence of a concordant lesion mechanism that can lead to the diagnosis. The presence of fractures of different ages is an important, but unfortunately, inconsistent diagnostic factor. Bone scans alone do not allow accurate lesion dating. Prompt and multidisciplinary management, high quality imaging and accurate interpretation are essential to the diagnosis of child abuse.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"49 4","pages":"Pages 225-233"},"PeriodicalIF":0.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144766455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prise en charge de la maladie de Basedow dans l’Ouest algérien","authors":"I. Sefraoui Khelil , M. Chakouri","doi":"10.1016/j.mednuc.2025.04.002","DOIUrl":"10.1016/j.mednuc.2025.04.002","url":null,"abstract":"<div><div>Hyperthyroidism is a pathological condition marked by an excess of thyroid hormones in the bloodstream. The most common observed etiology is Graves’ disease. In order to establish the epidemiological profile of this disease in the Algerian west and evaluate its treatment in nuclear medicine, we conducted a retrospective, cross-sectional study from January 2014 to December 2023 at the University Hospital Establishment of Oran, including 180 folders of patients suffering from hyperthyroidism. We report a high prevalence of Graves’ disease (98.33%) with a notable female predominance of 72.88%. A peak incidence is noted across all genders between the ages of 31 and 50. In Algeria, radiotherapy with iodine 131 is generally indicated as a second line after antithyroid drugs treatment. In our study, one hundred and sixty-five patients have received radioactive activities administered empirically (extremes: 8–28 mCi). An activity below 15 mCi was administered to 67.27% of patients, between 15 mCi and 20 mCi to 30.3% of patients, and only 2.42% received an activity exceeding 20 mCi. A single dose was administered in 98.18% of cases, while only three patients (1.82%) received a second. Finally, the RAI therapy was successful in 85.83% of cases over a follow-up period ranged between 1 and 9 months. These observed results are promising and encourage healthcare professionals to consider the radiotherapy as an early treatment of Graves’ disease.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"49 5","pages":"Pages 278-283"},"PeriodicalIF":0.2,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145120201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Connaissances et perception de la médecine nucléaire par les médecins exerçant au Bénin en 2024","authors":"G.D. Houndetoungan , O.H. Fachinan , M.K.E. Hounkponou , C.A. Obey , B.F. Agboton , Y.F. Djohoun , G. Abogbo , T. Seguedeme , K.M. Amoussou-Guenou","doi":"10.1016/j.mednuc.2025.04.001","DOIUrl":"10.1016/j.mednuc.2025.04.001","url":null,"abstract":"<div><div>The aim of this study was to assess the knowledge and perception of nuclear medicine among physicians practicing in Benin. This was a descriptive and analytical cross-sectional study conducted from December 2023 to July 2024. Knowledge of nuclear medicine was evaluated using a scoring system based on questions addressing the definition, components, and indications of this specialty. A total of 316 participants were included in the study. Their median age was 29.81 years (range: 22–56 years). Among them, 49.05% were specialists or in the process of specialization. Additionally, 22.15% of the participants had completed internships abroad. Regarding knowledge levels, 0.32% of respondents demonstrated a good level, 12.34% a moderate level, 22.47% an insufficient level, and 64.87% a poor level. Factors associated with an acceptable level of knowledge included having completed an internship abroad and the presence of a nuclear medicine department in the country where general medical training was received. Regarding perception, 67.09% of physicians considered nuclear medicine essential for optimal patient management, and 88.92% expressed a desire for its inclusion in general medical education. Physicians practicing in Benin demonstrated insufficient knowledge of nuclear medicine, primarily due to the limited routine practice of this specialty. However, their perception was favorable, supported by the imminent launch of a new nuclear medicine department at the International Hospital Center of Calavi in Benin.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"49 5","pages":"Pages 260-266"},"PeriodicalIF":0.2,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145120204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Connaissances et perception de la médecine nucléaire par les médecins exerçant au Bénin en 2024","authors":"G.D. Houndetoungan , O.H. Fachinan , M.K.E. Hounkponou , C.A. Obey , B.F. Agboton , Y.F. Djohoun , G. Abogbo , T. Seguedeme , K.M. Amoussou-Guenou","doi":"10.1016/j.mednuc.2025.04.001","DOIUrl":"10.1016/j.mednuc.2025.04.001","url":null,"abstract":"<div><div>The aim of this study was to assess the knowledge and perception of nuclear medicine among physicians practicing in Benin. This was a descriptive and analytical cross-sectional study conducted from December 2023 to July 2024. Knowledge of nuclear medicine was evaluated using a scoring system based on questions addressing the definition, components, and indications of this specialty. A total of 316 participants were included in the study. Their median age was 29.81 years (range: 22–56 years). Among them, 49.05% were specialists or in the process of specialization. Additionally, 22.15% of the participants had completed internships abroad. Regarding knowledge levels, 0.32% of respondents demonstrated a good level, 12.34% a moderate level, 22.47% an insufficient level, and 64.87% a poor level. Factors associated with an acceptable level of knowledge included having completed an internship abroad and the presence of a nuclear medicine department in the country where general medical training was received. Regarding perception, 67.09% of physicians considered nuclear medicine essential for optimal patient management, and 88.92% expressed a desire for its inclusion in general medical education. Physicians practicing in Benin demonstrated insufficient knowledge of nuclear medicine, primarily due to the limited routine practice of this specialty. However, their perception was favorable, supported by the imminent launch of a new nuclear medicine department at the International Hospital Center of Calavi in Benin.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"49 5","pages":"Pages 260-266"},"PeriodicalIF":0.2,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145120197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prise en charge de la maladie de Basedow dans l’Ouest algérien","authors":"I. Sefraoui Khelil , M. Chakouri","doi":"10.1016/j.mednuc.2025.04.002","DOIUrl":"10.1016/j.mednuc.2025.04.002","url":null,"abstract":"<div><div>Hyperthyroidism is a pathological condition marked by an excess of thyroid hormones in the bloodstream. The most common observed etiology is Graves’ disease. In order to establish the epidemiological profile of this disease in the Algerian west and evaluate its treatment in nuclear medicine, we conducted a retrospective, cross-sectional study from January 2014 to December 2023 at the University Hospital Establishment of Oran, including 180 folders of patients suffering from hyperthyroidism. We report a high prevalence of Graves’ disease (98.33%) with a notable female predominance of 72.88%. A peak incidence is noted across all genders between the ages of 31 and 50. In Algeria, radiotherapy with iodine 131 is generally indicated as a second line after antithyroid drugs treatment. In our study, one hundred and sixty-five patients have received radioactive activities administered empirically (extremes: 8–28 mCi). An activity below 15 mCi was administered to 67.27% of patients, between 15 mCi and 20 mCi to 30.3% of patients, and only 2.42% received an activity exceeding 20 mCi. A single dose was administered in 98.18% of cases, while only three patients (1.82%) received a second. Finally, the RAI therapy was successful in 85.83% of cases over a follow-up period ranged between 1 and 9 months. These observed results are promising and encourage healthcare professionals to consider the radiotherapy as an early treatment of Graves’ disease.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"49 5","pages":"Pages 278-283"},"PeriodicalIF":0.2,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145120199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}