Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique最新文献

{"title":"Radiothérapie interne vectorisée et théranostique en France : recommandations de bonnes pratiques par la Société Française de Médecine Nucléaire","authors":"C. Bailly,&nbsp;A.L. Giraudet,&nbsp;L. Turpin,&nbsp;M. Claudin,&nbsp;D. Tonnelet,&nbsp;V. Habouzit,&nbsp;C. Merlin,&nbsp;E. Deshayes,&nbsp;C. Lussey,&nbsp;P. Robin,&nbsp;D. Deandreis,&nbsp;B. Dekyndt,&nbsp;C. Lamesa,&nbsp;A. Dieudonné,&nbsp;J.-N. Badel,&nbsp;F. Courbon,&nbsp;L. Vija","doi":"10.1016/j.mednuc.2026.02.001","DOIUrl":"10.1016/j.mednuc.2026.02.001","url":null,"abstract":"<div><div>Radionuclide therapy is a nuclear medicine treatment that consists of irradiating tumor targets disseminated throughout the body using radiopharmaceuticals labeled with radionuclides emitting ionizing radiation. The rapid expansion of therapeutic indications, driven by the introduction of new molecules, is profoundly transforming the organization and activity of nuclear medicine departments in France. The purpose of this document is to provide a synthesis of the clinical best practices required for the administration of therapeutic radiopharmaceuticals. It has been prepared by the members of the Working Group on radionuclide therapy and theranostics of the French Society of Nuclear Medicine (SFMN), in collaboration with the relevant stakeholders. These recommendations aim to support nuclear medicine departments in the development of radionuclide therapy activity in France, while allowing a degree of flexibility according to local or regional specificities.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"50 4","pages":"Pages 124-130"},"PeriodicalIF":0.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148640240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lymphome nodulaire à prédominance lymphocytaire : état des connaissances et intérêt de la TEP/TDM au 18F-FDG","authors":"S. Rousselet,&nbsp;B. Jonca,&nbsp;F. Chevillon,&nbsp;D. Krzisch,&nbsp;C. Thieblemont,&nbsp;L. Vercellino","doi":"10.1016/j.mednuc.2026.03.001","DOIUrl":"10.1016/j.mednuc.2026.03.001","url":null,"abstract":"<div><div>Nodular lymphocyte-predominant lymphoma (NLPL), formerly referred to as Poppema lymphoma, is a rare lymphoma subtype that has long been considered part of the classical Hodgkin lymphoma (cHL) spectrum because of shared morphological and clinical features. Its definition is currently being reassessed by the scientific community, with the aim of recognizing this lymphoma as a distinct entity. There are currently no specific recommendations regarding staging procedures, treatment strategies, or follow-up for NLPL. Patient management is largely extrapolated from that of cHL, particularly with respect to staging work-up. In this context, ¹⁸F fluorodeoxyglucose positron emission tomography combined with computed tomography (¹⁸F-FDG PET/CT) is now routinely performed at diagnosis. ¹⁸F-FDG PET/CT has demonstrated excellent sensitivity and specificity across a wide range of hematologic malignancies. This narrative review provides an updated overview of current knowledge on NLPL, with a particular focus on the metabolic characteristics of this lymphoma and the role of ¹⁸F-FDG PET/CT in initial staging and during follow-up. Available data indicate that ¹⁸F-FDG PET/CT shows excellent sensitivity for initial staging, with a significant impact on disease staging and potential modification of therapeutic strategies. The metabolic features of NLPL appear to differ from those of cHL, with generally lower standardized uptake values (SUVs). In addition, existing studies suggest that interim PET/CT assessment, particularly using the Deauville score, may have prognostic value in NLPL and could help guide treatment strategies, as is the case in cHL. Taken together, these findings support the need for further prospective studies to confirm these results and to investigate the prognostic value of quantitative PET/CT parameters, such as metabolic tumor volume and tumor dissemination.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"50 4","pages":"Pages 117-123"},"PeriodicalIF":0.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148640237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harmonization of exposure constraints for relatives following targeted radionuclide therapy: A French perspective","authors":"T. Carlier,&nbsp;B. Denizot,&nbsp;N. Prevot-Bitot,&nbsp;C. Nioche,&nbsp;F. Courbon,&nbsp;F. Cachin","doi":"10.1016/j.mednuc.2026.03.002","DOIUrl":"10.1016/j.mednuc.2026.03.002","url":null,"abstract":"<div><div>Targeted radionuclide therapy is being used more and more to treat both benign and malignant pathologies. It is therefore highly desirable to harmonize care practices, particularly with regard to radiation protection rules for relatives and carers. Based on literature data and consensus among the Radiation Protection Group of the SFMN, the proposed methodology uses standardized scenarios and situations for patients and their relatives. When applied to real treatment conditions, it shows low restriction durations for patients treated for thyroid cancer (upon exiting iratherapy chambers) and for LUTATHERA treatments. These durations are particularly significant for patients with benign thyroid diseases and prostate cancer, as well as for pregnant women, young couples and children. Based on a small number of hypotheses and initial data, this work proposes harmonising recommendations for restriction duration through the use of freely available, internet-based software for the entire nuclear medicine community. This software has the potential to be adapted to new radiopharmaceuticals and regulatory situations.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"50 4","pages":"Pages 131-136"},"PeriodicalIF":0.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148640236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pratique de cardiologie nucléaire en Afrique de l’Ouest : revue systématique de la littérature","authors":"M. Toure,&nbsp;N.N. Kouassi-Aboukoua,&nbsp;S. Keita,&nbsp;J.L. One,&nbsp;A.L. Djobo,&nbsp;F.A. Ayegbeu,&nbsp;É.É.G. Zunon-Kipré,&nbsp;N.K.J. N’drin,&nbsp;B.-L. Faussignaux,&nbsp;G.M. Gbogbo,&nbsp;P. Yeo,&nbsp;A. Kouame-Koutouan","doi":"10.1016/j.mednuc.2026.02.002","DOIUrl":"10.1016/j.mednuc.2026.02.002","url":null,"abstract":"<div><h3>Background</h3><div>In West Africa, cardiovascular diseases are rising rapidly due to the epidemiological transition. Yet, nuclear cardiology, crucial for functional diagnosis, remains underdeveloped and poorly documented.</div></div><div><h3>Methods and results</h3><div>A systematic review (MEDLINE, Google Scholar, 1970–2025), conducted according to PRISMA guidelines, identified 13 articles, of which 8 were included. These studies, conducted in Senegal, Burkina Faso, and Niger, all focused on single-photon emission computed tomography (SPECT) applied to coronary artery disease. Reported indications included silent ischemia screening, suspected angina or coronary artery disease, atypical chest pain, and follow-up after myocardial infarction or bypass surgery. The most frequently used radiopharmaceutical was 99mTc-sestamibi, occasionally combined with 99mTc-tetrofosmin. The mean age of patients ranged from 47 to 67 years, with male proportions between 37.8% and 60.27%. Two studies compared SPECT with transthoracic echocardiography. No major adverse events were reported. The most common diagnoses were myocardial ischemia, necrosis, and mixed patterns. Methodological quality was generally satisfactory, although limited by the lack of random sampling and subgroup analyses.</div></div><div><h3>Conclusion</h3><div>Nuclear cardiology in West Africa remains restricted to a few centers and predominantly limited to coronary SPECT imaging. This delay highlights the urgent need for infrastructure investment, specialist training, and protocol harmonization. Expansion of nuclear cardiology could substantially improve cardiovascular disease management in West Africa, where their burden is rapidly increasing.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"50 4","pages":"Pages 137-145"},"PeriodicalIF":0.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148640238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scintigraphie salivaire au 99mTc dans l’évaluation des séquelles tardives post-thérapeutiques des carcinomes du nasopharynx : corrélation dosimétrique et impact sur la qualité de vie (étude tunisienne)","authors":"L. Zaabar ,&nbsp;S. Zarraa ,&nbsp;L. Kchaou ,&nbsp;D. Ben Sellem ,&nbsp;D. Chebil ,&nbsp;S. Kedous ,&nbsp;C. Nasr ,&nbsp;A. Mhiri","doi":"10.1016/j.mednuc.2025.12.001","DOIUrl":"10.1016/j.mednuc.2025.12.001","url":null,"abstract":"<div><h3>Background</h3><div>In Tunisia, intensity-modulated radiotherapy (IMRT) for nasopharyngeal carcinoma (NPC) frequently causes severe late salivary toxicities, significantly impairing patients’ quality of life (QOL). Objective assessment of salivary dysfunction using salivary gland scintigraphy using Tc 99m (^99mTc-SS) remains underutilized.</div></div><div><h3>Objectives</h3><div>This study aimed to evaluate salivary dysfunction using ^99mTc-SS after IMRT, to correlate dysfunction with salivary gland dosimetric parameters, and to quantify its impact on patient QOL.</div></div><div><h3>Methods</h3><div>A single-center cross-sectional study conducted from June to December 2023, included NPC patients in complete remission after IMRT. The assessment combined ^99mTc-SS, measuring uptake rate (UR) and salivary ejection fraction (SEF), with salivary gland dosimetry (mean/maximum doses, V_15Gy, V_30Gy, V_40Gy, D_50%). QOL was assessed using the EORTC QLQ-H&amp;N43 questionnaire (arabic version). Statistical analyses employed Pearson correlation and ANOVA.</div></div><div><h3>Results</h3><div>Among 37 patients (median age: 49 years), 89% reported xerostomia (59% grade 2). ^99mTc-SS (128 glands in 32 patients) identified moderate hypofunction in 48% of glands, significantly more pronounced in submandibular glands (ipsilateral median SEF: 4.5% vs. contralateral: 7%; <em>P</em> <!-->&lt;<!--> <!-->0.05). Xerostomia correlated with submandibular D_max (<em>P</em> <!-->=<!--> <!-->0.034) and treatment spread (<em>P</em> <!-->=<!--> <!-->0.025). Parotid SEF declined with increasing D_mean (<em>r</em> <!-->=<!--> <!-->–0.463; <em>P</em> <!-->=<!--> <!-->0.013), V_30Gy (<em>r</em> <!-->=<!--> <!-->–0.475; <em>P</em> <!-->=<!--> <!-->0.011), V_40Gy (<em>r</em> <!-->=<!--> <!-->–0.571; <em>P</em> <!-->=<!--> <!-->0.002), and D_50% (<em>r</em> <!-->=<!--> <!-->–0.524; <em>P</em> <!-->=<!--> <!-->0.004). QOL was most affected by dry mouth (54.5<!--> <!-->±<!--> <!-->31.82) and dental problems (42.64<!--> <!-->±<!--> <!-->36.61), both exacerbated by xerostomia (<em>P</em> <!-->&lt;<!--> <!-->0.05).</div></div><div><h3>Conclusion</h3><div>It is critical to systematically integrate ^99mTc-SS into post-IMRT monitoring. This approach would optimize glandular preservation strategies and sustainably improve patient well-being.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"50 3","pages":"Pages 95-102"},"PeriodicalIF":0.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147923449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new perspective on regional distribution of metastasis in patients with solitary tumors with bone metastases: A 10-year retrospective study","authors":"F. Tahak ,&nbsp;M. Demı̇ryürek ,&nbsp;M.F. Küçükşen ,&nbsp;Ö. Şahı̇n ,&nbsp;T.S. Çolak","doi":"10.1016/j.mednuc.2026.02.003","DOIUrl":"10.1016/j.mednuc.2026.02.003","url":null,"abstract":"<div><h3>Background</h3><div>The increasing incidence of cancer cases has led to an increase in bone metastases (BM), posing a major public health problem. The aim of this study was to investigate the distribution of BM, skeletal events related (SRE) to metastases and their association with mortality.</div></div><div><h3>Methods</h3><div>The study included data from 13,047 patients who underwent 18F-FDG PET/CT scans at Necmettin Erbakan University Faculty of Medicine Hospital between 2012 and 2022. Patients included in the study were those with solid tumors diagnosed with their first BM during the screening period and were between 18 and 99 years old. Patients with solid tumors without BM, primary bone tumors, childhood cancers, and incomplete data records were excluded.</div></div><div><h3>Results</h3><div>Multiple BM were detected in 80.1% of patients. When we looked at cancer patients with BM, the first metastasis was most commonly to the spine (85.8%), the second bone metastasis was most commonly to the scapula (33.1%) and the third BM was most commonly to the femur (51.2%). SRE to metastasis occurred in 45.8% of patients. The average time from diagnosis to the first metastasis was 13.4<!--> <!-->±<!--> <!-->23.2 months, the average time to the second metastasis was 33.8<!--> <!-->±<!--> <!-->30.6 months, and the average time to the third metastasis was 49.3<!--> <!-->±<!--> <!-->33.6 months.</div></div><div><h3>Conclusion</h3><div>Our study showed that the most common site of cancer involvement was the spine, secondary metastasis was most common in the scapula and tertiary metastasis was most common in the femur.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"50 3","pages":"Pages 103-110"},"PeriodicalIF":0.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147923450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of 18F-FDG PET/CT imaging in the strategic selection of the accessory spleen as a biopsy site for definitive lymphoma diagnosis in a 67-year-old man: A Case report","authors":"E.B. Erdogan ,&nbsp;G. Çetin ,&nbsp;C.Y. Yozgat ,&nbsp;S. Koca ,&nbsp;M. Aydın","doi":"10.1016/j.mednuc.2025.09.010","DOIUrl":"10.1016/j.mednuc.2025.09.010","url":null,"abstract":"<div><div>The role of ¹⁸F-FDG PET/CT in lymphoma staging and treatment response assessment is well established in the literature. Beyond these conventional applications, it can also serve as a powerful tool for guiding biopsy decisions in diagnostically challenging cases. We present the case of a 67-year-old man with suspected lymphoma, in whom initial diagnostic procedures—including bone marrow aspiration—failed to yield conclusive results. A multidisciplinary team utilized ¹⁸F-FDG PET/CT to identify an accessory spleen exhibiting metabolic activity comparable to the primary spleen. Given its accessibility and diagnostic potential, the accessory spleen was surgically excised, leading to a definitive diagnosis of mantle cell lymphoma. This case underscores the strategic role of PET/CT in biopsy site selection, offering a safer and less invasive diagnostic alternative and reinforcing its crucial role in lymphoma management.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"50 3","pages":"Pages 111-113"},"PeriodicalIF":0.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147923451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidental detection of medullary thyroid carcinoma on Ga-68 PSMA PET/MRI in a patient with prostate cancer","authors":"S. Gülbahar Ateş,&nbsp;U. Aydos,&nbsp;L.Ö. Atay","doi":"10.1016/j.mednuc.2026.01.191","DOIUrl":"10.1016/j.mednuc.2026.01.191","url":null,"abstract":"<div><div>A 73-year-old male patient with prostate cancer underwent a staging Gallium-68 (Ga-68) prostate-specific membrane antigen (PSMA) positron emission tomography/magnetic resonance imaging (PET/MRI). Ga-68 PSMA PET/MRI revealed cervical and mediastinal lymph nodes, and a thyroid mass with moderately increased uptake, as well as extensive metastases of prostate cancer. The thyroid mass and lymph nodes were assessed suspicious for a second primary thyroid cancer due to their relatively lower radiotracer uptake. Pathological examination demonstrated multifocal medullary thyroid carcinoma (MTC) with multiple lymph node metastases. Our case highlights incidental detection of MTC on Ga-68 PSMA PET, likely related to PSMA expression in tumor-associated neovasculature. PSMA-targeted imaging and radioligand therapy could provide new diagnostic and therapeutic opportunities in patients with MTC.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"50 3","pages":"Pages 114-116"},"PeriodicalIF":0.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147923452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facteurs prédictifs de l’efficacité de l’irathérapie chez les patients porteurs de métastases pulmonaires de cancer différencié de la thyroïde de souche folliculaire","authors":"M. Ben Nasr ,&nbsp;D. Ben Sellem","doi":"10.1016/j.mednuc.2025.09.011","DOIUrl":"10.1016/j.mednuc.2025.09.011","url":null,"abstract":"<div><div>Ten to 15% of patients with differentiated follicular thyroid carcinoma (DTC) develop micro- or macronodular lung metastases (LM). Iodine 131 is the key treatment of these metastases. The aim of the study was to assess the efficacy of radioiodine therapy in LM of DTC, and to identify predictive factors of response. This was a retrospective and descriptive study, including patients operated for DTC presenting synchronous or metachronous LM, between 1996 and 2019. The number of patients included was 29 (8 children and 21 adults). The mean age was 39 years (ranging from 5 to 82 years). Papillary carcinoma was the most frequent histological type. LM were miliary in 14 cases and nodular in 15. The administered activity was 3.7 GBq in 80% of cases. The number of courses of radioiodine therapy varied from 3 to 12, with an average of 6.1. The response to treatment was complete in 10 patients, partial in 4 others and absent in the last 15. The efficacy rate was 48%. Univariate analysis showed that young age at diagnosis, type of LM and initial iodine avidity were the most significant factors associated with therapeutic efficacy (<em>P</em> <!-->=<!--> <!-->0.008; &lt; 0.001 and &lt; 0.001 respectively). Most LM of DTC respond to radioiodine therapy, either completely or partially, especially the iodine-avid micronodular metastases of young patients. Radioiodine therapy should be continued as long as lesions continue to present radioiodine uptake.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"50 3","pages":"Pages 87-94"},"PeriodicalIF":0.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147923830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydronéphrose du pyélon supérieur d’une duplication rénale de découverte fortuite simulant des kystes parapyéliques : à propos d’un cas","authors":"M. El Amrani,&nbsp;H. Bensimimou,&nbsp;F. M’hamdi,&nbsp;H. Aschawa,&nbsp;A. Guensi","doi":"10.1016/j.mednuc.2026.01.086","DOIUrl":"10.1016/j.mednuc.2026.01.086","url":null,"abstract":"<div><h3>Introduction</h3><div>La duplication rénale (DU) est une uropathie congénitale fréquente souvent asymptomatique. Elle peut être associée à des complications obstructives ou un reflux vésico-urétéral. Nous rapportons un cas où la scintigraphie rénale dynamique a permis d’assoir le diagnostic de DU chez une patiente adressée pour kystes parapyéliques et évaluer la fonction des deux entités rénales.</div></div><div><h3>Cas clinique</h3><div>Il s’agit d’une patiente de 62 ans présentant des douleurs lombaires droites avec à l’uroscanner individualisation de kystes parapyéliques bilatéraux. Elle nous était adressée pour complément d’exploration par scintigraphie rénale au 99mTc–MAG3.</div></div><div><h3>Techniques et résultats</h3><div>L’examen a montré une distribution homogène du radiotraceur au niveau des deux reins, une fonction rénale relative symétrique et une vidange complète écartant une atteinte obstructive. On notait une cinétique de drainage différente au niveau des deux entités rénales droites en faveur d’une duplicité rénale. Le rénicule supérieur participait à hauteur de 14 % à la fonction rénale globale et les images tardives montraient une activité pyélique supérieure droite résiduelle.</div></div><div><h3>Discussion</h3><div>La duplication urétérale est l’anomalie des voies urinaires la plus fréquente. Sa prévalence est plus élevée chez les femmes et touche fréquemment le rein gauche. Le segment supérieur peut être obstrué secondairement à une ectopie urétérale ou à la présence d’une urétérocèle ; le segment inférieur est souvent sujet à un reflux vésico-urétéral. L’obstruction de la jonction pyélo-urétérale d’un rein dupliqué est une configuration rare surtout lorsqu’il s’agit du pyélon supérieur. Ceci est probablement dû au fait que la partie inférieure est l’analogue anatomique d’un système unique comprenant les deux tiers du parenchyme, tandis que la partie supérieure, plus petite, ne comprend qu’un ou deux calices mineurs.</div></div><div><h3>Conclusion</h3><div>Notre travail illustre l’intérêt de la scintigraphie rénale dynamique dans le diagnostic d’une duplication urétérale méconnue et l’évaluation de la qualité du drainage au niveau des deux groupes caliciels, permettant une meilleure orientation de la conduite thérapeutique.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"50 1","pages":"Page 41"},"PeriodicalIF":0.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147417205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}