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Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique最新文献

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Éditorial
IF 0.2 4区 医学
Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique Pub Date : 2024-12-01 DOI: 10.1016/j.mednuc.2024.09.005
O.-F. Couturier , R. Abgral , C. Milin , Y. Al Tabaa
{"title":"Éditorial","authors":"O.-F. Couturier , R. Abgral , C. Milin , Y. Al Tabaa","doi":"10.1016/j.mednuc.2024.09.005","DOIUrl":"10.1016/j.mednuc.2024.09.005","url":null,"abstract":"","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"48 6","pages":"Page 225"},"PeriodicalIF":0.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Évaluation en TEP 18F-FDG de la réponse au traitement par CAR T-Cells et anticorps bispécifiques des lymphomes non hodgkiniens agressifs
IF 0.2 4区 医学
Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique Pub Date : 2024-12-01 DOI: 10.1016/j.mednuc.2024.10.007
L. Vercellino , Y. Al Tabaa , R. Di Blasi , C. Bailly
{"title":"Évaluation en TEP 18F-FDG de la réponse au traitement par CAR T-Cells et anticorps bispécifiques des lymphomes non hodgkiniens agressifs","authors":"L. Vercellino ,&nbsp;Y. Al Tabaa ,&nbsp;R. Di Blasi ,&nbsp;C. Bailly","doi":"10.1016/j.mednuc.2024.10.007","DOIUrl":"10.1016/j.mednuc.2024.10.007","url":null,"abstract":"<div><div>Refractory or relapsing aggressive non-Hodgkin lymphomas have improved prognosis in the last few years thanks to innovative therapies such as CAR T-cells and bispecific antibodies. During these therapeutic strategies, tumoral response assessment with FDG PET remains of paramount importance. However, due to their mode of action, these treatments can result in delayed responses or in inflammatory events that may hamper interpretation of metabolic imaging. Lugano criteria, relying on the Deauville score, are useful, but it is crucial to be aware of the interpretation pitfalls and to consider all the clinical and biological background of the patient, ideally in a multidisciplinary approach.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"48 6","pages":"Pages 256-262"},"PeriodicalIF":0.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Index des auteurs
IF 0.2 4区 医学
Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique Pub Date : 2024-12-01 DOI: 10.1016/S0928-1258(24)00287-0
{"title":"Index des auteurs","authors":"","doi":"10.1016/S0928-1258(24)00287-0","DOIUrl":"10.1016/S0928-1258(24)00287-0","url":null,"abstract":"","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"48 6","pages":"Pages 287-288"},"PeriodicalIF":0.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systèmes RADS en imagerie médicale
IF 0.2 4区 医学
Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique Pub Date : 2024-12-01 DOI: 10.1016/j.mednuc.2024.10.002
O.-F. Couturier , J. Reichart
{"title":"Systèmes RADS en imagerie médicale","authors":"O.-F. Couturier ,&nbsp;J. Reichart","doi":"10.1016/j.mednuc.2024.10.002","DOIUrl":"10.1016/j.mednuc.2024.10.002","url":null,"abstract":"<div><div>Reporting and Data Systems (RADS) in medical imaging are used to evaluate and classify medical images, standardize the evaluation of diagnostic images, and help clinicians to make decisions based on standardized criteria. In this review, we provide an overview of the most useful RADS systems for a good clinical practice as well as in research in nuclear medicine.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"48 6","pages":"Pages 231-240"},"PeriodicalIF":0.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Évaluation de la réponse des lymphomes en TDM : de CHESON à RECIL
IF 0.2 4区 医学
Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique Pub Date : 2024-12-01 DOI: 10.1016/j.mednuc.2024.10.001
E. de Kerviler, C. de Margerie-Mellon
{"title":"Évaluation de la réponse des lymphomes en TDM : de CHESON à RECIL","authors":"E. de Kerviler,&nbsp;C. de Margerie-Mellon","doi":"10.1016/j.mednuc.2024.10.001","DOIUrl":"10.1016/j.mednuc.2024.10.001","url":null,"abstract":"<div><div>In oncology, the use of standardized criteria to assess tumor response is crucial in clinical trials and routine care. Before 1999, criteria for malignant lymphomas were highly variable, complicating comparisons and assessment of treatment efficacy. This need for standardization to improve the reliability of results, particularly regarding normal lymph node size and how response is measured and assessed, led to the development of the Response Evaluation Criteria in Solid Tumors (RECIST) and Cheson criteria for lymphomas. The recent Response Evaluation Criteria in Lymphoma (RECIL), were specifically developed for the assessment of response to treatment in lymphomas, but these criteria are imperfect and the trend is to use the Lugano criteria instead.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"48 6","pages":"Pages 245-248"},"PeriodicalIF":0.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilan initial, facteurs pronostiques et évaluation de la réponse thérapeutique des lymphomes
IF 0.2 4区 医学
Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique Pub Date : 2024-12-01 DOI: 10.1016/j.mednuc.2024.10.008
Y. Al Tabaa , C. Bodet-Milin
{"title":"Bilan initial, facteurs pronostiques et évaluation de la réponse thérapeutique des lymphomes","authors":"Y. Al Tabaa ,&nbsp;C. Bodet-Milin","doi":"10.1016/j.mednuc.2024.10.008","DOIUrl":"10.1016/j.mednuc.2024.10.008","url":null,"abstract":"<div><div>Over the past two decades, FDG-PET has transformed the management of lymphomas, significantly enhancing staging and prognostic assessment, particularly with the adoption of the Lugano recommendations (2014). Now widely used for Hodgkin's lymphoma, DLBCL, and other FDG-avid lymphomas, PET has largely replaced the need for routine bone marrow biopsies. Intermediate PET (iPET) has proven to be a valuable tool for predicting outcomes, playing a crucial role in guiding patient stratification and treatment modifications, especially in Hodgkin's lymphoma and DLBCL. However, its early use in other types of lymphoma still requires further clinical validation. For follicular and mantle cell lymphomas, PET has shown promise in assessing treatment response, although the criteria for evaluating response need to be optimized. PET's integration into personalized treatment strategies enables more effective disease control while minimizing treatment-related toxicity.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"48 6","pages":"Pages 249-255"},"PeriodicalIF":0.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Index des mots-clés
IF 0.2 4区 医学
Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique Pub Date : 2024-12-01 DOI: 10.1016/S0928-1258(24)00288-2
{"title":"Index des mots-clés","authors":"","doi":"10.1016/S0928-1258(24)00288-2","DOIUrl":"10.1016/S0928-1258(24)00288-2","url":null,"abstract":"","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"48 6","pages":"Pages 289-292"},"PeriodicalIF":0.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Évaluation de la réponse thérapeutique en imagerie morphologique des tumeurs solides (RECIST) : historique, application et adaptation des critères aux thérapies innovantes
IF 0.2 4区 医学
Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique Pub Date : 2024-12-01 DOI: 10.1016/j.mednuc.2024.10.009
J. Dzuko Kamga , V. Tissot , R. Abgral
{"title":"Évaluation de la réponse thérapeutique en imagerie morphologique des tumeurs solides (RECIST) : historique, application et adaptation des critères aux thérapies innovantes","authors":"J. Dzuko Kamga ,&nbsp;V. Tissot ,&nbsp;R. Abgral","doi":"10.1016/j.mednuc.2024.10.009","DOIUrl":"10.1016/j.mednuc.2024.10.009","url":null,"abstract":"<div><div>The evaluation of therapeutic response in morphological imaging of solid tumors is based primarily on the RECIST criteria (Response Evaluation Criteria in Solid Tumours) established in 2000 and revised in 2009 to version RECIST 1.1. These criteria enable the efficacy of anti-cancer treatments to be analyzed on the basis of the measurement of tumor lesions by computed tomography (CT) or magnetic resonance imaging (MRI). The choice of target and non-target lesions is crucial for establishing a baseline examination prior to treatment, in order to monitor disease progression. Results are classified into 4 categories: partial response, complete response, stable disease and progressive disease. With the emergence of immunotherapy, adaptations to the criteria were necessary, leading to the creation of iRECIST in 2017, which takes into account the phenomenon of pseudoprogression. In addition, other limitations of the RECIST 1.1 criteria have been identified, notably their inability to assess functional changes in tumors, leading to the development of alternative criteria such as mRECIST and CHOI for specific types of cancer. These developments underline the importance of accurate and appropriate treatment evaluation in oncology.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"48 6","pages":"Pages 267-271"},"PeriodicalIF":0.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Les lymphomes en pratique clinique : nouveaux enjeux cliniques et thérapeutiques
IF 0.2 4区 医学
Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique Pub Date : 2024-12-01 DOI: 10.1016/j.mednuc.2024.10.004
C. Herbaux , E. Tchernonog , Y. Al Tabaa
{"title":"Les lymphomes en pratique clinique : nouveaux enjeux cliniques et thérapeutiques","authors":"C. Herbaux ,&nbsp;E. Tchernonog ,&nbsp;Y. Al Tabaa","doi":"10.1016/j.mednuc.2024.10.004","DOIUrl":"10.1016/j.mednuc.2024.10.004","url":null,"abstract":"<div><div>Lymphomas are cancers that affect the lymphatic system, where abnormal lymphocytes proliferate in tissues like lymph nodes and the spleen. The three main types are Hodgkin lymphoma (HL), aggressive high-grade non-Hodgkin lymphoma (NHL), and slower-growing low-grade NHL. HL has a high survival rate, but the focus is now on reducing long-term side effects, especially in young adults who are at risk for secondary cancers and other complications. Modern imaging, like FDG-PET scans, helps to tailor treatments more precisely. Diffuse large B-cell lymphoma (DLBCL) is one of the most common and can often be treated successfully with R-CHOP, an immunochemotherapy regimen, though relapses remain a challenge. CAR-T cell therapy is becoming a game-changer for patients who relapse or are resistant to initial treatments. Follicular lymphoma, while slower to progress, poses ongoing challenges due to frequent relapses. Current strategies are shifting towards personalized medicine, using targeted therapies like immunotherapy and CAR-T cells to improve outcomes while minimizing harmful side effects. The focus is increasingly on refining treatment approaches to balance effectiveness and quality of life for patients.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"48 6","pages":"Pages 241-244"},"PeriodicalIF":0.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Critères d’évaluation de la TEP au 18F-FDG au cours de l’immunothérapie
IF 0.2 4区 医学
Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique Pub Date : 2024-12-01 DOI: 10.1016/j.mednuc.2024.10.005
D. Hamdan , E. Anjorand , G. Bousquet , M. Soussan
{"title":"Critères d’évaluation de la TEP au 18F-FDG au cours de l’immunothérapie","authors":"D. Hamdan ,&nbsp;E. Anjorand ,&nbsp;G. Bousquet ,&nbsp;M. Soussan","doi":"10.1016/j.mednuc.2024.10.005","DOIUrl":"10.1016/j.mednuc.2024.10.005","url":null,"abstract":"<div><div>Checkpoint inhibitor therapy is well established as a first-line treatment for cancer, but assessing treatment response using molecular imaging is still evolving. Evaluating response during checkpoint inhibitor therapy is challenging due to induced immune responses and immune-related adverse effects, which lead to atypical response patterns compared to traditional chemotherapy. Positron emission tomography (PET) and its various radiotracers provide functional information that is valuable for early evaluation of treatment response and can offer critical insights into the efficacy of immunotherapy. Furthermore, PET can help differentiate between patients with a complete response and those with residual disease, potentially guiding clinicians in deciding whether to continue or escalate treatment. This review offers an overview of the application of PET in predicting and evaluating treatment response to immunotherapy, highlighting its potential to refine therapeutic strategies and improve patient outcomes.</div></div>","PeriodicalId":49841,"journal":{"name":"Medecine Nucleaire-Imagerie Fonctionnelle et Metabolique","volume":"48 6","pages":"Pages 279-286"},"PeriodicalIF":0.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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