Biometals最新文献

{"title":"Concentrations of the serum long-chain omega-3 polyunsaturated fatty acids and hair mercury in men in different apolipoprotein E phenotypes.","authors":"Unna Fagerholm, Heli E K Virtanen, Tomi-Pekka Tuomainen, Jukka T Salonen, Jyrki K Virtanen","doi":"10.1007/s10534-025-00677-7","DOIUrl":"https://doi.org/10.1007/s10534-025-00677-7","url":null,"abstract":"<p><p>Fish is a source of long-chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA) and methylmercury, a toxic heavy metal, with opposite effects on cardiovascular disease risk and cognitive decline. Besides diet, the apolipoprotein E (APOE) genotype may affect LC n-3 PUFA and mercury concentrations in the body, but the evidence is inconsistent. The subjects were 1159 men aged 42-60 years, examined in 1984-1989. ANCOVA and linear regression were used in the analyses. The mean ± SD concentrations of serum eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA) were 1.57 ± 0.82, 0.55 ± 0.10 and 2.45 ± 0.75%, respectively. There were no differences in LC n-3 PUFA concentrations between APOE4 carriers and non-carriers (P-values ≥ 0.60). The mean ± SD hair mercury concentration was 1.55 ± 1.3 µg/g. The concentrations were slightly higher in APOE4 carriers vs. non-carriers (difference 0.16 µg/g, 95% confidence interval = 0.01-0.32,P = 0.04). Overall, fish consumption was associated with higher hair mercury and serum EPA and DHA concentrations, but no differences in the associations were found between APOE4 carriers and non-carriers (P-interactions ≥ 0.30). Hair mercury, but not serum LC n-3 PUFA concentrations, were higher in APOE4 carriers vs. non-carriers. However, as no differences were found in the associations of fish intake with LC n-3 PUFA and mercury concentrations, the results could be due to differences in mercury accumulation.</p>","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In memoriam: Carl J. Carrano : July 14, 1950-January 26, 2022.","authors":"Frithjof C Küpper, Eleanor Carrano, Kenneth N Raymond, Eric Miller, Ricardo Cruz-López, Ana Mijovilovich, Kyoko Yarimizu, Andrew Cooksy, Wes Harris, Shady A Amin, Alison Butler, John C Carrano","doi":"10.1007/s10534-024-00651-9","DOIUrl":"https://doi.org/10.1007/s10534-024-00651-9","url":null,"abstract":"<p><p>This article is a celebration of the life and work of Carl J. Carrano who, from a childhood in Long Island, New York, built a career in bioinorganic chemistry, especially in the context of metal uptake and halogen metabolism in microbes and marine organisms.</p>","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accumulation of heavy metals in the mycelium of Abortiporus biennis and their effect on oxalate oxidase activity","authors":"Marcin Grąz,&nbsp;Anna Jarosz-Wilkołazka,&nbsp;Jolanta Polak,&nbsp;Bożena Pawlikowska-Pawlęga,&nbsp;Justyna Kapral-Piotrowska,&nbsp;Wioleta Ciempiel,&nbsp;Marta Ruminowicz-Stefaniuk","doi":"10.1007/s10534-025-00675-9","DOIUrl":"10.1007/s10534-025-00675-9","url":null,"abstract":"<div><p><i>Abortiporus biennis</i> belongs to a basidiomycete fungi with the unique ability to degrade oxalate using enzyme oxalate oxidase. Oxalate oxidase (OXO) from <i>Abortiporus biennis</i> is an intracellular oxalic acid-induced enzyme, which catalyses the degradation of oxalic acid to carbon dioxide and hydrogen peroxide. OXO activity was stimulated by all the heavy metals tested (copper, manganese, lead and cadmium) after addition as water-soluble salts to <i>A. biennis</i> fungal cultures. Manganese ions stimulated OXO activity to the greatest extent among the tested metal ions. In the presence of manganese ions, an elevated concentration of oxalate was also detected in the fungal culture after 7 days of cultivation. The manganese, lead, and cadmium ions were accumulated by the <i>A. biennis</i> mycelium. Among them, lead was accumulated to a great extent. It was observed that the accumulation of lead ions occurred in the vicinity of the <i>A.</i> <i>biennis</i> hyphal cell wall.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"38 2","pages":"699 - 710"},"PeriodicalIF":4.1,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143582145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antidiabetic potential of vanadium complexes combined with olive leaf extracts: a viable approach to reduce metal toxicity","authors":"Daniele Sanna,&nbsp;Angela Fadda,&nbsp;Milena Casula,&nbsp;Grazia Palomba,&nbsp;Maria Cristina Sini,&nbsp;Maria Colombino,&nbsp;Carla Rozzo,&nbsp;Giuseppe Palmieri,&nbsp;Carmela Gallo,&nbsp;Dalila Carbone,&nbsp;Laura Siracusa,&nbsp;Luana Pulvirenti,&nbsp;Valeria Ugone","doi":"10.1007/s10534-025-00673-x","DOIUrl":"10.1007/s10534-025-00673-x","url":null,"abstract":"<div><p>Vanadium compounds are known for their antidiabetic properties due to their ability to interfere with numerous mechanisms that lead to the decrease of blood glucose levels. Although some of these compounds have reached clinical trials and have the advantage of being orally administrable, no vanadium-containing drugs are currently available on the market, primarily due to the high doses required, which can lead intestinal and renal problems in case of long-term treatments. In this study, plant extracts obtained from olive leaves (<i>Olea europaea</i> L.) were combined with vanadium complexes with established antidiabetic activity with the aim of reducing their metal toxicity and, at the same time, amplifying their hypoglycemic action. The extracts were characterized by chromatographic and spectroscopic methods showing a composition rich in polyphenols and a high antioxidant activity. Formulations containing a vanadium complex (bis(maltolato)oxidovanadium(IV), BMOV, or bis(picolinato)oxidovanadium(IV), BPOV) mixed with different amount of olive leaves extract were tested in vitro to evaluate intestinal toxicity and hypoglycemic activity. The results demonstrated that the plant extracts are generally non-toxic toward human colon fibroblast in the whole range of tested concentrations and some of them are particularly effective in reducing the toxicity of the two vanadium compounds. Further in vitro tests conducted on differentiated human adipocyte cell lines revealed a significant increase in glucose uptake following treatment with the mixed formulations, compared to the effect of the individual components, indicating a synergistic effect. Immunocytochemical assays suggested that the translocation of GLUT4 transporter can be involved in the mechanism of action.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"38 2","pages":"683 - 698"},"PeriodicalIF":4.1,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10534-025-00673-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of potential antiparasitic effect of ZnO nanoparticles on experimental cryptosporidiosis in immunosuppressed mice","authors":"Salhah Hamed Alrefaee,&nbsp;Faizah S. Aljohani,&nbsp;M. El-khatib,&nbsp;Yahya H. Shahin,&nbsp;Bassma H. Elwakil,&nbsp;Sendianah H. Shahin,&nbsp;Sara H. Akl,&nbsp;Esraa Abdelhamid Moneer,&nbsp;Amira Abd-elfattah Darwish","doi":"10.1007/s10534-025-00669-7","DOIUrl":"10.1007/s10534-025-00669-7","url":null,"abstract":"<div><p><i>Cryptosporidium</i> is a food and water-borne enteric protozoan that infects a wide range of vertebrates, causing life-threatening complications, particularly in immunocompromised hosts. The absence of effective anti-cryptosporidial medications could be attributed to the parasite’s specific intestinal location, as well as the lack of research into the mechanism by which the protozoan impairs intestine cellular function. The present work aimed to evaluate the in vivo efficacy of zinc nanoparticles in the treatment of experimental cryptosporidiosis infection in immunosuppressed mice. Small-sized ZnO-NPs revealed better treatment efficacy than Large-sized ZnO-NPs in all studies. Nitazoxanide-treated group revealed the highest percentage reduction of the oocyst’s counts followed by the small-sized ZnO-NPs treated group. The small-sized ZnO-NPs treated mice group showed a minimal inflammatory effect in all examined treated tissues when compared to the infected non-treated group. The morphological structure of the oocysts was examined using SEM indicating variable degrees of morphological changes in the treated mice. Moreover, the levels of biochemical analyses were significantly lower in the treated group. The histopathological study revealed the significant effect of small-sized ZnO-NPs in treating cryptosporidiosis.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"38 2","pages":"647 - 661"},"PeriodicalIF":4.1,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143497570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unravelling the developmental toxicity of heavy metals using zebrafish as a model: a narrative review","authors":"Sanjib Manna,&nbsp;Sayed Mohammed Firdous","doi":"10.1007/s10534-025-00671-z","DOIUrl":"10.1007/s10534-025-00671-z","url":null,"abstract":"<div><p>Developmental toxicity is the disruption of an organism’s normal development which may occur in either the parent before conception or in the growing creature itself. Zebrafish (<i>Danio rerio</i>) are being employed as effective vertebrate models to evaluate the safety and toxicity of chemicals because they can breed multiple times in a year so we can observe the toxic effects in the next generation and their development mental stages can be observed and define clearly because their 1 cell stage to prime stage is transparent so we can observe the development of every organ also they have nearly about 80% genetic similarity with humans and shares the similar neuromodulatory structure along with multiple neurotransmitter. The recent research endeavours to examine the harmful outcome of various heavy metals such as cadmium, chromium, nickel, arsenic, lead, mercury, bismuth, iron, manganese, and thallium along with microplastics on zebrafish embryos when subjected to environmentally acceptable levels of every single metal in addition to co-exposure at various points in time. These heavy metals can alter the mRNA expression levels, increase the reactive oxygen species (ROS) generation, decrease antioxidant expression, damage neuronal function, alter neurotransmitter release, alter the expression of several apoptotic proteins, interfere with the different signalling pathways, decrease heat rates, increase malformations like – pericardial oedema, heart oedema, reduce in length tail bending abnormal formation in fins. Thereafter we concluded that due to its involvement in the food chain, it also causes severe effects on human beings.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"38 2","pages":"419 - 463"},"PeriodicalIF":4.1,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of hydrogel loading with curcumin and silver nanoparticles: biocompatibilities and anti-biofilm activities","authors":"Wei Qing Hong,&nbsp;Wing-Hin Lee,&nbsp;Siti Hajar Musa,&nbsp;Nur Azzalia Kamaruzaman,&nbsp;Ching-Yee Loo","doi":"10.1007/s10534-025-00670-0","DOIUrl":"10.1007/s10534-025-00670-0","url":null,"abstract":"<div><p>Chronic wound healing is associated with prolonged elevated inflammation and high levels of oxidative stress leading to cell death. The majority of wounds are colonized with antibiotic-resistant bacterial biofilms such as <i>Pseudomonas aeruginosa</i> and <i>Staphylococcus aureus</i>. An ideal wound treatment should include agents with antioxidant, anti-inflammatory, and antibiofilm behavior. Therefore, in this study, a combination of curcumin nanoparticle (Cur-NP) and silver nanoparticle (AgNP) (Cur-NP/AgNP) loaded PVA hydrogel was used to inhibit the bacterial attachment and subsequent biofilm formation of <i>P. aeruginosa</i> and <i>S. aureus</i>. Cur was known for its antioxidant and anti-inflammatory effect while being non-toxic to cells. Meanwhile, AgNP demonstrated superior anti-bacterial and antibiofilm activities against both <i>P. aeruginosa</i> and <i>S. aureus</i>. Cur-NP/AgNP loaded PVA hydrogels completely inhibited the bacterial attachment and biofilm formation, possibly due to synergistic effect of Cur-NPs and AgNPs in killing the bacterial cells. It should be highlighted that no surviving bacterial cells were noted for Cur-NP/AgNP loaded hydrogels. On the other hand, AgNPs or Cur-NPs alone loaded hydrogels were unable to achieve complete inhibition of biofilm formation, even though significant reduction in the biofilm mass was noted compared with control samples. Cur-NP and AgNP exerted oxidative-stress induced cell death in HaCaT cells via mitochondrial dysfunction, mitochondrial membrane potential (MMP) reduction, adenosine triphosphate inhibition, and increased cytochrome C release. The toxicity of formulation followed the decreasing trend: Cur-NP/AgNP &lt; AgNPs alone &lt; Cur-NPs alone. Taken together, the combination of Cur-NP/AgNP completely inhibited bacterial biofilm formation through bactericidal effect on the planktonic cells while exerted the least toxic effects towards skin cells.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"38 2","pages":"663 - 682"},"PeriodicalIF":4.1,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Taurine decreases arsenic and microplastic toxicity in broccoli (Brassica oleracea L.) through functional and microstructural alterations","authors":"Shahar Yar,&nbsp;Muhammad Arslan Ashraf,&nbsp;Rizwan Rasheed,&nbsp;Umer Farooq,&nbsp;Arslan Hafeez,&nbsp;Shafaqat Ali,&nbsp;Mudassar Shahid,&nbsp;Pallab K. Sarker","doi":"10.1007/s10534-025-00667-9","DOIUrl":"10.1007/s10534-025-00667-9","url":null,"abstract":"<div><p>Contamination of vegetables with heavy metals and microplastics is a major environmental and human health concern. This study investigated the role of taurine (TAE) in alleviating arsenic (As) and polyvinyl chloride microplastic (MP) toxicity in broccoli plants. The experiment followed a completely randomized design with four replicates per treatment. Plants were grown in soil spiked with MP (200 mg kg^‒1), As (42.8 mg kg^‒1), and their combination (As + MP) with or without taurine (TAE; 100 mg L^‒1) foliar supplementation. Results demonstrated that MP, As, and As + MP toxicity markedly decreased growth, chlorophyll content, photosynthesis, and nutrient uptake in broccoli plants. Exposure to individual or combined MP and As increased oxidative damage, indicated by elevated methylglyoxal (MG), superoxide radical (O₂^⋅‒), hydrogen peroxide (H₂O₂), hydroxyl radical (⋅OH), and malondialdehyde (MDA) levels alongside intensified lipoxygenase (LOX) activity and leaf relative membrane permeability (RMP). Histochemical analyses revealed higher lipid peroxidation, membrane damage as well as increased H₂O₂ and O₂^•‒ levels in the leaves of stressed plants. Micropalstic and As toxicity deteriorated anatomical structures, with diminished leaf and root epidermal thickness, cortex thickness, and vascular bundle area. However, TAE improved the antioxidant enzyme activities, endogenous ascorbate–glutathione pools, hydrogen sulfide and nitric oxide levels that reduced H₂O₂, O₂^⋅‒, ⋅OH, RMP, MDA, and activity of LOX. Taurine elevated osmolyte accumulation that protected membrane integrity, resulting in increased leaf relative water content and plant biomass. Plants supplemented with TAE demonstrated improved anatomical structures, resulting in diminished As uptake and its associated phytotoxicity. These findings highlight that TAE improved redox balance, osmoregulation, ion homeostasis, and anatomical structures, augmenting tolerance to As and MP toxicity in broccoli.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"38 2","pages":"597 - 621"},"PeriodicalIF":4.1,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heavy metal-induced disruption of the autophagy-lysosomal pathway: implications for aging and neurodegenerative disorders","authors":"Shrabani Das,&nbsp;Lokesh Murumulla,&nbsp;Pritha Ghosh,&nbsp;Suresh Challa","doi":"10.1007/s10534-025-00665-x","DOIUrl":"10.1007/s10534-025-00665-x","url":null,"abstract":"<div><p>Heavy metals such as lead, mercury, cadmium, magnesium, manganese, arsenic, copper pose considerable threats to neuronal health and are increasingly recognized as factors contributing to aging-related neurodegeneration. Exposure to these environmental toxins disrupts cellular homeostasis, resulting in oxidative stress and compromising critical cellular processes, particularly the autophagy-lysosomal pathway. This pathway is vital for preserving cellular integrity by breaking down damaged proteins and organelles; however, toxicity from heavy metals can hinder this function, leading to the buildup of harmful substances, inflammation, and increased neuronal injury. As individuals age, the consequences of neurodegeneration become more significant, raising the likelihood of developing disorders like Alzheimer’s and Parkinson’s disease. This review explores the intricate relationship between heavy metal exposure, dysfunction of the autophagy-lysosomal pathway, and aging-related neurodegeneration, emphasizing the urgent need for a comprehensive understanding of these mechanisms. The insights gained from this analysis are crucial for creating targeted therapeutic approaches aimed at alleviating the harmful effects of heavy metals on neuronal health and improving cellular resilience in aging populations.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"38 2","pages":"371 - 417"},"PeriodicalIF":4.1,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of short term dietary zinc deficiency and zinc supplementation on nitro-oxidative stress in testes of Wistar rats","authors":"Deepa Kumari,&nbsp;Neena Nair,&nbsp;R. S. Bedwal","doi":"10.1007/s10534-025-00666-w","DOIUrl":"10.1007/s10534-025-00666-w","url":null,"abstract":"<div><p>Zinc is crucial for several cellular functions in the biological system. Zinc insufficiency is one of the most prevalent types of micronutrient malnutrition in the world. Present study was conducted to detect testicular free radical levels i.e. lipid peroxidation (LPO), hydroperoxides, hydroxyl radical (OH^<b>.</b>), nitric oxide (NO) and peroxynitrite (ONOO⁻) after short term dietary zinc deficiency and zinc supplementation. Pre-pubertal rats (n = 144) were divided into two groups with 6 sub-groups viz. zinc control (ZC, 100 µg/g zinc diet), pair-fed (PF, 100 µg/g zinc diet), zinc deficient (ZD, &lt; 1.00 µg/g), zinc control supplementation (ZCS, 100 µg/g zinc diet), pair-fed supplementation (PFS, 100 µg/g zinc diet) and zinc deficient supplementation (ZDS, 100 µg/g zinc diet). Experiments were set for 2- and 4-weeks followed by 4 weeks of dietary zinc supplementation. Zinc deficient groups (2- and 4-weeks) exhibited significant (p &lt; 0.05) increase in testicular LPO (TBARS), hydroperoxides, OH^·, NO and ONOO⁻ levels as compared to their respective control and pair-fed groups. Zinc deficient supplementation group (2ZDS) revealed a non-significant increase in OH^·, NO and ONOO⁻ levels while a significant increase in LPO and hydroperoxides levels. 4ZDS group showed a significant increase in the free radical levels, however the increase was less as compared to 4ZD group. Dietary zinc deficiency results in induction of cellular lipoperoxidation as well as causes stimulation of nitro-oxidative stress. Zinc supplementation (although for short duration signifying zinc redistribution in the testicular tissue) indicated positive response accounting for reduced free radical generation and also implicating its requirement in optimum level for sustentation of reproductive functions.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"38 2","pages":"587 - 596"},"PeriodicalIF":4.1,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143389757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}