Biometals最新文献

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Novel native probiotics with protective effects against nickel-induced kidney injury: a strategy for heavy metal toxicity. 具有保护镍肾损伤作用的新型天然益生菌:重金属中毒的一种策略。
IF 4.1 3区 生物学
Biometals Pub Date : 2025-04-05 DOI: 10.1007/s10534-025-00681-x
Shokufeh Beglari, Niloofar Rezaie, Fatemeh Haririzadeh Jouriani, Elham Haj Agha Gholizadeh Khiavi, Shadi Aghamohammad, Mahdi Rohani
{"title":"Novel native probiotics with protective effects against nickel-induced kidney injury: a strategy for heavy metal toxicity.","authors":"Shokufeh Beglari, Niloofar Rezaie, Fatemeh Haririzadeh Jouriani, Elham Haj Agha Gholizadeh Khiavi, Shadi Aghamohammad, Mahdi Rohani","doi":"10.1007/s10534-025-00681-x","DOIUrl":"https://doi.org/10.1007/s10534-025-00681-x","url":null,"abstract":"<p><p>Recent studies have shown that exposure to heavy metals, particularly Nickel, and exacerbates kidney diseases by increasing oxidative stress. Probiotics, recognized for their antioxidant properties, may provide a beneficial approach to mitigate this oxidative damage. This research aims to explore the efficacy of native probiotics in reducing oxidative stress in kidney tissues, potentially leading to improved protective strategies against the toxicity caused by heavy metals. In this study, forty male NMRI mice were exposed to Nickel to induce oxidative stress, followed by probiotic treatment to evaluate its potential protective effects. The impact of these interventions on the antioxidant system was assessed through Real-Time PCR analysis, which measured gene expression profiles in the kidney tissue of the mice. The study demonstrated that native probiotic strains effectively upregulated the expression of genes related to Nrf2 signaling pathway before exposing to oxidant agents. Despite the suppressive effects of Nickel exposure on these gene expressions, the subsequent administration of probiotics after Nickel resulted in a significant increase and enhancement of expression levels. This research underscores the detrimental effects of Nickel, a heavy metal, on kidney health while exploring the protective properties of probiotics, particularly their anti-oxidative effects. Given the substantial risks linked to heavy metal exposure, the integration of probiotics presents a promising strategy to alleviate oxidative stress, thereby potentially preventing various kidney disorders associated with this condition. The findings advocate for a dual approach of addressing heavy metal toxicity and enhancing kidney resilience through probiotic intervention.</p>","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of antifungal and antibiofilm activities of green synthesized silver nanoparticles against Candida glabrata. 绿色合成纳米银对光假丝酵母的抗真菌和抗膜活性研究。
IF 4.1 3区 生物学
Biometals Pub Date : 2025-04-04 DOI: 10.1007/s10534-025-00680-y
Irshad Ahamad, Tasneem Fatma
{"title":"Investigation of antifungal and antibiofilm activities of green synthesized silver nanoparticles against Candida glabrata.","authors":"Irshad Ahamad, Tasneem Fatma","doi":"10.1007/s10534-025-00680-y","DOIUrl":"https://doi.org/10.1007/s10534-025-00680-y","url":null,"abstract":"<p><p>Candida glabrata is an important human fungal pathogen known to cause life-threatening infections in people with impaired immune systems. In the mouth cavities, trachea, and catheters, Candida glabrata biofilm grows unhindered and is the primary etiological factor in the pathophysiology of candidiasis, in the worst cases, this leads to systemic infections. Therefore, developing novel biofilm preventative and therapeutic agents is urgently required. Here, in the present study, an effort was made to monitor the function of silver nanoparticles (AgNPs) generated from a cyanobacterium (Anabaena variabilis) as a novel antibiofilm agent focusing on candidiasis. Anabaena variabilis cell extract was used to synthesize AgNPs, characterized by UV-visible spectroscopy. The minimum inhibitory concentration (MIC) of AgNPs was observed at 25 µg/mL in Candida glabrata. At the concentration of 2MIC of AgNPs (50 µg/mL), 67 ± 0.84% membrane permeability was noticed at the same concentration the viable cells were found at only 2.8 ± 2.0%; while in the early phase of apoptosis, were found at 15.5 ± 1.5%; and in the late phase of apoptosis, were found at 81.8 ± 4.2%, thus confirming the cell's death. Additionally, a cell-cycle study also declared the halted cycle in the S phase by increasing the number of cells. The growth inhibition assay shows that the test organism's growth steadily decreased in comparison to the control with increasing AgNPs concentrations. Additionally, in the scanning electron microscopic pictures of Candida glabrata treated with AgNPs, which exhibited deep wrinkles and deformity, confirming the cells death. At the concentrations of 2MIC of AgNPs (50 µg/mL) showed 72 ± 0.86% of biofilm inhibition and 80 ± 1.3% degradation during the biofilm study. In conclusion, all results demonstrate that AgNPs have great antifungal potential; therefore, AgNPs could be used to control biofilm produced by emerging multidrug-resistant Candida glabrata.</p>","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative evaluation of biologically and chemically synthesized zinc oxide nanoparticles for preventing Candida auris biofilm. 生物合成和化学合成氧化锌纳米颗粒预防耳念珠菌生物膜的比较评价。
IF 4.1 3区 生物学
Biometals Pub Date : 2025-03-31 DOI: 10.1007/s10534-025-00678-6
Bahgat Fayed, Hoda S El-Sayed, Shanshan Luo, Aisha E Reda
{"title":"Comparative evaluation of biologically and chemically synthesized zinc oxide nanoparticles for preventing Candida auris biofilm.","authors":"Bahgat Fayed, Hoda S El-Sayed, Shanshan Luo, Aisha E Reda","doi":"10.1007/s10534-025-00678-6","DOIUrl":"https://doi.org/10.1007/s10534-025-00678-6","url":null,"abstract":"<p><p>Candidozyma auris (formerly Candida auris) is a multidrug-resistant yeast that poses a significant global health threat due to its ability to form biofilms and resist various antifungal treatments. This study evaluates and compares the antifungal efficacy of biologically synthesized zinc oxide nanoparticles (ZnO-NP-B) and chemically synthesized ZnO nanoparticles (ZnO-NP-C1 and ZnO-NP-C2), developed using the dry-wet chemical method and sol-gel method, respectively. ZnO-NP-B was synthesized using Lactobacillus gasseri. The nanoparticles were characterized for size, charge, and morphology using Particle Size Analyzer, photon correlation spectroscopy with a 90 Plus Zetasizer, and scanning electron microscopy (SEM), respectively. The antifungal activity was assessed through minimum inhibitory concentration (MIC<sub>50</sub>) determination, biofilm inhibition assays by XTT assay, and gene expression analysis. ZnO-NP-C1 exhibited the highest antifungal activity against C. auris planktonic cells, with a MIC<sub>50</sub> value of 61.9 ± 3.3 µg/ml, followed by ZnO-NP-C2 (151 ± 7.83 µg/ml), whereas ZnO-NP-B showed limited efficacy (MIC<sub>50</sub> = 1 mg/ml). Chemically synthesized ZnO-NPs, particularly ZnO-NP-C2, did not induce overexpression of resistance genes (CDR1, MDR1, ERG2, ERG11, FKS1, CHS1), whereas ZnO-NP-B triggered their upregulation, potentially promoting resistance. ZnO-NP-C1 was the most effective in preventing biofilm formation, reducing C. auris adhesion by 67.9 ± 2.35% at 150 µg/ml, while ZnO-NP-B exhibited negligible inhibition. Gene expression analysis further confirmed that ZnO-NP-C1 significantly downregulated adhesive genes (ALS5, IFF4, CSA1) by up to 0.37 ± 0.006, 0.043 ± 0.002, and 0.06 ± 0.0004, respectively. These findings highlight the potential of ZnO-NP-C1 as a promising antifungal agent for preventing C. auris biofilms, emphasizing the critical role of synthesis methods in optimizing nanoparticle properties for antifungal applications.</p>","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trace elements and cognitions in elderly population: a case-control study. 老年人微量元素与认知:一项病例对照研究。
IF 4.1 3区 生物学
Biometals Pub Date : 2025-03-26 DOI: 10.1007/s10534-025-00679-5
Anil Kumar Maurya, Mona Srivastava, Ashish Ashish, Nitish Kumar Singh, Abhay Kumar Yadav, Shani Vishwakarma, Royana Singh
{"title":"Trace elements and cognitions in elderly population: a case-control study.","authors":"Anil Kumar Maurya, Mona Srivastava, Ashish Ashish, Nitish Kumar Singh, Abhay Kumar Yadav, Shani Vishwakarma, Royana Singh","doi":"10.1007/s10534-025-00679-5","DOIUrl":"https://doi.org/10.1007/s10534-025-00679-5","url":null,"abstract":"<p><p>There have been almost no studies with trace elements and psychological battery in cognitively impaired elderly individuals. Such research is crucial to enhance diagnostic accuracy. We aim to identify significant differences in blood serum concentration levels of trace elements, Hindi Mini-Mental State Examination (HMMSE), and psychological battery as Hindi Mattis Dementia Rating Scale (HMDRS) scores between case and control groups in the elderly. A cross-sectional research design was conducted with a total of 240 subjects, comprising 120 each from the case and control groups. Trace elements were analyzed using Atomic Absorption Spectrometry. HMMSE and HMDRS tests were administered to assess cognition scores. The chi-square test, t-test, and appropriate statistics were utilized. Our findings indicate significant differences in demographic factors (age, gender, education level) and clinical levels (p < .001), while caste, habitat, and marital status were not significant (p < .05). Concentration levels of Iron (Fe) and Copper (Cu) was higher, Zinc (Zn), Chromium (Cr), and Selenium (Se) were lower, significantly different (p < .001), but Magnesium (Mg) was not (p < .05). Additionally, third HMMSE and HMDRS were significant (p < .001) between the case and control groups in the elderly. The study suggested that higher levels of Fe and Cu, while lower Zn, Cr, and Se blood serum concentrations increased the risk of cognitive impairments in the elderly population, demonstrated by the HMMSE and HMDRS test scores which were lower in the case group.</p>","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anticancer potential of lactoferrin: effects, drug synergy and molecular interactions 乳铁蛋白的抗癌潜力:作用、药物协同作用和分子相互作用。
IF 4.1 3区 生物学
Biometals Pub Date : 2025-03-21 DOI: 10.1007/s10534-025-00672-y
D. B. León-Flores, L. I. Siañez-Estada, B. F. Iglesias-Figueroa, T. S. Siqueiros-Cendón, E. A. Espinoza-Sánchez, A. Varela-Ramírez, R. J. Aguilera, Q. Rascón-Cruz
{"title":"Anticancer potential of lactoferrin: effects, drug synergy and molecular interactions","authors":"D. B. León-Flores,&nbsp;L. I. Siañez-Estada,&nbsp;B. F. Iglesias-Figueroa,&nbsp;T. S. Siqueiros-Cendón,&nbsp;E. A. Espinoza-Sánchez,&nbsp;A. Varela-Ramírez,&nbsp;R. J. Aguilera,&nbsp;Q. Rascón-Cruz","doi":"10.1007/s10534-025-00672-y","DOIUrl":"10.1007/s10534-025-00672-y","url":null,"abstract":"<div><p>Cancer treatment is among today’s most active and challenging research fields. In recent years, significant progress has been made in developing new cancer therapies, including nutraceuticals and natural compounds with anticancer properties. Lactoferrin, a glycoprotein present in mammals, is of significant interest due to its pleiotropic behavior, demonstrating a broad spectrum of biological activities such as antimicrobial, antioxidant, anti-inflammatory, immunomodulatory, and anticancer effects. In this review, we examine the current knowledge of Lf's role in cancer. In addition, it exhibits a synergistic effect along with conventional drugs, potentially enhancing their efficacy and, at the same time, reducing the side effects associated with most traditional therapies. However, it is essential to consider the precise molecular mechanism by which Lf exerts its antitumor activity. Searching interactions with several molecules can provide insight into this mechanism. Additionally, finding lactoferrin receptors can improve the strategies for the specific release of the conjugates. For all these reasons, Lactoferrin becomes a potential therapeutic agent that should be examined in depth.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"38 2","pages":"465 - 484"},"PeriodicalIF":4.1,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Apoptotic cell death induced by copper (II), manganese (II) and silver (I) complexes containing bridging dicarboxylate and 1,10-phenanthroline ligands: one of the multi-modes of anticancer activity? 含桥接二羧酸盐和1,10-菲罗啉配体的铜(II)、锰(II)和银(I)配合物诱导的凋亡细胞死亡:抗癌活性的多模式之一?
IF 4.1 3区 生物学
Biometals Pub Date : 2025-03-17 DOI: 10.1007/s10534-025-00676-8
Ella O'Sullivan, Denis O'Shea, Michael Devereux, Orla Howe
{"title":"Apoptotic cell death induced by copper (II), manganese (II) and silver (I) complexes containing bridging dicarboxylate and 1,10-phenanthroline ligands: one of the multi-modes of anticancer activity?","authors":"Ella O'Sullivan, Denis O'Shea, Michael Devereux, Orla Howe","doi":"10.1007/s10534-025-00676-8","DOIUrl":"https://doi.org/10.1007/s10534-025-00676-8","url":null,"abstract":"<p><p>Cu(II), Mn(II) and Ag(I) complexes incorporating bridging dicarboxylate and 1,10-phenanthroline ligands have exhibited anti-cancer potential with significant in vitro and in vivo cytotoxic efficacies. Our study focuses on regulated cell death process of apoptosis as a mode of action of the anti-cancer activity by the complexes. Cytotoxicity screening of the complexes demonstrated all the metal-dicarboxylate-phenanthroline complexes exhibit superior activity compared to their non-phenanthroline containing precursors, in addition to cisplatin. The Cu(II) and Mn(II) complexes were shown to induce reactive oxygen species (ROS) but this was not observed for the Ag(I) analogues. Furthermore, apoptosis was found to be induced by all the metal-phenanthroline complexes to varying degrees contingent on the type of metal centre in the complex. Apoptotic gene expression analysis established the predominant activation of the intrinsic apoptotic pathway, with co-stimulation of the extrinsic pathway observed in some cases. The mechanistic data provided within this study highlights the multi-modal activity of the metal-phenanthroline complexes contingent on the type of metal present, warranting continued investigation of their biological modes of action beyond apoptosis induction.</p>","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sustained release of Sr and Ca from a micronanotopographic titanium surface improves osteoblast function 从微纳钛表面持续释放硒和钙可改善成骨细胞功能。
IF 4.1 3区 生物学
Biometals Pub Date : 2025-03-17 DOI: 10.1007/s10534-025-00668-8
Luan Viana Faria, Maria Eduarda Scordamaia Lopes, Diego Pedreira de Oliveira, Fernando Santos da Silva, Cecilio Sadao Fugivara, Andressa Vilas Boas Nogueira, James Deschner, Joni Augusto Cirelli
{"title":"Sustained release of Sr and Ca from a micronanotopographic titanium surface improves osteoblast function","authors":"Luan Viana Faria,&nbsp;Maria Eduarda Scordamaia Lopes,&nbsp;Diego Pedreira de Oliveira,&nbsp;Fernando Santos da Silva,&nbsp;Cecilio Sadao Fugivara,&nbsp;Andressa Vilas Boas Nogueira,&nbsp;James Deschner,&nbsp;Joni Augusto Cirelli","doi":"10.1007/s10534-025-00668-8","DOIUrl":"10.1007/s10534-025-00668-8","url":null,"abstract":"<div><p>The surface chemistry and topographical features of dental implants play a crucial role in influencing the osseointegration process. Alkaline earth elements such as strontium (Sr) and calcium (Ca) exert beneficial effects in promoting bone formation. This study aimed to evaluate micronanotopographic cpTi substrates that doped these elements, Sr and Ca. The composition and morphology were analyzed by X-ray photoelectron spectroscopy, scanning electron microscopy (SEM), and atomic force microscopy (AFM). Wettability assays, Sr and Ca release tests, and electrochemical behavior were also conducted. Proliferation, adhesion, and differentiation of MC3T3-E1 cells on this surface were evaluated in vitro. Direct fluorescence assays and SEM, cell viability, alkaline phosphatase (ALP) activity, and mineralization nodule formation were performed. The biological results showed the absence of cytotoxicity after the treatments, increased cell spreading on the micronanotopographic substrates, and greater mineralization nodule formation on surfaces doped with Sr and Sr/Ca. Gene and protein expression of osteoblastic markers were assessed through PCR and ELISA, and some genes were regulated on the doped surfaces at three and seven days of cell culture, like <i>Bglap</i><i>, </i><i>Ibsp</i><i>, </i><i>Spp, Col1a1,</i> and <i>Runx2</i>. The micronanotopographic substrates modified the physicochemical properties and morphology of the pre-osteoblasts. The results indicate that the biological effect of implants treated with Sr and Sr/Ca was significantly superior to that of polished surfaces and undoped micronanotopographic implants. Furthermore, the addition of Sr alone was sufficient to improve events related to osseointegration.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"38 2","pages":"623 - 646"},"PeriodicalIF":4.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concentrations of the serum long-chain omega-3 polyunsaturated fatty acids and hair mercury in men in different apolipoprotein E phenotypes. 不同载脂蛋白 E 表型的男性血清长链欧米伽-3 多不饱和脂肪酸浓度和头发汞含量。
IF 4.1 3区 生物学
Biometals Pub Date : 2025-03-14 DOI: 10.1007/s10534-025-00677-7
Unna Fagerholm, Heli E K Virtanen, Tomi-Pekka Tuomainen, Jukka T Salonen, Jyrki K Virtanen
{"title":"Concentrations of the serum long-chain omega-3 polyunsaturated fatty acids and hair mercury in men in different apolipoprotein E phenotypes.","authors":"Unna Fagerholm, Heli E K Virtanen, Tomi-Pekka Tuomainen, Jukka T Salonen, Jyrki K Virtanen","doi":"10.1007/s10534-025-00677-7","DOIUrl":"https://doi.org/10.1007/s10534-025-00677-7","url":null,"abstract":"<p><p>Fish is a source of long-chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA) and methylmercury, a toxic heavy metal, with opposite effects on cardiovascular disease risk and cognitive decline. Besides diet, the apolipoprotein E (APOE) genotype may affect LC n-3 PUFA and mercury concentrations in the body, but the evidence is inconsistent. The subjects were 1159 men aged 42-60 years, examined in 1984-1989. ANCOVA and linear regression were used in the analyses. The mean ± SD concentrations of serum eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA) were 1.57 ± 0.82, 0.55 ± 0.10 and 2.45 ± 0.75%, respectively. There were no differences in LC n-3 PUFA concentrations between APOE4 carriers and non-carriers (P-values ≥ 0.60). The mean ± SD hair mercury concentration was 1.55 ± 1.3 µg/g. The concentrations were slightly higher in APOE4 carriers vs. non-carriers (difference 0.16 µg/g, 95% confidence interval = 0.01-0.32,P = 0.04). Overall, fish consumption was associated with higher hair mercury and serum EPA and DHA concentrations, but no differences in the associations were found between APOE4 carriers and non-carriers (P-interactions ≥ 0.30). Hair mercury, but not serum LC n-3 PUFA concentrations, were higher in APOE4 carriers vs. non-carriers. However, as no differences were found in the associations of fish intake with LC n-3 PUFA and mercury concentrations, the results could be due to differences in mercury accumulation.</p>","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In memoriam: Carl J. Carrano : July 14, 1950-January 26, 2022. 纪念:卡尔·j·卡拉诺:1950年7月14日- 2022年1月26日。
IF 4.1 3区 生物学
Biometals Pub Date : 2025-03-12 DOI: 10.1007/s10534-024-00651-9
Frithjof C Küpper, Eleanor Carrano, Kenneth N Raymond, Eric Miller, Ricardo Cruz-López, Ana Mijovilovich, Kyoko Yarimizu, Andrew Cooksy, Wes Harris, Shady A Amin, Alison Butler, John C Carrano
{"title":"In memoriam: Carl J. Carrano : July 14, 1950-January 26, 2022.","authors":"Frithjof C Küpper, Eleanor Carrano, Kenneth N Raymond, Eric Miller, Ricardo Cruz-López, Ana Mijovilovich, Kyoko Yarimizu, Andrew Cooksy, Wes Harris, Shady A Amin, Alison Butler, John C Carrano","doi":"10.1007/s10534-024-00651-9","DOIUrl":"https://doi.org/10.1007/s10534-024-00651-9","url":null,"abstract":"<p><p>This article is a celebration of the life and work of Carl J. Carrano who, from a childhood in Long Island, New York, built a career in bioinorganic chemistry, especially in the context of metal uptake and halogen metabolism in microbes and marine organisms.</p>","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accumulation of heavy metals in the mycelium of Abortiporus biennis and their effect on oxalate oxidase activity 双生Abortiporus biennis菌丝中重金属的积累及其对草酸氧化酶活性的影响。
IF 4.1 3区 生物学
Biometals Pub Date : 2025-03-08 DOI: 10.1007/s10534-025-00675-9
Marcin Grąz, Anna Jarosz-Wilkołazka, Jolanta Polak, Bożena Pawlikowska-Pawlęga, Justyna Kapral-Piotrowska, Wioleta Ciempiel, Marta Ruminowicz-Stefaniuk
{"title":"Accumulation of heavy metals in the mycelium of Abortiporus biennis and their effect on oxalate oxidase activity","authors":"Marcin Grąz,&nbsp;Anna Jarosz-Wilkołazka,&nbsp;Jolanta Polak,&nbsp;Bożena Pawlikowska-Pawlęga,&nbsp;Justyna Kapral-Piotrowska,&nbsp;Wioleta Ciempiel,&nbsp;Marta Ruminowicz-Stefaniuk","doi":"10.1007/s10534-025-00675-9","DOIUrl":"10.1007/s10534-025-00675-9","url":null,"abstract":"<div><p><i>Abortiporus biennis</i> belongs to a basidiomycete fungi with the unique ability to degrade oxalate using enzyme oxalate oxidase. Oxalate oxidase (OXO) from <i>Abortiporus biennis</i> is an intracellular oxalic acid-induced enzyme, which catalyses the degradation of oxalic acid to carbon dioxide and hydrogen peroxide. OXO activity was stimulated by all the heavy metals tested (copper, manganese, lead and cadmium) after addition as water-soluble salts to <i>A. biennis</i> fungal cultures. Manganese ions stimulated OXO activity to the greatest extent among the tested metal ions. In the presence of manganese ions, an elevated concentration of oxalate was also detected in the fungal culture after 7 days of cultivation. The manganese, lead, and cadmium ions were accumulated by the <i>A. biennis</i> mycelium. Among them, lead was accumulated to a great extent. It was observed that the accumulation of lead ions occurred in the vicinity of the <i>A.</i> <i>biennis</i> hyphal cell wall.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"38 2","pages":"699 - 710"},"PeriodicalIF":4.1,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143582145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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