Biometals最新文献

{"title":"Berberine-loaded iron oxide nanoparticles alleviate cuprizone-induced astrocytic reactivity in a rat model of multiple sclerosis.","authors":"Ghadha Ibrahim Fouad, Mostafa Mabrouk, Sara A M El-Sayed, Mohamed F Abdelhameed, Maha Z Rizk, Hanan H Beherei","doi":"10.1007/s10534-024-00648-4","DOIUrl":"https://doi.org/10.1007/s10534-024-00648-4","url":null,"abstract":"<p><p>Berberine (BBN) is a naturally occurring alkaloid as a secondary metabolite in many plants and exhibits several benefits including neuroprotective activities. However, data on the neuromodulating potential of nanoformulated BBN are still lacking. In the present study, BBN loaded within iron oxide nanoparticles (BBN-IONP) were prepared and characterized by transmission electron microscopy FTIR, X-ray photoelectron spectroscopy particle-size distribution, zeta potential, and HPLC. The remyelinating neuroprotective potential of BBN-IONP relative to free BBN was evaluated against cuprizone (CPZ)-induced neurotoxicity (rats administered 0.2% CPZ powder (w/w) for five weeks). CPZ rats were treated with either free BBN or IONP-BBN (50 mg/kg/day, orally) for 14 days. Cognitive function was estimated using Y-maze. Biochemically, total antioxidant capacity lipid peroxides and reduced glutathione in the brain tissue, as well as, serum interferon-gamma levels were estimated. Moreover, the genetic expression contents of myelin basic protein Matrix metallopeptidase-9 Tumor necrosis factor-α (TNF-α), and S100β were measured. The histopathological patterns and immunohistochemical assessment of Glial Fibrillary Acidic Protein in both cerebral cortex and hippocampus CA1 regions were investigated. CPZ-rats treated with either free BBN or IONP-BBN demonstrated memory restoring, anti-oxidative, anti-inflammatory, anti-astrocytic, and remyelinating activities. Comparing free BBN with IONP-BBN revealed that the latter altered the neuromodulating activities of BBN, showing superior neuroprotective activities of IONP-BBN relative to BBN. In conclusion, both forms of BBN possess neuroprotective potential. However, the use of IONPs for brain delivery and the safety of these nano-based forms need further investigation.</p>","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of mosses in 'clean and green' phytoremediation technology: a review paper.","authors":"Abiy Gezahegn, Eve Bohnett, Siraj Mammo","doi":"10.1007/s10534-024-00649-3","DOIUrl":"https://doi.org/10.1007/s10534-024-00649-3","url":null,"abstract":"<p><p>Phytoremediation, the practice of removing heavy metals from contaminated sites using plants, has emerged as a cost-effective, environmentally friendly green technology to restore damaged ecosystems. Mosses, in particular, demonstrate high phytoremediation potential due to their ability to accumulate heavy metals such as lead, zinc, copper, chromium, cadmium, and iron from contaminated soil and water. This review systematically examines 37 research articles published from 2000 to 2022, focusing on the on the use of mosses for phytoremediation. Moss species, such as Funaria hygrometrica Hedw, Scopelophila cataractae (Mitten) Brotherus, Dicranum scoparium Hedw, Dicranum polysetum Sw. ex anon, Hypnum cupressiforme Hedw, Physcomitrium cyathicarpum Mitt, Barbula constricta Mitt, and Leptodictyum riparium (Hedw.) Warnst. have been identified as ideal candidates for phytoremediation efforts. Specific species of mosses, such as Dicranum species, are noted for their excellent bioaccumulation capabilities of elements like vanadium, manganese, and rubidium, serving as indicators of air pollution. Additionally, Hypnum cupressiforme has proven to be a reliable indicator of sulfur dioxide in natural and anthropogenic sources. This comprehensive review highlights the significant phytoremediation potential of mosses, emphasizing their role as valuable bioaccumulators and indicators of heavy metals and pollutants. The findings highlight the necessity of further research to enhance the application of mosses in environmental management and remediation strategies, ultimately contributing to the development of sustainable and effective solutions for pollution control.</p>","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Higher cadmium and zinc accumulation in parsley (Petroselinum crispum) roots activates its antioxidants defense system","authors":"Ismat Nawaz,&nbsp;Atifa Mehboob,&nbsp;Aqib Hassan Ali Khan,&nbsp;Tatheer Alam Naqvi,&nbsp;Nazneen Bangash,&nbsp;Sadia Aziz,&nbsp;Wajiha Khan,&nbsp;Irum Shahzadi,&nbsp;Rocío Barros,&nbsp;Kifayat Ullah,&nbsp;Mohammad Maroof Shah","doi":"10.1007/s10534-023-00529-2","DOIUrl":"10.1007/s10534-023-00529-2","url":null,"abstract":"<div><p>Parsley (<i>Petroselinum crispum</i>) is herb with many biological and medicinal benefits for humans. However, growth on zinc (Zn) and cadmium (Cd) contaminated sites might get severely affected due to over accumulation of heavy metals (HM) in different plant tissues. Antioxidants play a crucial role in minimizing the negative effects of HM. The present study investigates the effects of Zn and Cd stress on <i>P. crispum</i> morphological parameters, enzymatic/non-enzymatic antioxidant profiling and metal accumulation in shoot/root. Plants were exposed to different concentrations of Zn (50, 100, 150 and 200 µM) and Cd (10, 20, 40 and 80 µM) along with control (no stress), in soil-less Hoagland's solution. The results showed that Zn and Cd substantially decrease the growth parameters with increased contents of malondialdehyde (MDA), hydrogen peroxide (H₂O₂), and electrolyte leakage (EL). Non-enzymatic antioxidant activities, like total phenolic contents (TPC) and ferric reducing antioxidant power (FRAP), were induced high in leaves only upon Cd stress and contrarily decreased upon Zn stress. Total flavonoid contents (TFC) were decreased under Zn and Cd stress. Enzymatic antioxidant activities like superoxide dismutase (SOD), catalase (CAT) and ascorbate peroxidase (APX) were also strongly induced upon Cd stress. At the same time, SOD and guaiacol peroxidase (GPX) activity was induced significantly upon Zn stress. Cd uptake and accumulation was notably high in roots as compared to shoots, which suggests <i>P. crispum</i> have a reduced ability to translocate Cd towards aboveground parts (leaves). Additionally, strong induction of antioxidants by <i>P. crispum</i> under Cd stress might indicate the capacity to effectively re-modulate its physiological response. However, further investigations regarding other HMs and experiments at the molecular level are still needed.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"37 1","pages":"87 - 100"},"PeriodicalIF":4.1,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10227904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green synthesis of silver nanoparticles from discarded shells of velvet tamarind (Dialium cochinchinense) and their antimicrobial synergistic potentials and biofilm inhibition properties","authors":"Bright Ankudze,&nbsp;David Neglo,&nbsp;Francis Nsiah","doi":"10.1007/s10534-023-00534-5","DOIUrl":"10.1007/s10534-023-00534-5","url":null,"abstract":"<div><p>In the field of nanomedicine, biogenic metal nanoparticles are commonly synthesized using edible plant products as bio-reducing or stabilizing agents. In this study, discarded shell of velvet tamarind fruit is explored as a potent reducing agent for biogenic synthesis of silver nanoparticles (VeV-AgNPs). Silver nanoparticles were formed in minutes under sunlight exposure, which was considerably fast compared to under ambient conditions. The optical, structural and morphological studies revealed that the nanoparticle colloidal solution consisted of particles with quasi-spherical and rodlike morphologies. To investigate antimicrobial properties, eight microorganisms were exposed to the VeV-AgNPs. The results indicated that VeV-AgNPs had enhanced antimicrobial activity, with a recorded minimum inhibitory concentration (MIC) of 3.9 µg/mL against <i>E. coli</i>. Further studies were conducted to examine the biofilm inhibition properties and synergistic effect of the VeV-AgNPs. The findings showed a biofilm inhibition potential of around 98% against <i>E. coli</i>, and the particles were also found to increase the efficacy of standard antimicrobial agents. The combinatory effect with standard antifungal and antibacterial agents ranged from synergistic to antagonistic effects against the tested microorganisms. These results suggest that silver nanoparticles produced from discarded shells of velvet tamarind are potent and could be used as a potential drug candidate to combat antimicrobial resistance.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"37 1","pages":"143 - 156"},"PeriodicalIF":4.1,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10555256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Black phosphorus-incorporated novel Ti-12Mo-10Zr implant for multimodal treatment of osteosarcoma","authors":"Bianyun Cai,&nbsp;Leizhen Huang,&nbsp;Xueke Zhou,&nbsp;Xuan Zhou,&nbsp;Kun Lei,&nbsp;Meng Han,&nbsp;Zilin Zhang,&nbsp;Xiaofang Li,&nbsp;Guangda Li","doi":"10.1007/s10534-023-00533-6","DOIUrl":"10.1007/s10534-023-00533-6","url":null,"abstract":"<div><p>The repair and reconstruction of large bone defects after bone tumor resection is still a great clinical challenge. At present, orthopedic implant reconstruction is the mainstream treatment for repairing bone defects. However, according to clinical feedback, local tumor recurrence and nonunion of bone graft are common reasons leading to the failure of bone defect repair and reconstruction after bone tumor resection, which seriously threaten the physical and mental health of patients. On this basis, here the self-developed low modulus Ti-12Mo-10Zr alloy (TMZ) was chosen as substrate material. To improve its biological activity and osteointegration, calcium, oxygen, and phosphorus co-doped microporous coating was prepared on TMZ alloy by microarc oxidation (MAO). Then, black phosphorus (BP) nanosheets were incorporated onto MAO treated TMZ alloy to obtain multifunctional composites. The obtained BP-MAO-TMZ implant exhibited excellent photothermal effects and effective ablation of osteosarcoma cancer cells under the irradiation of 808 nm near infrared laser, while no photothermal or therapeutic effects were observed for TMZ alloy. Meanwhile, the structure/component bionic coating obtained after MAO treatment as well as the P-driven in situ biomineralization performance after incorporation of BP nanosheets endowed BP-MAO-TMZ implant with synergistic promoting effect on MC3T3-E1 osteoblasts’ activity, proliferation and differentiation ability. This study is expected to provide effective clinical solutions for problems of difficult bone regeneration and tumor recurrence after tumor resection in patients with bone tumors and to solve a series of medical problems such as poor prognosis and poor postoperative quality of patients life with malignant bone tumors.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"37 1","pages":"131 - 142"},"PeriodicalIF":4.1,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10186183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibacterial and antioxidant activity of gold and silver nanoparticles in dextran–polyacrylamide copolymers","authors":"Anton Tkachenko,&nbsp;Sadin Özdemir,&nbsp;Gülşah Tollu,&nbsp;Nadir Dizge,&nbsp;Kasim Ocakoglu,&nbsp;Volodymyr Prokopiuk,&nbsp;Anatolii Onishchenko,&nbsp;Vasyl Сhumachenko,&nbsp;Pavlo Virych,&nbsp;Vadym Pavlenko,&nbsp;Nataliya Kutsevol","doi":"10.1007/s10534-023-00532-7","DOIUrl":"10.1007/s10534-023-00532-7","url":null,"abstract":"<div><p>Search for new antimicrobial agents is of great significance due to the issue of antimicrobial resistance, which nowadays has become more important than many diseases. The aim of this study was to evaluate the toxicity and biological effects of a dextran-graft-polyacrylamide (D-PAA) polymer-nanocarrier with/without silver or gold nanoparticles (AgNPs/D-PAA and AuNPs/D-PAA, respectively) to analyze their potential to replace or supplement conventional antibiotic therapy. The toxicity of nanocomplexes against eukaryotic cells was assessed on primary dermal fibroblasts using scratch, micronucleus and proliferation assays. DPPH (2,2-diphenyl-1-picrylhydrazylradical) assay was used to evaluate the antioxidant capacity of D-PAA, AgNPs/D-PAA and AuNPs/D-PAA. DNA cleavage, antimicrobial and biofilm inhibition effects of nanocomplexes were investigated. Nanocomplexes were found to be of moderate toxicity against fibroblasts with no genotoxicity observed. AgNPs/D-PAA reduced motility and proliferation at lower concentrations compared with the other studied nanomaterials. AgNPs/D-PAA and AuNPs/D-PAA showed radical scavenging capacities in a dose-dependent manner. The antimicrobial activity of AgNPs/D-PAA against various bacteria was found to be much higher compared to D-PAA and AuNPs/D-PAA, especially against <i>E. hirae, E. faecalis</i> and <i>S. aureus</i>, respectively. D-PAA, AgNPs/D-PAA and AuNPs/D-PAA showed DNA-cleaving and biofilm inhibitory activity, while AgNPs/D-PAA displayed the highest anti-biofilm activity. AgNPs/D-PAA and AuNPs/D-PAA were characterized by good antimicrobial activity. According to the findings of the study, AgNPs/D-PAA and AuNPs/D-PAA can be evaluated as alternatives for the preparation of new antimicrobial agents, the fight against biofilms, sterilization and disinfection processes. Our findings confirm the versatility of nanosystems based on dextran–polyacrylamide polymers and indicate that AgNPs/D-PAA and AuNPs/D-PAA can be evaluated as alternatives for the preparation of novel antimicrobial agents.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"37 1","pages":"115 - 130"},"PeriodicalIF":4.1,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10119862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro cadmium exposure induces structural damage and endothelial dysfunction in female rat aorta","authors":"Lorraine Christiny Costa Sepulchro Mulher,&nbsp;Rakel Passos Simões,&nbsp;Karoline Alves Rossi,&nbsp;Ingridy Reinholz Grafites Schereider,&nbsp;Camilla Lóren da Silva Nascimento,&nbsp;Renata Andrade Ávila,&nbsp;Alessandra Simão Padilha","doi":"10.1007/s10534-023-00526-5","DOIUrl":"10.1007/s10534-023-00526-5","url":null,"abstract":"<div><p>Cadmium is a heavy metal that is widespread in the environment and has been described as a metalloestrogen and a cardiovascular risk factor. Experimental studies conducted in male animals have shown that cadmium exposure induces vascular dysfunction, which could lead to vasculopathies caused by this metal. However, it is necessary to investigate the vascular effects of cadmium in female rats to understand its potential sex-dependent impact on the cardiovascular system. While its effects on male rats have been studied, cadmium may act differently in females due to its potential as a metalloestrogen. In vitro studies conducted in a controlled environment allow for a direct assessment of cadmium's impact on vascular function, and the use of female rats ensures that sex-dependent effects are evaluated. Therefore, the aim of this study was to investigate the in vitro effects of Cadmium Chloride (CdCl₂, 5 µM) exposure on vascular reactivity in the isolated aorta of female Wistar rats. Exposure to CdCl₂ damaged the architecture of the vascular endothelium. CdCl₂ incubation increased the production and release of O₂^•−, reduced the participation of potassium (K⁺) channels, and increased the participation of the angiotensin II pathway in response to phenylephrine. Moreover, estrogen receptors alpha (Erα) modulated vascular reactivity to phenylephrine in the presence of cadmium, supporting the hypothesis that cadmium could act as a metalloestrogen. Our results demonstrated that in vitro cadmium exposure induces damage to endothelial architecture and an increase in oxidative stress in the isolated aorta of female rats, which could precipitate vasculopathies.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div><div><p>Graphical Abstract. Own source from Canva and Servier Medical Art servers</p></div></div></figure></div></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"36 6","pages":"1405 - 1420"},"PeriodicalIF":3.5,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10495704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous binding characterization of different chromium speciation to serum albumin","authors":"Ye Li,&nbsp;Yanxuan Ma,&nbsp;Chunyu Mu,&nbsp;Jiali Gu,&nbsp;Zimu Li","doi":"10.1007/s10534-023-00531-8","DOIUrl":"10.1007/s10534-023-00531-8","url":null,"abstract":"<div><p>The binding process between three species of chromium and serum albumin (SA) was investigated, as well as the interaction between K₂Cr₂O₇ and bovine serum albumin (BSA) under coexistence of different chromium forms. CrCl₃, K₂Cr₂O₇ and Crpic bound to SA spontaneously through Van der Waals force, and their binding constants were 10³–10⁴ M⁻¹ at 298 K, respectively. K₂Cr₂O₇ and Crpic both had strong binding affinity for BSA, and significantly affected the secondary structure of BSA and the microenvironment surrounding amino acid residues. Chromium exhibited a greater fluorescence quenching constant towards HSA than toward BSA, and K₂Cr₂O₇ induced greater conformational changes in human serum albumin (HSA) than in BSA. A weak binding of CrCl₃ to BSA had no significant effect on the binding affinity of K₂Cr₂O₇ to BSA. K₂Cr₂O₇ and BSA have a greater binding affinity when coexisting with Crpic, and K₂Cr₂O₇ induces a greater conformational change in BSA.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"37 1","pages":"101 - 113"},"PeriodicalIF":4.1,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10043009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are high copper levels related to Alzheimer’s and Parkinson’s diseases? A systematic review and meta-analysis of articles published between 2011 and 2022","authors":"Fabielly Scolari Grotto,&nbsp;Viviane Glaser","doi":"10.1007/s10534-023-00530-9","DOIUrl":"10.1007/s10534-023-00530-9","url":null,"abstract":"<div><p>Copper performs an important role in the brain, but in high levels it can be neurotoxic. Further, some authors have described that copper dyshomeostasis could be related with neurodegenerative diseases. Thus, this review was performed to observe whether high copper levels are related to Alzheimer’s and Parkinson’s diseases (AD and PD), using the literature published recently. Articles that measured copper levels in AD or PD patients was included, as well as they that measured copper levels in models used to mimic these diseases. Also, results about high copper levels effects and its relationship with AD and PD observed in laboratory animals are considered. In summary, 38 and 24 articles with AD and PD patients were included, respectively. Despite of the heterogeneity between the studies in humans, meta-analysis has demonstrated that there is an increase in free and total copper levels in the blood of AD patients compared to controls, and a decrease in copper levels in PD patients. A decrease in the metal content in <i>postmortem</i> brain tissue was observed in AD and PD. In manuscripts using animal models that mimic AD and PD, it was included seven and three articles, respectively. Two of them have reported an increase in copper concentrations in AD model, and one in PD model. Finally, studies with laboratory animals have concluded that high copper levels are related to oxidative stress, neuroinflammation, mitochondrial dysfunction, changes in neurotransmitter levels, cell death, and reduced both cognitive and locomotor activity, which are also described in AD or PD.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"37 1","pages":"3 - 22"},"PeriodicalIF":4.1,"publicationDate":"2023-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10012735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioaccumulation of Titanium in diatom Cyclotella atomus Hust","authors":"Elumalai Sanniyasi,&nbsp;Rajesh Kanna Gopal,&nbsp;Rajesh Damodharan,&nbsp;Tarani Thirumurugan,&nbsp;Vishali Mahendran","doi":"10.1007/s10534-023-00528-3","DOIUrl":"10.1007/s10534-023-00528-3","url":null,"abstract":"<div><p>Diatomaceous earth or diatomite is a fossil rock deposit of diatoms made up of silica and other minerals. A distinguishing feature of diatoms that placed them in the single class of microalgae Bacillariophyceae, is the frustule, a transparent, hard-shelled cell wall. It's interesting to note that the diatom has specific proteins and enzymes for heavy metal detoxification and can intake and store more heavy metals in its frustule. Consequently, an attempt has been made in this study to determine the bioaccumulation of metals in the frustules of the diatom. Hence, a centric diatom was isolated from the freshwater sample collected from the Adyar River, Chennai, Tamil Nadu. The diameter of the cell was 5–7.5 µm and 20–23 striations with radial arrangement. A single, dark off-center fultoportula and marginal fultoportula on the striae are found in the diatom. Additionally, one rimoportula between two marginal fultoportula distributed on the striae between the costa was also seen. As a result, the isolated diatom was morphologically identified as <i>Cyclotella atomus</i> Hust. Simultaneously, the bioaccumulation study reveals that the Titanium (Ti) was found accumulated in the frustules of the diatom incubated in the Ti-supplemented culture medium based on the scanning electron microscope-energy-dispersive X-ray analysis (SEM-EDAX). Therefore, the biogenic accumulation and fabrication of Titanium frustules in diatom have advantages in enhancing the efficiency of solar cells.</p></div>","PeriodicalId":491,"journal":{"name":"Biometals","volume":"37 1","pages":"71 - 86"},"PeriodicalIF":4.1,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10328039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}