Biometals最新文献_第2页

Efficient removal of Cr(VI) ions by Staphylococcus aureus CC1956: biosorption isotherm and kinetic modeling. 金黄色葡萄球菌CC1956对Cr（VI）离子的高效去除：生物吸附等温线和动力学模型。

IF 3.6 3区生物学

Biometals Pub Date : 2025-08-06 DOI: 10.1007/s10534-025-00734-1

Kaoutar Harboul, Halima Amakdouf, Khalil Hammani, Abdenbi El-Karkouri

{"title":"Efficient removal of Cr(VI) ions by Staphylococcus aureus CC1956: biosorption isotherm and kinetic modeling.","authors":"Kaoutar Harboul, Halima Amakdouf, Khalil Hammani, Abdenbi El-Karkouri","doi":"10.1007/s10534-025-00734-1","DOIUrl":"https://doi.org/10.1007/s10534-025-00734-1","url":null,"abstract":"Chromium in its hexavalent form (Cr(VI)) is a highly toxic environmental pollutant that poses severe risks to human health and ecosystems. Staphylococcus aureus can play a role in the removal of Cr(VI) from aqueous solutions, primarily through a process of reduction and subsequent biosorption. While it's not as widely studied for this purpose as some other bacterial species, it has been shown to reduce and bind Cr(VI), potentially offering a way to remediate contaminated environments. This study assessed the biosorption potential of the bacterial strain Staphylococcus aureus CC1956, which tolerates Cr(VI) levels up to 700 mg/L. The strain demonstrated significant Cr(VI) removal across various conditions, including pH values from 5.0 to 9.0, temperatures ranging from 25 to 45 °C, and initial Cr(VI) concentrations between 50 and 300 mg/L. Competing anions exerted minimal influence on biosorption efficiency, whereas adding glucose significantly enhanced Cr(VI) removal. The adsorption data were best described by the Langmuir isotherm model, indicating a monolayer binding of Cr(VI) onto the bacterial surface. The main functional groups involved in the biosorption process revealed by FTIR analysis are hydroxyl, phosphoryl, carboxyl, and amine groups in the binding of Cr(VI). SEM-EDX analysis also confirmed the association of chromium with the cell surface. These findings highlight the potential of S. aureus CC1956 as an effective biosorbent for Cr(VI) and its promising application in the bioremediation of contaminated wastewater.","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144788013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Selenium-biofortified Gboma (Solanum macrocarpon L.) vegetable-supplemented diets increased circulating selenium levels and potentiated endogenous anti-inflammatory, antioxidant and immunomodulatory properties in Wistar rats. 添加硒生物强化茄（Solanum macrocarpon L.）蔬菜的饲粮可提高Wistar大鼠循环硒水平，增强内源性抗炎、抗氧化和免疫调节特性。

IF 3.6 3区生物学

Biometals Pub Date : 2025-08-05 DOI: 10.1007/s10534-025-00733-2

Inioluwa Ayooluwa Odeyemi, Jesutomi Aduragbemi Oyediran, Adedayo Oluwaseun Ademiluyi, Ganiyu Oboh, Opeyemi Babatunde Ogunsuyi

{"title":"Selenium-biofortified Gboma (Solanum macrocarpon L.) vegetable-supplemented diets increased circulating selenium levels and potentiated endogenous anti-inflammatory, antioxidant and immunomodulatory properties in Wistar rats.","authors":"Inioluwa Ayooluwa Odeyemi, Jesutomi Aduragbemi Oyediran, Adedayo Oluwaseun Ademiluyi, Ganiyu Oboh, Opeyemi Babatunde Ogunsuyi","doi":"10.1007/s10534-025-00733-2","DOIUrl":"https://doi.org/10.1007/s10534-025-00733-2","url":null,"abstract":"Selenium biofortification of staple foods is a strategy for ameliorating Selenium deficiency among populations. The aim of this study is to investigate the effect of Selenium biofortification on some phytochemicals present in Gboma (Solanum macrocarpon L.) leaves and to assess the effect of its dietary inclusions on some antioxidant molecules, immunoglobulins and inflammatory cytokines in the serum of Wistar rats. Gboma, also called African Eggplant was cultivated on soil enriched with Selenium biofortified fertilizer and harvested at maturity. The phytochemicals present were assessed via HPLC. The samples were also included into the diet of Wistar rats (4% and 8% inclusions) for fourteen days. The serum was then collected and assayed for glutathione peroxidase (GPx), glutathione-S-transferase (GST) and catalase activities. Imuunoglobulins M, G, A and E as well as the inflammatory makers-tumor necrosis factor-α and interleukin-10 were also assayed for. The results showed that Selenium bioaccumulation increased the concentration of some phytochemicals such as chlorogenic acid, 4- hydroxybenzoic acid and delphinidin. An increase in the activity of the antioxidant enzymes was also observed in rats fed with Selenium biofortified Gboma leaves (4% and 8%), compared to control and rats fed diets supplemented with Gboma leaves without Selenium biofortification. In addition, IgG, IgM and IgA levels increased in the serum of treated rats, coupled with an increase in IL-10 levels. This study therefore, shows that Selenium biofortification enhanced the antioxidant and immunomodulatory properties of Gboma leaves.","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144783076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prenatal iron overload induces hepatic oxidative stress and ferroptosis in offspring mice. 产前铁超载诱导后代小鼠肝脏氧化应激和铁下垂。

IF 3.6 3区生物学

Biometals Pub Date : 2025-08-05 DOI: 10.1007/s10534-025-00732-3

Yi Yan, Qing Yang, Yanqiu Zhu, Hongrui Guo

{"title":"Prenatal iron overload induces hepatic oxidative stress and ferroptosis in offspring mice.","authors":"Yi Yan, Qing Yang, Yanqiu Zhu, Hongrui Guo","doi":"10.1007/s10534-025-00732-3","DOIUrl":"https://doi.org/10.1007/s10534-025-00732-3","url":null,"abstract":"Iron is an essential micronutrient required for normal growth and development. However, excessive iron intake can exert toxic effects, particularly during sensitive developmental windows such as pregnancy. In this study, pregnant female mice were supplemented with varying concentrations of iron until day 21 post-delivery. On postnatal days 0 and 21, we assessed the body weight, liver index, hepatic iron content, antioxidant capacity, and expression of ferroptosis-related proteins in the offspring. Excessive maternal iron supplementation significantly decreased both body and liver weights of offspring and induced histopathological abnormalities in hepatic tissue. Liver iron levels were markedly elevated, accompanied by significant reductions in the activities of antioxidant enzymes including T-AOC, CAT, GSH-Px, and SOD, as well as decreased hepatic GSH content. Moreover, iron overload increased the protein expression levels of p-AMPKα/AMPKα, p-ULK1/ULK1, Beclin1, FTH1, and COX2, while decreasing the levels of SLC7A11, GPX4, and NCOA4. Collectively, these findings suggest that excessive iron supplementation during pregnancy leads to hepatic iron accumulation, oxidative stress, and ferroptosis in offspring mice.","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144783075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ferrous sulfate and lipopolysaccharide co-exposure induce neuroinflammation, neurobehavioral motor deficits, neurodegenerative and histopathological biomarkers relevant to Parkinson's disease-like symptoms in Wistar rats. 硫酸亚铁和脂多糖共暴露诱导Wistar大鼠神经炎症、神经行为运动缺陷、神经退行性和与帕金森病样症状相关的组织病理学生物标志物。

IF 3.6 3区生物学

Biometals Pub Date : 2025-08-01 Epub Date: 2025-05-16 DOI: 10.1007/s10534-025-00693-7

Shivam Kumar Pandey, Anjuman Nanda, Avtar Singh Gautam, Apurva Chittoda, Aman Tiwari, Rakesh Kumar Singh

{"title":"Ferrous sulfate and lipopolysaccharide co-exposure induce neuroinflammation, neurobehavioral motor deficits, neurodegenerative and histopathological biomarkers relevant to Parkinson's disease-like symptoms in Wistar rats.","authors":"Shivam Kumar Pandey, Anjuman Nanda, Avtar Singh Gautam, Apurva Chittoda, Aman Tiwari, Rakesh Kumar Singh","doi":"10.1007/s10534-025-00693-7","DOIUrl":"10.1007/s10534-025-00693-7","url":null,"abstract":"Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra region of the brain. Although iron is one of the essential micronutrients in the brain, its excess exposure and accumulation in the brain substantia nigra and striatum regions may induce critical pathological changes relevant to PD. This study has evaluated neurobehavioral, biochemical, and structural alterations resembling PD-like symptoms induced through a 4-week co-exposure of ferrous sulfate (FeSO4) with lipopolysaccharide (LPS) in Wistar rats. Our results revealed motor deficits, oxidative stress, neuroinflammation, iron dysregulation, protein aggregation, ferroptosis, and apoptotic cell death. Notably, we observed decreased tyrosine hydroxylase levels and increased α-synuclein accumulation, consistent with PD pathology. The immunohistopathological assessments showed astrocyte activation and iron deposition, supporting their roles in neuroinflammation and oxidative stress. Furthermore, we identified alterations in apoptosis and ferroptosis markers, suggesting dose-related involvement of FeSO4 in neuronal death in the rat brain. These findings have highlighted the multifaceted mechanisms during the co-exposure of FeSO4 and LPS-induced neurodegeneration and neuroinflammation relevant to PD. This study emphasizes that therapeutic targeting of these pathological mechanisms may offer a promising therapeutic intervention in PD.","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":"1083-1107"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, characterization and biological potential of nitroso-R salt with transition metal complexes. 含过渡金属配合物的亚硝基r盐的合成、表征及生物潜力。

IF 3.6 3区生物学

Biometals Pub Date : 2025-08-01 Epub Date: 2025-05-29 DOI: 10.1007/s10534-025-00698-2

Saddam Hussain, Mehreen Zafar, Nauman Ali, Takashiro Akitsu, Waseem Hassan

{"title":"Synthesis, characterization and biological potential of nitroso-R salt with transition metal complexes.","authors":"Saddam Hussain, Mehreen Zafar, Nauman Ali, Takashiro Akitsu, Waseem Hassan","doi":"10.1007/s10534-025-00698-2","DOIUrl":"10.1007/s10534-025-00698-2","url":null,"abstract":"Coordination complexes exhibited interesting potentials in different fields such as medical, industrial, pharmaceutical, and analytical. They possess versatile biological applications in drugs synthesis, extraction of noble metals like silver and gold from their ores and in metals purification. In current project we aim to synthesized and characterized transition metal complexes like Mn, Fe, Co, Ni, Cu and Zn using Nitroso-R Salt as a ligand. This study presents a novel approach to develop stable metal complexes using Nitroso R Salt, a ligand comprising nitrosyl, hydroxyl, and sulfonate groups. This study offers a combined analysis of both chemical and functional properties, which was not commonly investigated with NRS, by combining biological screening with thorough structural characterizations (FTIR, CHN, XRD and UV). The complexes were then subjected to various tests to explore their deoxyribose degradation inhibition potential, antioxidant and antimicrobial potential. Copper and Zinc Complexes showed good potential 173 and 182% against iron at 100 mM. The highest potential was recorded for Nickel complex potential 2, 7 and 14% against H2O2, Fe (II) and in combine form. It was further confirmed respectively by antioxidant DPPH assay. Ligand and complexes showed good inhibitory potential by showing 18.66, 39.32, 38.22, 28.89, 20.71, 19.14 and 28.89% for NRS, Iron, Cobalt, Nickel, Zinc, Copper and Manganese complexes at high concentration of 200uM, respectively. The complexes showed promising antibacterial and antioxidant properties. Nickel complexes demonstrated a strong inhibition against reactive species, but copper and zinc complexes showed a notably high antioxidant capacity. Effective inhibitory zones were found in antimicrobial testing, especially for Fe, Mn, Co, and Cu complexes against Klebsiella pneumoniae and Bacillus subtilis. However, further studies are needed to examine the exact mechanisms of action of these discoveries, which point to possible biomedical uses.","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":"1165-1177"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanism for the decrease of Cd uptake and transport within wheat plants in the presence of dissolved Fe(II). 溶解铁（II）存在下小麦植株Cd吸收和转运减少的机制

IF 3.6 3区生物学

Biometals Pub Date : 2025-08-01 Epub Date: 2025-06-12 DOI: 10.1007/s10534-025-00697-3

Xianjie Duan, Ling Liu, Tao Lu, Ziwei Wang, Sheliang Wang, Chengshuai Liu, Guohong Qiu

{"title":"Mechanism for the decrease of Cd uptake and transport within wheat plants in the presence of dissolved Fe(II).","authors":"Xianjie Duan, Ling Liu, Tao Lu, Ziwei Wang, Sheliang Wang, Chengshuai Liu, Guohong Qiu","doi":"10.1007/s10534-025-00697-3","DOIUrl":"10.1007/s10534-025-00697-3","url":null,"abstract":"Dissolved Fe(II) influences Cd uptake and transport within wheat plants, but the specific interaction process remains elusive. This study used synchrotron radiation technology, Fourier transform infrared spectroscopy, high-performance liquid chromatography, ion chromatography, and RT-PCR to analyze the interaction processes of Fe(II) and Cd(II) ions in the roots of wheat grown in hydroponic systems containing Cd(II). The results indicated that dissolved Fe(II) decreases Cd uptake due to rhizosphere passivation, cell wall binding or blocking, and competitive absorption and regulation. Poorly crystalline Fe(III) oxides were newly formed, which facilitated the immobilization of Cd(II) on the rhizoplane (over 78%) in a hydroponic system with 5 μmol L-1 Cd(II). Binding of Cd(II) by cell wall depended on pectin and phosphate contents in the presence of Fe(II). Higher accumulation of lignin in the root endodermis blocked Cd(II) transport at 1000 μmol L-1 Fe(II). The Fe(II) level influenced Cd uptake by regulating the content of rhizosphere Cd(II) ions and the expression of Cd(II) uptake genes in a hydroponic system with 5 μmol L-1 Cd(II). The content of CaCl2-extractable Cd(II) was decreased by 45.4% and the expression of Cd(II) uptake genes was significantly down-regulated with Fe(II) concentration increasing from 15 to 1000 μmol L-1. In the high-concentration Cd(II) (15 μmol L-1) system, the inhibitory effect of dissolved Fe(II) on Cd uptake decreased due to increases in rhizosphere Cd content and expression of Cd(II) uptake genes. This work suggests that dissolved Fe(II) can reduce Cd uptake of wheat plants and provides fundamental data for food security.","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":"1145-1164"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144281934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of combined exposure to multiple metals with comorbid obesity and myopia in the U.S. population. 美国人群多重金属暴露与合并症肥胖和近视的关系

IF 3.6 3区生物学

Biometals Pub Date : 2025-08-01 Epub Date: 2025-06-11 DOI: 10.1007/s10534-025-00701-w

Li He, Yalan Liu, Li Zhang, Ying Luo, Zhaofeng Jin

{"title":"Association of combined exposure to multiple metals with comorbid obesity and myopia in the U.S. population.","authors":"Li He, Yalan Liu, Li Zhang, Ying Luo, Zhaofeng Jin","doi":"10.1007/s10534-025-00701-w","DOIUrl":"10.1007/s10534-025-00701-w","url":null,"abstract":"The objective of this study was to examine the relationships between combined metal exposure and the comorbidities of overweight/obesity (OWOB) and myopia. Data from the National Health and Nutrition Examination Survey (2001-2006) were analyzed. The sample comprised 5927 participants aged 12 years and older, with urine measurements of 11 metals obtained through inductively coupled plasma-mass spectrometry. Least absolute shrinkage and selection operator regression models were employed to evaluate the combined effects of the metals. Multivariate logistic regression models and restricted cubic spline functions assessed the connections between metal exposure and comorbidities. The findings indicated that 1290 (21.76%) of the 5927 participants exhibited both OWOB and myopia. High levels of lead (OR = 0.76, 95% CI: 0.62-0.93), platinum (OR = 0.81, 95% CI: 0.68-0.97), and uranium (OR = 0.72, 95% CI: 0.59-0.86) were associated with a reduced risk of these comorbidities (P trend < 0.05). Conversely, elevated exposure to mixed metals was linked to an increased risk of comorbidities (OR = 1.48, 95% CI: 1.23-1.77, P trend < 0.0001). Females had a higher risk of exposure to mixed metals (OR = 4.63, 95% CI: 2.63-8.16) compared to males (OR = 1.45, 95% CI: 0.74-2.82). This study offers preliminary evidence of an association between metal exposure and the comorbidity of OWOB and myopia. Although causality cannot be inferred due to the cross-sectional nature of the study, these results support further longitudinal research.","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":"1223-1233"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spatial heterogeneity in copper distribution changed antioxidant capacity of container-grown Camphora officinarum roots under excessive copper stress. 铜分布的空间异质性改变了容器樟树根在过量铜胁迫下的抗氧化能力。

IF 3.6 3区生物学

Biometals Pub Date : 2025-08-01 Epub Date: 2025-06-16 DOI: 10.1007/s10534-025-00707-4

Boya Chen, Shiyun Wu, Ying Zhang, Ming Yang, Chunliang Zhou, Yumei Zhou

{"title":"Spatial heterogeneity in copper distribution changed antioxidant capacity of container-grown Camphora officinarum roots under excessive copper stress.","authors":"Boya Chen, Shiyun Wu, Ying Zhang, Ming Yang, Chunliang Zhou, Yumei Zhou","doi":"10.1007/s10534-025-00707-4","DOIUrl":"10.1007/s10534-025-00707-4","url":null,"abstract":"Coating high concentrations of copper (Cu) on the inner wall of containers prevents root entanglement by inhibiting root tip elongation. However, it remains uncertain whether roots near and far from the container wall differentially absorb Cu, thereby triggering varied defense responses. Two-year-old Camphora officinarum were planted in containers coated with 120 (T1) and 200 (T2) g L-1 Cu(OH)2 with latex as the carrier. After six months of treatment, obvious root entanglement in containers only coated with latex (T0) and control containers was observed, while no entanglement in T1 and T2. Cu(OH)2 treatment increased soil and root Cu concentration, which exhibited significant position differences (near-wall vs. far-wall) in T1 and T2. Root Cu concentration near the container wall in T1 and T2 was 3.5 and 3.0 times higher than that far from the container wall, and 19.3 and 32.1 times higher than that in the control. Oxidative stress biomarkers increased with increasing root Cu concentration with the highest levels near the container wall in T2. Excessive Cu increased antioxidant enzyme activities and non-enzymatic antioxidant contents with higher superoxide dismutase, glutathione reductase, glutathione peroxidase, ascorbate peroxidase, ascorbate acid, and reduced glutathione in T1 and higher dehydroascorbate reductase and monodehydroascorbate in T2. Overall, antioxidant enzyme activity in roots was higher near the container wall in T1 while far from the container wall in T2. Excessive and uneven Cu distribution and oxidative stress biomarkers effectively inhibited peripheral root elongation and entanglement. During this process, although antioxidant defense responses were induced, defense capacity was impaired by supra-optimal Cu.","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":"1299-1314"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thermophiles in nanosized biocalcification: a novel approach for heavy metal remediation. 纳米级生物钙化中的嗜热菌：重金属修复的新方法。

IF 3.6 3区生物学

Biometals Pub Date : 2025-08-01 Epub Date: 2025-05-24 DOI: 10.1007/s10534-025-00700-x

Sujata Negi, Shagun Sharma, Deepak Pant, Sonali Sharma, Kalpana Chauhan, Anand Giri, Manoj Kumar, Kulamani Parida

{"title":"Thermophiles in nanosized biocalcification: a novel approach for heavy metal remediation.","authors":"Sujata Negi, Shagun Sharma, Deepak Pant, Sonali Sharma, Kalpana Chauhan, Anand Giri, Manoj Kumar, Kulamani Parida","doi":"10.1007/s10534-025-00700-x","DOIUrl":"10.1007/s10534-025-00700-x","url":null,"abstract":"Bio deposition of minerals is a prevalent occurrence in the biological realm, facilitated by various organisms such as bacteria, fungi, protists, and plants. Calcium carbonate is one such mineral that precipitates naturally as a consequence of microbial metabolic processes. This study investigates an innovative approach for MICP- mediated heavy metal remediation, carbon dioxide (CO2) sequestration by utilizing thermophilic microorganisms isolated from such geographical area which is not yet been subjected to any systematic scientific study. Beyond the well-established urea hydrolysis pathway, this research highlights the contribution of non-ureolytic MICP mechanisms driven by the oxidation of organic compounds within the bacterial extracellular polymeric substances and cell wall components of Bacillus licheniformis. Notably, both strains of Bacillus licheniformis redirect its great potential towards biocalcification yielding 89.36 ± 1.8, 88.21 ± 1.5 mg CaCO3 cells/ml and 90% efficiency for heavy metal remediation with the formation of nanosized (35.85 nm, 38.58 nm) biominerals. The influence of various parameters, such as temperature, pH, incubation time, CO2 concentration, and calcium concentration on maximum CaCO3 biosynthesis was evaluated. FTIR, XRD, and SEM-EDX analyses confirmed characteristic peaks for both calcite and vaterite polymorphs, consistent with these Pb incorporation into the mineral structure, rather than surface adsorption is observed. These comparative findings provide valuable insights for promising bioremediation approach for the sustainable, eco-friendly, energy-efficient immobilization of metal contaminants and bio-based carbonate production for efficient CO2 sequestration.","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":"1203-1221"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hexavalent chromium induced bioaccumulation, oxidative responses and histological anomalies in freshwater carp Labeo rohita (Hamilton, 1822). 六价铬诱导淡水鲤鱼Labeo rohita的生物蓄积、氧化反应和组织学异常（Hamilton, 1822）。

IF 3.6 3区生物学

Biometals Pub Date : 2025-08-01 Epub Date: 2025-06-24 DOI: 10.1007/s10534-025-00708-3

Archisman Ray, Debashri Mondal, Debapriyo Mukherjee, Nabanita Chakraborty

{"title":"Hexavalent chromium induced bioaccumulation, oxidative responses and histological anomalies in freshwater carp Labeo rohita (Hamilton, 1822).","authors":"Archisman Ray, Debashri Mondal, Debapriyo Mukherjee, Nabanita Chakraborty","doi":"10.1007/s10534-025-00708-3","DOIUrl":"10.1007/s10534-025-00708-3","url":null,"abstract":"The toxicity of chromium, in its hexavalent form (Cr(VI)), is extremely harmful to living organisms owing to its potent oxidizing properties. The present research focused in exploring the hexavalent chromium induced bioaccumulation, oxidative responses and histological anomalies in widely cultured freshwater carp Labeo rohita. Fingerlings of L. rohita were exposed to four sub-lethal waterborne concentrations of 96 h LC50 (1/40th, 1/20th, 1/10th and 1/5th) of the Cr(VI). The impact of chromium was assessed in 5, 15 and 30 days exhibiting significant accumulation (P < 0.05) in the fish tissues (gill > kidney > liver > muscles) with increasing concentration. The bioaccumulation factor (BAF) also exhibited the highest in the liver tissue and least in muscle. Antioxidant enzymes like superoxidase dismutase (SOD) in the gill, liver and kidney increased significantly with the concentrations, while catalase (CAT) activity was found to fluctuate along different concentrations. Significant reduction in growth performance i.e. SGR and reduced feeding intensity was also observed after 30th day. The histopathological examination revealed epithelial hyperplasia in the gill tissues and vacuolization and shrinkage of hepatocytes in the liver tissues. Chromium toxicity-induced alterations in kidney tissues were also characterized by glomerular shrinkage and an increase in Bowman's space. Overall, the study demonstrated that hexavalent chromium exerts significant impact on accumulation, oxidative stress, and histological anomalies, particularly at higher concentrations, in the fingerlings of L. rohita. Therefore, effective treatment of wastewater below the studied concentrations from anthropogenic sources prior to its release into aquatic environments is vital to avert pollution and safeguard the sustainability of aquatic life.","PeriodicalId":491,"journal":{"name":"Biometals","volume":" ","pages":"1315-1335"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0