Medicina Oral Patologia Oral Y Cirugia Bucal最新文献

{"title":"Oral Medicine in Latin America and the Caribbean: A comprehensive survey of recognition, training, and practice.","authors":"C Saldivia-Siracusa, L-V González-Pérez, C Rivera, D-P Guevara, D Aviles, E-D Piemonte, E-C Garcia, E Contreras-Vidaurre, G Anaya-Saavedra, G-G Pérez, G-J Gómez, I Rios, L-P Espinal, N-A Londoño, R-A Rejas, R Epifanio, S-C Mora, S-V Celhay, M-A Lopes, A-R Santos-Silva","doi":"10.4317/medoral.26944","DOIUrl":"10.4317/medoral.26944","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the scope of training and practice in Oral Medicine in Latin American and Caribbean countries. It explored legal, professional, and academic scope of regional OM practice, as well as current challenges perceived by experts in the field.</p><p><strong>Material and methods: </strong>We employed an observational, cross-sectional approach, utilizing a self-administered questionnaire delivered through the REDCap web platform.</p><p><strong>Results: </strong>Oral Medicine is officially recognized as a dental specialty in 66.7% of Latin American and Caribbean countries, and 66.7% countries recognize it as a standalone field, separate from Oral Pathology. Additionally, 23.8% of the surveyed countries have national postgraduate Oral Medicine programs. Nearly half (47.6%) of the countries lack specific regulations, and there is significant variation in understanding clinical competencies. Private practice emerged as the dominant field of work for Oral Medicine practitioners. Notably, 90.5% of respondents identified the lack of recognition by multidisciplinary teams as a significant barrier to the practice.</p><p><strong>Conclusions: </strong>This study provides information on the current landscape of Oral Medicine practice in Latin American and Caribbean countries. It highlights disparities in recognition, regulation, and performance of the specialty. These findings call for international initiatives aimed at enhancing training pathways, scope of practice and the impact of Oral Medicine in the region.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e363-e372"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019656/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between prediabetes and periodontitis: a meta-analysis of observational studies with multivariate analysis.","authors":"Y Zhou, F Sun, Q Zhu","doi":"10.4317/medoral.26961","DOIUrl":"10.4317/medoral.26961","url":null,"abstract":"<p><strong>Background: </strong>Growing evidence suggests that prediabetes may increase the risk of periodontitis, though the extent of this association remains unclear. To provide a clearer understanding, this meta-analysis focused on observational studies that utilized multivariate analyses to adjust for key confounding factors.</p><p><strong>Material and methods: </strong>A comprehensive search of PubMed, Embase, and Web of Science was conducted to identify observational studies assessing the relationship between prediabetes and periodontitis. Only studies that utilized multivariate analyses were included to minimize confounding bias. The quality of the studies was evaluated with the Newcastle-Ottawa Scale (NOS). Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using a random-effects model, with heterogeneity assessed by the I² statistic.</p><p><strong>Results: </strong>Ten observational studies with 38,727 participants were included. Overall, individuals with prediabetes had a significantly higher risk of periodontitis compared to normoglycemic individuals (OR: 1.27, 95% CI: 1.09 to 1.48, p < 0.001) with moderate heterogeneity (I² = 53%). Subgroup analyses revealed a stronger association in studies where the proportion of men was < 45% compared to those ≥ 45% (OR: 1.75 vs. 1.15, p for subgroup difference = 0.01). Studies with lower quality (NOS score = 7) showed a stronger association compared to higher-quality studies (NOS score = 8 or 9, p for subgroup difference = 0.003).</p><p><strong>Conclusion: </strong>This meta-analysis found that prediabetes may be independently associated with an increased risk of periodontitis. Further research is needed to explore the mechanisms underlying this association and potential sex-specific effects.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e411-e421"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bibliometric analysis in Scopus of scientific production on the relationship between periodontitis and gastrointestinal cancer (2014 - 2023).","authors":"A-S Asmat-Abanto, A Portocarrero-Reyes, R-E Espejo-Carrera, C-A Minchón-Medina, D-J Timaná-Palacios","doi":"10.4317/medoral.26969","DOIUrl":"10.4317/medoral.26969","url":null,"abstract":"<p><strong>Background: </strong>Recent studies have suggested that some opportunistic periodontal pathobionts have oncogenic properties. However, few bibliometric studies investigate the relationship between periodontitis and gastrointestinal cancer. This bibliometric study aimed to analyze these epidemiological studies conducted between 2014 and 2023 to guide future research.</p><p><strong>Material and methods: </strong>In March 2024, the Scopus database was explored. The articles selected were subjected to a bibliometric analysis of study designs, trends in annual scientific production, and networks of collaboration among countries. Furthermore, the most outstanding countries, academic institutions, authors and journals with the most significant number of publications and the top most cited articles were analyzed. For this purpose, Microsoft Excel, SPSS and VOSviewer 1.6.20 were used.</p><p><strong>Results: </strong>A total of 123 documents were included for analysis. China contributed the most significant number of publications (33 articles) and the United States had the most significant number of citations (2709). Weimin Ye (h-index:81) and Dominique Michaud (h-index:73) were the most prolific authors (5 articles); Dominique Michaud also had the most citations (470). International Journal of Cancer was the journal with the highest number of articles published (6), in addition to being the publication that had the most citations of these articles (409). Tufts University in the United States had the highest number of citations.</p><p><strong>Conclusions: </strong>Between 2014 and 2023, 123 articles on the relationship between periodontitis and gastrointestinal cancer were published. The largest scientific production was found in China, and the most cited articles were those from the United States. Likewise, the research design most commonly used was the cross-sectional type.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e422-e430"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral side effects of fluoxetine in patients with depressive disorder: A systematic review.","authors":"M-G Sarrión Pérez, Y Jiménez, L Bagán, J Bagán","doi":"10.4317/medoral.26947","DOIUrl":"10.4317/medoral.26947","url":null,"abstract":"<p><strong>Background: </strong>Selective serotonin reuptake inhibitors (SSRIs) are the preferred drugs for treating depression, a condition that has become increasingly prevalent in recent years. Fluoxetine is one of the most widely used SSRIs; however, like other antidepressants, it can cause various systemic and oral adverse effects. This systematic review aimed to analyze the frequency of oral adverse effects associated with fluoxetine compared to other antidepressants.</p><p><strong>Material and methods: </strong>A systematic review was conducted following PRISMA guidelines. A comprehensive literature search was performed in MEDLINE via PubMed, Scopus, The Cochrane Library, and Web of Science, with no date restrictions, including randomized clinical trials and observational studies. The risk of bias was assessed using the Revised Cochrane Risk-of-Bias Tool for randomized trials.</p><p><strong>Results: </strong>A total of 333 articles were identified. After removing duplicates and applying inclusion criteria, 31 randomized clinical trials were selected for analysis. Fluoxetine was primarily compared with tricyclic antidepressants, SSRIs, serotonin-norepinephrine reuptake inhibitors, and other antidepressants. The most frequently reported oral side effect was dry mouth, with prevalence rates ranging from 2.71% to 52.17%, though it was generally lower than with other antidepressants. Dysgeusia was less frequently reported, with only two studies documenting taste alterations. Oral side effects were primarily assessed through subjective patient reports, and no studies incorporated objective salivary flow measurements. Other adverse effects, such as nausea and vomiting, were commonly mentioned, but their potential oral consequences were not evaluated.</p><p><strong>Conclusions: </strong>Fluoxetine is associated with oral side effects, with dry mouth being the most frequently reported. However, data on dysgeusia remain limited, highlighting the need for further research to determine its prevalence. Given the potential impact of dry mouth on oral health and quality of life, future studies should incorporate objective salivary measurements and further investigate the clinical implications of these adverse effects.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e373-e382"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of piezoelectric surgery and conventional techniques in the enucleation of cysts and tumors in the jaws: a systematic review and meta-analysis.","authors":"L Suárez-Pérez, M Peralta-Mamani, R-T Velázquez-Cayón","doi":"10.4317/medoral.26799","DOIUrl":"10.4317/medoral.26799","url":null,"abstract":"<p><strong>Background: </strong>Despite the comprehensive classifications provided by the WHO, the most common lesions include radicular cysts, dentigerous cysts, odontogenic keratocysts, ameloblastomas, and odontomas. The piezoelectric technique has shown effectiveness in removing intraosseous pathologies by relying on ultrasonic microvibrations, which help preserve soft and vascular tissues. Precision in manipulating intraosseous pathology can impact the prognosis and improve the surgical procedure by controlling hemorrhage and promoting microscopic benefits. While previous research has compared the advantages of piezoelectric surgery and rotational methods, a systematic review is needed to consolidate the available information on this specific clinical issue.</p><p><strong>Material and methods: </strong>A search strategy was developed with de PRISMA statement. PubMed, Web of Science, Scopus, and Embase electronic databases were searched. The bibliographic search was conducted in December 2023. The methodological quality of the studies followed the Joanna Briggs Institute (JBI) critical evaluation tool for randomized clinical trials.</p><p><strong>Results: </strong>The final sample comprised 5 clinical trials, involving 231 cysts and 120 tumors in the experimental group. The mean age of participants was 30.6 years, with 196 men and 141 women included in the study. However, conventional surgery is faster than piezosurgery, both techniques exhibited similarities in epithelial perforation, soft tissue damage, edema, postoperative infections, and occurrences of paresthesia. Regarding recurrence, no statistically significant difference was observed between the two techniques (p-value=0.339; 95% confidence interval, -0.093-0.270).</p><p><strong>Conclusions: </strong>The surgical removal of benign odontogenic cysts and tumors in the jaws using piezosurgery yielded slight intraoperative and postoperative advantages compared to conventional rotary surgery, except for the duration of surgical procedures. It shows reduced intraoperative hemorrhage and postoperative pain but similar outcomes in other variables. The results should be interpreted with caution, more studies are needed to obtain a more robust result.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e333-e344"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dimensional changes in buccal cortical bone and lesion volume in teeth with persistent chronic periapical disease subjected to periapical surgery: a cone beam computed tomography study at one year of follow-up.","authors":"A Boronat-López, J-C Bernabeu-Mira, M Peñarrocha-Diago, M Peñarrocha-Diago, D Peñarrocha-Oltra","doi":"10.4317/medoral.27006","DOIUrl":"10.4317/medoral.27006","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate changes in buccal cortical bone and lesion volume in teeth with persistent periapical disease one year after periapical surgery using cone-beam computed tomography (CBCT).</p><p><strong>Material and methods: </strong>A prospective study was conducted involving patients with persistent periapical disease undergoing periapical surgery, with one year of follow-up. Data collected included patient age, gender, teeth involved, and the number of roots/lesions. CBCT measurements were taken preoperatively and one year post-surgery, including the distance from the cementoenamel junction to the buccal bone crest (CEJ-BBC), marginal bone loss, buccal cortical height, presence of fenestration, apical depth, cortical bone width at 1, 3, and 5 mm from the buccal bone crest, and lesion volume in mm³. Success was assessed using the \"Modified Penn 3D criteria.\"</p><p><strong>Results: </strong>The study included 92 patients with 111 roots exhibiting persistent chronic periapical lesions. Statistically significant changes were observed in all buccal cortical bone parameters one year after surgery. The CEJ-BBC distance increased, indicating a marginal bone loss of 0.23 mm. Notably, the height from the buccal cortical bone crest to the lesion, apical depth, buccal bone thickness, the number of fenestrations, and lesion volume decreased (91.1%). Buccal cortical bone thickness was a predictor of volume reduction, showing a significant relationship at T1 between greater thickness and smaller volume variation. Patient age and gender did not significantly influence these changes. Fenestrations and larger lesion volumes correlated with reduced healing probabilities. The overall success rate was 88%, with tooth position and root involvement impacting healing outcomes.</p><p><strong>Conclusions: </strong>One year post-surgery, buccal cortical bone showed no clinically relevant changes, while lesion volume decreased by 91.1%, more significantly in anterior teeth. Greater buccal cortical bone width was associated with smaller volume reduction. A larger lesion volume and presence of fenestrations adversely affected healing rates.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e469-e475"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severity, extent, distribution and predisposing factors of gingival recession in Turkish patients: a cross-sectional study.","authors":"H Çelik, H-S Güngörmek","doi":"10.4317/medoral.26956","DOIUrl":"10.4317/medoral.26956","url":null,"abstract":"<p><strong>Background: </strong>The aim of this cross-sectional study was to assess the extent, severity, distribution and potential predisposing factors of gingival recession (GR), utilizing a questionnaire and clinical periodontal measurements obtained from Turkish patients.</p><p><strong>Material and methods: </strong>A total of 534 subjects were examined. Participants meeting the inclusion criteria evaluated by dental hygiene habits, educational level, smoking habit and past orthodontic treatment. Plaque index (PI), gingival index (GI), probing depth (PD), bleeding on probing (BOP), clinical attachment level (CAL), gingival thickness (GT), high frenum attachment, and mobility were recorded on the tooth with GR. Probe transparency (PT), crown width/crown length ratio (CW/CL), papilla height (PH) and height of gingival scallop were measured on the index tooth (#11FDI). The GR severity was categorized by using Miller's classification.</p><p><strong>Results: </strong>Of the 534 individuals examined in this study, 376 (70.4%) had gingival recession, while 262 patients (49%) were meeting the inclusion criteria and 2,721 teeth (37%) were affected. The majority of the teeth (44.8%) showed Miller class I. The highest GR frequency was detected in incisors (39.5%), particularly in mandible. The correlation between GR and PI (p=0.025), PD (p=0.034), PH (p=0.007), CW/CL (p=0.009), CAL (p<0,001), PT (p<0,001) was found statistically significant. No statistical relation was found between tooth brushing duration (p>0,05), tooth brushing frequency (p>0,05) and gingival recession.</p><p><strong>Conclusions: </strong>Gingival recession is a multifactorial condition significantly influenced by clinical and anatomical parameters such as PI, PH, CW/CL, PT while toothbrushing habits, including duration and frequency, appear to have a minimal impact.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e401-e410"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periapical radiographs vs cone beam CT imaging for the evaluation of peri-implant bone defects: an ex vivo study.","authors":"N-G Tzortzakis, S Damaskos, K Dimakopoulou, E Chatzipetros, C Angelopoulos","doi":"10.4317/medoral.26777","DOIUrl":"10.4317/medoral.26777","url":null,"abstract":"<p><strong>Background: </strong>Data on the radiographic interpretation of peri-implantitis is still controversial. Thus, our study aimed to: a) investigate the detectability rate of ex-vivo induced peri-implant bone defects (PBDs) between observers using two different imaging methods; Cone Beam Computed Tomography (CBCT) and Periapical Radiographs (PAs), b) investigate the observers' agreement on their ability to detect PBDs according to their level of expertise and, c) determine the sensitivity and specificity of the imaging methods used to detect induced PBDs.</p><p><strong>Material and methods: </strong>Two dried human mandibles were used in which ten dental implants were placed and eight PBDs were created simulating clinical conditions. Radiographic examination using PAs and two CBCT modes [CBCT/N (normal/0.3mm3), and CBCT/HR (HiRes/0.15mm3)] was performed at all experimental stages. All PBDs were recorded for their dimensions using a dental periodontal probe as they were used as a gold standard (GS). Finally, 145 images (49 PAs, 48 CBCT/N, and 48 CBCT/HR) were created and evaluated by nine independent observers. Three oral radiologists (OR), three implantologists (IS), and three general practitioners (GP).</p><p><strong>Results: </strong>PBDs were detected at a higher rate by ORs compared to ISs, and GPs. However, the rate of their agreement, did not reach the nominal level of significance (z-test p-value> 0.05), and also between observers of the same expertise, and between the different imaging methods used: CBCT and PAs (z-test p-value> 0.05). In total, the sensitivity of the CBCTs and PAs method was 95% and 80.5%, respectively. While the specificity for all methods was lower, 57%, 62.2% and 50.4% for CBCT/N, CBCT/H and PAs methods, respectively.</p><p><strong>Conclusions: </strong>Although CBCT performs better than PAs in ex-vivo induced PBDs, further research is needed to evaluate if the present results can be extrapolated to other clinical scenarios and defect configurations.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e322-e332"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between rheumatoid arthritis and periodontitis: a study based on a two-sample mendelian randomisation analysis.","authors":"Q Cai, C Li, Z Quan, X Yang, T Chen, X Han, X Xu","doi":"10.4317/medoral.26848","DOIUrl":"10.4317/medoral.26848","url":null,"abstract":"<p><strong>Background: </strong>The association between Rheumatoid arthritis (RA) and Periodontitis (PD) has been increasingly recognised, yet traditional epidemiological studies face challenges in establishing associations. Therefore, this study aims to genetically assess the association between RA and PD through Mendelian randomisation (MR) analysis, using genetic variations as instrumental variables.</p><p><strong>Material and methods: </strong>Data on RA and PD were downloaded from the EBI website. The RA data contained 8,255 cases and 409,001 controls, with a total of 24,175,266 SNPs; the chronic PD data contained 950 cases and 409,001 controls, with a total of 11,842,647 SNPs; the acute PD data contained 128 cases and 456,220 controls, with a total of 11,842,647 SNPs. Additionally, the potential association between RA and PD was investigated. The intercept between Mendelian randomisation (MR)-Egger regression, MR-PRESSO test results and funnel plots was used to analyse the horizontal pleiotropy of SNPs along with the effect of individual SNPs on inverse-variance weighting (IVW) analysis results, assessed using the leave-one-out method.</p><p><strong>Results: </strong>In total, 26 SNPs highly associated with RA were screened; MR-Egger regression (OR=1.242, 95% CI (1.032-1.494), P=0.031), WM (OR=1.190, 95% CI (1.015-1.395), P=0.032), IVW (OR=1.191, 95% CI (1.053-1.348), P=0.006) and weighted mode (OR=1.212, 95% CI (1.043-1.409), P=0.019) suggested that RA was a likelihood factor for chronic PD, whereas RA was not associated with the incidence of acute PD, and the Cochran's Q test indicated no statistical heterogeneity between SNPs highly associated with RA. Moreover, analyses using the intercept between the MR-Egger regression, MR-PRESSO test results and funnel plot revealed no horizontal pleiotropy in SNPs highly associated with RA.</p><p><strong>Conclusions: </strong>Rheumatoid arthritis was genetically identified as a likelihood factor for PD and the onset of chronic PD, but no association was observed between RA and acute PD.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e354-e362"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing nerve injuries in oral surgery: a survey-based study on prevention and management.","authors":"N Agbulut","doi":"10.4317/medoral.26995","DOIUrl":"10.4317/medoral.26995","url":null,"abstract":"<p><strong>Background: </strong>Understanding and mitigating iatrogenic nerve injuries, specifically IAN and LN, is crucial in the field of oral and maxillofacial surgery. These injuries may lead to profound sensory deficits, pain syndromes, and impaired quality of life for patients. This study aims to assess the prevention and management practices for inferior alveolar nerve and lingual nerve injuries among dental professionals. By gathering data through a survey, the study seeks to evaluate current experiences, awareness, and protocols, ultimately contributing to improved guidelines for nerve injury management.</p><p><strong>Material and methods: </strong>This cross-sectional study utilized an online survey distributed via Turkish Dental Association to registered dentists and specialists. The predictor variables were the procedure types associated with nerve injuries. The main outcome variables were preventive measures and patient management strategies. Demographic profiling including age, years in profession, specialty, and type of current workplace were determined as covariates.</p><p><strong>Results: </strong>1477 respondents provided complete answers, with questions addressing demographics, nerve injury incidents, preventive measures, and management strategies. The most reported IAN and LN injuries were linked to dental implant surgery (n=1067), mandibular third molar surgery (n=958), and local anesthesia applications (n=459). Interestingly, more than 30% of participants reported no experience with nerve injuries. For preventive measures in tooth extraction, 281 respondents performed coronectomies, and in implant surgery over 80% of the participants evaluated tomographic images in high-risk cases. Most common management strategies for paresthesia included vitamin B12 (n=1093) and NSAIDs (n=1051). The use of gabapentin, and non-medical treatments like biofeedback and alternative therapies were rarely employed.</p><p><strong>Conclusions: </strong>The survey revealed a diverse range of practices regarding nerve injury prevention and management, emphasizing the need for evidence-based approaches and consensus guidelines. Understanding current practices for managing IAN and LN injuries can inform future guidelines, reduce complications, and improve patient outcomes in oral and maxillofacial surgery.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e462-e468"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}