Medicina Oral Patologia Oral Y Cirugia Bucal最新文献

{"title":"Comparison between different intermaxillary fixation systems in the surgical and orthopedic treatment of non-condylar mandibular fractures. Systematic review.","authors":"M-J Mancilla, M-A Lemus, P-T Contreras","doi":"10.4317/medoral.27264","DOIUrl":"https://doi.org/10.4317/medoral.27264","url":null,"abstract":"<p><strong>Background: </strong>The treatment of mandibular fractures can be orthopedic and/or surgical; in both modalities, intermaxillary fixation is a therapeutic tool that allows for the stabilization and reduction of fractures, guiding dental occlusion There are different methods of intermaxillary fixation, each with individual characteristics that provide therapeutic options for the practitioner. This study aims to perform a quantitative and qualitative comparison of different features of these intermaxillary fixation systems through a systematic review.</p><p><strong>Material and methods: </strong>A systematic review was performed, following the PRISMA guidelines. The Pubmed, SCOPUS, Web of Science and Cochrane databases were searched. Several variables were considered and are presented comprehensively in tables and figures. The initial literature search resulted in 51 articles, of which 9 met the inclusion criteria for the analysis.</p><p><strong>Results: </strong>Of the 51 identified articles, 28 were analyzed, with 19 excluded after full-text evaluation. Ultimately, 9 studies with 3,221 patients were included, comparing Erich arch bars (EAB), hybrid arch bars (HAB), and intermaxillary fixation screws (IMFS).</p><p><strong>Discussion: </strong>The studies focused on simple fractures with sufficient teeth for orthopedic treatment, excluding isolated maxillary fractures. Results showed differences in installation time, occlusal stability, oral hygiene, and costs, with EAB being the most expensive. Patient quality of life and complications, such as screw loss and root perforations, were also evaluated. Most studies presented a low risk of bias.</p><p><strong>Conclusions: </strong>Screw-based methods like IMFS and HAB offer shorter installation times than EAB, reducing surgery duration, costs, and biosecurity risks. While EAB remains a valid option, screw methods provide advantages in time, hygiene control, and biosecurity, with the choice depending on patient needs and surgical experience.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144152469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between periodontitis and proteinuria in chronic kidney disease: A review.","authors":"G Zhu, L Chen, Q Liu","doi":"10.4317/medoral.27304","DOIUrl":"https://doi.org/10.4317/medoral.27304","url":null,"abstract":"<p><strong>Background: </strong>Proteinuria is elevated protein in the urine possibly progressing to glomerular sclerosis, which was frequently observed in chronic kidney disease (CKD), diabetes, preeclampsia, etc. Previous studies have revealed that periodontitis and these diseases share common risk factors, so a study is necessary to discuss the potential relationship between periodontitis and proteinuria. For the moment, there are no reports that are concerned about the correlation between periodontitis and proteinuria.</p><p><strong>Material and methods: </strong>We searched PubMed for studies associated with periodontitis and proteinuria published before March 2025.</p><p><strong>Results: </strong>Existing evidence showed that periodontitis might increase the risk of proteinuria, as periodontal pathogens and periodontal inflammatory reactions were proven to injure the glomerulus and renal tubules contributing to the progression of proteinuria. On the other way, proteinuria might affect systemic inflammation and bone metabolism to increase the risk of periodontitis.</p><p><strong>Conclusions: </strong>This article reviews the relationship between periodontitis and proteinuria, reveals their predictable potential for chronic kidney injury, and makes recommendations for the treatment of periodontitis and proteinuria.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144152557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic litectomy: optimizing the management of sialolithiasis.","authors":"F Almeida-Parra, Á Ranz-Colio, Á Bueno-de-Vicente, C Cárdenas-Serres, P de Leyva-Moreno, J Acero-Sanz","doi":"10.4317/medoral.26992","DOIUrl":"10.4317/medoral.26992","url":null,"abstract":"<p><strong>Background: </strong>Sialolithiasis of the salivary glandular complex appears with high frequency in the major salivary glands. The most affected salivary gland is the submandibular gland, followed by the parotid and sublingual glands. The treatment of this disease by endoscopic litectomy has reduced the need of adenectomy.</p><p><strong>Material and methods: </strong>We reviewed retrospectively a series of 77 patients who had salivary gland stones between January 2020 and January 2024. Inclusion criteria for endoscopic treatment was lithiasis smaller than 8 mm. Follow-up was performed at a week, one month and three months after the surgery by clinical examination with a mean follow-up of 17 months and CT in selected cases.</p><p><strong>Results: </strong>Treatment was successful in 69 cases, while in 8 patients the treatment failed, with a successful extraction of the stone in 89.61% of patients. A total of 74 stones were removed from 69 patients. The mean stone size was 6.68 mm (range 3 to 8 mm), located mainly in hilum (n=61, 75.60%), median duct (n=14, 17.07%) and retrocaruncular (n=6, 7.31%). Adenectomy, due to failure of the procedure, was performed in 10 patients, 7 in patients due to lack of recovery of the sialolith and in 3 patients due to postoperative stenosis after removal of the sialolith. Complications involved 6 patients with the presence of stenosis after the lithectomy procedure, in 3 patients it was resolved with endoscopic dilation and in the other 3 an adenectomy was necessary.</p><p><strong>Conclusions: </strong>Minimally invasive intraoral surgery has high success rate, contributes to reduce the need for glandular radical surgery with a low rate of severe complications.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e456-e461"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epithelial salivary gland neoplasms in pediatric patients: A comprehensive review.","authors":"M-E Pérez-de-Oliveira, S-S Sousa-Neto, P-A Vargas","doi":"10.4317/medoral.26983","DOIUrl":"10.4317/medoral.26983","url":null,"abstract":"<p><strong>Background: </strong>Salivary gland tumors (SGTs) are a rare group of neoplasms in pediatric patients, characterized by diverse histological subtypes and distinct biological behaviors. This manuscript aims to provide a comprehensive overview of the demographic, clinical, and histopathological characteristics of SGTs in this population, with the goal of enhancing understanding of their presentation and implications for treatment.</p><p><strong>Material and methods: </strong>An updated descriptive literature review was performed to identify studies reporting the clinicopathological features of epithelial SGTs in pediatric patients.</p><p><strong>Results: </strong>SGTs in pediatric patients are slightly more prevalent in females and typically arise during the second decade of life. The parotid gland is the most commonly affected site for both benign and malignant tumors, which usually present as an asymptomatic mass. Pleomorphic adenoma and mucoepidermoid carcinoma are the most frequently observed entities. Surgical intervention remains the primary treatment modality, and the overall prognosis is generally favorable.</p><p><strong>Conclusions: </strong>This review highlights that SGTs in pediatric patients present distinct clinical features and prognostic outcomes compared to adults. Although they are rare in this age group, clinicians should remain vigilant to these neoplasms when assessing nodular masses in both major and minor salivary glands.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e440-e445"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The interaction between third molars and surrounding periapical tissues in mandibular stress distribution during high-impact trauma: a finite element study.","authors":"C-B Nogueira, F-W Costa, F-S Carvalho, T-P Bezerra, I-C Neto, F-I Júnior, E-C Soares","doi":"10.4317/medoral.26954","DOIUrl":"10.4317/medoral.26954","url":null,"abstract":"<p><strong>Background: </strong>The presence of mandibular third molars has been associated with the risk of mandibular fractures, highlighting the need for comprehensive studies considering the interaction with other mandibular structures. This study investigates how mandibular third molars and neighboring tissues can influence the structural fragility of the mandible using finite element analysis.</p><p><strong>Material and methods: </strong>A finite element analysis study following the guidelines proposed by RIFEM 1.0 was performed using three previously created mandible models: Model A, without right and left third molars; Model B, without one third molar; Model C, with bilateral presence of third molars. A 2452N force was applied to the right mandibular body in a virtual environment, allowing for a structural analysis of each mandible.</p><p><strong>Results: </strong>Models without third molars and with only one third molar showed similar energy dissipation patterns, contrasting with the model with both third molars. The presence of third molars influenced the magnitude and distribution of stress, highlighting fragility points in specific areas such as the lingual surface, the condyles bilaterally (models without and with one contralateral third molar to trauma), and the distal cervical region of the second molar (third molar absent), as well as significantly showed the path of energy towards the contralateral side of the trauma with a concentration of energy at the contact points of virtually all teeth present immediately after impact.</p><p><strong>Conclusions: </strong>The presence of mandibular third molars influenced the distribution and magnitude of stress within the mandible during a simulated high-impact trauma. Models with third molars exhibit distinct stress patterns, with fragility points appearing in critical areas such as the lingual surface, condyles, and second molar regions. These findings suggest that the presence of third molars increases the structural fragility of the mandible, potentially elevating the risk of mandibular fractures, especially in the context of traumatic impacts.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e394-e400"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotional states in patients with cancer or with suspected oral potentially malignant disorders: a cross-sectional study in an oral medicine setting.","authors":"M Bazzano, R Mauceri, G Marcon, M Coppini, D Montemaggiore, G Campisi","doi":"10.4317/medoral.26989","DOIUrl":"10.4317/medoral.26989","url":null,"abstract":"<p><strong>Background: </strong>This cross-sectional study aims to investigate the emotional states (i.e., anxiety, depression, and stress) of 4 distinct groups of patients attending an Oral Medicine setting.</p><p><strong>Material and methods: </strong>four distinct subgroups of patients have been enrolled: 25 patients with OSCC (OSCC group); 25 patients with other solid tumor (ONCO group), 25 cancer patients with MRONJ (MRONJ group), 25 patients with oral potentially malignant disorder (OPMD group). Standardized assessment tools (i.e. Beck Depression Inventory (BDI) and Depression Anxiety Stress Scales-21 (DASS-21) questionnaires) were utilized to evaluate the patients' emotional states.</p><p><strong>Results: </strong>Among the 100 patients enrolled, 59% of whom were female, and most patients were aged between 70 and 80 years. The mean total BDI score was 16.57, and the mean total DASS-21 score was 15.32. The mean scores of the OSCC group showed moderate depression, all the other groups were classified as mild depression. The OPMD group showed a significantly higher level of anxiety.</p><p><strong>Conclusions: </strong>Patients in the oral medicine setting may face various diseases and may develop emotional states that affect their treatment adherence. For effective management of these emotional states, the presence of a multidisciplinary team, including a psychologist, and the adoption of individualized approaches, seem to be necessary.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e446-e455"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"State of knowledge of the relationship between celiac disease and oral pathology: A scoping review.","authors":"R Martín-Masot, P Ramos-García, E Torcuato-Rubio, M-I Pérez-Gaspar, V-M Navas-López, M-Á González-Moles, T Nestares","doi":"10.4317/medoral.26950","DOIUrl":"10.4317/medoral.26950","url":null,"abstract":"<p><strong>Background: </strong>Celiac disease (CD) is a systemic disorder characterized by an enteropathy of highly variable clinical expression, in which the relationship with oral pathology has not yet been fully elucidated. We aimed to update the current knowledge on oral manifestations in CD, to identify evidence gaps and to point out future research lines.</p><p><strong>Material and methods: </strong>PRISMA-ScR guidelines were followed. MEDLINE/PubMed, Embase, Web of Science and Scopus were searched for primary-level observational studies to analyze the prevalence of oral pathology in CD patients, without language or publication date restrictions.</p><p><strong>Results: </strong>We included 107 studies, encompassing a total of 26148 celiac patients and 36063 controls. Our results point to several oral pathologies with higher prevalence in CD patients than in healthy controls, most notably recurrent aphthous stomatitis (RAS)(n=69 studies/12606 celiac patients), developmental enamel defects (n=61 studies/5037 patients), dental caries (n=33 studies/2730 patients), delayed eruption (n=12 studies/1062 patients), atrophic glossitis (n=10 studies/1062 patients), angular cheilitis (n=7 studies/10606 patients), gingivo-periodontal diseases (n=7 studies/1122 patients), and Sjögren's syndrome (n=5 studies/953 patients).</p><p><strong>Conclusions: </strong>CD is frequently associated with oral pathologies, including RAS, dental caries, gingivitis, decreased salivary flow, dental enamel defects and some relevant autoimmune processes, such as oral lichen planus and probably Sjögren's syndrome.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e383-e393"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical behavior of two-piece zirconia implants. A systematic review.","authors":"S Bazal-Bonelli, M Castro-Janeiro, J Ríos-Barbero, M Cano Sánchez de Tembleque, J López-Quiles, C Meniz-García, J Cortés-Bretón Brinkmann","doi":"10.4317/medoral.26752","DOIUrl":"10.4317/medoral.26752","url":null,"abstract":"<p><strong>Background: </strong>This systematic review aimed to evaluate the clinical behavior of two-piece zirconia implants (T-PZI) in terms of overall implant survival and success rates, marginal bone loss (MBL) complication rates, and others biological parameters.</p><p><strong>Material and methods: </strong>PRISMA guidelines were followed, and the review was registered in the International Prospective Register of Systematic Reviews (PROSPERO). An automated search was conducted in four databases (Medline/PubMed, Scopus, Web of Science, and Cochrane Library), as well as a manual search for relevant clinical articles published until 18 May 2024. The review included human studies with at least five patients in which T-PZI were placed. Quality of evidence was evaluated using the Newcastle-Ottawa Quality Assessment Scale and the Cochrane risk-of-bias tool for randomized trials version 2 (RoB 2).</p><p><strong>Results: </strong>Six studies met the inclusion criteria and were included for analysis, with a total of 298 T-PZI. A survival rate of 96.31% was recorded with follow-up periods ranging from 18.4±10.4 months to 111.1±2.2 months. The success rate ranged from 63 to 100% and MBL ranged from 0.130.6 to 1.38±0.81mm Conclusions: T-PZI may offer a reliable alternative to titanium dental implants, achieving a survival rate of 96.31%, acceptable rates of MBL and adequate biological parameters. However, the findings of the review must be treated with caution, as the data obtained are derived from the early stages of this new development in ceramic dental implants. More comparative studies are needed in order to determine the viability of T-PZI in different clinical situations.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e313-e321"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of platelet-rich-fibrin for the treatment of alveolar osteitis: a systematic review and meta-analysis.","authors":"C Ávila-Oliver, V Veloso, G Laissle, A-M Rojas, F Verdugo-Paiva, J Ramos-Rojas","doi":"10.4317/medoral.26801","DOIUrl":"10.4317/medoral.26801","url":null,"abstract":"<p><strong>Background: </strong>This systematic review aims to provide an updated summary of the available evidence on the role of platelet-rich fibrin (PRF) in the treatment of alveolar osteitis.</p><p><strong>Material and methods: </strong>Searches were conducted in several electronic databases, including PubMed, EBSCO, Cochrane Central Register of Controlled Trials (CENTRAL) LILACS and ClinicalTrials.gov. No date or language restrictions were applied. Two reviewers independently evaluated eligible studies according to predefined criteria and extracted data using a standardized form. Meta-analyses were performed to estimate results and the certainty of evidence, using the GRADE approach, was assessed.</p><p><strong>Results: </strong>The search strategy yielded 1.706 references. Finally, 4 randomized trials were included and assessed quantitatively. Overall, the risk of bias was low for 75% of the domains reviewed across studies. The studies included a total of 179 patients, where the intervention group received PRF, and the control group received several treatment alternatives, including iodoform gauze, zinc oxide eugenol, and saline solution. Results showed that the use of PRF may decrease pain severity measured on day 3 (MD -1.66, CI 95%, -4.11 to 0.78) and on day 7 (MD -1.57, CI 95%, -4.00 to 0.88), and improves alveolar socket healing (SMD 2.25; 95% CI 1.70 to 2.80; p<0.00001; I2=12%).</p><p><strong>Conclusions: </strong>The results of this study demonstrate that PRF improves alveolar healing, reduces analgesic use in patients, and likely increases overall clinical efficacy, making it a valuable alternative in the treatment of alveolar osteitis. Despite these findings, this review also showed a great degree of uncertainty on the impact of PRF on pain severity associated with alveolar osteitis. Although these results are promising, further randomized clinical trials with standardized methodologies must be performed to validate these findings.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e345-e353"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of ozone therapy on postoperative pain, swelling, and trismus caused by surgical extraction of unerupted lower third molars: a double-blinded split-mouth randomized controlled trial.","authors":"R-B Almeida, F-U Campos, J-C Ramacciato, D-C Peruzzo, G-V Fernandes, J-C Joly, M Sperandio","doi":"10.4317/medoral.26974","DOIUrl":"10.4317/medoral.26974","url":null,"abstract":"<p><strong>Background: </strong>Third molar extraction surgery is a common procedure, but it results in pain, swelling, and trismus. Ozone therapy (Oz) has emerged as a viable option for pain control and as an option to limit bacterial growth, improving the wound healing. Then, this randomized controlled trial aimed to evaluate the effectiveness of adjunctive use of ozone therapy (OzT) in managing pain, swelling, and trismus after lower third molar removal.</p><p><strong>Material and methods: </strong>A split-mouth design was selected, enrolling 60 patients. There were 2 groups (Sham and OzT). The same surgeon performed all procedures. The pain was evaluated using the VAS scale and the number of paracetamol tablets taken. The quality of life was assessed using the OHIP-14 questionnaire. The data were statistically evaluated.</p><p><strong>Results: </strong>120 surgical procedures were performed on 60 participants (34 males [56%] and 26 females [44%]). Regarding the number of paracetamol tablets taken, the test group had a significantly lower consumption (p<0.002). In addition, the test group presented a significantly lower pain score on days 1, 3, and 5 postoperatively, with no difference between groups on the 7th day (p<0.0145). Both sides presented postoperative edema, which regressed from day 5 (no significant difference). A similar case scenario was observed for mouth opening. OzT impacted the patient's quality of life (OHIP-14, p<0.05), favoring ozone therapy.</p><p><strong>Conclusions: </strong>The results demonstrated that OzT is an effective adjunctive strategy for reducing postoperative pain following the extraction of lower third molar teeth.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e431-e439"},"PeriodicalIF":1.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}