Medicina Oral Patologia Oral Y Cirugia Bucal最新文献

{"title":"Novel topical dressing for dry socket and comparison of its efficacy with that of Alvogyl®: A randomized controlled clinical trial.","authors":"K Famili, M Gholami, A Shahri","doi":"10.4317/medoral.26820","DOIUrl":"10.4317/medoral.26820","url":null,"abstract":"<p><strong>Background: </strong>To evaluate the efficacy of a novel topical dressing (composed of triamcinolone, ground Dianthus caryophyllus, eugenol, honey, and Iris germanica) for alveolar osteitis (dry socket) against Alvogyl® (composed of eugenol, butamben, and iodoform).</p><p><strong>Material and methods: </strong>In a randomized parallel-armed clinical trial at Mashhad Dental School's Department of Oral and Maxillofacial Surgery, 36 patients with alveolar osteitis were randomly allocated into two groups according to the inclusion criteria (n=18), using sealed envelopes: one receiving a novel topical dressing and the other receiving Alvogyl®. Post-treatment pain was assessed using a visual analog scale immediately after the procedure and at 30 and 60 minutes, 24, 48, 72, and 96 hours, and one week later, as well as the frequency of dressing applications and analgesic usage. Data analysis was performed using SPSS version 26.</p><p><strong>Results: </strong>Analyses were completed on all 36 participants without dropouts. No significant age or gender differences were found between the groups at baseline (p=0.370 and p=0.502, respectively). The novel dressing group experienced significantly lower pain scores at 30 and 60 minutes post-treatment (p<0.001), but higher scores at 24 (p=0.029), 48 (p=0.001), and 72 (p=0.017) hours, and similar pain scores immediately after the procedure and at 96 hours and 1 week (p>0.05), compared to the Alvogyl® group. The mean number of analgesics taken (p=0.097) and the mean frequency of dressing application (p=0.839) were not significantly different between the two groups.</p><p><strong>Conclusions: </strong>The novel topical dressing demonstrated efficacy comparable to Alvogyl®, with the added benefits of cost-effectiveness and the absence of side effects, suggesting its potential as an alternative treatment for dry socket.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e41-e48"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801677/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective clinical follow-up of implants placed in edentulous jaws after computer-guided surgery and immediate loading, in geriatric patients.","authors":"L Monsalve-Guil, E Velasco-Ortega, I Ortiz-Garcia, N Matos-Garrido, J Moreno-Muñoz, E Núñez-Márquez, J-L Rondón-Romero, J López-López, Á Jiménez-Guerra","doi":"10.4317/medoral.26837","DOIUrl":"10.4317/medoral.26837","url":null,"abstract":"<p><strong>Background: </strong>Although there are many works analyzing the clinical behavior of immediate loading of implants inserted by guided surgery, the literature referring specifically to elderly patients is scarce. The aim of this investigation is to present the clinical outcomes of immediate loading of implants inserted by guided surgery in geriatric patients with edentulous maxilla.</p><p><strong>Material and methods: </strong>The clinical data of 20 elderly patients with edentulous jaws are analyzed retrospectively. All were diagnosed with cone beam computed tomography, oral examination, and articulator-mounted models to analyze the intermaxillary relationship. They were treated with 4 to 10 implants by flapless guided surgery with immediate loading. After surgery, the implants were loaded with a temporary acrylic prosthesis and six months later, a definitive full-arch ceramic prosthesis was placed.</p><p><strong>Results: </strong>Twenty patients with an average age of 68.8 years (11 males and 9 females) underwent treatment with a total of 139 implants. Among them, 15 patients (75%) had a history of periodontitis. Ten patients (50%) smoked. Thirteen patients (65%) report a history oof systemic disease. The mean follow-up was 53.1 ± 21.4 months. The clinical outcomes indicated a 100% success rate for the implants. Twenty full-arch fixed maxillary rehabilitations were performed, with an average marginal bone loss of 1.37 mm (S.D. 0.53 mm.) Marginal bone loss was significantly greater for patients with a longer period of clinical follow-up. Peri-implantitis is reported in 17 implants (12.2%) in 8 patients (40%). Four patients (20%) showed some kind of mechanical prosthodontic complications.</p><p><strong>Conclusions: </strong>The present work indicates that treatment with implant-supported fixed full-arch prostheses, in geriatric patients with edentulous jaws and through guided surgery and immediate loading, this implant protocol seems to be a successful.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":"30 1","pages":"e76-e85"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attitude of general dental practitioners, oral surgeons, and dentistry students towards oral lesions and oral biopsy.","authors":"V Schiavo-Di Flaviano, B González-Navarro, C Martín Carreras-Presa, E Jané-Salas, J López-López","doi":"10.4317/medoral.26804","DOIUrl":"10.4317/medoral.26804","url":null,"abstract":"<p><strong>Background: </strong>Oral biopsy is a fundamental surgical procedure used to obtain a histopathological result that assists clinicians in establishing a definitive diagnosis of oral mucosal lesions. The aim of this study was to asses the knowledge and attitudes of dental students, general dentists, and oral surgery experts regarding the detection of oral lesions and the use of biopsy as a diagnostic tool.</p><p><strong>Material and methods: </strong>a self-administered questionnaire consisting of 26 questions and 3 clinical cases on oral lesions was distributed to general dentists, oral surgery specialists and final-year dentistry students at the University of Barcelona. A descriptive analysis of all variables included was performed. The chi-square test was used to compare categorical variables, and a multivariate logistic regression model was performed.</p><p><strong>Results: </strong>A total of 281 questionnaires were included in the study. In terms of diagnosing of oral lesions, 44.7% of students and 32.1% of general dentists were unable to make an accurate diagnosis, compared to 81.7% of specialists. Twelve students (15.8%) and twenty general dentists (14.9%) reported lacking the skills to perform a biopsy. Ninety general dentists (67.2%) reported feeling uncomfortable performing biopsies due to a lack of experience. Oral surgeons are 84.4 times more likely to identify lesions of the oral mucosa compared to students. General dentists experience 9.6 times more difficulty diagnosing oral lesions compared to students. General dentists are 0.43 times less likely to perform sample analysis compared to students.</p><p><strong>Conclusions: </strong>Oral biopsy is a procedure primarily performed by specialists in oral surgery, with its use among general dentists being limited, likely due to a lack of training in the field. To encourage the use of biopsy among general dentists, clinical training should be a fundamental component of the education of oral healthcare providers.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e31-e40"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive anaesthesia management strategies for orthognathic surgical procedure.","authors":"B Tapia-Salinas, I Aragón-Niño, J-L Del-Castillo-Pardo-de-Vera, J-L Cebrián-Carretero","doi":"10.4317/medoral.26833","DOIUrl":"10.4317/medoral.26833","url":null,"abstract":"<p><strong>Background: </strong>Orthognathic surgery is commonly performed to correct malocclusion and facial asymmetry, typically in young and healthy patients. However, it's crucial to recognize that facial deformities can also be features of various syndromes, complicating the surgical and anesthetic management.</p><p><strong>Material and methods: </strong>This review examines the key factors influencing anaesthesia management in orthognathic surgery patients. The perioperative care process was analyzed, focusing on the surgical procedure, airway management, and anaesthesia techniques. Additional factors considered include bleeding control, postoperative nausea and vomiting (PONV), antibiotic prophylaxis, analgesia, and deep venous thrombosis (DVT) prevention.</p><p><strong>Results: </strong>The review highlighted the critical role of comprehensive anaesthesia management in determining the outcomes of orthognathic surgery. Proper airway management, effective bleeding control, and the prevention of PONV and DVT were identified as significant factors in optimizing patient recovery. The use of protocols and a multidisciplinary approach were emphasized as essential in minimizing complications and improving postoperative outcomes.</p><p><strong>Conclusions: </strong>Comprehensive and carefully planned anesthesia management is vital for the success of orthognathic surgery. Employing a multidisciplinary approach and adhering to established protocols can enhance patient outcomes and expedite recovery, especially in cases involving complex syndromic patients.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e56-e64"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Malignant transformation of oral lichen planus: where are we now?","authors":"M-Á González-Moles, P Ramos-García","doi":"10.4317/medoral.26834","DOIUrl":"10.4317/medoral.26834","url":null,"abstract":"<p><strong>Background: </strong>Oral lichen planus (OLP) is a very prevalent disease whose main clinical feature is the appearance of white hyperkeratotic reticular lesions, which may or may not be accompanied by erosive and/or atrophic lesions, among others. One of the most relevant aspects of the process is its current consideration as an oral potentially malignant disorder (OPMD), although this is currently the subject of considerable controversy.</p><p><strong>Material and methods: </strong>A review of the literature was carried out in order to critically analyze the controversies surrounding the consideration of OLP as an OPMD, where they originate from and the available evidence that has led to the conclusion that OLP patients are at risk of developing oral cancer.</p><p><strong>Results: </strong>The controversies over the definitive acceptance of OLP as an OPMD were classified as controversies related to the lack of widely accepted diagnostic criteria for OLP; controversies related to histopathological aspects of OLP and the presence of epithelial dysplasia as a diagnostic exclusion criterion; and controversies related to clinical aspects of OLP (which in turn were subclassified into: controversies on how to interpret reticular lesions in OLP, on the nature of the white plaques that appear in OLP; on the changing character of reticular lesions in OLP; and on the criteria for accepting a case as a true malignant OLP). Furthermore, evidence to justify the acceptance of OLP as an OPMD was in depth reviewed, including the molecular evidence, evidence from research studies with the highest evidence design -systematic reviews and meta-analyses-, and evidence from case series reporting strong results.</p><p><strong>Conclusions: </strong>This paper presents the reasons for the controversies as well as the evidence that allows us to accept that OLP behaves as an OPMD.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e65-e75"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of normocalcemic primary hyperparathyroidism in bone density alterations of the jaws in patients with periodontitis.","authors":"S García-Rueda, C-F Márquez-Arrico, A Herrero-Babiloni, J Silvestre-Rangil, F-J Silvestre","doi":"10.4317/medoral.26958","DOIUrl":"10.4317/medoral.26958","url":null,"abstract":"<p><strong>Background: </strong>Normocalcemic Primary Hyperparathyroidism (NPHPT) is a complex syndrome that causes excess secretion of parathyroid hormone (PTH) from the parathyroid glands. PTH in bone activates the function of osteoclasts, to increase bone resorption and thus increase plasma calcium levels. Given that periodontitis generates osteolytic lesions and has a high prevalence in adults, both pathologies could share etiopathogenic mechanisms, although no studies have been found to date that have investigated this. Therefore, the aim of the study was to evaluate the bone density, periodontal status and biochemistry variables to determinate if there is a relationship between both pathologies.</p><p><strong>Material and methods: </strong>A case-control study was carried out with 86 cases (NPHPT) and 87 controls. Bone density was evaluated through computed tomography, measured in Hounsfield units, in seven Regions of Interest. Periodontal status and biochemical variables, such as marker hormones of bone metabolism (25 OH vitamin D and PTH), were analyzed. A Student's t test, bivariate correlations were performed and the OR was calculated.</p><p><strong>Results: </strong>NPHPT patients are more susceptible to changes in the pattern of bone remodeling due to elevated serum levels of PTH and a decrease in 25OH vitamin D under conditions of normocalcemia. The 58.9% of cases group had periodontitis Stage IV, 27% Stage III, 9.45% Stage II and 8.1% with Stage I. Control group showed a 32% periodontitis Stage IV, 39% Stage III, 8.82% have Stage II and 16.2% Stage I.</p><p><strong>Conclusions: </strong>There was an association between NPHPT and periodontitis, with patients with NPHPT showing a 1.78 (OR) greater probability of suffering from periodontitis. Our biochemical results showed that the increase in PTH and the decrease in 25OH VIT-D were associated with loss of bone density and these patients presented advanced periodontitis.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e151-e159"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examination of parotid gland in diabetics with ultrasound elastography and microvascular imaging.","authors":"S Erdem, A Tosun","doi":"10.4317/medoral.26865","DOIUrl":"10.4317/medoral.26865","url":null,"abstract":"<p><strong>Background: </strong>Diabetes mellitus is a prevalent metabolic disorder that can result in the non-enflamatuar enlargement of the parotid gland. It is recognised as a condition that can impair microvascular perfusion.</p><p><strong>Material and methods: </strong>The parotid glands of 38 individuals with diabetes and 38 healthy controls were examined bilaterally using ultrasound to assess parameters of volume, stiffness and microvascularity.</p><p><strong>Results: </strong>A statistically significant increase in parotid gland volume and a statistically significant decrease in microvascularity were observed in diabetic patients. Furthermore, a statistically significant increase in parotid gland volume was noted in diabetic individuals who were using antidiabetic drugs in comparison to non-users. A significant negative correlation was identified between the duration of exposure to diabetes and microvascularity.</p><p><strong>Conclusions: </strong>Ultrasonographic imaging can be used to assess the dimensions and microvascularity of the parotid gland.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e117-e123"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral pathology in a population observed within an oral cancer screening developed in Portugal.","authors":"D Pereira, M Andrade, A Moreira, J Caramês, M Pojo, F Freitas","doi":"10.4317/medoral.26863","DOIUrl":"10.4317/medoral.26863","url":null,"abstract":"<p><strong>Background: </strong>Oral cancer is a global public health problem. Late diagnosis leads to treatment delays, which consequently result in a worse prognosis and a decrease in the 5-year survival rate. The purpose of this study is to evaluate the oral pathology in a population observed within an oral cancer screening developed in Portugal.</p><p><strong>Material and methods: </strong>Oral cancer opportunistic screening activities were conducted by the non-profit organization Liga Portuguesa Contra o Cancro ‑ Núcleo Regional do Sul (LPCC-NRS) and data collection occurred between March and December 2022. Participants completed an anonymous questionnaire to collect sociodemographic data and lifestyle habits, followed by a clinical examination of the oral cavity. All individuals classified with oral potentially malignant disorders (OPMD), or suspected lesions of malignant neoplasia were subsequently contacted between January and February 2023 and were questioned about undergoing a biopsy and its respective pathological examination result. Descriptive and analytical statistics were applied.</p><p><strong>Results: </strong>A total of 2674 participants with a mean age of 57 years were screened. Fordyce granules (16.30%) were the most common non-pathological condition, and hairy tongue (11.04%) was the most frequently observed benign lesion. Leukoplakia (43.58%) was the most common oral potentially malignant disorder. Additionally, histological confirmation was obtained for the presence of 4 oral squamous cell carcinomas (OSCC), representing 0.15% of all population screened.</p><p><strong>Conclusions: </strong>Although benign pathology is the most frequently found, oral potentially malignant disorders and suspected malignant lesions were identified in 6.3% of participants in these oral cancer screenings. In this regard, we conclude that the oral cancer screening actions developed by LPCC-NRS were effective in identifying positive cases of OPMDs and oral cancer, using an intraoral visual examination of the oral cavity.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e107-e116"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is the mandibular buccal shelf anatomy related to craniofacial morphology? A cross-sectional CBCT study.","authors":"M-D Campoy, S Chiquillo-Enguix, V García-Sanz, J-C Pérez-Varela, S Camañes-Gonzalvo, V Paredes-Gallardo","doi":"10.4317/medoral.26897","DOIUrl":"10.4317/medoral.26897","url":null,"abstract":"<p><strong>Background: </strong>The placement of Temporary Anchorage Devices (TADs) in the mandibular buccal shelf area is a common option for distalizing the lower arch. Therefore, the study of bone thickness and depth in this area is mandatory before planning TAD insertion. The aim of this study was to quantify the width and depth of the mandibular buccal shelf structure and examine its associations with sex, age, skeletal class and vertical pattern.</p><p><strong>Material and methods: </strong>A cross-sectional study was carried out on cone beam computed tomographies obtained from 91 patients. The bone thickness was evaluated in the mandibular buccal shelf area 5 and 8 mm apical to the cement-enamel junction (CEJ), and the bone depth was measured 4 mm buccal to the CEJ at the level of the distal root of the mandibular first molar and the mesial root of the mandibular second molar using the InVivoDental 6.0 software.</p><p><strong>Results: </strong>The depth and thickness of the bone increased in distal areas, and the thickness was greater at 8 mm. No differences were found between sex or skeletal class. Bone thickness decreased with age, and it was significantly lower in hyperdivergent patients.</p><p><strong>Conclusions: </strong>The thickness of the bone was higher in distal and deeper areas, and the depth was greater in distal areas. The hyperdivergent facial pattern and age were negatively associated with bone thickness.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":"30 1","pages":"e135-e140"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of a new mouthwash formulated with Chlorhexidine and Cymenol after a scaling and root planing treatment in grade I and II periodontal patients.","authors":"P Hermida-Cabrera, F Aguilera, F Vivancos-Cuadras, L Ferrá-Domingo, D Torres-Lagares, J Gutiérrez-Pérez, T Pereira-Riveros, T-V Serrera-Figallo, M Baus-Domínguez","doi":"10.4317/medoral.26818","DOIUrl":"10.4317/medoral.26818","url":null,"abstract":"<p><strong>Background: </strong>Periodontal disease (PD) is a chronic inflammatory disease of multifactorial origin that affects the supporting tissues of the tooth. According to WHO in 2022, severe periodontal disease will affect around 19% of the adult population worldwide. Its risk factors include the presence of periodontopathogenic bacteria in biofilm and the susceptibility of the host's immune system, among others. Preterm birth is defined as birth occurring before 37 weeks of gestational age. It also has a multifactorial origin and it's associated with risk factors such as intrauterine and extrauterine infections. There is a possibility that periodontal disease in pregnant women increases the risk of preterm birth through hematogenous pathways or the presence and intervention of inflammatory mediators.</p><p><strong>Material and methods: </strong>Through a systematic review of existing scientific articles from 2014 to 2024, five randomized clinical trials were selected, including a total of 1984 pregnant patients diagnosed with periodontal disease. Half of these patients received non-surgical treatment, while the other half did not, aiming to evaluate a possible association between periodontal disease and/or its treatment and the occurrence of preterm birth. The risk of bias was assessed using the Cochrane \"RoB 2\" tool, and finally, a meta-analysis was conducted to compare the results obtained in the selected studies.</p><p><strong>Results: </strong>Four articles showed a trend favoring non-surgical periodontal treatment as a preventive measure for preterm birth. These articles accounted for 92.2% of the total weight, while the remaining 7.85% corresponded to the single article that did not favor the treatment. However, none of the articles showed statistically significant results.</p><p><strong>Conclusions: </strong>There is no demonstrated association between periodontal disease in pregnant women and the incidence of preterm birth. On the other hand, there is a slightly favorable trend towards non-surgical periodontal treatment during pregnancy as a measure to reduce the incidence of preterm birth, but it's not statistically significant. To obtain a definitive answer, more randomized clinical trials following similar study and design parameters are needed.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":"e843-e849"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11584970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}