{"title":"Effects of ozone therapy on postoperative pain, swelling, and trismus caused by surgical extraction of unerupted lower third molars: a double-blinded split-mouth randomized controlled trial.","authors":"R-B Almeida, F-U Campos, J-C Ramacciato, D-C Peruzzo, G-V Fernandes, J-C Joly, M Sperandio","doi":"10.4317/medoral.26974","DOIUrl":"https://doi.org/10.4317/medoral.26974","url":null,"abstract":"<p><strong>Background: </strong>Third molar extraction surgery is a common procedure, but it results in pain, swelling, and trismus. Ozone therapy (Oz) has emerged as a viable option for pain control and as an option to limit bacterial growth, improving the wound healing. Then, this randomized controlled trial aimed to evaluate the effectiveness of adjunctive use of ozone therapy (OzT) in managing pain, swelling, and trismus after lower third molar removal.</p><p><strong>Material and methods: </strong>A split-mouth design was selected, enrolling 60 patients. There were 2 groups (Sham and OzT). The same surgeon performed all procedures. The pain was evaluated using the VAS scale and the number of paracetamol tablets taken. The quality of life was assessed using the OHIP-14 questionnaire. The data were statistically evaluated.</p><p><strong>Results: </strong>120 surgical procedures were performed on 60 participants (34 males [56%] and 26 females [44%]). Regarding the number of paracetamol tablets taken, the test group had a significantly lower consumption (p<0.002). In addition, the test group presented a significantly lower pain score on days 1, 3, and 5 postoperatively, with no difference between groups on the 7th day (p<0.0145). Both sides presented postoperative edema, which regressed from day 5 (no significant difference). A similar case scenario was observed for mouth opening. OzT impacted the patient's quality of life (OHIP-14, p<0.05), favoring ozone therapy.</p><p><strong>Conclusions: </strong>The results demonstrated that OzT is an effective adjunctive strategy for reducing postoperative pain following the extraction of lower third molar teeth.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating quality of life in third molar surgery: a scoping review of the postoperative symptom severity (PoSSe) scale.","authors":"E-F Maferano, E-L Filho, P-G Silva, A-F Granville-Garcia, R-T Firmino, M-D Perazzo, P-R Martins-Filho, F-W Costa","doi":"10.4317/medoral.26839","DOIUrl":"https://doi.org/10.4317/medoral.26839","url":null,"abstract":"<p><strong>Background: </strong>This scoping review evaluated the key dimensions of quality of life impacted by third molar surgery as assessed by the Postoperative Symptom Severity (PoSSe) scale, and their variations across diverse populations and clinical contexts.</p><p><strong>Material and methods: </strong>A comprehensive literature search was performed across multiple databases including MEDLINE, EMBASE, CINAHL, PsycINFO, The Cochrane Library, Livivo, LILACS, Web of Science, Scopus, Epistemonikos, and Google Scholar on April 30, 2024, with an update on July 31, 2024. We included analytical observational studies and randomized clinical trials that utilized the PoSSe scale to assess quality of life. There were no restrictions based on language, location, or publication period. Data from eligible studies were extracted and analyzed descriptively.</p><p><strong>Results: </strong>The search identified 3,438 records, with 31 studies ultimately included. These studies employed the PoSSe scale in various methodological designs to primarily assess quality of life following lower third molar removal. The dimensions most affected were feeding, appearance, and pain, which showed significant correlations with edema, trismus, and analgesic use. Additional influencing factors included gender, tobacco use, surgeon skill level, Pell and Gregory classification, and preemptive analgesia.</p><p><strong>Conclusions: </strong>This review has demonstrated the PoSSe scale's effectiveness in evaluating the multifaceted impacts of third molar surgery on patient quality of life, sensitive to differences in surgical techniques, surgeon experience, and patient-specific factors. Future research should explore longitudinal assessments with the PoSSe scale to optimize surgical practices and improve long-term patient outcomes.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between prediabetes and periodontitis: a meta-analysis of observational studies with multivariate analysis.","authors":"Y Zhou, F Sun, Q Zhu","doi":"10.4317/medoral.26961","DOIUrl":"https://doi.org/10.4317/medoral.26961","url":null,"abstract":"<p><strong>Background: </strong>Growing evidence suggests that prediabetes may increase the risk of periodontitis, though the extent of this association remains unclear. To provide a clearer understanding, this meta-analysis focused on observational studies that utilized multivariate analyses to adjust for key confounding factors.</p><p><strong>Material and methods: </strong>A comprehensive search of PubMed, Embase, and Web of Science was conducted to identify observational studies assessing the relationship between prediabetes and periodontitis. Only studies that utilized multivariate analyses were included to minimize confounding bias. The quality of the studies was evaluated with the Newcastle-Ottawa Scale (NOS). Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using a random-effects model, with heterogeneity assessed by the I² statistic.</p><p><strong>Results: </strong>Ten observational studies with 38,727 participants were included. Overall, individuals with prediabetes had a significantly higher risk of periodontitis compared to normoglycemic individuals (OR: 1.27, 95% CI: 1.09 to 1.48, p < 0.001) with moderate heterogeneity (I² = 53%). Subgroup analyses revealed a stronger association in studies where the proportion of men was < 45% compared to those ≥ 45% (OR: 1.75 vs. 1.15, p for subgroup difference = 0.01). Studies with lower quality (NOS score = 7) showed a stronger association compared to higher-quality studies (NOS score = 8 or 9, p for subgroup difference = 0.003).</p><p><strong>Conclusion: </strong>This meta-analysis found that prediabetes may be independently associated with an increased risk of periodontitis. Further research is needed to explore the mechanisms underlying this association and potential sex-specific effects.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Minimally invasive treatment of benign oral vascular lesions: A retrospective study.","authors":"H-C Silva, A-C Teles, G-F Rocha, E-M Silveira, D-W Douglas-de-Oliveira, A-T Mesquita","doi":"10.4317/medoral.26809","DOIUrl":"https://doi.org/10.4317/medoral.26809","url":null,"abstract":"<p><strong>Background: </strong>The ethanolamine oleate (EO) in different concentrations has been used in sclerotherapy of oral benign vascular lesions (OBVLs). The aim of the present study was to define demographic and clinical characteristics of patients with OBVLs treated with 5% EO.</p><p><strong>Material and methods: </strong>A retrospective study was conducted of cases treated by sclerotherapy from 1992 to 2022, and medical records of 52 patients with OBVLs were analysed. Thus, 44 cases with complete data were selected and described. Categorical data were analyzed using the chi-square test, with the significance level set at 5% (p < 0.05).</p><p><strong>Results: </strong>Mean age was 52.89 years (range seven to 82 years). The female sex was predominant (77%) and brown was the most common skin color (54%). Most lesions occurred on the lower lip (65.9%), tongue (11.4%), buccal mucosa (9.1%), upper lip (6.8%) ande palate (25%.3%). Approximately 73% of the lesions were ≤ 1 cm, > 1 ≤ 2 cm (18.2%,) and > 2 cm (9.1%). Complete regression of the lesions occurred in 97.7% of the cases, with no case of recurrence and no need for complementary surgery. All patients were satisfied with the treatment.</p><p><strong>Conclusions: </strong>Sclerotherapy with 5% EO is a safe and effective method for the treatment of OBVLs.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oral side effects of fluoxetine in patients with depressive disorder: A systematic review.","authors":"M-G Sarrión Pérez, Y Jiménez, L Bagan, J Bagan","doi":"10.4317/medoral.26947","DOIUrl":"https://doi.org/10.4317/medoral.26947","url":null,"abstract":"<p><strong>Background: </strong>Selective serotonin reuptake inhibitors are currently the preferred drugs for treating depression, a condition that has become more prevalent in recent years. Fluoxetine is one of the most widely used, but, like other antidepressants, it can cause several systemic and oral adverse effects. This systematic review aimed to analyze the frequency of oral adverse effects of fluoxetine in comparison to other antidepressants.</p><p><strong>Material and methods: </strong>For this purpose, a search was conducted in the Medline, Scopus, Cochrane, and Web of Science databases, which included randomized clinical trials and observational studies.</p><p><strong>Results: </strong>A total of 333 articles were collected. After eliminating duplicates, articles that did not meet the inclusion criteria were discarded, and 31 studies were ultimately selected.</p><p><strong>Conclusions: </strong>Dry mouth was the most prevalent oral adverse effect associated with fluoxetine, with a frequency rate ranging from 2.71% to 52.17%. However, it was less frequent compared to other antidepressants. It is unclear whether this sensation is accompanied by decreased salivary flow, as the studies did not perform objective determinations. Regarding dysgeusia, its frequency could not be analyzed since only two articles collected data on it. The selected articles also mention other adverse effects, such as nausea or vomiting. However, none of them evaluated the potential oral manifestations resulting from these effects.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intelligent biofilm detection with ensemble of deep learning networks.","authors":"B-P Sobrinho, B-P Silva, K-M Andrade, B-P Sobrinho, D-A Ribeiro, J-N Santos, L-R Oliveira, P-R Cury","doi":"10.4317/medoral.26937","DOIUrl":"https://doi.org/10.4317/medoral.26937","url":null,"abstract":"<p><strong>Background: </strong>Dental biofilm is traditionally identified visually, which can be challenging and time-consuming due to its color similarity with the tooth. The aim of this study was to evaluate the performance of U-Net neural networks for the automatic detection of dental biofilm without disclosing agents on intraoral photographs of deciduous and permanent teeth using an ensemble strategy.</p><p><strong>Material and methods: </strong>This retrospective exploratory study was conducted on two datasets of intraoral images obtained from deciduous and permanent dentitions. The first dataset was used to validate dental biofilm annotations by an expert with disclosing agents. The second dataset, without disclosing agents, was employed to train and evaluate the U-Net neural network in the identification of dental biofilms using an ensemble strategy.</p><p><strong>Results: </strong>The performance of the ensemble method was assessed using a cross-validation procedure, with six groups dedicated to training, one group for validation, and one group exclusively taken as a test set for the final evaluation of the ensemble. The performance of the neural network was evaluated using accuracy, F1 score, sensitivity, and specificity. The U-Net neural network achieved an accuracy of 93.1%, sensitivity of 65.1%, specificity of 95.9%, and an F1 score of 63.0%.</p><p><strong>Conclusions: </strong>The U-Net neural network using the ensemble strategy was able to automatically identify visually detectable dental biofilms on intraoral photographs. The application of this new knowledge will soon be available in clinical practice.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E-O Sousa, N-A Mirsky, M Parra, V-V Nayak, B-L Silva, E-A Bonfante, N Tovar, P-G Coelho, L Witek
{"title":"Socket preservation utilizing polymeric bioresorbable membranes: a preclinical model.","authors":"E-O Sousa, N-A Mirsky, M Parra, V-V Nayak, B-L Silva, E-A Bonfante, N Tovar, P-G Coelho, L Witek","doi":"10.4317/medoral.26938","DOIUrl":"https://doi.org/10.4317/medoral.26938","url":null,"abstract":"<p><strong>Background: </strong>The preservation of the alveolar ridge following tooth extraction is crucial to prevent atrophy and maintain structural integrity, facilitating future dental rehabilitations. This study compared the use of two different polymeric, resorbable membranes: polylactic acid (PLA), and 5% polylactic acid + 95% polycaprolactone (PLA/PCL), relative to unassisted socket healing (negative control).</p><p><strong>Material and methods: </strong>A preclinical model involving healthy, skeletally mature beagles (n=7) were used in this study. Surface topography and thermal degradation of the membranes were assessed, followed by in vivo evaluation of socket preservation in extracted maxillary premolars. Histomorphometric analysis was employed to measure bone formation and total socket area. Data was analyzed through linear mixed models with fixed factor of treatment following a post-hoc comparison by the Tukey test. Ranked data of residual membrane presence and inflammatory infiltrate were analyzed through Kruskal-Wallis non-parametric test. All analyses were conducted with statistical significance set at p-value ≤ 0.05.</p><p><strong>Results: </strong>Surface topography depicted a distinctive fibrous network structure for PLA membrane relative to PLA/PCL which exhibited a more porous architecture. Thermal degradation behavior/profile, observed through TGA and DSC, for both membranes was similar. Histomorphometric analysis of bone formation within the induced socket yielded 36.1 ±7.7%, 35.6 ±7.2% and 32.8 ±7.7% for control, PLA and PLA/PCL groups, respectively, with no statistically significant differences between groups (p = 0.796). Analysis of total socket area (mean ± 95% confidence intervals) yielded significantly higher values for experimental groups, PLA (8.95 ± 1.7 mm2) and PLA/PCL (8.8 ± 1.76 mm2), relative to control (6.7 ± 1.8 mm2) (p = 0.041). Residual membrane, along with mild inflammatory infiltrate was observed after the healing period irrespective of membrane type utilized.</p><p><strong>Conclusions: </strong>Guided bone regeneration (GBR) with PLA and PLA/PCL membranes did not yield higher bone formation within the socket relative to the control group. However, an improvement in the preservation of the socket's architecture was observed.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Boronat-López, J-C Bernabeu-Mira, M Peñarrocha-Diago, M Peñarrocha-Diago, D Peñarrocha-Oltra
{"title":"Dimensional changes in buccal cortical bone and lesion volume in teeth with persistent chronic periapical disease subjected to periapical surgery: a cone beam computed tomography study at one year of follow-up.","authors":"A Boronat-López, J-C Bernabeu-Mira, M Peñarrocha-Diago, M Peñarrocha-Diago, D Peñarrocha-Oltra","doi":"10.4317/medoral.27006","DOIUrl":"https://doi.org/10.4317/medoral.27006","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate changes in buccal cortical bone and lesion volume in teeth with persistent periapical disease one year after periapical surgery using cone-beam computed tomography (CBCT).</p><p><strong>Material and methods: </strong>A prospective study was conducted involving patients with persistent periapical disease undergoing periapical surgery, with one year of follow-up. Data collected included patient age, gender, teeth involved, and the number of roots/lesions. CBCT measurements were taken preoperatively and one year post-surgery, including the distance from the cementoenamel junction to the buccal bone crest (CEJ-BBC), marginal bone loss, buccal cortical height, presence of fenestration, apical depth, cortical bone width at 1, 3, and 5 mm from the buccal bone crest, and lesion volume in mm³. Success was assessed using the \"Modified Penn 3D criteria.\"</p><p><strong>Results: </strong>The study included 92 patients with 111 roots exhibiting persistent chronic periapical lesions. Statistically significant changes were observed in all buccal cortical bone parameters one year after surgery. The CEJ-BBC distance increased, indicating a marginal bone loss of 0.23 mm. Notably, the height from the buccal cortical bone crest to the lesion, apical depth, buccal bone thickness, the number of fenestrations, and lesion volume decreased (91.1%). Buccal cortical bone thickness was a predictor of volume reduction, showing a significant relationship at T1 between greater thickness and smaller volume variation. Patient age and gender did not significantly influence these changes. Fenestrations and larger lesion volumes correlated with reduced healing probabilities. The overall success rate was 88%, with tooth position and root involvement impacting healing outcomes.</p><p><strong>Conclusions: </strong>One year post-surgery, buccal cortical bone showed no clinically relevant changes, while lesion volume decreased by 91.1%, more significantly in anterior teeth. Greater buccal cortical bone width was associated with smaller volume reduction. A larger lesion volume and presence of fenestrations adversely affected healing rates.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Outcomes of removing the fracture fragments in the treatment of intracapsular condylar fractures in children.","authors":"J Dai, C Gong, D Diarra, Z Li","doi":"10.4317/medoral.27079","DOIUrl":"https://doi.org/10.4317/medoral.27079","url":null,"abstract":"<p><strong>Background: </strong>Treatment methods for mandibular condylar fractures in children can be broadly divided into closed treatment and open treatment (open reduction and internal fixation). The aim of the study is to evaluate the feasibility of removing the fracture fragments when treating intracapsular condylar fractures in children.</p><p><strong>Material and methods: </strong>A retrospective study was performed in patients aged ≤12 years with intracapsular condylar fractures treated with removal of the fracture fragments from June 2010 through June 2018. The preoperative and postoperative data of physical complaints, facial asymmetry, maximal interincisal distance, occlusal relationship and radiographic examinations were extracted from the patients' records. The collected preoperative and postoperative data were analysed.</p><p><strong>Results: </strong>Thirteen intracapsular condylar fractures in nine cases were subjected to fracture fragments removal. In these patients, clinical and radiographic results at different follow-up periods displayed normal occlusion and satisfactory bone healing. New condyles were found to be regenerated, in the cases with follow-up period longer than 3 months.</p><p><strong>Conclusions: </strong>Removal of fracture fragments proves to be effective in delivering satisfactory clinical results and permitting ongoing condyle remodelling and regeneration.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z Tastan Eroglu, O Babayigit, F Ucan Yarkac, K Yildiz, D Ozkan Sen
{"title":"Evaluating diode laser and conventional scalpel techniques in maxillary labial frenectomy for patient perception, tissue healing, and clinical efficacy: six-month results of a randomized controlled study.","authors":"Z Tastan Eroglu, O Babayigit, F Ucan Yarkac, K Yildiz, D Ozkan Sen","doi":"10.4317/medoral.26931","DOIUrl":"https://doi.org/10.4317/medoral.26931","url":null,"abstract":"<p><strong>Background: </strong>This study aims to compare scalpel and diode laser techniques regarding patients' perceptions, tissue healing, diastema, and periodontal clinical parameters in the treatment of abnormal labial frenum.</p><p><strong>Material and methods: </strong>This prospective, randomized, controlled trial evaluated 43 patients (aged 18-55) requiring labial frenectomy, randomized to scalpel or diode laser therapy. Plaque index (PI) and gingival index (GI) were measured at baseline, 4 weeks, and 6 months post-surgery. Keratinized gingiva width (KGW) of maxillary central incisors and diastemas were measured at baseline and 6 months post-surgery. Postoperative pain was evaluated on days 1, 7, 14, 21, and 28 using a visual analog scale. Wound healing was assessed at 7 days and 4 weeks postoperatively, scored based on the degree of epithelialization and the presence of ulceration or necrosis.</p><p><strong>Results: </strong>At 6 months, both groups showed a significant reduction in PI, GI, and diastema (P<0.05). KGW increased in both groups, with a significant increase in the laser group (P<0.05), though baseline and 6-month KGW values were not significantly different between groups: baseline values were 5.30 ± 1.396 for the scalpel group and 5.05 ± 1.276 for the laser group, and 6-month values were 5.65 ± 1.152 for the scalpel group and 5.50 ± 1.147 for the laser group (P<0.05). The diode laser group had significantly lower pain scores than scalpel group on days 1, 3, and 7 (P<0.05). however, from day 14 onward, there was no statistically significant difference in pain scores between groups (P<0.05). Tissue healing was significantly faster on day 7 in the scalpel group (P<0.05).</p><p><strong>Conclusions: </strong>Frenectomy with diode laser effectively reduces pain, although it may delay wound healing. Laser therapy serves as a feasible alternative to the scalpel method. However, further research is necessary to fully assess its benefits and limitations in soft tissue procedures.</p>","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}