Journal of Periodontal and Implant Science最新文献

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Association between dietary quality and the prevalence of periodontitis in older Korean adults aged 60 or over. 饮食质量与60岁以上韩国老年人牙周炎患病率之间的关系。
IF 2.2 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2024-08-01 Epub Date: 2023-11-13 DOI: 10.5051/jpis.2301840092
Eurim C Hwang, Horim A Hwang, Seung-Yun Shin, Joungmok Kim, Jeong Hee Kim
{"title":"Association between dietary quality and the prevalence of periodontitis in older Korean adults aged 60 or over.","authors":"Eurim C Hwang, Horim A Hwang, Seung-Yun Shin, Joungmok Kim, Jeong Hee Kim","doi":"10.5051/jpis.2301840092","DOIUrl":"10.5051/jpis.2301840092","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the association between dietary quality and the prevalence of periodontitis in older Korean adults (≥60 years of age) using data from the seventh Korea National Health and Nutrition Examination Survey (KNHANES VII, 2016-2018).</p><p><strong>Methods: </strong>Among the 16,489 KNHANES participants from 2016-2018, those aged ≥60 years were selected as the eligible population. After applying our exclusion criteria, 3,527 participants were included in the final study population. Periodontal status was measured using the Community Periodontal Index (CPI). To determine the association between dietary quality and the prevalence of periodontitis, analysis of variance, the chi-square (χ²) test, and logistic regression analysis were performed.</p><p><strong>Results: </strong>The population was divided into quartile groups and stratified by sex. The percentage of men and women with periodontitis was 54.34% and 42.74%, respectively. The quartile with higher Korean Healthy Eating Index scores had a lower percentage of people with periodontitis in both sexes. For men, only vegetable intake showed a significant difference between sub-groups with or without periodontitis, whereas, for women, the intake of fruits, milk, sweets, carbohydrates, and fats showed significant differences. There was a strong positive association between vegetable intake and periodontitis in men in the 3 models used in this study; model 3 had an adjusted odds ratio (aOR) of 1.367 (95% confidence interval [CI], 1.091-1.712). In women, a strong positive association with periodontitis was shown for sweets in all 3 models, with an aOR of 1.477 in model 3 (95% CI, 1.125-1.939).</p><p><strong>Conclusions: </strong>Dietary quality was inversely associated with the prevalence of periodontitis in Korean adults aged ≥60 years. Further comprehensive studies are needed to help establish nutrition and health policies for older adults in Korea.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11377895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138446600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of adjacent periodontitis on osseointegrated dental implants. 邻近牙周炎对种植体的影响。
IF 2.2 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2024-08-01 Epub Date: 2023-11-06 DOI: 10.5051/jpis.2302400120
Keun-Soo Ryoo, Kyoung-Hwa Kim, Young-Dan Cho, Yang-Jo Seol, Young Ku
{"title":"Effects of adjacent periodontitis on osseointegrated dental implants.","authors":"Keun-Soo Ryoo, Kyoung-Hwa Kim, Young-Dan Cho, Yang-Jo Seol, Young Ku","doi":"10.5051/jpis.2302400120","DOIUrl":"10.5051/jpis.2302400120","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate whether new-onset periodontitis or apical periodontitis in the adjacent teeth affects osseointegrated dental implants in a beagle dog model.</p><p><strong>Methods: </strong>One control group and 2 experimental groups (periodontitis and apical periodontitis groups) were defined based on the presence of experimental periodontitis or apical periodontitis, with 1 beagle dog randomly assigned to each group. The mandibular second and fourth premolars on both sides of the 3 beagles were extracted. Eight weeks after extraction, 4 bone-level implant fixtures, 2 on both sides of each mandible, were placed in each beagle. Six weeks after implant surgery, healing abutments were connected. After sufficient osseointegration, plaque control was performed in the control group, while periodontitis and apical periodontitis were induced in the experimental groups. The beagles were euthanized for histological analyses 20 weeks after induction of experimental periodontitis. Statistical analyses were performed using the Kruskal-Wallis test with the Bonferroni correction to compare the 3 groups.</p><p><strong>Results: </strong>The implants in the control and apical periodontitis groups were well-maintained, while those in the periodontitis group showed clinical signs of inflammation with bone resorption. The bone-to-implant contact (BIC) and bone area values in the periodontitis group were lower than those in the other groups. The distance between the implant shoulder and the first BIC was significantly greater in the periodontitis group than in the control group (<i>P</i><0.05).</p><p><strong>Conclusions: </strong>The presence of periodontitis in adjacent teeth can pose a risk to dental implants, potentially resulting in peri-implantitis. However, this was not observed for apical periodontitis. Within the limitations of this study, periodontal care is necessary to reduce the impact of periodontitis in adjacent teeth on osseointegrated implants.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11377894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138446602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical evaluation of root coverage in Miller class III/RT2 labial gingival recession treated with interdisciplinary periodontal-orthodontic therapy: a randomized controlled clinical trial. 采用跨学科牙周-正畸疗法治疗米勒 III/RT2 级唇侧牙龈退缩的牙根覆盖临床评估:随机对照临床试验。
IF 2.2 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2024-08-01 Epub Date: 2023-11-20 DOI: 10.5051/jpis.2204100205
Sakshi Malhotra, Shikha Tewari, Rekha Sharma, Rajinder Kumar Sharma, Nishi Tanwar, Ritika Arora
{"title":"Clinical evaluation of root coverage in Miller class III/RT2 labial gingival recession treated with interdisciplinary periodontal-orthodontic therapy: a randomized controlled clinical trial.","authors":"Sakshi Malhotra, Shikha Tewari, Rekha Sharma, Rajinder Kumar Sharma, Nishi Tanwar, Ritika Arora","doi":"10.5051/jpis.2204100205","DOIUrl":"10.5051/jpis.2204100205","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of current study was to evaluate percentage root coverage (RC%) in isolated Miller class III/RT2 labial gingival recession (GR) associated with malaligned mandibular anteriors, using interdisciplinary periodontal-orthodontic treatment as compared to mucogingival surgery alone.</p><p><strong>Methods: </strong>Thirty-six systemically healthy patients having isolated Miller class III/RT2 GR with respect to malaligned mandibular anteriors, were randomly divided into test group: mucogingival surgery using subepithelial connective tissue graft followed by orthodontic treatment and control group: mucogingival surgery alone. Primary clinical parameters included (RC%), recession depth, keratinized tissue width, mid-labial clinical attachment level, interdental clinical attachment level (iCAL), periodontal phenotype (PP), gingival thickness (GT), root coverage esthetics score (RES) and hypersensitivity. Total duration of follow up was 12 months.</p><p><strong>Results: </strong>Mean RC% was significantly more achieved in test group (66.67%±40.82%) in comparison to control group (39.93%±31.41%) at the end of study (<i>P</i>=0.049). Further, complete root coverage was attained in 5/8 cases of test group versus 1/2 cases of control group after 3/12 months respectively. RES and hypersensitivity, showed statistically significant improvement after complete follow up period in both the groups. An ideal RES score of 10 was achieved in 4/7 cases of test group while in 1/2 cases of control group after 3/12 months respectively. Correlation analysis revealed significant negative correlation between RC% and iCAL. Correlation of RC% with GT and PP was non-significant.</p><p><strong>Conclusions: </strong>Interdisciplinary periodontal-orthodontic approach may be more beneficial in terms of achieving improved RC%, esthetic and resolution of hypersensitivity in the management of Miller class III/RT2 GR in malaligned mandibular anteriors.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov Identifier: NCT04255914.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11377891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139643197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of early wound healing using modified papilla preservation technique between enamel matrix derivative and recombinant human fibroblast growth factor. 改良乳头保存技术在牙釉质基质衍生物和重组人成纤维细胞生长因子早期创面愈合中的比较。
IF 2.2 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2024-08-01 Epub Date: 2023-11-13 DOI: 10.5051/jpis.2303080154
Yohei Nakayama, Shinichi Tabe, Kazuma Igarashi, Satoshi Moriya, Tsuyoshi Katsumata, Ryo Kobayashi, Shuta Nakagawa, Tomoko Nishino, Namiko Fukuoka, Kota Hosono, Mai Yamasaki, Yosuke Yamazaki, Moe Ogihara-Takeda, Shoichi Ito, Yumi Saito, Arisa Yamaguchi, Yuto Tsuruya, Mizuho Yamazaki-Takai, Shoichi Yoshino, Hideki Takai, Yorimasa Ogata
{"title":"Comparison of early wound healing using modified papilla preservation technique between enamel matrix derivative and recombinant human fibroblast growth factor.","authors":"Yohei Nakayama, Shinichi Tabe, Kazuma Igarashi, Satoshi Moriya, Tsuyoshi Katsumata, Ryo Kobayashi, Shuta Nakagawa, Tomoko Nishino, Namiko Fukuoka, Kota Hosono, Mai Yamasaki, Yosuke Yamazaki, Moe Ogihara-Takeda, Shoichi Ito, Yumi Saito, Arisa Yamaguchi, Yuto Tsuruya, Mizuho Yamazaki-Takai, Shoichi Yoshino, Hideki Takai, Yorimasa Ogata","doi":"10.5051/jpis.2303080154","DOIUrl":"10.5051/jpis.2303080154","url":null,"abstract":"<p><strong>Purpose: </strong>Enamel matrix derivative (EMD) has demonstrated beneficial effects on wound healing following surgery. However, the effects of recombinant human fibroblast growth factor 2 (rhFGF-2) in periodontal regeneration therapy have not been extensively studied. This retrospective study was conducted to compare the wound healing outcomes of the modified papilla preservation technique (mPPT) between EMD and rhFGF-2 therapies.</p><p><strong>Methods: </strong>A total of 79 sites were evaluated for early wound healing using the modified early wound healing index (mEHI), which included 6 items: incision, fibrin clotting, step, redness, swelling, and dehiscence. A numeric analog scale, along with postoperative images of the 6 mEHI items, was established and used for the evaluations. The inter-rater reliability of the mEHI was assessed via intraclass correlation coefficients (ICCs). After adjusting for factors influencing the mPPT, the differences in mEHI scores between the EMD and rhFGF-2 groups were statistically analyzed. Additionally, radiographic bone fill (RBF) was evaluated 6 months after surgery.</p><p><strong>Results: </strong>The ICC of the mEHI was 0.575. The mEHI, redness score, and dehiscence scores were significantly higher in the rhFGF-2 group (n=33) than in the EMD group (n=46). Similar results were observed in the subgroup of patients aged 50 years or older, but not in those younger than 50 years. In the subgroup with non-contained bone defects, related results were noted, but not in the subgroup with contained bone defects. However, early wound healing did not correlate with RBF at 6 months after surgery.</p><p><strong>Conclusions: </strong>Within the limitations of this study, the findings suggest that early wound healing following the use of mPPT with rhFGF-2 is somewhat superior to that observed after mPPT with EMD. However, mEHI should be improved for use as a predictive tool for early wound healing and to reflect clinical outcomes after surgery.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11377897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138446601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytotherapy in periodontics as an effective and sustainable supplemental treatment: a narrative review. 植物疗法在牙周病学中作为一种有效且可持续的辅助治疗方法:综述。
IF 2.2 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2024-08-01 Epub Date: 2023-12-11 DOI: 10.5051/jpis.2301420071
Abeer Saad Gawish, Mohammed Sherif ElMofty, Safa Jambi, Doaa Felemban, Yassmeen SalahEldin Ragheb, Shadia Abdelhameed Elsayed
{"title":"Phytotherapy in periodontics as an effective and sustainable supplemental treatment: a narrative review.","authors":"Abeer Saad Gawish, Mohammed Sherif ElMofty, Safa Jambi, Doaa Felemban, Yassmeen SalahEldin Ragheb, Shadia Abdelhameed Elsayed","doi":"10.5051/jpis.2301420071","DOIUrl":"10.5051/jpis.2301420071","url":null,"abstract":"<p><strong>Purpose: </strong>Periodontal disease is a chronic condition caused by microbial infection and mediated by the host's immune response. Phytotherapy is a therapeutic approach that utilizes a renewable resource capable of supplying less expensive medicines for the world's growing population. This review aimed to present clinical evidence on the use of complementary medicinal herbs in the treatment of periodontal diseases.</p><p><strong>Methods: </strong>Different databases were searched using the terms \"herbal\" and \"periodontitis.\" All included studies were examined with a focus on herbal indications, type, and prescription length. Dentists' therapeutic and prophylactic herbal prescribing habits were also assessed.</p><p><strong>Results: </strong>Various herbs such as turmeric, neem, aloe-vera, pomegranate, catechu, tulsi, cloves, lemon grass, green tea, tea tree oil, peppermint, garlic, pineapple, oak bark, babul, bakul, sage, coriander, moringa, amla, guava, and grape seed extract have been used in the treatment of periodontitis. These herbs have been reported to exhibit a range of therapeutic effects, including anti-inflammatory, antiplaque, antihalitosis, antiresorptive, antioxidant, antibacterial, antifungal, antiviral, and antimicrobial properties. These components can be utilized in various forms such as mouth rinse, gel, oil, toothpaste, aqueous extract, mouthwash, or tooth powder.</p><p><strong>Conclusions: </strong>Several readily available herbal formulations are now available on the market and have been shown to be effective as supplemental periodontal phytotherapy. However, these should be used under the supervision of a dental professional to ensure optimal benefits and effectiveness. Therefore, it is necessary to improve the understanding of suggested herbal prescription practices among dental professionals.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11377892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139643198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is drug use associated with the presence of periodontitis and oral lesions? A meta-analysis. 药物使用是否与牙周炎和口腔病变有关?一个荟萃分析。
IF 2.2 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2024-08-01 Epub Date: 2023-11-10 DOI: 10.5051/jpis.2302920146
Michele Natara Portilio, Mayara Colpo Prado, Lilian Rigo
{"title":"Is drug use associated with the presence of periodontitis and oral lesions? A meta-analysis.","authors":"Michele Natara Portilio, Mayara Colpo Prado, Lilian Rigo","doi":"10.5051/jpis.2302920146","DOIUrl":"10.5051/jpis.2302920146","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review investigated whether drug use is associated with the presence of oral lesions and periodontitis.</p><p><strong>Methods: </strong>A search was performed for studies that analyzed the presence of periodontitis and/or oral lesions in users of crack, cocaine, and/or marijuana in the PubMed, Scopus, and Web of Science databases. Observational studies in English, Spanish, or Portuguese, without limitation of year, age, and sex, were included. Studies that did not evaluate periodontitis and oral lesions according to the eligibility criteria were excluded. Two authors independently performed study selection and data extraction using a standardized form. The risk of bias of studies included in the meta-analysis was assessed using the Joanna Briggs Institute Critical Appraisal Checklist. The meta-analysis included studies that investigated the association of drug use with the outcome.</p><p><strong>Results: </strong>The initial search resulted in 9,279 articles, from which 16 studies with 15,434 participants were included in the review and 8 studies were included in the meta-analysis. Most studies that evaluated periodontitis in drug users and non-users found a positive association in users. Most studies that analyzed oral lesions reported a higher prevalence, association, or risk of oral lesions in drug users than in non-users. A critical evaluation identified a need to improve the control and reporting of confounding factors in studies on this topic. An association was found between periodontitis and the use of crack, cocaine, and/or marijuana (odds ratio [OR], 1.84; 95% confidence interval [CI], 1.04-3.27; <i>P</i>=0.04) and between oral lesions and the use of these drugs (OR, 2.13; 95% CI, 1.58-2.86; <i>P</i><0.001).</p><p><strong>Conclusions: </strong>Drug users are more likely to develop oral lesions and periodontitis than non-users. However, the results should be interpreted with caution, considering the heterogeneity and quality of the studies included in the analysis.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11377893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138446661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current advances in artificial intelligence in radiographic interpretation and reporting. 人工智能在放射影像判读和报告方面的最新进展。
IF 2.2 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2024-08-01 DOI: 10.5051/jpis.245404edi01
Hak-Sun Kim, Gyu-Tae Kim
{"title":"Current advances in artificial intelligence in radiographic interpretation and reporting.","authors":"Hak-Sun Kim, Gyu-Tae Kim","doi":"10.5051/jpis.245404edi01","DOIUrl":"10.5051/jpis.245404edi01","url":null,"abstract":"","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11377896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of cannabinoid receptor activation on Porphyromonas gingivalis lipopolysaccharide stimulation in human periodontal ligament stem cells in vitro. 大麻素受体激活对牙龈卟啉菌脂多糖体外刺激人类牙周韧带干细胞的影响。
IF 2.2 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2024-07-15 DOI: 10.5051/jpis.2303680184
Tim Leypold, Alix Herbsthofer, Rogerio B Craveiro, Michael Wolf, Justus P Beier, Tim Ruhl
{"title":"Effects of cannabinoid receptor activation on <i>Porphyromonas gingivalis</i> lipopolysaccharide stimulation in human periodontal ligament stem cells <i>in vitro</i>.","authors":"Tim Leypold, Alix Herbsthofer, Rogerio B Craveiro, Michael Wolf, Justus P Beier, Tim Ruhl","doi":"10.5051/jpis.2303680184","DOIUrl":"https://doi.org/10.5051/jpis.2303680184","url":null,"abstract":"<p><strong>Purpose: </strong>Periodontitis is an inflammatory disease that results in the loss of periodontal tissue. The endocannabinoid system has anti-inflammatory properties and displays considerable potential for tissue regeneration. In this study, we aimed to explore whether the activation of this system can alleviate or reverse the inflammatory phenotype of human periodontal ligament stem cells (hPDLSCs) induced by exposure to the inflammagen lipopolysaccharide (LPS).</p><p><strong>Methods: </strong>We investigated the effects of activating specific cannabinoid receptors (CB1 and CB2) on the inflammatory phenotype of LPS-stimulated hPDLSCs. The exogenous ligands WIN55,212-2 and JWH-133 were employed to target the cannabinoid receptors. We conducted a thorough assessment of cell proliferation, metabolic activity, and adipogenic, osteogenic, and chondrogenic differentiation potential. Additionally, we measured cytokine release using enzyme-linked immunosorbent assays.</p><p><strong>Results: </strong>Exposure to <i>Porphyromonas gingivalis</i> lipopolysaccharide (Pg-LPS) caused an increase in cell proliferation while decreasing metabolic activity. While this exposure did not influence adipogenic or chondrogenic differentiation, it did result in reduced osteogenesis. Additionally, LPS induced the release of interleukin (IL)-6, IL-8, and monocyte chemoattractant protein 1. Immunolabeling revealed the presence of CB1 and CB2 on the cellular membrane, with these receptors playing distinct roles in hPDLSCs. The CB1 agonist WIN55,212-2 was found to increase metabolic activity and promote adipogenic differentiation, whereas the CB2 agonist JWH-133 promoted cell proliferation and osteogenic differentiation. When hPDLSCs were co-exposed to Pg-LPS and CB ligands, JWH-133 slightly ameliorated the inhibition of osteogenic differentiation and suppressed the release of inflammatory cytokines.</p><p><strong>Conclusions: </strong>This study clarifies the effects of specific CB receptor activation on hPDLCs and the inflammatory phenotype. Stimulation of the endocannabinoid system through the manipulation of endogenous or the application of exogenous cannabinoids <i>in vivo</i> may represent a potent therapeutic option for combating periodontal inflammatory disorders.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of variations in the nasopalatine canal on CBCT: considerations from an anatomical point of view. 通过 CBCT 评估鼻腭管的变化:从解剖学角度考虑。
IF 2.2 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2024-07-12 DOI: 10.5051/jpis.2401300065
Utkarsh Yadav, Nandita Shenoy, Junaid Ahmed, Nanditha Sujir, Archana M, Aarti Gupta
{"title":"Assessment of variations in the nasopalatine canal on CBCT: considerations from an anatomical point of view.","authors":"Utkarsh Yadav, Nandita Shenoy, Junaid Ahmed, Nanditha Sujir, Archana M, Aarti Gupta","doi":"10.5051/jpis.2401300065","DOIUrl":"https://doi.org/10.5051/jpis.2401300065","url":null,"abstract":"<p><strong>Purpose: </strong>The nasopalatine canal (NPC) is one of the most significant anatomical markers in the anterior maxillary region. Its location is quite important, especially for implant placement. Therefore, the purpose of this study was to use cone-beam computed tomography (CBCT) to evaluate the morphology, size, and anatomic variations of the NPC.</p><p><strong>Methods: </strong>A total of 150 individual CBCT images were assessed in various sections to evaluate the dimensions, morphology, and extent of the NPC. Reformatted sagittal images were chosen to classify the shape and course of the canal. The Student's <i>t</i>-test, the χ² test, and Pearson correlation coefficients were used.</p><p><strong>Results: </strong>The NPC was longer in males than in females, and the mediolateral diameter of the canal was greater in older adults. In sagittal sections, the canal predominantly exhibits a cylindrical shape, while a spindle shape is the least common. In coronal sections, a single shape is most frequently observed, with a Y-shape being the least common. Regarding the orientation of the canal, slanted canals are more prevalent, whereas vertically curved canals are rare. Typically, 2 canal openings are observed, with 4 openings being the least common.</p><p><strong>Conclusion: </strong>The current study highlights the challenges associated with identifying the anatomical appearance and variations of the NPC. Consequently, possessing a thorough understanding of this anatomy is essential before undertaking any surgical procedures, such as implant placement. This knowledge helps prevent complications such as nerve injury-related loss of sensation, bleeding due to blood vessel injury, and the development of a nasopalatine duct cyst following trauma to the canal during surgery.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical evaluation of implants placed within or beyond the boundaries of the alveolar ridge preservation: a retrospective case series with 10 weeks of observations in 28 patients. 牙槽嵴保留范围内外植入种植体的临床评估:对 28 名患者进行为期 10 周观察的回顾性病例系列。
IF 2.2 4区 医学
Journal of Periodontal and Implant Science Pub Date : 2024-07-10 DOI: 10.5051/jpis.2400800040
Young-Chang Ko, Ki-Tae Koo, Ling Li, Dongseob Lee, Yong-Moo Lee, Yang-Jo Seol, Tae-Hyung Kim, Jungwon Lee
{"title":"Clinical evaluation of implants placed within or beyond the boundaries of the alveolar ridge preservation: a retrospective case series with 10 weeks of observations in 28 patients.","authors":"Young-Chang Ko, Ki-Tae Koo, Ling Li, Dongseob Lee, Yong-Moo Lee, Yang-Jo Seol, Tae-Hyung Kim, Jungwon Lee","doi":"10.5051/jpis.2400800040","DOIUrl":"https://doi.org/10.5051/jpis.2400800040","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the effect of implant vertical positioning within alveolar ridge preservation (ARP) sites on implant stability quotient (ISQ) values, which were measured 10 weeks post-implantation.</p><p><strong>Methods: </strong>Patients who underwent ARP using collagenized deproteinized bovine bone mineral, followed by implant placement in the posterior area, were divided into 2 groups: the within-ARP group and the beyond-ARP group. In the within-ARP group, osteotomy and implant placement occurred within the ARP boundary. In contrast, in the beyond-ARP group, these procedures were performed beyond the ARP boundary, incorporating 3 mm of pristine bone at the implant's apex. Bone quality was assessed by tactile sense, and both insertion torque during implant surgery and ISQ values at 10 weeks post-implant surgery were measured. Multiple linear regression analysis and Pearson correlation analysis were used to explore the relationship between insertion torque and ISQ values.</p><p><strong>Results: </strong>In total, 30 ARP sites in 28 patients were analyzed. There was no significant difference in bone quality, as determined by tactile sense, between the within-ARP and beyond-ARP groups. At the time of implant placement, the beyond-ARP group exhibited a higher insertion torque (33.33±13.39 Ncm) compared to the within-ARP group (17.08±11.17 Ncm). However, the ISQ values were similar between the 2 groups 10 weeks after implant placement. A positive correlation between insertion torque and ISQ values was confirmed at 10 weeks post-implant.</p><p><strong>Conclusions: </strong>The engagement of pristine bone may facilitate high insertion torque during the placement of implants in ARP sites. Nevertheless, by 10 weeks post-implantation, the ISQ values were found to be comparable, irrespective of the implant's position.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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