{"title":"Microcatheter-assisted trabeculotomy in the treatment of primary congenital glaucoma: Current perspectives.","authors":"Ahmed Al Habash, Wael Otaif","doi":"10.4103/sjopt.sjopt_313_24","DOIUrl":"10.4103/sjopt.sjopt_313_24","url":null,"abstract":"<p><p>Microcatheter-assisted trabeculotomy (MAT) heralds a promising shift in the surgical management of primary congenital glaucoma (PCG). This structured review delves into MAT's significance in PCG treatment, emphasizing its efficacy, surgical technique, indications, and potential complications. MAT presents improved intraocular pressure control, even in complex cases of prior surgical failure, rendering it a valuable therapeutic avenue for preserving vision in pediatric patients with PCG.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"38 4","pages":"316-321"},"PeriodicalIF":0.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-term surgical results and comparison in childhood glaucoma.","authors":"Abdülcemal Gürpınar, Nurşen Arıtürk","doi":"10.4103/sjopt.sjopt_110_24","DOIUrl":"10.4103/sjopt.sjopt_110_24","url":null,"abstract":"<p><strong>Purpose: </strong>Comparison of visual and anatomical results according to surgery types in patients with primary congenital glaucoma (PCG), secondary childhood glaucoma, and glaucoma following cataract surgery (GFCS).</p><p><strong>Methods: </strong>The medical records of pediatric glaucoma patients from 2005 to 2023 at the Ondokuz Mayis University Ophthalmology Clinic were retrospectively reviewed. Participants were classified as undergoing trabeculectomy (TRAB), Ahmed glaucoma valve (AGV) implant, combined TRAB and trabeculotomy (CTT); AGV implant after failed TRAB surgeries (TRAB + AGV). Enrolled patients included PCG, secondary childhood glaucoma, and GFCS groups classified according to the Congenital Glaucoma Research Network guidelines. The groups were analyzed for success rate of surgery, visual acuity (VA), corneal diameter, corneal thickness, intraocular pressure (IOP), number of medications, and refractive errors.</p><p><strong>Results: </strong>Sixty eyes of 38 patients with a mean age of 10.5 ± 6.1 years were included in the study. The final IOP was 16.9 ± 7.4, and the final VA was 0.68 ± 0.66 logMAR. The groups had similar final IOP, cup-to-disc ratio, and complications. The CTT group had the highest overall success rate at 91.7%, whereas the AGV implant group had the lowest at 50%. The final horizontal corneal diameter was 12.6-1.29 mm in the CTT group, 12.62-1.04 mm in the TRAB group (the lowest), and 13.72-0.93 mm in the AGV implant group (the highest) (<i>P</i> = 0.009). The proportion of patients with good VA at the final follow-up was highest in the CTT group at 50%.</p><p><strong>Conclusion: </strong>Various procedures can achieve effective IOP control in most patients. Childhood glaucoma requires long-term close follow-up for a good visual and anatomical prognosis. Considering the success rate and visual prognosis of CTT in childhood glaucoma, it may be a good choice as first-line surgery.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"38 4","pages":"360-367"},"PeriodicalIF":0.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anneleen H J Verhelst, Vincent L E Walgrave, Jan V Eijgen, Sophie Lemmens
{"title":"Reversal of cup-to-disc ratio following trabeculectomy using optical coherence tomography imaging: A case series.","authors":"Anneleen H J Verhelst, Vincent L E Walgrave, Jan V Eijgen, Sophie Lemmens","doi":"10.4103/sjopt.sjopt_165_24","DOIUrl":"10.4103/sjopt.sjopt_165_24","url":null,"abstract":"<p><p>In this case series, we report the reversal of optic disc cupping in three adults following trabeculectomy. Two patients experienced asymptomatic low intraocular pressure (IOP) postoperatively, while the third patient had intermittently elevated IOP for a month. The reversal of cupping, a rare occurrence in adults, was confirmed through optic disc photography and the use of spectral domain-optical coherence tomography (SD-OCT) imaging, which enhances the objectivity of these findings. Despite these changes in cup-to-disc ratio (C/D), there were no significant changes in visual field indices in any of the patients. This series is SD-OCT documented cases of cupping reversal in adults up to 2 years postoperatively.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"38 4","pages":"391-395"},"PeriodicalIF":0.6,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meindert Lauwers, Evelien Vandewalle, Sophie Lemmens
{"title":"Home iCare - What we already know.","authors":"Meindert Lauwers, Evelien Vandewalle, Sophie Lemmens","doi":"10.4103/sjopt.sjopt_138_24","DOIUrl":"10.4103/sjopt.sjopt_138_24","url":null,"abstract":"<p><p>The only known modifiable risk factor for the development and progression of glaucoma is an increased intraocular pressure (IOP). Current follow-up with Goldmann applanation tonometry (GAT) constitutes a suboptimal approach, given out-of-office IOP peaks and fluctuations will not be exposed. Self-tonometry in the home environment could address this unmet need, detecting uncontrolled disease and potentially impacting further therapeutic management. Since recently, iCare HOME was developed as a handheld rebound tonometer for this purpose. The aim of this literature review is twofold. First, the accuracy of iCare HOME compared to GAT will be assessed, including evaluation of the influence of corneal characteristics and the mean IOP. Second, an overview of the reported feasibility and acceptance on the use of iCare HOME will be presented. The literature review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Literature was searched on Medline (via Pubmed), Embase, Cochrane Library, and Web of Science (Core Collection) on April 10, 2023. A total of 187 records were identified after deduplication, of which 20 articles were included after full evaluation of their suitability. This study reported that iCare HOME has a moderate to good accuracy compared to GAT and a tendency to underestimate GAT, with a median underestimation of 1 mmHg, ranging from 2.66 mmHg underestimation to 2.08 mmHg overestimation. Success rates ranged between 67.5% and 100% with a median rate of 82.5%. Sufficient acceptance was demonstrated. In conclusion, self-tonometry with iCare HOME constitutes an accurate, feasible, and accepted method for home monitoring of glaucoma, providing additional out-of-office IOP-data, and increasing patient empowerment.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"38 4","pages":"295-305"},"PeriodicalIF":0.6,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Outcomes of microcatheter-assisted trabeculotomy in adult patients with primary congenital glaucoma and juvenile open-angle glaucoma: A case series.","authors":"Ine Schreurs, Ingeborg Stalmans, Sophie Lemmens","doi":"10.4103/sjopt.sjopt_160_24","DOIUrl":"10.4103/sjopt.sjopt_160_24","url":null,"abstract":"<p><p>Trabeculotomy is conventionally performed using a rigid probe, allowing for 180° trabeculotomy. More recently, microcatheter-assisted 360° trabeculotomy (MCAT) has shown safe and effective results in pediatric glaucoma cases, particularly in primary congenital glaucoma (PCG) and to a lesser extent in juvenile open-angle glaucoma (JOAG). This case report highlights the successful intraocular pressure (IOP) control following iTrack<sup>®</sup>-assisted trabeculotomy in one adult with PCG and two with JOAG. Four eyes of three adults, aged 50, 28, and 45 years, underwent MCAT for uncontrolled PCG or JOAG, with no prior surgical history. No major complications were observed. Postoperatively, IOP ranging from 11 to 15 mmHg was achieved without the need for topical therapy or reoperation during a follow-up period of 12-14 months. These cases suggest that MCAT is both effective and safe for adults with PCG or JOAG requiring surgery.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"38 4","pages":"387-390"},"PeriodicalIF":0.6,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luca De Simone, Chiara Marvisi, Caterina Ricordi, Fabrizio Gozzi, Elena Bolletta, Pietro Gentile, Francesco Muratore, Luca Cimino, Carlo Salvarani
{"title":"Interdisciplinary approach in the management of visual loss in giant cell arteritis.","authors":"Luca De Simone, Chiara Marvisi, Caterina Ricordi, Fabrizio Gozzi, Elena Bolletta, Pietro Gentile, Francesco Muratore, Luca Cimino, Carlo Salvarani","doi":"10.4103/sjopt.sjopt_236_24","DOIUrl":"10.4103/sjopt.sjopt_236_24","url":null,"abstract":"<p><p>Giant cell arteritis (GCA) is the most common vasculitis among older patients in western countries. A correct diagnosis permits the prompt initiation of glucocorticoids, which still represent the cornerstone of treatment. One of the most feared complications of the disease is sudden visual loss and other ischemic events causing visual disturbances. In these cases, an interdisciplinary approach between ophthalmologists and rheumatologists is crucial to avoiding any diagnostic delays and to permitting correct clinical assessment without subjecting the patient to unnecessary treatment. In this review, we discuss the main causes of visual disturbances in GCA, particularly the causes of sight loss, outlining the red flags that should raise suspicion in ophthalmologists and rheumatologists.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"14-19"},"PeriodicalIF":0.6,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Labay-Tejado, Néstor Ventura-Abreu, Sofía Porto-Castro, Ainhoa D Castellarnau, M Jesús Muniesa, Elena Millá, Marta Pazos
{"title":"Early safety and efficacy outcomes of the PAUL glaucoma implant in a Spanish population: A retrospective study.","authors":"Sara Labay-Tejado, Néstor Ventura-Abreu, Sofía Porto-Castro, Ainhoa D Castellarnau, M Jesús Muniesa, Elena Millá, Marta Pazos","doi":"10.4103/sjopt.sjopt_164_24","DOIUrl":"10.4103/sjopt.sjopt_164_24","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the study was to evaluate the efficacy and safety of the PAUL glaucoma implant (PGI) in refractory glaucoma patients, during the early postoperative period.</p><p><strong>Methods: </strong>We conducted a retrospective, cohort study of patients that had received a PGI between February 2022 and December 2023. An intraluminal polypropylene suture was placed to prevent early hypotony in all cases. Demographics, intraocular pressure (IOP), and medication variation were evaluated for up to 6 months. The success rate was stratified into <18 mmHg and 30% from baseline or <15 mmHg and 40% IOP reduction. The safety outcomes were also analyzed.</p><p><strong>Results: </strong>Sixteen eyes from 16 patients were included in the analysis. Fifteen of them had had a previous surgical glaucoma procedure. At 6 months, IOP decreased from 26.6 (±6.2) to 15.3 (±4.6) mmHg, with fewer glaucoma medications, from a median (interquartile range) of 3 (2-3) - 1.5 (0-2) (<i>P</i> < 0.005). Twelve (75%) and seven (43.8%) eyes met the qualified and complete success definition for the first category, and eight (50%) and four (25%) met the second criterion. One case with self-limiting choroidal detachments, but >6 mmHg IOP was found in our cohort.</p><p><strong>Conclusion: </strong>The PGI seems to be safe and effective from the early postoperative period. The IOP reduction rate could make it suitable for patients with refractory moderate-to-advanced glaucoma.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"38 4","pages":"368-373"},"PeriodicalIF":0.6,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miguel Santos, Afonso Lima-Cabrita, Rafael Barão, Luís Abegão-Pinto
{"title":"Detection of iridocorneal angle changes after uncomplicated phacoemulsification using automated gonioscopy imaging.","authors":"Miguel Santos, Afonso Lima-Cabrita, Rafael Barão, Luís Abegão-Pinto","doi":"10.4103/sjopt.sjopt_141_24","DOIUrl":"10.4103/sjopt.sjopt_141_24","url":null,"abstract":"<p><strong>Purpose: </strong>Phacoemulsification cataract surgery (PCS) is known to change anterior chamber morphology, widening the iridocorneal angle (ICA) of most patients. This study aims to determine whether automated gonioscopy imaging (AGI) with GS-1<sup>®</sup> (NIDEK CO., Japan) can detect changes in ICA morphology and pigmentation after PCS.</p><p><strong>Methods: </strong>A prospective, observational study including patients who underwent PCS at Hospital Santa Maria, Lisbon, from March to October 2022. AGI was done at the preoperative visit and 6-weeks postoperative. The images were analyzed using NAVIS-EX Software (NIDEK CO., Japan) by a masked observer. Each eye was divided into four quadrants and their morphology and pigmentation was graded according to the Shaffer and modified Scheie classifications, respectively.</p><p><strong>Results: </strong>Twenty-two eyes from 21 patients (62% female) were included, with a mean age of 74.5 ± 7.9 years. Baseline AGI identified 7 (33%) patients with angle closure. PCS led to all patients achieving open angle status and lower preoperative Shaffer grades achieved greater postoperative improvement. Statistically significant ICA widening was found in the superior (<i>P</i> = 0.004), inferior (<i>P</i> = 0.008), and temporal (<i>P</i> = 0.023) quadrants, but not the nasal quadrant (<i>P</i> = 0.21). Similarly, a statistically significant pigmentation increase was found in the superior (<i>P</i> = 0.008), inferior (<i>P</i> = 0.002), and temporal (<i>P</i> = 0.016) quadrants and less pigmented baseline quadrants showed a greater gain. The most significant pigmentation gain was in the inferior quadrant.</p><p><strong>Conclusion: </strong>Unlike other imaging modalities, AGI with GS-1 can detect changes in ICA morphology and pigmentation after routine cataract surgery, mainly in the superior, inferior, and temporal quadrants.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"38 4","pages":"348-351"},"PeriodicalIF":0.6,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pediatric keratoconus in a tertiary eye hospital in Eastern province, Saudi Arabia: Patient characteristics and management outcomes.","authors":"Asma Alhazmi, Abdulaziz Alsomali, Saad Algarni, Arwa Althumairi","doi":"10.4103/sjopt.sjopt_169_24","DOIUrl":"10.4103/sjopt.sjopt_169_24","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigates pediatric keratoconus in a tertiary eye hospital in Eastern Province, Saudi Arabia, aiming to understand the presenting features and treatment outcomes in this high-prevalence region. The research addresses pediatric keratoconus clinical profile and management strategies.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted from 2022 to 2023, reviewing medical records of pediatric keratoconus patients. Demographic data, clinical characteristics, risk factors, presenting symptoms, and treatment outcomes were recorded. Severity staging was performed based on Amsler-Krumeich's classification.</p><p><strong>Results: </strong>The study included 218 eyes from 109 pediatric keratoconus patients, with 65% of male and 35% of female patients. Decreased vision was the most common symptom (92%), and risk factors included a family history of keratoconus (9%) and vernal keratoconjunctivitis (6%). Stage 1 was the most frequent in both age groups (<14 years and ≥ 14 years). Treatment strategies included corneal collagen cross-linking (CXL), hard contact lenses, corneal rings, deep anterior lamellar keratoplasty (DLK), and penetrating keratoplasty. Significant improvements were observed in visual acuity, refractive errors, and tomographic parameters following these interventions.</p><p><strong>Conclusion: </strong>This study provides valuable insights into pediatric keratoconus in Saudi Arabia, emphasizing the importance of early diagnosis and interventions for better outcomes. Larger, multicenter prospective studies are essential for a comprehensive understanding of pediatric keratoconus and its optimal management. The findings contribute to the knowledge base and guide future research to improve patient quality of life.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"38 3","pages":"261-267"},"PeriodicalIF":0.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11503975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}