Saudi Journal of Ophthalmology最新文献

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Predictors for postpenetrating keratoplasty astigmatism: A retrospective cohort study. 穿透性角膜移植术后散光的预测因素:一项回顾性队列研究。
IF 0.6
Saudi Journal of Ophthalmology Pub Date : 2025-02-07 eCollection Date: 2025-01-01 DOI: 10.4103/sjopt.sjopt_88_22
Mouna Al Saad, Amin Shehadeh, Saif A AlRyalat, Tima Khawaldeh, Rhagad Shaqqour, Ruqaya Al-Ani, Sereen B Alqhaiwi, Amal Shehadeh, Lina Wahbeh, Hamzeh M Alrawashdeh
{"title":"Predictors for postpenetrating keratoplasty astigmatism: A retrospective cohort study.","authors":"Mouna Al Saad, Amin Shehadeh, Saif A AlRyalat, Tima Khawaldeh, Rhagad Shaqqour, Ruqaya Al-Ani, Sereen B Alqhaiwi, Amal Shehadeh, Lina Wahbeh, Hamzeh M Alrawashdeh","doi":"10.4103/sjopt.sjopt_88_22","DOIUrl":"10.4103/sjopt.sjopt_88_22","url":null,"abstract":"<p><strong>Purpose: </strong>To identify the possible predicting factors for developing astigmatism following penetrating keratoplasty, namely age, gender, laterality, preoperative indication for surgery, size of donor and recipient graft, and selective versus total sutures removal. Moreover, the duration of postoperative topical steroids use and if that surgery was the first graft or a redo surgery.</p><p><strong>Methods: </strong>A retrospective cohort study which included data of patients who underwent penetrating keratoplasty at the University of Jordan Hospital. Multiple local and systemic perioperative risk factors were evaluated concerning developing postoperative astigmatism.</p><p><strong>Results: </strong>Three hundred and ninety-two eyes were included. Of those, 38.8% developed postoperative significant astigmatism. Significant astigmatism postkeratoplasty was found to be affected by preoperative diagnosis with corneal dystrophy being the most common indication associated with significant postoperative astigmatism. Significant astigmatism was significantly correlated with long-term topical steroid use, longer follow-up duration, and the first keratoplasty (<i>P</i> < 0.001). No correlation was found between significant astigmatism, age, and the time of suture removal.</p><p><strong>Conclusion: </strong>Determination of the factors that influence the development of significant astigmatism is crucial. A long-term follow-up is necessary as the incidence of significant astigmatism increases with time.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"60-64"},"PeriodicalIF":0.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New technique for enhancing the astigmatic correction of intracorneal ring segments in keratoconus eyes with a central cone. 带中心锥体圆锥角膜环段增强散光矫正的新技术。
IF 0.6
Saudi Journal of Ophthalmology Pub Date : 2025-02-07 eCollection Date: 2025-01-01 DOI: 10.4103/sjopt.sjopt_22_23
Yara Bteich, Carl-Joe Mehanna, Maamoun A Fattah, Alain Saad, Rafic Antonios, Marc Nasser, Shady T Awwad
{"title":"New technique for enhancing the astigmatic correction of intracorneal ring segments in keratoconus eyes with a central cone.","authors":"Yara Bteich, Carl-Joe Mehanna, Maamoun A Fattah, Alain Saad, Rafic Antonios, Marc Nasser, Shady T Awwad","doi":"10.4103/sjopt.sjopt_22_23","DOIUrl":"10.4103/sjopt.sjopt_22_23","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to present a case series describing a new simple technique of intrastromal corneal ring segment (ICRS) implantation that shortens the effective arc length of a segment and amplifies its effect on the corneal cylinder.</p><p><strong>Methods: </strong>A 150° ICRS designed to be implanted in the 6-mm optical zone (OZ) (Intacs<sup>®</sup> SK) was instead implanted in a 7-mm OZ channel using a femtosecond laser.</p><p><strong>Results: </strong>The decrease in manifest refraction spherical equivalent (MRSE) at 6 months was significantly less for the SK-7 group compared to the SK-6 group (2.21 ± 0.86 D vs. 8.87 ± 3.22 D, <i>P</i> = 0.004, respectively). The average central corneal power was also more pronounced in the SK-6 group (-2.19 ± 0.98D vs. -4.50 ± 2.87D, <i>P</i> = 0.20, respectively). Greater reduction in corneal and refractive cylinder magnitude (SimK) and vector was observed when Intacs<sup>®</sup> SK segments were implanted at 7-mm instead of 6-mm OZ. The SK-7 group gained more Corrected distance visual acuity (CDVA) lines at 6 months. The vector analysis variables including surgically induced astigmatic vector, difference vector, correction index, and index of success were all better when Intacs<sup>®</sup> SK was implanted at 7 mm.</p><p><strong>Conclusion: </strong>Shortening the effective arc length of the ICRS to 129° resulted in greater astigmatism correction with less effect on overall corneal flattening and MRSE. This technique would allow the surgeon to obtain a different effective ICRS arc length from the actual one and can be useful to reduce the inventory of ICRS in a given center.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"54-59"},"PeriodicalIF":0.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review on anterior uveitis and spondyloarthritis with a focus on the interdisciplinary approach between ophthalmologists and rheumatologists. 回顾前葡萄膜炎和脊椎关节炎,重点是眼科医生和风湿病学家之间的跨学科方法。
IF 0.6
Saudi Journal of Ophthalmology Pub Date : 2025-01-02 eCollection Date: 2025-01-01 DOI: 10.4103/sjopt.sjopt_240_24
Elena Bolletta, Filippo Crescentini, Pietro Gentile, Giorgia Citriniti, Pierluigi Macchioni, Antonio Marchesoni, Luca De Simone, Fabrizio Gozzi, Carlo Salvarani, Luca Cimino
{"title":"A review on anterior uveitis and spondyloarthritis with a focus on the interdisciplinary approach between ophthalmologists and rheumatologists.","authors":"Elena Bolletta, Filippo Crescentini, Pietro Gentile, Giorgia Citriniti, Pierluigi Macchioni, Antonio Marchesoni, Luca De Simone, Fabrizio Gozzi, Carlo Salvarani, Luca Cimino","doi":"10.4103/sjopt.sjopt_240_24","DOIUrl":"10.4103/sjopt.sjopt_240_24","url":null,"abstract":"<p><p>Anterior uveitis (AU) is characterized by the inflammation of the iris and ciliary body and is the most frequent extra-articular manifestation of spondyloarthritis (SpA). In SpA patients, AU is typically described as unilateral alternating acute AU (AAU). Moreover, as AAU can be the initial clinical manifestation of SpA, ophthalmologists could play a key role in the early diagnosis of SpA. The diagnostic delay in SpA is associated with poorer outcomes, including functional impairment, reduced response to treatment, and lower quality of life. A well-structured screening of patients with AAU could facilitate the early diagnosis. Consequently, the interdisciplinary collaboration between ophthalmologists and rheumatologists is fundamental to reduce the diagnostic delays. A correct and early diagnosis of SpA, together with early treatment initiation is important prognostic factors. These measures are associated with better treatment responses and may help retard the development of structural damage, particularly in the era of biological therapies, which have significantly improved the care of patients with SpA. Although various algorithms have been proposed to guide the selection of appropriate candidates for rheumatology referral, to date, there are no formal guidelines or universally recognized criteria for referral. This review aimed to summarize the epidemiological, pathogenetic, clinical, and therapeutic aspects of AU associated with SpA as well as the ophthalmology-rheumatology interdisciplinary approach.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"20-30"},"PeriodicalIF":0.6,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Juvenile idiopathic arthritis and associated uveitis: A review of pathogenesis, diagnosis, and management. 青少年特发性关节炎和相关的葡萄膜炎:发病机制、诊断和治疗的综述。
IF 0.6
Saudi Journal of Ophthalmology Pub Date : 2025-01-02 eCollection Date: 2025-01-01 DOI: 10.4103/sjopt.sjopt_153_24
Costanza Barresi, Francesco Baldo, Matteo Menean, Achille Marino, Stefania Costi, Cecilia B Chighizola, Roberto F Caporali, Elisabetta Miserocchi
{"title":"Juvenile idiopathic arthritis and associated uveitis: A review of pathogenesis, diagnosis, and management.","authors":"Costanza Barresi, Francesco Baldo, Matteo Menean, Achille Marino, Stefania Costi, Cecilia B Chighizola, Roberto F Caporali, Elisabetta Miserocchi","doi":"10.4103/sjopt.sjopt_153_24","DOIUrl":"10.4103/sjopt.sjopt_153_24","url":null,"abstract":"<p><p>Juvenile idiopathic arthritis (JIA) is the most common rheumatologic disorder in children, posing significant physical and emotional challenges due to its chronic nature and the need for prolonged immunosuppressive therapies. Uveitis is the most common extra-articular manifestation of JIA, and it can be a sight-threatening condition. Despite advances in biologic treatments, JIA continues to present substantial therapeutic challenges, necessitating multiple treatment attempts and close monitoring for secondary failures. JIA-associated uveitis remains one of the most challenging and aggressive types of uveitis, particularly in children, due to its early onset, chronicity, and limited therapeutic responses despite new treatments. Early recognition and prompt treatment of both arthritis and uveitis are essential for achieving sustained remission and preventing complications. Effective management of JIA-uveitis requires a collaborative approach between pediatric rheumatologists and ophthalmologists to ensure timely assessments, regular screenings, and necessary therapy adjustments. This integrated care approach is crucial for achieving optimal outcomes. Therefore, this review aims to extensively analyze the pathogenesis, diagnosis, and therapy of JIA and its associated uveitis.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"31-40"},"PeriodicalIF":0.6,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dry eye and systemic diseases. 干眼和全身性疾病。
IF 0.6
Saudi Journal of Ophthalmology Pub Date : 2025-01-02 eCollection Date: 2025-01-01 DOI: 10.4103/sjopt.sjopt_182_24
Andrea Leonardi, Antonio Di Zazzo, Francesco Cutrupi, Luca Iaccarino
{"title":"Dry eye and systemic diseases.","authors":"Andrea Leonardi, Antonio Di Zazzo, Francesco Cutrupi, Luca Iaccarino","doi":"10.4103/sjopt.sjopt_182_24","DOIUrl":"10.4103/sjopt.sjopt_182_24","url":null,"abstract":"<p><p>Tear film instability and reduced tear production initiate a vicious circle where hyperosmolarity, ocular inflammation, and apoptosis may induce a damage of the ocular surface including keratitis which is all included in a common condition called dry eye disease (DED). DED can be apparently an isolated ocular surface condition; however, multiple ocular and systemic risk factors have been identified. The association with systemic diseases such as autoimmune diseases, hormonal imbalance, dietary imbalance, metabolic diseases, infections, psychological conditions, and aging together with external causative factors may act independently or interacting each other to initiate and/or perpetuate signs and symptoms typical of this very common ocular surface disease. Rheumatological disorders are most typically associated with dry eye; therefore, strict interaction with rheumatologists is important for the diagnosis and management of DED patients. In the present narrative review, we highlight associations between DED and some of the systemic disorders that may be implicated in the development of the disease.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"5-13"},"PeriodicalIF":0.6,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ab externo Schlemm's canal surgery: Efficacy and safety outcomes. 外施勒姆氏管手术:疗效和安全性。
IF 0.6
Saudi Journal of Ophthalmology Pub Date : 2024-12-26 eCollection Date: 2024-10-01 DOI: 10.4103/sjopt.sjopt_159_24
Gaël Batailde, Alicia V Ginderachter, Jan V Eijgen, Gordana Sunaric-Mégevand, Ingeborg Stalmans, Sophie Lemmens
{"title":"Ab externo Schlemm's canal surgery: Efficacy and safety outcomes.","authors":"Gaël Batailde, Alicia V Ginderachter, Jan V Eijgen, Gordana Sunaric-Mégevand, Ingeborg Stalmans, Sophie Lemmens","doi":"10.4103/sjopt.sjopt_159_24","DOIUrl":"10.4103/sjopt.sjopt_159_24","url":null,"abstract":"<p><p>The purpose of this article is to review the existing literature on the efficacy and safety of ab externo viscocanalostomy (VCS) and canaloplasty (CP) in glaucoma patients. A literature search was conducted, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 Statement Criteria, in Medline (via PubMed), Embase (Ovid), Web of Science (Clarivate Analytics) and Cochrane Library (Cochrane). Wherever possible, level of evidence has been assessed by means of the oxford center for evidence-based medicine level of evidence classification. Twenty-nine articles were included providing data for 2790 subjects. The mean preoperative medicated intraocular pressure (IOP) was 25.06 ± 5.29 mmHg in the CP group and 36.22 ± 11.20 mmHg in the VCS group. The mean postoperative IOP was 14.98 ± 1.28 mmHg in the CP group and 15.17 ± 1.34 mmHg in the VCS group at 36 months of follow-up. CP and VCS showed a mean IOP reduction from baseline of 40.21% and 58.12%, respectively, and medication reduction of 72.37% and 81.01%, respectively, after 36 months of follow-up. Perforation of the trabeculo-descemetic membrane was reported in 5.39% (CP group) and in 8.24% (VCS group) of cases (micro) hyphema was the most reported postoperative complication. CP and VCS significantly reduce IOP and medication use. The incidence of complications seen in filtration surgery is minimized by these nonpenetrating and bleb-independent approaches. With its efficacy and high safety profile, Schlemm's canal surgery is a valuable alternative to penetrating glaucoma filtration surgery.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"38 4","pages":"322-331"},"PeriodicalIF":0.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute corneal edema and residual subepithelial haze after bilateral selective laser trabeculoplasty: A case series. 双侧选择性激光小梁成形术后急性角膜水肿和残余上皮下混浊:一个病例系列。
IF 0.6
Saudi Journal of Ophthalmology Pub Date : 2024-12-26 eCollection Date: 2024-10-01 DOI: 10.4103/sjopt.sjopt_152_24
Jeffrey Nijs, Evelien Vandewalle, Ingeborg Stalmans, Sophie Lemmens
{"title":"Acute corneal edema and residual subepithelial haze after bilateral selective laser trabeculoplasty: A case series.","authors":"Jeffrey Nijs, Evelien Vandewalle, Ingeborg Stalmans, Sophie Lemmens","doi":"10.4103/sjopt.sjopt_152_24","DOIUrl":"10.4103/sjopt.sjopt_152_24","url":null,"abstract":"<p><p>The primary objective of this case series is to report three cases of acute corneal edema and subepithelial haze occurring shortly after bilateral selective laser trabeculoplasty (SLT). SLT was performed to treat open-angle glaucoma in three female, middle-aged patients who subsequently manifested stromal haze within 24-48 h following the procedure. The patients were, therefore, treated with topical steroids for several weeks. Due to uncontrolled intraocular pressure, one patient underwent a trabeculectomy. The corneal edema resolved in all three patients. However, they exhibited a hyperopic shift, along with alterations in corneal astigmatism. The incidence of corneal edema and subepithelial haze following SLT is an exceedingly rare phenomenon. While certain factors are hypothesized to contribute to this complication, the predisposing factors leading to corneal changes following this laser procedure remain unclear.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"38 4","pages":"396-400"},"PeriodicalIF":0.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visual field patterns in glaucoma: A systematic review. 青光眼的视野模式:系统综述。
IF 0.6
Saudi Journal of Ophthalmology Pub Date : 2024-12-26 eCollection Date: 2024-10-01 DOI: 10.4103/sjopt.sjopt_143_24
Marlies F Vandersnickt, Jan van Eijgen, Sophie Lemmens, Ingeborg Stalmans, Luís A Pinto, Evelien M Vandewalle
{"title":"Visual field patterns in glaucoma: A systematic review.","authors":"Marlies F Vandersnickt, Jan van Eijgen, Sophie Lemmens, Ingeborg Stalmans, Luís A Pinto, Evelien M Vandewalle","doi":"10.4103/sjopt.sjopt_143_24","DOIUrl":"10.4103/sjopt.sjopt_143_24","url":null,"abstract":"<p><p>The aim of this literature study is to investigate the specific visual field defects for each glaucoma subtype and evaluate their pattern of progression. A systematic search was performed in accordance with the PRISMA guidelines in Medline (via PubMed), Embase, Web of Science, and the Cochrane Library on January 23, 2024. The literature search identified 3332 records after deduplication. Sixty-nine articles were included after screening and assessment for eligibility. Specific visual field patterns for primary open-angle glaucoma, normal-tension glaucoma, primary angle-closure glaucoma, and juvenile open-angle glaucoma were summed up. Since the search results on visual field progression only covered primary open-angle glaucoma and normal-tension glaucoma, the further analysis was confined to these glaucoma subtypes. This systematic review summarizes the literature concerning visual field patterns in glaucoma for the ophthalmologist.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"38 4","pages":"306-315"},"PeriodicalIF":0.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-term safety and efficacy of ripasudil as "add-on therapy" in glaucoma patients on maximum tolerable glaucoma medication. 利帕舒地尔作为青光眼患者最大耐受青光眼药物“附加治疗”的短期安全性和有效性。
IF 0.6
Saudi Journal of Ophthalmology Pub Date : 2024-12-26 eCollection Date: 2024-10-01 DOI: 10.4103/sjopt.sjopt_201_24
Rashmi Kumari, Bhawesh C Saha, Anita Ambasta, Vidya B Kumar
{"title":"Short-term safety and efficacy of ripasudil as \"add-on therapy\" in glaucoma patients on maximum tolerable glaucoma medication.","authors":"Rashmi Kumari, Bhawesh C Saha, Anita Ambasta, Vidya B Kumar","doi":"10.4103/sjopt.sjopt_201_24","DOIUrl":"10.4103/sjopt.sjopt_201_24","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to evaluate the additional intraocular pressure (IOP) lowering effect and tolerability of ripasudil in patients with glaucoma inadequately controlled with maximum tolerable medical therapy.</p><p><strong>Methods: </strong>A prospective, noncomparative, interventional case series. Patients with primary open-angle glaucoma (POAG) but IOP inadequately controlled with maximum medical therapy were enrolled for this. Ripasudil (0.4%) was added as adjunctive therapy to the ongoing glaucoma treatment. The primary outcome was the mean IOP reduction after 3 months of treatment, whereas the secondary outcome was the percentage attainment of predefined target IOP and the incidence of any adverse events.</p><p><strong>Results: </strong>A total of 42 eyes of 42 patients with POAG were evaluated. Mean number of medications at the time of enrolment was 3.54 ± 0.45. The percentage IOP reduction from baseline was 16.8% with a 95% confidence interval, mean IOP reduction was - 2.9 mm Hg (range: -1.9--4.6) with <i>P</i> < 0.001 after 3 months of treatment. Eighteen eyes (42.8%) were able to achieve the target IOP. Notable adverse event was conjunctival hyperemia in 57.14% and blepharitis in 2.38% of the eyes but they were mild and transient.</p><p><strong>Conclusion: </strong>Ripasudil is effective and tolerable in POAG patients already on maximal medical therapy. It can be utilized as an extra tool that can postpone invasive procedures, especially in the short term.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"38 4","pages":"343-347"},"PeriodicalIF":0.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glaucoma surgery success and corneal graft survival in patients with prior corneal transplantation: A retrospective cohort study. 既往角膜移植患者青光眼手术成功和角膜移植存活:一项回顾性队列研究。
IF 0.6
Saudi Journal of Ophthalmology Pub Date : 2024-12-26 eCollection Date: 2024-10-01 DOI: 10.4103/sjopt.sjopt_166_24
Elena Brotons-Muñoz, Néstor Ventura-Abreu, María J Muniesa, Elena Millá, Josep Torras-Sanvicens, Marta Pazos
{"title":"Glaucoma surgery success and corneal graft survival in patients with prior corneal transplantation: A retrospective cohort study.","authors":"Elena Brotons-Muñoz, Néstor Ventura-Abreu, María J Muniesa, Elena Millá, Josep Torras-Sanvicens, Marta Pazos","doi":"10.4103/sjopt.sjopt_166_24","DOIUrl":"10.4103/sjopt.sjopt_166_24","url":null,"abstract":"<p><strong>Purpose: </strong>Elevated intraocular pressure (IOP) following corneal transplantation (CT) presents a significant risk for graft failure and visual impairment. This retrospective cohort study aims to evaluate the outcomes of different glaucoma surgeries and corneal graft survival rates in patients who have undergone CT.</p><p><strong>Methods: </strong>A single-center, retrospective cohort was conducted on all patients at our tertiary hospital who had received glaucoma surgery following corneal transplant surgery from 2020 to 2023. Inclusion criteria were defined as patients over 18 years of age, with at least 6 months of follow-up. The primary outcomes included corneal graft survival and glaucoma surgery success.</p><p><strong>Results: </strong>Twenty eyes from 18 patients who underwent glaucoma procedures after a corneal transplant were analyzed. Glaucoma surgery success - IOP level within limits (>6 mmHg but below the preset target), no further glaucoma surgeries, and no postoperative severe vision loss due to complications - was achieved in 80% of cases, with no significant differences observed among techniques. Corneal graft survival at 6 months (a functional transplant that does not require a regraft procedure and with central graft clarity) was 55%, with higher rates observed in patients undergoing nonpenetrating deep sclerectomy (NPDS), XEN45 gel stent (XGS), or PAUL glaucoma implant (PGI) procedures compared to trabeculectomy and Ahmed valve. Only 35% of patients experienced minor complications, and no major adverse events were reported.</p><p><strong>Conclusion: </strong>In our retrospective cohort study, surgical approaches such as NPDS, XGS, or PGI showed the most favorable outcomes regarding glaucoma surgery success and corneal graft survival rates.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"38 4","pages":"374-379"},"PeriodicalIF":0.6,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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