Saudi Journal of Ophthalmology最新文献

{"title":"A case of choroidal neovascularization following multiple repairs of a rhegmatogenous retinal detachment.","authors":"Dipen Kumar, Jason Zehden, Alice Y Zhang","doi":"10.4103/sjopt.sjopt_137_23","DOIUrl":"10.4103/sjopt.sjopt_137_23","url":null,"abstract":"<p><p>Choroidal neovascularization (CNV) is rare after retinal detachment (RD) surgery. In this retrospective report, we detail a case of CNV after three RD repairs with silicone oil placement for the repair of the most recent redetachment. The patient responded to antivascular endothelial growth factor intravitreal injections with resolution of intraretinal and subretinal fluid. Postoperative optical coherence tomography imaging may be required for patients with risk factors such as multiple surgeries on the same eye, silicone oil, or macular detachment.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"104-106"},"PeriodicalIF":0.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The potential harmfulness of consensus meetings and/or opinion surveys in medicine to determine nosological classifications: The \"white dots\" case.","authors":"Ioannis Papasavvas, Abdulrahman F Albloushi, Masaru Takeuchi, Yoshihiko Usui, Sagnik Sen, Vania Lages, De-Kuang Hwang, Wen-Jung Lo, Marina Papadia, Carl P Herbort","doi":"10.4103/sjopt.sjopt_331_24","DOIUrl":"10.4103/sjopt.sjopt_331_24","url":null,"abstract":"","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"110-111"},"PeriodicalIF":0.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Specific retinal vasculitis in HLA-A29 birdshot retinochoroiditis, distinguishing it from other causes of vasculitis: A pilot study.","authors":"Carl P Herbort, Ioannis Papasavvas","doi":"10.4103/sjopt.sjopt_230_24","DOIUrl":"10.4103/sjopt.sjopt_230_24","url":null,"abstract":"<p><strong>Purpose: </strong>Human leukocyte antigen-A29 (HLA-A29) birdshot retinochoroiditis (BRC) is a noninfectious uveitis affecting independently the retina and the choroid. While the choroidal involvement is characterized by a stromal choroiditis, the retinal features of BRC were less well defined until a recent study determined a specific pattern of retinal involvement with seven features including profuse posterior retinal leakage, thick fluorescein angiography sheathing/staining, profuse disc hyperfluorescence, macular edema with foveal sparing, and circulatory arteriovenous pseudo delay. The aim of this study was to determine whether the specific pattern of retinal involvement was diagnostic for BRC distinguishing it from other causes of retinal vasculitis.</p><p><strong>Methods: </strong>A retrospective comparative study comparing patients diagnosed with BRC to patients with other causes of retinal vasculitis. A score based on seven retinal features was calculated. The maximum possible score was 16. If the score reached ≥ 9, the vasculitis was considered to be compatible with BRC.</p><p><strong>Results: </strong>Eighteen BRC and 18 non-BRC vasculitis were included in the study. The mean age of BRC patients was 49.5 ± 9.1 years, 11/18 females and 7/18 males (female 61%/male 39%). HLA-A29 antigen was present in all patients (100%). The mean age of patients in the control group with non-BRC vasculitis was 37 ± 17, 11/18 females and 7/18 males (female 61%/male 39%). The control group included nine cases of sarcoidosis chorioretinitis, six cases of intermediate uveitis of the pars planitis type, two cases of Behçet uveitis, and one case of tuberculosis chorioretinitis. The mean scores for the BRC group were 10.5 ± 1.7, while in the control group, it was 3.9 ± 2.8 (<i>P</i> < 0.0001, <i>t</i>-test). Using Fisher's exact test, the probability of the scores ≥ 9 to correspond to BRC was significantly different and higher than the scores of the group of non-BRC vasculitis (<i>P</i> < 0.0001). The positive predictive value was high amounting to 88.9%.</p><p><strong>Conclusion: </strong>Retinal vasculitis related to BRC has specific findings leading, if present, to the diagnosis of BRC that should be ascertained by the search of indocyanine green angiography lesions with the ultimate confirmation by the presence of the HLA-A29 antigen.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 2","pages":"192-197"},"PeriodicalIF":0.6,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to letter for article \"Evaluation of neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and mean platelet volume levels in pediatric keratoconus patients\".","authors":"Müge Toprak, Özgül Altıntaş, Özge Yendur, Büşra Yılmaz Tuğan","doi":"10.4103/sjopt.sjopt_321_24","DOIUrl":"https://doi.org/10.4103/sjopt.sjopt_321_24","url":null,"abstract":"","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"113-114"},"PeriodicalIF":0.6,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ophthalmic and periocular management of facial nerve palsy.","authors":"Anthony Yao, Raman Malhotra","doi":"10.4103/sjopt.sjopt_3_25","DOIUrl":"10.4103/sjopt.sjopt_3_25","url":null,"abstract":"<p><p>Facial nerve palsy (FNP) can be a highly distressing condition with sight-threatening sequelae. However, major advances in ophthalmic and oculoplastic management have been achieved in recent decades, guided by a better understanding of clinical manifestations and an ever-expanding armamentarium of surgical and nonsurgical therapies. Ophthalmologists should be aware of the contemporary approach to FNP, its periorbital complications, and the broad range of treatment options now available.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 2","pages":"117-124"},"PeriodicalIF":0.6,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of azathioprine as a first-line therapy in new onset of acute Vogt-Koyanagi-Harada disease in the Indian population.","authors":"Swapnil M Parchand, Tripti Saraogi, Samrat Chatterjee, Anil Gangwe, Deepanshu Agrawal, Deepshikha Agrawal","doi":"10.4103/sjopt.sjopt_200_23","DOIUrl":"10.4103/sjopt.sjopt_200_23","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study is to evaluate the efficacy of azathioprine as a first-line therapy in new onset of acute Vogt-Koyanagi-Harada (VKH) disease in the Indian population.</p><p><strong>Methods: </strong>This retrospective study included 17 (34 eyes) patients who received azathioprine along with systemic steroids for new onset of acute VKH disease and had minimum follow-up of 24 months. Uveitis activity was assessed clinically and by indocyanine green angiography.</p><p><strong>Results: </strong>The mean follow-up period was 27.53 (range: 24-48) months. Corticosteroid-sparing effect was achieved in 14 (82.35%) patients. The median time to achieve the steroid-sparing effect was 3 months (range: 1.5-5 months). Corrected distance visual acuity better than 0.3 logMAR was achieved in 28 (82.35%) eyes. Sunset glow fundus developed in 2 (5.88%) eyes while on azathioprine therapy. None of the eyes developed chronic granulomatous uveitis phase or severe systemic side effect during treatment with azathioprine.</p><p><strong>Conclusion: </strong>Azathioprine as first-line therapy in patients with new onset of acute VKH disease has effective steroid-sparing effect and prevents progression to chronic recurrent granulomatous stage.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"65-70"},"PeriodicalIF":0.6,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Levator surgery with and without tarsectomy for correction of fair-function congenital ptosis: A randomized controlled trial.","authors":"Mostafa M Diab, Taha A Ashraf Taha, Nada K Abdelsattar","doi":"10.4103/sjopt.sjopt_322_24","DOIUrl":"10.4103/sjopt.sjopt_322_24","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose is to compare the functional and cosmetic outcomes of levator resection with tarsoconjunctival mullerectomy (LR plus) versus modified LR (mLR) for correcting congenital ptosis with fair levator function (LF; 4-7 mm).</p><p><strong>Methods: </strong>In this prospective, randomized, controlled, double-blinded trial, 34 children (aged 6-12 years old) with unilateral congenital ptosis and fair LF were randomized to LR plus (<i>n</i> = 16) or mLR group B (<i>n</i> = 18). Margin-reflex distance 1 (MRD1), LF, lagophthalmos, corneal staining (Miyata grading), eyelid crease, contour, and eyelash angle were assessed postoperatively at 1, 3, 6, and 12 months. Outcomes were graded by an independent observer.</p><p><strong>Results: </strong>Both groups demonstrated significant postoperative MRD1 improvements. In the LR plus group, MRD1 increased from 0.56 ± 1.09 mm to 3.44 ± 1.15 mm (<i>P</i> < 0.001), and while in the mLR group, it improved from 0.89 ± 1.18 mm to 4.06 ± 0.94 mm (<i>P</i> < 0.001), with no significant intergroup difference. The mLR group showed significantly greater LF improvement at all-time points (<i>P</i> < 0.001), with a 12-month LF of 11.28 ± 2.16 mm versus 7.38 ± 2.09 mm in the LR plus group. The mLR group had less lagophthalmos, corneal staining (early follow-up), and better eyelid contour at 3, 6, and 12 months. Eyelash ptosis was more frequently observed in the LR plus group. Complications occurred in 3 (18.8%) patients in the LR plus (including exposure keratopathy, recurrence, and suture-related corneal abrasion) and in 1 (5.6%) patient in the mLR group (overcorrection).</p><p><strong>Conclusion: </strong>Both LR plus and mLR are effective for the correction of congenital ptosis with fair LF. However, mLR yielded in greater LF improvement, less postoperative lagophthalmos and corneal complications, and better eyelid contour. Therefore, mLR may be the preferred surgical technique for this condition.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 2","pages":"148-154"},"PeriodicalIF":0.6,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behçet's disease: A review of the ophthalmologic findings reported in Behçet's original descriptions.","authors":"Massimo Accorinti, Marta Gilardi, Michela Cecere, Shigeaki Ohno, Daniele De Geronimo","doi":"10.4103/sjopt.sjopt_216_24","DOIUrl":"10.4103/sjopt.sjopt_216_24","url":null,"abstract":"<p><p>Behçet's disease (BD) is a systemic disease characterized by the onset of oral aphthae, genital ulceration, skin lesions, and uveitis. Although it seems that the first description of this disease was made by Hippocrates in the 5^th century BC, the Turkish dermatologist Hulusi Behçet in 1937 proposed the association of oral and genital ulcers and uveitis as an expression of a distinct disease. This review aimed to critically examine the first descriptions by Hulusi Behçet and compare the clinical ocular findings he reported between 1937 and 1940 with those observed in the current era. No significant changes have been observed over time regarding gender distribution, mean age at onset, bilaterality, and occurrence of posterior/panuveitis, while the occurrence of hypopyon seems to decrease and that of anterior uveitis to increase. In Behçet's works, it is possible to find a quite a detailed description of many of the common clinical features of this disease, based on the observation of a few cases, and without the aid of modern ancillary technologies. Finally, in recent reports, there is no adequate acknowledgment of Behçet's first observations.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"41-46"},"PeriodicalIF":0.6,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behçet syndrome with eye involvement.","authors":"Didar Ucar, Sinem N Esatoglu","doi":"10.4103/sjopt.sjopt_228_24","DOIUrl":"10.4103/sjopt.sjopt_228_24","url":null,"abstract":"<p><p>Behçet's uveitis (BU) is a significant form of major organ involvement in Behçet syndrome and is associated with considerable morbidity. Ocular examination is crucial for diagnosing BS and detecting vitreous cells, even in asymptomatic patients. The primary goals in managing BU are to rapidly suppress ocular inflammation and prevent relapses. Initial treatment for posterior segment involvement in BU typically involves immunosuppressive agents combined with glucocorticoids. Biologic agents are increasingly used in BU management, including as first-line treatments for patients with poor prognostic risk factors or sight-threatening uveitis. There is no established consensus on when to discontinue or taper immunosuppressive therapy. Once remission is achieved, the absence of retinal vasculitis should be confirmed with fluorescein angiography, which should be utilized throughout the process of tapering immunosuppressive therapy. In addition to monoclonal tumor necrosis factor-alpha antagonists and tocilizumab, Janus kinase inhibitors may offer the potential for managing BU in the future.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"47-53"},"PeriodicalIF":0.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and mean platelet volume levels in pediatric keratoconus patients.","authors":"Mahmood D Al-Mendalawi","doi":"10.4103/sjopt.sjopt_301_24","DOIUrl":"10.4103/sjopt.sjopt_301_24","url":null,"abstract":"","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 1","pages":"112"},"PeriodicalIF":0.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}