Saudi Journal of Ophthalmology最新文献

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Five-year analysis: Outcomes and complications following neodymium: yttrium-aluminum-garnet laser posterior capsulotomy. 五年分析:钕钇铝石榴石激光后囊切开术的结果和并发症。
IF 1.1
Saudi Journal of Ophthalmology Pub Date : 2025-09-29 eCollection Date: 2026-07-01 DOI: 10.4103/sjopt.sjopt_12_25
Nicholas R Stange, Cameron E Paladino, Sean L Edelstein
{"title":"Five-year analysis: Outcomes and complications following neodymium: yttrium-aluminum-garnet laser posterior capsulotomy.","authors":"Nicholas R Stange, Cameron E Paladino, Sean L Edelstein","doi":"10.4103/sjopt.sjopt_12_25","DOIUrl":"10.4103/sjopt.sjopt_12_25","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the incidence of complications after neodymium: yttrium-aluminum-garnet (Nd:YAG) laser capsulotomy and propose follow-up based on individual risk factors.</p><p><strong>Methods: </strong>We conducted a retrospective review of Nd:YAG posterior capsulotomies performed at an academic center from April 2018 to March 2023. Exclusion criteria included anterior, surgical, and repeat capsulotomies. Parameters considered included intraocular pressure (IOP), corrected distance visual acuity, follow-up interval, and use of steroid or IOP-lowering eye drops. Complications within 1 year were analyzed to determine predisposing risk factors and laser parameters used.</p><p><strong>Results: </strong>Of 594 eyes, an adverse event occurred in 43 (7.2%) eyes, including ocular hypertension in 20 (3.4%), iritis in 7 (1.2%), cystoid macular edema in 6 (1%), corneal decompensation in 4 (0.7%), posterior vitreous detachment in 4 (0.7%), and retinal tear or detachment in 3 (0.5%). Of eyes with complications, 38 (88%) had predisposing risk factors. Eyes experiencing complications were more likely to have a 1-week follow-up (<i>P</i> < 0.00005), higher number of Nd:YAG laser spots (<i>P</i> < 0.05), increased power setting (<i>P</i> < 0.05), and greater total power delivered (<i>P</i> < 0.005). No correlation was noted related to use of anti-inflammatory eye drops following laser (<i>P</i> = 0.63).</p><p><strong>Conclusion: </strong>Although Nd:YAG laser capsulotomy is generally safe and effective, adverse events disproportionately affected those with risk factors. In low-risk eyes, routine corticosteroid use and early follow-up may be unnecessary.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"40 3","pages":"299-304"},"PeriodicalIF":1.1,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13585354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasound biomicroscopy findings in children eyes with nonacquired anomalies of lens shape and/or position. 儿童非获得性晶状体形状和/或位置异常的超声生物显微镜检查结果。
IF 1.1
Saudi Journal of Ophthalmology Pub Date : 2025-09-29 eCollection Date: 2026-07-01 DOI: 10.4103/sjopt.sjopt_291_24
Mohamed Shafik Shaheen, Nihal M El Shakankiry, Nader Bayoumi, Nada A El Din Khalifa
{"title":"Ultrasound biomicroscopy findings in children eyes with nonacquired anomalies of lens shape and/or position.","authors":"Mohamed Shafik Shaheen, Nihal M El Shakankiry, Nader Bayoumi, Nada A El Din Khalifa","doi":"10.4103/sjopt.sjopt_291_24","DOIUrl":"10.4103/sjopt.sjopt_291_24","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to report on biometric characteristics of anterior segments of children eyes suffering nonacquired abnormalities in lens shape and position.</p><p><strong>Methods: </strong>This case-control study was conducted on children presenting to the ophthalmology outpatient service of Alexandria Main University Hospital from September 2022 to March 2023 with developmental abnormalities in lens shape and/or position and age-matched control children presenting with congenital cataract. An initial office examination was followed by an examination under anesthesia for full clinical examination and ultrasound biomicroscopy (UBM).</p><p><strong>Results: </strong>The study included 57 eyes of 30 children and 51 eyes of 34 age-matched control children. The mean ± standard deviation age of study and control children was 68.4 ± 48.0 and 51.6 ± 22.6 months, respectively (<i>P</i> = 0.0845). Study eyes had statistically significantly larger corneal diameters (CDs), axial length, and cup/disc ratios and flatter (and thinner) corneas than control eyes. The most common lens abnormality was ectopia lentis (54.4%) followed by microspherophakia (31.6%). The UBM data revealed that study eyes had significantly shallower anterior chamber (AC), narrower anterior chamber angle (ACA), thicker and smaller natural crystalline lenses, narrower native (nonpharmacologically dilated) pupils, and larger sulcus-to-sulcus distances. Eyes with microspherophakia had significantly higher intraocular pressures, larger CDs, and shallower ACs than eyes with ectopia lentis. The mean lens decentration in horizontal and vertical directions was 1.6 ± 1.1 and 1.5 ± 1.2 mm, respectively, in eyes with ectopia lentis.</p><p><strong>Conclusion: </strong>The most prevalent nonacquired lens abnormalities are ectopia lentis and microspherophakia. Eyes with non-acquired abnormalities of lens shape and position have larger globes and flatter, thinner corneas than children eyes with congenital cataract.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"40 3","pages":"257-262"},"PeriodicalIF":1.1,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13585348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors contributing to spectacle intolerance: Insights from a multicenter study in Saudi Arabia. 导致眼镜不耐受的因素:来自沙特阿拉伯多中心研究的见解。
IF 1.1
Saudi Journal of Ophthalmology Pub Date : 2025-09-29 eCollection Date: 2026-07-01 DOI: 10.4103/sjopt.sjopt_349_24
Abdelaziz M Elmadina, Saleh Alshammeri, Saif H Alrasheed, Majid A Moafa, Raghda F Mutwaly, Naveen K Challa, Bandar M Alenezi, Mohammed M Alnawmasi, Hanan A Alkozi
{"title":"Factors contributing to spectacle intolerance: Insights from a multicenter study in Saudi Arabia.","authors":"Abdelaziz M Elmadina, Saleh Alshammeri, Saif H Alrasheed, Majid A Moafa, Raghda F Mutwaly, Naveen K Challa, Bandar M Alenezi, Mohammed M Alnawmasi, Hanan A Alkozi","doi":"10.4103/sjopt.sjopt_349_24","DOIUrl":"10.4103/sjopt.sjopt_349_24","url":null,"abstract":"<p><strong>Purpose: </strong>Spectacles are a popular method for correcting refractive errors and provide optimal visual acuity for most wearers. However, spectacle intolerance remains a significant challenge in vision correction. The aim of this study is to identify the common causes of spectacle intolerance in Saudi wearers.</p><p><strong>Methods: </strong>This cross-sectional, multi-optical center study was conducted across various regions of Saudi Arabia between August 2023 and April 2024. It included spectacle wearers aged 3-80 years who returned their new spectacles due to intolerance or discomfort. Spectacle prescriptions were compared to the dispensed lenses, and any discrepancies were corrected. Refraction was rechecked when necessary.</p><p><strong>Results: </strong>The prevalence of spectacle intolerance was 3% of 101 participants who did not tolerate or found their new spectacles uncomfortable, with a mean age of 33.4 ± 15.3 years. The most common reasons for spectacle intolerances were incorrect prescription (38.6%), decentered lenses (21%), adaptation difficulties (20.8%), improper fitting of lenses compared to the prescribed ones (9.9%), and nonprescription-related issues: misunderstanding use of spectacle, antireflection coatings, frame fashion, material, tint problem, and hard coating (3%-15.9%). The most predominant refractive prescription was myopic astigmatism (44%), presbyopia (24%), and myopia (16%).</p><p><strong>Conclusion: </strong>The prevalence of spectacle intolerance in Saudi Arabia was 3%. The study found that myopic astigmatism, presbyopia, and myopia were the most frequently spectacle intolerances. The main reasons for spectacle intolerances were incorrect prescription, decentered lenses, adaptation difficulties, and improper fitting of lenses. Age and gender had no effect on spectacle intolerance.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"40 3","pages":"263-267"},"PeriodicalIF":1.1,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13585347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of optical coherence tomography findings according to treatment response in patients with amblyopia. 根据治疗反应评价弱视患者的光学相干断层扫描结果。
IF 1.1
Saudi Journal of Ophthalmology Pub Date : 2025-09-29 eCollection Date: 2026-07-01 DOI: 10.4103/sjopt.sjopt_330_24
Pinar Orenc, Utku Demir, Saliha E Sonmezay, Hulya Gungel
{"title":"Evaluation of optical coherence tomography findings according to treatment response in patients with amblyopia.","authors":"Pinar Orenc, Utku Demir, Saliha E Sonmezay, Hulya Gungel","doi":"10.4103/sjopt.sjopt_330_24","DOIUrl":"10.4103/sjopt.sjopt_330_24","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate whether there is a difference in optical coherence tomography (OCT) parameters between patients who respond to treatment for amblyopia, patients who do not respond to treatment, and children who do not have amblyopia.</p><p><strong>Methods: </strong>Children were divided into three groups: those with full visual acuity after amblyopia treatment, Group 1; those without complete visual acuity, Group 2; and those without amblyopia, Group 3. Macular thickness (MT), retinal nerve fiber layer (RNFL), ganglion cell complex (GCC), and choroidal vascular index (CVI) parameters were measured by OCT and compared among the three groups.</p><p><strong>Results: </strong>A total of 110 eyes of 55 patients with amblyopia and 37 eyes of 37 healthy children were included in the study. There was no difference between the three groups in the mean central MT, RNFL, GCC, and CVI. A difference in macular inner temporal value was detected between Group 1 and 2 amblyopic eyes and the control group. There was a statistically significant difference between the 3 groups in the RNFL Superior and RNFL SN. However, there was no statistically significant difference between Group 1 and Group 2 in the 9-region MT or 12-region RNFL.</p><p><strong>Conclusion: </strong>Although there was a difference in the macular inner temporal, RNFL SUP, and RNFL SN parameters when the control group and children who received amblyopia treatment were compared, there was no difference in OCT parameters in treatment responder and nonresponder children after amblyopia treatment. OCT parameters do not provide additional information about the response to treatment for amblyopia.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"40 3","pages":"286-292"},"PeriodicalIF":1.1,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13585349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive evaluation of oculus pentacam in subclinical keratoconus and clinical keratoconus patients at different stages. pentacam对亚临床圆锥角膜患者和临床圆锥角膜患者不同阶段疗效的综合评价。
IF 1.1
Saudi Journal of Ophthalmology Pub Date : 2025-09-29 eCollection Date: 2026-01-01 DOI: 10.4103/sjopt.sjopt_261_24
Norsyariza Razak, Bariah M Ali, Wan H W A Halim
{"title":"Comprehensive evaluation of oculus pentacam in subclinical keratoconus and clinical keratoconus patients at different stages.","authors":"Norsyariza Razak, Bariah M Ali, Wan H W A Halim","doi":"10.4103/sjopt.sjopt_261_24","DOIUrl":"10.4103/sjopt.sjopt_261_24","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate and identify the ability of the Oculus Pentacam parameters to distinguish subclinical keratoconus (SCKC) and clinical keratoconus (CKC) at different stages in normal eyes.</p><p><strong>Methods: </strong>SCKC (<i>n</i> = 28), KC Stage I (<i>n</i> = 25), KC Stage II (<i>n</i> = 40), KC Stage III (<i>n</i> = 35), KC Stage IV (<i>n</i> = 26), and normal eyes (<i>n</i> = 46) were analyzed using the Oculus Pentacam HR. Comparisons between groups were assessed using Kruskal-Wallis and pairwise comparison Dunn tests. Receiver operating characteristic curves were used to determine the predictive accuracy of each parameter, as described by the area under the curve (AUC). The AUCs were compared using the DeLong method.</p><p><strong>Results: </strong>The SCKC group demonstrated a notable decrease in corneal thickness compared with the normal group. Index Surface Variance (ISV) had the highest ability to distinguish SCKC from normal (AUC: 0.897, sensitivity: 78.57%, specificity: 95.74%), followed by Ambrósio-Relational Thickness (ARTmax). ISV and index vertical asymmetry showed perfect discrimination ability to distinguish KC Stage I from normal eyes. Most of the Pentacam parameters had sufficient strength to differentiate between Stage II and normal eyes.</p><p><strong>Conclusion: </strong>The ISV from Pentacam was the most sensitive parameter for detecting SCKC, Stage I KC, and Stage II KC. Pentacam indices related to corneal thickness may be particularly valuable for identifying early signs of corneal ectasia when no abnormalities in topography are observed.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"40 1","pages":"1-9"},"PeriodicalIF":1.1,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distinct management of peripheral hypertrophic subepithelial corneal degeneration. 周围性增生性角膜上皮下变性的独特治疗方法。
IF 1.1
Saudi Journal of Ophthalmology Pub Date : 2025-08-08 eCollection Date: 2026-01-01 DOI: 10.4103/sjopt.sjopt_27_25
Abdullah Alfawaz, Hind M Alkatan, Khalid Almousa, Mona Alomairini
{"title":"Distinct management of peripheral hypertrophic subepithelial corneal degeneration.","authors":"Abdullah Alfawaz, Hind M Alkatan, Khalid Almousa, Mona Alomairini","doi":"10.4103/sjopt.sjopt_27_25","DOIUrl":"10.4103/sjopt.sjopt_27_25","url":null,"abstract":"<p><p>We report an atypical case of peripheral hypertrophic subepithelial corneal degeneration (PHSCD) managed with superficial keratectomy after 8 years of conservative treatment failure. A 34-year-old female presented with chronic bilateral foreign-body sensation, photophobia, and peripheral corneal opacities. The lesion was not extending to the visual axis or affecting visual acuity, unlike all the described cases in the literature. Initial management included lubricating drops and topical anti-inflammatory therapy, which failed to alleviate symptoms or stabilize the lesions. Slit-lamp and optical coherence tomography imaging revealed bilateral inferior peripheral subepithelial fibrosis without neovascularization. Superficial keratectomy was performed on the right eye to address her concerns about appearance and symptom persistence. Histopathology confirmed the diagnosis of PHSCD. Postoperative examination showed significant improvement in corneal appearance, peripheral thickness, and symptom relief with no recurrence at 2 months. The patient was scheduled for similar surgical management for the other eye. PHSCD is a rare, underreported corneal degeneration that may present with persistent symptoms unresponsive to medical management. Superficial keratectomy is an effective surgical option to restore corneal clarity and alleviate symptoms in advanced case. Further studies are needed to explore the disease's etiology, risk factors, and long-term surgical outcomes.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"40 1","pages":"95-98"},"PeriodicalIF":1.1,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlations of CO, SO2, PM10, NO2, and O3 with dry eye disease in Saudi Arabia. CO、SO2、PM10、NO2和O3与沙特阿拉伯干眼病的相关性
IF 1.1
Saudi Journal of Ophthalmology Pub Date : 2025-07-23 eCollection Date: 2026-07-01 DOI: 10.4103/sjopt.sjopt_286_24
Amani Y Alhalwani, Ismail I Fasfous, Mohamed E Ahmed, Abdulaziz J Raggam, Maan F Alsharif, Mohammad S Alghamdi, Yumna A Bokhari, Hashem Almarzouki, Urszula Deneka
{"title":"Correlations of CO, SO<sub>2</sub>, PM<sub>10</sub>, NO<sub>2</sub>, and O<sub>3</sub> with dry eye disease in Saudi Arabia.","authors":"Amani Y Alhalwani, Ismail I Fasfous, Mohamed E Ahmed, Abdulaziz J Raggam, Maan F Alsharif, Mohammad S Alghamdi, Yumna A Bokhari, Hashem Almarzouki, Urszula Deneka","doi":"10.4103/sjopt.sjopt_286_24","DOIUrl":"10.4103/sjopt.sjopt_286_24","url":null,"abstract":"<p><strong>Purpose: </strong>Dry eye disease (DED) is a multifactorial disease and has become a significant public health issue due to rapid urbanization and industrialization. This study aims to explore the association between air pollutant levels and DED in King Abdulaziz Medical City, Jeddah , Saudi Arabia.</p><p><strong>Methods: </strong>A total number of 492 patients were diagnosed with DED between January 1, 2017, and December 31, 2018. During the same study period, the Saudi Arabian General Authority of Meteorology and Environment Protection collected daily air data from three environmental monitoring stations in Jeddah measuring particulate matter (PM<sub>10</sub>), sulfur dioxide (SO<sub>2</sub>), nitrogen dioxide (NO<sub>2</sub>), ozone (O<sub>3</sub>), and carbon monoxide (CO).</p><p><strong>Results: </strong>Significant variation was reported for O<sub>3</sub>, SO<sub>2</sub>, and CO across the three monitoring stations. Multivariate regression analysis indicated SO<sub>2</sub> and CO were significantly correlated with diagnosed cases of DED (odds ratios [ORs]). According to adjusted OR, a one-unit rise in SO<sub>2</sub> (OR 1.182, 95% confidence interval [CI] 0.908-1.111, <i>P</i> = 0.021) was related to an 18% increase in diagnosed cases of DED in the western region, while the one-unit rise in CO (OR: 1.162, 95% CI 1.022-2.354, <i>P</i> = 0.041) was related to a 16% increase of diagnosed cases in the southern region.</p><p><strong>Conclusion: </strong>The prevalence of DED was highest in women and the elderly, mainly during the summer months (May-July). Correlations of air pollutants with DED indicated that SO<sub>2</sub> and CO levels were significantly correlated with DED, suggesting air pollutants are potential risk factors for DED. Controlling traffic emissions and industrial operations and adopting green commuting programs may contribute to lower occurrences of DED.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"40 3","pages":"248-256"},"PeriodicalIF":1.1,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13585344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is serum angiotensin-converting enzyme a suitable biomarker for differentiating idiopathic and demyelinating optic neuritis? 血清血管紧张素转换酶是鉴别特发性视神经炎和脱髓鞘性视神经炎的合适生物标志物吗?
IF 1.2
Saudi Journal of Ophthalmology Pub Date : 2025-07-23 eCollection Date: 2025-10-01 DOI: 10.4103/sjopt.sjopt_118_24
Alireza Dehghani, Nastaran-Sadat Hosseini, Majid Mirmohammadkhani, Matin Irajpour, Maryam Moayeri, Arman Amirkhani, Fatemeh Esfahanian, Mohsen Pourazizi
{"title":"Is serum angiotensin-converting enzyme a suitable biomarker for differentiating idiopathic and demyelinating optic neuritis?","authors":"Alireza Dehghani, Nastaran-Sadat Hosseini, Majid Mirmohammadkhani, Matin Irajpour, Maryam Moayeri, Arman Amirkhani, Fatemeh Esfahanian, Mohsen Pourazizi","doi":"10.4103/sjopt.sjopt_118_24","DOIUrl":"10.4103/sjopt.sjopt_118_24","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the study was to measure serum angiotensin-converting enzyme (ACE) in patients diagnosed with idiopathic and demyelinating optic neuritis (ON) as well as heathy individuals and assess its viability as a biomarker.</p><p><strong>Methods: </strong>This clinical case-control study was conducted on patients diagnosed with acute ON as the case group and healthy controls aged between 18 and 50 years. Based on findings from systemic and neurological evaluation, the study group was divided into: Idiopathic ON and demyelinating ON (including multiple sclerosis [MS], neuromyelitis optica [NMO], and clinically isolated syndrome [CIS]) subgroups. Serum ACE levels were measured using enzyme-linked immunosorbent assay and compared between groups.</p><p><strong>Results: </strong>Fifty-one patients with acute ON (78.4% female, mean age 29.8 ± 8.4 years) and 51 controls (78.4% female, mean age 29.9 ± 6.9 years) were enrolled in this study. In the case group, 29 patients were diagnosed with idiopathic ON (56.9%), and 22 patients with demyelinating types of ON (43.1%) (MS-ON, <i>n</i> = 16; NMO-ON, <i>n</i> = 3; and CIS, <i>n</i> = 3). The median serum ACE levels were 33.50 U/L (range: 29.40-46.20), and 34.25 U/L (range: 29.30-46.10) for patients diagnosed with idiopathic ON and demyelinating ON, respectively (<i>P</i> > 0.99). The mean serum ACE level for healthy individuals was 26.2 U/L (range: 24.80-20.50), and compared to other groups, it was significantly different (<i>P</i> < 0.001). Abnormal levels of serum ACE (defined as a serum ACE >65 U/L) were measured in 3 (10.3%) patients with idiopathic ON and 2 (9.1%) patients with the demyelinating ON (<i>P</i> > 0.99).</p><p><strong>Conclusion: </strong>Our findings did not exhibit a significant difference in terms of serum ACE level between patients diagnosed with idiopathic ON and demyelinating ON. However, serum ACE level in both groups is significantly higher compared to healthy subjects.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 4","pages":"378-382"},"PeriodicalIF":1.2,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12685261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145716162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Levator-based versus frontalis-based surgeries for poor-function congenital ptosis: Systematic review and meta-analysis. 基于提肛肌和基于额肌的手术治疗功能不佳的先天性上睑下垂:系统回顾和荟萃分析。
IF 1.2
Saudi Journal of Ophthalmology Pub Date : 2025-07-23 eCollection Date: 2025-07-01 DOI: 10.4103/sjopt.sjopt_43_25
Nada K Abdelsattar, Taha Abd-ElSalam Ashraf Taha, Ziad A Fadl, Omar A Ibrahim, Menna T S Ali, Hossam K Farouk, Mostafa M Diab
{"title":"Levator-based versus frontalis-based surgeries for poor-function congenital ptosis: Systematic review and meta-analysis.","authors":"Nada K Abdelsattar, Taha Abd-ElSalam Ashraf Taha, Ziad A Fadl, Omar A Ibrahim, Menna T S Ali, Hossam K Farouk, Mostafa M Diab","doi":"10.4103/sjopt.sjopt_43_25","DOIUrl":"10.4103/sjopt.sjopt_43_25","url":null,"abstract":"<p><p>The choice of surgery for congenital ptosis remains an ongoing debate. This study evaluated the efficacy and safety of levator-based versus frontalis-based surgeries, specifically focusing on ptosis with poor levator function. A comprehensive literature search was conducted across PubMed, Scopus, Web of Science, and the Cochrane Library. Studies comparing levator-based and frontalis-based surgical techniques in congenital ptosis patients were included. Sixteen studies were included. Meta-analysis revealed no significant differences regarding postoperative marginal reflex distance 1 (MRD1) or change in MRD1 in poor levator function cases and overall pooled studies. Levator-based surgeries had lower risk of recurrence and implant- or suture-related complications. Postoperative lagophthalmos was comparable between the two groups. In conclusion, both levator-based and frontalis-based surgeries achieve satisfactory outcomes for congenital ptosis, including cases with poor levator function. Large, randomized trials with long-term follow-up are needed.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"39 3","pages":"246-255"},"PeriodicalIF":1.2,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12578425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145432653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research productivity of ophthalmology residents in Saudi Arabia: A comprehensive analysis. 沙特阿拉伯眼科居民的研究生产力:一项综合分析。
IF 1.1
Saudi Journal of Ophthalmology Pub Date : 2025-07-09 eCollection Date: 2026-01-01 DOI: 10.4103/sjopt.sjopt_52_25
Waleed K Alsarhani, Yahya Alyahya, Abeer A Alkhodier, Ahmed S Al Zomia, Raed Alnutaifi, Motazz A Alarfaj, Rahaf M Al Malawi, Hind M Alkatan
{"title":"Research productivity of ophthalmology residents in Saudi Arabia: A comprehensive analysis.","authors":"Waleed K Alsarhani, Yahya Alyahya, Abeer A Alkhodier, Ahmed S Al Zomia, Raed Alnutaifi, Motazz A Alarfaj, Rahaf M Al Malawi, Hind M Alkatan","doi":"10.4103/sjopt.sjopt_52_25","DOIUrl":"10.4103/sjopt.sjopt_52_25","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the study was to assess the research productivity of ophthalmology residents in Saudi Arabia and identify factors associated with significant research output.</p><p><strong>Methods: </strong>This is a cross-sectional study of ophthalmology training programs across Saudi Arabia from 2015 to 2019.</p><p><strong>Results: </strong>The study included 225 ophthalmology residents, with a mean number of publications of 3.25 ± 4.59 and an average h-index of 1.20 ± 1.38. Statistically significant differences were observed between training programs in the mean number of publications (<i>P</i> < 0.001), h-index (<i>P</i> < 0.001), and citations (<i>P</i> < 0.001). The programs with the highest mean publication counts were King Saud University (8.03 ± 8.00), King Khaled Eye Specialist Hospital (3.80 ± 3.87), and the Eastern program (3.07 ± 4.04). Residents pursuing subspecialty fellowships, particularly in oculoplastic surgery and cornea, exhibited higher research output. Furthermore, the mean number of publications (<i>P</i> < 0.001), citations (<i>P</i> < 0.001), and h-index (<i>P</i> < 0.001) were associated with attaining future academic positions. Pursuing fellowship was significantly linked to the number of publications (<i>P</i> = 0.009) and h-index (<i>P</i> = 0.012).</p><p><strong>Conclusion: </strong>This study underscores the variability in research productivity among ophthalmology residents and highlights the influence of training programs, fellowship ambitions, and academic aspirations on research output.</p>","PeriodicalId":46810,"journal":{"name":"Saudi Journal of Ophthalmology","volume":"40 1","pages":"37-41"},"PeriodicalIF":1.1,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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