Radiological Physics and Technology最新文献

{"title":"A comparative evaluation of commercial software programs for automatic segmentation in breast cancer radiotherapy planning.","authors":"Anri Minamitake, Ryuji Murakami, Yasuhiro Doi, Takahiro Watakabe, Masato Maruyama, Kosuke Morita, Natsuo Oya","doi":"10.1007/s12194-026-01040-2","DOIUrl":"10.1007/s12194-026-01040-2","url":null,"abstract":"<p><p>Commercial software tools for automatic segmentation have been adopted in breast cancer radiotherapy planning. In this study, we directly compared commercial software programs for single-atlas-based segmentation (SABS), multi-atlas-based segmentation (MABS), and deep-learning-based segmentation (DLBS) on the ipsilateral breast using Eclipse v16, RayStation 16, and syngo.via RT Image Suite VB80G, respectively. Thirty previously registered atlases were stratified into three equal groups based on the mean bilateral breast height. An additional 20 patients with breast cancer who underwent radiotherapy after breast-conserving surgery were included retrospectively. For MABS, a parameter-matched tertile dataset was selected for each of the 20 test cases. For SABS, three of the 30 atlases were registered, and one of the registered atlases was selected for each test case by considering both nipple position and breast height. Manual segmentation was independently performed by two radiation oncologists. The Dice similarity coefficient (DSC) was used to assess agreement between two observers and between manual and automatic segmentations. The Friedman test was used to compare the DSC values of the automatic methods. The median DSC for interobserver agreement was 0.92. Although DSC values obtained using SABS were significantly lower than those of the other methods, its computation time was the shortest among the automatic methods. Despite the requirement for atlas datasets, MABS exhibited DSC values comparable to those of DLBS, with median DSC values of approximately 0.9 obtained in both methods. Clinical implementation can be optimized according to individual institutional requirements by understanding the strengths and limitations of each method.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"684-691"},"PeriodicalIF":1.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147515796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A practical method for measuring rotation angles in partial-angle CT scan by using CTDI phantoms, metal rods, and a real-time dosimeter.","authors":"Hironori Otsubo, Tomonobu Haba, Yusei Nishihara, Masanao Kobayashi, Rei Ito, Yoshiki Sunada, Tomoya Ishida, Haruki Ibamoto, Shigeki Kobayashi","doi":"10.1007/s12194-026-01060-y","DOIUrl":"10.1007/s12194-026-01060-y","url":null,"abstract":"<p><p>Partial-angle computed tomography (CT), including CT fluoroscopy and C-arm cone-beam CT systems, plays an important role in image-guided interventions. In these systems, the X-ray tube rotation angle is a critical factor affecting the dose evaluation. However, scans are often performed with partial rotations of approximately 180°-240°, and reliable methods for measuring the actual rotation angle have not been established. In this study, we propose a method for measuring the rotation angle in partial-angle CT scans and improving dose evaluation accuracy by incorporating the measured angles into Monte Carlo simulations. Measurements were performed using CT fluoroscopy and angiography. A CT dose index phantom was placed on the patient table, and metal rods and a real-time dosimeter were inserted into the peripheral holes and center hole, respectively. The rotation angles were identified from the X-ray attenuation caused by the metal rods, and the dose profiles for a single scan were determined by combining measurements acquired with and without the rods. The measured rotation angles and dose profiles were incorporated into Monte Carlo simulations and then validated against measured values. The differences between the displayed and measured rotation angles were 3.4% for CT fluoroscopy and 8.1% for angiography. Compared with the conventional method, the maximum discrepancy in dose evaluation was reduced by 9.0% for CT fluoroscopy and 4.8% for angiography. The proposed method facilitates rotation angle quality assurance in partial-angle CT scans and contributes to appropriate dose management.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"817-829"},"PeriodicalIF":1.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing proton therapy for superficial lesions using patient-specific bolus and multi-leaf collimator.","authors":"Yushi Wakisaka, Yuki Tominaga, Xing Li, Caroline Bamberger, Jackeline Castro, Kuan Ling Chen, Malgorzata D'Souza, Robabeh Rahimi","doi":"10.1007/s12194-026-01025-1","DOIUrl":"10.1007/s12194-026-01025-1","url":null,"abstract":"<p><p>In scanning proton therapy for superficial tumors, offset range shifters (ORS) may degrade the lateral penumbra as the air gap increases. This study evaluated the dosimetric benefit of replacing ORS with 3D-printed patient-specific boluses (PSBs) and assessed the effectiveness of combining PSBs with multi-leaf collimators (MLCs). Head and breast phantoms were CT-scanned, and 4-cm-thick PSBs made of thermoplastic polyurethane (TPU) and silicone were fabricated. PSBs were modeled in the treatment planning system using measured water-equivalent thickness (WET). Virtual planning target volumes were defined in superficial layers. Treatment plans were generated with ORS or PSB, with and without MLC, at air gaps of 5–20 cm. Dose conformity was assessed using the conformity index at the 50% isodose level (CI50%) and penumbra width (distance from 80% to 20% dose). To validate dose calculations with PSBs, measured lateral dose distributions were compared with calculations using gamma analysis (3%/2 mm). With ORS, CI50% was 2.45 ± 0.08/2.57 ± 0.05 and penumbra was 15.6 ± 1.2 mm/15.1 ± 1.38 mm for head/breast cases, showing inferior conformity. PSBs achieved higher conformity regardless of air gap. When combined with MLCs, PSBs provided the best results (CI50% = 1.93 ± 0.03/2.04 ± 0.02; penumbra = 3.7 ± 0.4 mm/4.1 ± 0.1 mm). Gamma pass rates exceeded 95% in all cases, confirming agreement between measurement and calculation. PSBs improved dose conformity compared with ORSs in superficial proton therapy, and their combination with MLCs further enhanced treatment quality.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"563-572"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146221644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dose enhancement by gold, iron oxide, bismuth oxide, and platinum nanoparticles in radiotherapy: a comprehensive meta-analysis.","authors":"Reza Malekzadeh, Shima Gholami, Mahboobeh Mehrabifard, Emad Khoshdel, Bahman Alipour, Naser Shifteh, Behnaz Babaye Abdollahi, Ali Reza Farajollahi","doi":"10.1007/s12194-026-01009-1","DOIUrl":"10.1007/s12194-026-01009-1","url":null,"abstract":"<p><p>This first global comprehensive meta-analysis of 64 studies compares four metal (gold (Au), iron oxide (IO), bismuth oxide (BO), platinum (Pt)) nanoparticles (NPs) as cancer radiosensitizers. Following PRISMA guidelines, we searched PubMed/Medline, Scopus, Web of Science, and Cochrane Library through November 2025 for studies on four metal NPS as cancer radiosensitizers. Meta-analysis calculated pooled dose enhancement factor (DEF) with comprehensive publication bias assessment (Egger’s, Begg’s, Trim-and-Fill, Fail-Safe N) and sensitivity analyses. Subgroup analyses examined nanoparticle size (≤ 10 nm, 10–30 nm, > 30 nm), radiation energy (≤ 100 keV, 100–250 keV, > 250 keV), and cancer cell line effects. Meta-regression evaluated size as a continuous predictor. Analysis of 95 independent data comparing four NPs revealed BO as most efficacious (0.575; 95% CI: 0.352–0.798; p = 0.001), followed by Au (0.395; 95% CI: 0.317–0.474; p = 0.001) and IO (0.293; 95% CI: 0.153–0.433; p = 0.001). Pt showed highest point estimate (0.780; 95% CI: 0.306–1.255; p = 0.001) but critically fragile evidence (Fail-Safe N = 2). Smaller NPs (≤ 10 nm, 0.500; 95% CI: 0.300–0.700) demonstrated 60% greater efficacy than 10–30 nm particles (0.312; 95% CI: 0.180–0.430). Orthovoltage radiation (≤ 100 keV0.710; 95% CI: 0.410–1.150) produced 2-fold greater enhancement than megavoltage (> 250 keV, 0.350; 95% CI: 0.240–0.460). Sensitivity analysis confirmed no influential outliers, with bismuth showing exceptional robustness (± 6% variation). BO is the optimal radiosensitizer, demonstrating highest efficacy with unbiased evidence. Smaller NPs (≤ 10 nm) and orthovoltage radiotherapy protocols maximize radiosensitization enhancement.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"479-498"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146259331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishment of local diagnostic reference levels for planning CT in adult and pediatric radiotherapy patients in 18 Japanese university hospitals.","authors":"Hideki Obara, Kiyokazu Sato, Satoshi Abe, Hiroki Katayama, Takahiro Ushijima, Takuro Okumura, Yuki Yuasa, Yoshinobu Shimohigashi, Hironori Kojima, Taka-Aki Hirose, Mizuho Saito, Takashi Iimori, Masanobu Terui","doi":"10.1007/s12194-026-01033-1","DOIUrl":"10.1007/s12194-026-01033-1","url":null,"abstract":"<p><p>Planning computed tomography (CT) for radiotherapy is essential for accurate treatment delivery but also contributes to patient radiation exposure. Therefore, diagnostic reference levels (DRLs) are recommended to optimize imaging doses. However, national DRLs (NDRLs) for planning CT in Japan have only recently been introduced. The aim of this study was to establish local diagnostic reference levels (LDRLs) for planning CT scans at 18 Japanese university hospitals for both adult and pediatric anatomical patients. Data were retrospectively collected from 2008 to 2022 for six adult anatomical regions and three pediatric regions. CT dose indices (volume CT dose index [CTDIvol] and dose length product [DLP]) were analyzed, and the 50th and 75th percentiles were calculated as the achievable and reference levels, respectively. In adults, the 75th percentile CTDIvol values were 86, 34, 24, 26, 24, and 38 mGy for the head, head and neck, thorax, upper abdomen, pelvis, and female pelvis, respectively. These values are generally higher than DRLs in several other countries but comparable to Japan’s DRLs in 2025. For pediatric head scans, the CTDIvol ranged from 59 to 74 mGy (75th percentile) across the age groups. The corresponding DLP ranged from 1469 to 2175 mGy·cm. The 75th percentiles of the CTDIvol were 25 and 18 mGy for the upper abdomen and whole body, respectively. This is the first multicenter study in Japan to propose LDRLs for planning CT scans, including pediatric cases. These findings support national dose optimization initiatives and provide a foundation for the establishment of NDRLs for radiotherapy.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"651-665"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147311254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of planning target margins in head and neck cancer patients undergoing radiotherapy: a multicentric study in Bangladesh.","authors":"Jobairul Islam, Abu Kausar, Mohammad Ullah Shemanto, Ali Abbas, Mostafa A Sumon, A F M Kamal Uddin, Alessio G Morganti, Savino Cilla","doi":"10.1007/s12194-026-01027-z","DOIUrl":"10.1007/s12194-026-01027-z","url":null,"abstract":"&lt;p&gt;&lt;p&gt;In radiation therapy, the planning target volume (PTV) is a geometrical concept used to account for the variations of target position during treatment in terms of systematic (Σ) and random (σ) errors. It ensures that the prescribed radiation dose is delivered to the target with a high degree of confidence. We report the results of a multi-institutional study investigating PTV margin calculation for head-and-neck cancer patients across four radiotherapy departments in Bangladesh, considering the specific challenges and resource constraints of the local context. Forty patients from four different Institutions were enrolled in this multicentric prospective study. All patients underwent planning computed tomography (CT) simulation on supine position, using a head-shoulder thermoplastic mask for immobilization. Contrast-enhanced CT images were acquired with a 3–5 mm slice thickness. All institutions used their locally developed treatment planning technique and inverse planning objectives for intensity-modulated radiotherapy (IMRT) or volumetric modulated arc therapy (VMAT) optimization, together with their imaging protocols (electronic portal imaging device (EPID)-based megavolt (MV), EPID-based kilovolt (kV) or cone-beam CT imaging (CBCT)). For each patient, shifts in the lateral (LR), antero-posterior (AP) and supero-inferior (SI) directions were recorded for each daily fraction. PTV margins in each direction and three-dimensional isotropic margins (PTV3D) were calculated using the Stroom and the van Herk’s equations. The comparisons among institutions were performed using the non-parametric statistical Kruskal-Wallis test, followed by a Dunn’s test. Results were compared with those published in literature for head-and-neck cancer radiotherapy. 1400 setup images from CBCT or EPID were analysed. Using the van Herk recipe, in order to ensure ≥ 95% of tumor coverage in 90% of patients, the isotropic PTV3D were calculated as 7.1, 4.7, 8.0 and 7.4 mm for the institutions A, B, C and D, respectively. Institution B reported significant smaller values for all metrics (p &lt; 0.05) that was attributed to the use of a hybrid kV-CBCT in the set-up protocol of this Institution, not used in the other three Centers. A total of 16 studies were identified from the literature, providing a weighted mean PTV3D margin of 6.8 mm. This multicentric study represents a significant step forward in addressing the challenges of PTV margin calculation for HNC patients in a low- and middle-income country setting. The findings highlight substantial variability in systematic and random errors across institutions, emphasizing the critical importance of customizing PTV margins to reflect local practices, available resources, and technological constraints. The study also demonstrates that accurate image-guided radiation therapy (IGRT) protocols, can significantly reduce PTV margins, potentially minimizing toxicity without compromising treatment efficacy, highlighting the need to ","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"573-581"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147311232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthetic MRI and radiomics in multiple sclerosis: improving precision in diagnosis and prognosis.","authors":"Mohammad Mehdi Azizi, Korosh Saber, Rasool Azmoonfar, Daryoush Shahbazi-Gahrouei","doi":"10.1007/s12194-026-01046-w","DOIUrl":"10.1007/s12194-026-01046-w","url":null,"abstract":"<p><p>Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, neurodegeneration, and gliosis in the central nervous system (CNS). While conventional magnetic resonance imaging (MRI) is essential for diagnosing and monitoring MS, it often fails to detect subtle microstructural changes. Synthetic MRI (SyMRI) produces multiple contrast-weighted images from a single acquisition and has emerged as a valuable tool for detailed tissue analysis. Combining SyMRI with radiomics, a method for extracting high-dimensional, sub-visual features from images, holds promise for enhancing MS assessment. This review critically evaluates the potential of this integration to improve lesion characterization, uncover early biomarkers of disease progression, and provide a more quantitative framework for monitoring treatment response, thereby moving towards personalized management strategies.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"440-453"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147869531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep learning model for body weight estimation from computed tomography scout images incorporating sex and height.","authors":"Taichi Okabayashi, Kei Terazaki, Hajime Sagawa, Koji Itagaki, Akira Matsuda","doi":"10.1007/s12194-026-01028-y","DOIUrl":"10.1007/s12194-026-01028-y","url":null,"abstract":"<p><p>Accurate body weight measurement is essential for determining the appropriate dose of contrast agent in contrast-enhanced computed tomography (CT) examinations. However, in emergency medicine, obtaining accurate measurements is often challenging, which can lead to over- or underdosing of contrast medium. Therefore, we aimed to develop and evaluate a deep learning model that estimates body weight using chest-abdominal CT scout images, sex, and height. We retrospectively analyzed the data of 763 hospitalized patients whose CT examination dates matched their weight-measurement dates. This dataset included patients with arms positioned alongside the body and those with metallic implants, commonly encountered in emergency medicine. After performing five-fold cross-validation, a deep learning model based on transfer learning with VGG16 was constructed. The following four input combinations were evaluated: (1) scout images alone; (2) scout images with sex; (3) scout images with height; and (4) scout images with sex and height. The percentages of cases with differences between predicted and actual body weights within ± 5 kg were 84.3%, 90.2%, 92.8%, and 90.2% for inputs (1)-(4), respectively. The corresponding mean absolute percentage errors were 4.8%, 4.7%, 4.1%, and 4.0%, respectively. Our method provides a useful tool for estimating body weight in patients of unknown weight, with its accuracy appearing largely unaffected even when the patients had arms positioned alongside the body or possessed metallic implants. Moreover, incorporating sex and height into the scout images further improved the prediction accuracy.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"582-592"},"PeriodicalIF":1.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147285449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MRI-based cerebrospinal fluid volumetric indices for predicting tap test response in idiopathic normal pressure hydrocephalus.","authors":"Shinya Hasegawa, Daisuke Yoshimaru, Norio Hayashi, Shuhei Shibukawa, Mika Takagi, Hisayuki Murai","doi":"10.1007/s12194-026-01048-8","DOIUrl":"10.1007/s12194-026-01048-8","url":null,"abstract":"<p><p>Idiopathic normal pressure hydrocephalus (iNPH) is a potentially reversible disorder; however, predicting symptom-specific improvement after cerebrospinal fluid (CSF) tap testing remains challenging. This exploratory study investigated whether MRI-derived CSF compartment volumes are differentially associated with gait and cognitive responses after tap testing. In this retrospective observational study, 50 patients with clinically diagnosed iNPH underwent 3.0-T MRI with 3D T1WI prior to tap testing. Third ventricle and bilateral choroid plexus volumes were quantified using automated FreeSurfer segmentation. Gait was assessed using the Timed Up and Go (TUG) test (completion time and step count), and cognition was assessed using the Mini-Mental State Examination (MMSE). Multivariable logistic regression adjusted for age, sex, and total intracranial volume was performed with false discovery rate correction. Receiver operating characteristic (ROC) analysis with bootstrap internal validation was conducted to evaluate discriminatory performance. Larger third ventricle volume was significantly associated with a lower probability of TUG step response (odds ratio per 100 mm³ increase = 0.857, 95% CI 0.760-0.965; FDR-adjusted p = 0.022), whereas no association was observed with TUG time response. Third ventricle volume demonstrated good discriminatory performance in this cohort for identifying TUG step responders (AUC = 0.876, 95% CI 0.772-0.958). In contrast, choroid plexus volume was not significantly associated with MMSE response after correction and showed limited discriminatory ability (AUC = 0.651, 95% CI 0.472-0.805). These findings suggest that third ventricle volumetry may serve as an exploratory imaging-based reference for gait pattern improvement after tap testing; however, the proposed cutoff values remain exploratory.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"742-754"},"PeriodicalIF":1.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between a T-tube and a spiralflow-tube to improve the visualization ability of the subclavian artery in CT angiography from the neck to the aortic arch.","authors":"Junichi Nakagawa, Norimi Nishiyama, Takashi Hoshino, Shota Watanabe, Isao Yamaguchi, Takanori Masuda","doi":"10.1007/s12194-026-01054-w","DOIUrl":"10.1007/s12194-026-01054-w","url":null,"abstract":"<p><p>This study aimed to compare contrast media (CM) remaining in the right subclavian vein after saline flush using a conventional T-tube or a spiralflow-tube in computed tomography angiography (CTA) from the neck to the aortic arch and to evaluate the visualization ability of the right subclavian artery. A total of 71 patients who underwent CTA from the neck to the aortic arch at our institution were retrospectively included (38 in the spiralflow-tube group and 33 in the T-tube group). The volumes of CM were measured in the volume-rendered images of the right subclavian vein by setting the thresholds of 300, 500, and 1000 Hounsfield units (HU) on a three-dimensional workstation. Two reviewers evaluated the depiction of the vascular visualization of the right subclavian artery using a 5-point scale. Data are presented as median (interquartile range; Q1-Q3). The volumes of CM remaining in the right subclavian vein were significantly smaller with the spiralflow-tube group than the T-tube group at all thresholds [300 HU: 0.95 (0.33-2.08) mL vs. 3.02 (1.66-8.64) mL; 500 HU: 0.30 (0.09-0.88) mL vs. 1.60 (0.73-3.61) mL; 1000 HU: 0.07 (0.05-0.35) mL vs. 0.48 (0.18-1.28) mL; all p < 0.01]. The spiralflow-tube group showed significantly higher visualization scores for the right subclavian artery than the T-tube group [5 (4-5) vs. 4 (3-4), p < 0.01]. The saline flush using a spiralflow-tube in CTA from the neck to the aortic arch reduced CM in the right subclavian vein and improved the vascular visualization ability of the right subclavian artery.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":"755-762"},"PeriodicalIF":1.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147785179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}