Case Reports in Gastrointestinal Medicine最新文献

{"title":"Selective ARID1A Loss Restricted to the Undifferentiated Component of a Mismatch Repair-Deficient Gastric Carcinoma: A Case Report.","authors":"Rika Omote, Ryosuke Hamano, Shinya Otsuka, Takehiro Tanaka, Hiroyuki Yanai","doi":"10.1155/crgm/8863202","DOIUrl":"https://doi.org/10.1155/crgm/8863202","url":null,"abstract":"<p><p>Mismatch repair-deficient (dMMR) gastric carcinomas often harbor ARID1A alteration, but a sharply demarcated undifferentiated/rhabdoid component with selective ARID1A loss is uncommon and may create a diagnostic dilemma. An 80-year-old man underwent esophagogastroduodenoscopy for anemia, which revealed a circumferential Borrmann Type 3 lesion in the gastric body, and distal gastrectomy was performed. Histologically, the tumor was composed predominantly of undifferentiated carcinoma with focal rhabdoid features and a minute well-differentiated adenocarcinoma component, with an abrupt transition between the two. Immunohistochemistry showed loss of nuclear MLH1 and PMS2 in both components, whereas loss of ARID1A expression was confined to the undifferentiated component; SMARCB1 (INI1), SMARCA2 (BRM), and SMARCA4 (BRG1) were retained. EBER in situ hybridization was negative. Because gene-level testing, MSI testing, and MLH1 promoter methylation analysis were not performed, the molecular basis of the dMMR phenotype and ARID1A loss could not be determined. The restricted scope of molecular testing limits the ability to draw broad or generalizable conclusions and to fully establish clinicopathological correlations. The value of this report is, therefore, not mechanistic proof but recognition of a practical morphologic-immunophenotypic observation: When a gastric carcinoma shows a sharply demarcated shift from differentiated to undifferentiated/rhabdoid morphology, dMMR should be considered, and selective ARID1A loss in the undifferentiated component may be associated with dedifferentiation. These findings should be interpreted with caution as preliminary, hypothesis-generating observations that require validation in larger studies with more extensive molecular profiling.</p>","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"2026 ","pages":"8863202"},"PeriodicalIF":0.5,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13139762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metastatic Squamous Cell Carcinoma of the Cervix Presenting With Haematemesis and Duodenal Obstruction: A Case Report and Literature Review.","authors":"D L Moodley, A C Van Wyk, M Y Sungay, A A Abdelsalem, M S Gabriel","doi":"10.1155/crgm/4772159","DOIUrl":"https://doi.org/10.1155/crgm/4772159","url":null,"abstract":"<p><strong>Background: </strong>Metastatic spread of cervical squamous cell carcinoma (SCC) to the duodenum is exceedingly rare, with fewer than 25 cases reported in the literature. Such metastases can present with gastrointestinal symptoms, including upper gastrointestinal bleeding or gastric outlet obstruction (GOO).</p><p><strong>Case presentation: </strong>We report the case of a 58-year-old female with a history of Stage IIB cervical cancer in remission, who presented with haematemesis. Initially, this was ascribed to peptic ulcer disease but was later diagnosed as GOO due to a duodenal mass. Histology confirmed metastatic p16-positive SCC, in keeping with metastatic cervical cancer. The patient's malignant GOO was palliated successfully with the placement of a self-expanding metal stent (SEMS). She died 1 month after discharge.</p><p><strong>Conclusion: </strong>This case highlights an uncommon metastatic pattern of cervical cancer, as well as the diagnostic challenge it can represent. In patients with prior malignancy, a high index of suspicion should be maintained when they present with GOO, regardless of the time interval. It also demonstrates the role of enteral stenting as an effective palliative approach in malignant GOO.</p>","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"2026 ","pages":"4772159"},"PeriodicalIF":0.5,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13139898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare but Life-Threatening Complication of Direct Endoscopic Necrosectomy: Tension Pneumoperitoneum With Pneumothorax and Hypercapnia due to Walled-Off Necrosis Rupture.","authors":"Yasuo Otsuka, Kosuke Minaga, Akane Hara, Mamoru Takenaka, Chihoko Nobori, Takaaki Murase, Ippei Matsumoto, Masatoshi Kudo","doi":"10.1155/crgm/6599334","DOIUrl":"https://doi.org/10.1155/crgm/6599334","url":null,"abstract":"<p><p>Endoscopic ultrasonography (EUS)-guided drainage followed by direct endoscopic necrosectomy (DEN) is widely used as a minimally invasive treatment for walled-off necrosis (WON). While this approach is considered effective and safe, serious complications may occur. We report a case of carbon dioxide (CO₂)-related tension pneumoperitoneum accompanied by severe hypercapnia during DEN. A 65-year-old man with gallstone pancreatitis developed a large WON causing gastric outlet obstruction. He underwent EUS-guided transgastric drainage with placement of a lumen-apposing metal stent (LAMS), followed by planned DEN sessions under CO₂ insufflation with propofol sedation. During the second DEN session, the LAMS became dislodged, and subsequent DEN was continued after balloon dilation of the endosonographically created route. During the fourth DEN session, the patient experienced sudden oxygen desaturation. Imaging revealed extensive free air in the abdominal and thoracic cavities, and arterial blood gas analysis showed severe hypercapnia. Emergency exploratory laparotomy revealed disruption of the WON wall with communication into the abdominal cavity. Surgical necrosectomy and abdominal irrigation were performed. The patient recovered uneventfully. This case highlights a rare but potentially serious CO₂-related complication of DEN and underscores the need for meticulous control of intracavitary pressure and close respiratory monitoring during the procedure.</p>","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"2026 ","pages":"6599334"},"PeriodicalIF":0.5,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13128969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147821930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Approach to Recurrent Hepatic Hydatid Cyst Using EUS-Guided Aspiration and Ethanol Injection: A Case Report and Focused Literature Review.","authors":"Pouyan Ebrahimi, Amin Esmaeilnia Shirvani, Mohammad Golparvar Azizi, Hadie Razjouyan, Seyed Hassan Abedi","doi":"10.1155/crgm/5497218","DOIUrl":"https://doi.org/10.1155/crgm/5497218","url":null,"abstract":"<p><strong>Background: </strong>Hepatic hydatid disease, a manifestation of cystic echinococcosis caused by <i>Echinococcus granulosus</i>, remains endemic in many regions and poses a persistent therapeutic challenge. Although surgery is often employed for definitive management, recurrence, procedural risks, and anatomical constraints have led to growing interest in minimally invasive alternatives such as percutaneous aspiration and endoscopic interventions.</p><p><strong>Case presentation: </strong>We report a 52-year-old male with an incidentally detected hepatic hydatid cyst who initially underwent surgical cystectomy and cholecystectomy. Twenty-five days postoperatively, the patient developed new abdominal fullness, and repeat imaging revealed a cystic lesion in the left hepatic lobe measuring 13.4 × 9.9 cm, reported radiologically as recurrence. The patient underwent endoscopic ultrasound (EUS)-guided fine-needle aspiration and lavage of the cyst cavity with 20 mL of 96% ethanol. The procedure was well tolerated with no adverse events, and follow-up imaging at 6 months confirmed complete cyst resolution.</p><p><strong>Conclusion: </strong>This case demonstrates the technical feasibility and clinical safety of EUS-guided ethanol ablation as a minimally invasive alternative for recurrent hepatic hydatid cysts. It highlights the expanding therapeutic potential of EUS beyond conventional indications and supports further exploration of this technique in selected cases.</p>","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"2026 ","pages":"5497218"},"PeriodicalIF":0.5,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13122556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Staphylococcal Gangrenous Cholecystitis: A Case Report.","authors":"Anandu Mathews Anto, George Sarin Zacharia, Maria Jaquez Duran, Dmitry Lvovsky","doi":"10.1155/crgm/3341650","DOIUrl":"https://doi.org/10.1155/crgm/3341650","url":null,"abstract":"<p><p>Gangrenous cholecystitis is a severe and potentially fatal complication of acute cholecystitis, typically resulting from ischemic necrosis of the gallbladder wall secondary to sustained obstruction and inflammation. We present a rare case of methicillin-sensitive <i>Staphylococcus aureus</i>-associated gangrenous cholecystitis with bacteremia in an elderly female without identifiable risk factors for staphylococcal infection. The patient was treated with antibiotics and emergent percutaneous cholecystostomy. This case highlights the need to consider infrequent pathogens, such as <i>S. aureus</i>, in patients with severe cholecystitis, particularly when clinical deterioration persists despite standard empirical therapy. Early diagnosis and prompt multidisciplinary management remain the key to a favorable outcome in this medically complex patient.</p>","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"2026 ","pages":"3341650"},"PeriodicalIF":0.5,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13111987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Markedly Elevated CA 19-9 in ANA/ASMA-Negative IgG4-Related Autoimmune Hepatitis With Concomitant Pancreatitis: A Case Report.","authors":"Hunter Scott, Samuel Reiss","doi":"10.1155/crgm/3494971","DOIUrl":"https://doi.org/10.1155/crgm/3494971","url":null,"abstract":"<p><strong>Background: </strong>IgG4-related disease (IgG4-RD) can involve the liver and pancreas and may present without conventional autoimmune hepatitis (AIH) autoantibodies, creating diagnostic delay unless IgG4 testing and tissue immunostaining are pursued. We describe an older man with acute hepatocellular injury and marked hyperbilirubinemia who was negative for antinuclear (ANA) and antismooth muscle (ASMA) antibodies but had markedly elevated serum IgG4 and IgG4-positive plasma cell infiltration on liver biopsy, consistent with IgG4-related autoimmune hepatitis (IgG4-AIH).</p><p><strong>Case presentation: </strong>A man in his 80s presented with abdominal pain followed by progressive jaundice and pruritus, with acute hepatocellular injury and hyperbilirubinemia. Evaluation showed negative ANA and ASMA, elevated total IgG (2166 mg/dL) and IgG4 (442.5 mg/dL), CA 19-9 1268 U/mL, and CT/MRCP findings consistent with pancreatitis without biliary obstruction or mass. HFE analysis showed compound heterozygosity. Liver biopsy demonstrated interface hepatitis with plasma cell-rich inflammation and increased IgG4-positive plasma cells (up to 58 per high-power field), supporting IgG4-AIH. Minimal iron deposition on biopsy favored inflammation-related iron study abnormalities rather than primary hemochromatosis. The pancreatic findings were most consistent with probable Type 1 autoimmune pancreatitis. Prednisone 40 mg daily led to improvement, with normalization of transaminases and total bilirubin by Day 57 (approximately 8 weeks) in available follow-up testing.</p><p><strong>Conclusion: </strong>IgG4-AIH is diagnostically challenging, particularly in seronegative presentations. Unexpectedly high CA 19-9 may be seen in IgG4-RD, which may mimic malignancy. In atypical presentations such as those occurring in older adults without conventional antibody positivity or with concurrent pancreatitis on imaging, clinicians should promptly consider early biopsy with immunostaining to avoid diagnostic delay and enable timely steroid treatment.</p>","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"2026 ","pages":"3494971"},"PeriodicalIF":0.5,"publicationDate":"2026-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13092795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Varicella-Zoster Virus-Associated Esophagogastritis.","authors":"Masaya Iwamuro, Takehiro Tanaka, Motoyuki Otsuka","doi":"10.1155/crgm/9319708","DOIUrl":"10.1155/crgm/9319708","url":null,"abstract":"<p><p>Varicella-zoster virus (VZV) typically manifests as varicella or herpes zoster; however, in immunocompromised patients, viral reactivation may result in disseminated infection with visceral organ involvement. Gastrointestinal involvement is particularly rare and often underrecognized. We report a case of biopsy-proven VZV-associated esophagogastritis in a patient with Richter syndrome undergoing chemotherapy. A 77-year-old man was admitted with abdominal pain, anorexia, and fatigue. On hospital Day 3, he developed disseminated papulovesicular skin lesions. Cytologic examination of vesicular fluid revealed multinucleated giant cells, and antigen testing confirmed VZV infection. Esophagogastroduodenoscopy demonstrated erosions with white exudates in the esophagus and multiple gastric ulcers. Biopsy specimens from both the esophagus and stomach showed positive immunohistochemical staining for VZV. In addition, esophageal specimens exhibited characteristic viral cytopathic changes, including intranuclear inclusion bodies and multinucleation, confirming the diagnosis of VZV-associated esophagogastritis. Intravenous acyclovir therapy resulted in marked improvement of both cutaneous and gastrointestinal lesions. VZV-associated esophagogastritis is a rare but clinically significant manifestation of disseminated VZV infection. This condition should be considered in immunocompromised patients presenting with unexplained gastrointestinal symptoms, even before the appearance of characteristic skin lesions. Early endoscopic evaluation with biopsy and appropriate virological testing is essential for timely diagnosis and effective antiviral treatment.</p>","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"2026 ","pages":"9319708"},"PeriodicalIF":0.5,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13084138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unmasking a Rare Genetic Puzzle: Hereditary Hemorrhagic Telangiectasia in a Black Kenyan Woman: A Case Report.","authors":"Lavender Otom, Priyanka Panwar, Farida Kaittany, Ben Clement Lomatayo","doi":"10.1155/crgm/3692365","DOIUrl":"https://doi.org/10.1155/crgm/3692365","url":null,"abstract":"<p><strong>Background: </strong>Hereditary hemorrhagic telangiectasia (HHT) is a rare genetic disorder characterized by mucocutaneous and visceral telangiectasias, often leading to severe complications. This case report presents an uncommon manifestation of HHT in a 57-year-old Black Kenyan female with upper gastrointestinal bleeding. Given the rarity of HHT in our region, this case underscores the importance of early recognition, particularly in resource-limited settings, to improve patient outcomes.</p><p><strong>Case presentation: </strong>A 57-year-old Black Kenyan female presented with recurrent upper gastrointestinal bleeding. Endoscopy revealed multiple telangiectatic lesions in the stomach and duodenum, with an actively bleeding duodenal telangiectasia. Despite limited diagnostic resources, a thorough history and focused clinical examination led to the diagnosis of HHT. She was managed with blood transfusions, intravenous iron, tranexamic acid, and supportive therapy to control bleeding. Systemic therapy with low-dose tacrolimus was later initiated for recurrent gastrointestinal bleeding. This case illustrates the diagnostic and therapeutic challenges faced in a low-resource setting.</p><p><strong>Conclusion: </strong>This is the first documented case of HHT with upper gastrointestinal bleeding reported in Western Kenya. Raising awareness of this rare condition among healthcare providers can facilitate early diagnosis and intervention, ultimately improving patient outcomes.</p>","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"2026 ","pages":"3692365"},"PeriodicalIF":0.5,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12927944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147285656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Biliary Source <i>Klebsiella pneumoniae</i> Pyogenic Liver Abscess With Colon Adenocarcinoma: A Case Report.","authors":"Dongmin Shin, Sameer Kandhi, Franklin Sosa, George Zacharia, Harish Patel","doi":"10.1155/crgm/8835902","DOIUrl":"10.1155/crgm/8835902","url":null,"abstract":"<p><strong>Background: </strong>Pyogenic liver abscesses (PLAs) commonly result from hematogenous spread or biliary tract infections, most often due to cholecystitis or cholangitis. <i>Klebsiella pneumoniae</i> is a recognized pathogen in PLA and has been associated with underlying gastrointestinal malignancies, particularly colorectal cancer. While screening for malignancy is well established in cryptogenic <i>K. pneumoniae</i> liver abscess, its role when a clear biliary source is present is less well described.</p><p><strong>Case presentation: </strong>We report a 76-year-old man with a history of untreated hepatitis C and prior renal cell carcinoma who presented with right upper quadrant pain, weight loss, and leukocytosis. Imaging revealed a pericholecystic liver abscess with acute cholecystitis. The abscess was drained percutaneously, and cultures grew <i>K. pneumoniae</i>. Although imaging suggested a biliary source, colonoscopy was performed given the pathogen's known association with colorectal neoplasia. This revealed multiple large laterally spreading tumors, including a 30-mm ascending colon lesion confirmed as well-differentiated invasive adenocarcinoma on biopsy.</p><p><strong>Conclusion: </strong>This case underscores the importance of considering colorectal cancer screening in patients with <i>K. pneumoniae</i> PLA, even when a biliary source is identified. Early endoscopic evaluation in such patients may facilitate timely diagnosis of occult malignancy and alter clinical management.</p>","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"2026 ","pages":"8835902"},"PeriodicalIF":0.5,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12867004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146120297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Newly Diagnosed Crohn's Disease After SARS-CoV-2 Infection.","authors":"Hironori Yamada, Toru Yamada, Shuji Ouchi, Ryota Nakamura, Akiko Tamura, Iichiroh Onishi, Masayoshi Hashimoto","doi":"10.1155/crgm/2252518","DOIUrl":"10.1155/crgm/2252518","url":null,"abstract":"<p><p>Coronavirus disease 2019 (COVID-19) is known to induce gastrointestinal symptoms as well as respiratory symptoms. There have been instances where diarrhea persists after the acute phase of COVID-19, suggesting an extension of the disease's symptoms. It is not typical to recall the onset of inflammatory bowel disease (IBD) with such symptoms, much less with reports on Crohn's disease (CD). It is important to collect such cases in order to lead to appropriate diagnosis and treatment. This report presents a case of a young man in which diarrhea, initially manifesting during the acute phase of COVID-19, persisted for two months, ultimately leading to a CD diagnosis. At the onset of COVID-19, the patient had fever, abdominal pain, and diarrhea, but respiratory symptoms were not prominent. An ileocolonoscopy was performed to further investigate the cause of persistent diarrhea, leading to an appropriate diagnosis of CD. It is hypothesized that aberrations in the immune system triggered by severe acute respiratory syndrome coronavirus 2's impact on the intestinal tract might contribute to the onset of CD. The patient's condition gradually improved after the initiation of treatment with prednisolone. By the following treatment with azathioprine, the patient has maintained clinical remission. Clinicians should consider performing ileocolonoscopy for patients with persistent diarrhea after COVID-19, given the possibility of IBD. Gastrointestinal symptoms are relatively common with COVID-19. COVID-19 infection may trigger CD through immunological mechanisms. It is important to consider that cases of prolonged diarrhea after COVID-19 may include the induction of CD and to perform an ileocolonoscopy.</p>","PeriodicalId":45645,"journal":{"name":"Case Reports in Gastrointestinal Medicine","volume":"2026 ","pages":"2252518"},"PeriodicalIF":0.5,"publicationDate":"2026-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12860508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146107779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}