Martynas Maciulevičius , Reda Rulinskaitė , Lukas Giedrimas , Rūta Palepšienė , Paulius Ruzgys , Rytis Jurkonis , Mindaugas Tamošiūnas , Renaldas Raišutis , Kristine Saleniece , Saulius Šatkauskas
{"title":"Ca2+ sonotransfer into breast cancer cells in a suspension, 3-D spheroid and subcutaneous tumor models","authors":"Martynas Maciulevičius , Reda Rulinskaitė , Lukas Giedrimas , Rūta Palepšienė , Paulius Ruzgys , Rytis Jurkonis , Mindaugas Tamošiūnas , Renaldas Raišutis , Kristine Saleniece , Saulius Šatkauskas","doi":"10.1016/j.ultsonch.2025.107381","DOIUrl":"10.1016/j.ultsonch.2025.107381","url":null,"abstract":"<div><div>Calcium-based treatments have gained considerable attention in the field of electroporation, primarily, due to their comparable efficacy to conventional electro-chemotherapy. However, their applications in sonoporation remain under-investigated, despite its high potential for site-specific and temporally-controlled drug delivery.</div><div>Current study examines the curative potential of calcium sonoporation across multiple experimental models, including: i) cell suspension, ii) 3-D spheroid culture and iii) subcutaneous murine breast cancer tumors. Murine breast cancer is an established analogue of stage IV human breast cancer. For comparison, parallel experiments, using classical anticancer drug bleomycin were performed.</div><div>Ca<sup>2+</sup> sonoporation efficiently enhanced 4 T1 cell death in a suspension in the absence of microbubbles, under relatively low acoustic pressure (100–200 kPa). In contrast, efficient spheroid growth reduction required microbubble-mediated inertial cavitation at higher (700 kPa) acoustic pressure.</div><div><em>In vivo</em>, Ca<sup>2+</sup> sonoporation demonstrated similar tumor growth reduction as bleomycin sonoporation. Both treatments reduced tumor growth from the third day after the onset of treatment. Successful cancer treatment was achieved even at lower values of cavitation dose metrics.</div><div>Our study presents a multi-level validation of Ca<sup>2+</sup> sonoporation as an effective treatment strategy for murine breast cancer. Importantly, complete tumor eradication and prolonged animal survival up to one month were observed even at significantly reduced cavitation activity, indicating clinical safety of the treatment.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"118 ","pages":"Article 107381"},"PeriodicalIF":8.7,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143922067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ermelinda Falletta , Anna Donnadio , Nikoletta Mila , Niloofar Haghshenas , Vincenzo Fabbrizio , Riccardo Vivani , Alessia Giordana , Gabriele Perna , Francesco Cottone , Alessandro Di Michele , Claudia L. Bianchi
{"title":"Ultrasound-assisted synthesis of strontium-bismuth titanate and its application in environmental remediation","authors":"Ermelinda Falletta , Anna Donnadio , Nikoletta Mila , Niloofar Haghshenas , Vincenzo Fabbrizio , Riccardo Vivani , Alessia Giordana , Gabriele Perna , Francesco Cottone , Alessandro Di Michele , Claudia L. Bianchi","doi":"10.1016/j.ultsonch.2025.107380","DOIUrl":"10.1016/j.ultsonch.2025.107380","url":null,"abstract":"<div><div>The pollution of water and air in our world has become a global challenge that requires innovative and sustainable strategies. In this work, the ultrasound-assisted synthesis of bare strontium titanate (STO) and bismuth-doped STO (Bi-STO) is proposed to enhance the photocatalytic and piezocatalytic performance of STO in environmental remediation. The materials were fully characterized using various physicochemical techniques, such as XRD, XPS, BET, UV-DRS, PL, SEM, TEM, and piezoelectric measurements, to assess their structural, optical, morphological and piezoelectric properties. The results revealed that Bi-STO induced lattice distortion, reduced band gap energy, enhanced charge separation efficiency, and improved piezoelectricity respect STO.</div><div>The activity of the as-prepared materials was investigated in the field of wastewater remediation through three different approaches: photocatalysis, piezocatalysis, and piezo-photocatalysis, applied in the ibuprofen (IBU) degradation, as well as in the photocatalytic removal of volatile organic compounds (VOCs) and nitrogen oxides (NOx) under different irradiation conditions. The results demonstrated that Bi-STO exhibited superior catalytic performance respect STO, achieving up to 60% IBU degradation under piezo-photocatalysis, thanks to the synergy between light and ultrasound. Furthermore, Bi-STO enabled the complete removal of ethanol and NOx and more than 90% propionic acid reduction under UV irradiation.</div><div>This study demonstrates the potential of Bi-STO as an efficient catalyst for environmental remediation, offering an alternative to conventional materials. The present work opens new possibilities for optimizing and improving wastewater treatment and air purification.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"118 ","pages":"Article 107380"},"PeriodicalIF":8.7,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143929254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Efraím A. Serna-Galvis , Kevin P. Celis-Llamoca , Ingrit E. Collantes-Díaz , Ricardo A. Torres-Palma , Jessica I. Nieto-Juárez
{"title":"Insights into the transformations, antimicrobial activity, and degradation efficiency of a representative carbapenem antibiotic by high-frequency ultrasound hybridized with the (photo)Fenton process","authors":"Efraím A. Serna-Galvis , Kevin P. Celis-Llamoca , Ingrit E. Collantes-Díaz , Ricardo A. Torres-Palma , Jessica I. Nieto-Juárez","doi":"10.1016/j.ultsonch.2025.107379","DOIUrl":"10.1016/j.ultsonch.2025.107379","url":null,"abstract":"<div><div>Carbapenems are potent antibiotics that reach sewage systems and then the environment, causing negative impacts. Thus, research on degrading processes to limit the carbapenem discharge in sewage systems is needed. Herein, fundamental aspects of high-frequency ultrasound alone and hybridized with the (photo)Fenton process to deal with a representative carbapenem antibiotic (meropenem, MERO) in water were considered. Initially, the action of ultrasound alone (at 578 kHz) on MERO in distilled water was tested for degradation, resulting in a partial removal (∼53 % after 120 min) and a moderate pseudo-first-order-kinetics (<em>k</em>: 6.3 × 10<sup>−3</sup> min<sup>−1</sup>). Then, to enhance the MERO elimination ferrous ions were added to the ultrasound system, forming the sono-Fenton process. The increase in the ferrous ions concentration from 0 to 5 mg L<sup>−1</sup> augmented the rate of MERO degradation (<em>k</em> changed from 6.3 to 15.7 × 10<sup>−3</sup> min<sup>−1</sup>) and diminished the electric energy consumption from 1.22 to 0.49 kWh L<sup>−1</sup>. Afterward, the MERO treatment by the hybridized sono-photo-Fenton process (i.e., ultrasound combined with Fe<sup>2+</sup> and UVA light) was evaluated, showing that the degradation efficiency was higher than by the sono-Fenton or photolysis (indeed, a synergistic index of 1.11 was obtained). Moreover, the sono-photo-Fenton process decreased the antimicrobial activity (against <em>Staphylococcus aureus</em>) after 30 min of treatment, indicating that the by-products did not have antimicrobial activity. The structures of primary by-products, at 50 % of MERO degradation, were elucidated through Fukui indices and LC-MS, finding that the pyrroline ring, β-lactam core, and thioether group on MERO were susceptible to the attacks of generated hydroxyl radicals (HO<img>) and the primary transformations occurred on such moieties of the antibiotic. Finally, the treatment of MERO in synthetic hospital wastewater by the action of the sono-photo-Fenton process was assessed, degrading 36 % of MERO at 60 min of treatment. The results from this research indicated that the hybridized processes could be an alternative to be used in niche applications for treating carbapenem antibiotics even in complex matrices, transforming them into less problematic compounds.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"119 ","pages":"Article 107379"},"PeriodicalIF":8.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143942542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dileswar Pradhan , Swarna Jaiswal , Brijesh K. Tiwari , Amit K. Jaiswal
{"title":"Ultrasound-Assisted sequential processing of barley straw using binary acidic and hydrated ternary deep eutectic solvents for nanocellulose production","authors":"Dileswar Pradhan , Swarna Jaiswal , Brijesh K. Tiwari , Amit K. Jaiswal","doi":"10.1016/j.ultsonch.2025.107376","DOIUrl":"10.1016/j.ultsonch.2025.107376","url":null,"abstract":"<div><div>This study aimed to valorise barley straw by using a binary acidic deep eutectic solvent (DES) made from choline chloride and lactic acid for biomass pretreatment, and a hydrated ternary DES (HDES) composed of betaine, oxalic acid, and water (BOW HDES) for downstream processing to produce nanocellulose. The ultrasound-assisted DES pretreatment significantly enhanced lignin and hemicellulose solubilisation, achieving an average lignin removal of 70.54 % and hemicellulose solubilisation of 69.58 % under optimal conditions. Purification of US-DES-treated solid residue resulted in a cellulose yield of 39.81 ± 1.47 % with a purity of 91.31 ± 0.93 %, comparable to or exceeding conventional fractionation methods. The yield of lignin-rich material was 9.40 ± 0.89 % with a lignin purity of 83.29 ± 1.57 %. Further, nanocellulose was produced using a sequential process comprising low-viscosity HDES treatment, which improved fibre swelling and solubilisation, followed by high-intensity ultrasound (HIUS) treatment for nanoscale defibrillation. DLS analysis of the optimal nanocellulose sample revealed that 77.8 % of nanoparticles had a diameter below 100 nm, demonstrating a high yield of nanoscale material. XRD analysis confirmed the preservation of the cellulose I crystalline structure throughout processing, ensuring structural integrity. These findings demonstrate an efficient and sustainable biorefinery approach for lignin, cellulose, and nanocellulose extraction from agricultural residues, offering potential for scalable nanocellulose production.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"118 ","pages":"Article 107376"},"PeriodicalIF":8.7,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143906825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peyman Ebrahimi , Ali Roodbali , Barbara Simonato , Anna Lante , Corrado Rizzi
{"title":"Unveiling the effects of sieving and drying on ultrasound-assisted extraction of bioactive compounds from spent sour cherry pomace","authors":"Peyman Ebrahimi , Ali Roodbali , Barbara Simonato , Anna Lante , Corrado Rizzi","doi":"10.1016/j.ultsonch.2025.107375","DOIUrl":"10.1016/j.ultsonch.2025.107375","url":null,"abstract":"<div><div>Spent sour cherry pomace (SSCP), a by-product from Maraschino liqueur production, is a rich source of polyphenols worth valorizing. However, its high moisture content promotes microbial spoilage and reduces extraction efficiency per unit weight, limiting their valorization. This study evaluated the impacts of freeze-drying and oven-drying and different particle sizes (≤100, ≤200, and ≥ 200 µm) for efficient ultrasound-assisted recovery of polyphenols. The moisture content decreased by 83.33 % in freeze-drying and 84.17 % in oven-drying, resulting in a higher yield of bioactive compounds from a given sample weight. Smaller particle sizes significantly improved extraction efficiency, probably due to increased surface area. Freeze-dried samples at ≤ 100 µm had the highest total phenolic content (224.32 ± 3.13 mg gallic acid equivalent/L), total monomeric anthocyanin content (9.48 ± 0.12 mg/L), and ferric reducing antioxidant power (487 ± 3.58 mg Trolox equivalent/L), along with the highest levels of epicatechin (1.15 ± 0.11 mg/L) and cyanidin-3-rutinoside (9.81 ± 0.06 mg/L). These results suggest that freeze-drying preserves bioactive compounds better than oven-drying. SEM images from post-extraction SSCP pellets showed a generally identical cell disruption among all the samples, highlighting that the differences in the extract properties are highly dependent on the sample preparation method (<em>i.e.,</em> drying process), despite the key role of the extraction process. The antioxidant activity of the extracts from oven/freeze-dried SSCPs at ≤ 100 µm was evaluated in soybean and sunflower oils using the Rancimat method. The extract competency in delaying lipid oxidation in the oils showed their potential as natural antioxidants for future food applications.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"118 ","pages":"Article 107375"},"PeriodicalIF":8.7,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juyeon Han , Yongyeol Park , Ok Sung Jeon , Dongpyo Hong , Yuanzhe Piao , Young Joon Yoo , Sang Yoon Park , Se Hun Lee , Jeeyoung Yoo
{"title":"Ultrasonic synthesis of conducting polymers intercalated potassium vanadate nanofiber composites as cathode for aqueous zinc-ion batteries","authors":"Juyeon Han , Yongyeol Park , Ok Sung Jeon , Dongpyo Hong , Yuanzhe Piao , Young Joon Yoo , Sang Yoon Park , Se Hun Lee , Jeeyoung Yoo","doi":"10.1016/j.ultsonch.2025.107378","DOIUrl":"10.1016/j.ultsonch.2025.107378","url":null,"abstract":"<div><div>Aqueous zinc-ion batteries (AZIBs) have gained attention as next-generation energy storage systems due to their safety, cost-effectiveness, and eco-friendliness. However, their commercialization is hindered by the structural instability and low electrochemical performance of cathode materials. Herein, we present poly(3,4-ethylenedioxythiophene) (PEDOT)-intercalated potassium vanadate nanofibers (E-PVNF) with oxygen vacancies, synthesized via a sonochemical method. Oxygen vacancies play a crucial role in facilitating Zn<sup>2+</sup> diffusion and charge transport by providing additional ion migration channels and enhancing electronic conductivity. The E-PVNF exhibited a high specific capacity of 182.50mAh g<sup>−1</sup> even at a high current density of 15 A g<sup>−1</sup>, significantly outperforming conventional potassium vanadate-based cathodes. To investigate the electrochemical behavior, overpotential and Zn<sup>2+</sup> diffusion coefficient (<em>D<sub>Zn</sub><sup>2+</sup></em>) were systematically evaluated as a function of synthesis time. The results revealed a substantial reduction in overpotential and a notable increase in <em>D<sub>Zn</sub><sup>2+</sup></em>, reaching 3.86 × 10<sup>−10</sup> cm<sup>2</sup> s<sup>−1</sup>, nearly double that of pristine potassium vanadate. This improvement is attributed to the synergistic effects of PEDOT intercalation and oxygen vacancy engineering, which optimize Zn<sup>2+</sup> diffusion pathways and enhance charge transfer. Additionally, while oxygen vacancies facilitate ion and electron transport, they do not directly increase theoretical capacity. This study provides a scalable and effective electrode design strategy for high-performance AZIBs, offering insights into the role of conducting polymer intercalation and oxygen vacancy engineering in improving electrochemical stability and rate capability.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"118 ","pages":"Article 107378"},"PeriodicalIF":8.7,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143935787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liye Cui , Hengxun Lin , Xiaojia Hu , Wenqiang Guan , Xia Li , Wei Jia , Yiping Yang , Yong Chen , Chunhui Zhang
{"title":"Ultrasound-assisted immersion freezing method as a new strategy to improve the quality and microstructure of Chinese beef stewed dishes","authors":"Liye Cui , Hengxun Lin , Xiaojia Hu , Wenqiang Guan , Xia Li , Wei Jia , Yiping Yang , Yong Chen , Chunhui Zhang","doi":"10.1016/j.ultsonch.2025.107373","DOIUrl":"10.1016/j.ultsonch.2025.107373","url":null,"abstract":"<div><div>Prepared dishes, as a technological extension of pre-conditioned foods and representative products of the central kitchen, are becoming a major part of people’s daily diets. However, the problem of dish quality deterioration owing to freezing in the frozen supply chain has not yet been addressed, and freezing quality enhancement techniques are lacking. Herein, special equipment was used to investigate effects of ultrasound-assisted immersion freezing (UIF) on the quality of the prepared dish (braised beef with potato) and compare it with immersion freezing (IF) and conventional air freezing (AF). Results indicated that UIF effectively shortened the freezing time and improved the freezing rate of the dish. A suitable intensity of UIF treatment (150 W) improved dish quality, and high-intensity UIF treatments (300 and 450 W) caused tissue structure destruction and decreased quality. The hardness of beef and potatoes treated with UIF-150 was significantly higher than that of other treatments (<em>P</em> < 0.05). Scanning electron microscopy demonstrated that UIF-150 reduced the size of ice crystals and maintained the structural integrity of beef and potatoes. Porosity values of beef were 6.91 %, 2.66 %, 2.09 %, 4.30 % and 6.94 % in the AF, IF, UIF-150, UIF-300 and UIF-450 groups, respectively, and the trend of porosity in potatoes was similar to that of beef. Meanwhile, the contents of volatile flavour components in the dishes were remarkably decreased after freezing treatments, and UIF treatment could promote the retention of volatile flavour components. Results of this study provided a reference for the application of UIF technology in the frozen quality enhancement of prepared dishes and their industrialisation.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"119 ","pages":"Article 107373"},"PeriodicalIF":8.7,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143942541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amir Shafaei Fallah, Fateme Asadi Touranlou, Mitra Rezaie
{"title":"Ultrasound technology and tomato industry: A review","authors":"Amir Shafaei Fallah, Fateme Asadi Touranlou, Mitra Rezaie","doi":"10.1016/j.ultsonch.2025.107374","DOIUrl":"10.1016/j.ultsonch.2025.107374","url":null,"abstract":"<div><div>Recent research emphasizes the potential of ultrasound technology in the food industry, particularly in tomato processing. Ultrasound’s non-invasive nature has made it a preferred choice for researchers seeking extraction and cavitation power without significantly altering sample properties. The concept of waste valorization, which involves transforming waste materials into valuable resources, is gaining traction worldwide as it helps reduce carbon footprints and pollution. Tomato processing yields significant waste, such as peels and seeds, which contain high levels of antioxidants and fiber, making them valuable resources for the food industry. This review examines the diverse applications of ultrasound technology in the tomato industry, focusing on its effects on the extraction of bioactive compounds, inhibition of microbial growth, enhancement of tomato germination, and removal of agrochemicals. Findings show that ultrasound-assisted extraction (UAE) increases yields of pectin and lycopene by 34–77% compared to conventional methods, reduces pesticide residues by up to 97%, and enhances germination rates by up to 43% when combined with technologies like plasma-activated water or ozone. Ultrasound significantly reduces bacteria, phytoviruses, yeasts, and molds, with reductions of 1.5–3.4 log CFU/g in tomato products. However, ultrasound treatment may affect seedling vigor due to reactive oxygen species generation. Further research is needed to optimize ultrasound parameters for diverse crops and integrate it with emerging technologies to maximize industrial scalability.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"118 ","pages":"Article 107374"},"PeriodicalIF":8.7,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143917419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jin Luo , Li Liang , Yongzhao Bi , Xialei Liu , Kaina Qiao , Zunying Liu , Xiangzhao Mao , Baoguo Sun , Yuyu Zhang
{"title":"Synergistic effects of mannoprotein and ultrasound on the interfacial properties, flavor, and structure of yeast protein","authors":"Jin Luo , Li Liang , Yongzhao Bi , Xialei Liu , Kaina Qiao , Zunying Liu , Xiangzhao Mao , Baoguo Sun , Yuyu Zhang","doi":"10.1016/j.ultsonch.2025.107372","DOIUrl":"10.1016/j.ultsonch.2025.107372","url":null,"abstract":"<div><div>To expand the application of yeast protein (YP) in the food industry, the synergistic effects of mannoprotein (MP) and ultrasound (US) treatment were explored to improve its solubility, flavor, and structural properties. Results showed that YP and MP formed YP-MP conjugation in 1:3 (<em>w</em>:<em>w</em>), after reacting with citric acid and sodium bicarbonate for 4 h at room temperature and ultrasonic treatment at 1000 W for 30 min. The YP-MP-US sample achieved a maximum protein yield of 54.82 ± 1.67 %. Furthermore, the protein particle size was reduced from 257.67 nm to 159.33 nm after the treatment, thereby improving its solubility, emulsifying, and foaming capacities. Sensory evaluations, combined with E-tongue, E-nose, and HS-SPME-GC–MS analyses, revealed a significant reduction in the unpleasant yeast flavor of YP (<em>p</em> < 0.05). Additionally, the synergistic treatment had altered the conformation and structure of YP, which were confirmed by the notable increase in β-sheet, free sulfhydryl (–SH) groups, surface hydrophobicity, and intrinsic fluorescence while promoting a looser and finer aggregation microstructure. In conclusion, the synergistic treatment significantly improved protein solubility and flavor, thereby enhancing its processing functionality.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"118 ","pages":"Article 107372"},"PeriodicalIF":8.7,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jiaxing Zheng , Yuzhu Zha , Mengyu Feng , Minglei Shan , Yu Yang , Cheng Yin , Qingbang Han
{"title":"Numerical investigation on jet-enhancement effect and interaction of out-of-phase cavitation bubbles excited by thermal nucleation","authors":"Jiaxing Zheng , Yuzhu Zha , Mengyu Feng , Minglei Shan , Yu Yang , Cheng Yin , Qingbang Han","doi":"10.1016/j.ultsonch.2025.107365","DOIUrl":"10.1016/j.ultsonch.2025.107365","url":null,"abstract":"<div><div>Understanding the formation and interactions of out-of-phase cavitation bubbles is crucial for comprehensively exploring cavitation processes in both nature and engineering applications. In this study, a numerical model for the interaction of out-of-phase cavitation bubbles is developed using the hybrid thermal lattice Boltzmann method, where cavitation bubbles are solely excited by thermal nucleation. Furthermore, a new temperature distribution function for thermal nucleation is proposed, enabling a more stable generation of cavitation bubbles. By comparing the results with those obtained from the Rayleigh–Plesset equation incorporating the thermal effect term, the validity of the thermal nucleation model has been verified. Subsequently, the validity of two out-of-phase cavitation bubbles model is experimentally verified, and the dynamic and thermodynamic behaviors of two out-of-phase cavitation bubbles are systematically investigated. The behaviors are primarily influenced by the dimensionless bubble spacing <span><math><msubsup><mrow><mi>l</mi></mrow><mrow><mn>0</mn></mrow><mrow><mo>∗</mo></mrow></msubsup></math></span> and the dimensionless phase difference <span><math><mrow><mi>Δ</mi><msup><mrow><mi>θ</mi></mrow><mrow><mo>∗</mo></mrow></msup></mrow></math></span>. Specifically, when <span><math><mrow><msubsup><mrow><mi>l</mi></mrow><mrow><mn>0</mn></mrow><mrow><mo>∗</mo></mrow></msubsup><mo>≥</mo><mn>1</mn><mo>.</mo><mn>00</mn></mrow></math></span>, weak interaction is observed, and no penetration phenomenon occurs. When <span><math><mrow><msubsup><mrow><mi>l</mi></mrow><mrow><mn>0</mn></mrow><mrow><mo>∗</mo></mrow></msubsup><mo><</mo><mn>1</mn><mo>.</mo><mn>00</mn></mrow></math></span> and <span><math><mrow><mi>Δ</mi><msup><mrow><mi>θ</mi></mrow><mrow><mo>∗</mo></mrow></msup><mo><</mo><mn>0</mn><mo>.</mo><mn>50</mn></mrow></math></span>, strong interaction is observed, and a penetration phenomenon occurs. Finally, the jet-enhancement effect of two out-of-phase cavitation bubbles is explored. The results indicate that when <span><math><mrow><msubsup><mrow><mi>l</mi></mrow><mrow><mn>0</mn></mrow><mrow><mo>∗</mo></mrow></msubsup><mo>=</mo><mn>0</mn><mo>.</mo><mn>78</mn></mrow></math></span>, the optimal jet-enhancement effect can be achieved by maintaining <span><math><mrow><mi>Δ</mi><msup><mrow><mi>θ</mi></mrow><mrow><mo>∗</mo></mrow></msup><mo>=</mo><mn>0</mn><mo>.</mo><mn>67</mn></mrow></math></span>. These findings provide important numerical insights for optimizing jet-enhancement in cavitation-related technologies.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"118 ","pages":"Article 107365"},"PeriodicalIF":8.7,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143899276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}