Ultrasonics Sonochemistry最新文献

{"title":"Ultrasound-assisted green synthesis of silver nanoparticles using Ruta graveolens L. Extract and antitumor evaluation","authors":"Nikita Gandlevskiy ,&nbsp;Altevir Rossato Viana ,&nbsp;Gabriel Toneto Druzian ,&nbsp;Daiana Kaminski Oliveira ,&nbsp;Andre Passaglia Schuch ,&nbsp;Alessandro Barge ,&nbsp;Giancarlo Cravotto ,&nbsp;Erico Marlon Moraes Flores","doi":"10.1016/j.ultsonch.2025.107340","DOIUrl":"10.1016/j.ultsonch.2025.107340","url":null,"abstract":"<div><div>This study aims to evaluate the ultrasound-assisted synthesis of silver nanoparticles (AgNPs) based on an aqueous extract of <em>Ruta graveolens</em> L. to reduce Ag⁺ to Ag⁰. In addition, the biological activity of the synthesized AgNPs was evaluated against tumor cells. The following parameters were evaluated for the synthesis: proportion between Ag⁺ solution (0.1 mol L^-1 Ag⁺) and <em>R. graveolens</em> L. extract, pH of <em>R. graveolens</em> L. extract (5, 7, and 9), temperature of solution containing Ag⁺ and <em>R. graveolens</em> L. extract, ultrasound (US) type (bath and probes), and the parameters for US as frequency (37, and 80 kHz for bath and 20 kHz for probes), amplitude and time of application of US. In order to confirm the US effect, “silent” experiments (without US) were performed. Using the optimized conditions (US bath, proportion between Ag⁺ solution and <em>R. graveolens</em> L. of 1 + 5, v v^-1, 80 kHz, 70 % amplitude, 70 °C, pH 9, and 25 min of sonication time) it was possible to obtain mean size, PI, and zeta potential of AgNPs of 30 nm, 0.129, −34.44 mV, respectively. For comparison of results, AgNPs synthesized in the “silent” condition presented mean size, PI, and zeta potential of 66 nm, 0.412, and –22.12 mV, respectively. The US synthesized AgNPs were lower, more uniform, and stable when compared with magnetic stirring. In addition, the morphology of AgNPs using US was predominantly spherical and monodisperse. The biological activity using cell lines HaCat (keratinocytes), L929 (fibroblasts), and B16-F10 (melanoma) against nanoparticles synthesized using US was evaluated against the different cell lines and the antioxidant activity of the AgNPs was measured by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. A higher cytotoxic effect on the melanoma cell line (IC₅₀ = 2.12 µg mL⁻¹) compared to normal cells. A good result was found in the DPPH assay, with an IC₅₀ of 234.3 µg mL⁻¹ for free radical scavenging. Therefore, the US technology presents a promising and sustainable green method avoiding the use of toxic reagents and obtained AgNPs showed potent anticancer activity.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107340"},"PeriodicalIF":8.7,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143868839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ball motion and bubble ripples in the interaction of cavitation bubble-elastic ball-curved wall","authors":"Yanyang Liu ,&nbsp;Jing Luo ,&nbsp;Lixin Bai ,&nbsp;Jiankun Hu","doi":"10.1016/j.ultsonch.2025.107348","DOIUrl":"10.1016/j.ultsonch.2025.107348","url":null,"abstract":"<div><div>Elastic ball motion and cavitation bubble ripples in cavitation bubble-elastic ball-curved wall interaction was investigated experimentally using single-electrode periodic discharge bubble generation technology and high-speed photography. It was found that the hard ball undergoes a process of “push-pull-push-pull” as the dimensionless bubble-ball distance increases, while the elastic ball undergoes a process of “push-pull” in the same scenario. This is mainly due to the combined effects of the expansion ejection effect, the reverse thrust of liquid jet and the secondary Bjerknes force of cavitation bubble and its rebound bubble, which are strengthened or weakened. The radial vibration of the elastic ball causes a continuous secondary Bjerknes force attraction effect between the ball and the wall, similar to that between an acoustic bubble and a wall. In the interaction of “cavitation bubble-elastic ball-curved wall,” there is a state of equilibrium stability where the centerline of the “bubble-ball” coincides with the centerline of the “bubble-wall.” Both the ball and the bubble will move towards this equilibrium position. This is a result of the three forces with different starting and ending points—the “bubble-wall” secondary Bjerknes force, the “ball-wall” secondary Bjerknes force, and the “bubble-ball” interaction force—reaching a condition of equilibrium. The evolution of the cavitation bubble is usually dominated by toroidal jets, sometimes forming multi-layered nested toroidal jets (annular cylindrical jet). The surface tension waves of the bubble, the elastic modulus waves and the curvature waves of the elastic ball work together to form cavitation bubble ripples. Under the primary intensification of the bubble’s rapid collapse and the secondary intensification of the wall effect, the bubble ripples are reinforced, leading to the formation of multi-layered nested toroidal jets.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107348"},"PeriodicalIF":8.7,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143839143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced sonophotocatalytic degradation of phthalate acid ester using copper-chromium layered double hydroxides on carbon nanotubes and biochar","authors":"Tannaz Sadeghi Rad ,&nbsp;Alireza Khataee ,&nbsp;Emine Sevval Yazici ,&nbsp;Erhan Gengec ,&nbsp;Mehmet Kobya ,&nbsp;Yeojoon Yoon","doi":"10.1016/j.ultsonch.2025.107351","DOIUrl":"10.1016/j.ultsonch.2025.107351","url":null,"abstract":"<div><div>Layered double hydroxides (LDHs) are lamellar and stable nanocatalysts driven by visible light. They have received much attention in the context of advanced oxidation processes. Their catalytic performance is remarkably restricted owing to undesired aggregation and the possibility of electron-hole recombination. To address these issues, we engineered carbon-nanotube (CNT)-and biochar (BC)-based CuCr LDH nanocomposites via a facile hydrothermal method. The synthesized nanocomposites were physically and chemically characterized using various methods. The performances of the BC-CuCr LDH and CNT-CuCr LDH nanocomposites were compared during the sonophotocatalytic degradation of dimethyl phthalate. With 1.5 g L^-1 of BC-CuCr LDH, complete degradation of dimethyl phthalate was achieved within 25 min under 50 W light intensity and 150 W ultrasound irradiation with a synergy factor of 14. The critical roles of the hydroxyl and superoxide radicals were confirmed by the addition of several inhibitors. Ultimately, six possible intermediates generated during the sonophotocatalytic process were identified using gas chromatography-mass spectrometry (GCMS).</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107351"},"PeriodicalIF":8.7,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143850547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sequential recovery of alginate from fucoidan extraction by-products of Nizamuddinia zanardinii seaweed using green extraction methods","authors":"Mehdi Alboofetileh ,&nbsp;Samira Jeddi ,&nbsp;Mehdi Abdollahi","doi":"10.1016/j.ultsonch.2025.107343","DOIUrl":"10.1016/j.ultsonch.2025.107343","url":null,"abstract":"<div><div>The effects of green technologies-ultrasound, microwave and their combined application-on alginate extraction from fucoidan production by-products of brown seaweed (<em>Nizamuddinia zanardinii</em>) were compared with the conventional alkaline method. The impact of the extraction methods on the Fourier-transform infrared spectroscopy (FT-IR) spectra, molecular weight, antioxidant, rheological, emulsifying and foaming properties of the recovered alginates was also evaluated. The highest (15.36 % w/w) and lowest (11.88 % w/w) alginate yields were obtained using the microwave and conventional methods, respectively. Using ultrasound (2362 kDa) and ultrasound-microwave (2608 kDa) led to a significant reduction (<em>p</em> &lt; 0.05) in the average molecular weight of alginate in comparison to the microwave (3015 kDa) and alkaline methods (3021 kDa). The microwave-extracted alginate showed the highest DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity (19.98 %-35.60 %) and ferric reducing antioxidant power (FRAP) (0.138–177 abs) of the extracted alginates. The rheological properties of the alginates were affected by the extraction method, resulting in the highest viscosity in the microwave- and conventionally-extracted alginate. Also, all the extracted alginates showed moderate emulsifying and foaming properties. Overall, the findings highlight the great potential of green technologies to enhance the recovery and functionality of alginate from fucoidan extraction by-products, advancing the efficient biorefining of brown seaweed.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107343"},"PeriodicalIF":8.7,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143826029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the dual reactivity of nanoscaled PuO2 sonicated in oxygenated aqueous solutions","authors":"Julien Margate ,&nbsp;Matthieu Virot ,&nbsp;Thomas Dumas ,&nbsp;Simon Bayle ,&nbsp;Denis Menut ,&nbsp;Laura Bonato ,&nbsp;Emilie Broussard ,&nbsp;Fanny Molière ,&nbsp;Charles Hours ,&nbsp;Laurent Venault ,&nbsp;Sergey I. Nikitenko","doi":"10.1016/j.ultsonch.2025.107346","DOIUrl":"10.1016/j.ultsonch.2025.107346","url":null,"abstract":"<div><div>While bulk PuO₂ is known to be strongly resistant to dissolution, even under ultrasonic irradiation, this study demonstrates that nanometric PuO₂ samples can exhibit enhanced reactivity when sonicated under an Ar/(20 %)O₂ atmosphere. Sonication of powdered PuO₂ nanoparticles (∼5 nm) in pure water was found to be ineffective. In contrast, colloidal PuO₂ nanoparticles (∼3 nm) prepared via hydrolysis exhibited markedly different behavior, leading to the accumulation of Pu(VI), with sonochemically-generated H₂O₂ playing a crucial role in the process. Further investigations identified an intermediate species implicated in the dissolution process, agreeing with a recently described Pu(IV) peroxide compound. Despite the chemical similarity of the PuO₂ nanoparticles, this study highlights their dual reactivity under conditions favoring H₂O₂ formation highlighting an important role of the material’s preparation method. Beyond underscoring the critical role of H₂O₂ in the reactivity of PuO₂ nanoparticles, this study also evidences a potential pathway for their transformation under environmental conditions where radiolysis can generate similar chemical environments.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107346"},"PeriodicalIF":8.7,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-assisted optimization extraction and biological activities analysis of flavonoids from Sanghuangporus sanghuang","authors":"Yanhua Wang ,&nbsp;Chen Zhang ,&nbsp;Yilin Zhao ,&nbsp;Fuhua Wu ,&nbsp;Yaoli Yue ,&nbsp;Yingjun Zhang ,&nbsp;Dandan Li","doi":"10.1016/j.ultsonch.2025.107326","DOIUrl":"10.1016/j.ultsonch.2025.107326","url":null,"abstract":"<div><div>The fungus <em>Sanghuangporus sanghuang</em> possesses notable medicinal and edible characteristics, displaying a diverse array of biological functionalities. This research endeavor seeks to investigate the procedure of extracting flavonoids from <em>S. sanghuang</em>, and the qualitative and quantitative analysis of flavonoids extraction from <em>S. sanghuang</em> using ultra-performance liquid chromatography (UPLC), and assess its antioxidant capacity and potential antiproliferative properties. The ultrasonic-assisted extraction resulted in a 2.34-fold increase compared to the hot water extraction method. Response surface methodology (RSM) was employed to enhance the extraction process of flavonoids from <em>S. sanghuang</em>. The results indicated that the optimal extraction rate of <em>S. sanghuang</em> flavonoids were achieved at 16.16 ± 0.12 %. This was attained at an ultrasound temperature of 50°C using 80 % ethanol concentration and an ultrasound extraction time of 60 min. The <em>S. sanghuang</em> extract was analyzed using UPLC, resulting in the identification of twenty-six distinct compounds. The flavonoids derived from <em>S. sanghuang</em> have demonstrated the ability to effectively scavenge DPPH, superoxide anions (O₂^–·), and hydroxyl free radicals (^·OH), in addition to exhibiting ferric reducing power. Furthermore, it exhibited inhibitory effects on α-glucosidase. The Pearson correlation analysis revealed a statistically significant positive correlation between the antioxidant capacities, encompassing DPPH, O₂^–·, ^·OH, ferric reducing power, and the inhibited α-glucosidase capability. It has been determined that the activity of α-glucosidase can be inhibited by <em>S. sanghuang</em> flavonoids, and this inhibition can be predicted using a model developed with the MATLAB program. In the current investigation, the study successfully demonstrated the inhibitory effects of <em>S. sanghuang</em> flavonoids on cell proliferation and migration in glioma cells. This was achieved through the analysis of CCK-8 assay and wound healing assay, with statistical significance observed (<em>p</em> &lt; 0.05).</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107326"},"PeriodicalIF":8.7,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143834128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing ultrasound applications through shell-less nanobubbles: A study on acoustic and optical properties","authors":"Zong-Han Hsieh ,&nbsp;Cheng-An J. Lin ,&nbsp;Chih-Kuang Yeh","doi":"10.1016/j.ultsonch.2025.107336","DOIUrl":"10.1016/j.ultsonch.2025.107336","url":null,"abstract":"<div><div>Histotripsy employs acoustic inertial cavitation to mechanically destroy tissue, producing acellular debris. While introducing bubbles can lower the cavitation threshold and enhance treatment efficiency, micrometer-scale bubbles struggle to penetrate tissues effectively. Shell-less nanobubbles, with their high internal pressure, stability, negatively charged surfaces, and unique lifetimes ranging from weeks to months, offer a promising alternative. However, their interactions with ultrasound remain unexplored. This study used a claw-type pump nanobubble generator to produce nanobubbles and employed acoustic and optical methods to observe their behavior under high-intensity ultrasound exposure. The results demonstrated that the device generated nanobubble solutions with an average particle size of 107 nm, a concentration of 1.94 × 10⁹ particles/mL, a lifetime exceeding one week, and a zeta potential of −21.2 mV. Acoustic and optical observations further revealed that nanobubble solutions reduced the inertial cavitation threshold of the liquid from 26.5 MPa to 10.3 MPa. These findings suggest a potential strategy to enhance the efficiency of ultrasound histotripsy treatments.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107336"},"PeriodicalIF":8.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143815974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Comparison between hydrodynamic and ultrasound cavitation on the inactivation of lipoxygenase and physicochemical properties of soy milk” [Ultrason. Sonochem. 101 (2023) 1–12]","authors":"Guangjie Xie ,&nbsp;Ji Luo ,&nbsp;Fang Li ,&nbsp;Dandan Li ,&nbsp;Yongbin Han ,&nbsp;Yang Tao","doi":"10.1016/j.ultsonch.2025.107335","DOIUrl":"10.1016/j.ultsonch.2025.107335","url":null,"abstract":"","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107335"},"PeriodicalIF":8.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing structural and functional properties of commercially available pea protein isolate for plant-based meat analogues using combined pH-Shift, high-intensity ultrasound, and heat treatments","authors":"Assam Bin Tahir ,&nbsp;Anees Ahmed Khalil ,&nbsp;Hina Gull ,&nbsp;Khubaib Ali ,&nbsp;Najla AlMasoud ,&nbsp;Taghrid S. Alomar ,&nbsp;Abderrahmane Aït-Kaddour ,&nbsp;Rana Muhammad Aadil","doi":"10.1016/j.ultsonch.2025.107342","DOIUrl":"10.1016/j.ultsonch.2025.107342","url":null,"abstract":"<div><div>Diets based on pea protein have gained international recognition as a good substitute for meat or other main sources of protein. However, problems like gelling and emulsifying qualities make it difficult to use pea protein. To successfully overcome significant obstacles related to the use of pea protein in many industrial sectors, particularly meat, this study offers a combination of methods used to produce commercially accessible Pea Protein Isolate (PPI). High-intensity ultrasound (HIUS) at three magnitudes (2, 4, and 8 W/mL), heat at 60 °C, and pH at 10.0 were all integrated within the set. For artificial meat, PUHP₂, PUHP₄, and PUHP₈ were the most promising of the nine treatments. After undergoing combined treatments (pH-shift, HIUS, and heat), favorable gelling was shown by treatments, emulsifying, and foaming properties while containing the ideal and desired protein size, as understood by the results in the gel electrophoresis. When treated PPIs were used to stabilize the sunflower oil-in-water emulsion, the emulsion capacity increased significantly for PUHP₂, PUHP₄, and PUHP₈ (43.47 %, 46.57 %, and 40.90 % increase, respectively). Furthermore, solubility (for PUHP₂, PUHP₄, and PUHP₈) had shown considerable (p &lt; 0.05) improvement from 31.03 % ± 2.11 % (DPPI) to 53.33 % ± 2.3 %, 55.13 % ± 1.0 %, and 58.43 % ± 3.2 %, in SEM which accompanied by differences in the morphology of protein. This study’s gelling properties (2.512 ± 0.1 N, 2.604 ± 0.1 N, and 2.168 ± 0.3 N, for PUHP₂, PUHP₄, and PUHP₈) were crucial, primarily from the standpoint of plant-based meat analogs. The processes proposed by this study pea protein will be enabled that has undergone this series of chemical and physical processes to proceed in the direction of far better meat substitutes. Overall, this research contributes to the advancement of pea protein’s use as an industrial protein and allows better usage of its hypoallergenic, non-GMO and high protein content.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107342"},"PeriodicalIF":8.7,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143800389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drying kinetics and thermodynamic analysis; enhancing quinoa (Chenopodium quinoa Willd.) quality profile via pre-treatments assisted germination and processing","authors":"Jabir Khan ,&nbsp;Palwasha Gul ,&nbsp;Qingyun Li ,&nbsp;Kunlun Liu","doi":"10.1016/j.ultsonch.2025.107337","DOIUrl":"10.1016/j.ultsonch.2025.107337","url":null,"abstract":"<div><div>Pre-treatments assisted germination is an efficient technique to enhance the nutritional profile of Quinoa (<em>Chenopodium quinoa Willd.)</em>. The present study investigated the impact of pre-treatments assisted germination of quinoa nutritional, anti-nutritional, and structural properties. Quinoa grains JQ-778 were subjected to various pre-treatments including soaking, ultrasound at 28 kHz &amp;40 kHz (US 28 kHz, US 40 kHz) for 30 min followed by germination over 96-hour at 25 °C in a Biochemical-Incubator, 12/12 h dark and light dried at temperatures 50 °C, 60 °C, 70 °C, and combined temperatures (70 °C, 60 °C, 50 °C). Among evaluated models, page and logarithmic showed the best fit, presenting the highest, R² ≥ 0.9991, X² ≤ 0.0013, RMSE ≤ 0.0022, and RSS ≤ 0.0201. Moisture diffusion varied from 3.74 × 10⁻⁹ to 8.36 × 10⁻⁹, with R² 0.9272 to 0.9837, and energy activation from 18.25 to 28.41 kJ/mol with R² 0.9533–0.9896. US 40 kHz significantly lowered drying time without affecting germinated quinoa grains bioactive components or other qualitative factors. Ultrasonic pre-treatment at 40 kHz and drying at 60 °C yielded the highest antioxidant potency composite index of 98.78 %. The content<!--> <!-->of phytic acid and tannin dropped by 66.66 to 82.99 % and 31.48 to 41.60 %, respectively (p &lt; 0.05). Each treatment significantly altered quinoa’s quality attributes. Principal Component Analysis revealed significant correlations between analyses, explaining 80.37 % variability. The intensity of functional groups decreased in the infrared spectra, although the transmission of signals was greater in pretreated samples than in control. Scanning electron microscopy analysis showed extensive fragmentation and surface erosion of quinoa grains after ultrasound treatment. Our data suggests that ultrasound-treated quinoa grains may enhance their nutritional value, making them a suggested source of high-protein grains, bioactive components, with distinct structural properties.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107337"},"PeriodicalIF":8.7,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143834127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}