Ultrasonics Sonochemistry最新文献

{"title":"Ultrasound-assisted enhancement of bioactive compounds in hawthorn vinegar: A functional approach to anticancer and antidiabetic effects.","authors":"Selim Öğüt, Melikenur Türkol, Seydi Yıkmış, Esra Bozgeyik, Gholamreza Abdi, Emine Kocyigit, Rana Muhammad Aadil, Nilay Seyidoglu, Deniz Karakçı, Nazlı Tokatlı","doi":"10.1016/j.ultsonch.2025.107245","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2025.107245","url":null,"abstract":"<p><p>In this study, the effects of ultrasound treatment on bioactive components and functional properties of hawthorn vinegar (Crataegus tanacetifolia) were investigated. Parameters such as total phenolic compound (TPC), total flavonoid content (TFC), ascorbic acid (AA), DPPH radical scavenging activity and CUPRAC reducing capacity were optimised by surface response method (RSM) and 14 min duration and 61.40 % amplitude were determined as the most suitable treatment conditions. The results showed that ultrasound treatment improved the antioxidant properties of hawthorn vinegar by increasing TPC, TFC, DPPH and CUPRAC values. In addition, it was observed that hawthorn vinegar samples exhibited anticancer effects in cell culture experiments. In experiments on A549 (lung), MCF-7 (breast) and HT-29 (colon) cancer cell lines, ultrasound-treated vinegar increased apoptotic effects, suppressed cell migration and reduced necrosis rates in some cell lines. In particular, ultrasound treatment of vinegar resulted in a reduction in the expression of anti-apoptotic genes (BCL-2 and XIAP) and an enhancement in the expression of pro-apoptotic genes (BAX). These findings suggest that ultrasound technology preserves and enhances the bioactive components of hawthorn vinegar, improves its anticancer properties and increases its potential for use as a functional food product.</p>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"114 ","pages":"107245"},"PeriodicalIF":8.7,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143062976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative strategy for full-scale polar components explicition and ultrasonic-assisted optimization of Astragalus membranaceus flower.","authors":"Yumei Wang, Meiling Gu, Meng Zhang, Jialin Mao, Yujian Han, Qi Liu","doi":"10.1016/j.ultsonch.2025.107238","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2025.107238","url":null,"abstract":"<p><p>Traditional extraction under merely one specific solvent was confronted with incomplete phytochemical unscramble problem. In view of this, in order to obtain the overall chemical understanding, we attempted to use Astragalus membranaceus flower, an abundant exploitable resource, to screen a novel extraction mixing scheme via gradient solvents based on the ions' quantity detected in UHPLC-Q-TOF-MS/MS approach. Samples were firstly extracted by different concentration ethanol, and then, six mixing schemes were investigated and one scheme with maximum detected ions was screened out. After identification procedures based on an comprehensive reference database, 136 components covered 54 flavonoids were accurately identified, indicating that flavonoids may played a critical role in Astragalus membranaceus flower. Through the Box-Behnken Design optimization, 29.79 mg/g of flavonoids were extracted under ethanol concentration of 35 %, solid-liquid ratio of 1:50, extraction time of 50 min. The experiments showed that the established mixing scheme could obtain more comprehensive ingredients compared to orthodox extraction, further guide the optimization of significative ingredients scientifically. The present paper could promote the development of Astragalus membranaceus flower.</p>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"114 ","pages":"107238"},"PeriodicalIF":8.7,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143062971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilizing ultrasound for the extraction of polysaccharides from the tuber of Typhonium giganteum Engl.: Extraction conditions, structural characterization and bioactivities.","authors":"Xi Peng, Jing-Ya Wang, Kui-Xu Gao, Zhi-Kun Wang, Qiao-Ling Deng, Yao Wang, Mei-Bian Hu, Yu-Jie Liu","doi":"10.1016/j.ultsonch.2025.107243","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2025.107243","url":null,"abstract":"<p><p>Polysaccharides from the dried tuber of Typhonium giganteum Engl. (TGEPs) were obtained by utilizing ultrasonic-assisted extraction (UAE) as the extraction method. The determination of optimal process parameters for the UAE of TGEPs (TGEP-U) was accomplished through the application of response surface methodology (RSM). The structural characteristics, antioxidant and hypoglycemic effects of TGEP-U and TGEPs obtained by hot water extraction (TGEP-H) were then compared. Consequently, the optimum extraction conditions predicted by RSM for TGEP-U were obtained as adding water at a ratio of 31 mL/g and extracted for 32 min under an ultrasound power of 440 W. In the verification experiment, the actual yield of TGEP-U was 7.32 ± 0.18 %. It was found that UAE could increase the yield and the total sugar content of TGEPs. Meanwhile, chemical composition analysis showed that both TGEP-U and TGEP-H were mainly composed of mannose, rhamnose, glucuronic acid, galacturonic acid, glucose, galactose, arabinose, and fucose, but the monosaccharide molar ratios were changed by UAE. Analysis of molecular weight (Mw) revealed the presence of three primary constituents within TGEP-U, and four main components in TGEP-H, and UAE reduced the average Mw of TGEPs. No obvious difference was found in the Fourier transform infrared spectroscopy analysis of TGEP-U and TGEP-H. The Congo red and Circular dichroism tests demonstrated that TGEP-U and TGEP-H had non-three helical structure. Scanning electron microscope observation further revealed that the aggregation of functional groups within TGEPs may be influenced by ultrasound, thereby affecting their powder morphology. TGEP-U has slightly poorer thermal stability than TGEP-H, which may be affected by ultrasonic cavitation effects. The results also indicated that TGEP-U had better antioxidant and hypoglycemic activity than TGEP-H. In summary, UAE is an effective method to extract and enhance the activity of TGEPs with enormous research value and potentials.</p>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"113 ","pages":"107243"},"PeriodicalIF":8.7,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional nanocrystal as effective contrast agents for dual-mode imaging: Live-cell sonoluminescence and contrast-enhanced echography.","authors":"V Vighetto, E Pascucci, N M Percivalle, A Troia, K M Meiburger, M R P van den Broek, T Segers, V Cauda","doi":"10.1016/j.ultsonch.2025.107242","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2025.107242","url":null,"abstract":"<p><p>In the context of molecular imaging, the present work explores an innovative platform made of lipid-coated nanocrystals as contrast-enhanced agent for both ultrasound imaging and sonoluminescence. At first, the dynamics of gas bubbles generation and cavitation under insonation with either pristine or lipid-coated nanocrystals (ZnO-Lip) are described, and the differences between the two colloidal systems are highlighted. These ZnO-Lip show an unprecedented ability to assist cavitation, which is reflected in enhanced sonoluminescent light emission with respect to the pristine nanocrystals or the pure water. Highly defined and sharp sonoluminescent images of cultured cells are indeed obtained, for the first time, when ZnO-Lip are used. Furthermore, ZnO-Lip were adopted as a nanosized agent for contrast-enhanced ultrasound imaging, i.e. echography, first in solutions, and then on ex-vivo tissues. A prolonged over time and bright imaging effect is observed when adopting the developed nanoparticles. Furthermore, their nanometric size and potential targeting with biomolecules would allow ease extravasation and tissue or even cell penetration, achieving enhanced-contrast imaging. Finally, the stimuli-responsive therapeutic applications of ZnO-Lip against tumors is overviewed, aiming to achieve a fully theranostic approach.</p>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"113 ","pages":"107242"},"PeriodicalIF":8.7,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143057648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Process, dynamics and bioeffects of acoustic droplet vaporization induced by dual-frequency focused ultrasound","authors":"Yubo Zhao, Yi Feng, Liang Wu","doi":"10.1016/j.ultsonch.2025.107234","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2025.107234","url":null,"abstract":"Acoustic droplet vaporization (ADV) plays a crucial role in ultrasound-related biomedical applications. While previous models have examined the stages of nucleation, growth, and oscillation in isolation, which may limit their ability to fully describe the entire ADV process. To address this, our study developed an integrated model that unifies these three stages of ADV, stimulated by a continuous nonlinear dual-frequency ultrasound wave. Using this integrated model, we investigated the influence of nonlinear dual-frequency ultrasound parameters on ADV dynamics and bioeffects by incorporating tissue viscoelasticity through parametric studies. Our results demonstrated that the proposed model accurately captured the entire ADV process, ensuring continuous vapor bubble formation and evolution throughout the phase transition process. Moreover, the applied unified theory for bubble dynamics can simulate intense bubble collapse with high Mach Number as a result of the nonlinear effects of dual-frequency ultrasound. In addition, cavitation-associated mechanical and thermal damage appeared to be more strongly correlated with rapid bubble collapse than with maximum bubble size. Our research also revealed that the mechanical and thermal effects could be regulated independently to some extent by adjusting dual-frequency ultrasound parameters, as they presented differing sensitivities to frequency and acoustic power. Importantly, dual-frequency combinations such as 1.5 MHz + 3 MHz (fundamental and second harmonic), which exhibit a higher Degree of Nonlinearity (DoN) can extend bubble lifespan, offering a potential pathway to the efficacy of ultrasound treatments.","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"34 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of hydrodynamic cavitation combined with snail enzyme treatment on the structure and functional properties of water-soluble dietary fiber in rice husks.","authors":"Zhigang Quan, Mingming Chen, Dongjie Zhang","doi":"10.1016/j.ultsonch.2025.107236","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2025.107236","url":null,"abstract":"<p><p>In this study, we adopted the synergistic modification technology of hydrodynamic cavitation and snail enzyme, to improve the yield and activity of soluble dietary fibers (SDFs) of rice husk. The physicochemical properties, structural changes, and inhibition of α-glucosidase and α-amylase of SDFs were examined in vitro. This synergistic treatment significantly increased the yield of SDFs to 18.64 % ± 0.16 %, significantly reduced the particle size to 122.33 ± 0.26 nm, and significantly increased the specific surface area to 1.718 ± 0.002 m²/g. The absolute value of the zeta potential significantly increased to -36.39 ± 0.12 mV, indicating an excellent solution stability and gel-forming ability. At the same time, the water-holding, oil-holding, and swelling capacities were significantly enhanced, reaching 8.52 ± 0.09 g/g, 4.85 ± 0.29 g/g, and 7.29 ± 0.25 mL/g, respectively. Structural analysis showed that the synergistic treatment destroyed the fiber structure, produced a large number of small molecule fragments, and significantly changed the monosaccharide components and functional group distribution. Functional evaluation showed that the inhibitory effect of CE-SDF on α-glucosidase and α-amylase was significantly enhanced, and enzymatic reaction kinetic analysis revealed that both enzymes were competitive inhibitors, with IC₅₀ values of 2.893 and 1.727 mg/mL, respectively. In summary, the synergistic modification of hydrodynamic cavitation and snail enzyme greatly optimized the structural and functional properties of rice husk SDFs, providing a theoretical basis for its application in the field of hypoglycemic drugs and functional foods.</p>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"113 ","pages":"107236"},"PeriodicalIF":8.7,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Focusing on the mechanism of glycinin-soybean lipophilic protein hybrid gels: Effect of ultrasonic, subunit interactions, and formation process analysis","authors":"Yuyang Huang, Jiyuan Liu, Yongping Li, Yongsheng Zhu, Gang Chen, Baoning Zheng, Yixin Zhang, Yang Li, Xiuqing Zhu","doi":"10.1016/j.ultsonch.2025.107239","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2025.107239","url":null,"abstract":"Heat facilitates aggregation and gel formation of soybean proteins. Ultrasonic reduces the size of protein aggregates. This study examined the impact of glycinin (11S) subunits on soybean lipophilic proteins (SLPs) gel formation and underlying mechanisms. Effects of protein dispersion pretreatment with 400 W ultrasonic and associated mechanisms were assessed. Addition of the A- and B-subunits before and after ultrasonic minimally affected SLP secondary structure. A-subunit addition before ultrasonic negligibly affected SLP tertiary structure. Addition of the B-subunit after ultrasonic reduced hydrophobic thermal aggregation. However, the small B-subunit size was unfavorable for the formation of a gel matrix, which led to poor gel properties. In contrast, solubility of the A-subunit after ultrasonic was increased to 31.06 ± 1.62 %). Particle size was decreased to 43.33 ± 1.36 nm for A:SLP (1:2). Endogenous fluorescence spectroscopy demonstrated increased protein unfolding after ultrasonic and decreased disulfide bonds. These changes improved the gel state. Rheological and microstructural analyses revealed increased energy storage modulus and yield strain, accompanied by a more homogeneous microstructure following ultrasonic. Microscopic improvement resulted in increased encapsulated water within interstitial spaces of the A-SLP gel matrix. This enhanced water mobility in B-SLP gels, in turn weakening gel stability. The changes observed in B-SLP were primarily due to reduced hydrophobic interactions between the proteins. The findings clarify the effect of ultrasonic treatment on the formation of soybean globulin-SLP hybrid gels at the subunit level. The data provide a theoretical basis for the synergistic utilization of soybean proteins among different components.","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"109 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of cavitation erosion behavior in wire-arc directed energy deposition and cast nickel-aluminum bronze alloys.","authors":"Xiang Cai, Mengmeng Yang, Shujun Li, Cheng Wang, Yanxin Qiao, Jian Zhou, Feng Xue","doi":"10.1016/j.ultsonch.2025.107235","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2025.107235","url":null,"abstract":"<p><p>In this study, the cavitation erosion (CE) behavior of wire-arc directed energy deposition (DED) nickel-aluminum bronze (NAB) alloys is compared with that of cast alloys, and the synergistic effect between corrosion and CE is investigated. The CE resistance of the wire-arc DED NAB alloy is better than that of the cast alloys. The CE of NAB alloys preferentially occurs at the boundaries of the α-Cu and residual β phases, and in the matrix around the κ phase. The residual β phase exhibits greater damage than the α-Cu phase. Throughout the CE, the alloys are dominated by local corrosion characteristics (selective-phase corrosion), while the wire-arc DED NAB alloys exhibit superior uniform corrosion characteristics. Notably, the uniform corrosion characteristics of all alloys are enhanced after CE. The mass loss caused by the synergistic effect of the cast NAB alloy and wire arc DED NAB alloy accounts for 56% and 52% of the total mass loss, with the corrosion-induced CE increment exceeding that of the CE-induced corrosion increment.</p>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"113 ","pages":"107235"},"PeriodicalIF":8.7,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synchronized acoustic emission and high-speed imaging of cavitation-induced atomization: The role of shock waves.","authors":"Abhinav Priyadarshi, Paul Prentice, Dmitry Eskin, Peter D Lee, Iakovos Tzanakis","doi":"10.1016/j.ultsonch.2025.107233","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2025.107233","url":null,"abstract":"<p><p>This study experimentally investigates the role of cavitation-induced shock waves in initiating and destabilizing capillary (surface) waves on a droplet surface, preceding atomization. Acoustic emissions and interfacial wave dynamics were simultaneously monitored in droplets of different liquids (water, isopropyl alcohol and glycerol), using a calibrated fiber-optic hydrophone and high-speed imaging. Spectral analysis of the hydrophone data revealed distinct subharmonic frequency peaks in the acoustic spectrum correlated with the wavelength of capillary waves, which were optically captured during the onset of atomization from the repetitive imploding bubbles. This finding provides the first direct evidence that the wavelength of the growing surface waves, which governs capillary instability resulting in droplet breakup, is linked to the periodicity of shock waves responsible for the onset of the subharmonic frequencies detected in the acoustic spectra. This work contributes to a deeper understanding of ultrasonic atomization, signifying the role of cavitation and shock waves in the atomization process.</p>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"113 ","pages":"107233"},"PeriodicalIF":8.7,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Ultrasound pre-fractured casein and in-situ formation of high internal phase emulsions\" [Ultrason. Sonochem. 64 (2020) 104916].","authors":"An-Qi Bi, Xian-Bing Xu, Yu Guo, Ming Du, Cui-Ping Yu, Chao Wu","doi":"10.1016/j.ultsonch.2025.107226","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2025.107226","url":null,"abstract":"","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":" ","pages":"107226"},"PeriodicalIF":8.7,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}