Ultrasonics Sonochemistry最新文献

{"title":"Ultrasound-assisted spray freeze-drying: a cutting-edge approach for gum Arabic cryogel powder production","authors":"Ahmadreza Esfandiari, Marzieh Rownaghi, Mehrdad Niakousari","doi":"10.1016/j.ultsonch.2025.107440","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2025.107440","url":null,"abstract":"Gum Arabic is a multifunctional natural polysaccharide that is widely used in the food and pharmaceutical industries, but its powdered form often exhibits poor structural and functional properties. Recent advances in spray freeze-drying (SFD) and ultrasound-assisted spray freeze-drying (US-SFD) present promising strategies for improving powder quality. While prior studies have explored basic SFD applications, limited attention has been paid to the impact of ultrasound during freezing on gum Arabic’s structure and functionality. This study aimed to evaluate how US-SFD affects the physicochemical and structural characteristics of gum Arabic cryogels at 1 and 3 % concentrations. Feed solutions were atomized into liquid nitrogen and freeze-dried, with ultrasound applied during freezing for selected samples. Bulk and tapped density, porosity, thermal behavior, morphology, crystallinity, color, and solubility were evaluated. US-SFD-1 % and US-SFD-3 % exhibited the lowest bulk densities (0.003 ± 0.000 and 0.006 ± 0.002 g/cm<ce:sup loc=\"post\">3</ce:sup>) and highest porosities (up to 99.660 ± 0.086 %), indicating the formation of highly porous, lightweight powders. FTIR revealed reduced O–H stretching intensities in US-SFD samples, suggesting alterations in hydrogen bonding, while XRD confirmed their amorphous nature. Color analysis showed SFD-1 % had the highest ΔE (25.260 ± 2.936), though SFD-3 % appeared more yellow. However, the study was limited by the absence of ultrasound intensity optimization and the evaluation of only a narrow concentration range. Future investigations should focus on a more comprehensive exploration of processing parameters and assess the functional applications of these cryogels in food, pharmaceutical, and biomedical industries.","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"15 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144335549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound pretreatment combined with emulsion coagulant: Synergistic effects on soybean protein gel properties and salt-coagulated tofu quality","authors":"Ying Xin,&nbsp;Dingyang Lv,&nbsp;Fute Du,&nbsp;Xiaofei Shi,&nbsp;Jinjie Yang,&nbsp;Tanghao Li","doi":"10.1016/j.ultsonch.2025.107437","DOIUrl":"10.1016/j.ultsonch.2025.107437","url":null,"abstract":"<div><div>Controlling the quality characteristics of tofu by adjusting the soybean protein gelling behavior has always been a challenging and intriguing task. While tofu prepared with emulsion coagulants exhibits high yield, it suffers from compromised gel strength and water-holding capacity. This study introduced ultrasound pretreatment coupled with emulsion coagulants to modulate soy protein gelation during tofu formation. The results demonstrated that the combined approach significantly enhanced textural parameters (hardness, gumminess, and chewiness) and water retention compared to emulsion coagulant alone. These improvements were primarily attributed to ultrasound-induced cavitation, which dissociated protein aggregates and exposed basic amino acid residues, free sulfhydryl groups, and hydrophobic domains. This structural modification reduced the particle size of soy milk and oil bodies, facilitated disulfide bond formation and hydrophobic interactions during coagulation, and ultimately improved gel strength. This structural modification reduced the particle size of soy milk and oil bodies, facilitated disulfide bond formation and hydrophobic interactions during coagulation, and ultimately improved gel strength. On this basis, the slow ion release from emulsion coagulants complemented these effects, promoting a uniform and dense gel network that effectively restricted water mobility in tofu. Furthermore, principal component analysis (PCA) revealed that ultrasound-coagulant coordination predominantly altered tofu hardness and water state through PC1 (46.45 % variance contribution). This dual-modulation strategy provides new insights for diversified, customized tofu production. The findings not only propose an innovative quality enhancement methodology but also offer empirical support for scaling up ultrasound applications in tofu industrialization.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"120 ","pages":"Article 107437"},"PeriodicalIF":8.7,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144335568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonlinear bubble dynamics in cryogenic two-phase flow under ultrasonic excitation considering mass transfer","authors":"Jin Zhang, Yu Zhang, Yong Chen, Xiaobo Rui, Congren Zheng, Yu Wu, Jie Yang, Hexin Gao, Lei Qi","doi":"10.1016/j.ultsonch.2025.107438","DOIUrl":"https://doi.org/10.1016/j.ultsonch.2025.107438","url":null,"abstract":"Bubble dynamics under ultrasonic excitation is the theoretical basis for ultrasonic measurement of gas-liquid two-phase flow. In cryogenic two-phase flow, bubble oscillation will be affected by vapor mass transfer due to the presence of liquid vapor. This article combines the ideal gas-liquid vapor assumption and the cryogenic fluid state equation to establish a numerical model of cryogenic bubble dynamics under ultrasonic excitation considering vapor mass transfer. The influences of ultrasonic excitation frequency, amplitude, and ambient pressure on bubble oscillations are analyzed through numerical calculations. The results indicate that considering vapor mass transfer, bubble resonant frequency and the variation of temperature change increases, while the variation of radius change decreases. When the ambient pressure is low and the ultrasonic excitation frequency is equal to the bubble’s resonant frequency, the vibration of bubbles exhibits obvious nonlinear characteristics, and it may cause bubble collapses at higher excitation amplitudes. By establishing a finite volume simulation model and comparing it with numerical calculations, the accuracy of the theoretical model is verified.","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"7 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144335550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization of ultrasound-assisted deep eutectic solvent extraction, characterization, and bioactivities of flavonoids from Cercis glabra leaves","authors":"Yu Meng ,&nbsp;Wenhao Zou ,&nbsp;Tingting Guo ,&nbsp;Lin Zhang ,&nbsp;Pengpai Zhang ,&nbsp;Penghua Shu","doi":"10.1016/j.ultsonch.2025.107434","DOIUrl":"10.1016/j.ultsonch.2025.107434","url":null,"abstract":"<div><div>This study presents an innovative and environmentally friendly approach for extracting flavonoids from <em>Cercis glabra</em> leaves using ultrasound − assisted deep eutectic solvent extraction (UAE − DESs). Through systematic evaluation of 22 deep eutectic solvent (DESs) formulations, choline chloride–levulinic acid (ChCl:Lev) was identified as the optimal solvent system. Response surface methodology optimization revealed ideal extraction parameters: a liquid – solid ratio of 25:1 mL/g, extraction temperature of 40 °C, time of 39 min, achieving a flavonoid yield of 8.01 mg/g. Compared with the conventional method (80 % ethanol), UAE − DESs exhibited an extraction efficiency increase of 1.31 − fold. Additionally, the infrared spectrum, viscosity, conductivity, and polarity of the deep eutectic solvent were measured, and its recycling was investigated. The extraction mechanism was elucidated through a synergistic investigation of extraction kinetics models, molecular dynamics simulations, and intermolecular interaction analysis, revealing that hydrogen bonding is a key driving force in the extraction process. Bioactivity assessments demonstrated significant pharmacological potential of the extract, with potent antioxidant capacity. The crude <em>Cercis glabra</em> flavonoid extract (CCEF) exhibited inhibition rates of 92.74 ± 0.74 %, 41.90 ± 0.90 %, and 20.49 ± 0.31 % against DPPH, ABTS, and PTIO radicals, respectively. Additionally, the extract exhibited significant inhibitory effects against tyrosinase (41.90 ± 0.91 %), α − glucosidase (57.45 ± 0.21 %), and acetylcholinesterase (64.42 ± 0.31 %) at 1 mg/mL. Furthermore, seven flavonoid compounds were isolated from the <em>C. glabra</em> flavonoid extract, and their pharmacological activities were determined, further confirming the biological activity of the extract.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"120 ","pages":"Article 107434"},"PeriodicalIF":8.7,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonically assisted synthesis of Co-Ni bimetallic oxides for simultaneous detection of furazolidone and metronidazole","authors":"Rijia Liu ,&nbsp;Bolin Wu ,&nbsp;Changru Xu ,&nbsp;Chaojun Zhang ,&nbsp;Meng Han ,&nbsp;Meiting Zhao ,&nbsp;Wein-Duo Yang ,&nbsp;Rui Liu","doi":"10.1016/j.ultsonch.2025.107433","DOIUrl":"10.1016/j.ultsonch.2025.107433","url":null,"abstract":"<div><div>This work developed an ultrasonically assisted synthesis of nickel cobaltite (NiCo₂O₄) modified electrode for simultaneous detection of Furazolidone (FRZ) and Metronidazole (MTR) in biological samples. The structural and chemical properties of the as-prepared electrodes were systematically characterized through multiple analytical techniques. The NiCo₂O₄-modified glassy carbon electrode (NiCo₂O₄/GCE) demonstrated exceptional performance with wide linear ranges of 0.005–200 μM for MTR and 0.01–150 μM for FRZ, with remarkably low detection limits of 2.57 nM and 29.13 nM, respectively. The sensor exhibited excellent selectivity against common interferents, good reproducibility, and maintained &gt; 90 % activity after 30 days. NiCo₂O₄/GCE can be used to detect MTR and FRZ in real pharmaceutical and serum samples, achieving excellent recovery rates within the range of 94.0 % to 114.0 %. This work not only presents a superior sensing platform for antibiotic monitoring but also establishes ultrasound-assisted synthesis as an effective strategy for developing advanced bimetallic oxide electrocatalysts.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"120 ","pages":"Article 107433"},"PeriodicalIF":8.7,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drying characteristics and quality enhancement of Moringa oleifera seeds through Ultrasound and Microwave-Assisted germination combined with infrared vacuum drying","authors":"Palwasha Gul ,&nbsp;Jabir Khan ,&nbsp;Yang Li ,&nbsp;Qingyun Li ,&nbsp;Huiyan Zhang ,&nbsp;Kunlun Liu","doi":"10.1016/j.ultsonch.2025.107432","DOIUrl":"10.1016/j.ultsonch.2025.107432","url":null,"abstract":"<div><div><em>Moringa oleifera</em> (MO), is greatly appreciated for its high nutritional profile. Germination is an efficient technique to enhance the quality profile of seeds. This study examined the effects of germination and various pre-treatments on MO seeds. MO seeds were subjected to ultrasound dual-frequency 10 and 20 min (US 10 &amp; US 20), microwave 30 and 60 s (MW 30 &amp; MW 60), followed by 15-day germination at 25 °C in a biochemical incubator and subsequent infrared vacuum drying at 70, 60 and 50 °C. Several mathematical modelling were applied, among which Midilli-Kucuk model showed excellent fit R² ≥ 0.9997, X² ≤ 0.0030, RMSE ≤ 0.0010, and RSS ≤ 0.000, followed by Newton model respectively. The efficiency of the process varied across different treatment conditions, with values ranging from 3.4 % to 10.27 %, indicating significant differences in energy consumption and water removal rates. Overall in the subsequent drying, US 10 at<!--> <!-->60 °C significantly improved quality profile of MO seeds (p ≤ 0.05). Antioxidant potency composite (APCI) of germinated MO seeds showed superior APCI in US 10 dried at 60 °C (97.50 %) than control (56.55 %). The principal component analysis (PCA) revealed a significant correlation matrix, explaining 62.14 % of the total variability in the nutritional and bioactive components of MO seed. GC–MS analysis revealed 50 volatile compounds, categorized into 9 chemical classes with acids being the most abundant. SEM analysis showed that 70 °C, drying caused structural degradation, whereas 60 °C preserved seed microstructure more effectively, revealed pre-treatments and temperature-dependent microstructural alterations. These findings demonstrate the efficacy of pre-treatments assisted germination and moderate-temperature infrared vacuum drying as a viable option for improving the nutritional profile of MO seeds. Importantly, this study did not employ formal optimization techniques such as response surface methodology (RSM), energy cost minimization, full techno-economic and life cycle assessments from an engineering perspective. Instead, it sufficiently explored the drying kinetics and the impact of different pre-treatments on the quality profile of MO seeds.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"120 ","pages":"Article 107432"},"PeriodicalIF":8.7,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144364981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remote biofilm dislodgment using focused acoustic vortex.","authors":"Chih-Hsien Li, Wei-Hao Chao, Ping-Ching Wu, Ching-Hsiang Fan","doi":"10.1016/j.ultsonch.2025.107423","DOIUrl":"10.1016/j.ultsonch.2025.107423","url":null,"abstract":"<p><p>Biofilms constitute a major challenge in treating implant-associated and chronic infections due to their structural resilience and drug resistance, particularly as implant demand rises due to aging populations. Conventional methods are often invasive, complex, and costly, while focused ultrasound (FUS) poses risks related to biocompatibility and tissue damage. Distinguished by its helical phase structure and rotational energy distribution, focused acoustic vortex (FAV) theoretically generates stronger rotational forces and acoustic streaming than FUS under identical acoustic conditions. This study investigates the feasibility of FAV technique for biofilm removal. Biofilms in vitro model were established using Escherichia coli, and a 2-MHz custom-built ultrasound transducer was employed to generate either FAV or FUS. Results indicated that FAV activation generated a centripetal vortical flow with rapid rotation, which was adjustable via acoustic pressure and duty cycle. Conversely, FUS generated solely outward acoustic streaming, exhibiting a flow velocity 43.6 % lower than that of FAV. At 1.75 MPa, implementing a 10 % duty cycle and a 180 s treatment, FAV removed 97 % of the biofilm, whereas FUS removed only 7 %. To achieve a comparable removal rate (95.8 %), FUS required 4 MPa for 10 minutes. Streaming velocity (R² = 0.99) exhibited a strong correlation with biofilm removal, while inertial cavitation (R² = 0.19) exhibited a weak correlation; thus, the former was identified as the primary contributing mechanism. Importantly, FAV treatment resulted in minimal thermal elevation (<5 °C) and no significant reduction in cell viability, demonstrating its biosafety under the applied acoustic parameters. Synergistic tests with antibiotics further suppressed biofilm regrowth for up to 72 h, reducing bacterial concentration by 91 %. Future work will focus on in vivo biofilm models and assessing the safety and efficacy of combined treatments to advance clinical applications.</p>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":" ","pages":"107423"},"PeriodicalIF":8.7,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanistic understanding of corn processing by-products valorization via microbial ultrasound-assisted fermentation: Community succession and metabolic changes","authors":"Shuai Zhang ,&nbsp;Shun Cui ,&nbsp;Qining Li ,&nbsp;Xin Zheng ,&nbsp;Jingsheng Liu","doi":"10.1016/j.ultsonch.2025.107429","DOIUrl":"10.1016/j.ultsonch.2025.107429","url":null,"abstract":"<div><div>The corn gluten meal-corn stalk mixture (CCM) was used as a fermentation substrate composed of two agricultural by-products: corn gluten meal, obtained during wet milling for starch and syrup production, and corn stalk, a lignocellulosic residue left after corn harvest. To facilitate the valorization of agricultural by-products, ultrasound-assisted fermentation was conducted using <em>Aspergillus niger</em> and <em>Limosilactobacillus fermentum</em> at power densities of 50 W/L (F-L) and 100 W/L (F-H), respectively. CCM ultrasound-assisted fermentation led to significant degradation of macromolecules and zein. Compared to the non-ultrasound group, trichloroacetic acid-soluble protein in F-H increased by 6.79-fold, and total amino acids increased by 1.44-fold. Total phenols and flavonoids in F-L and F-H increased, thereby enhancing the antioxidant capacity of CCM. Ultrasound-assisted fermentation primarily increased the abundance of <em>Limosilactobacillus</em>, <em>Pediococcus</em>, <em>Pichia</em>, and <em>Aspergillus</em>, while reducing the abundance of <em>Pantoea</em>, <em>Xanthomonas</em>, <em>Curtobacterium</em>, <em>Staphylococcus</em>, <em>Alternaria</em>, <em>Blumeria</em>, <em>Cladosporium</em>, <em>Fusarium</em>, and <em>Mucor</em>. Environmental acidification drove the microbial community to shift towards more acid-tolerant species. Functional predictions revealed upregulated pathways involved in amino acid and bioactive substance biosynthesis, providing a new perspective on the high-value utilization of CCM.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"120 ","pages":"Article 107429"},"PeriodicalIF":8.7,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonic-assisted soldering of 7075 Al alloy joint using Ni mesh reinforced SAC305 composite solder: microstructure, bonding ratio, and mechanical properties","authors":"Dan Li ,&nbsp;Yong Xiao ,&nbsp;Yu Zhang ,&nbsp;Yu Zhao ,&nbsp;Jian Zhang ,&nbsp;Dan Luo","doi":"10.1016/j.ultsonch.2025.107430","DOIUrl":"10.1016/j.ultsonch.2025.107430","url":null,"abstract":"<div><div>Suppressing solder overflow has significant implications for promoting the application of ultrasonic-assisted soldering. In this work, an innovative strategy of adding metal mesh into Sn-based solder was utilized. 7075 Al alloy joints were ultrasonically soldered with Ni mesh reinforced SAC305 composite solders. The microstructure, bonding ratio, and shear properties of joints were systematically explored. Results showed that solder seams primarily consisted of Ni mesh, SAC305 solder, α-Al phase, Ag₃Al₂ phase, (Ni, Cu)₃Sn₄ phase, Al₃(Ni, Cu)₂ phase, and dispersed fine particles. The bonding interface between Ni mesh and Al substrate could be divided into contact and non-contact regions. A polycrystalline Al₃(Ni, Cu)₂ phase and a Cu-Al-O amorphous layer were formed at the contact regions. The bonding ratio of joints was mainly affected by the cavitation effects within non-contact regions. Adding Ni meshes could enhance the acoustic pressure and accelerate the flow of local solder in the solder seams. The decrease in the bonding ratio was attributed to the excessive solder flow, which induced the formation of defects. Benefiting from the intrinsic strengthening of Ni mesh and metallurgical reaction strengthening, Al/250#Ni-SAC/Al joints exhibited a shear strength of 71.87 MPa.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"120 ","pages":"Article 107430"},"PeriodicalIF":8.7,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An integrated numerical modelling framework for simulation of the multiphysics in sonoprocessing of materials","authors":"Ling Qin ,&nbsp;Kang Xiang ,&nbsp;Lianxia Li ,&nbsp;Iakovos Tzanakis ,&nbsp;Dmitry Eskin ,&nbsp;Jiawei Mi","doi":"10.1016/j.ultsonch.2025.107428","DOIUrl":"10.1016/j.ultsonch.2025.107428","url":null,"abstract":"<div><div>We have designed, developed, and integrated a comprehensive mathematical and numerical modelling framework for simulations of the complex physics and highly dynamic phenomena that occur across different length and time scales in the processes of sonochemistry and sonication of materials. The framework comprises three interconnected sub-models: (1) a bubble oscillation and implosion model, (2) a shock wave emission and propagation model, and (3) a wave–structure interaction (WSI) model. Firstly, we described in detail the governing equations, numerical schemes, boundary and initial conditions used in each sub-model with a particular emphasis on the data mapping methods for numerically linking the three sub-models together. Then, we present a number of simulation cases to demonstrate the power and usefulness of the model. We also did systematic model validation and calibration using the <em>in-situ</em> and real-time collected big X-ray image data. This is the first time such comprehensive and high-fidelity numerical models have been achieved for sonoprocessing of materials. Complementary to the most advanced <em>in-situ</em> and operando experiments, the integrated model is an indispensable modelling tool for computational studies and optimizations of the ultrasound-assisted chemical synthesis and sonoprocessing of materials.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"120 ","pages":"Article 107428"},"PeriodicalIF":8.7,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144289947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}