Ultrasonics Sonochemistry最新文献

{"title":"Synthesis of nanoparticles of feroxyhyte doped with lanthanum by a sonochemical method","authors":"Dolores Reyman,&nbsp;Cristina Díaz-Oliva","doi":"10.1016/j.ultsonch.2025.107363","DOIUrl":"10.1016/j.ultsonch.2025.107363","url":null,"abstract":"<div><div>This work deals with the sonochemical synthesis of colloidal dispersions of magnetic nanoparticles formed by lanthanum-doped iron oxyhydroxides coated with citrate. Our aim is to obtain bimodal contrast agents with magnetic properties that allow their use in both resonance and X-ray techniques.</div><div>For this purpose, three synthesis strategies have been developed using a combination of ultrasound and co-precipitation methods. Three ultrasound frequencies were used in the synthesis: 581, 861 or 1141 kHz. The structural characterization of the prepared materials was carried out by X-ray diffraction (XRD), transmission electron microscopy (TEM), Raman spectroscopy, total reflection X-ray fluorescence (TXRF) and Scanning Electron Microscopy/Energy Dispersive X-ray Spectroscopy (SEM/EDX)</div><div>In the presence of lanthanum, magnetite cannot be formed. Instead, an orange-brown magnetic compound is obtained. Both XRD diffraction patterns and Raman spectra confirmed that the obtained compound is a feroxyhyte containing an amorphous lanthanum compound in its structure. The size of the feroxyhyte nano-discs remained almost constant when the ultrasound frequency was increased. The La/Fe molar ratio of the samples obtained increases when La(OH)₃, which is prepared in the preliminary stages, is added rather than LaCl₃. This procedure makes it possible to control the amount of lanthanum absorbed by the sample by simply varying its initial concentration.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"118 ","pages":"Article 107363"},"PeriodicalIF":8.7,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143899273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonic disorder-induced deposition of TiO2 nanorod arrays and C60 coating on carbon cloth for high-performance supercapacitor electrodes","authors":"Huaxing Li ,&nbsp;Chunyang Ma ,&nbsp;Fafeng Xia ,&nbsp;Zhongmin Xiao","doi":"10.1016/j.ultsonch.2025.107347","DOIUrl":"10.1016/j.ultsonch.2025.107347","url":null,"abstract":"<div><div>To address the growing need for high-performing and stable energy storage devices, optimizing the durability and structure of supercapacitor electrodes is crucial. Traditional electrodes frequently face challenges in achieving an optimal balance between electrochemical capacity and structural stability. This study presents the synthesis of TiO₂/CC@C array electrodes through ultrasonic disorder-induced deposition (UDID), specifically for high-performing supercapacitor applications. The impact of different ultrasonic power levels (50–200 W) on the electrodes’ structural and electrochemical properties was systematically examined. SEM analysis indicated that the sample prepared at 150 W showed an optimal, densely packed array of TiO₂ nanorods with improved surface uniformity, facilitating efficient ion transport. The 150 W TiO₂/CC@C sample displayed a 46.73 m²/g specific surface area and a mean pore diameter of 9.35 nm, contributing to improved charge storage capacity. Raman spectroscopic analysis further confirmed the successful synthesis of the TiO₂/CC@C composite, revealing distinct TiO₂ and carbon-related peaks. Electrochemical measurements showed that this electrode attained a specific capacitance of 687.3F/g at a scan rate equal to 5 mV/s. The system delivered an energy density equal to 158.4 Wh/kg at a power density of 20 W/kg when assembled as an asymmetric supercapacitor (ASC) with AC as the positive electrode. Furthermore, after 10,000 cycles, it maintained 86.3 % of its initial capacitance demonstrating outstanding cycling stability. These findings indicate that optimizing ultrasonic power to 150 W significantly improves both the structural and electrochemical performance of TiO₂/CC@C, making it a promising candidate for advanced supercapacitor applications.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107347"},"PeriodicalIF":8.7,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143855178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound assisted natural deep eutectic solvents based sustainable extraction of Spirulina platensis and orange peel extracts for the development of strawberry-cantaloupe based novel clean-label functional drink","authors":"Kashmala Chaudhary ,&nbsp;Samran Khalid ,&nbsp;Taghrid S. Alomar ,&nbsp;Najla AlMasoud ,&nbsp;Sadia Ansar ,&nbsp;Ahmed Fathy Ghazal ,&nbsp;Abderrahmane Aït-Kaddour ,&nbsp;Rana Muhammad Aadil","doi":"10.1016/j.ultsonch.2025.107357","DOIUrl":"10.1016/j.ultsonch.2025.107357","url":null,"abstract":"<div><div>The consumer demand for sustainable, nutrient-rich, and clean-label beverages is growing rapidly, so there is an urgent need to meet this demand. In response, the present study introduced the new concept of clean-label functional foods and beverages. The objective of the research was to develop novel ready-to-serve clean-label functional drink formulations by blending strawberry and cantaloupe juices (35 % each), with the addition of <em>Spirulina platensis</em> and orange peel extracts as clean-label functional ingredients, either alone or in combination, at concentrations of 2.5 % and 5.0 %, without any chemical additives or preservatives. Ultrasound-assisted extraction under optimized conditions, pulsating mode (10 s on, 5 s off), power 300 W, frequency 25 kHz, extraction time 30 min, and temperature 40 °C, with natural deep eutectic solvent composed of lactic acid and choline chloride (2:1) was used to obtain <em>S. platensis</em> and orange peel extracts. This innovative method achieved the highest extract yield compared to other extraction techniques, making these extracts ideal clean-label functional ingredients due to their highly efficient, sustainable, and eco-friendly extraction process. The formulations were subsequently homogenized via ultrasonication with mild parameters (power 100 W, frequency 25 kHz, time 5 min, temperature 25 °C) to improve the overall stability of the drink. Comprehensive analysis revealed that the T6 formulation, containing 5.0 % <em>S. platensis</em> and 5.0 % orange peel extract, exhibited the most promising results across various parameters, including improved proximate composition, enriched mineral content, elevated bioactive compounds, enhanced antioxidant activity, potent antimicrobial properties, and superior sensory acceptance. By introducing and validating the concept of clean-label functional beverages, this study paves the way for future innovations that align with the evolving demands of health-conscious consumers, and environmental sustainability.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"118 ","pages":"Article 107357"},"PeriodicalIF":8.7,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143858770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of ultrasonic treatment on the microstructure, antioxidant activities and metabolites of camellia bee pollen","authors":"Yanxiang Bi ,&nbsp;Shiye Luo ,&nbsp;Jiabao Ni ,&nbsp;Song Miao ,&nbsp;Zhen Ning ,&nbsp;Zhihao Zhang ,&nbsp;Sijia Xu ,&nbsp;Wenli Tian ,&nbsp;Wenjun Peng ,&nbsp;Xiaoming Fang","doi":"10.1016/j.ultsonch.2025.107359","DOIUrl":"10.1016/j.ultsonch.2025.107359","url":null,"abstract":"<div><div>Ultrasound is an efficient and eco-friendly friendly non-thermal technology for enhancing the extraction of bioactive ingredients from food. This study explored the impact of ultrasound on the microstructure and antioxidant properties of camellia bee pollen. Additionally, the impact of key contributors to antioxidant activity was examined through non-targeted metabolomics analysis. The results showed that ultrasonic exposure progressively degraded the cell walls of bee pollen, resulting in severe collapse of the intine. Notably, this degradation concurrently facilitated the release of polyphenols and flavonoids. The DPPH and ABTS radical scavenging capacity reached the highest after 40 and 60 min of ultrasonic treatment. After 40 min of ultrasonic treatment, the MDA content in camellia bee pollen exhibited a significant rise of 33.47 % compared to the control group, while it further escalated by 57.07 % after 60 min of ultrasonic treatment. Non-targeted metabolomics analysis identified a total of 7 differential metabolites that serve as potential biomarkers for ultrasonic-treated camellia bee pollen. Further analysis of the purine and nucleotide metabolism pathway indicated that the antioxidant defense systems within camellia bee pollen were activated by ultrasonic treatment, leading to a significant enhancement in its antioxidant capacity. These findings establish a solid foundation for the advancement of ultrasound treatment as a novel and green technology to improve the biological activities and qualities of bee pollen.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"118 ","pages":"Article 107359"},"PeriodicalIF":8.7,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143858701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does macroscopic mass transfer affect sonochemical reaction rate in an ultrasonic bath?","authors":"Takuya Yamamoto ,&nbsp;Shinya Okino","doi":"10.1016/j.ultsonch.2025.107361","DOIUrl":"10.1016/j.ultsonch.2025.107361","url":null,"abstract":"<div><div>In the present study, a planar laser induced fluorescence (P-LIF) measurement, reaction rate measurement, the sonochemical luminescence (SCL) observation, and the particle image velocimetry (PIV) measurement were conducted to clarify the effect of macroscopic mass transfer on sonochemical reaction rate in an ultrasonic bath. The concentration distribution was measured by the fluorescence intensity of Rhodamine 6G (Rh6G), which was illuminated by a CW-YAG laser sheet. The concentration of Rh6G decreases first in the high reaction zone measured by the SCL observation, and the resulting low-concentration zone expands to the low reaction zone through macroscopic convective mass transfer, which can be observed as solute plumes. Therefore, it is concluded that the mass transfer rate can slightly affect the chemical reaction rate due to the nonuniform concentration distribution in the early stage of sonochemical reaction. The reaction rate is slightly underestimated due to the spatial variation of the concentration in the early stage of ultrasonic degradation. The effect of macroscopic mass transfer on the sonochemical reaction rate was evaluated by first Damköhler number, which was calculated based on the flow velocity obtained by the PIV measurement and the reaction rate constant obtained by the decomposition experiment. Finally, it could be concluded that the first Damköhler number evaluates the effect of macroscopic mass transfer on the sonochemical reaction rate quantitatively and this dimensionless number can be applied to other ultrasonic bath with different condition.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107361"},"PeriodicalIF":8.7,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mesoscopic modeling the interaction of two attached-wall cavitation bubbles","authors":"Weidong Gan ,&nbsp;Shicheng Li ,&nbsp;Xiaolong He ,&nbsp;Dianguang Ma","doi":"10.1016/j.ultsonch.2025.107358","DOIUrl":"10.1016/j.ultsonch.2025.107358","url":null,"abstract":"<div><div>A hybrid thermal lattice Boltzmann cavitation model based on a nonorthogonal framework is developed to investigate the interaction of two attached-wall cavitation bubbles. The interaction modes are systematically analyzed, with an emphasis on how varying contact angles influence the flow and temperature distributions, as well as the evolution of wall heat flux under strong and weak interaction conditions. Bubbles formed on the hydrophobic surface display increased contact radius and greater curvature radii compared to those on the hydrophilic wall, leading to greater volumes but weaker collapse intensity. The growth rate of the bubble equivalent radius for the weak interaction modes consistently follows the relation <span><math><mrow><mi>U</mi><mo>∝</mo><msqrt><mrow><mn>2</mn><msub><mi>p</mi><mi>∞</mi></msub><mo>/</mo><mn>3</mn><msub><mi>ρ</mi><mi>l</mi></msub></mrow></msqrt></mrow></math></span>. Additionally, bubble coalescence occurs at the interface regions along the hydrophobic surface, altering the final collapse dynamics and resulting in distinct temperature and velocity distributions. Finally, the instantaneous heat flux characteristics are explored. Due to differences in the contact points motion rate and microjet angle with the solid wall, the peak value and number of heat flux peaks vary on walls with different wettability.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107358"},"PeriodicalIF":8.7,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A vortex-based hydrodynamic cavitation manufacturing platform to generate albumin microbubbles for delivery of chemotherapies to cancerous tumours","authors":"Promita Bhattacharjee ,&nbsp;Abhijeet H. Thaker ,&nbsp;Pratik Kumar Patel ,&nbsp;Vivek V. Ranade ,&nbsp;Sarah P. Hudson","doi":"10.1016/j.ultsonch.2025.107350","DOIUrl":"10.1016/j.ultsonch.2025.107350","url":null,"abstract":"<div><div>A novel approach was developed to create stable protein-based microbubbles using a vortex-driven hydrodynamic cavitation device. Such microbubbles, tiny gas-filled spheres, combined with ultrasound, can enhance drug uptake leading to inhibition of cancerous cell growth, boosting the effectiveness of anti-cancer drug molecules. The optimal conditions for the fabrication of stable bovine serum albumin (BSA) microbubbles were found to be a 15 wt% bovine serum albumin (BSA) solution at 60 °C with a pH of 6 and an ionic strength of 1.0 M. This resulted in stable BSA microbubbles with an approximate diameter of 7 μm. Curcumin-encapsulated BSA microbubbles (CBMs, 63 ± 1 μM curcumin per 10¹⁰ microbubbles) were created using these optimised fabrication parameters as a model system for delivering chemotherapeutic agents. The maximum percentage of curcumin release from the CBMs into phosphate buffered saline with sonication (85 %) was significantly greater than without sonication (24 %). These microbubbles were then tested to assess their effectiveness in delivering curcumin to triple-negative breast cancer cells (MDAMB-231) using a cell-to-MB ratio of 1:100, an ultrasound intensity of 0.5 W/cm², and an ultrasound exposure time of 10 s to maximise uptake. Kinetic studies demonstrated a significant enhancement in the uptake of curcumin by MDAMB-231 cells when encapsulated into the microbubbles with ultrasound application. A substantial reduction in cellular proliferation was observed in both 2D cell culture and 3D tumour spheroid models when MDAMB-231 cells were exposed to microbubbles loaded with curcumin and ultrasound was applied. The vortex-based hydrodynamic cavitation device successfully generated curcumin loaded microbubbles with a long shelf life (120 days at 4 °C), mild preparation conditions, and enhanced uptake into cancerous tumour spheroid models. This data demonstrates the potential of this device for the commercial manufacture of drug loaded microbubble-based delivery systems.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107350"},"PeriodicalIF":8.7,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143852347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of mechanical-loss property of 3D printing metal and its application to ultrasonic transducers as vibrating bodies","authors":"Lipeng Wang ,&nbsp;Ranxu Zhang ,&nbsp;Jiang Wu ,&nbsp;Chengqi Pan ,&nbsp;Xiaoming Yue ,&nbsp;Qiang Zhang ,&nbsp;Yibin Li","doi":"10.1016/j.ultsonch.2025.107356","DOIUrl":"10.1016/j.ultsonch.2025.107356","url":null,"abstract":"<div><div>As miniaturized ultrasonic transducers with sophisticated structure have become increasingly demanded, the vibrating bodies made by conventional metals face the problem of fabricating difficulty and high expenses. The 3D printing metals are prospective materials for their flexibility in forming complicated configurations, but their mechanical-loss properties need clarification as they greatly affect the vibration properties. As a pilot trail, first, an approach to measure the attention coefficients according to the distributions of the vibration velocity and the phase was developed to evaluate their dependence on the strain and the frequency. Then, an aluminum alloy via 3D printing (AlSi10Mg) was employed as the vibrating bodies to form the ultrasonic transducers, whose performance, e.g., vibration properties, temperature rise, and sound pressure level (SPL) in water, was assessed and compared with conventional aluminum alloy (7075). As typical results, AlSi10Mg’s damping coefficient is 1.16 times that of 7075 at 33 kHz frequency; this implies the 3D printing process does not deteriorate the aluminum alloy’s mechanical-loss property. Meanwhile, AlSi10Mg’s damping coefficient reaches 2.19 × 10^-4 at the laser power of 350 W, relatively small compared to the values corresponding to other laser powers; this indicates the capability to reduce the mechanical loss by adjusting the parameters during 3D printing possesses. Moreover, the maximum vibration velocity and the SPL of the AlSi10Mg transducer are 1.13 and 1.11 times those of the 7075 transducer that has the same configuration and operates in the same vibration modes. This study enriches the candidate materials as the vibrating bodies of ultrasonic transducers, which potentially meet the demands in wider ultrasonic application fields.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107356"},"PeriodicalIF":8.7,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143839142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-activated piezoelectric biomaterials for cartilage regeneration","authors":"Yangchen Wei ,&nbsp;Zhengyang Li ,&nbsp;Tianjing Yu ,&nbsp;Yan Chen ,&nbsp;Qinglai Yang ,&nbsp;Kaikai Wen ,&nbsp;Junlin Liao ,&nbsp;Linlin Li","doi":"10.1016/j.ultsonch.2025.107353","DOIUrl":"10.1016/j.ultsonch.2025.107353","url":null,"abstract":"<div><div>Due to the low density of chondrocytes and limited ability to repair damaged extracellular matrix (ECM) in cartilage, many patients with congenital or acquired craniofacial trauma require filler graft materials to support facial structure, restore function, improve self-confidence, and regain socialization. Ultrasound has the capacity to stimulate piezoelectric materials, converting mechanical energy into electrical signals that can regulate the metabolism, proliferation, and differentiation of chondrocytes. This unique property has sparked growing interest in using piezoelectric biomaterials in regenerative medicine. In this review, we first explain the principle behind ultrasound-activated piezoelectric materials and how they generate piezopotential. We then review studies demonstrating how this bioelectricity promotes chondrocyte regeneration, stimulates the secretion of key extracellular components and supports cartilage regeneration by activating relevant signaling pathways. Next, we discuss the properties, synthesis, and modification strategies of various piezoelectric biomaterials. We further discuss recent progresses in the development of ultrasound-activated piezoelectric biomaterials specifically designed for cartilage regeneration. Lastly, we discuss future research challenges facing this technology, ultrasound-activated piezoelectric materials for cartilage regeneration engineering. While the technology holds great promise, certain obstacles remain, including issues related to material stability, precise control over ultrasound parameters, and the integration of these systems into clinical settings. The combination of ultrasound-activated piezoelectric technology with other emerging fields, such as Artificial Intelligence (AI) and cartilage organoid chips, may open new frontiers in regenerative medicine. We hope this review encourages further exploration of ultrasound-activated strategies for piezoelectric materials and their future applications in regenerative medicines.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107353"},"PeriodicalIF":8.7,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143839144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of ultrasound-induced structural modifications on the emulsifying properties of Tenebrio molitor proteins","authors":"Yun Jae Jang ,&nbsp;Hyeong Do Kim ,&nbsp;Yu Ji Ye ,&nbsp;Ming Kong ,&nbsp;Woo Su Lim ,&nbsp;Min Hyeock Lee","doi":"10.1016/j.ultsonch.2025.107354","DOIUrl":"10.1016/j.ultsonch.2025.107354","url":null,"abstract":"<div><div>Ultrasonication has emerged as a promising technique for modifying physicochemical properties of proteins, enhancing their functionality in food applications. This study evaluated the effects of ultrasonic treatment on the structural and functional properties of mealworm-derived proteins (MPs) and their potential as emulsifiers. Dynamic light scattering revealed a significant reduction in MP particle size from 3464.3 nm (untreated) to 115.5 nm (30 min sonication), along with increased zeta potential, indicating improved colloidal stability. Sonication enhanced oil-holding capacity and solubility, suggesting improved interfacial adsorption and emulsification. Circular dichroism and FT-IR spectroscopy confirmed structural modifications, including increased α-helix content and enhanced hydrogen bonding interactions. Free sulfhydryl content and surface hydrophobicity analyses indicated ultrasound-induced unfolding, exposing functional groups that contribute to emulsifying properties. Sonicated MPs demonstrated superior emulsion stability under varying temperature, pH, and ionic conditions. Furthermore, digestibility analysis showed improved gastric digestion (72.7 % to 82.8 %) and enhanced lipid digestion in the small intestine (36.2 % to 47.9 %), suggesting greater bioavailability. These physicochemical modifications highlight the feasibility of using sonicated MP as natural emulsifiers with enhanced functionality. This study underscores their potential in food formulations, particularly for nutritionally fortified emulsions, contributing to sustainable and functional food ingredient development.</div></div>","PeriodicalId":442,"journal":{"name":"Ultrasonics Sonochemistry","volume":"117 ","pages":"Article 107354"},"PeriodicalIF":8.7,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143826030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}