Perinatology and reproductology: from research to practice最新文献

{"title":"Tactic of prognostication of adhesive process after time-urgen gynaecological operations","authors":"V. Terekhov","doi":"10.52705/2788-6190-2021-4-8","DOIUrl":"https://doi.org/10.52705/2788-6190-2021-4-8","url":null,"abstract":"The objective: study of dependence of expressed of adhesive process for gynaecological patients taking into account an amount and volume of previous operations.\u0000Materials and methods. For the decision of the put purpose inspected and conducted surgical treatment laparoscopic access for 304 patients which carried before operative interferences on the organs of abdominal region and small pelvis. All patients were up-diffused on 3 groups depending on an amount and character of the carried operations. a 1 group (n=159) was made by patients with one чревосечением in anamnesis after gynaecological operations. 2 a group (n=99) is women with two чревосечениями in anamnesis. Gynaecological, surgical interferences or their combinations took place in this group. Patients (n=46) which have in anamnesis 3 and more чревосечений (n=30), and also women (n=16) which carried operative interferences concerning the poured out festering peritonitis, entered in 3 groups, intestinal impassable and perforated gastric ulcers.\u0000Results. Operative interferences are carried by an important factor which results in formation of joints in to the small pelvis. Shown of спаечного process in small to the pelvis had straight proportional dependence on the amount of чревосечений. Among all patients which had in anamnesis a conservative myomectomy in combination with a caesarian section or hysterectomy,\u0000the adhesive process of organs of small pelvis appeared most expressed.\u0000Conclusion. The factors leading to formation of solderings in a small basin, the transferred operative interventions are. The risk of development and expressiveness of postoperative unions are in direct dependence on quantity laparotomy in the anamnesis. Forecasting the instructions on two and more gynecologic interventions, in a greater degree radical operations on a uterus\u0000are adverse. The received results are necessary for using by tactics working out laparocopical treatments of gynecologic patients.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128220589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Features of pathogeny of anaemia of pregnant with violations in a pubertal period","authors":"Orysia Kovalyshin","doi":"10.52705/2788-6190-2021-4-3","DOIUrl":"https://doi.org/10.52705/2788-6190-2021-4-3","url":null,"abstract":"The objective: study of role of whey ferritin in pathogeny of anaemic syndrome for expectant mothers with violations in a pubertal period.\u0000Materials and methods. For the decision of the put purpose in research were included 335 pregnant. All patients parted on two categories: a basic group is 275 women which suffered an anaemic syndrome in I, II and the III trimesters of pregnancy. They were up-diffused on a І group – 185 women, sufferings iron-scarce anaemia in I, II and the III trimesters pregnancies at which the sharp are not fixed or chronic infectious-inflammatory diseases, both to and in the period of the real pregnancy. Anaemia for such women we de bene esse designated as actual iron-scarce anaemia and group II – 90 women with anaemia in the III trimester of pregnancy which developed on a background sharp or chronic infectious-inflammatory pathology. Anaemic syndrome for such patients we de bene esse designated as anaemia of inflammatory diseases. A control group was made by 60 women with the physiology flow of pregnancy and normal indexes of conntrration haemoglobin, numbers of red corpuscles in peripheral blood and exchange of iron, at which chronic infectious and autoimmune diseases are not fixed in anamnesis.\u0000Results. Concentration of haemoglobin in the I trimester for patients with actual iron deficient anaemia which developed in the III trimester, there was authentically higher, than for the patients of control group: 119,8±1,9 g/l against 118,8±2,7 g/l accordingly. Opposite, the concentration of whey ferritin in a control group in all trimesters appeared for certain higher, than for pregnant with anaemia in the different terms of gestation. It confirms that at prognostication of risk of development of anaemia more correct is oriented not on the initial level of haemoglobin, but on the concentration of whey ferritin. The coefficient of linear correlation of the investigated indexes makes in the I trimester of pregnancy +0,63, in the II trimester +0,79, and in trimester +0,77. Essence of logarithmic dependence consists in that at the higher values of whey ferritin haemoglobin goes down not so substantially, as it is marked at the low levels of whey ferritin.\u0000Conclusion. The results of the conducted researches testify to the substantial role of whey ferritin in pathogeny of anaemic syndrome for expectant mothers in all trimesters of gestation. The set features of pathogeny of anaemic syndrome must be taken into account at development of complex of diagnostic and treatment-and-prophylactic measures.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123983822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical analysis of somatic and reproductive anamnesis of pregnant women with sexually transmitted infections in the case history","authors":"O. Krotik","doi":"10.52705/2788-6190-2021-4-4","DOIUrl":"https://doi.org/10.52705/2788-6190-2021-4-4","url":null,"abstract":"The objective: to conduct a clinical and statistical analysis of somatic and reproductive anamnesis of pregnant women with sexually transmitted infections in the case history.\u0000Materials and methods. Clinical and statistical analysis of somatic and reproductive anamnesis of 100 pregnant women with sexually transmitted infections in the case history, who were randomly divided into two groups: I (main) group – 50 pregnant women who were subject to pregravid training, obstetric and perinatal support and delivery according to the medical and organizational algorithms, prognostic methods and medical-preventive activities developed by us; Group II – 50 pregnant women who received conventional prognostic and medical-preventive activities and Group III (control) – 30 practically healthy pregnant women with a successful reproductive history and uncomplicated course of this pregnancy. Data processing was performed using StatSoft Statistica 8.0 software package.\u0000Results. The main risk factors of obstetric and perinatal complications for the women under investigation, with sexually transmitted infections (STIs) in the case history, are: the presence of a high infectious index in the anamnesis (76.0% and 72.0%), chronic and acute inflammatory processes of the urinary tract system (48.0% and 40.0%), STIs before pregnancy (32.0% and 28.0%), as well as reproductive losses of infectious origin (21.0% and 28.0%): miscarriages, fetal growth retardation and placental dysfunction, ante- and intranatal fetal death in the anamnesis. The conducted clinical and statistical analysis based on the studied indicators did not reveal a significant difference between the women of the main group and the control group, which enables us to compare them in a further study.\u0000Conclusions. When comparing the data obtained after analysis of the premorbid background, somatic and reproductive anamnesis of pregnant women with sexually transmitted infections in the case history, significant differences between the main and the control group were not found, which allows us to compare them in a further study.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133732499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Features of infertility for women with different thyroid violations","authors":"Dzhanetti Beraya","doi":"10.52705/2788-6190-2021-4-9","DOIUrl":"https://doi.org/10.52705/2788-6190-2021-4-9","url":null,"abstract":"The objective: study of frequency and structure of thyroid violations for women with infertility.\u0000Materials and methods. For the performance of the put goal the screening estimation of pathology of thyroid was conducted for 298 women with infertility (basic group) and at 50 fertile of women which appealed to the clinic for the selection of method of contraception (control group). The inspection of patients with infertility was conducted in accordance with the generally accepted\u0000diagnostic algorithm, including endoscopic methods, and treatment – depending on found out reasons of infertility\u0000Results. Leading place in the structure of reasons of infertility for women with autoimmune thyroiditis occupied outward genital endometriosis (34,4%), for women with found out a thyroprivia is an endocrine factor of infertility (syndrome of polycystic ovaries) – 29,8%, for patients with the compensated thyroprivia is outward genital endometriosis (26,6%), for women with a euthyroid\u0000goitre and for patients without pathology of thyroid is a pipe-peritoneal factor (33,3% and 39,8% accordingly). For patients with autoimmune thyropathy high-frequency of unmaturing of pregnancy is characteristic – at 2–2,4 time which exceeds analogical indexes in a control group.\u0000Conclusion. For patients with infertility prevalence of thyroid pathology at 3,8 time higher by comparison to fertile women (48% and 12,5% accordingly). In the structure of pathology of thyroid the transmitter of antibodies prevails to thyroperoxidase in combination with the ultrasonic signs of autoimmune thyroiditis (24% and 8,7% accordingly); subclinical thyroprivia as a result of autoimmune thyroiditis (8,6% and 2,5% accordingly); euthyroid goitre (7,8% and 2,5% accordingly). The results of questionnaire, conducted for women with infertility, showed the low diagnostic value of clinical симптоматики of thyroprivia by comparison to laboratory diagnostics in verification of this diagnosis. A sensitiveness of symptoms was low and hesitated from 16,1% to 27,8%, while specificity of symptoms was considerable and varied from 85,1% to 94,5%.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122357059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Features of gestation and deliveries of women with the first medicalabortion in anamnesis","authors":"Serhii Baksheev","doi":"10.52705/2788-6190-2021-4-1","DOIUrl":"https://doi.org/10.52705/2788-6190-2021-4-1","url":null,"abstract":"The objective: study of obstetric and perinatal results of delivery of women with the first medical abortion in anamnesis.\u0000Materials and methods. For the performance of the put goal 119 women are plugged in research. In a basic group 67 entered repeatedly pregnant primiparous of women which cut the first pregnancy short medical abortion in the first trimester. The group of comparison was made 52 primary pregnant women without the burdened obstetric anamnesis. A basic group is subdivided\u0000into two sub-groups: The I sub-group is women (23) which had complication after breaking of the first pregnancy medical abortion; The II sub-group is women (44) which did not have complication after medical abortion. On every postpartum woman the specially developed questionnaire was filled with the results of clinical and functional and laboratory methods of researches.\u0000Results. Most and groups of comparison patients of basic got up on an account in womanish consultation to 12 weeks of pregnancy (83,0% and 72,8%). The basic variants of gestational complications is a threat of breaking to pregnancy, gestational anaemia, preeclampsia and placenta disfunction. Pregnancy made off births through natural family ways in 80,7% patients basic and at a 92,2% group of comparison. Caesarian section it is done at 19,3% and 7,8% women respectively, including at prematurely born pregnancy – in 0,7% (35 weeks) and in 1,9% (32 and 35 weeks). Frequency of premature births made in a basic group – 5,2% and in the group of comparison – 2,9%. Most number of operations caesar sections in a basic group (53,9%) are done in the planned order, in the group of comparison (75,0%) – in a time-urgent order. Among certificates for an operation caesar sections in more than in a that and other group (57,7% and 75,0%) extragenital diseases and complications of pregnancy prevailed the half of supervisions. In a basic group for 67 women pregnancy made off birth 67 living new-born, in the group of comparison for 103 women gave birth 103 living new-born.\u0000Conclusions. The results of the conducted researches testify to the substantial difference of features of flow of pregnancy and births for women, having medical abortion in anamnesis and not having the burdened anamnesis. It is possible to assert that row of complications, developing during pregnancy for the women of basic group related to the before carried operation of medical\u0000abortion (threat of breaking to pregnancy, anomalies of childbirth, dense attachment of placenta, intrauterine infecting of fetus).\u0000The got results specify on the necessity of improvement of algorithm of conduct of pregnancy and births for women with the first medical abortion in anamnesis.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132513187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age-related aspects of efficiency of auxiliary genesial technologies at the combined forms of infertility","authors":"O. Berestovoy","doi":"10.52705/2788-6190-2021-4-10","DOIUrl":"https://doi.org/10.52705/2788-6190-2021-4-10","url":null,"abstract":"The objective: to study the role of age of patients in the estimation of efficiency of auxiliary genesial technologies at the combined forms of infertility.\u0000Materials and methods. For the decision of the put purpose we inspected 70 women of genesial age, which made the followings groups: basic (n=30), comparisons (n=30) and control (n=10). To the complex of the conducted researches were included clinical, echographic, endocrinology, morphological, statistical and immunological.\u0000Results. With the increase of age of patients the amount of growings follicles goes down appropriately; ovaries of oocyte got during puncture, including mature. One of mechanisms of violation of follicogenesis and oogenesis is a change to the cytokine adjusting of these processes. With the increase of age of patients there is an increase of content in the follicle liquid of ovaries\u0000of proinflammatory cytokines. Stimulation of ovaries of гонадотропинами is accompanied by growth of follicles, recruiting and\u0000activating of immunocompetency cages with induction of anti-inflammatory, pro inflammatory cytokines and chemokines. A negative role high concentrations can play in blood of estradiol, and also pharmacological preparations which are used during stimulation of ovaries (гонадотропины, agonists and antagonists of gonadotropin-releasing-hormone), and also age of patients. Conclusions. To the informing clinical and anamnestic and hormonal factors which determine the result of cycle of auxiliary genesial technologies for the patients of genesial age with the combined forms of infertility, take: age of patient, index of mass of body, presence of pipe-peritoneal factor of infertility, level free to testosterone in blood, table of contents of progesterone in blood on 20–22 days of menstrual cycle, and also determination in the follicle liquid of ovaries of cytokines. We are rotin the role of age of patients in the estimation of efficiency of auxiliary genesial technologies.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"29 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113962052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early neonatal period of newborns from mothers with sexually transmitted infections in the case history","authors":"O. Krotik","doi":"10.52705/2788-6190-2021-3-2","DOIUrl":"https://doi.org/10.52705/2788-6190-2021-3-2","url":null,"abstract":"The objective: to analyze the perinatal consequences of childbirth and the early neonatal period of the newborns from mothers with sexually transmitted infections in the case history.\u0000Materials and methods. In order to meet the objective, we examined 80 pregnant women on the basis of the Kyiv City Center of Reproductive and Perinatal Medicine (the clinical base of the Department of Obstetrics, Gynecology and Reproductology of Shupyk National Healthcare University of Ukraine) for the period of 2020–2021. There were two groups: group I – 50 pregnant women with STIs in the case history and group II – a control group – 30 practically healthy pregnant women with a successful reproductive history and uncomplicated course of the present pregnancy. Clinical and statistical analysis of perinatal consequences of childbirth and early neonatal period in newborns from these women was conducted.\u0000Results. The analysis of perinatal consequences of childbirth from women with sexually transmitted infections in the case history showed a high frequency of intranatal asphyxia of varying severity – 19 children (38.0%), severe – 2 children (4.0%). The early neonatal period disease incidence of infants born from the women in this group is 38 (38.0%; p<0.05) cases against 13.3% in the control group. The frequency of detection of fetal growth retardation syndrome in women patients of group I significantly increased compared to women from the control group - up to 10.0% (p<0.05 by criterion χ2). The fetal growth retardation syndrome occurred in women of group I, due to the placenta dysfunction, which was caused by the primary deterioration of uteroplacental hemodynamics and microthrombosis in the placenta. At the same time, early FGR (up to 32 weeks) was detected in women of group I – 80.0% of cases. It can be assumed that the development of FGR syndrome coincides with the manifestation of the underlying sexually transmitted disease during gestation. Manifestations of intrauterine infection were observed in newborns from women from group I in 18.0% of cases, which was statistically significant compared to the control (p<0.05 by criterion χ2). Among this category of newborns, inflammatory processes of the skin (44.4%), urinary tract infections (33.3%), and pneumonia (22.2%) were most of ten observed.\u0000Conclusions. The study confirms and suggests that the presence sexually transmitted infection in the case history adversely affects perinatal outcomes. This had a negative effect on the newborn with the realization in the form of asphyxia, decreased weight growth, CNS damage, conjugative jaundice, intrauterine infection and its implementation in the early neonatal period. Ensuring quality care for this category of newborns requires special attention of neonatologists to predict neonatal complications of intrauterine infection.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129870139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbiotes of the vagina, cervical canal and uterine cavity in chronic endometritis","authors":"A. Haiduk","doi":"10.52705/2788-6190-2021-3-7","DOIUrl":"https://doi.org/10.52705/2788-6190-2021-3-7","url":null,"abstract":"The objective: to determine the profile of vaginal, cervical and uterine microbiota in chronic endometritis in patients with failed ART attempts in history.\u0000Materials and method. A prospective study and clinical laboratory analysis of vaginal microbiocenosis, cervical canal and uterine cavity in women with chronic endometrite in a history on the basis of MC LLC «ISIDA - IVF», in the period from 2020 to 2021 was carried out. The group consisted of 55 women of reproductive age with chronic endometritis and repeated failed ART attempts, and 40 women of reproductive age without fertility impairment who formed the control group. Amount of research – Vaginal Secretion PH, Vaginal Microbial Estimation of Pap Smear Microscopy, Polymerase Chain Reaction Study (PCR), Culture Study of Vaginal Secretions, Study of microflora of the cervical channel and bioptat of endometrium.\u0000Results. In women with infertility, against the background of chronic endometritis in history, as a result of bacterial sowing from the uterine cavity, the predominance of mixed bacterial flora, which is represented by various associations of opportunistic and pathogenic micro-organisms, has been detected. Chronic inflammatory endometry is caused by a persistent viral bacterial\u0000infection in the uterine cavity, which differs in species composition from the microflora of the lower genital tract.\u0000Conclusions. The characteristic feature of the vaginal flora in chronic endometritis is a high level of dissbiotic changes, combined with high values of the notional pathogenic flora. The microbiotopes of the cervical channel and endometrium in the inflammatory processes of endometry are characterized by the predominance of obligatory-anaerobic micro-organisms in the form of associations with viral infection much more than twice as frequently detected in endocervix as compared to endometrium.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"118 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116401225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Features of condition of hemodynamic and homeostasis at acute gynecologic diseases","authors":"Volodymyr Terehov","doi":"10.52705/2788-6190-2021-3-13","DOIUrl":"https://doi.org/10.52705/2788-6190-2021-3-13","url":null,"abstract":"In recent years, there has been a significant increase in urgent conditions in gynecology. The use of inadequate and sometimes unjustified surgical interventions due to the peculiarities of the clinical course of the disease, the difficulties of early diagnosis, uncertainty of treatment tactics can lead to complications and even death of the patient. Therefore, improving early diagnosis and\u0000emergency care is one of the priorities of modern medicine.\u0000The objective: to improve the early diagnosis and comprehensive treatment of acute gynecological conditions to study the structure and features of urgent gynecological diseases in modern conditions; analyze indicators of hemodynamics and homeostasis (including immune) to reduce possible complications in patients with acute gynecological diseases.\u0000Materials and methods. A 5-year retrospective clinical and anamnestic analysis of 1261 case histories of patients with various acute gynecological diseases, the most common of which are acute pelvic inflammatory disease (PID), uterine and intraperitoneal bleeding, impaired blood supply to internal tumors. Patients in the comparative groups were comparable in age and course\u0000of the pathological process in the genitals.\u0000Results. The study found that among acute gynecological diseases dominated by acute PID (41,4%), uterine bleeding (31,6%), intra-abdominal bleeding (20,8%), impaired blood supply to tumors of the internal genitalia (6,2%), and in the last two groups the incidence increased. The age of patients varied significantly depending on the type of pathology. Clinical manifestations of acute\u0000PID and impaired blood supply to tumors of the internal genitalia in most cases were characterized by a predominance of pain and intoxication syndromes. Intra-abdominal and uterine bleeding was dominated by symptoms associated with hemodynamic disturbances and posthemorrhagic anemia. A high frequency of anemia of toxic genesis was observed in patients with acute PID and impaired blood supply to tumors of the internal genitalia.\u0000Conclusion. In modern conditions, the percentage of patients in need of emergency care is increasing, mainly due to an increase in the number of patients with intraperitoneal bleeding and impaired blood supply to tumors of the uterus and ovaries. The course of urgent gynecological diseases is accompanied by a violation of the adaptive-regulatory mechanisms of detoxification, indicators of homeostasis, immune system, hemodynamics, acid-base state of the blood. Given the clinical picture of the disease and the\u0000established diagnosis, it is necessary to develop individual management tactics for each patient.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"1964 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129926003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical and social aspects of women with menstrual dysfunction in puberty","authors":"O. Kovalishin","doi":"10.52705/2788-6190-2021-3-10","DOIUrl":"https://doi.org/10.52705/2788-6190-2021-3-10","url":null,"abstract":"The reproductive system is exposed to various adverse factors and harmful effects at all stages of the functioning of the body. Against the background of a decrease in the level of reproductive female health in recent years, there is a clear tendency towards an increase in the number of patients with pathology of the puberty period. The low level of somatic and reproductive health before pregnancy causes a high frequency of complicated births, which leads to a deterioration in the development of subsequent generations.\u0000The objective. Based on clinical and anamnestic data, laboratory and instrumental methods of research, analysis of risk factors, clinical presentation, treatment effectiveness and clinical observation, to give a clinical description of women who had menstrual dysfunction in the pubertal period.\u0000Materials and methods. According to the nature of the violations, the main group of women (n=210) who had a pathology of menstrual function in the puberty period was divided into 3 subgroups (n=70): the first – women with primary oligomenorrhea and timely average population menarche, the second – with a late age menarche, the third – with puberty bleeding. The control\u0000group included women (n=70) with the correct rhythm of menstruation in puberty.\u0000Results. During a clinical prospective study, the social status of women with impaired reproductive function in the puberty was analyzed, the frequency and structure of existing concomitant somatic diseases, the duration of the menstrual cycle, the nature of diseases of the female genital organs; an assessment of the complex treatment of the revealed violations was made, which allowed\u0000to obtain a favorable reproductive prognosis. Most of the women examined (53.3%) planned a pregnancy, which occurred in 75.9% of those planning.\u0000Conclusion. A study of the clinical and anamnestic analysis of the reproductive function of women with menstrual irregularities in the puberty period will increase the effectiveness of the treatment of identified disorders and develop algorithms for the management of such women during planning and during pregnancy.","PeriodicalId":419861,"journal":{"name":"Perinatology and reproductology: from research to practice","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129309261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}