Current Urology最新文献

{"title":"Predictors of stone-free rate after a single-session extracorporeal shockwave lithotripsy for a single kidney stone measuring 10 to 20 mm: A private center experience.","authors":"Amr A Faddan,&nbsp;Osama Najieb,&nbsp;Rabea A Gadelkareem","doi":"10.1097/CU9.0000000000000152","DOIUrl":"https://doi.org/10.1097/CU9.0000000000000152","url":null,"abstract":"<p><strong>Background: </strong>Despite the continuous update of guidelines for the management of kidney stones, the ability to predict a successful response to extracorporeal shockwave lithotripsy (SWL) remains a topic of research. This is due to the need to refine the decision making in the context of technological advancements and current pandemics. This study aimed to determine the predictors of stone-free rate (SFR) after single-session SWL in adult patients with a single kidney stone 10 to 20 mm in diameter.</p><p><strong>Materials and methods: </strong>A retrospective review of the records of patients with a single kidney stone 10 to 20 mm in diameter was performed at a private SWL center from December 2019 to February 2021. Univariate and multivariate analyses were performed for stone- and patient-related factors, using the Student <i>t</i> and Mann-Whitney <i>U</i> tests for the quantitative variables and the Fisher exact and Pearson correlation tests for the qualitative variables.</p><p><strong>Results: </strong>A total of 138 patients were eligible for this study, including 92 men and 46 women. The mean age was 38.6 ± 12.4 years, and the mean body mass index (BMI) was 25.9 ± 3.4 kg/m². Four weeks after SWL, 120 patients (87%) were free of stones, and 18 (13%) needed further treatment. Univariate analyses showed that SFR was negatively correlated with increased BMI (<i>p</i> = 0.0001), maximum stone length (<i>p</i> = 0.0001), transverse diameter of the stone (<i>p</i> = 0.0001), number of shocks per session (<i>p</i> = 0.052), and Hounsfield unit (HU) (<i>p</i> = 0.0001). Multivariate analysis revealed that HU (<i>p</i> = 0.009), maximum stone length (<i>p</i> = 0.01), BMI (<i>p</i> = 0.000), and presence of double-J stent (<i>p</i> = 0.034) were independent risk factors for failure of single-session SWL in the treatment of kidney stones 10 to 20 mm in diameter. The estimated average cost per case was USD 450.5.</p><p><strong>Conclusions: </strong>Increased HU, maximum stone length, BMI, and presence of double-J stents were independent risk factors for low SFR after single-session SWL for a kidney stone 10 to 20 mm in diameter. The cost of SWL remains an advantage in the private sector.</p>","PeriodicalId":39147,"journal":{"name":"Current Urology","volume":"17 1","pages":"30-35"},"PeriodicalIF":1.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9a/7d/curr-urol-17-30.PMC10487291.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10224048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dysregulation and implications of N6-methyladenosine modification in renal cell carcinoma.","authors":"Yaohai Wu,&nbsp;Shiqiang Zhang,&nbsp;Chujie Chen,&nbsp;Jun Pang","doi":"10.1097/CU9.0000000000000135","DOIUrl":"https://doi.org/10.1097/CU9.0000000000000135","url":null,"abstract":"<p><p>Increasing evidence indicates that N⁶-methyladenosine (m⁶A) methylation modification serves important functions in biological metabolism. Dysregulation of m⁶A regulators is related to the progression of different malignancies, including renal cell carcinoma (RCC). Recent studies have reported preliminary findings on the influence of m⁶A regulator dysregulation on RCC tumorigenesis and development. However, no comprehensive review that integrates and analyzes the roles of m⁶A modification in RCC has been published to date. In this review, we focus on the dysregulation of m⁶A regulators as it relates to RCC tumorigenesis and development, as well as possible applications of m⁶A modification in RCC diagnosis and therapeutics.</p>","PeriodicalId":39147,"journal":{"name":"Current Urology","volume":"17 1","pages":"45-51"},"PeriodicalIF":1.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/51/76/curr-urol-17-45.PMC10487297.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10221805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current laser therapy options for endoscopic treatment of upper tract urothelial carcinoma.","authors":"Benjamin W Zollinger,&nbsp;Ezra J Shoen,&nbsp;Charles F Gresham,&nbsp;Michael J Whalen","doi":"10.1097/CU9.0000000000000158","DOIUrl":"https://doi.org/10.1097/CU9.0000000000000158","url":null,"abstract":"<p><p>Endoscopic management via retrograde ureteroscopic laser ablation of upper tract urothelial carcinoma (UTUC) has become the preferred treatment modality for low-risk tumors. The most popular ablative lasers over the past 15-20 years have been the holmium:yttrium-aluminum-garnet (Ho:YAG) and neodymium (Nd:YAG) lasers, but recently the thulium (Th:YAG) laser has emerged as a potential alternative. This review compares the mechanism of action, physiological properties and effects, and oncologic outcomes of Ho:YAG/Nd:YAG lasers versus the Th:YAG laser for UTUC treatment. Potential advantages of the Th:YAG laser over existing technologies are outlined, followed by a discussion of emerging laser technologies in UTUC management.</p>","PeriodicalId":39147,"journal":{"name":"Current Urology","volume":"17 1","pages":"62-67"},"PeriodicalIF":1.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/96/92/curr-urol-17-62.PMC10487284.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10224051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new era: Comparing wired to wireless endoscopy","authors":"Di Niu, Cheng Yang, Chao Liang","doi":"10.1097/cu9.0000000000000176","DOIUrl":"https://doi.org/10.1097/cu9.0000000000000176","url":null,"abstract":"","PeriodicalId":39147,"journal":{"name":"Current Urology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43432297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ability of clock drawing errors on Mini-Cog test to predict development of delirium after major urological cancer surgery","authors":"S. Yajima, Y. Nakanishi, S. Matsumoto, N. Okubo, K. Tanabe, M. Kataoka, H. Masuda","doi":"10.1097/cu9.0000000000000177","DOIUrl":"https://doi.org/10.1097/cu9.0000000000000177","url":null,"abstract":"","PeriodicalId":39147,"journal":{"name":"Current Urology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44309131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transurethral guidewire loop for manipulation and extraction of stent: A novel, innovative, video-endoscopic technique in ureteral stent removal","authors":"Ahmed Adam, M. Perera","doi":"10.1097/cu9.0000000000000170","DOIUrl":"https://doi.org/10.1097/cu9.0000000000000170","url":null,"abstract":"","PeriodicalId":39147,"journal":{"name":"Current Urology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49516055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laparoscopic robotic takedown ureterostomy with extravesical cross-trigonal reimplantation after end cutaneous ureterostomy","authors":"Binyamin B. Neeman, S. Kocherov, J. Jaber, A. Neheman, B. Chertin","doi":"10.1097/cu9.0000000000000174","DOIUrl":"https://doi.org/10.1097/cu9.0000000000000174","url":null,"abstract":"","PeriodicalId":39147,"journal":{"name":"Current Urology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44315356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histopathologic features and parameters predicting recurrence potential of small renal masses","authors":"S. Bajramović, Berina Hasanović, J. Alić, N. Šabanović Bajramović, Damir Aganović","doi":"10.1097/cu9.0000000000000175","DOIUrl":"https://doi.org/10.1097/cu9.0000000000000175","url":null,"abstract":"","PeriodicalId":39147,"journal":{"name":"Current Urology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46357255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing health literacy and subsequent implementation of an animated video to enhance understanding for patients with nephrolithiasis","authors":"Anand Prabhu, J. Bylund, J. Bell, A. Bhalodi, Andrew M. Harris","doi":"10.1097/cu9.0000000000000172","DOIUrl":"https://doi.org/10.1097/cu9.0000000000000172","url":null,"abstract":"","PeriodicalId":39147,"journal":{"name":"Current Urology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42464180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prostate cancer screening: Continued controversies and novel biomarker advancements.","authors":"Atiyah Tidd-Johnson,&nbsp;Sneha Annie Sebastian,&nbsp;Edzel Lorraine Co,&nbsp;Munaza Afaq,&nbsp;Hansini Kochhar,&nbsp;Mona Sheikh,&nbsp;Arpit Mago,&nbsp;Sujan Poudel,&nbsp;John A Fernandez,&nbsp;Ivan D Rodriguez,&nbsp;Sanjay Razdan","doi":"10.1097/CU9.0000000000000145","DOIUrl":"https://doi.org/10.1097/CU9.0000000000000145","url":null,"abstract":"<p><p>Prostate cancer (PCa) screening remains one of the most controversial topics in clinical and public health. Despite being the second most common cancer in men worldwide, recommendations for screening using prostate-specific antigen (PSA) are unclear. Early detection and the resulting postscreening treatment lead to overdiagnosis and overtreatment of otherwise indolent cases. In addition, several unwanted harms are associated with PCa screening process. This literature review focuses on the limitations of PSA-specific PCa screening, reasons behind the screening controversy, and the novel biomarkers and advanced innovative methodologies that improve the limitations of traditional screening using PSA. With the verdict of whether or not to screen not yet unanimous, we hope to aid in resolution of the long-standing debate.</p>","PeriodicalId":39147,"journal":{"name":"Current Urology","volume":"16 4","pages":"197-206"},"PeriodicalIF":1.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/22/cc/curr-urol-16-197.PMC9875204.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9137318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}