Schizophrenia Research-Cognition最新文献

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Modulation of hemispheric asymmetry in executive control of attention in schizophrenia with atypical antipsychotic treatment: Potential benefits of olanzapine 非典型抗精神病药物治疗对精神分裂症患者注意执行控制半球不对称的调节:奥氮平的潜在益处
IF 2.8
Schizophrenia Research-Cognition Pub Date : 2024-03-06 DOI: 10.1016/j.scog.2024.100306
Yong Zhao , Yifan Li , Jing Du , Chuanlong Fang , Wansheng Li , Mengyu Lv , Yue Wu , Kai Wang , Tingting Wu , Yanghua Tian , Juanjuan Zhang
{"title":"Modulation of hemispheric asymmetry in executive control of attention in schizophrenia with atypical antipsychotic treatment: Potential benefits of olanzapine","authors":"Yong Zhao ,&nbsp;Yifan Li ,&nbsp;Jing Du ,&nbsp;Chuanlong Fang ,&nbsp;Wansheng Li ,&nbsp;Mengyu Lv ,&nbsp;Yue Wu ,&nbsp;Kai Wang ,&nbsp;Tingting Wu ,&nbsp;Yanghua Tian ,&nbsp;Juanjuan Zhang","doi":"10.1016/j.scog.2024.100306","DOIUrl":"https://doi.org/10.1016/j.scog.2024.100306","url":null,"abstract":"<div><p>Deficits in executive control of attention have been reported in schizophrenia patients, but can be ameliorated by treatment of atypical antipsychotics along with the symptoms. However, it remains unclear whether this effect is related to a modulation of hemispheric asymmetry in executive control by the medicine. In this behavioral study, we employed a lateralized version of the attention network test to examine the hemispheric asymmetry of executive control in schizophrenia patients before and after olanzapine treatment, compared to matched healthy controls. Executive control was measured as a conflict effect, indexed as the response time (RT) difference between incongruent versus congruent flanker conditions, and was compared between stimuli presented in the left and the right visual field (i.e., processed by right versus left hemisphere of the brain). Results showed that pre-treatment schizophrenia patients revealed a right hemisphere superiority in conflict effect (i.e., a smaller effect in the right hemisphere than in the left hemisphere), driven by the incongruent condition. Olanzapine treatment reduced this right hemisphere superiority by improving the efficiency of the left hemisphere in the incongruent condition. These results suggested that olanzapine treatment may improve the efficiency of executive control in the left hemisphere in schizophrenia patients.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"36 ","pages":"Article 100306"},"PeriodicalIF":2.8,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215001324000076/pdfft?md5=6d1288b55e8a6db482e758adf9cbb0ed&pid=1-s2.0-S2215001324000076-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140041709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between the HHEX polymorphism and delayed memory in first-episode schizophrenic patients HHEX 多态性与首发精神分裂症患者延迟记忆之间的关系
IF 2.8
Schizophrenia Research-Cognition Pub Date : 2024-02-29 DOI: 10.1016/j.scog.2024.100304
Zhen Hua Zhu , Xu Yuan Yin , Yuan Cai , Ning Ning Jia, Pei Jie Wang, Qi Qi, Wen Long Hou, Li Juan Man, Li Hui
{"title":"Association between the HHEX polymorphism and delayed memory in first-episode schizophrenic patients","authors":"Zhen Hua Zhu ,&nbsp;Xu Yuan Yin ,&nbsp;Yuan Cai ,&nbsp;Ning Ning Jia,&nbsp;Pei Jie Wang,&nbsp;Qi Qi,&nbsp;Wen Long Hou,&nbsp;Li Juan Man,&nbsp;Li Hui","doi":"10.1016/j.scog.2024.100304","DOIUrl":"https://doi.org/10.1016/j.scog.2024.100304","url":null,"abstract":"<div><p>The hematopoietically-expressed homeobox gene (<em>HHEX</em>) played a critical role in regulating the immune system that the abnormality of which was involved in the psychopathology and cognitive deficits of psychiatric disorders. The aim of this study was to investigate the effect of <em>HHEX</em> rs1111875 polymorphism on the susceptibility and cognitive deficits of first-episode schizophrenic patients (FSP). We assessed cognitive function in 239 first-episode patients meeting DSM-IV for schizophrenia, and 368 healthy controls using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). The <em>HHEX</em> rs1111875 polymorphism was genotyped. Our results showed that the allelic and genotypic frequencies of <em>HHEX</em> rs1111875 polymorphism didn't differ between FSP and healthy controls (both <em>p</em> &gt; 0.05) after adjusting for sex and age. Cognitive test scores in FSP were significantly lower than those in healthy controls on all scales (all <em>p</em> &lt; 0.001) except for the visuospatial/constructional score (<em>p</em> &gt; 0.05) after adjusting for covariates. There was a significant genotype (<em>p</em> &lt; 0.05) rather than genotype × diagnosis (<em>p</em> &gt; 0.05) effect on the delayed memory score after adjusting for covariates. The <em>HHEX</em> rs1111875 polymorphism was significantly associated with the delayed memory score in FSP (<em>p</em> &lt; 0.05), but not in healthy controls (<em>p</em> &gt; 0.05) after adjusting for covariates. Our findings supported that the <em>HHEX</em> rs1111875 polymorphism did not contribute to the susceptibility to FSP. However, this polymorphism might influence the delayed memory in FSP. Moreover, FSP had poorer cognitive function than healthy controls except for the visuospatial/constructional domain.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"36 ","pages":"Article 100304"},"PeriodicalIF":2.8,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215001324000052/pdfft?md5=b564fe8ebdeb78249546fe3e59641d9e&pid=1-s2.0-S2215001324000052-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139992564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the editor: “Associative learning and facial expression recognition in schizophrenic patients: Effects of social presence” and “Does cannabis affect cognitive functioning in patients with schizophrenia?” 致编辑的信:"精神分裂症患者的联想学习和面部表情识别:社会存在的影响 "和 "大麻会影响精神分裂症患者的认知功能吗?
IF 2.8
Schizophrenia Research-Cognition Pub Date : 2024-02-21 DOI: 10.1016/j.scog.2024.100303
Mehmet Hamdi Örüm
{"title":"Letter to the editor: “Associative learning and facial expression recognition in schizophrenic patients: Effects of social presence” and “Does cannabis affect cognitive functioning in patients with schizophrenia?”","authors":"Mehmet Hamdi Örüm","doi":"10.1016/j.scog.2024.100303","DOIUrl":"https://doi.org/10.1016/j.scog.2024.100303","url":null,"abstract":"","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"36 ","pages":"Article 100303"},"PeriodicalIF":2.8,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215001324000040/pdfft?md5=8c508213df5f70de6ad5ce7d7b1e21bd&pid=1-s2.0-S2215001324000040-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139936343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Face and emotion recognition in individuals diagnosed with schizophrenia, ultra-high risk for psychosis, unaffected siblings, and healthy controls in a sample from Turkey 土耳其样本中被诊断为精神分裂症患者、超高精神病风险患者、未受影响的兄弟姐妹和健康对照组的人脸和情绪识别能力
IF 2.8
Schizophrenia Research-Cognition Pub Date : 2024-02-03 DOI: 10.1016/j.scog.2024.100301
Meylin Sağdıç , Busra Izgi , Hale Yapici Eser , Mete Ercis , Alp Üçok , Kemal Kuşçu
{"title":"Face and emotion recognition in individuals diagnosed with schizophrenia, ultra-high risk for psychosis, unaffected siblings, and healthy controls in a sample from Turkey","authors":"Meylin Sağdıç ,&nbsp;Busra Izgi ,&nbsp;Hale Yapici Eser ,&nbsp;Mete Ercis ,&nbsp;Alp Üçok ,&nbsp;Kemal Kuşçu","doi":"10.1016/j.scog.2024.100301","DOIUrl":"https://doi.org/10.1016/j.scog.2024.100301","url":null,"abstract":"<div><p>Face and emotion recognition are crucial components of social cognition. We aimed to compare them in patients diagnosed with schizophrenia (SCZ), ultra-high risk for psychosis (UHR), unaffected siblings of schizophrenia patients (SIB), and healthy controls (HC). Methods: One hundred sixty-six participants (45 SCZ, 14 UHR, 45 SIB, and 62 HC) were interviewed with the Structured Clinical Interview for DSM-5 (SCID-5). Positive and Negative syndrome scale (PANSS), PennCNB Facial Memory (CPF), and Emotion Recognition Task (ER40) were applied. Results: In CPF, SCZ performed significantly lower than SIB and HC. SIB was also significantly lower than HC for total correct responses. The sample size of the UHR group was small, and the statistical comparisons did not reach a significance, however, a trend towards decreased performance between the SCZ and SIB was found. In ER40, SCZ performed significantly lower than HC and SIB in all domains, except for the insignificant findings for angry ER between SIB and SCZ. SIB also performed significantly lower than HC for angry, negative, and total ER. UHR was similar to SCZ for happy and sad ER and performed significantly lower than HC for happy ER. The effect of SCZ diagnosis on the efficiency of CPF and ER40 was significant when corrected for age and education. For SCZ, PANSS also significantly affected the CPF and ER40. Conclusion: Our findings suggest varying levels of face and emotion recognition deficits in individuals with SCZ, UHR, and SIB. Face and emotion recognition deficits are promising schizophrenia endophenotypes related to social cognition.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"36 ","pages":"Article 100301"},"PeriodicalIF":2.8,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215001324000027/pdfft?md5=d37998e11d62fbeeed315aef9dd08ef0&pid=1-s2.0-S2215001324000027-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139674576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive impairment in early stages of psychosis 将蒙特利尔认知评估(MoCA)作为精神病早期认知障碍的筛查工具
IF 2.8
Schizophrenia Research-Cognition Pub Date : 2024-01-29 DOI: 10.1016/j.scog.2024.100302
Sebastian Corral , Pablo A. Gaspar , Rolando I. Castillo-Passi , Rocío Mayol Troncoso , Adrian P. Mundt , Yuriy Ignatyev , Rodrigo R. Nieto , Alicia Figueroa-Muñoz
{"title":"Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive impairment in early stages of psychosis","authors":"Sebastian Corral ,&nbsp;Pablo A. Gaspar ,&nbsp;Rolando I. Castillo-Passi ,&nbsp;Rocío Mayol Troncoso ,&nbsp;Adrian P. Mundt ,&nbsp;Yuriy Ignatyev ,&nbsp;Rodrigo R. Nieto ,&nbsp;Alicia Figueroa-Muñoz","doi":"10.1016/j.scog.2024.100302","DOIUrl":"https://doi.org/10.1016/j.scog.2024.100302","url":null,"abstract":"<div><h3>Background</h3><p>Cognitive alterations have been reported in early stages of psychosis including people with First Episode Psychosis (FEP), Clinical High-Risk Mental State (CHR), and Psychotic-Like Experience (PLE). This study aimed to compare the cognitive function in early stages of psychosis using the Montreal Cognitive Assessment (MoCA), a low-cost and brief assessment tool of cognitive functions.</p></div><div><h3>Methods</h3><p>A total of 154 individuals, including 35 with FEP, 38 CHR, 44 PLE, and 37 healthy controls (HC), were evaluated with the MoCA in Santiago, Chile. We calculated the mean total score of the MoCA and the standard deviation of the mean. Groups were assessed for a trend to lower scores in a pre-determined sequence (HC &gt; PLE &gt; CHR &gt; FEP) using the Jonckheere-Terpstra test (T<sub>JT</sub>).</p></div><div><h3>Results</h3><p>The mean total MoCA scores were 24.8 ± 3.3 in FEP, 26.4 ± 2.4 in CHR, 26.4 ± 2.3 in PLE, and 27.2 ± 1.8 in HC. The analyses revealed a significant trend (<em>p</em> &lt; 0.05) toward lower MoCA individual domain scores and MoCA total scores in the following order: HC &gt; PLE &gt; CHR &gt; FEP. The mean total scores of all groups were above the cut-off for cognitive impairment (22 points).</p></div><div><h3>Conclusions</h3><p>The MoCA describes lower scores in cognition across early stages of psychosis and may be a useful low-cost assessment instrument in early intervention centers of poorly resourced settings.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"36 ","pages":"Article 100302"},"PeriodicalIF":2.8,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215001324000039/pdfft?md5=587b5439eb1eff38cb600473207ca4c7&pid=1-s2.0-S2215001324000039-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139653021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between anemia and its correlates and cognitive function in Chinese patients with chronic schizophrenia: A large cross-sectional study 中国慢性精神分裂症患者贫血及其相关因素与认知功能之间的关系:大型横断面研究
IF 2.8
Schizophrenia Research-Cognition Pub Date : 2024-01-15 DOI: 10.1016/j.scog.2024.100300
Yang Jiang , Yi Cai , Yaoyao Lu , Guanghui Wu , Xiang-Yang Zhang
{"title":"Relationship between anemia and its correlates and cognitive function in Chinese patients with chronic schizophrenia: A large cross-sectional study","authors":"Yang Jiang ,&nbsp;Yi Cai ,&nbsp;Yaoyao Lu ,&nbsp;Guanghui Wu ,&nbsp;Xiang-Yang Zhang","doi":"10.1016/j.scog.2024.100300","DOIUrl":"https://doi.org/10.1016/j.scog.2024.100300","url":null,"abstract":"<div><h3>Background</h3><p>Although both anemia and schizophrenia (SCZ) can cause cognitive decline, it is unclear whether anemia worsens cognitive decline in patients with SCZ. The primary objective of this study was to investigate the prevalence of anemia and the relationship between anemia, SCZ symptom severity, and cognitive function in patients with SCZ.</p></div><div><h3>Methods</h3><p>We obtained demographic and clinical data from 1690 inpatients with SCZ. All psychiatric symptoms and cognitive functioning were assessed by the Positive and Negative Syndrome Scale (PANSS), the Mini-Mental State Examination (MMSE), and the Repeated Battery for the Assessment of Neuropsychological Status (RBANS). Hemoglobin (HGB) values as well as red blood cell (RBC) counts were collected by routine blood tests.</p></div><div><h3>Results</h3><p>The proportion of anemia in patients with SCZ was 26.36 % (383/1453). Compared to SCZ patients without anemia, SCZ patients with anemia were older, had a lower bodyweight, a smaller waist circumference and lower apolipoprotein B levels, but longer QT intervals. Further logistic regression analysis revealed that anemia was associated with age, gender, and weight. In addition, there was no difference in cognitive function between SCZ patients with and without anemia.</p></div><div><h3>Conclusion</h3><p>Our findings suggest a high proportion of anemia in patients with chronic SCZ in the Han Chinese population. Several demographic and clinical variables are associated with anemia in SCZ patients.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"36 ","pages":"Article 100300"},"PeriodicalIF":2.8,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215001324000015/pdfft?md5=6d3386b437b972b7a0075de28ca6d8d5&pid=1-s2.0-S2215001324000015-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139467969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does cannabis affect cognitive functioning in patients with schizophrenia? 大麻会影响精神分裂症患者的认知功能吗?
IF 2.8
Schizophrenia Research-Cognition Pub Date : 2023-12-20 DOI: 10.1016/j.scog.2023.100299
Hajar Rachid , Zineb Saif , Salma Raoui , Zineb Serhier , Mohamed Agoub
{"title":"Does cannabis affect cognitive functioning in patients with schizophrenia?","authors":"Hajar Rachid ,&nbsp;Zineb Saif ,&nbsp;Salma Raoui ,&nbsp;Zineb Serhier ,&nbsp;Mohamed Agoub","doi":"10.1016/j.scog.2023.100299","DOIUrl":"https://doi.org/10.1016/j.scog.2023.100299","url":null,"abstract":"<div><h3>Introduction</h3><p>Cannabis use impairs cognitive performance in healthy subjects; several studies have shown improved cognitive outcomes in schizophrenic patients using cannabis. The aim of this study was to evaluate the effects of cannabis use on cognitive function in Moroccan patients with schizophrenia who were cannabis users.</p></div><div><h3>Method</h3><p>Two groups were recruited in a Moroccan University Psychiatric Centre. Fifty patients diagnosed with schizophrenia according to the DSM-V who were cannabis users (SZ CANN +) and forty-nine patients diagnosed with schizophrenia according to DSM-V who do not use cannabis (SZ CANN-). Cognitive functioning was assessed using the CogState neuropsychological battery.</p></div><div><h3>Results</h3><p>The results of the study suggest that SZ CANN- patients performed better in the test of psychomotor function, attention and verbal memory. While SZ CANN+ patients performed better in the test of working memory, visual memory and emotional recognition. We found no relationship between SZ CANN+ patients and SZ CANN- patients concerning executive function.</p></div><div><h3>Conclusions</h3><p>Our results suggest that cannabis use may have different effects on neurocognitive functioning. It is associated with disorders of psychomotor function, attention and verbal memory. So, it is associated with an improvement in working memory, visual memory and emotion recognition.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"36 ","pages":"Article 100299"},"PeriodicalIF":2.8,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215001323000227/pdfft?md5=a01c48f832d65f3124deb88aab6d911f&pid=1-s2.0-S2215001323000227-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139033679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between negative and positive automatic thoughts and clinical variables in patients with schizophrenia 精神分裂症患者消极和积极自动思维与临床变量之间的关系
IF 2.8
Schizophrenia Research-Cognition Pub Date : 2023-12-02 DOI: 10.1016/j.scog.2023.100298
Tomoya Takeda, Masahito Nakataki, Hidehiro Umehara, Shusuke Numata
{"title":"Associations between negative and positive automatic thoughts and clinical variables in patients with schizophrenia","authors":"Tomoya Takeda,&nbsp;Masahito Nakataki,&nbsp;Hidehiro Umehara,&nbsp;Shusuke Numata","doi":"10.1016/j.scog.2023.100298","DOIUrl":"https://doi.org/10.1016/j.scog.2023.100298","url":null,"abstract":"<div><p>This study investigated the relationships between negative and positive automatic thoughts and clinical variables in patients with schizophrenia. The participants included 36 patients with schizophrenia (male = 16; female = 20; age = 42.86 ± 9.40) who were outpatients in the Department of Psychiatry at Tokushima University Hospital. We used the Automatic Thoughts Questionnaire-Revised (ATQ-R), Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schizophrenia (CDSS), and Brief Assessment of Cognition in Schizophrenia (BACS) to assess negative and positive automatic thoughts, positive and negative symptoms, depressive symptoms, and neurocognition, respectively. Spearman rank correlation coefficients were calculated to determine the relationships between negative and positive automatic thoughts and clinical variables. No relationship was observed between negative and positive automatic thoughts. Negative automatic thoughts were related to depressive symptoms. Positive automatic thoughts were related to neurocognition. We therefore surmise that each automatic thought might have different clinical features and outcomes, and should therefore be treated accordingly.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"35 ","pages":"Article 100298"},"PeriodicalIF":2.8,"publicationDate":"2023-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215001323000215/pdfft?md5=7c9fe04c7bce11908edd26e9ecfd7e26&pid=1-s2.0-S2215001323000215-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138475108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Range adaptation in schizophrenia: A one-year longitudinal study 精神分裂症的范围适应:一项为期一年的纵向研究
IF 2.8
Schizophrenia Research-Cognition Pub Date : 2023-11-30 DOI: 10.1016/j.scog.2023.100297
Ling-ling Wang , Jing-bo Gong , Yi-hang Huang , Shu-hong Shi , Chao Yan , Hui-xin Hu , Yi Wang , Simon S.Y. Lui , Kang Ju , Raymond C.K. Chan
{"title":"Range adaptation in schizophrenia: A one-year longitudinal study","authors":"Ling-ling Wang ,&nbsp;Jing-bo Gong ,&nbsp;Yi-hang Huang ,&nbsp;Shu-hong Shi ,&nbsp;Chao Yan ,&nbsp;Hui-xin Hu ,&nbsp;Yi Wang ,&nbsp;Simon S.Y. Lui ,&nbsp;Kang Ju ,&nbsp;Raymond C.K. Chan","doi":"10.1016/j.scog.2023.100297","DOIUrl":"https://doi.org/10.1016/j.scog.2023.100297","url":null,"abstract":"<div><p>Range adaptation refers to the representation of a stimulus value based on its relative position in the range of pre-experienced values. Altered range adaptation in value representation may be related to motivation and pleasure (MAP) deficit in schizophrenia (SCZ). This follow-up study examined the relationship between range adaptation performance and MAP symptoms in SCZ patients. We recruited 26 schizophrenia patients and followed them for 1 year. They completed an experimental task for estimating their range adaptation to outcome value (OV) and expected value (EV) at baseline and after 1 year. At baseline, we found a marginally significant and negative correlation between OV adaptation and avolition symptoms in SCZ patients. Moreover, the 1-year change of EV adaptation was significantly and negatively correlated with the change of self-report pleasure experience. Our results suggest that range adaptation may track the variations of MAP symptoms in SCZ.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"35 ","pages":"Article 100297"},"PeriodicalIF":2.8,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215001323000203/pdfft?md5=c0042dc8ed6ff96c447c81b063bb116f&pid=1-s2.0-S2215001323000203-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138467702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Category Fluency Test components and their association with cognition and symptoms in adolescents with schizophrenia 青少年精神分裂症的类别流畅性测试成分及其与认知和症状的关系
IF 2.8
Schizophrenia Research-Cognition Pub Date : 2023-11-10 DOI: 10.1016/j.scog.2023.100296
Rogelio Apiquian , Ricardo Díaz , Gamaliel Victoria , Rosa-Elena Ulloa
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