The implementation and effectiveness of Integrated Psychological Therapy (IPT) in chronic middle-aged inpatients with schizophrenia

IF 2.3 Q2 PSYCHIATRY
Aikaterini Poulou , Fotios Anagnostopoulos , Argiro Vatakis , Robert C. Mellon , Daniel R. Mueller
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Abstract

Introduction

Cognitive rehabilitation is essential for schizophrenia treatment since it improves function. Moreover, the relationship between cognitive rehabilitation and functioning is significantly affected by negative symptoms and social cognition. Integrated Psychological Therapy (IPT) is a promising approach that integrates interventions in neurocognition, social cognition, and functional level. This study examines IPT's efficacy in chronic middle-aged inpatients.

Methods

A randomized controlled study involved 44 individuals with schizophrenia. Twenty-one IPT participants received 50 biweekly sessions and medication, while twenty-three control participants received treatment as usual/supportive therapy and pharmacotherapy. Pre- and post-intervention and six- and twelve-month follow-ups were arranged to assess neurocognition, social perception, psychopathology, and functioning using the Matrics Consensus Cognitive Battery, Social Perception Scale, Positive and Negative Syndrome Scale, and Global Assessment of Functioning.

Results

Speed of processing, attention/vigilance, overall composite, and neurocognitive composite scores improved significantly in the IPT group. Social Perception Scale performance improved in all areas after the intervention and persisted for 6 months. Positive, negative, and total psychopathology symptoms decreased significantly post-intervention and at the 12-month follow-up, whereas participants' functioning improved significantly.

Conclusions

Middle-aged chronic inpatients with schizophrenia may benefit from IPT in neurocognition, social perception, psychopathology, and functioning. This field of study may provide insight into schizophrenia treatment, hence further research is encouraged.
综合心理疗法(IPT)在慢性中年精神分裂症住院患者中的实施情况和效果
导言:认知康复对精神分裂症的治疗至关重要,因为它能改善患者的功能。此外,认知康复与功能之间的关系受到阴性症状和社会认知的显著影响。综合心理疗法(IPT)是一种将神经认知、社会认知和功能水平的干预结合在一起的有前途的方法。本研究探讨了综合心理疗法对慢性中年住院患者的疗效。21 名 IPT 参与者接受了 50 次双周疗程和药物治疗,23 名对照组参与者接受了常规治疗/支持疗法和药物治疗。干预前、干预后以及6个月和12个月的随访安排使用Matrics共识认知电池、社会感知量表、正负综合征量表和功能全面评估来评估神经认知、社会感知、精神病理学和功能。干预后,社会认知量表在所有方面的表现都有所改善,并持续了 6 个月。干预后和随访 12 个月时,阳性、阴性和总的精神病理症状明显减少,而参与者的功能则明显改善。这一研究领域可为精神分裂症的治疗提供启示,因此鼓励进一步开展研究。
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来源期刊
CiteScore
5.60
自引率
10.70%
发文量
54
审稿时长
67 days
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