Schizophrenia Research-Cognition最新文献

{"title":"Cognitive and perceptual impairments in schizophrenia extend to other psychotic disorders but not schizotypy","authors":"Natalie Frattaroli ,&nbsp;Mia Geljic ,&nbsp;Dominika Runkowska ,&nbsp;Hayley Darke ,&nbsp;Caitlin Reddyhough ,&nbsp;Taylor Mills ,&nbsp;Matthew Mitchell ,&nbsp;Rachel Hill ,&nbsp;Olivia Carter ,&nbsp;Suresh Sundram","doi":"10.1016/j.scog.2022.100266","DOIUrl":"10.1016/j.scog.2022.100266","url":null,"abstract":"<div><p>Well characterised cognitive and perceptual impairments in schizophrenia may not be diagnostically specific with some studies suggesting no significant differences between psychotic disorders. This transdiagnostic ambiguity is paralleled in the boundary distinctions between psychotic disorders and the sub-threshold symptomatology of schizotypy. The current study used the CNTRACS test battery to explore if performance deficits in visual integration, relational memory and goal maintenance were specific to schizophrenia or extend to other psychotic disorders; and if task performance varied between individuals with schizophrenia and schizotypy in healthy adults. The sample consisted of healthy controls, and patients who met DSM-IV criteria for schizophrenia, other psychotic disorders and non-psychotic disorders who were tested in person; and an online sample of self-assessed healthy adults. No significant differences were found in performance between patients with schizophrenia and other psychotic disorders in contrast to non-psychotic disorders and healthy controls. The high schizotypy group performed better on the tasks compared to the other psychoses and schizophrenia groups. There were no differences in the healthy control group between individuals with high versus low schizotypy or between in-person and online task performance. These findings support the notion that cognitive and perceptual impairments in schizophrenia extend to other psychotic disorders but are discontinuous with schizotypy. This study provides insights into similarities between schizophrenia and other psychotic disorders with regards to the potential neural substrates underpinning these functions and supports the use of online tools for assessing domains of cognition and perception.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"30 ","pages":"Article 100266"},"PeriodicalIF":2.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/e3/main.PMC9361330.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40692531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subjective cognitive complaints in first episode psychosis: A focused follow-up on sex effect and alcohol usage","authors":"E. Stip ,&nbsp;F. Al Mugaddam ,&nbsp;J. Nauman ,&nbsp;A. Abdel Baki ,&nbsp;S. Potvin","doi":"10.1016/j.scog.2022.100267","DOIUrl":"10.1016/j.scog.2022.100267","url":null,"abstract":"<div><p>A network of early psychosis-specific intervention programs at the University of Montreal in Montreal, Quebec, Canada, conducted a longitudinal naturalistic five-year study at two Urban Early Intervention Services (EIS). In this study, 198 patients were recruited based on inclusion/exclusion criteria and agreed to participate. Our objectives were to assess the subjective cognition complaints of schizophrenic patients assessed by Subjective Scale to Investigate Cognition in Schizophrenia (SSTICS) in their first-episode psychosis (FEP) in relation to their general characteristics. We also wanted to assess whether there are sex-based differences in the subjective cognitive complaints, as well as differences in cognitive complaints among patients who use alcohol in comparison to those who are abstainers. Additionally, we wanted to monitor the changes in the subjective complaints progress for a period of five years follow-up. Our findings showed that although women expressed more cognitive complaints than men [mean (SD) SSTICS, 28.2 (13.7) for women and 24.7 (13.2) for men], this difference was not statistically significant (<em>r</em> = −0.190, 95 % CI, −0. 435 to 0. 097). We also found that abstainers complained more about their cognition than alcohol consumers [mean (SD) SSTICS, 27.9 (13.4) for abstainers and 23.7 (12.9) for consumers], a difference which was statistically significant (<em>r</em> = −0.166, 95 % CI, −0. 307 to −0.014). Our findings showed a drop in the average score of SSTICS through study follow-up time among FEP patients. In conclusion, we suggest that if we want to set up a good cognitive remediation program, it is useful to start with the patients' demands. This demand can follow the patients' complaints. Further investigations are needed in order to propose different approaches between alcohol users and abstinent patients concerning responding to their cognitive complaints.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"30 ","pages":"Article 100267"},"PeriodicalIF":2.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/70/f9/main.PMC9420513.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40332496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dispersion of cognitive performance test scores on the MATRICS Consensus Cognitive Battery: A different perspective","authors":"David J. Williamson ,&nbsp;Keith H. Nuechterlein ,&nbsp;Todd Tishler ,&nbsp;Joseph Ventura ,&nbsp;Benjamin M. Ellingson ,&nbsp;Ibrahim Turkoz ,&nbsp;Richard S.E. Keefe ,&nbsp;Larry Alphs","doi":"10.1016/j.scog.2022.100270","DOIUrl":"10.1016/j.scog.2022.100270","url":null,"abstract":"<div><h3>Objective</h3><p>Persons with schizophrenia exhibit greater neurocognitive test score dispersion. Here, we seek to characterize dispersion on the Neurocognitive Composite subtests of the Measurement of Treatment Research to Improve Cognition in Schizophrena Consensus Cognitive Battery (MCCB) and determine the relative effects of different antipsychotic formulations on dispersion and mean performance.</p></div><div><h3>Method</h3><p>In this post hoc analysis of the DREaM study (<span>NCT02431702</span><svg><path></path></svg>), which compared treatment with paliperidone palmitate (PP) long-acting injectable with oral antipsychotic (OAP) treatment over 18 months, dispersion in MCCB neurocognitive subtest performance was calculated for each participant by visit (test occasion).</p></div><div><h3>Results</h3><p>Over 18 months, mean neurocognitive performance improved in a manner consistent with the expected effects of practice in both groups (<em>p</em> &lt; 0.05); this improvement was observed during the first 9 months (PP: <em>p</em> &lt; 0.05, OAP: <em>p</em> &lt; 0.001), followed by stable performance over the second 9 months (PP: <em>p</em> = 0.821, OAP: <em>p</em> = 0.375). Rates of change did not differ between groups (treatment-by-visit interaction: <em>p</em> = 0.548). In contrast, analyses of dispersion focusing on contrasts between baselines and end points of the first and second 9 months revealed different patterns. Over the first 9 months, dispersion in both groups lessened to a similar extent. However, over the second 9 months, dispersion remained stable in the PP group, whereas neurocognitive performance became significantly more variable in the OAP group (<em>p</em> &lt; 0.01).</p></div><div><h3>Conclusion</h3><p>Dispersion of neurocognitive test scores provides a different index of cognitive change than that provided by composite scores. Long-term maintenance of therapeutic levels provided by PP over time may limit (relative to oral AP) the extent to which cognitive performance becomes more variable.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"30 ","pages":"Article 100270"},"PeriodicalIF":2.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/10/08/main.PMC9468588.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40362363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preface to Virtual Special Issue: Cognitive impairments in an increasingly digital world","authors":"Philip D. Harvey ,&nbsp;Anne-Kathrin J. Fett ,&nbsp;Eva Velthorst","doi":"10.1016/j.scog.2022.100262","DOIUrl":"10.1016/j.scog.2022.100262","url":null,"abstract":"","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"30 ","pages":"Article 100262"},"PeriodicalIF":2.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c7/6c/main.PMC9477850.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40367111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Domain-specific cognitive course in schizophrenia: Group- and individual-level changes over 10 years","authors":"Camilla Bärthel Flaaten ,&nbsp;Ingrid Melle ,&nbsp;Thomas Bjella ,&nbsp;Magnus Johan Engen ,&nbsp;Gina Åsbø ,&nbsp;Kristin Fjelnseth Wold ,&nbsp;Line Widing ,&nbsp;Erlend Gardsjord ,&nbsp;Linn-Sofie Sæther ,&nbsp;Merete Glenne Øie ,&nbsp;Siv Hege Lyngstad ,&nbsp;Beathe Haatveit ,&nbsp;Carmen Simonsen ,&nbsp;Torill Ueland","doi":"10.1016/j.scog.2022.100263","DOIUrl":"10.1016/j.scog.2022.100263","url":null,"abstract":"<div><p>Cognitive impairments in schizophrenia are well-documented, present across several cognitive domains and found to be relatively stable over time. However, there is a high degree of heterogeneity and indications of domain-specific developmental courses. The present study investigated the 10-year cognitive course in participants with first-episode schizophrenia (FES) and healthy controls on eight cognitive domains and a composite score, looking at group- and individual-level changes.</p><p>A total of 75 FES participants and 91 healthy controls underwent cognitive assessment at baseline and follow-up. Linear mixed models were used for group-level analyses and reliable change index (RCI) analyses were used to investigate individual change. The prevalence of clinically significant impairment was explored at both time points, using a cut-off of &lt; −1.5 SD, with significant cognitive impairment defined as impairment on ≥2 domains.</p><p>Group-level analyses found main effects of group and time, and time by group interactions. Memory, psychomotor processing speed and verbal fluency improved, while learning, mental processing speed and working memory were stable in both groups. FES participants showed deteriorations in attention and cognitive control. Individual-level analyses mainly indicated stability in both FES and controls, except for a higher prevalence of decline in cognitive control in FES. At baseline, 68.8 % of FES participants had clinically significant impairment, compared to 62.3 % at follow-up.</p><p>We mainly found long-term stability and modest increases in cognition over time in FES, as well as a high degree of within-group heterogeneity. We also found indications of deterioration in participants with worse cognitive performance at baseline.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"30 ","pages":"Article 100263"},"PeriodicalIF":2.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40476537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional neurodevelopment of working memory in early-onset schizophrenia: A longitudinal FMRI study","authors":"Vasileios Ioakeimidis ,&nbsp;Corinna Haenschel ,&nbsp;Anne-Kathrin Fett ,&nbsp;Marinos Kyriakopoulos ,&nbsp;Danai Dima","doi":"10.1016/j.scog.2022.100268","DOIUrl":"10.1016/j.scog.2022.100268","url":null,"abstract":"<div><p>Schizophrenia, a debilitating disorder with typical manifestation of clinical symptoms in early adulthood, is characterized by cognitive impairments in executive processes such as in working memory (WM). However, there is a rare case of individuals with early-onset schizophrenia (EOS) starting before their 18th birthday, while WM and its neural substrates are still undergoing maturation. Using the WM n-back task with functional magnetic resonance imaging, we assessed the functional neurodevelopment of WM in adolescents with EOS and age- and gender-matched typically developing controls. Participants underwent neuroimaging in the same scanner twice, once at age 17 and at 21 (mean interscan interval = 4.3 years). General linear model analysis was performed to explore WM neurodevelopmental changes within and between groups. Psychopathological scores were entered in multiple regressions to detect brain regions whose longitudinal functional change was predicted by baseline symptoms in EOS. WM neurodevelopment was characterized by widespread functional reductions in frontotemporal and cingulate brain areas in patients and controls. No between-group differences were found in the trajectory of WM change. Baseline symptom scores predicted functional neurodevelopmental changes in frontal, cingulate, parietal, occipital, and cerebellar areas. The adolescent brain undergoes developmental processes such as synaptic pruning, which may underlie the refinement WM of network. Prefrontal and parietooccipital activity reduction is affected by clinical presentation of symptoms. Using longitudinal neuroimaging methods in a rare diagnostic sample of patients with EOS may help the advancement of neurodevelopmental biomarkers intended as pharmacological targets to tackle WM impairment.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"30 ","pages":"Article 100268"},"PeriodicalIF":2.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2e/59/main.PMC9372770.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40612446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social cognitive heterogeneity in schizophrenia: A cluster analysis","authors":"Anja Vaskinn ,&nbsp;Kjetil Sundet ,&nbsp;Beathe Haatveit","doi":"10.1016/j.scog.2022.100264","DOIUrl":"10.1016/j.scog.2022.100264","url":null,"abstract":"<div><p>This study examined social cognitive heterogeneity in Norwegian sample of individuals with schizophrenia (n = 82). They were assessed with three social cognitive tests: Emotion in Biological Motion (emotion processing), Relationships Across Domains (social perception), and Movie for the Assessment of Social Cognition (theory of mind). Hierarchical and <em>k</em>-means cluster analyses using standardized scores on these three tests provided two clusters. The first cluster (68 %) had mild social cognitive impairments (&lt;0.5 standard deviations below healthy comparison participants). The second cluster (32 %) had severe social cognitive impairments (&gt;2 standard deviations below healthy comparison participants). Validity of the two social cognitive subgroups was indicated by significant differences in functioning, symptom load and nonsocial cognition. Our study shows that social cognitive tests can be used for clinical and cognitive subtyping. This is of potential relevance for treatment.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"30 ","pages":"Article 100264"},"PeriodicalIF":2.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40503557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intact and deficient contextual processing in schizophrenia patients","authors":"Oh-Hyeon Choung ,&nbsp;Dario Gordillo ,&nbsp;Maya Roinishvili ,&nbsp;Andreas Brand ,&nbsp;Michael H. Herzog ,&nbsp;Eka Chkonia","doi":"10.1016/j.scog.2022.100265","DOIUrl":"10.1016/j.scog.2022.100265","url":null,"abstract":"<div><p>Schizophrenia patients are known to have deficits in contextual vision. However, results are often very mixed. In some paradigms, patients do not take the context into account and, hence, perform more veridically than healthy controls. In other paradigms, context deteriorates performance much more strongly in patients compared to healthy controls. These mixed results may be explained by differences in the paradigms as well as by small or biased samples, given the large heterogeneity of patients' deficits. Here, we show that mixed results may also come from idiosyncrasies of the stimuli used because in variants of the same visual paradigm, tested with the same participants, we found intact and deficient processing.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"30 ","pages":"Article 100265"},"PeriodicalIF":2.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b9/a1/main.PMC9477851.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40367110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence of discontinuity between psychosis-risk and non-clinical samples in the neuroanatomical correlates of social function","authors":"Shalaila S. Haas ,&nbsp;Gaelle E. Doucet ,&nbsp;Mathilde Antoniades ,&nbsp;Amirhossein Modabbernia ,&nbsp;Cheryl M. Corcoran ,&nbsp;René S. Kahn ,&nbsp;Joseph Kambeitz ,&nbsp;Lana Kambeitz-Ilankovic ,&nbsp;Stefan Borgwardt ,&nbsp;Paolo Brambilla ,&nbsp;Rachel Upthegrove ,&nbsp;Stephen J. Wood ,&nbsp;Raimo K.R. Salokangas ,&nbsp;Jarmo Hietala ,&nbsp;Eva Meisenzahl ,&nbsp;Nikolaos Koutsouleris ,&nbsp;Sophia Frangou","doi":"10.1016/j.scog.2022.100252","DOIUrl":"10.1016/j.scog.2022.100252","url":null,"abstract":"<div><h3>Objective</h3><p>Social dysfunction is a major feature of clinical-high-risk states for psychosis (CHR-P). Prior research has identified a neuroanatomical pattern associated with impaired social function outcome in CHR-P. The aim of the current study was to test whether social dysfunction in CHR-P is neurobiologically distinct or in a continuum with the lower end of the normal distribution of individual differences in social functioning.</p></div><div><h3>Methods</h3><p>We used a machine learning classifier to test for the presence of a previously validated brain structural pattern associated with impaired social outcome in CHR-P (CHR-outcome-neurosignature) in the neuroimaging profiles of individuals from two non-clinical samples (total n = 1763) and examined its association with social function, psychopathology and cognition.</p></div><div><h3>Results</h3><p>Although the CHR-outcome-neurosignature could be detected in a subset of the non-clinical samples, it was not associated was adverse social outcomes or higher psychopathology levels. However, participants whose neuroanatomical profiles were highly aligned with the CHR-outcome-neurosignature manifested subtle disadvantage in fluid (P_FDR = 0.004) and crystallized intelligence (P_FDR = 0.01), cognitive flexibility (P_FDR = 0.02), inhibitory control (P_FDR = 0.01), working memory (P_FDR = 0.0005), and processing speed (P_FDR = 0.04).</p></div><div><h3>Conclusions</h3><p>We provide evidence of divergence in brain structural underpinnings of social dysfunction derived from a psychosis-risk enriched population when applied to non-clinical samples. This approach appears promising in identifying brain mechanisms bound to psychosis through comparisons of patient populations to non-clinical samples with the same neuroanatomical profiles.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"29 ","pages":"Article 100252"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/04/41/main.PMC8980307.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10734344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decision-making and risk-taking in forensic and non-forensic patients with schizophrenia spectrum disorders: A multicenter European study","authors":"Laura Iozzino ,&nbsp;Nicola Canessa ,&nbsp;Paola Rucci ,&nbsp;Marica Iommi ,&nbsp;Alexander Dvorak ,&nbsp;Janusz Heitzman ,&nbsp;Inga Markiewicz ,&nbsp;Marco Picchioni ,&nbsp;Anna Pilszyk ,&nbsp;Johannes Wancata ,&nbsp;Giovanni de Girolamo","doi":"10.1016/j.scog.2022.100257","DOIUrl":"10.1016/j.scog.2022.100257","url":null,"abstract":"<div><p>Studies of patients with schizophrenia and offenders with severe mental disorders decision-making performance have produced mixed findings. In addition, most earlier studies have assessed decision-making skills in offenders or people with mental disorders, separately, thus neglecting the possible additional contribution of a mental disorder on choice patterns in people who offend.</p><p>This study aimed to fill this gap by comparing risk-taking in patients with schizophrenia spectrum disorders (SSD), with and without a history of serious violent offending assessing whether, and to what extent, risk-taking represents a significant predictor of group membership, controlling for their executive skills, as well as for socio-demographic and clinical characteristics.</p><p>Overall, 115 patients with a primary diagnosis of SSD were recruited: 74 were forensic patients with a lifetime history of severe interpersonal violence and 41 were patients with SSD without such a history. No significant group differences were observed on psychopathological symptoms severity. Forensic generally displayed lower scores than non-forensic patients in all cognitive subtests of the Brief Assessment of Cognition in Schizophrenia (except for the “token motor” and the “digit sequencing” tasks) and on all the six dimensions of the Cambridge Gambling Task, except for “<em>Deliberation time</em>”, in which forensic scored higher than non-forensic patients. “<em>Deliberation time</em>” was also positively, although weakly correlated with “poor impulse control”.</p><p>Identifying those facets of impaired decision-making mostly predicting offenders' behaviour among individuals with mental disorder might inform risk assessment and be targeted in treatment and rehabilitation protocols.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"29 ","pages":"Article 100257"},"PeriodicalIF":2.8,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215001322000221/pdfft?md5=ab2f50484fd4cdd162852e4662999f98&pid=1-s2.0-S2215001322000221-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43457700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}