Schizophrenia Research-Cognition最新文献

{"title":"Psychometric properties of the Social knowledge test (SKT) and the Combined stories test (COST) in people with a schizophrenia spectrum disorder","authors":"Amélie M. Achim ,&nbsp;Elisabeth Thibaudeau ,&nbsp;Frédéric Haesebaert ,&nbsp;Audrey Cayouette ,&nbsp;Caroline Cellard","doi":"10.1016/j.scog.2025.100373","DOIUrl":"10.1016/j.scog.2025.100373","url":null,"abstract":"<div><h3>Background</h3><div>People with schizophrenia spectrum disorders (SSD) often present with impaired social cognition. Among the measures available to assess these deficits, the Combined stories test (COST) and the Social knowledge test (SKT), that respectively target theory of mind (ToM) and social knowledge, have shown promising psychometric properties in prior studies. Test-retest reliability was however only examined in the general population, and the acceptability of these tests was not previously examined. This study aimed to further document the psychometric properties of the COST and the SKT and the acceptability of these tests in people with SSD and community controls (CO).</div></div><div><h3>Methods</h3><div>Forty-four (44) participants with SSD and 49 CO were administered the COST and SKT twice, about 4 weeks apart, and were asked to rate the acceptability of the tests on a 0 (Very unpleasant) to 10 (Very pleasant) point scale at both timepoints.</div></div><div><h3>Results</h3><div>In both groups, the results revealed an excellent inter-rater reliability and a good test-retest reliability for both tests, though the control non-social reasoning measure included in the COST showed poorer test-retest reliability in the SSD group. Some practice effects were observed but the ToM score from the COST and the SKT total score showed no evidence of ceiling effects at either timepoints. The average acceptability scores ranged between 7.8/10 and 8.3/10 for the COST and between 6.8/10 and 7.9/10 for the SKT.</div></div><div><h3>Conclusion</h3><div>The SKT and the COST present with good psychometric properties, representing good options for future studies or for use in clinical practice.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"42 ","pages":"Article 100373"},"PeriodicalIF":2.3,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ADHD and schizophrenia: Mere prodromal variant or homogeneous subgroup?","authors":"J.B. Schulze ,&nbsp;F. Simnacher ,&nbsp;T.J. Müller ,&nbsp;J. Kirchebner ,&nbsp;F. Quatela ,&nbsp;C. Mikutta ,&nbsp;S. Euler ,&nbsp;R. von Känel ,&nbsp;M.P. Günther","doi":"10.1016/j.scog.2025.100374","DOIUrl":"10.1016/j.scog.2025.100374","url":null,"abstract":"<div><h3>Introduction</h3><div>Attention deficit hyperactivity disorder (ADHD) diagnosed in childhood is associated with a relative risk of 4.74 (95 % CI, 4.11–5.46) for developing schizophrenia spectrum disorder (SSD) later in life; if other comorbidities exist the risk is 2.1-fold higher. There is no guideline on treating ADHD in SSD and no research on the effect of this combination on length of inpatient treatment, type of pharmacotherapy and employment status. This study aims to further explore the role of ADHD in SSD.</div></div><div><h3>Methods</h3><div>Latent Class Analysis (LCA) uses no a priori assumptions in testing for homogeneous subgroups within a data sample of 2871 inpatient treatment cases of SSD from three psychiatric hospitals. Data was extracted from case files and statistical reports to the federal statistical office.</div></div><div><h3>Results</h3><div>Two subgroups are identified. One primarily consists of individuals with SSD and ADHD (estimated population size of 3 %). In comparison to the other subgroup with SSD and no ADHD (97 %), these individuals more frequently have other mental comorbidities, especially substance use disorders, are unemployed and about half are administered stimulants. All studied individuals were administered antipsychotics and length of inpatient stay was similar in both subgroups.</div></div><div><h3>Conclusion</h3><div>ADHD and SSD define a subgroup of individuals with specific treatment needs and additional burden of disease. ADHD is more than an initial misdiagnosis or random precursor disease of SSD. Treating psychiatrists seem to frequently administer stimulants.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"42 ","pages":"Article 100374"},"PeriodicalIF":2.3,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144306712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and acceptability of combining cognitive remediation and tDCS in long-term psychiatric clinical care","authors":"Anika Poppe ,&nbsp;Leonie Bais ,&nbsp;Daniëlle van Duin ,&nbsp;Branislava Ćurčić-Blake ,&nbsp;Gerdina Hendrika Maria Pijnenborg ,&nbsp;Lisette van der Meer","doi":"10.1016/j.scog.2025.100358","DOIUrl":"10.1016/j.scog.2025.100358","url":null,"abstract":"<div><h3>Background and hypothesis</h3><div>Cognitive impairments are commonly experienced by individuals with severe mental illness (SMI) and are associated with problems in everyday life. This pragmatic, randomized, controlled, pilot trial explored the acceptability, feasibility, and preliminary effects of cognitive remediation (CR) combined with transcranial direct current stimulation (tDCS) for cognitive and everyday functioning in individuals with SMI in long-term psychiatric clinical care. We hypothesized that combining CR and tDCS is feasible and acceptable to individuals with SMI.</div></div><div><h3>Study design</h3><div>Twenty-four individuals with SMI were randomized to either CR + active tDCS (<em>n</em> = 13) or CR + sham tDCS (<em>n</em> = 11) over 32 sessions (16 weeks). Acceptability was evaluated in semi-structured interviews. Cognitive and everyday functioning were evaluated at baseline, post-16 week waiting period, post-intervention, and 6-months post-intervention.</div></div><div><h3>Study results</h3><div>Overall, participants were positive about the training. Over 60 % of participants successfully finished at least 20 sessions, meeting the predefined criteria for feasibility. CR appeared to yield subjective improvements to participants, significant improvements in cognitive tests post-intervention and at follow-up and improved self-reported negative symptoms at follow-up. Observer-rated everyday functioning and cognition, and subjective cognitive complaints did not change following CR.</div></div><div><h3>Conclusions</h3><div>This study concludes that CR is an acceptable and feasible intervention for individuals with SMI in long-term psychiatric clinical care. The addition of tDCS requires further investigation to ascertain its potential benefits.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"42 ","pages":"Article 100358"},"PeriodicalIF":2.3,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144253501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive changes in schizophrenia before and after illness onset: A meta-analysis examining consistency in measurement tools as a moderator","authors":"Noaz Cohen ,&nbsp;Mark Weiser ,&nbsp;Abraham Reichenberg ,&nbsp;John M. Davis ,&nbsp;Michael Davidson ,&nbsp;Nomi Werbeloff","doi":"10.1016/j.scog.2025.100371","DOIUrl":"10.1016/j.scog.2025.100371","url":null,"abstract":"<div><h3>Background</h3><div>Cognitive impairment, a core feature of schizophrenia, is often evident before the onset of illness. The current study aimed to quantify IQ decline following the onset of illness by conducting a meta-analysis of longitudinal studies that evaluated cognitive functioning both before and after the first psychotic episode. Consistency in measurement tools – i.e. whether the same measurement tool was used at both assessments – was considered a potential moderating variable.</div></div><div><h3>Method</h3><div>Eleven studies were included in the meta-analysis - seven using the same measurement tool at both time-points and four using different tools. In addition, meta-regression explored whether the magnitude of IQ decline was associated with age at baseline.</div></div><div><h3>Results</h3><div>The meta-analysis effect size was −0.343 (95 % CI: −0.503 to −0.184), equivalent to a decrease of 5 IQ points. Use of the same (SMD −0.321, 95 % CI: −0.501 to −0.142) vs different (SMD −0.427, 95 % CI: −0.777 to −0.077) measurement tools was not a moderator of IQ change (<em>p</em> = 0.279). The meta-regression results were not significant (<em>p</em> = 0.544).</div></div><div><h3>Conclusion</h3><div>The current meta-analysis indicates a slight cognitive decline from the premorbid stage to post-onset. The use of different measurement tools yielded a slightly larger effect size and greater heterogeneity, suggesting that employing the same assessment tool could lead to more accurate results. Future longitudinal studies should focus on determining the timeline of cognitive decline.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"41 ","pages":"Article 100371"},"PeriodicalIF":2.3,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144190157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social perception in parents with schizophrenia or bipolar disorder and their adolescent offspring – The Danish High Risk and Resilience Study","authors":"Lotte Veddum ,&nbsp;Anette Faurskov Bundgaard ,&nbsp;Andreas Færgemand Laursen ,&nbsp;Sanciya Mano Perfalk ,&nbsp;Maja Gregersen ,&nbsp;Mette Falkenberg Krantz ,&nbsp;Birgitte Klee Burton ,&nbsp;Camilla Jerlang Christiani ,&nbsp;Ditte Ellersgaard ,&nbsp;Sinnika Birkehøj Rohd ,&nbsp;Marta Schiavon ,&nbsp;Doris Helena Bjarnadóttir Streymá ,&nbsp;Jens Richardt Møllegaard Jepsen ,&nbsp;Kerstin Plessen ,&nbsp;Nicoline Hemager ,&nbsp;Anne Amalie Elgaard Thorup ,&nbsp;Merete Nordentoft ,&nbsp;Ole Mors ,&nbsp;Aja Neergaard Greve","doi":"10.1016/j.scog.2025.100370","DOIUrl":"10.1016/j.scog.2025.100370","url":null,"abstract":"<div><div>Schizophrenia and bipolar disorder are associated with social cognitive impairments, but knowledge on social cognition in offspring of parents with these disorders is sparse. Moreover, investigations of the potential transgenerational transmission of social cognition in at-risk families are lacking. Therefore, we aimed to investigate social perception in parents with schizophrenia or bipolar disorder and their adolescent offspring and population-based controls (PBC).</div><div>This study is part of The Danish High Risk and Resilience Study, a prospective familial high-risk study of families with parental schizophrenia (<em>n</em> = 202) or bipolar disorder (<em>n</em> = 120) and PBC (<em>n</em> = 200). Social perception was assessed with The Awareness of Social Inferences Task, Part 2A, including a total score and the subscales sincere, simple sarcasm, and paradoxical sarcasm.</div><div>Parents with schizophrenia showed poorer performance on the total scale (<em>p</em> &lt; 0.007, <em>d</em> = 0.33) and the paradoxical sarcasm subscale (<em>p</em> &lt; 0.003, <em>d</em> = 0.35) compared with PBC parents. We found no difference between parents with bipolar disorder and PBC parents or between the adolescent offspring. We found no significant interaction effect of familial high-risk status on any association (<em>p</em> ≤ 0.093), but the parents' and their adolescent offspring's social perception was positively and significantly associated on the total scale (<em>p</em> &lt; 0.001), the sincere subscale (<em>p</em> = 0.005), and the simple sarcasm subscale (<em>p</em> = 0.010), but not the paradoxical sarcasm subscale (<em>p</em> = 0.052).</div><div>Our findings of transgenerational transmission of social perception in families with parental schizophrenia or bipolar disorder and PBC call for further longitudinal research to determine how social cognitive deficits are transmitted from parents to their offspring.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"41 ","pages":"Article 100370"},"PeriodicalIF":2.3,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidimensionality of hallucination-like experiences: A factor structure refinement of the Launay-Slade Hallucination Scale","authors":"H. Honcamp ,&nbsp;L.K. Goller ,&nbsp;M. Amorim ,&nbsp;S.X. Duggirala ,&nbsp;J.F. Johnson ,&nbsp;M. Schwartze ,&nbsp;A.P. Pinheiro ,&nbsp;S.A. Kotz","doi":"10.1016/j.scog.2025.100368","DOIUrl":"10.1016/j.scog.2025.100368","url":null,"abstract":"<div><h3>Background</h3><div>Previous research on the multidimensionality of hallucination-like experiences (HLEs) across the psychosis continuum highlights methodological disparities, emphasizing the need for a cautious interpretation of findings and transparent reporting of parameters used in the analysis.</div></div><div><h3>Methods</h3><div>This study aimed to refine the factorial structure of the 16-item Launay-Slade Hallucination Scale (LSHS), enhance methodological clarity, and improve the robustness of LSHS factor solutions. To this end, an Exploratory Factor Analysis (EFA) was performed on a heterogeneous sample (<em>N</em> = 278) with specified parameters (e.g., estimation procedure) that remain true to data characteristics and assumptions underlying EFA.</div></div><div><h3>Results</h3><div>The results revealed a four-factor structure including “Multisensory HLEs”, “Auditory daydreaming”, “Vivid thoughts and inner speech”, and “Personified HLEs”. Our investigation introduces a new factor specific to the perceived presence of another person or another voice. This aligns with theories on self-monitoring difficulties associated with an external attribution bias as hallucination proneness (HP) increases across the continuum.</div></div><div><h3>Conclusion</h3><div>The current results provide an opportunity for investigating neurophysiological and neurobehavioral correlates of HP considering highly differentiated individual profiles of HLEs. Future studies should focus on validating the robustness of the four-factor structure derived from this research across diverse samples of the general population (e.g., different age groups and cultural backgrounds). Specified composite scores underlying HLEs could be of additive value when assessing emerging clinical risk on the psychosis continuum.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"41 ","pages":"Article 100368"},"PeriodicalIF":2.3,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of modifying the pulse width on cognitive side effects with electroconvulsive therapy for schizophrenia","authors":"Qi Si ,&nbsp;Yingbo Dong ,&nbsp;Yuting Li ,&nbsp;Guoxin Xu ,&nbsp;Yilin Tang ,&nbsp;Peiyu Cao ,&nbsp;Congxin Chen ,&nbsp;Fangfang Ren ,&nbsp;Runda Li ,&nbsp;Yuxiu Sui","doi":"10.1016/j.scog.2025.100369","DOIUrl":"10.1016/j.scog.2025.100369","url":null,"abstract":"<div><h3>Background</h3><div>The majority of studies have shown substantially reduced cognitive impairment with ultra-brief pulse (UBP) electroconvulsive therapy (ECT) compared to brief pulse (BP) ECT, though the results remain inconclusive.</div></div><div><h3>Methods</h3><div>This study employed a randomized, double-blind, controlled trial design. A total of 114 patients with schizophrenia (SCZ) were enrolled and received BP ECT (63 participants) or UBP ECT (51 participants). Cognitive function was assessed before and after treatment, with peripheral blood biomarkers and hippocampal magnetic resonance spectroscopy (MRS) data collected concurrently.</div></div><div><h3>Results</h3><div>No significant baseline differences in demographic or clinical characteristics were observed between the two groups. After the end of ECT sessions, the UBP group and BP group respectively showed advantages in the Trail Making Test (TMT) and Hopkins Verbal Learning Test (HVLT). No between-group differences reached statistical significance in other cognitive tests. The homocysteine, prolactin, inducible nitric oxide synthase and left hippocampal myoinositol (MI) levels were significantly elevated in the UBP group than those in the BP group. Multiple linear regression analysis indicated that right hippocampal MI levels were positively correlated with TMT scores.</div></div><div><h3>Conclusion</h3><div>There are no significant differences in efficacy between UBP ECT at high-dosage and BP ECT, and further research is required to determine whether this modality can reduce cognitive impairment after treatment.</div></div><div><h3>Clinical trial registration</h3><div><span><span>https://www.chictr.org.cn/showproj.html?proj=243964</span><svg><path></path></svg></span>, registration number: ChiCTR2400091601.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"41 ","pages":"Article 100369"},"PeriodicalIF":2.3,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A transdiagnostic approach to understanding neural responsivity to reward and its links to social motivation","authors":"Amy M. Jimenez ,&nbsp;Samuel J. Abplanalp ,&nbsp;Naomi I. Eisenberger ,&nbsp;William P. Horan ,&nbsp;Junghee Lee ,&nbsp;Amanda McCleery ,&nbsp;Ana Ceci Myers ,&nbsp;David J. Miklowitz ,&nbsp;Eric A. Reavis ,&nbsp;L. Felice Reddy ,&nbsp;Jonathan K. Wynn ,&nbsp;Michael F. Green","doi":"10.1016/j.scog.2025.100367","DOIUrl":"10.1016/j.scog.2025.100367","url":null,"abstract":"<div><div>Schizophrenia (SZ) and bipolar disorder (BD) are characterized by social impairments. Social impairment also occurs in the general community. Across clinical and nonclinical groups social impairment may be related to deficits in social approach and/or social avoidance motivation. However, the neural basis of social motivation deficits in SZ and BD is not well understood, nor is it known if they reflect features of the illness or are secondary to other factors such as social isolation. To fill these knowledge gaps, 31 individuals with SZ, 27 with BD, and 42 community comparisons (CCs) completed a team-based task during fMRI in which positive and negative feedback was provided by pictures of teammates or opponents. Importantly, the CC group was enriched for self-reported social isolation. fMRI analyses in five key regions of interest (ROIs; ventral striatum, orbital frontal cortex, insula, dorsal anterior cingulate cortex, amygdala), secondary whole-brain analyses, and associations between ROI activity and social approach/avoidance motivation were performed. Across groups, ventral striatum and amygdala showed greater activation to positive versus negative feedback. In SZ, ventral striatum activity to positive feedback was correlated with social approach motivation. In CCs, amygdala activity during negative feedback was correlated with social avoidance motivation. Whole-brain analyses revealed greater activation in BD compared to SZ and CCs in fronto-parietal regions when feedback was provided by an opponent. Findings support disturbed reward sensitivity as a core component of poor social approach motivation in SZ and offer avenues for future research into neural mechanisms underlying social impairment in BD and the general community.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"41 ","pages":"Article 100367"},"PeriodicalIF":2.3,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144107714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The glare illusion in individuals with schizophrenia","authors":"Hideki Tamura ,&nbsp;Aiko Hoshino","doi":"10.1016/j.scog.2025.100366","DOIUrl":"10.1016/j.scog.2025.100366","url":null,"abstract":"<div><div>Individuals with schizophrenia are known to display unique reactions to visual illusions, and prior research has indicated a potential link between their increased susceptibility to geometric illusions and specific symptom profiles. While various illusory experiences have been examined among individuals with schizophrenia, their responses to brightness-related illusions remain poorly understood. In this study, we investigated how individuals with schizophrenia perceive the glare illusion, in which the apparent brightness of the central region is increased. A total of 30 patients with schizophrenia and 34 control participants were recruited. During each trial, a glare or control image (standard stimulus) was presented alongside a control image (comparison stimulus) with one of seven luminance levels. In the glare condition, the standard stimulus was a glare image; in the control condition, two control images were presented, but only the luminance of the comparison stimulus varied. The participants were asked to judge which central region appeared brighter. The results revealed that individuals with schizophrenia exhibited greater susceptibility to the glare illusion than did the control participants. However, no significant associations were found between susceptibility to the glare illusion and scores assessing symptom severity. These findings suggest that differences in visual processing in patients with schizophrenia may increase their susceptibility to brightness illusions, although this phenomenon is independent of symptom characteristics. This information may provide a basis for exploring illusion susceptibility as a potential behavioral index for distinguishing between individuals with schizophrenia and control participants.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"41 ","pages":"Article 100366"},"PeriodicalIF":2.3,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144089452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognition as a predictor of social network size and early communication in clinically high risk for psychosis individuals","authors":"Nashya Linares ,&nbsp;Danielle N. Pratt ,&nbsp;Katherine S.F. Damme ,&nbsp;Vijay A. Mittal","doi":"10.1016/j.scog.2025.100365","DOIUrl":"10.1016/j.scog.2025.100365","url":null,"abstract":"<div><div>Social networks provide critical support, yet individuals at clinical high-risk for psychosis (CHR) often experience deficits in social functioning and have smaller networks compared to healthy controls (HCs). Cognitive impairment, a hallmark characteristic of this group, may be associated with these challenges. This study is the first investigation into the relationships between general and specific domains of cognition and social network and communication abilities in people at CHR. The sample included 91 participants (HC = 43, CHR = 48) with complete cognitive and social network assessments from the same visit, with additional analyses including guardian ratings of social responsiveness and communication. Cognitive ability was significantly associated with social network size in both groups (b = 0.38, <em>p</em> &lt; .0001), with significant contributions from working memory (b = 0.29, <em>p</em> = .004), speed of processing (b = 0.23, <em>p</em> = 002), verbal learning (b = 0.24, <em>p</em> = .007), and social cognition (b = 0.25, <em>p</em> = .012). Higher scores on cognitive functioning correlated with better social reciprocity (b = 1.28, <em>p</em> = .009) and fewer communication difficulties (b = 0.25, <em>p</em> &lt; .002). Processing speed was particularly relevant to both social responsiveness (b = 0.88, <em>p</em> &lt; .022) and communication difficulties (b = 0.12, <em>p</em> &lt; .03). An interaction effect revealed that associations between cognitive ability on communication skills were more pronounced in CHR individuals compared to HCs (b = 0.26, <em>p</em> &lt; .037). These findings underscore the potential role of specific cognitive domains, such as processing speed, in social functioning among CHR individuals. Future research should examine the directionality of these relationships to better understand underlying mechanisms of social functioning impairments and inform treatment development.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"41 ","pages":"Article 100365"},"PeriodicalIF":2.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143917527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}