HardwareXPub Date : 2025-12-01Epub Date: 2025-09-19DOI: 10.1016/j.ohx.2025.e00702
Mottaghi Maryam , M. Pearce Joshua
{"title":"Open source inert gas glove box","authors":"Mottaghi Maryam , M. Pearce Joshua","doi":"10.1016/j.ohx.2025.e00702","DOIUrl":"10.1016/j.ohx.2025.e00702","url":null,"abstract":"<div><div>A glove box is a controlled environment used for a wide range of scientific experiments. While glove boxes provide significant advantages, their high economic costs ranging from over $1,000 to over $15,000 limits their accessibility in under-resourced labs. There are lower-cost DIY designs available on the internet, but they have not been well characterized nor validated. To overcome these limitations, in this study, an open source glove box design is developed for scientific applications using readily available components and digital distributed manufacturing using open-source RepRap-class 3D printers. The ability of the glove box to hold an inert atmosphere is quantified using an oxygen analyzer. The open source glove box can be customized to the dimensions of the user and the volume of the experiment. The design also enables the use of customizable transfer chambers that can be adjusted based on the scientific application. The open source glove box is built from a low-cost enclosure while preventing contamination. The highly portable device can reduce oxygen down to 19 ppm using an inert gas. The economic savings of the validated device compared to proprietary systems is over 95 %.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00702"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-10-02DOI: 10.1016/j.ohx.2025.e00712
Daniel SW Katz , Kacper Sobieraj , Christopher Karounos , Stuart A Batterman
{"title":"Rotapollen Sampler: An affordable, portable, and programmable rotorod-style device for measuring airborne pollen concentrations","authors":"Daniel SW Katz , Kacper Sobieraj , Christopher Karounos , Stuart A Batterman","doi":"10.1016/j.ohx.2025.e00712","DOIUrl":"10.1016/j.ohx.2025.e00712","url":null,"abstract":"<div><div>We present designs for a rotorod-style device for sampling airborne pollen and other particulates >10 µm. This device is affordable ($118 USD for the first individual sampler with an incremental cost of $48 for the 10th sampler built) and collects data very similar to commercial pollen measurement devices (that cost $1300−$6000 per sampler). The design is portable, battery operated, programmable, and includes retracting sampling rods to prevent passive sampling between periods of active sampling and can include a rain shield to allow deployment in inclement weather. The main sampler is 135 × 75 × 93 mm and weighs 185 g, allowing for easy deployment on portable tripods at breathing height. As with other rotorod-style devices, active sampling time during normal pollen concentrations is limited to 1 h, but this sampling activity can be distributed across periods ranging up to several days; the timing of sampling is programmable through a simple and easily modifiable Arduino script. This validated sampler (r > 0.99 compared to a commercial rotorod-style device) is field tested and results have been published in several peer-reviewed publications. The Rotapollen Sampler is well suited for investigations of airborne pollen concentrations, and especially for sampling campaigns that simultaneously collect measurements in multiple locations, such as those that seek to understand spatial heterogeneity in airborne pollen concentrations.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00712"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145416974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-11-24DOI: 10.1016/j.ohx.2025.e00723
Abinash Sahoo, Ryan D. DeBoskey, Venkateswaran Narayanaswamy
{"title":"Low-cost open-source camera view splitter (quadscope) for flow diagnostics","authors":"Abinash Sahoo, Ryan D. DeBoskey, Venkateswaran Narayanaswamy","doi":"10.1016/j.ohx.2025.e00723","DOIUrl":"10.1016/j.ohx.2025.e00723","url":null,"abstract":"<div><div>Camera view splitters use optical engineering to cast multiple images of a single target onto a single camera. For experiments in fluid dynamics, the ability to perform multivariate and multidimensional measurements is key to effectively studying complex thermofluidic phenomena. Generating multiple target views onto a single camera is a good way to reduce system costs by using fewer cameras. Currently, view splitting requires the purchase of expensive commercial lenses or the in-house design and fabrication of custom components, hindering the pace of research and development. Here, we provide an open-source design for a low-cost, general-purpose view splitter, providing up to four views per camera. All custom parts for the assembly are provided, which are designed for easy integration with standard optical components. Additional files are included for different view splitter orientations (designed for tomography) and the optional integration with spectral filtering. Characterization experiments were performed at multiple object distances to determine changes in image mapping quality, parallax angles, pixel density, and field-of-view (FOV). Validation is performed on a non-premixed methane/air flame, demonstrating the ability of the view splitter to perform simultaneous high-speed imaging and quantitative measurement in a practical system. This assembly has the potential to democratize access to advanced imaging capability and accelerate progress in the broader diagnostics community.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00723"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145614678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-09-19DOI: 10.1016/j.ohx.2025.e00705
Maj-Britt Buchholz , Nils Bessler , Anne C. Rios
{"title":"AnyBio – An easy off-the-shelf masked stereolithography bioprinter conversion combined with radical-scavenging strategies","authors":"Maj-Britt Buchholz , Nils Bessler , Anne C. Rios","doi":"10.1016/j.ohx.2025.e00705","DOIUrl":"10.1016/j.ohx.2025.e00705","url":null,"abstract":"<div><div>Over the last two decades 3D bioprinting has gained momentum to fabricate tissue mimicking constructs serving as tissue models, animal-free drug screening platforms and tissue replacements for regenerative medicine. Recently, the focus has shifted towards the development of light-based bioprinting methods due to its high accuracy and absence of nozzle-induced shear stress on printed cells. However, light-based bioprinting equipment can be costly and photo-sensitive materials difficult to optimize. In this work, we present the conversion of a masked stereolithography printer into a heated, humidified, and easily sterilizable bioprinter, with minimal financial investment (<350 € including purchase of the printer). We provide instructions on how to optimize bioinks and printing conditions and explore novel bioresin additives utilizing cell-friendly photon absorption and radical scavenging strategies. As a proof of concept, we demonstrate the compatibility of our method for the ability of our printer to produce complex and perfusable architectures as well as successful cell printing with high post-printing viability. With this we aim to contribute to accessibility of both hardware and protocols to easily implement bioprinting with minimal barriers.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00705"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145320701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-09-11DOI: 10.1016/j.ohx.2025.e00696
James Cushway , J. Geoffrey Chase , Thomas Desaive , Liam Murphy , Isaac L. Flett , Geoffrey M. Shaw
{"title":"A novel clinical data acquisition device: Towards real time cardiovascular modelling in the ICU","authors":"James Cushway , J. Geoffrey Chase , Thomas Desaive , Liam Murphy , Isaac L. Flett , Geoffrey M. Shaw","doi":"10.1016/j.ohx.2025.e00696","DOIUrl":"10.1016/j.ohx.2025.e00696","url":null,"abstract":"<div><div>Patient specific cardiovascular system models have the potential to provide far greater insights into patient conditions than is currently possible in the intensive care unit (ICU). Access to haemodynamic data is imperative for the introduction and validation of these models for model-based care in the ICU. However, current bedside machines are proprietary systems and do not allow access to any data without potentially prohibitive cost, creating a barrier to research and advancements in bedside care. This work presents a novel, low-cost data capture system which allows real time capture of haemodynamic measurements, as well as fluid infusion rates in the ICU. The system consists of an Arduino controlled data capture unit, an adaptor for connecting to existing bedside pressure sensors, and a Python based application which displays and records data sent from the data capture system over a USB serial connection. The total system is highly customizable if needed, and costs a total of NZ$200.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00696"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145061232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-09-29DOI: 10.1016/j.ohx.2025.e00707
Francesca Gallaway, Henry W. Hall, Matthew Walker, Chloe Tattersfield, Stephanie Post, Jessica Fitzjohn, Cong Zhou, J.Geoffery Chase
{"title":"Silicone Breast Phantoms for use with Digital Imaging Elasto-Tomography Breast Cancer Screening","authors":"Francesca Gallaway, Henry W. Hall, Matthew Walker, Chloe Tattersfield, Stephanie Post, Jessica Fitzjohn, Cong Zhou, J.Geoffery Chase","doi":"10.1016/j.ohx.2025.e00707","DOIUrl":"10.1016/j.ohx.2025.e00707","url":null,"abstract":"<div><div>Breast cancer is the most common form of cancer and has the highest mortality rate among all types of cancer. The current best method to prevent deaths from breast cancer is by early detection. The gold standard for breast cancer detection screening is X-ray mammography. However, it has several limitations, including invasive radiation exposure and poor performance in younger women with dense breast tissue. Digital Imaging Elasto-Tomography is a novel breast cancer screening device using mechanical vibrations and computer vision algorithms to determine the actuated breast tissue surface motion and, from them, infer the elastic properties of underlying breast tissue. It leverages the 400-1000% stiffness contrast between health breast tissues and tumor tissues.</div><div>To further develop this device breast phantoms are required to test device software, hardware, use, and to quantify diagnostic algorithm performance on repeatable phantom test subjects. These phantoms need to have elastic properties appropriately representing realistic breast tissues and tumor tissues. The production of both asymmetric, realistically shaped and symmetric breast phantoms are detailed. Each of these phantoms is comprised of different silicone compositions representing different tissues, including a skin layer, healthy fat tissue, and cancerous tumour tissue. Several tests were performed to validate these phantoms, including compression testing to determine the elastic modulus and its location within reported human tissue stiffness value ranges.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00707"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145320698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-10-08DOI: 10.1016/j.ohx.2025.e00713
Julius Korsimaa, Martin Weber, Edward Hæggström, Ari Salmi
{"title":"Wireless trigger distribution with nanosecond jitter based on ultra-wideband transceiver modules","authors":"Julius Korsimaa, Martin Weber, Edward Hæggström, Ari Salmi","doi":"10.1016/j.ohx.2025.e00713","DOIUrl":"10.1016/j.ohx.2025.e00713","url":null,"abstract":"<div><div>Wireless sensor networks require time synchronization to operate in a coordinated manner. Synchronizing the clock of each sensor node by using a network protocol can be sufficient for millisecond accuracy, whereas precision in the range of nanoseconds can be achieved by using Global Navigation Satellite System (GNSS) receivers.</div><div>Unfortunately, the use of GNSS signals requires an unobstructed view of the sky, and thus they cannot be used indoors or underground. Additionally, GNSS is susceptible to jamming and spoofing, and their use depends on the availability of global infrastructure.</div><div>To address these limitations, we propose a trigger signal distribution system based on the DWM1000 IEEE 802.15.4-2011 ultra-wideband transceiver module. A network of two or more modules can be configured to wirelessly distribute trigger signals with a typical jitter of less than <span><math><mo>±</mo></math></span>4<!--> <!-->ns.</div><div>This approach can be applied in, e.g., structural health monitoring with ultrasonic guided waves. We used the solution to coordinate signal transmission and reception in a wireless sensor network.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00713"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145320699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-10-19DOI: 10.1016/j.ohx.2025.e00717
A. Escobar-Díaz , A. Villarreal , B. Zárate-Nicolas , A. Rojas-Olivos
{"title":"System design for monitoring REDOX potential in treated water using an ORP sensor","authors":"A. Escobar-Díaz , A. Villarreal , B. Zárate-Nicolas , A. Rojas-Olivos","doi":"10.1016/j.ohx.2025.e00717","DOIUrl":"10.1016/j.ohx.2025.e00717","url":null,"abstract":"<div><div>Electrodes that measure the oxidation–reduction potential (ORP) assess the relationship between oxidized and reduced substances that may exist in water disinfection processes. This work presents the implementation and characterization of an ORP measurement system using the Atlas Scientific ORP sensor, integrated with an Arduino R4 development board as the control and data transmission unit. The main objective is to develop an economical, fast, and reliable solution for the continuous monitoring of the bacteriological quality of water in a wastewater treatment plant (WWTP). The system operates in real time, transmitting information to remote platforms. The manufacturing and integration stages of the system, as well as its calibration and experimental validation, are described. The results indicate that a properly calibrated sensor provides accurate measurements, making it a viable and cost-effective alternative to traditional laboratory equipment or bacteriological analyses that require long processing times. Additionally, by monitoring the ORP variable in a WWTP, alerts can be generated for variations related to microbial load in the wastewater treatment process, enabling immediate corrective actions before discharge into surface water bodies.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00717"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145362741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-11-17DOI: 10.1016/j.ohx.2025.e00715
Scott Mayberry, Jinzhi Cai, Ruochu Yang, Junkai Wang, Fumin Zhang
{"title":"An open-source underwater robotics platform for aquatic research & exploration","authors":"Scott Mayberry, Jinzhi Cai, Ruochu Yang, Junkai Wang, Fumin Zhang","doi":"10.1016/j.ohx.2025.e00715","DOIUrl":"10.1016/j.ohx.2025.e00715","url":null,"abstract":"<div><div>Underwater research is often constrained by the specialized expertise, high costs, and dedicated facilities required for traditional aquatic experiments, limiting participation from smaller research groups. In response, we introduce an open-source miniature underwater robot (MUR) platform that broadens access to aquatic research and exploration while simplifying experimental implementation. Built on a fully networked ROS ecosystem, our platform integrates advanced sensing, control, and versatile communication capabilities to support real-time data acquisition and sensor fusion. Its modular 5-degree-of-freedom propulsion system enables precise position, yaw, and roll control, with passive pitch stability through neutral buoyancy supporting steady station-keeping and dynamic trajectory tracking. Equipped with multiple cameras, the system facilitates advanced perception tasks essential for complex underwater operations. Moreover, WiFi, radio, and high-speed Ethernet tethering ensure communication in shallow water environments, enabling both autonomous operation and tethered deployments. This open, modular architecture reduces barriers to underwater research while promoting collaborative innovation and establishing a shared research infrastructure for marine science and robotics.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00715"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145568247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-09-17DOI: 10.1016/j.ohx.2025.e00704
Jhonatan A. Gutierrez-Rivera , Andres F. Roca-Arroyo , David A. Castilla-Casadiego , Alberto Albis
{"title":"Development of a low-cost electrospinning system with a bidirectional collector for uniform nanofibrous membranes","authors":"Jhonatan A. Gutierrez-Rivera , Andres F. Roca-Arroyo , David A. Castilla-Casadiego , Alberto Albis","doi":"10.1016/j.ohx.2025.e00704","DOIUrl":"10.1016/j.ohx.2025.e00704","url":null,"abstract":"<div><div>The electrospinning process is a widely used technique for the fabrication of membranes with nanometric fibers, employing polymeric materials such as polyvinylidene fluoride and polycaprolactone. The shape of the fiber collector, whether static or rotating, significantly impacts membrane uniformity. Although rotating drum collectors are the most used, they exhibit drawbacks such as uneven fiber accumulation. Current solutions, which favor rotating over static collectors, tend to be more expensive and complex. This article presents an electrospinning setup that utilizes a flat acrylic plate with bidirectional movement along the X and Y axes, enhancing fiber collection and membrane uniformity. This design improves process efficiency, fiber reproducibility, and system scalability. Polystyrene electrospun nanofibrous membranes were fabricated, and their average fiber diameter and pore size were analyzed, demonstrating the system’s capability to produce micro- and nanometric fibers.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00704"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145118885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}