HardwareXPub Date : 2024-01-24DOI: 10.1016/j.ohx.2024.e00510
Domenic J. Cordova , Angel A. Rodriguez , Sabrina C. Woodward , Cody O. Crosby
{"title":"The Enderstruder: An accessible open-source syringe extruder compatible with Ender series 3D printers","authors":"Domenic J. Cordova , Angel A. Rodriguez , Sabrina C. Woodward , Cody O. Crosby","doi":"10.1016/j.ohx.2024.e00510","DOIUrl":"https://doi.org/10.1016/j.ohx.2024.e00510","url":null,"abstract":"<div><p>Bioprinting has enabled the precise spatiotemporal deposition of cells and biomaterials, opening new avenues of research in tissue engineering and regenerative medicine. Although several open-source syringe extruder adaptations for bioprinters have been published and adopted by end users, only one has been specifically adapted for the Ender series, an affordable and open-source line of thermoplastic 3D printers. Here, we introduce the Enderstruder, a cost-effective extruder attachment that uses a standard 10 mL BD syringe, positions the stepper motor at the level of the gantry, enhances x-axis stability with a linear rail, and uses the originally included stepper motor, resulting in reduced cost and simplified assembly. Furthermore, we present an iterative process to fine-tune printing profiles for high-viscosity biomaterial inks. To facilitate the implementation of our work by other researchers, we provide fully editable Cura profiles for five commonly used biomaterials. Using these five materials to validate and characterize our design, we employ the Enderstruder to print established calibration patterns and complex shapes. By presenting the Enderstruder and its iterative development process, this study contributes to the growing repository of open-source bioprinting solutions, fostering greater accessibility and affordability for researchers in tissue engineering.</p></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S246806722400004X/pdfft?md5=e227e52c8fd2a35dfc8a968c47f3fee0&pid=1-s2.0-S246806722400004X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139674616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2024-01-24DOI: 10.1016/j.ohx.2024.e00507
Zhiyuan Yu , Shengwen Guo
{"title":"A low-cost, wireless, 4-channel EEG measurement system used in virtual reality environments","authors":"Zhiyuan Yu , Shengwen Guo","doi":"10.1016/j.ohx.2024.e00507","DOIUrl":"10.1016/j.ohx.2024.e00507","url":null,"abstract":"<div><p>The combination of Virtual Reality (VR) technology and Electroencephalography (EEG) measurements has shown tremendous potential in the fields of psychology and neuroscience research. However, the majority of EEG measurement devices currently available are expensive, bulky, uncomfortable to wear, and difficult to integrate with VR headsets. These limitations have hindered the development of related research fields. This study describes a low-cost (60.07 USD), small-sized, wireless, high-precision, low-power consumption 4-channel EEG measurement system (NeuroVista) for frontal area EEG measurements, which can be used with a VR headset, enabling EEG measurements in VR environments. The system has an input-referred noise of less than 0.9480 <span><math><mrow><mi>μ</mi><mi>V</mi><mi>r</mi><mi>m</mi><mi>s</mi></mrow></math></span>, a common mode rejection ratio of over 96 dB, a measurement resolution of less than 0.1 <span><math><mrow><mi>μ</mi><mi>V</mi></mrow></math></span>, a bandwidth of 0.5 ∼ 45 Hz, and works at a sampling rate of 250 Hz. It also supports metal dry electrodes and includes a built-in analog bandpass filter, right-leg drive circuit, and built-in digital lowpass filter and notch filter, which can reduce noise during measurement. Researchers can reconstruct the electrode system to measure regions of interest according to their needs.</p></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468067224000014/pdfft?md5=49b9e4de3c44905e67632156492470c4&pid=1-s2.0-S2468067224000014-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139635652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2024-01-23DOI: 10.1016/j.ohx.2024.e00511
Andrea Bianchi , Kongpyung (Justin) Moon , Artem Dementyev , Seungwoo Je
{"title":"BlinkBoard: Guiding and monitoring circuit assembly for synchronous and remote physical computing education","authors":"Andrea Bianchi , Kongpyung (Justin) Moon , Artem Dementyev , Seungwoo Je","doi":"10.1016/j.ohx.2024.e00511","DOIUrl":"10.1016/j.ohx.2024.e00511","url":null,"abstract":"<div><p>Motivated by the necessity of guiding and monitoring students when assembling electronic circuits during in-class activities, we propose <em>BlinkBoard</em>, an augmented breadboard that enhances synchronous and remote physical computing classes. <em>BlinkBoard</em> uses LEDs placed on each row of a breadboard to guide, via four distinct blinking patterns, how to place and connect components and wires. It also uses a set of Input/Output pins to sense voltage levels or to generate voltage output at user-specified rows. Our hardware uses an open protocol of JSON commands and responses that can be used directly via a command line interface to control the hardware. Alternatively, these commands can be issued within a front-end graphical application hosted on a computer for a more user-friendly interface, and to ensure bidirectional and real-time communication between the instructor’s guiding and monitoring panel, and all the students’ remote <em>BlinkBoards</em>. The <em>BlinkBoard</em> hardware is affordable and simple, partially due to a customized circuit configured via a hardware description language that handles the LEDs’ patterns with minimal load on the Arduino microcontroller. Finally, we briefly show <em>BlinkBoard</em> in use during a workshop with high-school students and an undergraduate design course.</p></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468067224000051/pdfft?md5=0d16d40823a7147778fbf5dfad225599&pid=1-s2.0-S2468067224000051-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139631403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2023-12-21DOI: 10.1016/j.ohx.2023.e00505
Erin Heeschen , Elena DeLucia , Yilmaz Arin Manav , Daisy Roberts , Benyamin Davaji , Magda H. Barecka
{"title":"Low cost 3D printable flow reactors for electrochemistry","authors":"Erin Heeschen , Elena DeLucia , Yilmaz Arin Manav , Daisy Roberts , Benyamin Davaji , Magda H. Barecka","doi":"10.1016/j.ohx.2023.e00505","DOIUrl":"10.1016/j.ohx.2023.e00505","url":null,"abstract":"<div><p>Transition to carbon neutrality requires the development of more sustainable pathways to synthesize the next generation of chemical building blocks. Electrochemistry is a promising pathway to achieve this goal, as it allows for the use of renewable energy to drive chemical transformations. While the electroreduction of carbon dioxide (CO<sub>2</sub>) and hydrogen evolution are attracting significant research interest, fundamental challenges exist in moving the research focus toward performing these reactions on scales relevant to industrial applications. To bridge this gap, we aim to facilitate researchers' access to flow reactors, which allow the characterization of electrochemical transformations under conditions closer to those deployed in the industry. Here, we provide a 3D-printable flow cell design (manufacturing cost < $5), which consists of several plates, offering a customizable alternative to commercially available flow reactors (cost > $6,000). The proposed design and detailed build instructions allow the performance of a wide variety of chemical reactions in flow, including gas and liquid phase electroreduction, electro(less)plating, and photoelectrochemical reactions, providing researchers with more flexibility and control over their experiments. By offering an accessible, low-cost reactor alternative, we reduce the barriers to performing research on sustainable electrochemistry, supporting the global efforts necessary to realize the paradigm shift in chemical manufacturing.</p></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468067223001128/pdfft?md5=65c9d9c3e9609d51e755aa78794ba66c&pid=1-s2.0-S2468067223001128-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139020569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2023-12-21DOI: 10.1016/j.ohx.2023.e00504
Weilin Ma
{"title":"Open STM: A low-cost scanning tunneling microscope with a fast approach method","authors":"Weilin Ma","doi":"10.1016/j.ohx.2023.e00504","DOIUrl":"10.1016/j.ohx.2023.e00504","url":null,"abstract":"<div><p>In this study, we have developed an low-cost scanning tunneling microscope (STM) cost of 300 USD or 2000 CNY. The microscope is suitable for educational purposes and low-demand research imaging at the nanometer level. The microscope's motion components and scanner are controlled using piezoelectric materials, avoiding the thermal drift associated with traditional motor control. Our tip approach algorithm, which considers the capacitance and friction characteristics during piezoelectric slider movement, has reduced the time required for sample loading to establish tunneling current to approximately 1 min. The physical dimensions of the microscope body are 45 × 45 × 31.5 mm (W × L × H), and the control voltage does not exceed 15 V, ensuring the safety of operators, particularly those with limited experience. During performance verification, we conducted a scanning tunneling scan on a Highly Oriented Pyrolytic Graphite (HOPG) sample, utilizing bias voltages of 50 mV and 60 mV, resulting in clear observations of the atomic features of HOPG within the STM pattern.</p></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468067223001116/pdfft?md5=1c4d6d32366fdf992abad1cfdc37d94a&pid=1-s2.0-S2468067223001116-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139321422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2023-12-20DOI: 10.1016/j.ohx.2023.e00506
Stefan Herrmann , Lukas T. Hirschwald , Karl H. Heidmann , John Linkhorst , Matthias Wessling
{"title":"Lab-scale tubular LED UV reactor for continuous photocatalysis","authors":"Stefan Herrmann , Lukas T. Hirschwald , Karl H. Heidmann , John Linkhorst , Matthias Wessling","doi":"10.1016/j.ohx.2023.e00506","DOIUrl":"10.1016/j.ohx.2023.e00506","url":null,"abstract":"<div><p>Photocatalytic water treatment is considered a promising technique to prevent micropollutants from entering the environment. However, no off-the-shelf UV reactors on lab scale are available to study new processes and photocatalysts. In this study, we present a tubular UV reactor equipped with 30 UV-LEDs, emitting UV light at 367 nm and a total radiant flux of 42<!--> <!-->W. The UV reactor has an irradiated length of 300 mm and can host any transparent chemical reactor on the inside with a maximum diameter of 28 mm. The device is optimized for lab experiments with total dimensions of just 334 mm x 193 mm x 172 mm. Besides water treatment, a broad range of other photochemical and photocatalytic experiments can be performed with the reactor. Two identical UV reactors have been built and are successfully used for photocatalytic water treatment experiments. The degradation of methylene blue with TiO<sub>2</sub> as photocatalyst was studied to validate the UV reactor. Furthermore, photocatalytic and hybrid processes were conducted in the UV reactor to degrade a broad range of pharmaceutical micropollutants.</p></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S246806722300113X/pdfft?md5=e9a404e9af7789e2f42104c7c984aa54&pid=1-s2.0-S246806722300113X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139013513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2023-12-12DOI: 10.1016/j.ohx.2023.e00499
Dylan J. Terstege, Jonathan R. Epp
{"title":"PAW, a cost-effective and open-source alternative to commercial rodent running wheels","authors":"Dylan J. Terstege, Jonathan R. Epp","doi":"10.1016/j.ohx.2023.e00499","DOIUrl":"10.1016/j.ohx.2023.e00499","url":null,"abstract":"<div><p>Voluntary wheel running is a common measure of general activity in many rodent models across neuroscience and physiology. However, current commercial wheel monitoring systems can be cost-prohibitive to many investigators, with many of these systems requiring investments of thousands of dollars. In recent years, several open-source alternatives have been developed, and while these tools are much more cost effective than commercial system, they often lack the flexibility to be applied to a wide variety of projects. Here, we have developed PAW, a 3D Printable Arduino-based Wheel logger. PAW is wireless, fully self-contained, easy to assemble, and all components necessary for its production can be obtained for only $75 CAD. Furthermore, with its compact internal electronics, the 3D printed casing can be easily modified to be used with a wide variety of running wheel designs for a wide variety of rodent species. Data recorded with the PAW system shows circadian patterns of activity which is expected from mice and is consistent with results found in the literature. Altogether, PAW is a flexible, low-cost system that can be beneficial to a broad range of researchers who study rodent models.</p></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468067223001062/pdfft?md5=40497daec4f0994eba40fda7268be810&pid=1-s2.0-S2468067223001062-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139017015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Affordable lab-scale electrospinning setup with interchangeable collectors for targeted fiber formation","authors":"Alexi Switz , Aditi Mishra , Katrina Jabech , Anamika Prasad","doi":"10.1016/j.ohx.2023.e00501","DOIUrl":"https://doi.org/10.1016/j.ohx.2023.e00501","url":null,"abstract":"<div><p>The electrospinning method is increasingly in demand due to its capability to produce fibers in the nanometer to micrometer range, with applications in diverse fields including biomedical, filtration, energy storage, and sensing. Many of these applications demand control over fiber layout and diameter. However, a standard flat plate collector yields random fibers with limited control over diameter and density. Other viable solutions offering a higher level of control are either scarce or substantially expensive, impeding the accessibility of this vital technique. This study addresses the challenge by designing an affordable laboratory-scale electrospinning setup with interchangeable collectors, enabling the creation of targeted fibers from random, aligned, and coiled. The collectors include the standard flat plate and two additional designs, which are a rotating drum and a spinneret tip collector. The rotating drum collector has adjustable speed control to collect aligned fibers and exhibits stability even at high rotational speeds. The spinneret tip collector was designed to produce helically coiled fibers. The setup was validated by directed fiber formation using polycaprolactone (PCL), a biodegradable and FDA-approved polymer. Overall, the uniqueness of the design lies in its affordability, modifiability, and replicability using readily available materials, thus extending the reach of the electrospinning technique.</p></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468067223001086/pdfft?md5=864109d5be8bd2d962ff34d79998994c&pid=1-s2.0-S2468067223001086-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138769553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2023-12-12DOI: 10.1016/j.ohx.2023.e00500
Muhammad Farooq , Muhammad Riaz ur Rehman , Patricia Vazquez , William Wijns , Atif Shahzad , Marcin J. Kraśny
{"title":"Open-source controller for dynamic cardiovascular models","authors":"Muhammad Farooq , Muhammad Riaz ur Rehman , Patricia Vazquez , William Wijns , Atif Shahzad , Marcin J. Kraśny","doi":"10.1016/j.ohx.2023.e00500","DOIUrl":"10.1016/j.ohx.2023.e00500","url":null,"abstract":"<div><p>Cardiovascular pressure sensors require dedicated, reliable, and customisable performance testing equipment. Devices available on the market, such as pulsatile pumps and pulse multipliers, offer limited adaptability to the needs of pressure sensor testing or are highly complex tools designed for other purposes. Therefore, there is a strong need to provide an adaptable and versatile device for characterisation during prototype development, prior to animal model testing. Early development requires detailed characterisation of a sensor performance in a realistic environmental scenario. To address this need, we adapted an off-the-shelf pressure chamber with a custom Arduino-based controller to achieve a rapid change in pressure that simulates the pulsatile profile of human blood pressure. The system is a highly customisable tool, and we have experimentally shown that it works successfully in a wide range of pressures from 30 mmHg to 400 mmHg with a resolution of 2 mmHg. By adjusting the chamber volume using a water balloon, we achieved a cycle rate of up to 120 beats per minute. The device can be operated directly from the Arduino IDE or with a customised graphical user interface developed by our research group. The proposed system is intended to assist other researchers in the development of industrial and biomedical pressure sensors.</p></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2468067223001074/pdfft?md5=3e38158cf6a2b9be99df9221ffc21b6c&pid=1-s2.0-S2468067223001074-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139021572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}