HardwareXPub Date : 2025-12-01Epub Date: 2025-11-12DOI: 10.1016/j.ohx.2025.e00721
Giovanni Barbera , Nicholas J. Beacher , Da-Ting Lin
{"title":"A device for simultaneous neural recording and drug infusion in rodents","authors":"Giovanni Barbera , Nicholas J. Beacher , Da-Ting Lin","doi":"10.1016/j.ohx.2025.e00721","DOIUrl":"10.1016/j.ohx.2025.e00721","url":null,"abstract":"<div><div>Here we present and validate an open-source motorized swivel which allows simultaneous neural and behavioral recording from rodents during drug infusion experiments. Cable and drug line tangling represents a limiting factor for neural recordings in freely moving rodents. This limits the scope of experiments that can be carried out using currently available commutators.</div><div>The proposed device offers a cost-effective solution to the problem of cable twisting and line tangling during experiments in freely moving rodents, enabling in vivo recordings for new experimental paradigms such as drug self-administration. Additionally, it requires minimal human supervision, simplifying the experimental design pipeline and facilitating scalability.</div><div>To demonstrate the usefulness and functionality of the device, we performed in vivo miniscope imaging in rat during a drug self-administration task, showing individual neurons’ response to drug seeking and consumption.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00721"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145519559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-09-23DOI: 10.1016/j.ohx.2025.e00708
Raffaella Salama , Miguel A. Rodríguez-Lázaro , Camil Castelo-Branco , Iñigo Herrero-Vidaurre , Laura Ribera-Torres , Emma Muñoz-Moreno , Jorge Otero , Ramon Farré
{"title":"Low-cost, open-source device for applying controlled olfactory stimuli during functional magnetic resonance imaging (fMRI) of the brain","authors":"Raffaella Salama , Miguel A. Rodríguez-Lázaro , Camil Castelo-Branco , Iñigo Herrero-Vidaurre , Laura Ribera-Torres , Emma Muñoz-Moreno , Jorge Otero , Ramon Farré","doi":"10.1016/j.ohx.2025.e00708","DOIUrl":"10.1016/j.ohx.2025.e00708","url":null,"abstract":"<div><div>Using functional magnetic resonance imaging (fMRI) to assess brain activity in response to olfactory stimuli is of great biomedical and clinical interest. However, application of controlled sequences of olfactory stimuli within the setting of fMRI equipment is challenging since the associated limitations for non-magnetic and non-conducive materials. Here, we have developed and tested a simple, low-cost, open-source, stand-alone device to apply selectable controlled sequences of olfactory stimuli in subjects undergoing fMRI. The device consists of an Arduino-controlled unit containing a blower-based airflow generator and a multichannel air valves system, a set of long air conducting tubing, and bubbler-based odor sources. The device was first validated on the bench to characterize the range of achievable flows, ensuring that the device can be adapted to a variety of applications and fMRI settings. The effectiveness of device performance was subsequently assessed in female patients with sexual dysfunction using a fMRI protocol based on subjecting them to controlled sequences of olfactive stimuli with pheromone, phenethyl alcohol (a rose fragrance) or neutral clean air. Therefore, the device facilitates biomedical research and clinical assessment of the neural pathways modulated by the olfactory system.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00708"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145320697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-10-08DOI: 10.1016/j.ohx.2025.e00714
Julius Bernd Zimmermann, Marcus Herbig
{"title":"OpenVac: An open-source low-cost fine vacuum sensor","authors":"Julius Bernd Zimmermann, Marcus Herbig","doi":"10.1016/j.ohx.2025.e00714","DOIUrl":"10.1016/j.ohx.2025.e00714","url":null,"abstract":"<div><div>When it comes to moisture- or air-sensitive chemicals, often the Schlenk technique is used to achieve safe and reliable results. In this article, we present an open-source and low-cost microcontroller-based alternative for vacuum sensors for this application. In Schlenk technique, the atmosphere in the reaction apparatus is replaced with an inert gas like argon or nitrogen. To do so, the apparatus first needs to be evacuated. To monitor the pressure level, vacuum sensors are used. Commercially available vacuum sensors typically are expensive and hard or even impossible to repair. Thus, we like to present our open-source and low-cost alternative, which uses a Pirani-type sensor and a Wheatstone bridge. The cross-voltage in this bridge circuit is amplified by an OpAmp and converted into a digital signal through a 12-bit ADC. The processing of this data is achieved through an ATtiny84, which also controls a 0.91-inch OLED display to show the current pressure. The device is battery powered and optimized for long runtime.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00714"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145320700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-09-28DOI: 10.1016/j.ohx.2025.e00711
Azlan Abdul Aziz , Nor Azriani Mohamad Nor , Wan Nurshazelin Wan Shahidan , Siti Nor Nadrah Muhamad , Nur Syuhada Muhammat Pazil , Syazwani Ya , Nur Faezah Omar
{"title":"MyNutriCapsule: An innovative approach to reduce water and nutrient waste in fertigation farming","authors":"Azlan Abdul Aziz , Nor Azriani Mohamad Nor , Wan Nurshazelin Wan Shahidan , Siti Nor Nadrah Muhamad , Nur Syuhada Muhammat Pazil , Syazwani Ya , Nur Faezah Omar","doi":"10.1016/j.ohx.2025.e00711","DOIUrl":"10.1016/j.ohx.2025.e00711","url":null,"abstract":"<div><div>Although fertigation offers substantial efficiency and productivity benefits, it also has significant drawbacks. Setting up a fertigation system requires considerable costs and knowledge and professionalism in managing soil, water, and fertiliser. Inefficient fertigation practices can also lead to groundwater contamination from nutrients leaching beyond the root zone. Consequently, this study aimed to introduce the MyNutriCapsule, an innovative product designed by Mr. Azlan Abdul Aziz, a senior lecturer from Universiti Teknologi MARA, Malaysia. The product was primarily employed to significantly reduce water and nutrient waste in fertigation agriculture. MyNutriCapsule recorded 98% and 18% reduction in fertiliser and liquid nutritional fertiliser wastage, respectively. The product also documented a 20% reduction in treated water consumption and a 27% decrement in overall operational costs. The observations validated the efficiency of MyNutriCapsule in promoting sustainable and cost-effective agricultural practices.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00711"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145362739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-09-02DOI: 10.1016/j.ohx.2025.e00694
Filip Wylęgała, Tadeusz Uhl
{"title":"Centrifugal device for dust adhesion measurement","authors":"Filip Wylęgała, Tadeusz Uhl","doi":"10.1016/j.ohx.2025.e00694","DOIUrl":"10.1016/j.ohx.2025.e00694","url":null,"abstract":"<div><div>This article details the design, construction, and operation of a benchtop centrifuge tailored for adhesion measurements. The device is intentionally simple, leveraging widely available components and exclusively employing 3D printing as the manufacturing method. The centrifuge facilitates the measurement of detachment forces, with user-adjustable sample attachment points via an interface or double-sided tape. The adhesion force is determined by considering both the detachment force and the mass of the dust; to achieve this, optical microscopy may be employed to determine the dust mass accurately. A user-friendly graphical interface allows for the input of desired rotational speeds and durations, while a built-in encoder and PID algorithm ensure precise operation.</div><div>Dust adhesion presents significant challenges for measurement, and this centrifuge addresses these challenges through a compact, modular design comprising four 3D-printed components, an Arduino Uno, a power socket, wiring, a motor controller, bearings, an encoder-equipped motor, and a plastic dome. Assembly is completed with a set of screws.</div><div>The primary application of this device is to evaluate the detachment forces of lunar regolith simulants on various materials. However, the design is versatile and can be adapted for spectrometry or as a compact centrifuge for biological applications.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00694"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-11-24DOI: 10.1016/j.ohx.2025.e00724
Prima Wijayakusuma , Galang Persada Nurani Hakim , Bin Li
{"title":"TerraGrow: Integrated platform for real time plant monitoring and automated watering system with IoT and fuzzy Sugeno Algorithm","authors":"Prima Wijayakusuma , Galang Persada Nurani Hakim , Bin Li","doi":"10.1016/j.ohx.2025.e00724","DOIUrl":"10.1016/j.ohx.2025.e00724","url":null,"abstract":"<div><div>Global water scarcity, climate variability, and rising input costs are pushing agriculture toward precise, evidence-based irrigation, yet many available systems remain proprietary, expensive, and difficult to adapt. TerraGrow is an open-source, low-cost controller that runs all sensing and closed-loop irrigation locally on a single ESP32, using real-time soil moisture, pH, temperature, and humidity inputs with a Sugeno-type fuzzy policy. Its modular and ergonomic hardware with a printable enclosure, integrated pump driver, and labeled connectors lets non-experts assemble, calibrate, and service the unit quickly in the field. Compared with earlier low-cost IoT irrigation nodes, TerraGrow’s novelty lies in fully local multi-sensor fuzzy control and an easy-to-deploy form factor supported by complete and reproducible design files. Bench and greenhouse tests showed stable moisture regulation and reduced unnecessary watering, enabled by precise sensing and a consistent hardware and firmware implementation. By combining local autonomy, simple deployment, and open documentation, TerraGrow makes practical precision irrigation more accessible to resource-constrained growers.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00724"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145614612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-08-29DOI: 10.1016/j.ohx.2025.e00697
Melissa Ruszczyk , Patrick M. Kiel , Santhan Chandragiri , Cedric M. Guigand , Johnnie Xia Zheng , Owen A. Brown , Brian K. Haus , Andrew C. Baker , Margaret W. Miller , Prannoy Suraneni , Chris Langdon , Vivek N. Prakash
{"title":"FlumeX: A modular flume design for laboratory-based marine fluid-substrate studies","authors":"Melissa Ruszczyk , Patrick M. Kiel , Santhan Chandragiri , Cedric M. Guigand , Johnnie Xia Zheng , Owen A. Brown , Brian K. Haus , Andrew C. Baker , Margaret W. Miller , Prannoy Suraneni , Chris Langdon , Vivek N. Prakash","doi":"10.1016/j.ohx.2025.e00697","DOIUrl":"10.1016/j.ohx.2025.e00697","url":null,"abstract":"<div><div>As research becomes more interdisciplinary, researchers develop new methodologies and technologies for novel experiments that bridge fields. FlumeX’s design features a standard experimental chamber that can be expanded into different configurations, allowing for cross-disciplinary experiments between the fields of fluid dynamics, chemical oceanography, and biology. An open-ended, flow-through configuration is ideal for simulating environments where water is constantly flushed, capable of simulating oceanic environments. A fully enclosed, recirculating configuration is ideal for particle image velocimetry experiments, standard for fluid dynamics. FlumeX is designed to allow for husbandry of sessile organisms, including corals, in tandem with chemical and physical measurements. FlumeX allows for flexibility in experimental design and comparable environments between recirculating and flow-through configurations. It is designed with low-cost, readily available materials, making it easy to build and produce en masse for replicate testing.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00697"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145099453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-11-04DOI: 10.1016/j.ohx.2025.e00719
David Sarabia-Jácome, Eduard Grasa, Marisa Catalán
{"title":"RINAsense: An open-source, low-power IoT sensor node for Recursive InterNetwork Architecture (RINA) Experimentation","authors":"David Sarabia-Jácome, Eduard Grasa, Marisa Catalán","doi":"10.1016/j.ohx.2025.e00719","DOIUrl":"10.1016/j.ohx.2025.e00719","url":null,"abstract":"<div><div>The proliferation of the Internet of Things (IoT) has exposed fundamental challenges in scalability, security, and management within conventional network architectures. The Recursive InterNetwork Architecture (RINA) presents a “clean slate” alternative, promising inherent solutions to these issues by redesigning networking from first principles. However, the practical exploration and adoption of RINA have been hampered by a lack of accessible, low-cost, and open-source hardware tailored for resource-constrained IoT environments. This paper introduces the RINAsense node, an open-source hardware platform designed to bridge this gap. The hardware is based on a low-power ESP32 microcontroller and integrates environmental sensors for temperature, humidity, and carbon monoxide, all managed by a custom RINAsense firmware designed specifically for embedded systems. The hardware was deployed and validated in an operational smart building testbed, demonstrating its capabilities as a reproducible scientific instrument. The validation confirmed the hardware’s successful operation, achieving low-latency communication with an average round-trip delay of 2.05 ms and a remarkable 82% reduction in energy consumption compared to non-optimized operation, a critical factor for battery-powered IoT devices. By providing a fully documented and replicable design, the RINAsense node lowers the barrier to entry for practical RINA research and experimentation, contributing directly to the open science and reproducibility goals of the research community.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00719"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145466667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-09-11DOI: 10.1016/j.ohx.2025.e00699
Otto Heuschele, R. Ted Jeo, D. Jo Heuschele
{"title":"A 3D printed grinder adaptor for streamlined sample processing","authors":"Otto Heuschele, R. Ted Jeo, D. Jo Heuschele","doi":"10.1016/j.ohx.2025.e00699","DOIUrl":"10.1016/j.ohx.2025.e00699","url":null,"abstract":"<div><div>In agricultural research, sample preparation for any type of post-harvest analysis is very time consuming. After harvesting samples, they generally need to be ground before further analysis. Grinding plant samples can be accomplished by either an abrasive type or blade type grinders. The abrasive type provides relatively uniform particle size; therefore, it is preferred to prepare material for analytical assays (1 mm). The Foss Cyclotec CT293 grinder comes with a glass container that needs to be removed and cleaned after each sample is ground. We developed a 3D printed adaptor cone that does not need to be removed after each sample and is cleaned when compressed air is vented through the machine to remove residual sample from the abrasive ring. This hardware reduces 27 % of time required for processing per sample (n = 60) and allows for direct sample grinding into different sample storage containers.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00699"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145050146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HardwareXPub Date : 2025-12-01Epub Date: 2025-09-19DOI: 10.1016/j.ohx.2025.e00703
Marcelo Barrientos , Martin Barrientos , Jorge Rodas , Alfredo Renault , Carlos Romero , Fabian Palacios , Claudio Chavez , Ana Martina Botti
{"title":"Temperature control board design and validation for skipper-CCD sensors using a buck converter","authors":"Marcelo Barrientos , Martin Barrientos , Jorge Rodas , Alfredo Renault , Carlos Romero , Fabian Palacios , Claudio Chavez , Ana Martina Botti","doi":"10.1016/j.ohx.2025.e00703","DOIUrl":"10.1016/j.ohx.2025.e00703","url":null,"abstract":"<div><div>This article describes the creation and validation of a custom temperature control board explicitly designed for Skipper-CCD sensors. The board is versatile and can be used in various experimental setups. It consists of two galvanically isolated sections: a control section equipped with a Raspberry Pi and essential instrumentation for measurement and protection, and a power section with a buck converter and additional instrumentation for enhanced protection and monitoring. The seamless integration of these sections provides robust temperature control and comprehensive safeguards against potential issues. Through careful design and extensive experimental validation, the developed board ensures precise thermal management tailored to the unique needs of Skipper-CCD sensors. Its effectiveness has been demonstrated in the OSCURA experiment and can serve as a model for potential applications in other projects.</div></div>","PeriodicalId":37503,"journal":{"name":"HardwareX","volume":"24 ","pages":"Article e00703"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145118886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}