控制体外膜氧合的开放式智能血泵平台

IF 2 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC
Gabriella Glomp , Michael Cortelli , Briana Bernicker , Matthew Bacchetta , Rei Ukita
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引用次数: 0

摘要

用于体外膜氧合(ECMO)的临床血泵控制台由于其高成本,研究人员很难获得。此外,临床机器是在高水平的信息安全下建造和设计的,这限制了它们与第三方机器和软件的集成。这些障碍阻碍了研究人员根据他们的研究需求定制血泵控制台,限制了血泵自动化和脉动领域的创新和进步。为了满足这些需求,我们提出了一个可编程的智能血泵控制台。这款控制台的组装成本不到200美元,使用包括Arduino在内的开源工具。使用该控制台,离心血泵头可以在体外生命支持应用所需的临床相关流量和压力水平下操作(250毫米汞柱压力头,4升/分钟血流量)。此外,可编程的特性允许超出临床体外血泵的标准适应症的效用,包括脉搏和伺服控制。对于未来的方向,这个控制台将进一步发展,以适应更广泛的临床泵头。我们设想这将是一个经济实惠的开放访问平台,以满足工程师和研究人员在促进ECMO技术创新方面的不同需求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Open-access smart blood pump platform for controlling extracorporeal membrane oxygenation

Open-access smart blood pump platform for controlling extracorporeal membrane oxygenation
Clinical blood pump consoles for extracorporeal membrane oxygenation (ECMO) are poorly accessible to researchers due to their high cost. Furthermore, clinical machines are built and designed at a high level of information security, which limits their integration with third-party machines and software. These barriers hinder researchers from customizing blood pump consoles for their investigational needs, limiting innovations and advancements in the areas of blood pump automation and pulsation. To address these needs, we present on a programmable Smart Blood Pump console. This console can be assembled for under $200 and uses open-source tools including Arduino. Using this console, centrifugal blood pump heads can be operated at clinically relevant levels of flow and pressure needed in extracorporeal life support applications (>250 mmHg pressure head, >4 L/min of blood flow). Additionally, the programmable nature allows for utility beyond the standard indications of clinical extracorporeal blood pumps, including pulsatility and servo control. For future directions, this console will be further developed to accommodate a wider range of clinical pump heads. We envision that this will be an affordable, open-access platform to suit the varying needs of engineers and researchers for fostering innovations in ECMO technology.
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来源期刊
HardwareX
HardwareX Engineering-Industrial and Manufacturing Engineering
CiteScore
4.10
自引率
18.20%
发文量
124
审稿时长
24 weeks
期刊介绍: HardwareX is an open access journal established to promote free and open source designing, building and customizing of scientific infrastructure (hardware). HardwareX aims to recognize researchers for the time and effort in developing scientific infrastructure while providing end-users with sufficient information to replicate and validate the advances presented. HardwareX is open to input from all scientific, technological and medical disciplines. Scientific infrastructure will be interpreted in the broadest sense. Including hardware modifications to existing infrastructure, sensors and tools that perform measurements and other functions outside of the traditional lab setting (such as wearables, air/water quality sensors, and low cost alternatives to existing tools), and the creation of wholly new tools for either standard or novel laboratory tasks. Authors are encouraged to submit hardware developments that address all aspects of science, not only the final measurement, for example, enhancements in sample preparation and handling, user safety, and quality control. The use of distributed digital manufacturing strategies (e.g. 3-D printing) is encouraged. All designs must be submitted under an open hardware license.
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