Journal of Contemporary Dental Practice最新文献

{"title":"Assessment of Treatment Outcomes with Complete Orthograde Obturation with Bioceramic Materials: A Scoping Review.","authors":"Murali H Rao, Rajkumar Krishnan, Mamatha Kumaraswamy, Aditya Keshav, Pavithra Gopal, Elizabeth Thomas","doi":"10.5005/jp-journals-10024-3764","DOIUrl":"10.5005/jp-journals-10024-3764","url":null,"abstract":"<p><strong>Aim: </strong>Bioceramic sealers are being used as obturation materials as they are known for hard tissue induction and facilitating periapical healing. Based on some <i>in vitro</i> studies, one can hypothesize that mineral trioxide aggregate (MTA) and biodentine used as the sole obturating material could reinforce the tooth and provide a better sealability than an MTA/biodentine apical plug with gutta-percha obturation. However, there are not many high-quality studies regarding outcomes of complete MTA/biodentine obturations compared with traditional obturation methods. The aim of this review is to organize findings of clinical outcomes and the quality of complete obturation of root canals from various <i>in vitro</i> studies and to identify the gaps in research done in this area.</p><p><strong>Methods: </strong>The preferred reporting items for Systematic Reviews and Meta-analyses Extension for Scoping Reviews guidelines were followed to conduct a thorough literature search in June 2024 across PubMed, Google Scholar, Scopus, Science Direct, and Scielo. The research question was formulated using PICO: population: permanent dentition in adults or children; intervention: orthograde monoblock obturation; comparator: traditional orthograde root canal filling methods; outcome: success defined by asymptomatic, functional tooth, and radiographic evidence of healing.</p><p><strong>Results: </strong>Out of 511 initially identified studies, 474 studies did not meet initial eligibility criteria for inclusion, and only 37 studies were selected. After full-text scrutiny, only 23 were subjected to qualitative assessment.</p><p><strong>Conclusion: </strong>The findings of the data concluded that complete obturation with MTA and biodentine could be a viable alternative to an apical plug followed by gutta-percha obturation or bioceramic sealer with gutta-percha obturation. The lack of randomized controlled trials and long-term retrospective studies precludes clinicians from utilizing this technique.</p><p><strong>Clinical significance: </strong>Bioceramic materials can be used for complete obturation of canals, both in primary and retreatment cases, bringing about periapical healing and regeneration of tissues. They are found to reinforce and improve the strength of radicular structure on account of the monoblock effect. How to cite this article: Rao MH, Krishnan R, Kumaraswamy M, <i>et al</i>. Assessment of Treatment Outcomes with Complete Orthograde Obturation with Bioceramic Materials: A Scoping Review. J Contemp Dent Pract 2024;25(12):1190-1197.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 12","pages":"1190-1197"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Vitamin D3 on Postorthodontic Treatment Stability: A Randomized Controlled Trial.","authors":"Thrivikhraman Kothandaraman, Prema Anbarasu, Sp Saravana Dinesh, Saravana Kumar Subramanian, Gabriel Eisenhuth, Sebastian Eisenhuth, Claudia Eisenhuth","doi":"10.5005/jp-journals-10024-3795","DOIUrl":"10.5005/jp-journals-10024-3795","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to clinically evaluate whether the local administration of vitamin D3 enhances postorthodontic tooth stability over a period of 3 months immediately after debonding.</p><p><strong>Materials and methods: </strong>Patients aged 15-30 years with dental malocclusion and moderate crowding in the lower arch (Little's irregularity score of 4-6) were selected and randomly split into the experimental and the control groups. After complete alignment and leveling, vitamin D3 injection was delivered to the experimental group and the control group was given a placebo injection with 0.9% normal saline mixed with 2% lignocaine. Fourteen days after the injection, the lower archwires were removed from the control and experimental groups.</p><p><strong>Results: </strong>Relapse was significantly higher in control than in the experimental group at all-time intervals. Statistically significant values of relapse were observed at T2 and T3 intervals between the two groups, with greater relapse in the control group than in the experimental group. Inter-canine width, arch perimeter, and intermolar width showed mild changes over 3-month period, but there were no significant differences between the two groups.</p><p><strong>Conclusion: </strong>Relapse was seen in both the control and the experimental in the first 4 weeks of the study. Still, the control group showed a greater relapse rate in the following 8th week and 12th week when compared to the experimental group. How to cite this article: Kothandaraman T, Anbarasu P, Dinesh SPS, <i>et al</i>. Impact of Vitamin D3 on Postorthodontic Treatment Stability: A Randomized Controlled Trial. J Contemp Dent Pract 2024;25(12):1156-1161.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 12","pages":"1156-1161"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Obstructive Sleep Apnea on Masticatory Muscle Function.","authors":"Diana Russo, Luis Eduardo Almeida, Vincenzo Ronsivalle, Marco Cicciù, Gabriele Cervino, Maria Maddalena Marrapodi, Giuseppe Minervini","doi":"10.5005/jp-journals-10024-3783","DOIUrl":"10.5005/jp-journals-10024-3783","url":null,"abstract":"<p><p>How to cite this article: Russo D, Almeida LE, Ronsivalle V, <i>et al.</i> Impact of Obstructive Sleep Apnea on Masticatory Muscle Function. J Contemp Dent Pract 2024;25(11):997-1000. Keywords: Apnea-hypopnea index, Diabetes, Obstructive sleep apnea, Temporomandibular joint.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"997-1000"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Evaluation of Osseodensification vs Conventional Osteotomy Technique on Primary and Secondary Implant Stability in Rabbit Model Split Body RCT.","authors":"Sudhakar Arpudaswamy, S Syed A Ali, Suma Karthigeyan, Ponnanna A Appanna, K Vinod Kumar, Rohit M Shetty","doi":"10.5005/jp-journals-10024-3751","DOIUrl":"10.5005/jp-journals-10024-3751","url":null,"abstract":"<p><strong>Aim and objective: </strong>To measure and contrast primary stability metrics, such as insertion torque values and implant stability quotient (IQS) at the time of implant placement, and secondary stability metrics, such as ISQ three months post-implant insertion, between implants inserted in osteotomy sites prepared with conventional drills and osseodensification drills (OD) in the femoral condyles of female New Zealand white rabbits, which are characterized by low-density D4 type bone.</p><p><strong>Materials and methods: </strong>Eight female New Zealand white strain rabbits, each 14 weeks old and weighing approximately 2.5 ± 0.3 kg, were utilized for this study. Using aseptic techniques and local anesthesia, a 3.1 × 8 mm implant was inserted into the rabbit's left femoral condyle using conventional drills (group I) from the Zimmer surgical kit. Similarly, using Densah drills (group II), a 3.1 mm × 8 mm implant was inserted into the rabbit's right femoral condyle. Primary implant stability was evaluated using insertional torque and ISQ values during insertion of implants using a torque wrench and radiofrequency analyzer, respectively. Secondary implant stability was evaluated by measuring ISQ values three months after implant placement.</p><p><strong>Results: </strong>Group I had a mean insertional torque of 31.13 ± 1.727 Ncm, while group II had 33.00 ± 1.309 Ncm. ISQ during insertion was 63.63 ± 5.927 in group I and 63.62 ± 7.615 in group II. After three months, ISQ was 67.25 ± 6.45 in group II and 75 ± 6.85 in group II. Significant differences were found in insertional torque (<i>p</i> = 0.028), ISQ after three months (<i>p</i> = 0.0353), and ISQ changes over time (<i>p</i> = 0.001), but not in ISQ at the time of implant placement.</p><p><strong>Conclusion: </strong>The investigation demonstrated that implants placed using the OD exhibited superior initial stability and subsequent stability progression compared to those placed using conventional drilling techniques in a rabbit model.</p><p><strong>Clinical significance: </strong>Primary and secondary implant stability are critical factors for successful implant treatment in clinical practice. Osseodensification demonstrates a higher insertional torque and implant stability quotient by enhancing bone density and volume surrounding implants. This enhanced stability can lead to improved osseointegration and reduced healing times, ultimately benefiting patients with compromised bone quality. How to cite this article: Arpudaswamy S, Ali SSA, Karthigeyan S, <i>et al.</i> Comparative Evaluation of Osseodensification vs Conventional Osteotomy Technique on Primary and Secondary Implant Stability in Rabbit Model Split Body RCT. J Contemp Dent Pract 2024;25(11):1052-1059.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"1052-1059"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physicochemical Properties and Bacterial Adhesion of Conventional and 3D Printed Complete Denture PMMA Materials: An <i>In Vitro</i> Study - Part I.","authors":"Pierre Khoury, Naji Kharouf, Olivier Etienne, Jean-Philippe Dillenseger, Youssef Haikel, Hatem M El-Damanhoury, Dani Irani, Mutlu Ozcan, Ziad Salameh","doi":"10.5005/jp-journals-10024-3781","DOIUrl":"10.5005/jp-journals-10024-3781","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate and compare the surface morphology, wettability, roughness, and bacterial adhesion properties of polymethyl methacrylate (PMMA) materials fabricated by conventional methods and 3D printing for complete denture applications.</p><p><strong>Materials and methods: </strong>Two PMMA materials were investigated: Conventionally processed (ProBase Hot) and 3D-printed (3DP) (V-Print Dentbase). Surface morphology (<i>n</i> = 3) was analyzed using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). Surface roughness (<i>n</i> = 10) was measured using an optical profilometer. Wettability was assessed through contact angle measurements (<i>n</i> = 6) at 10, 30, and 60 seconds. Bacterial adhesion (<i>n</i> = 9) and biofilm formation (<i>n</i> = 3) were evaluated using <i>Escherichia coli</i> (<i>E. coli</i>) as a model organism, with quantitative bacterial counts and SEM analysis of bacterial morphology. Data were statistically analyzed.</p><p><strong>Results: </strong>Scanning electron microscopy analysis revealed nanoparticles on the surface of 3DP samples, while EDX detected silicon in these samples, absent in conventional PMMA. 3D-printed surfaces exhibited significantly lower roughness (1.05 ± 0.32 µm) compared to conventional surfaces (20.46 ± 6.71 µm) (<i>p</i> < 0.001). Contact angle measurements showed that 3DP surfaces were more hydrophilic (64-68°) than conventional surfaces (100°) (<i>p</i> < 0.05). Bacterial adhesion studies demonstrated more adherent bacteria on 3DP surfaces (92.5 ± 30.8) compared to the conventional surfaces (57.6 ± 12.5), but biofilm formation was observed only on conventional surfaces.</p><p><strong>Conclusion: </strong>3D-printed PMMA exhibited distinct surface characteristics compared to conventionally processed PMMA, including the presence of silicon nanoparticles, lower surface roughness, and higher hydrophilicity. While 3DP surfaces showed higher initial bacterial adherence, in contrast, they appeared to inhibit biofilm formation, which highlights the complex nature of bacterial interactions with these materials.</p><p><strong>Clinical significance: </strong>Further clinical studies are needed to validate the results of this investigation and generate clinical translational data. How to cite this article: Khoury P, Kharouf N, Etienne O, <i>et al.</i> Physicochemical Properties and Bacterial Adhesion of Conventional and 3D Printed Complete Denture PMMA Materials: An <i>In Vitro</i> Study - Part I. J Contemp Dent Pract 2024;25(11):1001-1008.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"1001-1008"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>In Vitro</i> Comparison of Color Matching: Universal Shade Composite Resin vs Multi-shade Conventional Composite.","authors":"Walaa F Bisharah, Ahmed S Zahran, Mona T Rajeh, Nada A AbdelAleem","doi":"10.5005/jp-journals-10024-3780","DOIUrl":"10.5005/jp-journals-10024-3780","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to evaluate and compare the color matching of OMNICHROMA (OM), a universal shade composite, to the well-established 3M Filtek Z350 composites (FT).</p><p><strong>Materials and methods: </strong>An <i>in vitro</i> experimental study was conducted on 80 freshly extracted permanent teeth, with intact buccal surfaces. The teeth were randomly assigned to four groups: Group I OM and groups II, III, and IV (3M Filtek Z350 in shades A3, A3.5, and B2, respectively). Class V cavity preparations were created and restored using the respective composites. Color matching was assessed instrumentally using a spectrophotometer to calculate the color difference (Δ<i>E</i>) values and visually by three trained observers using a standardized visual scoring system.</p><p><strong>Results: </strong>Visual assessments showed no significant differences in color matching across the four groups. However, the Δ<i>E</i> color matching analysis revealed significant differences (<i>p</i> < 0.0001), with OM exhibiting higher Δ<i>E</i> values compared to FT shades A3.5 and B2. No significant difference was found between OM and shade A3.</p><p><strong>Conclusion: </strong>OMNICHROMA demonstrated excellent visual color matching, comparable to the various shades of FT composites. Despite the higher Δ<i>E</i> values observed instrumentally in comparison to shades A3.5 and B2, OM's ability to blend with different tooth shades visually was highly effective.</p><p><strong>Clinical significance: </strong>These results suggest that OM offers a versatile and reliable option for achieving satisfactory esthetic outcomes, reducing the need for multiple shade variations in restorative procedures. How to cite this article: Bisharah WF, Zahran AS, Rajeh MT, <i>et al.</i> <i>In Vitro</i> Comparison of Color Matching: Universal Shade Composite Resin vs Multi-shade Conventional Composite. J Contemp Dent Pract 2024;25(11):1039-1044.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"1039-1044"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Effectiveness of Nanocrystalline Hydroxyapatite and Demineralized Bone Matrix Combined with Titanium-platelet Rich Fibrin for Ridge Preservation: A Randomized Controlled Clinical Trial.","authors":"Ruchita T Patil, Prasad V Dhadse, Shrishti S Salian, Sanehi D Punse, Pavan Bajaj, Ranu Oza","doi":"10.5005/jp-journals-10024-3786","DOIUrl":"10.5005/jp-journals-10024-3786","url":null,"abstract":"<p><strong>Aim: </strong>Preservation of ridge dimensions is the important aspect after tooth extraction for prosthetic and implant rehabilitation. Titanium-platelet rich fibrin (T-PRF) is an autologous biomaterial, and when used with bone graft it could enhance the bone regeneration. Hence, the aim of this study was to evaluate the combined effect of T-PRF with nanocrystalline hydroxyapatite (Nano-HA) and T-PRF with demineralized bone matrix (DMBM).</p><p><strong>Materials and methods: </strong>Twenty systemically healthy patients were included in the study and were randomly assigned into two groups. Ten patients were treated with atraumatic extraction followed by ridge preservation using Nano-HA bone graft and T-PRF. In another group of ten patients, ridge preservation was done using a xenograft-DMBM. Preoperative cone beam computed tomography (CBCT) and postoperative CBCT after 3 months were evaluated for bone fill. The clinical parameters of ridge width (RW) and ridge height were measured clinically, with the help of UNC 15 probe, after 3 months.</p><p><strong>Results: </strong>The treatment modality resulted in significant bone fill in CBCT and adequate RW clinically in both the groups. The mean bone density in the Nano-HA + T-PRF group was recorded as 776.72 ± 223.94, and 854.72 ± 183.57 was observed in the DMBM + T-PRF group, after 14-16 weeks.</p><p><strong>Conclusion: </strong>The study's findings indicate that ridge preservation performed at the time of extraction is a reliable and predictable approach for minimizing alveolar bone resorption. Additionally, the combination of T-PRF with bone grafts yields effective results in a relatively short timeframe.</p><p><strong>Clinical significance: </strong>This technique involves combining osteoconductive material from Nano-HA and DMBM and the growth factor-rich matrix of T PRF for quicker healing and better esthetic and functional results. It reduces morbidity in patients, does not require an autogenous graft, is biocompatible, and is economical; therefore, both clinical practice and regenerative research in the field of dentistry are advanced. Hence, it is one of the important evidences through this original study. How to cite this article: Patil RT, Dhadse PV, Salian SS, <i>et al.</i> Evaluation of Effectiveness of Nanocrystalline Hydroxyapatite and Demineralized Bone Matrix Combined with Titanium-platelet Rich Fibrin for Ridge Preservation: A Randomized Controlled Clinical Trial. J Contemp Dent Pract 2024;25(11):1069-1076.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"1069-1076"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fracture Resistance of Anterior Teeth Restored with Post-retained Ceramic Crown vs Ceramic Endocrowns.","authors":"Abdelrahman A Mohamed, Mohamed Ba Badawy, Ahmed My El-Kouedi, Ahmed Ml Alameldin","doi":"10.5005/jp-journals-10024-3785","DOIUrl":"10.5005/jp-journals-10024-3785","url":null,"abstract":"<p><strong>Aim: </strong>To compare the fracture resistance of anterior teeth restored with either glass fiber post (GFP) and conventional lithium disilicate (LDS) crowns or endocrowns made of LDS or hybrid ceramics.</p><p><strong>Materials and methods: </strong>A total of 21 central incisors with 2-mm ferrule and 1-mm shoulder finish line were applied in this investigation. The teeth were divided into three main groups (<i>n</i> = 7) according to the type of restoration used: PC glass fiber post (GFP) and e-max crown, EE (LDS endocrown), and VE (Vita-Enamic endocrown). Mechanical cyclic loading was conducted in a chewing simulator to simulate 6 months of clinical use. Fracture resistance and failure mode were assessed; further examination of fractured specimens was done with scanning electron microscopy.</p><p><strong>Results: </strong><i>Post-hoc</i> Tukey's test was performed to investigate the pairwise differences in fracture resistance among the three groups, and the results were <i>p</i> = 0.0452 between PC and VE groups, which is significant statistically. In contrast, <i>p</i> = 0.0615 between PC and EE groups, which is not significantly different. Chi-square test was made to analyze the results of mode of failure among the three groups, and there was a significant difference; <i>p</i>-value = 0.0289.</p><p><strong>Conclusion: </strong>The LDS endocrowns show fracture resistance similar to that of GFP-supported full coverage LDS crowns, with advantage of more restorable mode of fractures. Vita-Enamic endocrowns, despite having fracture resistance lower than other groups, showed fracture resistance higher than the physiologic load, with restorable fractures more than both LDS endocrowns and GFP LDS crowns.</p><p><strong>Clinical significance: </strong>For dental practitioners, endocrowns in damaged anterior endodontically treated teeth provide similar fracture resistance to GFP and full crowns, with the advantage of more restorable fractures if occurred. How to cite this article: Mohamed AA, Badawy MBA, El-Kouedi AMY, <i>et al.</i> Fracture Resistance of Anterior Teeth Restored with Post-retained Ceramic Crown vs Ceramic Endocrowns. J Contemp Dent Pract 2024;25(11):1045-1051.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"1045-1051"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Serum Calcium and Vitamin D Levels in Patients with and without Periodontitis before and after Nonsurgical Periodontal Therapy.","authors":"Srishti Wadhwa, Kumar Saurav, Sachit A Arora, Rupali Kalsi, Gunjan Gupta, Shivesh Mishra, Ritika Gupta","doi":"10.5005/jp-journals-10024-3775","DOIUrl":"10.5005/jp-journals-10024-3775","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate and correlate levels of serum calcium and 25-hydroxycholecalciferol (vitamin D) in subjects with periodontitis and in subjects with healthy periodontium before and following nonsurgical periodontal therapy (NSPT).</p><p><strong>Materials and methods: </strong>A total of 52 patients were enrolled in the study with 26 patients in each group. The control group included patients without periodontitis, whereas the study group included patients with periodontitis. On the first visit, ~ 3-5 mL of venous blood was collected from all the participants for the assessment of calcium and Vitamin D levels in the blood. The various parameters evaluated included probing depth, clinical attachment level (CAL), gingival index (Loe and Silness 1963). Plaque index (Silness and Loe 1964), and IOPA (site having greatest pocket depth). Participants of both the groups received NSPT which involved extensive scaling and root planing. On the second visit (after 3 months), the same clinical parameters except IOPA were recorded in all the participants. On the third visit (after 6 months from the first visit), the blood sample was again collected for the evaluation of serum calcium and Vitamin D, and all the parameters of baseline were recorded.</p><p><strong>Result: </strong>The result of the study showed that Vitamin D levels at baseline were less in test subjects (12.73 ± 2.25) as compared to controls (17.81 ± 4.03), which improved at 6 months for the test group (24.53 ± 1.98) but not the control group (17.8 ± 4.14) following NSPT. All the clinical parameters improved for both groups. There was no statistically significant difference in the calcium levels of both groups at baseline or 6 months.</p><p><strong>Conclusion: </strong>Vitamin D levels were found to be lower in periodontitis patients than healthy controls, vitamin D levels improved in the test subjects along with the clinical parameters following NSPT highlighting the beneficial role of Vitamin D in maintaining periodontal health. No changes were seen in calcium levels in either of the groups at any point in time.</p><p><strong>Clinical significance: </strong>Vitamin D can reduce the incidence and severity of periodontal disease by its various anti-inflammatory and immunomodulatory effects in addition to its traditional role in bone metabolism. Thus, maintaining adequate levels of systemic vitamin D could be critical to periodontal health. This study justifies this notion and further suggests the adjunctive role of vitamin D supplementation to improve therapeutic outcomes. How to cite this article: Wadhwa S, Saurav K, Arora SA, <i>et al.</i> Correlation of Serum Calcium and Vitamin D Levels in Patients with and without Periodontitis before and after Nonsurgical Periodontal Therapy. J Contemp Dent Pract 2024;25(11):1034-1038.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"1034-1038"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Glucose-6-Phosphate dehydrogenase in Saliva of Subjects with Normal Appearing Gingiva and Periodontitis using qRT-PCR: A Cross-sectional Study.","authors":"Ninad V Chavan, Sahana Srinath, Satish Thimmaiah Yadava, Savita Shiragur, Akalya Purushothaman, Hajira Khatoon, Vaishnavi Setloor","doi":"10.5005/jp-journals-10024-3772","DOIUrl":"10.5005/jp-journals-10024-3772","url":null,"abstract":"<p><strong>Aims: </strong>To determine the salivary level of glucose-6-phosphate dehydrogenase (G6PD) in subjects with normal appearing gingiva and periodontitis, and to compare the salivary levels of G6PD in all the study groups.</p><p><strong>Materials and methods: </strong>Unstimulated saliva (4 mL) was collected from 30 subjects; 15 periodontitis subjects and 15 control subjects. Later, saliva samples were subjected to RNA extraction via TRIzol method. The RNA was converted to complementary DNA, and quantitative real time polymerase chain reaction was set-up.</p><p><strong>Results: </strong>The expression of salivary G6PD in periodontitis subjects showed a significant increase when compared with control subjects, with a <i>p</i>-value of 0.001 (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>In conclusion, the overall results show promise in future aspects of G6PD as a potential diagnostic as well as a prognostic marker. However, large-scale, multi-institutional, and large sample sized studies should be conducted to further find out the importance of G6PD in the diagnosis of periodontitis and its prognostic value.</p><p><strong>Clinical significance: </strong>The increase of G6PD levels in periodontitis subjects shows the increased oxidative stress, and this can be used for developing new noninvasive diagnostic procedures, developing novel treatment modalities, and also in assessing prognosis of treated cases of periodontitis. How to cite this article: Chavan NV, Srinath S, Yadava ST, <i>et al.</i> Evaluation of Glucose-6-Phosphate dehydrogenase in Saliva of Subjects with Normal Appearing Gingiva and Periodontitis using qRT-PCR: A Cross-sectional Study. J Contemp Dent Pract 2024;25(11):1060-1068.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"1060-1068"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}