Journal of Contemporary Dental Practice最新文献

{"title":"Integrated Computational and Cross-sectional Analysis of Thrombotic Non-coding RNAs as Salivary and Plasma Biomarkers in Coronary Artery Disease.","authors":"Arthisri A Sekar, Vishnu P Veeraraghavan, A Thirumal Raj, Shankargouda Patil","doi":"10.5005/jp-journals-10024-4042","DOIUrl":"10.5005/jp-journals-10024-4042","url":null,"abstract":"<p><strong>Aim and background: </strong>Epicardial adipose tissue (EAT), adjacent to the myocardium, plays a role in coronary artery disease (CAD), though its thrombotic mechanisms remain unclear. This study aimed to identify CAD-specific thrombotic messenger RNAs (mRNAs) and their regulatory microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) using expression analysis, network modeling, and clustering approaches.</p><p><strong>Materials and methods: </strong>Differential gene expression analysis was performed using the GSE64554 dataset (<i>p</i> < 0.05), identifying genes dysregulated in CAD. Thrombosis-related genes were retrieved from GeneCards and intersected with CAD-associated genes. Protein-protein interaction (PPI) networks were constructed to determine key hub genes. MicroRNAs and long noncoding RNA analyses were conducted to identify regulatory modules. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was used to validate key miRNA expression in plasma and saliva samples from CAD patients (<i>n</i> = 30) and healthy controls (<i>n</i> = 30).</p><p><strong>Results: </strong>A total of 840 genes were upregulated in CAD, with 85 overlapping thrombosis-related genes identified. Network analysis highlighted five key thrombosis-CAD hub genes involved in immune response, cytokine signaling, and signal transduction. miRNA profiling revealed 82 downregulated miRNAs in CAD, many targeting these hub genes. Of 1,122 regulatory modules analyzed, <i>HIF1A,</i> <i>CTNNB1,</i> and <i>CCL5</i> were identified as central regulators. Integration of lncRNA data further emphasized hsa-miR-641 as a key regulatory miRNA, significantly downregulated in both plasma and saliva samples from CAD patients, as confirmed by RT-qPCR.</p><p><strong>Conclusion: </strong>This study identifies key thrombotic genes and regulatory modules in EAT, emphasizing the role of immune and signaling pathways in CAD progression. The consistent downregulation of hsa-miR-641 and its detectability in plasma and saliva support its potential as a reliable noninvasive diagnostic biomarker.</p><p><strong>Clinical significance: </strong>hsa-miR-641 can serve as a non-invasive biomarker for early detection of CAD using saliva and plasma. It may also aid in risk assessment and guide targeted therapeutic strategies.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 3","pages":"294-303"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148228478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphometric Evaluation of Cervical Vertebral Age and Mandibular Growth in Skeletal Class II Individuals Using Digital Cephalometry: A Cross-sectional Study.","authors":"Yousef M Almugla","doi":"10.5005/jp-journals-10024-4008","DOIUrl":"https://doi.org/10.5005/jp-journals-10024-4008","url":null,"abstract":"<p><strong>Aims: </strong>This study examined the association between morphometric cervical vertebral bone (CVB) age and mandibular growth in Saudi individuals with skeletal class II malocclusion.</p><p><strong>Materials and methods: </strong>A retrospective cross-sectional analysis was performed using archived digital lateral cephalograms of 56 Saudi patients with skeletal class II malocclusion. Radiographs were categorized into a pubertal group (8-13 years; <i>n</i> = 28) and a postpubertal group (17-21 years; <i>n</i> = 28), with each group equally stratified by gender (14 males and 14 females). Mandibular length estimates calculated during the pubertal phase were compared with measured mandibular dimensions in postpubertal subjects, and sex-related growth differences were evaluated. Cervical vertebral bone age was calculated using vertebral morphometric measurements, and mandibular length (Condylion-Gnathion) was digitally assessed. Predicted mandibular lengths derived from CVB age were statistically compared with observed postpubertal values using independent <i>t</i>-tests, Cohen's <i>d,</i> and descriptive Bland-Altman analysis.</p><p><strong>Results: </strong>Chronological age (CA) demonstrated no significant discrepancy from CVB age in either males (<i>p</i> = 0.28) or females (<i>p</i> = 0.63). Mandibular lengths predicted during the pubertal phase did not differ significantly from observed mandibular dimensions in the postpubertal group, for both sexes (<i>p</i> > 0.05). Bland-Altman analysis demonstrated minimal bias and acceptable group-level agreement, with higher precision in females. Males exhibited greater but more variable estimated growth potential than females.</p><p><strong>Conclusion: </strong>Morphometric CVB age showed good group-level agreement between mandibular length predicted during the pubertal phase (8-13 years) and measured postpubertal values (17-21 years) in Saudi skeletal class II subjects.</p><p><strong>Clinical significance: </strong>Accurate assessment of mandibular growth timing remains essential for optimizing orthopedic intervention in skeletal class II malocclusion. This study highlights the clinical applicability of CVB morphometric assessment as a practical, radiation-free approach using routine cephalograms to estimate mandibular growth potential and support informed treatment timing decisions.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 3","pages":"231-236"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148228535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of a Novel Zygomatic-based Cephalometric Angle for Sagittal Skeletal Discrepancy: A Retrospective Study.","authors":"Subramanya Shetty, Dilshad Umar, Kelly Ctm Egipsy, Mohammed Khais","doi":"10.5005/jp-journals-10024-4036","DOIUrl":"10.5005/jp-journals-10024-4036","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the diagnostic accuracy of a novel zygomatic-based cephalometric parameter, the ZYen angle, for assessing sagittal skeletal discrepancies.</p><p><strong>Materials and methods: </strong>This retrospective cross-sectional study analyzed 369 pretreatment lateral cephalograms of subjects aged 18-25 years, equally distributed into skeletal class I (<i>n =</i> 123), class II (<i>n =</i> 123), and class III (<i>n =</i> 123) groups. Skeletal classification was performed using the A point-nasion-B point angle (ANB) and Wits appraisal. The ZYen angle, defined using points M, Z (zygomatic point), and D, was measured, and its diagnostic performance was assessed using one-way analysis of variance (ANOVA) and receiver operating characteristic (ROC) curve analysis to determine sensitivity, specificity, and area under the curve (AUC).</p><p><strong>Results: </strong>The ZYen angle showed significant differences among skeletal classes (<i>p <</i> 0.001). Receiver operating characteristic analysis demonstrated excellent discrimination between skeletal class I and class III (AUC = 0.908), with a cut-off value of 29.5° providing balanced sensitivity (78.9%) and specificity (82.9%). In contrast, discrimination between class I and class II was poor (AUC = 0.594), indicating limited diagnostic ability for identifying class II patterns.</p><p><strong>Conclusion: </strong>The ZYen angle is a reliable sagittal skeletal parameter with high diagnostic accuracy for distinguishing class I from class III relationships but limited utility in differentiating class II malocclusions.</p><p><strong>Clinical significance: </strong>Accurate sagittal skeletal diagnosis is essential for orthodontic treatment planning and prognosis. The ZYen angle utilizes stable zygomatic landmarks and minimizes reliance on cranial base and dental reference points, enhancing diagnostic confidence in class III cases. It may serve as a clinically useful adjunct to conventional cephalometric parameters, particularly in borderline or ambiguous sagittal discrepancies.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 3","pages":"304-309"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148228547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Radiological Characteristics of Styloid Process Calcifications in Panoramic Radiographs of Dominican Individuals: A Cross-sectional Study.","authors":"Mario A Abréu-Cruz, Vanessa Madera-Reynoso, Jhoana M Llaguno-Rubio, Gustavo A Fiori-Chincaro, Luis E Arriola-Guillén","doi":"10.5005/jp-journals-10024-4030","DOIUrl":"10.5005/jp-journals-10024-4030","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to determine the prevalence and radiological characteristics of styloid process calcifications in panoramic radiographs of Dominican individuals from 2021 to 2025.</p><p><strong>Materials and methods: </strong>We conducted a retrospective cross-sectional study using 7,915 panoramic radiographs of adults. Mineralization of the styloid process was assessed using the O'Carroll method, and the morphology was classified according to the Langlais classification. Two trained and calibrated radiologists made all measurements. Inter- and intraobserver agreement was evaluated using the κ index. Statistical analysis included Fisher's exact test and binomial logistic regression, with a significance level set at <i>p</i> < 0.05.</p><p><strong>Results: </strong>A total of 25% (<i>n</i> = 1,984) of the population exhibited calcifications, with no significant association with sex. Bilateral calcifications were more prevalent, occurring in 74.9% (<i>n</i> = 1,483) of the cases. Partial calcification was more common in women, whereas elongated and segmented patterns showed significant differences between the sexes. Additionally, age was found to increase the risk of calcification; specifically, for each additional year of age, the risk of calcification increases by a factor of 1.017 [confidence interval (CI): 1.014-1.021].</p><p><strong>Conclusion: </strong>Calcifications of the styloid processes are common among the Dominican population. Careful radiographic evaluation is essential, even for asymptomatic individuals, due to its significance in the differential diagnosis of orofacial pain, cervical pain, and Eagle syndrome.</p><p><strong>Clinical significance: </strong>This study provides updated epidemiological evidence within the Dominican context and contributes to the increasing body of knowledge, laying a foundation for future research that connects radiological findings with clinical manifestations.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 3","pages":"237-241"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148227875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Considerations to Establish the Best Orientation of the Occlusal Plane Used in Oral Rehabilitation: A Systematic Review.","authors":"Daysi S Neyra-Quilca, Luis E Arriola-Guillén","doi":"10.5005/jp-journals-10024-4039","DOIUrl":"10.5005/jp-journals-10024-4039","url":null,"abstract":"<p><strong>Aim: </strong>The goal of this review was to compile all available information in an updated literature review to indicate the correct position of the tragus on Camper's plane and other considerations to establish the best orientation of the occlusal plane used in oral rehabilitation.</p><p><strong>Materials and methods: </strong>A comprehensive search was conducted by two trained reviewers across the primary data sources, including Medline via PubMed, ScienceDirect, Scopus, EBSCO, and SciELO. The search employed the keywords \"(orientation) AND (dental occlusion OR occlusal plane OR Camper plane)\" and covered the period from May 2018 to November 2025. The risk of bias for all selected articles was evaluated using the Newcastle-Ottawa Scale. The analysis focused on identifying the optimal orientation of the occlusal plane for use in oral rehabilitation.</p><p><strong>Results: </strong>A total of 1,710 articles were identified, of which only 14 were included for analysis. Seven articles had a low risk of bias. Moreover, these studies indicated that the ideal location for the posterior point of Camper's plane, when aligned with the tragus, results in an occlusal plane that runs parallel to it, connecting the lower border of the wing of the nose to the lower part of the tragus. This outcome remains consistent regardless of the patient's arch shape, clinical judgment, esthetics, or the stability of the restoration. Photography is considered the most widely used method for reconstructing the occlusal plane.</p><p><strong>Conclusion: </strong>The reviewed articles considered the most inferior point marked on the tragus, which would be the most appropriate for the occlusal plane in edentulous and dentate patients. Photography is the most widely used technique for determining the occlusal plane, as it is the most studied and used by clinicians.</p><p><strong>Clinical significance: </strong>Clinicians can accurately determine the occlusal plane in oral rehabilitation by locating the tragus in its optimal orientation using Camper's plane, which serves as the most stable reference for establishing the occlusal plane.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 3","pages":"325-334"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148228537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Shear Bond Strength of MTA and ApaCal ART Liners to a Universal Bonding Agent: An <i>In Vitro</i> Study.","authors":"Angel Kurian, Banibrata Lahiri, Archana A Thomas, Gautham Anilkumar, Fawaz Pullishery, Reshma Raju","doi":"10.5005/jp-journals-10024-4031","DOIUrl":"10.5005/jp-journals-10024-4031","url":null,"abstract":"<p><strong>Aim: </strong>The current investigation sought to assess the shear bond strength (SBS) between two distinct liners and a universal bonding agent.</p><p><strong>Materials and methods: </strong>Eighty extracted premolars were cleaned using a periodontal scaler and stored in 0.9% saline until required. Teeth were cut to expose the dentinal surface at a depth of 1 mm using a straight fissure bur. For uniformity, grooves were marked at 1 mm. Then, use a straight fissure bur to create a 1.5 × 3 × 3 mm hollow on the surface. Apply the mineral trioxide aggregate (MTA) to 40 premolar cavities using an amalgam carrier. Apply the ApaCal ART to 40 premolar cavities, then allow it to cure for 40 seconds. Group IA consisted of 10 premolars bonded with MTA liner using a seventh-generation bonding agent; group IB consisted of 10 premolars bonded with ApaCal ART liner using a seventh-generation bonding agent; group IIA consisted of 10 premolars bonded with MTA liner using an eighth-generation bonding agent; and group IIB consisted of 10 premolars bonded with ApaCal ART liner using an eighth-generation bonding agent. Composite was applied to each sample's cavity lining using a two-layer incremental approach after the adhesive was applied. Each layer was cured. Shear bond strength was assessed by using a universal testing machine.</p><p><strong>Results: </strong>Group IIA had the greatest SBS value (14.9780 MPa), and group IB had the least SBS value (12.3110 MPa). Overall analysis of variance (ANOVA) showed significant differences (<i>p</i> = 0.036), though pairwise comparisons were not statistically significant.</p><p><strong>Conclusion: </strong>In both bioactive materials, the eighth-generation adhesives are superior to the seventh-generation adhesives, with MTA exhibiting greater values.</p><p><strong>Clinical significance: </strong>The lifespan and durability of the repair are guaranteed by a strong enough adhesion between the adhesive system and the liner. Stronger adhesion, which can enhance the stability of the restorative material, prevent marginal gaps, and reduce microleakage.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 3","pages":"254-259"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148228515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Various Finishing and Polishing Environments on the Surface Roughness and Microleakage of Composite Restorations: An <i>In Vitro</i> Study.","authors":"Ashok Kumar, Ibadat P Kaur","doi":"10.5005/jp-journals-10024-4038","DOIUrl":"10.5005/jp-journals-10024-4038","url":null,"abstract":"<p><strong>Aim: </strong>Finishing and polishing (FaP) are essential procedures that significantly affect the long-term clinical performance of composite restorations; however, their efficacy under varying environmental conditions remains insufficiently elucidated. This study aims to evaluate the impact of dry, wet, and combined FaP sequences on surface roughness (Ra) and microleakage of composite restorations.</p><p><strong>Materials and methods: </strong>A total of 57 premolars were randomly assigned to five groups: Control (Cg, <i>n</i> = 11), dry (Dg, <i>n</i> = 12), wet (Wg, <i>n</i> = 12), dry-followed-by-wet (DfWg, <i>n</i> = 11), and wet-followed-by-dry (WfDg, <i>n</i> = 11) group. Finishing was performed in all except Cg using a specified four-step sequence, i.e., fine diamond bur, white stone, and fine and extra-fine Sof-Lex discs. Surface roughness was measured using a profilometer, while dual microleakage evaluation was performed by recording microleakage scores (Ms) under a stereomicroscope (40×), and actual microleakage depths (Md) using a Tool Maker's microscope (30×).</p><p><strong>Results: </strong>Statistical analysis was conducted using the Kruskal-Wallis and Mann-Whitney tests. Intergroup comparisons revealed no significant differences in Ra values (<i>p</i> = 0.136). However, statistically significant differences were observed in Ms and Md values along both the occlusal (<i>p</i> = 0.002) and gingival margins (<i>p</i> = 0.000). Pairwise comparisons showed significantly smoother surfaces in Wg vs Dg (<i>p</i> = 0.04), with additional significant differences in microleakage between Cg-Dg, Cg-DfWg (both margins), and Wg-DfWg (gingival margin).</p><p><strong>Conclusion: </strong>The finishing of composite restorations under wet environmental conditions is somewhat beneficial with respect to surface roughness and microleakage.</p><p><strong>Clinical significance: </strong>This study describes the use of a standardized approach to assess the influence of varied environmental conditions on FaP outcomes. The findings provide clinically relevant insights that may further improve procedural efficiency, optimize surface quality, and enhance the longevity of composite restorations.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 3","pages":"260-268"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148228497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Intercondylar Distance as a Predictor of Vertical Dimension in Edentulous Patients: A Cross-sectional Comparative Study.","authors":"Madhu Ranjan, Surender Kumar, Shivani Singh, Amit V Mahuli, Priya Rani, Ghazala Khurshid","doi":"10.5005/jp-journals-10024-3968","DOIUrl":"10.5005/jp-journals-10024-3968","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to evaluate the applicability of intercondylar distance (ICD) measurement in determining the vertical dimension of occlusion in edentulous patients.</p><p><strong>Materials and methods: </strong>The first part of the study included 250 dentulous individuals visiting the departmental OPD and the students of the institute (aged 18-40 years) of both genders. Intercondylar distance was measured at the Denar reference point, and occlusal vertical dimension (OVD) was measured between the subnasion and the gnathion during maximum intercuspation. A regression equation was formulated based on the ICD-OVD relationship. The second part involved 40 edentulous patients (20 males, 20 females). Occlusal vertical dimension was assessed using conventional methods (OVD1) and the ICD-based method (OVD2), and their agreement was analyzed.</p><p><strong>Results: </strong>The first part of the study revealed a significant relationship between ICD-OVD (<i>p</i> < 0.001) with a 0.319 mm OVD increase per 1 mm ICD increase in dentulous participants. However, the second part of the study showed a low concordance correlation coefficient (CCC = 0.243) with a mean bias of -0.773 mm in edentulous participants. Gender differences in OVD were significant (<i>p</i> < 0.001), with males showing higher values than females in edentulous participants.</p><p><strong>Conclusion: </strong>Despite low concordance with conventional methods, the ICD method for determining OVD has shown consistent applicability across genders and edentulous durations, thus underscoring its clinical relevance.</p><p><strong>Clinical significance: </strong>Determining the OVD in complete dentures lacks a universal method. The ICD-OVD relationship and its application in edentulous patients remain unclear. Individual differences in recording the OVD using the conventional method can be eliminated with the implementation of the ICD-based method. This method holds clinical promise across genders and edentulous durations.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 3","pages":"248-253"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148228492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scientometric Analysis on the Application of Chlorhexidine Chips in Periodontics and Oral Implantology.","authors":"Fran Espinoza-Carhuancho, Mabel Huaman-De la Cruz, Ivan Calderon, Cesar Mauricio-Vilchez, Felipe Lozano, Frank Mayta-Tovalino","doi":"10.5005/jp-journals-10024-4041","DOIUrl":"10.5005/jp-journals-10024-4041","url":null,"abstract":"<p><strong>Aim: </strong>To perform a scientometric analysis to map and characterize the scientific production on chlorhexidine locally delivered devices, particularly chlorhexidine chips, in periodontics and oral implantology from 2015 to 2025.</p><p><strong>Materials and methods: </strong>A descriptive bibliometric study of scientific publications indexed in Scopus was conducted according to the RAMIBS framework to enhance transparency and reproducibility. A structured search strategy was developed using terms relating to chlorhexidine chips and other local delivery devices. Bibliographic metadata were exported in comma separated value (CSV) format and analyzed using standard bibliometric techniques to map scientific productivity and collaboration and explore keyword co-occurrence networks and themes over time.</p><p><strong>Results: </strong>On December 2, 2025, overall 33 documents published in 26 sources are identified with -14.8% of annual growth and high citation impact (30.9 citations/article). The research landscape was characterized by collaborative authorship structure with 188 unique authors and 18.1% of publications are international collaborations. Highly cited, high-impact publications were produced by institutions with a strong track record of academic visibility, including authors from Harvard University, Columbia University and Madrid's Complutense University. Core publishing venues included the Journal of Clinical Periodontology (CiteScore 12.2) and Journal of Periodontology (CiteScore 9.4) which emerged as the leading sources. Thematic keyword co-occurrence analysis identified chlorhexidine as the central thematic axis.</p><p><strong>Conclusions: </strong>This scientometric analysis shows that research on chlorhexidine devices for local delivery, in particular, chlorhexidine chips from 2015 to 2025 is fairly scarce but consolidated with a declining trend in publications, showing high impact, and with a stable thematic focus on periodontal and peri-implant outcomes.</p><p><strong>Clinical significance: </strong>These findings indicate that research on dedicated chlorhexidine local delivery devices represents a mature field with a stable level of productivity, stability in collaborators and citation impact. This thematic structure highlights the importance of chlorhexidine in an interdisciplinary research area covering periodontal treatment, biomaterials, and drug delivery.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 3","pages":"318-324"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148227860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Fracture Resistance of Tooth Fragment Reattached with Cavity Disinfectants in Primary and Permanent Teeth: An <i>In Vitro</i> Study.","authors":"Komal P Bhosale, Vishnu R Chamarthi, Dhanraj Kalaivanan, Santham Krishnamoorthy, Sumaiyya Saleem, Akr Santhosh Priya, Sai Sk Kothimbakkam","doi":"10.5005/jp-journals-10024-4027","DOIUrl":"https://doi.org/10.5005/jp-journals-10024-4027","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study is to evaluate the effect of 2% chlorhexidine digluconate and a combination of 2.5% sodium hypochlorite with 10% ascorbic acid on fracture resistance of reattached fragments in primary and permanent anterior teeth.</p><p><strong>Materials and methods: </strong>An <i>in vitro</i> study was conducted on 102 extracted human anterior teeth (51 primary and 51 permanent), allocated into six groups (<i>n</i> = 17): Group A (primary incisors)-Conventional fragment reattachment, group B (primary incisors)-Chlorhexidine pretreatment, group C (primary incisors)-Sodium hypochlorite + ascorbic acid pretreatment, group D (permanent incisors)-Conventional fragment reattachment, group E (permanent incisors)-Chlorhexidine pretreatment, and group F (permanent incisors)-Sodium hypochlorite + ascorbic acid pretreatment. All specimens underwent standardized bonding, thermocycling (1,000 cycles, 5-55°C), and fracture testing in a universal testing machine. Data were analyzed with one-way analysis of variance (ANOVA) (SPSS v25, IBM, USA).</p><p><strong>Results: </strong>In primary teeth, sodium hypochlorite-ascorbic acid showed the highest mean fracture resistance (54.63 ± 10.70 N), followed by chlorhexidine (52.43 ± 12.38 N) and conventional reattachment (43.19 ± 9.38N), with statistically significant differences. In permanent teeth, chlorhexidine demonstrated the highest mean value (151.63 ± 25.05 N), followed by conventional reattachment (145.73 ± 29.08 N) and sodium hypochlorite-ascorbic acid (130.92 ± 20.15 N), with no statistically significant differences among groups.</p><p><strong>Conclusion: </strong>Cavity disinfectants improve fracture resistance of reattached fragments, particularly in primary teeth. Sodium hypochlorite with ascorbic acid enhances bonding in primary dentition, while chlorhexidine provides consistent performance in both dentitions.</p><p><strong>Clinical significance: </strong>Appropriate selection of cavity disinfectants based on dentition can improve the clinical success of fragment reattachment. Sodium hypochlorite followed by ascorbic acid may be beneficial in primary teeth by enhancing fracture resistance, while chlorhexidine can be safely used in permanent teeth without adversely affecting bond strength. This approach may contribute to improved longevity of restorations in pediatric trauma management.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 3","pages":"269-273"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148228524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}