Journal of Contemporary Dental Practice最新文献

{"title":"Are Salivary Cortisol Levels Elevated in Periodontitis Patients Experiencing Stress Compared to Those without Stress? A Systematic Review and Meta-analysis.","authors":"Mohammed S Al-Ak'hali, Essam A Al-Moraissi, Hytham N Fageeh, Hani S Alakhali, Syed W Peeran, Turki A Khurayzi, Abdullah G Imran","doi":"10.5005/jp-journals-10024-3819","DOIUrl":"10.5005/jp-journals-10024-3819","url":null,"abstract":"<p><strong>Aim and background: </strong>This meta-analysis aims to systematically assess the association between periodontitis and stress in relation to salivary cortisol levels.</p><p><strong>Methods: </strong>Four major databases, the MEDLINE-PubMed, Google Scholar, EMBASE, and CENTRAL databases, were searched from January 2005 to August 2023 for prospective and retrospective clinical studies. The PECO guidelines followed were as follows: Population: Patients with periodontal disease; Exposure: depression, stress, or anxiety; comparison: No periodontal disease and no depression, stress, or anxiety; outcome: salivary cortisol level. The following variables were extracted from each study: author, study design, sample size, saliva cortisol level (mean), periodontal parameters, method of stress evaluation, and the outcome of the study. The risk of bias was evaluated using the Newcastle-Ottawa Scale. The statistical analysis involved calculating standardized mean differences (SMD) and their corresponding 95% confidence intervals (CI). The meta-analysis was conducted using comprehensive meta-analysis version 2.</p><p><strong>Results: </strong>A total of 101 articles were identified, of which 73 articles were excluded after the first round of screening of titles and abstracts and 17 articles were excluded after full-text examination. Finally, 11 clinical studies comprising of 1,565 participants that satisfied the inclusion criteria for the systematic review were considered. While eight studies were included for meta-analysis in the first comparison group and seven studies were considered for analysis in the second comparison group. Of the 11 studies included in the present systematic review, seven were cross-sectional studies, three were case-control studies, and one was randomized double-blinded prospective study. The meta-analysis findings indicated a statistically significant increase in cortisol levels among patients with periodontitis compared to those without periodontitis (SMD = -1.424, CI: -2.107 to -0.740, <i>p</i> = 0.001, low-quality evidence). Moreover, a statistically significant increase in cortisol levels was observed in patients with periodontitis who experienced stress.</p><p><strong>Conclusion: </strong>Overall studies included in the review demonstrate and confirm a positive association between elevated salivary cortisol levels and periodontitis with stress.</p><p><strong>Clinical significance: </strong>The results of this study suggest that treatment for periodontitis patients could be tailored to consider both the clinical aspects of the condition and the patient's stress levels. Thus, clinicians should pay attention to stress management as part of comprehensive periodontal care. How to cite this article: Al‑Ak'hali MS, Al-Moraissi EA, Fageeh HN, <i>et al.</i> Are Salivary Cortisol Levels Elevated in Periodontitis Patients Experiencing Stress Compared to Those without Stress? A Systematic Review and Meta-analysis. J Contemp Dent P","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"26 2","pages":"206-216"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Frictional Resistance in Different Bracket Systems with Different Orthodontic Archwires: An <i>In Vitro</i> Study.","authors":"Fahad K Al-Dulaimi, Nehal F Albelasy, Mohammad H Mohammad, Ahmed M Hafez","doi":"10.5005/jp-journals-10024-3825","DOIUrl":"10.5005/jp-journals-10024-3825","url":null,"abstract":"<p><strong>Aim: </strong>This study evaluated the static frictional resistance of different self-ligating brackets (SLBs) and a conventional stainless steel (SS) bracket with two different archwire alloys during sliding mechanics.</p><p><strong>Materials and methods: </strong>A total of 96 maxillary canine brackets were divided into four groups (24 Mini Diamond^TM conventional SS brackets, 24 Damon^TM Q2 metal passive SLBs, 24 Empower^TM 2 metal active SLBs, and 24 Damon^TM Clear 2 ceramic passive SLBs). These were tested with SS and titanium-molybdenum alloy (TMA) archwires, each measuring 0.019 × 0.025 in. The frictional resistances were measured using a Universal Testing Machine as the brackets were drawn vertically along the straight segments of the archwire. A two-way analysis of variance (ANOVA), a one-way ANOVA with a <i>post-hoc</i> Tukey test, and a Student <i>t</i>-test were used for statistical analysis.</p><p><strong>Results: </strong>The lowest mean of static frictional resistance was observed in two passive bracket groups, followed by active group and conventional group. Significant differences were found between bracket groups with SS and TMA archwires (<i>p</i> < 0.001), except between two passive groups, where no significant differences were found (SS: <i>p</i> = 0.193, TMA: <i>p</i> = 0.415). Among the archwires, the TMA had significantly higher static frictional resistance than SS with Mini Diamond^TM (<i>p</i> < 0.001) and Empower^TM 2 (<i>p</i> < 0.001), while there were no significant differences in frictional resistance between the SS and TMA archwires with Damon^TM Q2 (<i>p</i> = 0.145) and Damon^TM Clear2 (<i>p</i> = 0.470).</p><p><strong>Conclusion: </strong>The selection of bracket systems and wire material significantly influences the frictional resistances in sliding mechanics. When TMA archwires are used for sliding mechanics, passive appliances can minimize frictional resistances.</p><p><strong>Clinical significance: </strong>The frictional resistances at the bracket-archwire-ligation connection significantly influence orthodontic tooth movement, which in turn affects treatment time. This study assesses the frictional resistances of different SLBs and conventional brackets with different archwires, which allows orthodontists to select the most effective bracket/archwire combination for minimizing frictional resistances. How to cite this article: Al-Dulaimi FK, Albelasy NF, Mohammad MH, <i>et al.</i> Evaluation of Frictional Resistance in Different Bracket Systems with Different Orthodontic Archwires: An <i>In Vitro</i> Study. J Contemp Dent Pract 2025;26(2):137-143.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"26 2","pages":"137-143"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Biocompatibility of Novel Green-synthesized Nano-modified Glass Ionomer Cement: A Biochemical and Histopathological Analysis Study in Wistar Albino Rats.","authors":"Harini Palani, Jessy Paulraj, Subhabrata Maiti, M Karthick Ganesh","doi":"10.5005/jp-journals-10024-3830","DOIUrl":"10.5005/jp-journals-10024-3830","url":null,"abstract":"<p><strong>Aim: </strong>The study aims to evaluate the biocompatibility of novel green-synthesized nano-modified glass ionomer cement (GIC) in Wistar albino rats.</p><p><strong>Materials and methods: </strong>Green-synthesized chitosan, titanium, zirconia, and hydroxyapatite (HA) nanoparticles were incorporated into the GIC powder, and nine disc-shaped modified GIC specimens with a diameter of 5 mm and a thickness of 2 mm were fabricated. The specimens were then implanted subcutaneously in the dorsal region of 18 Wistar albino rats. Group I received conventional GIC (<i>n</i> = 9), while group II received nano-modified GIC (<i>n</i> = 9). Biochemical analyses were conducted at 3, 10, and 30-day intervals, with three animals per group assessed at each time point with the same animals. Similarly, histopathological evaluations were performed at the same intervals, with three animals from each group examined at each time point. Blood biochemical analysis, including serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), urea, and creatinine, as well as histopathological examinations using H&E and Masson's trichrome stains, were performed at 3, 10, and 30-day intervals. The collected data were statistically analyzed.</p><p><strong>Results: </strong>Biochemical analysis at day 30, liver function markers, SGOT (Group I: 51.07 ± 0.725, group II: 52.63 ± 3.298) and SGPT (Group I: 45.32 ± 1.950, group II: 46.36 ± 4.288), showed no significant differences. Renal function tests (RFTs) also revealed no significant differences in creatinine (Group I: 0.54 ± 0.001, group II: 0.63 ± 0.145) and urea (Group I: 40.76 ± 0.333, group II: 42.31 ± 3.082). Histopathological analysis at 10 days for group II revealed more favorable tissue repair, characterized by an increased number of fibroblasts and fewer macrophages. At 30 days, the test specimens in group II were surrounded solely by fibroblasts, with no signs of inflammation.</p><p><strong>Conclusion: </strong>The results of this study concluded that both groups exhibited satisfactory biocompatibility, with the green-synthesized nano-modified glass ionomers demonstrating more advanced tissue repair. The biochemical parameters in both groups remained within the normal reference ranges, indicating no signs of toxicity.</p><p><strong>Clinical significance: </strong>Conventional GIC has a good ability to bond to tooth structure, but its limitations often reduce the durability and long-term success of restorations. The green-synthesized nano-modified GIC enhances biocompatibility by reducing the risk of inflammation and toxicity, making it a more reliable and long-lasting option for restorations. How to cite this article: Palani H, Paulraj J, Maiti S, <i>et al.</i> Evaluating the Biocompatibility of Novel Green-synthesized Nano-modified Glass Ionomer Cement: A Biochemical and Histopathological Analysis Study in Wistar Albino Rats. J Contemp Dent Pract 2025;26(2):192-199.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"26 2","pages":"192-199"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral Health and the Role of Medical Social Workers: Still Necessary, and How should We Think about Their Role?","authors":"Mohd Manshoor Ahmed, Jilly John","doi":"10.5005/jp-journals-10024-3734","DOIUrl":"10.5005/jp-journals-10024-3734","url":null,"abstract":"<p><p>How to cite this article: Ahmed MM, John J. Oral Health and the Role of Medical Social Workers: Still Necessary, and How should We Think about Their Role? J Contemp Dent Pract 2025;26(2):117-118. Keywords: Health equity, Medical social workers, Multidisciplinary care, Oral health.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"26 2","pages":"117-118"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating Lip Repositioning for the Treatment of Excess Gingival Display with and without Pretreatment with Botox: A Randomized Clinical Trial.","authors":"Ola M Ghoniem, Gehan G Madkor, Mona S Darhous","doi":"10.5005/jp-journals-10024-3831","DOIUrl":"10.5005/jp-journals-10024-3831","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate and compare the treatment of excessive gingival display (EGD) with lip repositioning surgery (LRS), with or without presurgical Botox injection, using relapse as the primary outcome.</p><p><strong>Materials and methods: </strong>Twenty-two periodontally healthy patients with EGD were recruited and allocated into two equal groups. The intervention group (<i>n</i> = 11) underwent LRS with Botox preinjection into the smile muscles 1-2 weeks before surgery, while the control group (<i>n</i> = 11) underwent only LRS. Participants were assessed for changes in gingival display and lip length at 3, 6, 9, and 12 months, as well as for pain and satisfaction. The data were recorded and statistically analyzed.</p><p><strong>Results: </strong>The control group showed a statistically significant change in gingival display at 3 months (3.82 ± 2.09 mm) and 6 months (4.68 ± 1.72 mm) compared to baseline (5.91 ± 1.45 mm), but no significant changes at 9 months (5.55 ± 1.37 mm) and 12 months (5.64 ± 1.50 mm). The intervention group demonstrated a significant reduction in gingival display at 3 months (2.23 ± 1.29 mm) and 6 months (3.95 ± 1.39 mm), with stable results up to 12 months (4.27 ± 1.10 mm). The overall reduction in gingival display was significantly greater in the intervention group compared to the control group (1.86 mm, 0.27 mm, respectively). Patient satisfaction with the treatment was not significantly different between the two groups, except for willingness to repeat the procedure. Pain scores were significantly higher in the control group than in the Botox group at 24 h, with no significant differences at 3 and 7 days.</p><p><strong>Conclusions: </strong>Botox pre-injection for LRS demonstrated its efficacy for management of EGD by enhancing lip length, reducing relapse, alleviating postoperative discomfort, and providing sustained results for 1 year.</p><p><strong>Clinical significance: </strong>This study addresses effective treatments for EGD, improving esthetics and confidence. By evaluating LRS with and without Botox, it offers practical insights that improves EGD and reduces relapse, resulting in increased patient satisfaction and sustained results over a year. How to cite this article: Ghoniem OM, Madkor GG, Darhous MS. Evaluating Lip Repositioning for the Treatment of Excess Gingival Display with and without Pretreatment with Botox: A Randomized Clinical Trial. J Contemp Dent Pract 2025;26(2):119-126.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"26 2","pages":"119-126"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osseointegration of Dental Implants in Irradiated Patients: A Bibliometric Study.","authors":"Jean Montoya-Mercado, Rosabelle García-Herencia, Pedro L Tinedo-López, Fran Espinoza-Carhuancho, Josmel Pacheco-Mendoza, Frank Mayta-Tovalino","doi":"10.5005/jp-journals-10024-3823","DOIUrl":"10.5005/jp-journals-10024-3823","url":null,"abstract":"<p><strong>Background: </strong>To analyze the osseointegration of dental implants in irradiated patients through a bibliometric study.</p><p><strong>Materials and methods: </strong>A descriptive and retrospective bibliometric study was conducted, focusing on English-language scientific publications indexed in Scopus from January 2018 to May 2024. To maintain quality and relevance, the study excluded abstracts, letters to the editor, book reviews, opinions, and symposium reports. The search, conducted on May 11, 2024, utilized the MeSH terms from the National Library of Medicine along with Boolean operators to refine the search. Relevant indicators such as citation count, publications by country, year, author, journal quartile, and more were examined. The data were analyzed using SciVal, Mendeley, Bibliometrix, and VOSviewer software.</p><p><strong>Results: </strong>The research identified 25 relevant papers, with an annual growth rate of 16.73%. The average number of citations per paper was 9.8, with a total of 846 references and 144 authors. German institutions led in scientific production, with the highest impact seen at Hospital Santa Catarina of Brazil. Brazilian authors showed the highest citation impact, while Heiland Max attained the highest h-index. Most publications were within the first (Q1, <i>n</i> = 14) and second (Q2, <i>n</i> = 6) quartiles, with 2021 standing out as the year with the highest impact. Collaboration maps highlighted international cooperation between several countries such as the USA, Spain, China, and Chile.</p><p><strong>Conclusion: </strong>The study provides a comprehensive bibliometric analysis of osseointegration of dental implants in irradiated patients, highlighting key trends and collaborations in the field.</p><p><strong>Clinical significance: </strong>This study underscores the clinical importance of osseointegration of dental implants in patients who have undergone radiation therapy. By providing insights into trends and collaborative networks, enhances our understanding of these patterns, which can improve treatment strategies, and patient outcomes, and guide future research. Ultimately, this advances the field of dental implantology for irradiated patients. How to cite this article: Montoya-Mercado J, García-Herencia R, Tinedo-López PL, <i>et al.</i> Osseointegration of Dental Implants in Irradiated Patients: A Bibliometric Study. J Contemp Dent Pract 2025;26(2):217-222.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"26 2","pages":"217-222"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of the Histological Characteristics in Various Teeth of Different Age-groups: An Observational <i>In Vitro</i> Study.","authors":"Shubhi Gupta, Saurav Bathla, Madhusudan Astekar","doi":"10.5005/jp-journals-10024-3832","DOIUrl":"10.5005/jp-journals-10024-3832","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To assess the prevalence and distribution of enamel lamellae, enamel tufts, and incremental lines in different tooth types (incisors, canines, premolars, and molars) across various age-groups (≤20, 21-40, 41-60, and 60 and above) using histological analysis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;A total of 200 extracted human permanent teeth from individuals were collected and categorized into four groups, based on age-group I (≤20 years), group II (21-40 years), group III (41-60 years) and group IV (&gt;60 years) including various tooth types such as incisor, canine, premolar and molars, respectively. Teeth were manually sectioned longitudinally using a carborundum disk and examined under a light microscope (10× magnification) to assess enamel lamellae, enamel tufts, enamel spindles, interglobular dentin, the cementoenamel junction (CEJ), and incremental lines in cementum. Data were analyzed using the Chi-square (χ²) test to determine statistical significance.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Molars were the most examined teeth (37.0%), followed by premolars (25.5%), canines (22.5%), and incisors (15.0%). Enamel lamellae were mostly grade II (43.3%) with no significant variation by age (&lt;i&gt;p&lt;/i&gt; = 0.261) or tooth type (&lt;i&gt;p&lt;/i&gt; = 0.653). Type A enamel lamellae (91.5%) did not differ significantly by tooth type (&lt;i&gt;p&lt;/i&gt; = 0.237) or age (&lt;i&gt;p&lt;/i&gt; = 0.871). The extent was primarily type E2 (72.0%) with no significant differences (&lt;i&gt;p&lt;/i&gt; &gt; 0.05). Enamel tufts were mostly type M1/3 (71.5%) with no age (&lt;i&gt;p&lt;/i&gt; = 0.313) or tooth type association (&lt;i&gt;p&lt;/i&gt; = 0.413). Enamel spindles (79%) increased with age (&lt;i&gt;p&lt;/i&gt; = 0.011) and with tooth type (&lt;i&gt;p&lt;/i&gt; = 0.029). Interglobular dentin (77.5%) increased significantly with age (&lt;i&gt;p&lt;/i&gt; &lt; 0.001) but not tooth type (&lt;i&gt;p&lt;/i&gt; = 0.871). GAP type was the most common CEJ type (55.5%) with significant differences (&lt;i&gt;p&lt;/i&gt; &lt; 0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The study concluded that enamel lamellae and tufts showed no significant variation with age or tooth type. Enamel spindles increased with age and tooth type, while interglobular dentin increased with age but not tooth type. The most common CEJ type was GAP, with significant differences observed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical significance: &lt;/strong&gt;Understanding the histological characteristics of enamel lamellae, tufts, and incremental lines in different teeth and age-groups is crucial in endodontics, as these structural variations influence crack propagation, fracture resistance, and treatment outcomes. Age-related changes affect dentin permeability, irrigation efficiency, and obturation success. These advancements play a crucial role in improving restorative and endodontic approaches for enamel preservation and regeneration. How to cite this article: Gupta S, Bathla S, Astekar M. Prevalence of the Histological Characteristics in Various Teeth of Different Age-groups: An Observational &lt;i&gt;In Vitro&lt;/i&gt; Study. J Contemp Dent","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"26 2","pages":"155-162"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association between Body Posture and Malocclusion in Adolescents: A Cross-sectional Study.","authors":"Patricia G Morales-Atarama, Luis E Arriola-Guillén","doi":"10.5005/jp-journals-10024-3807","DOIUrl":"https://doi.org/10.5005/jp-journals-10024-3807","url":null,"abstract":"<p><strong>Aim: </strong>The purpose of this study was to determine the association between body posture and dental malocclusion in adolescents.</p><p><strong>Materials and methods: </strong>This descriptive cross-sectional study evaluated the relationship between malocclusion and body posture in 37 adolescents aged 10-14 who met the selection criteria. A trained and calibrated evaluator assessed malocclusion using Angle's classification and evaluated the severity with the dental esthetic index (DAI). Frontal and lateral body postures were reviewed by a licensed medical technology specialist in physical therapy and rehabilitation using a plumb line, with postures classified as correct or incorrect. Data analysis utilized Chi-square tests and binary logistic regressions (<i>p</i> < 0.05).</p><p><strong>Results: </strong>No association was found between Angle malocclusion and body posture (<i>p</i> = 0.277). However, an association was identified when considering severity, with incorrect frontal posture observed in 77.8% of adolescents with defined malocclusion and 71.4% in those with severe malocclusion (<i>p</i> = 0.035). When malocclusion was regrouped into 2 categories (normal occlusion and malocclusion), a significant association with frontal posture was found (<i>p</i> = 0.035). Logistic regression showed that individuals with defined malocclusion are 9.09-fold more likely to develop improper frontal posture (<i>p</i> = 0.048). Furthermore, when severity was categorized into 2 groups, individuals with malocclusion were found to have a 7.29-fold higher risk of developing incorrect frontal body posture in the position.</p><p><strong>Conclusion: </strong>The severity of malocclusion is associated with incorrect frontal body posture, with individuals with defined malocclusion being more likely to develop improper frontal posture.</p><p><strong>Clinical significance: </strong>Patients with the presence of malocclusion has more risk of developing incorrect frontal body posture. Therefore, orthodontists should consider this relationship when treating their patients. How to cite this article: Morales-Atarama PG, Arriola-Guillén LE. The Association between Body Posture and Malocclusion in Adolescents: A Cross-sectional Study. J Contemp Dent Pract 2025;26(1):48-54.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"26 1","pages":"48-54"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone Remodeling Optimization in Orthodontics: Harnessing Periodontal Ligament Cell-derived Exosomes and Anti-inflammatory Compounds.","authors":"Anwar Shawqi Alhazmi","doi":"10.5005/jp-journals-10024-3816","DOIUrl":"https://doi.org/10.5005/jp-journals-10024-3816","url":null,"abstract":"<p><strong>Aim and background: </strong>Exosomes transport biological information between cells and can influence periodontal tissue remodeling. Particularly, the periodontal ligament cells (PDLCs) receive mechanical stimuli and transmit them via exosomes to osteoblasts and assist in tissue remodeling during the orthodontic treatment.</p><p><strong>Materials and methods: </strong>This study uses computational methods to examine the effects of mechanical force-induced PDLC-transported exosomal micro RNA (miRNA) on osteoblast cells and to identify potential adjuvant therapies during orthodontic treatment.</p><p><strong>Results: </strong>As a result of the investigation, 29 miRNAs were overrepresented in the PDLC-derived exosome, and when transported to osteoblasts, it regulates 3,768 mRNA targets, forming a vital gene interaction network. From the network, the crucial cluster was extracted, which plays a role in FoxO signaling, PI3K-Akt signaling, Ras signaling, and MAPK signaling pathways. Further, the cluster analysis with Cytohubba plug-in identified the <i>basic leucine zipper and W2 domains 1 (BZW1)</i> gene as a key target of miRNAs (hsa-let-7d-5p, hsa-miR-101-3p, and hsa-miR-15b-5p) in osteoblast cells. Molecular docking (MD) of 2,696 anti-inflammatory compounds against <i>BZW1</i> indicates the least binding energy of -6.33 kcal/mol for C₂₁H₂₄N₄O₂ that effectively interacts with <i>BZW1</i> protein. Further molecular mechanics-generalized born model and solvent accessibility analysis showed a free-binding energy of -34.56 kcal/mol for the C₂₁H₂₄N₄O₂-<i>BZW1</i> complex. Finally, molecular dynamics simulation confirms stable confirmation of the C₂₁H₂₄N₄O₂-<i>BZW1</i> complex.</p><p><strong>Conclusion: </strong>Our study stipulates the molecular mechanisms that occurred in osteoblast cells upon mechanical stimuli in PDLC, which is critically useful to the development of adjuvant therapeutic molecules for the benefit of orthodontic treatment.</p><p><strong>Clinical significance: </strong>The crucial mechanism by which exosomes deliver miRNAs to the osteoblast cells capable of inhibiting the significant genes/mRNAs could benefit orthodontic treatment. How to cite this article: Alhazmi AS. Bone Remodeling Optimization in Orthodontics: Harnessing Periodontal Ligament Cell-derived Exosomes and Anti-inflammatory Compounds. J Contemp Dent Pract 2025;26(1):77-85.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"26 1","pages":"77-85"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of Penetrability and Adaptability of Different Fluoride-releasing Pit and Fissure Sealants: An <i>In Vitro</i> Study.","authors":"Nasreen Hassan Albar, Thilla Sekar Vinothkumar, Wejdan Hassan Shibli, Ahlam Mohammed Bakri, Abdulhamid Aidarous Alamir, Apathsakayan Renugalakshmi, Waad Fahmi Khayat, Bassam Zidane","doi":"10.5005/jp-journals-10024-3809","DOIUrl":"https://doi.org/10.5005/jp-journals-10024-3809","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to analyze the penetrability and adaptability of three different fluoride-releasing sealants in different fissure types.</p><p><strong>Materials and methods: </strong>Extracted human premolars (<i>n</i> = 45) were randomly divided into three groups of 15 each and randomly allotted to receive the sealants Fisseal (FS), Helioseal F Plus (HS), and Beautisealant (BS). The sealed samples were sectioned in the buccolingual plane, and the deepest fissures were examined under a scanning electron microscope (SEM). The samples were also observed for the fissure types (I, IK, U, V, and inverted Y). The percentage of penetration (POP) and overall gap (OG) between the sealant and fissure wall were measured from the SEM images using ImageJ software.</p><p><strong>Results: </strong>Group FS exhibited the highest POP (68 ± 29.3%) and the smallest OG (1.0 ± 0.9 µm). The least POP was observed for group BS (52.3 ± 20.3%). The I-type fissure was seen in most of the teeth (33%), and the V-type fissure was the least (18%). The mean OG was significantly less in group FS (one-way analysis of variance; <i>p</i> = 0.046). The mean POP was the highest in group FS, followed by groups HS and BS.</p><p><strong>Conclusion: </strong>This SEM study revealed that FS had relatively superior penetrability and adaptability into the fissures, whereas BS was the least-performing material.</p><p><strong>Clinical significance: </strong>Pits and fissures are harder to clean and more prone to dental caries than smooth surfaces because of their plaque-retentive nature. Fisseal could be clinically recommended to seal the pits and fissures and prevent dental caries, as they are long-lasting, and durable. How to cite this article: Albar NH, Vinothkumar TS, Shibli WH, <i>et al.</i> Comparative Analysis of Penetrability and Adaptability of Different Fluoride-releasing Pit and Fissure Sealants: An <i>In Vitro</i> Study. J Contemp Dent Pract 2025;26(1):55-61.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"26 1","pages":"55-61"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}