Journal of Contemporary Dental Practice最新文献

{"title":"Comparative Evaluation of Vitamin C and Injectable Platelet-rich Fibrin in the Management of Thin Gingival Phenotype: A Split-mouth Randomized Clinical Trial.","authors":"Noha M Abdelhay, Manar T Elzanaty, Riham O Ibrahim","doi":"10.5005/jp-journals-10024-4022","DOIUrl":"10.5005/jp-journals-10024-4022","url":null,"abstract":"<p><strong>Aim: </strong>To compare the clinical efficacy of injectable vitamin C and injectable platelet-rich fibrin (i-PRF), each combined with microneedling (MN), in enhancing gingival thickness (GT) among individuals with a thin gingival phenotype.</p><p><strong>Materials and methods: </strong>This randomized, controlled, split-mouth clinical trial included 16 systemically healthy participants (14 females, 2 males; 18-40 years) presenting with a thin gingival phenotype. In each patient, one side received MN + vitamin C (intervention), and the contralateral side received MN + i-PRF (control). Interventions were performed in three sessions at 7-day intervals. Clinical parameters-GT, keratinized tissue width (KTW), pocket depth (PD), gingival index (GI), and plaque index (PI)-were recorded at baseline, 1, 3, and 6 months. Data were analyzed using two-way repeated measures ANOVA and mixed cumulative linked models (CLMs), with <i>p</i> < 0.05 considered significant.</p><p><strong>Results: </strong>Both groups showed a statistically significant increase in GT over time (<i>p</i> < 0.001). The vitamin C group achieved significantly greater GT at 1 month (1.71 ± 0.29 vs 1.55 ± 0.35 mm; <i>p</i> = 0.007) and 3 months (1.39 ± 0.33 vs 1.26 ± 0.33 mm; <i>p</i> = 0.034), while differences were not significant at 6 months. Keratinized tissue width changes were minimal and comparable between groups. Pocket depth decreased slightly in both groups, with i-PRF showing a significantly lower PD at 6 months (<i>p</i> = 0.040). Both GI and PI improved significantly over time, with vitamin C showing a trend toward greater GI reduction (<i>p</i> = 0.053). No adverse effects were observed, and 92.3% of participants reported high satisfaction.</p><p><strong>Conclusion: </strong>Injectable vitamin C combined with MN is a safe, minimally invasive, and effective approach for improving GT and esthetics in thin periodontal phenotypes, showing comparable long-term outcomes to i-PRF.</p><p><strong>Clinical significance: </strong>Development of newer, less invasive therapeutic approaches that help in the prevention of gingival recession. A thin gingival biotype is more prone to gingival recession and to achieve satisfactory therapeutic results with minimum trauma to tissues of any interventional process. How to cite this article: Abdelhay NM, Elzanaty MT, Ibrahim RO. Comparative Evaluation of Vitamin C and Injectable Platelet-rich Fibrin in the Management of Thin Gingival Phenotype: A Split-mouth Randomized Clinical Trial. J Contemp Dent Pract 2026;27(2):170-178.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 2","pages":"170-178"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147964983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-reported Outcomes of Implant Detector Device Use in Second-stage Dental Implant Surgery.","authors":"Bassam A Hamdi, Bader AlZarea, Mohammed M AlMoaleem, Mohammed A Al-Haboob","doi":"10.5005/jp-journals-10024-4032","DOIUrl":"10.5005/jp-journals-10024-4032","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background and aim: &lt;/strong&gt;Localization of submerged cover screws during second-stage dental implant surgery may require blind probing or extensive flap reflection, potentially increasing tissue trauma and postoperative discomfort. Implant detector devices (IDDs) have recently emerged as chairside adjuncts for implant localization; however, patient-reported outcomes associated with their clinical use remain underexplored. Therefore, this study aimed to evaluate patient-reported outcomes associated with different IDDs during second-stage dental implant surgery.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methodology: &lt;/strong&gt;A prospective observational study was conducted across multiple clinical settings. Adult patients undergoing second-stage exposure of submerged dental implants were consecutively recruited. Implant localization was performed using one of three detector systems (EasyinSmile, Implant Locator iD1, or Spotter) prior to soft-tissue incision. Immediately after surgery, participants completed a structured questionnaire assessing satisfaction, perceived complications, comfort with device use, perceived pain reduction, and willingness to recommend the technology. Associations between detector type and patient-reported outcomes were analyzed using cross-tabulation and Fisher's exact test (α = 0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Fifty-four patients were included. Overall satisfaction was high (87.0%, &lt;i&gt;n&lt;/i&gt; = 47): 35 (64.8%) were very much satisfied, 12 (22.2%) somewhat satisfied, 7 (13.0%) undecided, and none selected either \"not really satisfied\" or \"not at all satisfied.\" Most participants reported comfort with device use (77.8%, &lt;i&gt;n&lt;/i&gt; = 42), and 49 (90.7%) perceived less pain during the detector-assisted procedure. No definite complications were reported, although 15 (27.8%) were unsure. Thirty-three participants (61.1%) indicated willingness to recommend the technology. No statistically significant differences were observed among the three detector systems for any patient-reported outcome (&lt;i&gt;p&lt;/i&gt; &gt; 0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Implant detector devices were associated with high patient-reported satisfaction and a favorable procedural experience during second-stage implant surgery. Outcomes appeared comparable across detector systems; however, because this observational study did not include a conventional control group, superiority over standard localization methods cannot be inferred. Further randomized controlled studies with objective outcomes are needed to confirm these findings.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical significance: &lt;/strong&gt;Implant detector devices may support a more patient-centered second-stage implant procedure by enabling minimally invasive implant uncovering, improving patient comfort and acceptance, and potentially reducing procedural anxiety. How to cite this article: Hamdi BA, AlZarea B, AlMoaleem MM, &lt;i&gt;et al.&lt;/i&gt; Patient-reported Outcomes of Implant Detector Device Use in Second-stage Dental Implant Surgery. J C","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 2","pages":"156-162"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147964981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uncovering Antibiotic Resistance Signatures in Endodontic <i>Enterococcus faecalis</i>.","authors":"Nezar Boreak, Wafa Faqehi, Raghad E Ageeli, Hassan A Sumayli, Taym Ha Khormi, Aeshah M Abuhashem, Abrar A Tairy, Ali Yj Mobarki, Tariq M Qassadi, Calvin Bennion, Shilpa Bhandi","doi":"10.5005/jp-journals-10024-3942","DOIUrl":"10.5005/jp-journals-10024-3942","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Aims and background: &lt;/strong&gt;Due to its resilience and resistance to common intracanal disinfectants and medicines, &lt;i&gt;Enterococcus faecalis,&lt;/i&gt; also known as &lt;i&gt;E. faecalis,&lt;/i&gt; is a notorious pathogen in endodontics that is frequently isolated from persistent and secondary root canal infections. Its growing resistance to antibiotics that target the cell wall is concerning, and its clinical impact on endodontic failure is widely acknowledged. Yet, there remains a lack of comprehensive understanding of the global transcriptional responses that &lt;i&gt;E. faecalis&lt;/i&gt; employs to survive exposure to widely used β-lactams and glycopeptides.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;The Affymetrix &lt;i&gt;E. faecalis&lt;/i&gt; OG1RF array microarray dataset, GSE45306, which comprised 15 samples, was examined, and the untreated controls and cultures were exposed to 10× MIC of Ampicillin, Bacitracin, Cephalothin, and Vancomycin for 30 minutes. Gene expression omnibus 2R (GEO2R)/limma was referred to identify differentially expressed genes (DEGs) after quality control and robust multi-array average (RMA) normalization, using an adjusted &lt;i&gt;p&lt;/i&gt; &lt; 0.05 and |log&lt;sub&gt;2&lt;/sub&gt; fold change| &gt; 1.5. Heatmaps, Venn diagrams, and volcano plots were used to visualize both treatment-specific and shared transcriptional responses.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;With 552 distinct DEGs, Vancomycin caused the biggest transcriptional shift, whereas Cephalothin and Bacitracin affected 77 and 10 genes, respectively. A core set of 55 stress-responsive genes, many of which code for proteins with unclear or poorly understood activities, was shown to be consistently changed across all antibiotic treatments. Common themes revealed by pathway, and expression analysis included increased expression of efflux transporters, metabolic changes, especially involving Adenosine triphosphate (ATP) synthase and pyruvate dehydrogenase, and cell wall remodeling. Furthermore, a number of regulators particular to antibiotics, such as membrane-associated sensors and members of the cell envelope-associated transcriptional attenuator LytR-CpsA-Psr family, indicated specific adaptation mechanisms.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;&lt;i&gt;Enterococcus faecalis&lt;/i&gt; has a sophisticated, adaptable transcriptional response to antibiotic stress, as well as drug-specific and transparently preserved survival strategies.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical significance: &lt;/strong&gt;During endodontic treatment, the antibiotic-specific transcriptional regulators, such as &lt;i&gt;E. faecalis&lt;/i&gt;-membrane-associated sensors and members of the LytR-CpsA-Psr family, undergo adaptive responses. Thus, to enhance root canal disinfection and fight antibiotic resistance, these molecular targets are considered the most promising aspects of acumen. How to cite this article: Boreak N, Faqehi W, Ageeli RE, &lt;i&gt;et al.&lt;/i&gt; Uncovering Antibiotic Resistance Signatures in Endodontic &lt;i&gt;Enterococcus faecalis.&lt;/i&gt; J Contemp Dent Pract 2026;27(2):130","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 2","pages":"130-140"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147964996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Hydroxyapatite Seashell Nanofiller on Some Properties of Autopolymerized Acrylic Material for Orthodontic Appliances.","authors":"Afrah K Ai Hamdany, Zaid S Tawfek, Neam F Agha, Banan N Alhussary","doi":"10.5005/jp-journals-10024-4033","DOIUrl":"10.5005/jp-journals-10024-4033","url":null,"abstract":"<p><strong>Aim: </strong>This study investigated the effect of adding bioactive biocompatible seashell-derived hydroxyapatite (HA) nanofillers on the mechanical properties of acrylic polymethyl methacrylate (PMMA) resin, namely flexural strength, hardness, and compressive strength.</p><p><strong>Materials and methods: </strong>Sixty acrylic specimens were divided into four groups, with five acrylic specimens for each test; control and experimental specimens containing 5, 10, and 12% seashell nanoparticles (NPs) added to the acrylic. The tests included hardness, compression strength, and flexural strength. According to the required proportion of NPs, these NPs were added to the monomer (liquid) of the cold-cured acrylic resin. The specimens were removed to complete the preparation process and then stored in distilled water at 37°C for 48 hours before testing. Data were analyzed using SPSS software. The difference was considered statistically significant at a <i>p</i>-value ≤ 0.05. For descriptive analysis of all variables, a paired <i>t</i>-test was used to compare the control group with the experimental groups.</p><p><strong>Results: </strong>For hardness and compression strength, the highest mean values for the groups were 12, 10, and 5%, respectively. For flexural strength, the 12% group was higher than the control group, followed by the 10% group, and then the 5% group, which was lower than the control group. A significant difference was found between the control group at both 5 and 12% for flexural strength, and a significant difference was also found between the control group at both 5 and 10% for hardness, and across all concentration groups for compression.</p><p><strong>Conclusion: </strong>Adding a high concentration of seashell HA NP largely increased the flexural strength of PMMA resin. Cold-cured PMMA resin incorporated with lower concentrations of seashell HA NPs noticeably revealed improved hardness. Seashell HA NPs at the studied three concentrations improved the compression strength of the cold-cured PMMA resin.</p><p><strong>Clinical significance: </strong>Natural HA NPs from seashell can be used as a bio-compatible nanofiller that can strengthen self-curing polymer materials. How to cite this article: Al Hamdany AK, Tawfek ZS, Agha NF, <i>et al.</i> Effect of Hydroxyapatite Seashell Nanofiller on Some Properties of Autopolymerized Acrylic Material for Orthodontic Appliances. J Contemp Dent Pract 2026;27(2):141-147.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 2","pages":"141-147"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147964961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facial Photography vs Cephalometry for Assessing Jaw Discrepancies: A Systematic Review.","authors":"Shella I Novianty, Ananto A Alhasyimi, Anne H Dewi, Niswati F Rosyida","doi":"10.5005/jp-journals-10024-4028","DOIUrl":"10.5005/jp-journals-10024-4028","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To systematically review studies to evaluate the correlation and agreement between facial photographic measurements and cephalometric parameters in assessing jaw discrepancy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;An extensive search was performed in PubMed, Scopus, and Web of Science to retrieve articles published from January 2015 to December 2024, and the literature search itself was conducted from 2 to 20 December 2024. The systematic review was carried out following the PRISMA 2020 guidelines. The participants, intervention, control, and outcome (PICO) framework used was as follows: (P) Orthodontic patients who underwent cephalometric and facial photographic assessment; (I): Cephalometric measurements derived from standardized 2D lateral facial photographs; (C): Cephalometric measurements obtained from lateral cephalograms; (O): Agreement between photographic and cephalometric parameters, evaluated through correlation coefficient, agreement statistics, or diagnostic accuracy measures (sensitivity/specificity); and (S): Observational correlation studies and diagnostic accuracy studies. The data extracted comprised study design, participant details, measurement parameters, and outcome statistics. Data extraction and quality appraisal were performed independently by two reviewers using the Joanna Briggs Institute (JBI) diagnostic test accuracy checklist.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 83 studies were screened, of which seven studies met the inclusion criteria, comprising six cross-sectional and one prospective design. Risk of bias (ROB) assessment indicated an overall low to moderate risk. Most studies reported clear inclusion criteria and applied both index and reference tests within the same session. However, blinding of assessors was frequently unclear, introducing potential interpretation bias. Photographic measurements showed significant correlations with cephalometric parameters, with reliability highest for vertical dimensions and selected sagittal measures. Diagnostic accuracy ranged from fair to excellent. Transverse discrepancies were not assessed in any of the studies reviewed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Standardized facial photographs can serve as a valuable adjunct in orthodontic assessment, particularly for evaluating sagittal and vertical relationships. Although facial photographs demonstrate diagnostic utility, comprehensive assessment of skeletal discrepancies continues to rely on lateral cephalograms.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical significance: &lt;/strong&gt;Facial photography provides a practical, radiation-free tool that may enhance orthodontic diagnosis in selected contexts, especially when radiographic imaging is unavailable. Its greatest utility lies in sagittal and vertical assessment, while future integration with 3D photogrammetry and AI-based landmark detection may further improve diagnostic precision. How to cite this article: Novianty SI, Alhasyimi AA, Dewi AH, &lt;i&gt;et al.&lt;/i&gt; F","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 2","pages":"190-200"},"PeriodicalIF":0.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Nanosurface Evaluation and Antimicrobial Efficacy of Calcium Hydroxide-Coated Stainless Steel and Zirconia Crowns in Pediatric Dentistry: An Atomic Force Microscopic Study.","authors":"Somya Seth, Ramesh Ravikumar","doi":"10.5005/jp-journals-10024-4011","DOIUrl":"10.5005/jp-journals-10024-4011","url":null,"abstract":"<p><strong>Aim: </strong>To compare the nano-surface characteristics and antimicrobial efficacy of calcium hydroxide-coated stainless steel crowns (SSCs) and zirconia crowns using atomic force microscopy (AFM) and agar diffusion method.</p><p><strong>Materials and methods: </strong>An <i>in vitro</i> study was conducted using 10 crowns, divided into two groups: Five calcium hydroxide-coated zirconia crowns (Group I) and five calcium hydroxide-coated SSCs (Group II). Both crown types were uniformly coated with calcium hydroxide nanoparticles. Nanosurface topography was assessed using AFM, and antimicrobial activity against <i>Streptococcus mutans</i> and <i>Lactobacillus</i> species was evaluated using the agar well diffusion method. Antimicrobial plates were incubated for 24 hours before zone measurement. Data were analyzed using the Mann-Whitney <i>U</i> test, with <i>p</i> < 0.05 considered statistically significant.</p><p><strong>Results: </strong>Atomic force microscopy analysis revealed significantly higher nanoscale surface roughness in zirconia crowns compared to SSCs. Antimicrobial testing demonstrated markedly larger zones of inhibition for zirconia crowns against <i>S. mutans</i> and <i>Lactobacillus</i> compared to SSCs, statistically indicating highly significant differences.</p><p><strong>Conclusion: </strong>Calcium hydroxide-coated zirconia crowns exhibit superior nanoscale roughness and enhanced antimicrobial efficacy compared to calcium hydroxide coated stainless steel crowns.</p><p><strong>Clinical significance: </strong>This study addresses the clinical need for restorative options that not only restore form and function but also actively contribute to caries prevention in high-risk patients. Enhancing the antibacterial performance of preformed crowns through calcium hydroxide coatings may help limit bacterial colonization at crown margins, reduce the incidence of secondary caries, and support better longevity of both zirconia and SSCs. How to cite this article: Seth S, Ravikumar R. Comparison of Nanosurface Evaluation and Antimicrobial Efficacy of Calcium Hydroxide-Coated Stainless Steel and Zirconia Crowns in Pediatric Dentistry: An Atomic Force Microscopic Study. J Contemp Dent Pract 2026;27(1):37-43.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 1","pages":"37-43"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147445327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of Thalidomide for the Treatment of Minor Recurrent Aphthous Stomatitis: A Systematic Review.","authors":"Sulaiman S Alqahtani, Mohammed M Al Moaleem, Ibrahim Ma Qudhan, Hassan Hm Zakri, Ali Ma Tumayhi, Waleed My Moafa, Abdullah Aa Sahli, Abdullah S Sayd, Anas S Al-Zaghruri","doi":"10.5005/jp-journals-10024-3978","DOIUrl":"10.5005/jp-journals-10024-3978","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;This study presents a systematic review of the therapeutic potential and safety profile of thalidomide in managing minor recurrent aphthous stomatitis (RAS).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A PRISMA-guided systematic review was conducted using PubMed, Cochrane, ScienceDirect, Google Scholar, Semantic Scholar, and Wangfang. The search was performed from January 2014 to April 2025. Studies were selected based on the participants, intervention, control, and outcome (PICO) framework: (1) Population: Healthy individuals with minor RAS; (2) Intervention: Thalidomide; (3) Comparison: Placebo or standard therapy; (4) Outcomes: Recurrence interval, number of ulcers, healing time, pain intensity, complete and partial response rates, ulcer-free period, immunological parameters, and adverse effects.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Out of 1,600 initially retrieved records, 404 titles and abstracts were screened after removing duplicates, and 21 full texts were assessed. Five randomized clinical trials (RCTs) involving 607 participants met the eligibility criteria, which showed that thalidomide, especially at 25 mg/day for 8 weeks, significantly prolonged recurrence intervals and reduced ulcer count in patients with minor RAU. This regimen also resulted in the longest ulcer-free and relapse-free periods. Pain reduction and healing time improvement were inconsistent across studies. Some trials reported significant reductions in inflammatory markers (IL-6, TNF-α), especially with the 25 mg regimen. Combination therapy with multivitamins or glucosides of Paeony showed potential added benefits. Thalidomide was generally well tolerated, but mild side effects were more common compared to non-thalidomide treatments. Risk of bias was low for randomization but unclear or high in blinding and allocation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Thalidomide at a dose of 25 mg/day for 8 weeks appears effective in managing minor RAS by prolonging recurrence intervals and modulating anti-inflammatory markers. Its overall acceptable safety profile supports its consideration in selected patients; however, clinicians should remain vigilant for potential mild side effects.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical significance: &lt;/strong&gt;Thalidomide administered at 25 mg/day for 8 weeks demonstrates meaningful clinical benefits for patients with recurrent minor aphthous ulcers by notably prolonging remission intervals and lowering ulcer frequency and provides anti-inflammatory advantages, making it a valuable therapeutic option for patients who do not respond adequately to conventional treatments. While generally well tolerated, with mainly mild adverse effects, careful patient selection and monitoring remain essential to minimize risks and maximize therapeutic outcomes. How to cite this article: Alqahtani SS, Al Moaleem MM, Qudhan IMA, &lt;i&gt;et al&lt;/i&gt;. Efficacy and Safety of Thalidomide for the Treatment of Minor Recurrent Aphthous Stomatitis: A Systematic Review. J Contemp Dent P","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 1","pages":"83-91"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147445395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abnormal Tongue Behavior with Its Imaginable Influence on the Posterior Mandibular Dentoalveolar Structure.","authors":"Mustafa Mh Alsultan, Saba H Al Zubaidi, Niam R Alsaleem","doi":"10.5005/jp-journals-10024-4014","DOIUrl":"10.5005/jp-journals-10024-4014","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to evaluate the probable impression of the tongue forces on the posterior mandibular dentoalveolar structure through the assessment of the reflected stress distribution and the possible resultant displacement by finite element analysis on the mandibular model.</p><p><strong>Materials and methods: </strong>The AutoCAD (2010) software was used to design the three-dimensional mandibular study model for finite element analysis. A force of 2, 90, and 500 g/cm² that represents the forces expressed by the tongue during the normal rest posture, the normal function, and abnormal function, respectively, is applied perpendicularly to the lingual aspect of the mandibular model posterior portion.</p><p><strong>Results: </strong>Higher displacement values in the three axes of space <i>X</i>, <i>Y</i>, and <i>Z</i> are complementary to high von Mises stresses seen in abnormal tongue function state, and lowest for the normal rest posture, with normal function state in between.</p><p><strong>Conclusion: </strong>This study showed that abnormal lingual habits possibly have an adverse effect on the mandibular posterior structure. It may lead to abnormal deviation in the form and position during growth. How to cite this article: Alsultan MMH, Al Zubaidi SH, Alsaleem NR. Abnormal Tongue Behavior with Its Imaginable Influence on the Posterior Mandibular Dentoalveolar Structure. J Contemp Dent Pract 2026;27(1):27-32.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 1","pages":"27-32"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147445319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Efficacy of Smear Layer Removal Using Different Irrigation Activation Methods during Root Canal Treatment: An <i>In Vitro</i> Study.","authors":"K Geonath Immanuel, Preethi Anju, Sneha Sanap, Saicharan Gorre, Nada M Ibrahim, Mustafa H Alattas, Mazen F Alkahtany","doi":"10.5005/jp-journals-10024-4004","DOIUrl":"10.5005/jp-journals-10024-4004","url":null,"abstract":"<p><strong>Aim: </strong>The current investigation aimed to assess the effectiveness of smear layer removal during root canal therapy utilizing three different irrigation activation techniques.</p><p><strong>Materials and methods: </strong>The study included 60 human mandibular premolars that were recently extracted for orthodontic and periodontal reasons. The samples were decoronated with a diamond disc to provide a standard working length (WL) of 14 mm, and then the root canal preparation was completed. These samples were divided into three groups at random, each containing 20 samples (<i>n</i> = 20). Group I: Conventional needle irrigation; group II: Ultrasonic activation; and group III: EndoVac (EV) activation. The efficacy of smear layer removal in the coronal, middle, and apical thirds of all canals was assessed using a scanning electron microscope (SEM) with a magnification of 2,000×. Data were collected and analyzed statistically.</p><p><strong>Results: </strong>In the conventional needle irrigation group, the maximum smear layer removal was found in the middle third (0.72 ± 0.10), followed by the coronal third (0.80 ± 0.01) and the apical third (1.10 ± 0.14). No significant difference was found on intragroup comparison. In the irrigation with ultrasonic activation group, the maximum smear layer removal was found in the apical third (0.44 ± 0.02), followed by the middle third (0.48 ± 0.10) and the coronal third (0.64 ± 0.08). A significant difference was found on intragroup comparison. In the irrigation with EV activation group, the maximum smear layer removal was found in the apical third (0.20 ± 0.04), followed by the middle third (0.36 ± 0.18) and the coronal third (0.62 ± 0.04). A significant difference was found on intragroup comparison.</p><p><strong>Conclusion: </strong>The current investigation concluded that the EV system group removed more of the smear layer than the ultrasonic activation and conventional needle irrigation group.</p><p><strong>Clinical significance: </strong>The smear layer created during root canal instrumentation has a detrimental effect on root canal irrigation activity, which may have an impact on the endodontic treatment's prognosis. When an efficient irrigation delivery system is used, the irrigants can reach the WL. This kind of distribution method must have sufficient flow, be efficient in debriding the entire canal system, and supply an appropriate quantity of irrigants up to the WL. How to cite this article: Immanuel KG, Anju P, Sanap S, <i>et al</i>. Evaluation of the Efficacy of Smear Layer Removal Using Different Irrigation Activation Methods during Root Canal Treatment: An <i>In Vitro</i> Study. J Contemp Dent Pract 2026;27(1):55-58.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 1","pages":"55-58"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147444255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Effects of Micro-osteoperforation and Injectable Platelet-rich Fibrin on the External Root Resorption: A Split-mouth Prospective Study.","authors":"Priyanka Niranjane, Kushal P Taori, Krushnali Kolhatkar","doi":"10.5005/jp-journals-10024-4017","DOIUrl":"10.5005/jp-journals-10024-4017","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate and compare the effects of micro-osteoperforations (MOPs) and injectable platelet-rich fibrin (I-PRF) on external apical root resorption (EARR) during maxillary canine retraction using a split-mouth prospective study design.</p><p><strong>Materials and methods: </strong>Twenty orthodontic patients (mean age 22.8 ± 2.7 years) who required first premolar extractions bilaterally were recruited. In each subject, one quadrant was randomly assigned to MOP and the contralateral quadrant to I-PRF. All patients underwent fixed appliance therapy with a pre-adjusted edgewise system, and maxillary canines were retracted with NiTi closed-coil springs delivering 150 gm of force. Micro-osteoperforations were performed at the initiation of retraction, whereas I-PRF was injected monthly. To measure changes in root length, cone-beam computed tomography (CBCT) images of the patients were taken both prior to and following full canine retraction (T0 and T1, respectively). Statistical analysis was completed using unpaired and paired <i>t</i>-tests (<i>p</i> < 0.05).</p><p><strong>Results: </strong>Both groups demonstrated significant root length reduction after retraction (<i>p</i> < 0.05). The mean EARR in the MOP group was 1.21 ± 0.25 mm, while the I-PRF group showed 1.00 ± 0.10 mm of resorption. Despite the MOP group's somewhat higher resorption, there were no clinically noteworthy distinctions between the two categories (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>Micro-osteoperforations and I-PRF are both effective adjuncts for facilitating orthodontic tooth movement (OTM); however, both approaches are associated with measurable root resorption. There is no statistically significant difference observed between the two techniques in terms of minimizing EARR.</p><p><strong>Clinical significance: </strong>While MOPs and I-PRF can shorten treatment duration, clinicians should remain cautious of their potential to induce root resorption. Injectable PRF may offer additional biological benefits owing to its regenerative properties, but long-term studies with larger samples should be done before definitive clinical recommendations are suggested. How to cite this article: Niranjane P, Taori KP, Kolhatkar K. Evaluation of the Effects of Micro-osteoperforation and Injectable Platelet-rich Fibrin on the External Root Resorption: A Split-mouth Prospective Study. J Contemp Dent Pract 2026;27(1):78-82.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"27 1","pages":"78-82"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147445363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}