Journal of Contemporary Dental Practice最新文献

{"title":"Inheritance of Class III Soft Tissue Facial Features from Parents to Offsprings Using Photogrammetric Analysis Technique.","authors":"Faisal Arshad, C S Prashanth, H C ShashiKumar, B C Amarnath, G S Shwetha, N K Lokesh","doi":"10.5005/jp-journals-10024-3731","DOIUrl":"10.5005/jp-journals-10024-3731","url":null,"abstract":"<p><strong>Aim: </strong>The present study was undertaken to analyze the facial features in class III patients by measuring the facial frontal (linear) parameters and profile (angular) parameters and correlate them with parents to determine the inheritance of facial features.</p><p><strong>Materials and methods: </strong>The sample consisted of 40 class III patients aged between 9 and 18 years based on skeletal ANB angle (less than 0 degrees) and Angle's class III classification. Frontal and profile photographs of the subjects and parents were taken in a standardized position according to ABO guidelines. The photographs were analyzed using custom-made software for measuring various frontal (linear) and profile (angular) parameters to check for the degree of resemblance of facial features with parents by determining mean value, standard deviation and by applying Student's <i>t</i>-test. The level of significance was set at 5% (<i>p</i> < 0.05).</p><p><strong>Results: </strong>The common facial frontal (linear) parameters in sons and daughters which showed close mean inheritance (<i>p</i> < 0.005) with father were: 1. Al-Me/Ex-Al(R), 2. Al-Me/Ex-Al (L), 3. Al-Me/Ch-Me(R), 4. Al-Me/Ch-Me (L), 5. Ch-Me/Al-Ch(R), and 6. Ch-Me/Al-Ch(L). The common facial profile (angular) parameters in sons and daughters which showed close mean inheritance (<i>p</i> < 0.005) with mother were: 1. nasolabial angle (Cm-Sn-Ls), 2. nasofacial angle (G-Pog/N-Nd), 3. total convexity except nose (G-Sn-Pog), 4. upper lip projection angle (N-Pog/N-Ls), 5. lower lip projection angle (N-Pog/N-Li), and 6. Sn-Po-Gn. The only linear parameter which showed close mean inheritance with mother in both sons and daughters was: 1. ChR-ChL/AIR-AIL (<i>p</i> = 0.0001).</p><p><strong>Conclusion: </strong>Facial frontal (linear) parameters showed close inheritance with father in sons and daughters, while profile (angular) parameters showed close inheritance with mother in sons and daughters. The linear vertical parameters have more inheritance in daughters than sons, while angular parameters have more inheritance in sons as compared to daughters. Overall, facial inheritance from father is more dominant in class III sons and daughters.</p><p><strong>Clinical significance: </strong>The results of this study simplify the orthodontic treatment planning in subjects having class III malocclusion in terms of predicting the course of facial growth from parents. Such prediction can guide in forecasting the treatment outcome in complex malocclusion like class III. The results of this study revealed various parameters which are less heritable, having lesser genetic component, and mostly influenced by environment which can be modified through orthodontics and Dentofacial Orthopedics, thereby having lesser chances of relapse. The results of this study can also be utilized in the field of plastic surgery and forensic science. How to cite this article: Arshad F, Prashanth CS, ShashiKumar HC, <i>et al</i>. Inh","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 12","pages":"1162-1171"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative Evaluation of Nerve Function Following Coronal Incisions for Facial Fractures: A Clinical Study.","authors":"Anwesha Pattnayak, Naman Awasthi, Narendra V Penumatsa, Prasanth Panicker, Sohail Ferdous, Mukesh Soni","doi":"10.5005/jp-journals-10024-3743","DOIUrl":"10.5005/jp-journals-10024-3743","url":null,"abstract":"<p><strong>Aim: </strong>The present study aimed to evaluate the postoperative nerve function following coronal incisions for facial fractures.</p><p><strong>Materials and methods: </strong>The present study included 30 patients with craniomaxillofacial trauma treated using the bi-temporal/coronal or hemicoronal approach. A preoperative computed tomography (CT) scan of the face with 3D reconstruction was done for all the patients to determine the exact extent of the fractures. All the cases were undertaken with general anesthesia and endotracheal intubation. Under all aseptic conditions, a coronal incision was given, reflection of the flap was done and fracture segments were approached. Reduction and fixation were achieved at the sites and closure was done. Postoperatively, neurological deficits in the zygomaticotemporal, supraorbital, and frontal branches of the facial nerve were closely observed at 1-, 4-, 16-, 24-, and 52-weeks intervals.</p><p><strong>Results: </strong>In all 30 patients, the duration of recovery varied between 16 weeks, 24 weeks, 32 weeks and 52 weeks but at the end of 32-52 weeks all the deficits subsided. There was a marked recovery between 16 and 24 weeks, with a complete resolution of 52 weeks. The study found a significant association between recovery time and nerve healing, highlighting the coronal approach's effectiveness in treating complex facial fractures while preserving nerve integrity.</p><p><strong>Conclusion: </strong>In conclusion, the study found that while patients undergoing craniomaxillofacial reconstruction via the coronal approach initially experienced notable neurological deficits, full nerve function was ultimately restored over time, underscoring a strong correlation between nerve healing and favorable functional outcomes.</p><p><strong>Clinical significance: </strong>The coronal approach not only delivers superior esthetic results but also safeguards neural integrity, minimizing the risk of nerve impairment often associated with traditional methods of fracture management. Coronal incisions provide superior access for precise anatomic reduction and preserve nerve integrity. How to cite this article: Pattnayak A, Awasthi N, Penumatsa NV, <i>et al</i>. Postoperative Evaluation of Nerve Function Following Coronal Incisions for Facial Fractures: A Clinical Study. J Contemp Dent Pract 2024;25(12):1135-1140.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 12","pages":"1135-1140"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Vitamin D3 on Postorthodontic Treatment Stability: A Randomized Controlled Trial.","authors":"Thrivikhraman Kothandaraman, Prema Anbarasu, Sp Saravana Dinesh, Saravana Kumar Subramanian, Gabriel Eisenhuth, Sebastian Eisenhuth, Claudia Eisenhuth","doi":"10.5005/jp-journals-10024-3795","DOIUrl":"10.5005/jp-journals-10024-3795","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to clinically evaluate whether the local administration of vitamin D3 enhances postorthodontic tooth stability over a period of 3 months immediately after debonding.</p><p><strong>Materials and methods: </strong>Patients aged 15-30 years with dental malocclusion and moderate crowding in the lower arch (Little's irregularity score of 4-6) were selected and randomly split into the experimental and the control groups. After complete alignment and leveling, vitamin D3 injection was delivered to the experimental group and the control group was given a placebo injection with 0.9% normal saline mixed with 2% lignocaine. Fourteen days after the injection, the lower archwires were removed from the control and experimental groups.</p><p><strong>Results: </strong>Relapse was significantly higher in control than in the experimental group at all-time intervals. Statistically significant values of relapse were observed at T2 and T3 intervals between the two groups, with greater relapse in the control group than in the experimental group. Inter-canine width, arch perimeter, and intermolar width showed mild changes over 3-month period, but there were no significant differences between the two groups.</p><p><strong>Conclusion: </strong>Relapse was seen in both the control and the experimental in the first 4 weeks of the study. Still, the control group showed a greater relapse rate in the following 8th week and 12th week when compared to the experimental group. How to cite this article: Kothandaraman T, Anbarasu P, Dinesh SPS, <i>et al</i>. Impact of Vitamin D3 on Postorthodontic Treatment Stability: A Randomized Controlled Trial. J Contemp Dent Pract 2024;25(12):1156-1161.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 12","pages":"1156-1161"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Obstructive Sleep Apnea on Masticatory Muscle Function.","authors":"Diana Russo, Luis Eduardo Almeida, Vincenzo Ronsivalle, Marco Cicciù, Gabriele Cervino, Maria Maddalena Marrapodi, Giuseppe Minervini","doi":"10.5005/jp-journals-10024-3783","DOIUrl":"10.5005/jp-journals-10024-3783","url":null,"abstract":"<p><p>How to cite this article: Russo D, Almeida LE, Ronsivalle V, <i>et al.</i> Impact of Obstructive Sleep Apnea on Masticatory Muscle Function. J Contemp Dent Pract 2024;25(11):997-1000. Keywords: Apnea-hypopnea index, Diabetes, Obstructive sleep apnea, Temporomandibular joint.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"997-1000"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Evaluation of Osseodensification vs Conventional Osteotomy Technique on Primary and Secondary Implant Stability in Rabbit Model Split Body RCT.","authors":"Sudhakar Arpudaswamy, S Syed A Ali, Suma Karthigeyan, Ponnanna A Appanna, K Vinod Kumar, Rohit M Shetty","doi":"10.5005/jp-journals-10024-3751","DOIUrl":"10.5005/jp-journals-10024-3751","url":null,"abstract":"<p><strong>Aim and objective: </strong>To measure and contrast primary stability metrics, such as insertion torque values and implant stability quotient (IQS) at the time of implant placement, and secondary stability metrics, such as ISQ three months post-implant insertion, between implants inserted in osteotomy sites prepared with conventional drills and osseodensification drills (OD) in the femoral condyles of female New Zealand white rabbits, which are characterized by low-density D4 type bone.</p><p><strong>Materials and methods: </strong>Eight female New Zealand white strain rabbits, each 14 weeks old and weighing approximately 2.5 ± 0.3 kg, were utilized for this study. Using aseptic techniques and local anesthesia, a 3.1 × 8 mm implant was inserted into the rabbit's left femoral condyle using conventional drills (group I) from the Zimmer surgical kit. Similarly, using Densah drills (group II), a 3.1 mm × 8 mm implant was inserted into the rabbit's right femoral condyle. Primary implant stability was evaluated using insertional torque and ISQ values during insertion of implants using a torque wrench and radiofrequency analyzer, respectively. Secondary implant stability was evaluated by measuring ISQ values three months after implant placement.</p><p><strong>Results: </strong>Group I had a mean insertional torque of 31.13 ± 1.727 Ncm, while group II had 33.00 ± 1.309 Ncm. ISQ during insertion was 63.63 ± 5.927 in group I and 63.62 ± 7.615 in group II. After three months, ISQ was 67.25 ± 6.45 in group II and 75 ± 6.85 in group II. Significant differences were found in insertional torque (<i>p</i> = 0.028), ISQ after three months (<i>p</i> = 0.0353), and ISQ changes over time (<i>p</i> = 0.001), but not in ISQ at the time of implant placement.</p><p><strong>Conclusion: </strong>The investigation demonstrated that implants placed using the OD exhibited superior initial stability and subsequent stability progression compared to those placed using conventional drilling techniques in a rabbit model.</p><p><strong>Clinical significance: </strong>Primary and secondary implant stability are critical factors for successful implant treatment in clinical practice. Osseodensification demonstrates a higher insertional torque and implant stability quotient by enhancing bone density and volume surrounding implants. This enhanced stability can lead to improved osseointegration and reduced healing times, ultimately benefiting patients with compromised bone quality. How to cite this article: Arpudaswamy S, Ali SSA, Karthigeyan S, <i>et al.</i> Comparative Evaluation of Osseodensification vs Conventional Osteotomy Technique on Primary and Secondary Implant Stability in Rabbit Model Split Body RCT. J Contemp Dent Pract 2024;25(11):1052-1059.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"1052-1059"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physicochemical Properties and Bacterial Adhesion of Conventional and 3D Printed Complete Denture PMMA Materials: An <i>In Vitro</i> Study - Part I.","authors":"Pierre Khoury, Naji Kharouf, Olivier Etienne, Jean-Philippe Dillenseger, Youssef Haikel, Hatem M El-Damanhoury, Dani Irani, Mutlu Ozcan, Ziad Salameh","doi":"10.5005/jp-journals-10024-3781","DOIUrl":"10.5005/jp-journals-10024-3781","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate and compare the surface morphology, wettability, roughness, and bacterial adhesion properties of polymethyl methacrylate (PMMA) materials fabricated by conventional methods and 3D printing for complete denture applications.</p><p><strong>Materials and methods: </strong>Two PMMA materials were investigated: Conventionally processed (ProBase Hot) and 3D-printed (3DP) (V-Print Dentbase). Surface morphology (<i>n</i> = 3) was analyzed using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). Surface roughness (<i>n</i> = 10) was measured using an optical profilometer. Wettability was assessed through contact angle measurements (<i>n</i> = 6) at 10, 30, and 60 seconds. Bacterial adhesion (<i>n</i> = 9) and biofilm formation (<i>n</i> = 3) were evaluated using <i>Escherichia coli</i> (<i>E. coli</i>) as a model organism, with quantitative bacterial counts and SEM analysis of bacterial morphology. Data were statistically analyzed.</p><p><strong>Results: </strong>Scanning electron microscopy analysis revealed nanoparticles on the surface of 3DP samples, while EDX detected silicon in these samples, absent in conventional PMMA. 3D-printed surfaces exhibited significantly lower roughness (1.05 ± 0.32 µm) compared to conventional surfaces (20.46 ± 6.71 µm) (<i>p</i> < 0.001). Contact angle measurements showed that 3DP surfaces were more hydrophilic (64-68°) than conventional surfaces (100°) (<i>p</i> < 0.05). Bacterial adhesion studies demonstrated more adherent bacteria on 3DP surfaces (92.5 ± 30.8) compared to the conventional surfaces (57.6 ± 12.5), but biofilm formation was observed only on conventional surfaces.</p><p><strong>Conclusion: </strong>3D-printed PMMA exhibited distinct surface characteristics compared to conventionally processed PMMA, including the presence of silicon nanoparticles, lower surface roughness, and higher hydrophilicity. While 3DP surfaces showed higher initial bacterial adherence, in contrast, they appeared to inhibit biofilm formation, which highlights the complex nature of bacterial interactions with these materials.</p><p><strong>Clinical significance: </strong>Further clinical studies are needed to validate the results of this investigation and generate clinical translational data. How to cite this article: Khoury P, Kharouf N, Etienne O, <i>et al.</i> Physicochemical Properties and Bacterial Adhesion of Conventional and 3D Printed Complete Denture PMMA Materials: An <i>In Vitro</i> Study - Part I. J Contemp Dent Pract 2024;25(11):1001-1008.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"1001-1008"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>In Vitro</i> Comparison of Color Matching: Universal Shade Composite Resin vs Multi-shade Conventional Composite.","authors":"Walaa F Bisharah, Ahmed S Zahran, Mona T Rajeh, Nada A AbdelAleem","doi":"10.5005/jp-journals-10024-3780","DOIUrl":"10.5005/jp-journals-10024-3780","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to evaluate and compare the color matching of OMNICHROMA (OM), a universal shade composite, to the well-established 3M Filtek Z350 composites (FT).</p><p><strong>Materials and methods: </strong>An <i>in vitro</i> experimental study was conducted on 80 freshly extracted permanent teeth, with intact buccal surfaces. The teeth were randomly assigned to four groups: Group I OM and groups II, III, and IV (3M Filtek Z350 in shades A3, A3.5, and B2, respectively). Class V cavity preparations were created and restored using the respective composites. Color matching was assessed instrumentally using a spectrophotometer to calculate the color difference (Δ<i>E</i>) values and visually by three trained observers using a standardized visual scoring system.</p><p><strong>Results: </strong>Visual assessments showed no significant differences in color matching across the four groups. However, the Δ<i>E</i> color matching analysis revealed significant differences (<i>p</i> < 0.0001), with OM exhibiting higher Δ<i>E</i> values compared to FT shades A3.5 and B2. No significant difference was found between OM and shade A3.</p><p><strong>Conclusion: </strong>OMNICHROMA demonstrated excellent visual color matching, comparable to the various shades of FT composites. Despite the higher Δ<i>E</i> values observed instrumentally in comparison to shades A3.5 and B2, OM's ability to blend with different tooth shades visually was highly effective.</p><p><strong>Clinical significance: </strong>These results suggest that OM offers a versatile and reliable option for achieving satisfactory esthetic outcomes, reducing the need for multiple shade variations in restorative procedures. How to cite this article: Bisharah WF, Zahran AS, Rajeh MT, <i>et al.</i> <i>In Vitro</i> Comparison of Color Matching: Universal Shade Composite Resin vs Multi-shade Conventional Composite. J Contemp Dent Pract 2024;25(11):1039-1044.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"1039-1044"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An <i>Ex-vivo</i> Evaluation of Sealability of Three Bioceramic Physical Variants in Coronal and Apical Thirds of Root Canals.","authors":"Murali H Rao, Rajkumar Krishnan, Pavithra Gopal, Elizabeth Thomas","doi":"10.5005/jp-journals-10024-3770","DOIUrl":"10.5005/jp-journals-10024-3770","url":null,"abstract":"<p><strong>Aim: </strong>To assess the coronal and apical microleakage of mineral trioxide aggregate (MTA), Biodentine, and Bioceramic putty when used as coronal and apical seals in endodontically treated teeth.</p><p><strong>Materials and methods: </strong>The study was conducted on 90 mandibular premolar teeth. The groups were divided into two subgroups. One group assessed the coronal seal (<i>n</i> = 45), and the other group assessed the apical seal (<i>n</i> = 45). Coronal and apical 3 mm of the root filling was removed and replaced randomly with MTA, Biodentine, and Bioceramic putty in the three experimental subgroups (<i>n</i> = 15). All teeth were immersed in methylene blue and after incubation, the degree of dye penetration was assessed under a stereomicroscope of ×10 magnification. Statistical analysis was done using the Kruskal-Wallis test with a <i>p</i>-value set at 0.05.</p><p><strong>Results: </strong>The mean depth of dye penetration for coronal sealing in the MTA group was 2.91 ± 0.66, in the Biodentine group was 2.12 ± 0.50 and in the Bioceramic putty group was 1.51 ± 0.46. The mean depth of dye penetration for root-end sealing in the MTA group was 0.75 ± 0.55, in the Biodentine group was 1.94 ± 0.88 and in the Bioceramic putty group was 0.29 ± 0.20.</p><p><strong>Conclusion: </strong>Within the limitations of this study, it can be concluded that Bioceramic putty exhibited better sealing ability in both coronal and apical barriers of root canals.</p><p><strong>Clinical significance: </strong>The sealing ability of a material vastly influences the treatment outcome of nonsurgical and surgical root therapy. The study evaluates the coronal and apical seal of three physical variants of Bioceramic material. How to cite this article: Rao MH, Krishnan R, Gopal P, <i>et al.</i> An <i>Ex-vivo</i> Evaluation of Sealability of Three Bioceramic Physical Variants in Coronal and Apical Thirds of Root Canals. J Contemp Dent Pract 2024;25(11):1022-1026.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"1022-1026"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Serum Calcium and Vitamin D Levels in Patients with and without Periodontitis before and after Nonsurgical Periodontal Therapy.","authors":"Srishti Wadhwa, Kumar Saurav, Sachit A Arora, Rupali Kalsi, Gunjan Gupta, Shivesh Mishra, Ritika Gupta","doi":"10.5005/jp-journals-10024-3775","DOIUrl":"10.5005/jp-journals-10024-3775","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate and correlate levels of serum calcium and 25-hydroxycholecalciferol (vitamin D) in subjects with periodontitis and in subjects with healthy periodontium before and following nonsurgical periodontal therapy (NSPT).</p><p><strong>Materials and methods: </strong>A total of 52 patients were enrolled in the study with 26 patients in each group. The control group included patients without periodontitis, whereas the study group included patients with periodontitis. On the first visit, ~ 3-5 mL of venous blood was collected from all the participants for the assessment of calcium and Vitamin D levels in the blood. The various parameters evaluated included probing depth, clinical attachment level (CAL), gingival index (Loe and Silness 1963). Plaque index (Silness and Loe 1964), and IOPA (site having greatest pocket depth). Participants of both the groups received NSPT which involved extensive scaling and root planing. On the second visit (after 3 months), the same clinical parameters except IOPA were recorded in all the participants. On the third visit (after 6 months from the first visit), the blood sample was again collected for the evaluation of serum calcium and Vitamin D, and all the parameters of baseline were recorded.</p><p><strong>Result: </strong>The result of the study showed that Vitamin D levels at baseline were less in test subjects (12.73 ± 2.25) as compared to controls (17.81 ± 4.03), which improved at 6 months for the test group (24.53 ± 1.98) but not the control group (17.8 ± 4.14) following NSPT. All the clinical parameters improved for both groups. There was no statistically significant difference in the calcium levels of both groups at baseline or 6 months.</p><p><strong>Conclusion: </strong>Vitamin D levels were found to be lower in periodontitis patients than healthy controls, vitamin D levels improved in the test subjects along with the clinical parameters following NSPT highlighting the beneficial role of Vitamin D in maintaining periodontal health. No changes were seen in calcium levels in either of the groups at any point in time.</p><p><strong>Clinical significance: </strong>Vitamin D can reduce the incidence and severity of periodontal disease by its various anti-inflammatory and immunomodulatory effects in addition to its traditional role in bone metabolism. Thus, maintaining adequate levels of systemic vitamin D could be critical to periodontal health. This study justifies this notion and further suggests the adjunctive role of vitamin D supplementation to improve therapeutic outcomes. How to cite this article: Wadhwa S, Saurav K, Arora SA, <i>et al.</i> Correlation of Serum Calcium and Vitamin D Levels in Patients with and without Periodontitis before and after Nonsurgical Periodontal Therapy. J Contemp Dent Pract 2024;25(11):1034-1038.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"1034-1038"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Glucose-6-Phosphate dehydrogenase in Saliva of Subjects with Normal Appearing Gingiva and Periodontitis using qRT-PCR: A Cross-sectional Study.","authors":"Ninad V Chavan, Sahana Srinath, Satish Thimmaiah Yadava, Savita Shiragur, Akalya Purushothaman, Hajira Khatoon, Vaishnavi Setloor","doi":"10.5005/jp-journals-10024-3772","DOIUrl":"10.5005/jp-journals-10024-3772","url":null,"abstract":"<p><strong>Aims: </strong>To determine the salivary level of glucose-6-phosphate dehydrogenase (G6PD) in subjects with normal appearing gingiva and periodontitis, and to compare the salivary levels of G6PD in all the study groups.</p><p><strong>Materials and methods: </strong>Unstimulated saliva (4 mL) was collected from 30 subjects; 15 periodontitis subjects and 15 control subjects. Later, saliva samples were subjected to RNA extraction via TRIzol method. The RNA was converted to complementary DNA, and quantitative real time polymerase chain reaction was set-up.</p><p><strong>Results: </strong>The expression of salivary G6PD in periodontitis subjects showed a significant increase when compared with control subjects, with a <i>p</i>-value of 0.001 (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>In conclusion, the overall results show promise in future aspects of G6PD as a potential diagnostic as well as a prognostic marker. However, large-scale, multi-institutional, and large sample sized studies should be conducted to further find out the importance of G6PD in the diagnosis of periodontitis and its prognostic value.</p><p><strong>Clinical significance: </strong>The increase of G6PD levels in periodontitis subjects shows the increased oxidative stress, and this can be used for developing new noninvasive diagnostic procedures, developing novel treatment modalities, and also in assessing prognosis of treated cases of periodontitis. How to cite this article: Chavan NV, Srinath S, Yadava ST, <i>et al.</i> Evaluation of Glucose-6-Phosphate dehydrogenase in Saliva of Subjects with Normal Appearing Gingiva and Periodontitis using qRT-PCR: A Cross-sectional Study. J Contemp Dent Pract 2024;25(11):1060-1068.</p>","PeriodicalId":35792,"journal":{"name":"Journal of Contemporary Dental Practice","volume":"25 11","pages":"1060-1068"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}