Current Research in Microbial Sciences最新文献

{"title":"Low leucocyte, neutrophil and lymphocyte count (tri-low phenotype) in melioidosis: A predictor of early mortality","authors":"Nitin Gupta ,&nbsp;Praveen Kumar Tirlangi ,&nbsp;Prithvishree Ravindra ,&nbsp;Rachana Bhat ,&nbsp;Mukund Gupta ,&nbsp;Carl Boodman ,&nbsp;Adil Rashid ,&nbsp;Chiranjay Mukhopadhyay","doi":"10.1016/j.crmicr.2024.100303","DOIUrl":"10.1016/j.crmicr.2024.100303","url":null,"abstract":"<div><h3>Introduction</h3><div>Melioidosis is a bacterial disease caused by <em>Burkholderia pseudomallei</em>, a gram-negative bacillus endemic to parts of Asia and Northern Australia<strong>.</strong> This study aimed to identify the role of total and differential leucocyte count in predicting 48-h mortality in patients with melioidosis.</div></div><div><h3>Methodology</h3><div>This retrospective cohort study included patients diagnosed with culture-proven melioidosis at Kasturba Medical College between 2017 and 2023. Total leucocyte count (TLC), absolute neutrophil count (ANC), and absolute lymphocytic count (ALC) were classified into low (first quartile), medium (second and third quartile) and high (last quartile). The chi-square test was used to compare each group's early (48-h) mortality.</div></div><div><h3>Results</h3><div>Of the 170 patients with culture-confirmed melioidosis, 24 patients died within 48 h. The mortality was significantly higher in those with low TLC, ANC and ALC. When all three parameters were found to be low (tri-low phenotype), the specificity in predicting mortality was 93.2 %.</div></div><div><h3>Conclusion</h3><div>Low TLC, ANC and ALC are significant predictors of mortality among melioidosis patients. There is a need to explore new strategies to improve clinical outcomes among melioidosis patients with tri-low phenotype.</div></div>","PeriodicalId":34305,"journal":{"name":"Current Research in Microbial Sciences","volume":"7 ","pages":"Article 100303"},"PeriodicalIF":4.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142661835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Degradation of lignocellulose by different bacterial and fungal co-cultures","authors":"Julian Detain,&nbsp;Ludovic Besaury","doi":"10.1016/j.crmicr.2024.100271","DOIUrl":"10.1016/j.crmicr.2024.100271","url":null,"abstract":"<div><p>Long seen as non-valorisable waste, agricultural co-products are increasingly used in biorefinery processes. Co-culture appears as new trend for to improve the degradation of lignocellulose and improve the production of bioproducts. The goal of the study was to setup inter-domain co-cultures with high capabilities of lignocellulose degradation using a pluridisciplinary approach combining bioinformatics, enzymology, transcriptomics. Different individual lignocellulolytic strains: <em>Trichoderma reesei</em> QM6a and three bacteria (<em>Streptomyces coelicolor</em> A3(2), <em>Rhizobium</em> sp.XylPr11 and <em>Sphingobacterium prati</em> AraPr2 affiliated from different phyla) were used in that study . Synergic activities have been observed and quantified in co-culture conditions, particularly for xylanases and peroxidases activities. The enzymatic activities for the co-cultures in the most interesting co-culture (<em>T. reesei QM6a/S. coelicolor A3(2)</em>) reached more up to 2 IU/mL and 430 IU/mL respectively for the xylanase and peroxidase. Furthermore, ATR-FTIR analysis showed a real impact of co-culture condition on the substrate compared to the monoculture specially for hemicellulose degradation. Transcriptomics of <em>S. coelicolor</em> A3(2) either in mono or co-culture showed a relative similar pattern profile whatever the condition analysed with a specific overexpression of certain CAZyme genes involved in glycolysis due to the hydrolytic role played by the fungal partner. This work provided the proof of concept for technological feasibility, pertinence and usefulness of interdomain co-culture.</p></div>","PeriodicalId":34305,"journal":{"name":"Current Research in Microbial Sciences","volume":"7 ","pages":"Article 100271"},"PeriodicalIF":4.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666517424000531/pdfft?md5=3affb225bcb8fb63efcf3efe4560a02c&pid=1-s2.0-S2666517424000531-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142148033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The green shield: Trichoderma's role in sustainable agriculture against soil-borne fungal threats","authors":"Mansoor Ahmad Malik,&nbsp;Nusrat Ahmad,&nbsp;Mohd Yaqub Bhat","doi":"10.1016/j.crmicr.2024.100313","DOIUrl":"10.1016/j.crmicr.2024.100313","url":null,"abstract":"<div><div>Soil-borne pathogenic fungi are a major agricultural concern, leading to significant decreases in plant yield. Chemically controlling these plants imposes environmental threats that could potentially endanger both humans and other animals. Therefore, employing biological methods in plant disease control represents a more effective alternative approach. The objective of this study was to isolate <em>Trichoderma</em> species from soil samples and evaluate their in vitro biocontrol efficacy against fungal pathogens viz. <em>Fusarium oxysporum, Aspergillus niger, Rhizoctonia solani, Cladosporium cladosporioides, Alternaria alternata, Penicillium citrinum, Curvularia lunata, Fusarium metavorans, Aspergillus flavus, Penicillium chrysogenum, Nigrospora sphaerica,</em> and <em>Fusarium solani.</em> The biocontrol testing efficacy of the isolates against various fungal pathogens was assessed using the dual culture technique<em>.</em> In this investigation various <em>Trichoderma</em> species were isolated from 25 soil samples and were tested against 12 soil borne fungal pathogens. The radial growth inhibition of <em>Trichoderma harzanium</em> and <em>Trichoderma viride</em> varied between (20.18% to 58.13% t), (07.01% to 67.16%) respectively. Furthermore, the culture filtrates of <em>Trichoderma</em> species at different concentrations (5%, 10%, 15%, and 20%) caused a significant reduction in the mycelial growth of all the tested fungal pathogens<em>.</em> The radial growth inhibition was more by higher concentrations in comparison to low concentrations. In the light of these observations, native <em>Trichoderma</em> species seems to be competent biocontrol agents and provide as a sustainable method against disease caused by soil borne plant pathogens.</div></div>","PeriodicalId":34305,"journal":{"name":"Current Research in Microbial Sciences","volume":"7 ","pages":"Article 100313"},"PeriodicalIF":4.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142702569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbial biosurfactants: Green alternatives and sustainable solution for augmenting pesticide remediation and management of organic waste","authors":"Shiv Shankar Markam ,&nbsp;Aman Raj ,&nbsp;Ashwani Kumar ,&nbsp;Mohammed Latif Khan","doi":"10.1016/j.crmicr.2024.100266","DOIUrl":"10.1016/j.crmicr.2024.100266","url":null,"abstract":"<div><p>Pesticide pollution remains a significant environmental challenge, necessitating the exploration of sustainable alternatives. Biosurfactants are a class of unconventional surface-active chemicals that are produced by microorganisms. Biosurfactants have many applications in treating oil spills, emulsifiers, pharmaceuticals, and agriculture. Compared to chemical surfactants, they have benefits such as biodegradability, less toxicity, and a greener option because they are derived from microbes. Biosurfactants have recently been shown to have the potential to speed up pesticide cleanup. Biosurfactants are used in pesticide remediation because of their exceptional foaming ability, high selectivity, and wide range of pH, salinity, and temperature operating windows. Microbial biosurfactants emerged as potential agents for the treatment of organic waste and agricultural residue. This review unfolds the promising realm of microbial biosurfactants as green solutions for environmental sustainability, particularly in agricultural practices, with special reference to pesticide remediation. This article highlights the escalating need for eco-friendly alternatives, paving the way for discussing biosurfactants. Moreover, the articles discuss in detail various advancements in the field of rapid screening of biosurfactants, either using a conventional approach or <em>via</em> advanced instruments such as GC-MS, HPLC, NMR, FTIR, etc. Furthermore, the article unveils the molecular mechanisms and the microbial genes driving biosurfactant synthesis, offering insights into enhancing production efficiency. Moreover, the article explores diverse applications of microbial biosurfactants in sustainable agriculture, ranging from soil remediation to crop protection. The article also highlights the various functions of microbial biosurfactants for enhancing the decomposition and recycling of organic waste and agricultural residues, emphasizing their potential for sustainable waste management strategies. Overall, the review underscores the pivotal role of microbial biosurfactants as green alternatives for addressing pesticide pollution and advancing environmental sustainability.</p></div>","PeriodicalId":34305,"journal":{"name":"Current Research in Microbial Sciences","volume":"7 ","pages":"Article 100266"},"PeriodicalIF":4.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666517424000488/pdfft?md5=10f93e26d3aee6b7cb0b6a955ff7cd69&pid=1-s2.0-S2666517424000488-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142044642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct and indirect technical guide for the early detection and management of fungal plant diseases","authors":"Gargi Sharma ,&nbsp;Vagish Dwibedi ,&nbsp;Chandra Shekhar Seth ,&nbsp;Simranjeet Singh ,&nbsp;Praveen C Ramamurthy ,&nbsp;Pooja Bhadrecha ,&nbsp;Joginder Singh","doi":"10.1016/j.crmicr.2024.100276","DOIUrl":"10.1016/j.crmicr.2024.100276","url":null,"abstract":"<div><div>Fungal plant diseases are a major threat to plants and vegetation worldwide. Recent technological advancements in biotechnological tools and techniques have made it possible to identify and manage fungal plant diseases at an early stage. These techniques include direct methods, such as ELISA, immunofluorescence, PCR, flow cytometry, and in-situ hybridization, as well as indirect methods, such as fluorescence imaging, hyperspectral techniques, thermography, biosensors, nanotechnology, and nano-enthused biosensors. Early detection of fungal plant diseases can help to prevent major losses to plantations. This is because early detection allows for the implementation of control measures, such as the use of fungicides or resistant varieties. Early detection can also help to minimize the spread of the disease to other plants. The techniques discussed in this review provide a valuable resource for researchers and farmers who are working to prevent and manage fungal plant diseases. These techniques can help to ensure food security and protect our valuable plant resources.</div></div>","PeriodicalId":34305,"journal":{"name":"Current Research in Microbial Sciences","volume":"7 ","pages":"Article 100276"},"PeriodicalIF":4.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666517424000580/pdfft?md5=ec54527c22826ddf0eeb5c756cfcc320&pid=1-s2.0-S2666517424000580-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142312754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strigolactone GR24-mediated mitigation of phosphorus deficiency through mycorrhization in aerobic rice","authors":"Debasis Mitra ,&nbsp;Periyasamy Panneerselvam ,&nbsp;Parameswaran Chidambaranathan ,&nbsp;Amaresh Kumar Nayak ,&nbsp;Ankita Priyadarshini ,&nbsp;Ansuman Senapati ,&nbsp;Pradeep Kumar Das Mohapatra","doi":"10.1016/j.crmicr.2024.100229","DOIUrl":"https://doi.org/10.1016/j.crmicr.2024.100229","url":null,"abstract":"<div><p>Strigolactones (SLs) are a new class of plant hormones that play a significant role in regulating various aspects of plant growth promotion, stress tolerance and influence the rhizospheric microbiome. GR24 is a synthetic SL analog used in scientific research to understand the effects of SL on plants and to act as a plant growth promoter. This study aimed to conduct hormonal seed priming at different concentrations of GR24 (0.1, 0.5, 1.0, 5.0 and 10.0 µM with and without arbuscular mycorrhizal fungi (AMF) inoculation in selected aerobic rice varieties (CR Dhan 201, CR Dhan 204, CR Dhan 205, and CR Dhan 207), Kasalath-IC459373 (P-tolerant check), and IR-36 (P-susceptible check) under phosphorus (P)-deficient conditions to understand the enhancement of growth and priming effects in mycorrhization. Our findings showed that seed priming with 5.0 µM SL GR24 enhanced the performance of mycorrhization in CR Dhan 205 (88.91 %), followed by CR Dhan 204 and 207, and AMF sporulation in CR Dhan 201 (31.98 spores / 10 gm soil) and CR Dhan 207 (30.29 spores / 10 g soil), as well as rice growth. The study showed that the highly responsive variety CR Dhan 207 followed by CR Dhan 204, 205, 201, and Kasalath IC459373 showed higher P uptake than the control, and AMF treated with 5.0 µM SL GR24 varieties CR Dhan 205 followed by CR Dhan 207 and 204 showed the best performance in plant growth, chlorophyll content, and soil functional properties, such as acid and alkaline phosphatase activity, soil microbial biomass carbon (MBC), dehydrogenase activity (DHA), and fluorescein diacetate activity (FDA). Overall, AMF intervention with SL GR24 significantly increased plant growth, soil enzyme activity, and uptake of P compared to the control. Under P-deficient conditions, seed priming with 5.0 µM strigolactone GR24 and AMF inoculum significantly increased selected aerobic rice growth, P uptake, and soil enzyme activities. Application of SLs formulations with AMF inoculum in selected aerobic rice varieties, CR Dhan 207, CR Dhan 204, and CR Dhan 205, will play an important role in mycorrhization, growth, and enhancement of P utilization under P- nutrient deficient conditions.</p></div>","PeriodicalId":34305,"journal":{"name":"Current Research in Microbial Sciences","volume":"6 ","pages":"Article 100229"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666517424000117/pdfft?md5=4a3ac5c456b421198ad5ce72c16433a4&pid=1-s2.0-S2666517424000117-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140122704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of novel bacterial metagenome-assembled genomes from lignin-degrading microbial consortia","authors":"Vitória Pinheiro Balestrini ,&nbsp;Otávio Henrique Bezerra Pinto ,&nbsp;Blake A. Simmons ,&nbsp;John M. Gladden ,&nbsp;Ricardo Henrique Krüger ,&nbsp;Betania Ferraz Quirino","doi":"10.1016/j.crmicr.2024.100302","DOIUrl":"10.1016/j.crmicr.2024.100302","url":null,"abstract":"<div><div>Despite recent progress, bacterial degradation of lignin is not completely understood. To address the mechanisms that bacteria from unknown taxonomic groups use to perform lignin-monomer degradation, functional analysis of bacterial metagenome-assembled genomes from soil-derived consortia enriched for microorganisms capable of degrading lignin was performed. A total of 232 metagenome-assembled genomes were recovered. After applying quality criteria of at least 70 % genome completeness and contamination less than or equal to 10 %, 39 genomes were obtained. From these, a total of 14 genomes from bacteria of unknown classification at lower taxonomic levels (i.e., only classified to the order level or higher) were chosen for further functional analysis. A global analysis of the potential ecological functions of these bacteria was performed, followed by a detailed analysis of monolignol degradation pathways. The phylum with the highest number of genomes was Proteobacteria. The genomes presented functions consistent with soil-derived bacteria, like denitrification, with different metabolic capacities related to the sulfur, chlorine, arsenic and carbon cycles, in addition to the degradation of plant cell wall components like cellulose, hemicellulose, and lignin. The Sphingomonadales_OP 08 genome showed the greatest potential to degrade cellulose and hemicellulose, although it does not appear to be able to degrade lignin. The Actinobacteria_BY 70 genome presented the highest number of enzymes and pathways related to the degradation of monolignols; furthermore, it showed the greatest potential for aromatic ring breakage by different fission pathways. The genomes of the two Actinobacteria showed the caffeic acid pathway, an important phenolic compound presenting several biological properties, such as antimicrobial and antioxidant. To our knowledge, this is the first time this pathway has been reported in this class of bacteria.</div></div>","PeriodicalId":34305,"journal":{"name":"Current Research in Microbial Sciences","volume":"7 ","pages":"Article 100302"},"PeriodicalIF":4.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is it time to re-evaluate exposure risks to quaternary ammonium compounds as disinfectants?","authors":"Jason A. Tetro ,&nbsp;Faraz A. Alderson ,&nbsp;Syed A. Sattar","doi":"10.1016/j.crmicr.2024.100258","DOIUrl":"https://doi.org/10.1016/j.crmicr.2024.100258","url":null,"abstract":"","PeriodicalId":34305,"journal":{"name":"Current Research in Microbial Sciences","volume":"7 ","pages":"Article 100258"},"PeriodicalIF":4.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666517424000403/pdfft?md5=28fa56f50989c7c932ecd98ac94404c8&pid=1-s2.0-S2666517424000403-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141582569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human cytomegalovirus and neonatal infection","authors":"Shelley M. Lawrence","doi":"10.1016/j.crmicr.2024.100257","DOIUrl":"https://doi.org/10.1016/j.crmicr.2024.100257","url":null,"abstract":"<div><p>Human cytomegalovirus is an ancient virus that has co-evolved with humans. It establishes a life-long infection in suspectable individuals for which there is no vaccination or cure. The virus can be transmitted to a developing fetus in seropositive pregnant women, and it is the leading cause of congenital infectious disease. While the majority of infected infants remain asymptomatic at birth, congenital cytomegalovirus infection can lead to substantial long-term neurodevelopmental impairments in survivors, resulting in considerable economic and social hardships. Recent discoveries regarding cytomegalovirus pathophysiology and viral replication cycles might enable the development of innovative diagnostics and therapeutics, including an effective vaccine. This Review will detail our understanding of human cytomegalovirus infection, with an in-depth discussion regarding the viral genome and transcriptome that contributes to its pathophysiology. The neonate's clinical course will also be highlighted, including maternal and neonatal testing, treatment recommendations, and long-term outcomes.</p></div>","PeriodicalId":34305,"journal":{"name":"Current Research in Microbial Sciences","volume":"7 ","pages":"Article 100257"},"PeriodicalIF":4.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666517424000397/pdfft?md5=ac750b4fff9e26378ae946408935652e&pid=1-s2.0-S2666517424000397-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141583042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An updated view of bacterial endophytes as antimicrobial agents against plant and human pathogens","authors":"Lalhmangaihmawia Hnamte ,&nbsp;Vanlallawmzuali ,&nbsp;Ajay Kumar ,&nbsp;Mukesh Kumar Yadav ,&nbsp;Zothanpuia ,&nbsp;Prashant Kumar Singh","doi":"10.1016/j.crmicr.2024.100241","DOIUrl":"10.1016/j.crmicr.2024.100241","url":null,"abstract":"<div><p>Bacterial endophytes are a crucial component of the phytomicrobiome, playing an essential role in agriculture and industries. Endophytes are a rich source of bioactive compounds, serving as natural antibiotics that can be effective in combating antibiotic resistance in pathogens. These bacteria interact with host plants through various processes such as quorum sensing, chemotaxis, antibiosis, and enzymatic activity. The current paper focuses on how plants benefit extensively from endophytic bacteria and their symbiotic relationship in which the microbes enhance plant growth, nitrogen fixation, increase nutrient uptake, improve defense mechanisms, and act as antimicrobial agents against pathogens. Moreover, it highlights some of the bioactive compounds produced by endophytes.</p></div>","PeriodicalId":34305,"journal":{"name":"Current Research in Microbial Sciences","volume":"7 ","pages":"Article 100241"},"PeriodicalIF":4.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666517424000233/pdfft?md5=7c2fc8440cd23aa2ccf5a5ee1423eff9&pid=1-s2.0-S2666517424000233-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141134688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}