iScience最新文献

筛选
英文 中文
The effectiveness of sound-based interventions on promoting sleep quality in hospitalized patients: A systematic review. 基于声音的干预对提高住院患者睡眠质量的有效性:一项系统综述。
IF 4.5 2区 综合性期刊
iScience Pub Date : 2026-09-22 eCollection Date: 2026-10-16 DOI: 10.1016/j.isci.2026.117698
Helga Rafael Henriques, Márcia Pereira Silva, Rui Guerreiro, Sílvia Caldeira Mendonça, Cândida Durão, Maria Rosario Pinto, Joana Teixeira
{"title":"The effectiveness of sound-based interventions on promoting sleep quality in hospitalized patients: A systematic review.","authors":"Helga Rafael Henriques, Márcia Pereira Silva, Rui Guerreiro, Sílvia Caldeira Mendonça, Cândida Durão, Maria Rosario Pinto, Joana Teixeira","doi":"10.1016/j.isci.2026.117698","DOIUrl":"10.1016/j.isci.2026.117698","url":null,"abstract":"<p><p>Sleep quality strongly affects hospitalized patients' recovery, yet pain, anxiety, and environmental factors such as noise and light frequently disrupt it. Sound-based therapies offer a promising, non-pharmacological approach, but their effectiveness has not been comprehensively synthesized. This systematic review examined fifteen studies (2012-2026, 2024 patients, mostly intensive care settings) evaluating sound-based interventions, including calming music, nature sounds, and white noise, on sleep quality. Intervention duration and timing varied widely, from brief five-minute sessions to continuous overnight administration, and sleep quality was most often measured using validated questionnaires. Despite substantial heterogeneity, sound-based interventions were associated with an overall improvement in sleep quality, although effect sizes varied considerably and several studies showed no significant benefit. These findings support the potential of low-cost, non-pharmacological sound interventions to improve sleep in hospital settings, while underscoring the need for further research to clarify which intervention characteristics drive effectiveness.</p>","PeriodicalId":342,"journal":{"name":"iScience","volume":"29 10","pages":"117698"},"PeriodicalIF":4.5,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13675385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149214936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impacts of trail running and mountain biking: Resilience of a Mediterranean mountain ecosystem. 越野跑和山地自行车的影响:地中海山地生态系统的恢复力。
IF 4.5 2区 综合性期刊
iScience Pub Date : 2026-09-22 eCollection Date: 2026-10-16 DOI: 10.1016/j.isci.2026.117721
Francisco Gómez-Prieto, Pablo Tejedo, Miguel Faucha, Adrián Escudero, Yu-Fai Leung, Fernando Valladares, Javier Benayas
{"title":"Impacts of trail running and mountain biking: Resilience of a Mediterranean mountain ecosystem.","authors":"Francisco Gómez-Prieto, Pablo Tejedo, Miguel Faucha, Adrián Escudero, Yu-Fai Leung, Fernando Valladares, Javier Benayas","doi":"10.1016/j.isci.2026.117721","DOIUrl":"10.1016/j.isci.2026.117721","url":null,"abstract":"<p><p>Rising outdoor activities have created major challenges for managing protected natural areas due to uncertain ecological effects. This study analyzes the impacts of two expanding sports, trail running and mountain biking, on flat and sloped terrains in a Mediterranean mountain setting in the Sierra de Guadarrama National Park, where transects were subjected to different use intensities. Early short-term impacts and subsequent recovery were monitored over a year using biotic and abiotic indicators: soil compaction, vegetation (total cover, Simpson's diversity index, and composition), bacterial colony-forming units, and edaphic microfauna. Results show that soil compaction and vegetation cover are the most affected among the variables analyzed, with significant alterations when applying a high number of passes on foot or by bicycle, but without significant differences between the two sports. Vegetation recovered faster than soil compaction, and Mediterranean seasonality strongly modulates impacts. Management measures are proposed to balance recreation and conservation.</p>","PeriodicalId":342,"journal":{"name":"iScience","volume":"29 10","pages":"117721"},"PeriodicalIF":4.5,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13661210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lateralized vagal oxytocin receptor signaling separately controls feeding and socioemotional functions via hypothalamic oxytocin neurons. 迷走神经侧侧催产素受体信号分别通过下丘脑催产素神经元控制进食和社会情绪功能。
IF 4.5 2区 综合性期刊
iScience Pub Date : 2026-09-22 eCollection Date: 2026-10-16 DOI: 10.1016/j.isci.2026.117713
Kengo Iba, Yuta Masuda, Rika Kitano, Kento Ohbayashi, Yukio Ago, Hirotaka Nagai, Tomoyuki Furuyashiki, Chikara Abe, Yusaku Iwasaki
{"title":"Lateralized vagal oxytocin receptor signaling separately controls feeding and socioemotional functions via hypothalamic oxytocin neurons.","authors":"Kengo Iba, Yuta Masuda, Rika Kitano, Kento Ohbayashi, Yukio Ago, Hirotaka Nagai, Tomoyuki Furuyashiki, Chikara Abe, Yusaku Iwasaki","doi":"10.1016/j.isci.2026.117713","DOIUrl":"https://doi.org/10.1016/j.isci.2026.117713","url":null,"abstract":"<p><p>Oxytocin neurons in the paraventricular hypothalamus (PVH<sup>Oxt</sup>) regulate feeding, anxiety, and social behaviors. Activation of Oxt receptor (Oxtr)-expressing vagal sensory neurons engages these PVH<sup>Oxt</sup> neurons and improves hyperphagic obesity; however, their roles in anxiety and sociability remain unclear. Here, we activated vagal Oxtr-expressing neurons in male mice using a single intraperitoneal (IP) Oxt injection or chemogenetics. IP Oxt reduced anxiety-like behavior, enhanced social interaction, and suppressed feeding while activating both vagal sensory neurons and PVH<sup>Oxt</sup> neurons. These effects were abolished by chemogenetic inhibition of PVH<sup>Oxt</sup> neurons or central Oxtr blockade. Subdiaphragmatic vagotomy revealed lateralized functions: right-side vagotomy eliminated anxiolytic and prosocial effects, whereas left-side vagotomy blocked feeding suppression. Consistently, chemogenetic activation of left-sided neurons suppressed feeding, while right-sided activation reduced anxiety and increased sociability. These findings identify Oxtr-expressing vagal sensory neurons as a major peripheral pathway in which left- and right-sided inputs differentially control feeding and socioemotional behaviors.</p>","PeriodicalId":342,"journal":{"name":"iScience","volume":"29 10","pages":"117713"},"PeriodicalIF":4.5,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13657252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Species-specific inflammatory responses of chondrocytes: Toward evidence-based model selection in OA research. 软骨细胞的物种特异性炎症反应:OA研究中基于证据的模型选择。
IF 4.5 2区 综合性期刊
iScience Pub Date : 2026-09-22 eCollection Date: 2026-10-16 DOI: 10.1016/j.isci.2026.117710
Angkana Kidtiwong, Maria-Belen Arteaga, Karyna Tarasova, Sinan Gültekin, Mario Rothbauer, Iris Gerner, Florien Jenner
{"title":"Species-specific inflammatory responses of chondrocytes: Toward evidence-based model selection in OA research.","authors":"Angkana Kidtiwong, Maria-Belen Arteaga, Karyna Tarasova, Sinan Gültekin, Mario Rothbauer, Iris Gerner, Florien Jenner","doi":"10.1016/j.isci.2026.117710","DOIUrl":"https://doi.org/10.1016/j.isci.2026.117710","url":null,"abstract":"<p><p>To inform evidence-based osteoarthritis model selection, this study compares inflammatory responses of articular chondrocytes from six species (human, horse, sheep, rabbit, rat, and mouse) under standardized IL-1β and TNF-α stimulation in 2D and 3D culture. Chondrocytes were assessed for viability, proliferation, wound healing, and transcriptomic changes via RT-qPCR and 3'RNA sequencing. Marked interspecies differences were observed in morphology, proliferation, and inflammatory gene activation, with only two genes (<i>SOD2</i>, <i>NFKBIA</i>) conserved across all species. Human, horse, and rat chondrocytes shared pathways including acute phase response, deubiquitination, and class-A/1-GPCR signaling. Species-specific responses included matrix remodeling in horses, rheumatoid arthritis-related pathways in sheep, and mixed inflammatory-regenerative profiles in rats. While no species fully replicates human OA, equine and rat chondrocytes best reflect key aspects of human inflammation. These findings underscore the need for molecular criteria in model selection and advocate for human cell-based models when interspecies differences limit the translational value of animal models.</p>","PeriodicalId":342,"journal":{"name":"iScience","volume":"29 10","pages":"117710"},"PeriodicalIF":4.5,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13657218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Climate vulnerability and governance impact the payoff of policy drivers for SDG 7 outcomes in BRICS countries. 气候脆弱性和治理影响金砖国家可持续发展目标7成果的政策驱动因素的回报。
IF 4.5 2区 综合性期刊
iScience Pub Date : 2026-09-22 eCollection Date: 2026-10-16 DOI: 10.1016/j.isci.2026.117700
Avik Sinha, Abhinav Jindal, Shujaat Abbas
{"title":"Climate vulnerability and governance impact the payoff of policy drivers for SDG 7 outcomes in BRICS countries.","authors":"Avik Sinha, Abhinav Jindal, Shujaat Abbas","doi":"10.1016/j.isci.2026.117700","DOIUrl":"10.1016/j.isci.2026.117700","url":null,"abstract":"<p><p>Achieving Sustainable Development Goal 7 (SDG 7) in large emerging economies requires energy policies that operate under diverse institutional and climatic conditions. We examine BRICS countries over 2000-2022 to assess how climate vulnerability and governance quality condition the estimated marginal effects of environmental policy stringency, innovation, financial development, inequality, and demographic structure on energy access, renewable energy, and energy efficiency. A two-stage empirical framework combines moderated GLS estimation with post-estimation evaluation of marginal-effect surfaces across contrasting governance-vulnerability regimes and country-specific conditions. The results show that stronger governance and lower climate vulnerability are generally associated with more favorable estimated effects of finance, innovation, and policy stringency, while weak governance and high vulnerability can weaken or reverse these relationships. Policy priorities also differ across SDG 7 subgoals and BRICS economies. These findings support context-specific energy policies that align institutional strengthening and climate resilience with SDG 7 implementation.</p>","PeriodicalId":342,"journal":{"name":"iScience","volume":"29 10","pages":"117700"},"PeriodicalIF":4.5,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13673360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149214820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Massive histone H3 phosphorylation without mitotic chromosome condensation. 大量组蛋白H3磷酸化,没有有丝分裂染色体凝聚。
IF 4.5 2区 综合性期刊
iScience Pub Date : 2026-09-22 eCollection Date: 2026-10-16 DOI: 10.1016/j.isci.2026.117718
Ipek Ustun, Marco Borsò, Natalia Y Kochanova, Ignasi Forne, Caitlin Reid, Bram Prevo, Kumiko Samejima, Linfeng Xie, James R Paulson, Axel Imhof, William C Earnshaw
{"title":"Massive histone H3 phosphorylation without mitotic chromosome condensation.","authors":"Ipek Ustun, Marco Borsò, Natalia Y Kochanova, Ignasi Forne, Caitlin Reid, Bram Prevo, Kumiko Samejima, Linfeng Xie, James R Paulson, Axel Imhof, William C Earnshaw","doi":"10.1016/j.isci.2026.117718","DOIUrl":"10.1016/j.isci.2026.117718","url":null,"abstract":"<p><p>Histone post-translational modifications change dramatically as cells enter mitosis. Indeed, histone phosphorylation and deacetylation have been proposed to be major factors driving the compaction of mitotic chromosomes. However, whether these modification changes directly regulate mitotic chromatin compaction remains a subject of debate. Here, we use a CDK1<sup>as</sup> chemical-genetic system to accumulate cells in G<sub>2</sub> phase. Treatment of these G<sub>2</sub> cells with the phosphatase inhibitor calyculin A efficiently causes them to undergo premature chromosome condensation, even when the CDK1<sup>as</sup> allele is inhibited with 1NM-PP1. Surprisingly, simultaneous treatment of the cells with R547, an inhibitor of CDK1, 2, and 4 kinases, causes them to remain phenotypically in G<sub>2</sub> phase. Strikingly, although mitotic-like chromatin condensation fails to occur in these cells, LC-MS reveals that histone H3 phosphorylation occurs even more efficiently than in a normal mitosis. Furthermore, histone deacetylation also occurs in those interphase-looking calyculin A-treated cells. These results reveal that histone phosphorylation and deacetylation are not sufficient to drive mitotic-like chromosome condensation and compaction.</p>","PeriodicalId":342,"journal":{"name":"iScience","volume":"29 10","pages":"117718"},"PeriodicalIF":4.5,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13675386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149214882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rhizobacterial biocontrol of potato late blight and genomic insights into disease suppression and growth promotion. 马铃薯晚疫病的根瘤菌生物防治及其抑制和促进生长的基因组研究。
IF 4.5 2区 综合性期刊
iScience Pub Date : 2026-09-22 eCollection Date: 2026-10-16 DOI: 10.1016/j.isci.2026.117682
Bekele Gelena Kelbessa, Samrat Ghosh, Farideh Ghadamgahi, Vittoria Catara, Stephen C Whisson, Rodomiro Ortiz, Ramesh Raju Vetukuri
{"title":"Rhizobacterial biocontrol of potato late blight and genomic insights into disease suppression and growth promotion.","authors":"Bekele Gelena Kelbessa, Samrat Ghosh, Farideh Ghadamgahi, Vittoria Catara, Stephen C Whisson, Rodomiro Ortiz, Ramesh Raju Vetukuri","doi":"10.1016/j.isci.2026.117682","DOIUrl":"10.1016/j.isci.2026.117682","url":null,"abstract":"<p><p>Late blight caused by <i>Phytophthora infestans</i> remains a major challenge to sustainable potato production. In this study, we evaluated five bacterial strains for their ability to reduce late blight and improve potato growth under field, <i>in vitro</i>, detached-leaf, and greenhouse conditions. All tested strains reduced disease severity, with <i>Serratia rubidaea</i> AV10 showing particularly strong antagonistic activity and consistent suppression of disease. Genome sequencing of the two potato-associated strains, AV10 and <i>S. rubidaea</i> EV23, revealed biosynthetic clusters and genes potentially linked to antimicrobial activity, siderophore production, biofilm formation, nutrient acquisition, and plant growth promotion. Bacterial treatment also influenced the expression of potato genes associated with jasmonic acid, ethylene, salicylic acid-related defense, and auxin-linked growth response. Together, these findings identify AV10 and EV23 as promising rhizobacterial candidates for integrated late blight management and provide genomic insight into traits that may contribute to disease suppression and plant growth promotion.</p>","PeriodicalId":342,"journal":{"name":"iScience","volume":"29 10","pages":"117682"},"PeriodicalIF":4.5,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13675477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149214917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dysregulation of neuronal androgen receptor signaling by divergent collaborative transcription factors in Alzheimer's disease. 阿尔茨海默病中不同协同转录因子介导的神经元雄激素受体信号失调。
IF 4.5 2区 综合性期刊
iScience Pub Date : 2026-09-22 eCollection Date: 2026-10-16 DOI: 10.1016/j.isci.2026.117731
Kenichi Takayama, Yutaka Suzuki, Yuko Saito, Takashi Suzuki, Shuichi Tsutsumi, Hiroyuki Aburatani, Satoshi Inoue
{"title":"Dysregulation of neuronal androgen receptor signaling by divergent collaborative transcription factors in Alzheimer's disease.","authors":"Kenichi Takayama, Yutaka Suzuki, Yuko Saito, Takashi Suzuki, Shuichi Tsutsumi, Hiroyuki Aburatani, Satoshi Inoue","doi":"10.1016/j.isci.2026.117731","DOIUrl":"10.1016/j.isci.2026.117731","url":null,"abstract":"<p><p>The transcriptional mechanisms through which androgens and androgen receptor (AR) exert specific effects on human tissues remain elusive. Here, we demonstrated that neuronal cell-specific transcription factors (TFs) may play an important role as epigenetic modifiers that shape the AR cistrome during neuronal activity. The binding of GATA3 to specific regulatory sequences in human neuronal cell models is associated with enhanced AR-mediated transcription. AR-binding sites (ARBSs) are enriched in regions overlapping with super-enhancers (SEs) that encode critical neuronal factors. Furthermore, AR signaling in aged human male brains indicates its role in supporting neural function and declines during the progression of Alzheimer's disease (AD). The expression levels of AR-associated TFs were dysregulated during aging and AD development. Altered expression of TFs may contribute to disruption of AR signaling. Thus, collaborative TFs could contribute to the neuronal androgen response and epigenetic regulation involved in aging and the progression of dementia.</p>","PeriodicalId":342,"journal":{"name":"iScience","volume":"29 10","pages":"117731"},"PeriodicalIF":4.5,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13661227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contrasting fate and GHG emissions of algal vs. manure DOM under light and microbes in lakes. 湖泊光照和微生物条件下藻类与粪肥DOM的命运和温室气体排放对比。
IF 4.5 2区 综合性期刊
iScience Pub Date : 2026-09-22 eCollection Date: 2026-10-16 DOI: 10.1016/j.isci.2026.117674
Yulong Tao, Qianyong Wang, Muren Bao, Yutong Tian, Lu Lu
{"title":"Contrasting fate and GHG emissions of algal vs. manure DOM under light and microbes in lakes.","authors":"Yulong Tao, Qianyong Wang, Muren Bao, Yutong Tian, Lu Lu","doi":"10.1016/j.isci.2026.117674","DOIUrl":"https://doi.org/10.1016/j.isci.2026.117674","url":null,"abstract":"<p><p>The escalating dissolved organic matter (DOM) inputs from algal (ADOM) and livestock manure (MDOM) sources are altering lake ecosystems, yet their fate under light and microbes in steppe lakes is unclear. Using microcosms, we found that photodegradation suppressed ADOM bioavailability by 4.8% via substrate competition and reactive oxygen species (ROS) inhibition (especially singlet oxygen), while light enhanced MDOM bioavailability by 5.4%. ADOM mineralization released 1.6× more CO<sub>2</sub> than MDOM. Multi-group structural equation modeling (SEM) indicated that efficient ADOM microbial transformation drove higher CO<sub>2</sub> emissions, whereas light-induced ROS shifted microbial communities and transformation pathways. ADOM and MDOM inputs predominantly enhanced CO<sub>2</sub> emissions and water browning, respectively. These processes are interconnected-exogenous MDOM can promote algal blooms and subsequent greenhouse gas release. For eutrophic steppe lakes, integrated management combining exogenous load reduction and endogenous bloom suppression is critical to mitigate ecological risks and greenhouse effects.</p>","PeriodicalId":342,"journal":{"name":"iScience","volume":"29 10","pages":"117674"},"PeriodicalIF":4.5,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13657346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resveratrol-mediated Fe(III)/peroxydisulfate activation for ofloxacin degradation at circumneutral pH. 白藜芦醇介导的铁(III)/过硫酸氢盐活化在环中性pH下降解氧氟沙星。
IF 4.5 2区 综合性期刊
iScience Pub Date : 2026-09-22 eCollection Date: 2026-10-16 DOI: 10.1016/j.isci.2026.117733
Yanlin Wu, Wenyu Yang, Yilan Zeng, Dingfeng Huang, Wenbo Dong, Olivier Monfort, Martin Motola
{"title":"Resveratrol-mediated Fe(III)/peroxydisulfate activation for ofloxacin degradation at circumneutral pH.","authors":"Yanlin Wu, Wenyu Yang, Yilan Zeng, Dingfeng Huang, Wenbo Dong, Olivier Monfort, Martin Motola","doi":"10.1016/j.isci.2026.117733","DOIUrl":"10.1016/j.isci.2026.117733","url":null,"abstract":"<p><p>Iron-mediated peroxydisulfate (PDS) activation is limited by slow Fe(III)/Fe(II) redox cycling under circumneutral conditions. Here, resveratrol (RES), a natural stilbene polyphenol, was introduced as a low-dose redox mediator to promote Fe(II) formation from Fe(III) for enhanced PDS activation. The Fe(III)/RES/PDS system showed higher ofloxacin (OFL) degradation than the corresponding single-reagent and binary systems and achieved approximately 90% OFL degradation at pH 6.5. Chemical quenching and competition-kinetic analysis indicated that sulfate radical (SO<sub>4</sub> <sup>·-</sup>) was the major contributor to OFL degradation, while hydroxyl radical (<sup>·</sup>OH) played a secondary role. Matrix experiments showed that Cl<sup>-</sup> and NO<sub>3</sub> <sup>-</sup> had minor effects, whereas NO<sub>2</sub> <sup>-</sup> strongly inhibited OFL degradation. This work provides a case study of RES-mediated Fe(III)/PDS activation for antibiotic degradation under near-neutral conditions.</p>","PeriodicalId":342,"journal":{"name":"iScience","volume":"29 10","pages":"117733"},"PeriodicalIF":4.5,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13671365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149214914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书