Dyes and Pigments最新文献_第4页

A red fluorescent probe for lipid droplet polarity sensitivity and identification of nonalcoholic fatty liver disease 一种用于脂滴极性敏感性和非酒精性脂肪肝鉴别的红色荧光探针

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-07-17 DOI: 10.1016/j.dyepig.2025.113048

Kun Yu , Jie Wang , Yuqing Wang , Jing Yang , Chunfei Wang , Lei Hu , Hui Wang

{"title":"A red fluorescent probe for lipid droplet polarity sensitivity and identification of nonalcoholic fatty liver disease","authors":"Kun Yu , Jie Wang , Yuqing Wang , Jing Yang , Chunfei Wang , Lei Hu , Hui Wang","doi":"10.1016/j.dyepig.2025.113048","DOIUrl":"10.1016/j.dyepig.2025.113048","url":null,"abstract":"<div><div>The increasing prevalence of non-alcoholic fatty liver disease (NAFLD) has attracted widespread attention in recent years. As critical intracellular sites for energy storage, lipid droplets (LDs) have become one of the important biomarkers for early diagnosis of NAFLD. Therefore, a series of fluorescent probes (<strong>WL1</strong>-<strong>WL3</strong>) with D-π-A-D and D-π-A structures were designed and synthesized in this study. Photophysical property studies shown that all these probes are highly sensitive to polarity and insensitive to various analytes and pH changes. Among them, probe <strong>WL3</strong> showed excellent optical properties, with an emission wavelength in the near-infrared region (>650 nm), a large Stokes shift, and a good linear correlation between fluorescence intensity and solvent polarity. Further biological results demonstrated that probe <strong>WL3</strong> not only monitors alterations in the number and size of LDs, but also detects variations in the polarity of intracellular LDs and dynamically tracks LDs-related processes (LDs autophagy). In a NAFLD cell model, probe <strong>WL3</strong> could effectively monitor the efficacy of metformin (Met) in the treatment of NAFLD. Furthermore, probe <strong>WL3</strong> was able to clearly distinguish normal liver from NAFLD at both the tissue and organ level, demonstrating its promising potential for clinical potential.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"243 ","pages":"Article 113048"},"PeriodicalIF":4.1,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Highly stable Aza-BODIPY dyes for near-infrared-II PAI/FLI guided efficient tumor photothermal therapy 高度稳定的Aza-BODIPY染料用于近红外ii PAI/FLI引导的高效肿瘤光热治疗

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-07-16 DOI: 10.1016/j.dyepig.2025.113018

Yunjian Xu , Ke Xu , Zhen Wang , Yajie Zhang , Jia Chen , Menglong Zhao , Jianfeng Qiu

{"title":"Highly stable Aza-BODIPY dyes for near-infrared-II PAI/FLI guided efficient tumor photothermal therapy","authors":"Yunjian Xu , Ke Xu , Zhen Wang , Yajie Zhang , Jia Chen , Menglong Zhao , Jianfeng Qiu","doi":"10.1016/j.dyepig.2025.113018","DOIUrl":"10.1016/j.dyepig.2025.113018","url":null,"abstract":"<div><div>Fluorescence imaging (FLI) and photoacoustic imaging (PAI) in the near-infrared-II (NIR-II) window offer significant superiorities, including non-invasiveness and deep tissue penetration, which are beneficial for guiding highly efficient tumor photothermal therapy (PTT). Herein, utilizing photoinduced electron transfer (PET) and vibration relaxation effect, a NIR-II therapeutic agent based on aza-BODIPY dyes is rationally constructed by bonding diethylaminobenzene with strong electron supply capability, small spatial skeleton of conjugated aromatic rings, aza-BODIPY core, and triethylene glycol monomethyl ether (TGME). <strong>Aza NPs</strong> with enhanced loading rates is obtained for biological application by introducing TGME. <strong>Aza NPs</strong> with concentration-dependence linear NIR-II fluorescence and photoacoustic signals, excellent resistance to reactive oxygen nitrogen species exhibits a high photothermal conversion efficiency of 53.3 %. Finally, guided by the superior NIR-II FLI and PAI, HeLa tumors were effectively eliminated by the super photothermal conversion performance of <strong>Aza NPs</strong>. This work proposes that PET and vibration relaxation effect are very important theoretical guidance to construct aza-BODIPY-based NIR-II therapeutic agent for tumor PTT, which lays the foundation for the clinical application development of small-molecule organic nanomedicines. It also provides new ideas for the diagnosis and treatment of deep-located tumors through the NIR-II FLI & PAI guidance.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"243 ","pages":"Article 113018"},"PeriodicalIF":4.1,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144662156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, characterisation and application of red-emitting BODIPY dyes for multiphoton microscopy of lipid droplets 脂滴多光子显微镜用红发BODIPY染料的合成、表征及应用

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-07-16 DOI: 10.1016/j.dyepig.2025.113045

Paolo J. Mastroeni , Connor B. Armstrong , Dominic J. Black , Atticus Strickland , Michael Hall , Toby Blundell , Natalie E. Pridmore , Robert Pal , Patrycja Stachelek

{"title":"Synthesis, characterisation and application of red-emitting BODIPY dyes for multiphoton microscopy of lipid droplets","authors":"Paolo J. Mastroeni , Connor B. Armstrong , Dominic J. Black , Atticus Strickland , Michael Hall , Toby Blundell , Natalie E. Pridmore , Robert Pal , Patrycja Stachelek","doi":"10.1016/j.dyepig.2025.113045","DOIUrl":"10.1016/j.dyepig.2025.113045","url":null,"abstract":"<div><div>This study introduces two novel red-emissive BODIPY dyes, each functionalized with methoxystyryl groups at the 3- and 5-positions to bathochromically shift spectral bands. Obtained via facile synthetic pathways, the dyes can be excited using red single-photon or near-infrared two-photon excitation. The latter is of key importance, with long-wavelength excitation being advantageous for live-cell microscopy as it offers increased tissue penetration, reduced scattering, and minimal autofluorescence.</div><div>Comprehensive structural, computational, and photophysical characterisation highlight the suitability of both dyes for use in live-cell laser scanning confocal microscopy (LSCM) of mouse embryonic fibroblast (NIH-3T3) cells. The materials are characterised by high brightness with high molar absorption coefficients and photoluminescence quantum yields. Additionally, two-photon absorption cross-sections were measured as 723 GM and 502 GM (1 GM = 10<sup>–50</sup> cm<sup>4</sup> s photon<sup>−1</sup>) at 840 nm, respectively, making the dyes suitable for multiphoton microscopy applications.</div><div>Dosing protocols were developed for single-photon and multiphoton LSCM, and co-staining confirmed strong localisation within lipid droplets (LDs). LDs are an important organelle to study regarding manifestation of diseases such as diabetes and cancer, as well as monitoring of distribution of lipophilic intracellular material. Cytotoxicity assays at a range of concentrations (500 nM – 5 μM) for up to 24 h revealed both dyes can be used for prolonged live-cell microscopy without significant alterations to cellular viability.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"243 ","pages":"Article 113045"},"PeriodicalIF":4.1,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144679717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New mixed ligand based Cd(II) coordination polymer: An apt reversible turn-off-on photoluminescent sensor for dopamine and 2-hydroxybenzoic acid 新型混合配体基Cd（II）配位聚合物：一种适合于多巴胺和2-羟基苯甲酸的可逆开关光致发光传感器

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-07-16 DOI: 10.1016/j.dyepig.2025.113037

Ren-Min Ma , Jing Luo , Xin Song , Jun Wang , Mohammad Khalid Parvez , Mohammed S. Al-Dosari , Manoj Trivedi , Daniel Omoding , Abhinav Kumar

{"title":"New mixed ligand based Cd(II) coordination polymer: An apt reversible turn-off-on photoluminescent sensor for dopamine and 2-hydroxybenzoic acid","authors":"Ren-Min Ma , Jing Luo , Xin Song , Jun Wang , Mohammad Khalid Parvez , Mohammed S. Al-Dosari , Manoj Trivedi , Daniel Omoding , Abhinav Kumar","doi":"10.1016/j.dyepig.2025.113037","DOIUrl":"10.1016/j.dyepig.2025.113037","url":null,"abstract":"<div><div>A new Cd(II)-coordination polymer (CP) having formula [Cd<sub>2</sub>(L)(HL)(Hbpa)(H<sub>2</sub>O)·3H<sub>2</sub>O]<sub>n</sub> (<strong>1</strong>) have been synthesized using 5-(4′-carboxylphenoxy) isophthalic acid (H<sub>3</sub>L) and bis(4-pyridyl)amine (bpa) ligands and characterized. The crystallographic study reveals that CP <strong>1</strong> possess two Cd<sup>2+</sup> centers in asymmetric unit in which one is six coordinate whilst other adopts seven coordinate mode. The CP <strong>1</strong> exhibits <em>turn-off</em> photoluminescent sensing in presence of dopamine (DA) showcasing limit of detection and <em>K</em><sub>SV</sub> of 4.69 × 10<sup>−4</sup> M and 204.46346 M<sup>-1</sup>, respectively. Interestingly, the DA@<strong>1</strong> exhibited restoration in photoluminescent emission on adding salicylic acid (2-hyd acid) and hence can be used as <em>turn-on</em> photoluminescent sensor for the selective and sensitive detection of 2-hyd acid with limit of detection 3.37 × 10<sup>−4</sup> M with <em>K</em><sub>SV</sub> value of 282.45426. Theoretical calculations indicate that the <em>turn-off</em> sensing of DA by <strong>1</strong> have been accredited to the energy and charge transfer from <strong>1</strong> to DA along-with non-covalent interactions between <strong>1</strong> and DA. The restoration in photoluminescence intensity of DA@<strong>1</strong> on adding 2-hyd acid has been accredited to the removal of DA from matrix of <strong>1</strong>.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"243 ","pages":"Article 113037"},"PeriodicalIF":4.1,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144656634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reversible fluorescent probes for monitoring hypochlorous acid/ glutathione redox cycling and viscosity dynamics during mitophagy 用于监测次氯酸/谷胱甘肽氧化还原循环和线粒体自噬过程粘度动力学的可逆荧光探针

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-07-16 DOI: 10.1016/j.dyepig.2025.113047

Chao Fu, Liu Yang, Xiangzhi Song

{"title":"Reversible fluorescent probes for monitoring hypochlorous acid/ glutathione redox cycling and viscosity dynamics during mitophagy","authors":"Chao Fu, Liu Yang, Xiangzhi Song","doi":"10.1016/j.dyepig.2025.113047","DOIUrl":"10.1016/j.dyepig.2025.113047","url":null,"abstract":"<div><div>Mitophagy, a selective autophagy process that removes and recycles damaged mitochondria, is closely associated with fluctuations in the hypochlorous acid (HClO)/glutathione (GSH) redox pair and viscosity. Therefore, monitoring of HClO/GSH and viscosity during mitophagy could provide dynamic insights into the mitophagy mechanism and function. Herein, three novel fluorescent probes (<strong>PSeZ-Py</strong>, <strong>PSeZ-ID</strong>, and <strong>PSeZ-QN</strong>) were developed for reversibly detecting HClO and viscosity. Upon the treatment of HClO/GSH redox pair, the probes exhibited a reversible fluorescence signal due to the redox state transition of the selenium (Se) atom. Moreover, the fluorescence signal of oxidized <strong>PSeZ-QN</strong> could be further amplified under high-viscosity conditions via twisted intramolecular charge transfer (TICT) mechanism. Notably, <strong>PSeZ-QN</strong> achieved 91-fold and 531-fold fluorescent enhancement at 648 nm towards HClO and viscosity, respectively, and the probe could maintain fluorescence on-off transitions over four redox cycles. Furthermore, <strong>PSeZ-QN</strong> displays excellent biocompatibility and enables the detection of both exogenous and endogenous HClO/GSH in HeLa cells. After treated with Nystatin to induce high viscosity environment, a significantly enhanced fluorescence signal in cells was observed. Overall, <strong>PSeZ-QN</strong> could help to shed further light on the imaging of the mitochondrial autophagy process, providing a valuable tool for studying the dynamics in mitophagy.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"243 ","pages":"Article 113047"},"PeriodicalIF":4.1,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144665476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design, synthesis of novel unsymmetrical and NIR-emissive BF2 complexes and application in hydrazine detection 新型非对称近红外发射BF2配合物的设计、合成及其在联氨检测中的应用

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-07-16 DOI: 10.1016/j.dyepig.2025.113042

Furong Xie , Yiyi Zhang , Lingyun Wang , Xueguang Ran , Derong Cao

{"title":"Design, synthesis of novel unsymmetrical and NIR-emissive BF2 complexes and application in hydrazine detection","authors":"Furong Xie , Yiyi Zhang , Lingyun Wang , Xueguang Ran , Derong Cao","doi":"10.1016/j.dyepig.2025.113042","DOIUrl":"10.1016/j.dyepig.2025.113042","url":null,"abstract":"<div><div>We report a facile synthetic route towards novel unsymmetrical and NIR-emissive BF<sub>2</sub> complexes (<strong>PPAB1-Cy1</strong>, <strong>PPAB1-Cy2</strong> and <strong>PPAB1-Cy3</strong>) from diketopyrrolopyrrole (DPP) as a starting material. The outstanding character such as high molar extinction coefficient (up to 1.31∗10<sup>5</sup> M<sup>−1</sup>cm<sup>−1</sup>), large Stokes shift and high fluorescence quantum yield was obtained. Moreover, <strong>PPAB1-Cy1</strong> showed highly efficient detection towards hydrazine, leading to excellent sensing performances (a low limit of detection of 4.53 nM, fast response, good selectivity, and dual colormetric/ratiometic fluorescence signals). The sensing mechanism revealed that hydrazine-triggered elimination of acrylonitrile group, multiple B–N detachment and hydrolysis of C<img>N would synergistically occur between <strong>PPAB1-Cy1</strong> and hydrazine, leading to less conjugated products. Furthermore, <strong>PPAB1-Cy1</strong> could detect hydrazine content in real samples (soil, lake water and tap water) with good recovery rate. The quantitative detection and analysis of hydrazine vapor/solution or hydrazine contaminated sandy soil with <strong>PPAB1-Cy1</strong> loaded filter paper, sponge, or silica gel <em>via</em> a smartphone application.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"243 ","pages":"Article 113042"},"PeriodicalIF":4.1,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144656633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ether-mediated charge transfer modulation for deep-blue multi-resonance TADF emitters with enhanced reverse intersystem crossing 具有增强反向系统间交叉的深蓝色多共振TADF发射器的醚介导电荷转移调制

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-07-16 DOI: 10.1016/j.dyepig.2025.113019

Yaozu Su , Guowei Chen , Jie Hu , Si-Wei Chen , Lu Zhou , Xiaofeng Tan , Jiacong Liu , Longjiang Xing , Jia-Ming Jin , Ruicheng Wang , Shangru Li , Wen-Cheng Chen , Shaomin Ji , Hao-Li Zhang , Yanping Huo

{"title":"Ether-mediated charge transfer modulation for deep-blue multi-resonance TADF emitters with enhanced reverse intersystem crossing","authors":"Yaozu Su , Guowei Chen , Jie Hu , Si-Wei Chen , Lu Zhou , Xiaofeng Tan , Jiacong Liu , Longjiang Xing , Jia-Ming Jin , Ruicheng Wang , Shangru Li , Wen-Cheng Chen , Shaomin Ji , Hao-Li Zhang , Yanping Huo","doi":"10.1016/j.dyepig.2025.113019","DOIUrl":"10.1016/j.dyepig.2025.113019","url":null,"abstract":"<div><div>Multi-resonance thermally activated delayed fluorescence (MR-TADF) materials have garnered significant attention in the field of wide-color-gamut displays due to their high luminescent efficiency and narrowband emission characteristics. However, the development of deep-blue emitters that simultaneously achieve high efficiency and high color purity remains a critical challenge. In this work, we propose an ether-mediated long-range charge transfer strategy to develop two novel MR-TADF blue emitters, <strong>BNCz-OPh</strong> and <strong>BNCz-OTPA</strong>. By synergistically modulating the weak electron-donating effect of oxygen atom and the moderate electron-donating capability of triphenylamine groups, we achieved blue-shifted emission wavelengths and enhanced exciton utilization efficiency while maintaining narrowband emission. The ether bridge can accelerate the reverse intersystem crossing process through charge transfer, thereby optimizing exciton dynamics. The <strong>BNCz-OTPA</strong>-based OLED device exhibited narrowband emission with a full width at half maximum (FWHM) of 26 nm. Commission Internationale de l’Éclairage (CIE) coordinates of (0.118, 0.148), and a maximum external quantum efficiency (EQE) of 25.2 %. This work provides a new design strategy for high-performance narrowband blue organic light-emitting diodes with good color purity and efficiency.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"243 ","pages":"Article 113019"},"PeriodicalIF":4.1,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144685641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A highly sensitive near-infrared fluorescent probe for intelligent visual detection of Cu2+ in water/vegetables and bioimaging in vitro and in vivo 一种高灵敏度近红外荧光探针，用于水/蔬菜中Cu2+的智能视觉检测和体内外生物成像

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-07-15 DOI: 10.1016/j.dyepig.2025.113033

Yan-Jun Zhu, Pan Pan, Bin Zhang, Jia-Xing Lu, Jing Wang, Ao Shen, Xin-Mei Li, Ai-Ping Xing, Dai Zeng, Juan Yuan

{"title":"A highly sensitive near-infrared fluorescent probe for intelligent visual detection of Cu2+ in water/vegetables and bioimaging in vitro and in vivo","authors":"Yan-Jun Zhu, Pan Pan, Bin Zhang, Jia-Xing Lu, Jing Wang, Ao Shen, Xin-Mei Li, Ai-Ping Xing, Dai Zeng, Juan Yuan","doi":"10.1016/j.dyepig.2025.113033","DOIUrl":"10.1016/j.dyepig.2025.113033","url":null,"abstract":"<div><div>A “turn-on” NIR fluorescent probe <strong>NRK-BD</strong> for Cu<sup>2+</sup> based on the xanthene skeleton was successfully developed. <strong>NRK-BD</strong> was characterized by <sup>1</sup>H NMR, <sup>13</sup>C NMR and ESI-HRMS. Spectral experiments were conducted in MeCN/H<sub>2</sub>O (7:3, v/v, pH = 7.4) solution. The results revealed that <strong>NRK-BD</strong> possessed a large Stokes shift of 170 nm, a rapid response within 1.5 s and a low detection limit of 81 nM, which significantly enhanced the sensitivity and detection efficiency towards Cu<sup>2+</sup>. Within the concentration range of 0–20 μM, a favorable linear correlation was exhibited between the fluorescence intensity and the concentration of Cu<sup>2+</sup>. Moreover, <strong>NRK-BD</strong> demonstrated excellent stability in the pH range of 6.5–8.5, making it suitable for the detection of Cu<sup>2+</sup> under physiological conditions. <strong>NRK-BD</strong> coordinated with Cu<sup>2+</sup> in a 1:1 ratio, and the possible recognition mechanism was verified by Job's plot, ESI-HRMS and DFT calculations. Based on the color change of <strong>NRK-BD</strong> from colorless to purple, the naked-eye visual detection of Cu<sup>2+</sup> in vegetables such as brassica chinensis, potatoes and carrots was successfully achieved. A smart detection platform was also developed, which was capable of rapidly and quantitatively detecting Cu<sup>2+</sup> in actual water samples. It is noteworthy that <strong>NRK-BD</strong> was successfully applied to the fluorescence imaging of Cu<sup>2+</sup> in 4T1 cells and living mice. In summary, <strong>NRK-BD</strong> manifested outstanding performance in the detection of Cu<sup>2+</sup> and holds broad application prospects.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"243 ","pages":"Article 113033"},"PeriodicalIF":4.1,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144665814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanochemical synthesis and optical properties of solvatochromic 2H-indazole-3,5-diones 溶剂致变色2h -吲哚-3,5-二酮的机械化学合成及光学性质

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-07-15 DOI: 10.1016/j.dyepig.2025.113044

Sara Morasi Piperčić , Alen Bjelopetrović , Marina Juribašić Kulcsár

引用次数: 0

Development of a near-infrared ratiometric fluorescent probe for the detection of ONOO− in ferroptosis model 用于铁下垂模型中ONOO−检测的近红外比例荧光探针的研制

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-07-15 DOI: 10.1016/j.dyepig.2025.113041

Guo-Ping Zu , Pingping Xiong , Meng-Chen Pei , Chengjie Wang , Huawei Niu , Hong Chen , Yong Meng

{"title":"Development of a near-infrared ratiometric fluorescent probe for the detection of ONOO− in ferroptosis model","authors":"Guo-Ping Zu , Pingping Xiong , Meng-Chen Pei , Chengjie Wang , Huawei Niu , Hong Chen , Yong Meng","doi":"10.1016/j.dyepig.2025.113041","DOIUrl":"10.1016/j.dyepig.2025.113041","url":null,"abstract":"<div><div>Peroxynitrite (ONOO<sup>−</sup>) is closely associated with several pathophysiological events due to its high oxidation and nitrification reactivity, which can cause irreparable damage to a variety of biomolecules when present in excess. Consequently, the development of a reliable ONOO<sup>−</sup> detection method is essential for understanding its role. Given the significant imaging advantages of ratiometric and near-infrared (NIR) probes, a ratiometric NIR fluorescence probe (<strong>FYS</strong>) was developed for the visual detection of ONOO<sup>−</sup> both <em>in vitro</em> and <em>in vivo</em>. Probe <strong>FYS</strong> offers several benefits, including a large fluorescence emission shift (184 nm), a low detection limit (0.75 μM), good selectivity, and rapid detection. Inspired by these outstanding characteristics, it has been successfully utilized for imaging endogenous and exogenous ONOO<sup>−</sup> in cells. More importantly, this probe could be used to monitor variations in ONOO<sup>−</sup> levels as ferroptosis progresses. We anticipate that this probe will be widely applied as a potent tool to investigate the biological function of ONOO<sup>−</sup>, thereby facilitating a deeper understanding of ferroptosis.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"243 ","pages":"Article 113041"},"PeriodicalIF":4.1,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144656636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0