Dyes and Pigments最新文献

{"title":"Development of a novel dual fluorescent probe: mitochondrial targeting and iron chelator","authors":"Camilo Segura ,&nbsp;Osvaldo Yañez ,&nbsp;Pamela J. Urrutia ,&nbsp;Pabla Aguirre ,&nbsp;María Quilaqueo ,&nbsp;Marco T. Núñez ,&nbsp;Juan Hinestroza ,&nbsp;Margarita Aliaga ,&nbsp;Ramón Martínez-Máñez ,&nbsp;Olimpo García-Beltrán","doi":"10.1016/j.dyepig.2026.113644","DOIUrl":"10.1016/j.dyepig.2026.113644","url":null,"abstract":"<div><div>We report the design, synthesis, and characterization of YBL-1, a coumarin–triphenylphosphonium (TPP⁺) fluorescent probe engineered for mitochondrial targeting and iron sensing. YBL-1 was obtained through a three-step sequence culminating in quaternization with (bromomethyl)triphenylphosphonium bromide. Steady-state photophysics reveal minimal solvatochromism (λ_abs 348–355 nm; λ_em 401–408 nm) and allowed transitions (ε_max ≈ 2.2–2.6 × 10⁴ M⁻¹ cm⁻¹). The probe remains bright in water, with high quantum yields (Φ_F ≈ 0.76). Screening against common metal cations indicates a pronounced and selective turn-off response to Fe³⁺. Job's analysis supports 1:1 complexation, and Benesi–Hildebrand treatment (1:1 model) indicates a modest association constant on the order of 10² M⁻¹ in water. Complementary quantum-chemical calculations support a predominantly π→π∗ locally excited S₁ state with only weak charge-transfer character, consistent with the small solvatochromism. Electrostatic potential maps and population analyses highlight the carbonyl/urea/alkoxy region as the primary hard-donor site, rationalizing Fe³⁺ binding; simple adduct models in water predict modest stabilization in line with the measured Ka and a rigidified complex consistent with static quenching. In SH-SY5Y cells co-stained with MitoTracker Red, YBL-1 colocalizes strongly with mitochondria (Pearson r ≈ 0.95), consistent with TPP⁺-driven membrane-potential-mediated accumulation. Complementary computations (DFT/MEP) indicate robust electrostatic features and preferential stabilization in polar media, with the lowest relative energy in water. Together, these results establish YBL-1 as a water-bright, mitochondria-addressable fluorescent probe exhibiting selective Fe³⁺-responsive quenching suitable for live-cell imaging.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"250 ","pages":"Article 113644"},"PeriodicalIF":4.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146187414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel N-heterocyclic AIEgen for highly selective ATP sensing and visual bacterial detection in beverages","authors":"Wenlong Xing ,&nbsp;Yin Zhu ,&nbsp;Jiahao Wu ,&nbsp;Shijia Li ,&nbsp;Zhenyu Zhao ,&nbsp;Jinsong Zhang ,&nbsp;Shaowei Bo ,&nbsp;Ji Zeng ,&nbsp;Jiangling Peng","doi":"10.1016/j.dyepig.2026.113642","DOIUrl":"10.1016/j.dyepig.2026.113642","url":null,"abstract":"<div><div>The rapid and accurate detection of adenosine 5′-triphosphate (ATP) is crucial for clinical diagnostics, bioanalysis, and food safety. This study presents two novel aggregation-induced emission (AIE)-active probes, <strong>BIP-PP-1</strong> and <strong>BIP-PP-2</strong>, derived from a new N-heterocyclic AIEgen core, benzo[4,5]imidazo[1,2-<em>c</em>]pyrimidine (BIP). The optimized probe, <strong>BIP-PP-2</strong>, functions as a high-performance ATP sensor with a large Stokes shift, high sensitivity (LOD = 0.85 μM, linear range 0 – 90 μM), and excellent selectivity over structurally similar anions such as ADP, AMP, CTP, TTP, and UTP, a feature seldom achieved in small-molecule ATP probes. This unique selectivity is attributed to the novel BIP core, where specific π-π stacking and hydrogen-bonding interactions with the adenine moiety of ATP provide a superior stereoelectronic match, driving precise recognition and AIE-based fluorescence enhancement via a synergistic combination of electrostatic and non-covalent forces. <strong>BIP-PP-2</strong> was successfully applied in real-time ATP imaging within live bacterial cells and, notably, in the rapid visual detection of bacterial contamination in beverages using a portable 365 nm UV lamp, achieving a visual detection limit of 3.9 × 10⁵ CFU mL⁻¹ under ambient light. This work introduces the BIP scaffold as a promising platform for functional dye design and establishes <strong>BIP-PP-2</strong> as a robust analytical tool for on-site bioanalysis and food safety monitoring. © 2001 Elsevier Science. All rights reserved.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"250 ","pages":"Article 113642"},"PeriodicalIF":4.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146161974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent progress of Si-rhodamine-based probes in intracellular imaging of metal ions and small molecules","authors":"Yunjia Xu ,&nbsp;Xiaofei Tian ,&nbsp;Qi Ai ,&nbsp;Baoxiang Gao","doi":"10.1016/j.dyepig.2026.113643","DOIUrl":"10.1016/j.dyepig.2026.113643","url":null,"abstract":"<div><div>Si-rhodamines exhibit exceptional photostability and tunable near-infrared emission wavelengths, rendering them highly versatile tools for bioimaging applications—including cellular imaging, super-resolution imaging, in vivo imaging, and the detection of biological small molecules. Driven by the growing interest in Si-rhodamine-based probes and their significant potential for intracellular imaging of metal ions and small molecules, herein we systematically summarize the remarkable advancements in Si-rhodamine-derived fluorescent probes for this purpose. By elaborating on the design principles, reaction mechanisms, and biological applications of probes targeting a broad spectrum of analytes, encompassing metal ions (e.g., Mg²⁺, Ca²⁺, Cu⁺, Cu²⁺, Hg²⁺, Zn²⁺) and small molecules (e.g., HOCl, NO, formaldehyde, H₂S), we delineate how the superior photophysical properties of the Si-rhodamine scaffold underpin their robust performance in intracellular sensing. Furthermore, this review discusses key remaining challenges in the field and highlights promising future opportunities, providing valuable insights to guide subsequent research endeavors in the development of advanced Si-rhodamine-based imaging tools.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"250 ","pages":"Article 113643"},"PeriodicalIF":4.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146187412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanocoordinated Zn-Baicalein: Merging triple mechanisms with photothermal action for enhanced bacterial eradication","authors":"Xuemei Sun,&nbsp;Jiahao Li,&nbsp;Suyu Jiang,&nbsp;Lin Zang,&nbsp;Rong-Mei Kong,&nbsp;Yan Zhao,&nbsp;Weiheng Kong","doi":"10.1016/j.dyepig.2026.113641","DOIUrl":"10.1016/j.dyepig.2026.113641","url":null,"abstract":"<div><div>The escalating incidence of antibacterial resistance presents a formidable challenge in managing bacterial infections. Traditional Zn-based antibacterial agents face limitations due to their reliance on ultraviolet activation and potential neurotoxicity. The combination of nanotechnology and traditional Chinese medicine (TCM) not only reduces the side effects of Zn²⁺ but also enhances therapeutic efficacy. In this study, we synthesized Zn-baicalein nanoparticles (Zn-BE NPs) that self-assemble through chemical coordination, offering broad-spectrum antibacterial capabilities. The Zn component exhibited inherent antibacterial properties by disrupting the synthesis of bacterial metabolic enzymes and destroying genetic factors. Baicalein (BE), derived from <em>Scutellaria</em>, enhanced the NPs’ antibacterial efficacy by disrupting bacterial membranes and facilitating Zn²⁺ influx, leading to cell wall rupture and metabolic disruption. In addition, Zn-BE NPs exhibited excellent photothermal conversion efficiency, enabling effective bactericidal action under near-infrared irradiation. This triple synergistic mechanism not only overcame the limitations of conventional Zn-based therapies but also sustained long-term antibacterial activity by preventing rapid bacterial metabolism. Our findings demonstrated that Zn-BE NPs could achieve complete bacterial eradication, showcasing expected potential in addressing antibacterial resistance. This research laid a foundation for the development of safer and more effective antibacterial agents, with implications for future applications in combating resistant infections.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"250 ","pages":"Article 113641"},"PeriodicalIF":4.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146187413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pure-green top-emitting organic light-emitting diodes toward REC.2020 standard with ultra-narrow full-width at half-maximum","authors":"Yuhang Que ,&nbsp;Haoran Yang ,&nbsp;Guodong Sun ,&nbsp;Xiaoyang Xia ,&nbsp;Liang Zhou ,&nbsp;Li Wang","doi":"10.1016/j.dyepig.2026.113636","DOIUrl":"10.1016/j.dyepig.2026.113636","url":null,"abstract":"<div><div>Thermally activated delayed fluorescence (TADF) materials facilitate reverse intersystem crossing (RISC) by enhancing the intramolecular charge transfer (ICT) process, thereby increasing exciton utilization and significantly improving the efficiency of organic light-emitting diodes (OLEDs). However, the ICT process also results in considerable spectral broadening and diminished color purity in the devices. Here, a top-emission structure is employed to narrow the emission spectrum and improve the light extraction rate. The experimental results reveal that the full-width at half-maximum (FWHM) and color purity based on the first-order microcavity device are significantly optimized compared with the bottom-emitting organic light-emitting diodes (BE-OLEDs). The FWHM decreases from 93 to 33 nm with the external quantum efficiency (EQE) significantly increasing by 61%, indicating superior device efficiency. The FWHM of second-order microcavity devices is further reduced to 21 nm, achieving Commission Internationale de l'Eclairage coordinates of (0.164, 0.761), which is very close to the REC.2020 standard. Our strategy is simple and can significantly improve color purity of the prepared devices, which promotes the applications of OLEDs in high-gamut displays.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"250 ","pages":"Article 113636"},"PeriodicalIF":4.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146161975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-performance PM567-doped PMMA/E7 composites random lasers enabled by periodically patterned sapphire substrates for speckle-free imaging","authors":"Tianwei Song ,&nbsp;Jiarong Zhang ,&nbsp;Zihui Ran ,&nbsp;Caixia Xu ,&nbsp;Zhengguo Xiao ,&nbsp;Liu Wu ,&nbsp;Long Xu","doi":"10.1016/j.dyepig.2026.113638","DOIUrl":"10.1016/j.dyepig.2026.113638","url":null,"abstract":"<div><div>Dye-doped polymer liquid crystal (DD-PDLC) random lasers have exhibited promising potential in speckle-free laser imaging, non-polarized flexible displays, biological research, and optical sensing due to their unique features of low spatial coherence, multi-wavelength laser emission, and omnidirectional light output. However, challenges such as high lasing thresholds, poor film uniformity, and insufficient stability persist, primarily arising from fluorescence quenching and dye aggregation-induced gain reduction, photobleaching under prolonged excitation, and inadequate control over liquid crystal alignment and polymer network structures, which lead to unstable light scattering in pure liquid crystal systems. This study demonstrates a systematic optimization strategy for random lasers in PM567 doped poly (methyl methacrylate) (PMMA)/E7 liquid crystal composites, incorporating a patterned sapphire substrate (PSS) with periodic microstructures to enhance feedback efficiency, achieving a quality factor of 2846, a narrow linewidth of approximately 0.2 nm, and a remarkably low threshold of 0.52 mJ/cm². As a speckle-free random laser source, it exhibits a signal-to-noise ratio (SNR) of 23.37, showing a 16-fold improvement over pumped pulsed lasers (SNR = 1.41) and a 5-fold enhancement compared to white light sources (SNR = 4.57). These advancements have paved the way for the practical application of random lasers in high-resolution speckle-free bioimaging and next-generation optoelectronic devices.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"249 ","pages":"Article 113638"},"PeriodicalIF":4.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146184854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating fluorination effects in a perylene diimide trimer for organic solar cells","authors":"Yanjie Sun ,&nbsp;Yuheng Ni ,&nbsp;Ruize Zhou ,&nbsp;Zhenye Wang ,&nbsp;Xiang Gao ,&nbsp;Xiaoling Ma ,&nbsp;Jianhong Gao ,&nbsp;Hui Chen ,&nbsp;Fujun Zhang ,&nbsp;Zhitian Liu","doi":"10.1016/j.dyepig.2026.113621","DOIUrl":"10.1016/j.dyepig.2026.113621","url":null,"abstract":"<div><div>Three-dimensional (3D) perylene diimide (PDI) oligomers effectively suppress the excessive aggregation inherent to PDI monomers, yet their photovoltaic performance is often hampered by low electron mobility resulting from the distorted molecular structure. In this work, a new fluorinated PDI trimer (F-PDI3) was synthesized, alongside its non-fluorinated analogue (Ph-PDI) for comparative analysis. The F-PDI3 based device exhibited an electron mobility of 7.62 × 10⁻⁴ cm² V⁻¹ s⁻¹, which is 1.5 times higher than that of Ph-PDI based device (5.07 × 10⁻⁴ cm² V⁻¹ s⁻¹). This enhanced electron mobility, along with more favorable morphology contributed to enhanced charge generation and suppressed recombination. As a result, the PM6:F-PDI3 OSCs achieved a superior PCE value of 8.29 %, ranking among the top-performing PDI-based OSCs. This study demonstrates that fluorination as a potent strategy for enhancing the electron mobility of 3D PDI acceptor materials, thus improves their photovoltaic performance.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"249 ","pages":"Article 113621"},"PeriodicalIF":4.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design and application of β-gal fluorescent probes in cancer imaging: A review","authors":"Muhanad Alhujaily ,&nbsp;Alaa Shafie","doi":"10.1016/j.dyepig.2026.113608","DOIUrl":"10.1016/j.dyepig.2026.113608","url":null,"abstract":"<div><div>Beta-galactosidase (β-Gal) has emerged as a clinically relevant biomarker in oncology due to its elevated activity in multiple tumor types and its strong association with cellular senescence, lysosomal alterations, and therapy-induced stress responses. The ability to detect β-Gal activity with high sensitivity offers unique opportunities for early cancer diagnosis, real-time tumor visualization, and monitoring therapeutic outcomes. In recent years, fluorescent probes responsive to β-Gal have rapidly evolved as powerful molecular imaging tools, supported by advances in fluorophore engineering, enzyme-triggered activation strategies, and in vivo imaging technologies. These probes typically operate on mechanisms such as enzymatic cleavage of β-Gal, intramolecular charge transfer (ICT), aggregation-induced emission (AIE), photoinduced electron transfer (PET), excited-state intramolecular proton transfer (ESIPT) and near-infrared signaling platforms. Such designs allow high specificity, low background interference, deep-tissue penetration, and dynamic measurement of β-Gal activity in complex biological environments. This review provides a comprehensive overview of recent progress in the design and biomedical application of β-Gal-responsive fluorescent probes for cancer imaging. Key classes of fluorophores are discussed with regard to structural features, photophysical behavior, and responsiveness to enzymatic activation. Special emphasis is placed on innovations enabling turn-on, ratiometric, and two-photon imaging, as well as emerging strategies that leverage renal-clearable probes and activatable near-infrared (NIR) systems for tumor detection with high precision. Furthermore, the review highlights representative applications across cancer models, demonstrating the utility of β-Gal-activatable probes for distinguishing malignant from normal tissues, mapping tumor heterogeneity, visualizing senescent cancer cells, and evaluating therapeutic efficacy.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"249 ","pages":"Article 113608"},"PeriodicalIF":4.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146184851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual-state emission fluorescent probe based on 2,7-naphthyridine for visualization of third-level details in fingerprints","authors":"Yin-Si Sun ,&nbsp;Sai-Ping Geng ,&nbsp;Si-Jun Zhen ,&nbsp;Lv-Xi Qu ,&nbsp;Neng-Fang She","doi":"10.1016/j.dyepig.2026.113601","DOIUrl":"10.1016/j.dyepig.2026.113601","url":null,"abstract":"<div><div>Latent fingerprints (LFPs) play a crucial role in forensic identification. However, conventional detection methods often face challenges such as low contrast and toxicity. Existing fluorescent probes also have certain limitations, including aggregation-caused quenching (ACQ). The use of molecules exhibiting dual-state emission (DSE) properties offers a promising solution to these issues. In this study, we designed and synthesized three DSE fluorescent derivatives—<strong><em>NDTPA</em></strong>, <strong><em>NDSF</em></strong>, and <strong><em>NDPH</em></strong>—based on 2,7-naphthyridine and triphenylamine (TPA) to overcome these challenges. These derivatives exhibit excellent DSE properties. The introduction of diverse π-bridge structures effectively modulates their luminescence, thereby minimizing interference from complex background colors and ensuring optimal detection performance across various colored substrates. Using montmorillonite (MMT) as a matrix, composite powders (<strong><em>NDTPA-MMT</em></strong>, <strong><em>NDSF-MMT</em></strong>, and <strong><em>NDPH-MMT</em></strong>) were prepared for LFP imaging. These composites enable rapid and highly sensitive visualization of fingerprints on a wide range of substrates, including tin foil, glass, plastic, wood, coins, CD, ceramic and leather. They reveal features up to Level III (sweat pores) with exceptionally high contrast. In addition, the composite powders offer several advantages, including low cost, simple preparation, and convenient storage. These attributes present a promising strategy for high-resolution latent fingerprint detection and hold broad potential for forensic applications.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"249 ","pages":"Article 113601"},"PeriodicalIF":4.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A hypoxia-responsive prodrug for specific drug release and synergistic chemo-photodynamic cancer therapy","authors":"Zhen-Kun Sun ,&nbsp;Feng-Yan Yao ,&nbsp;Wen-Qiang Wu ,&nbsp;Yong-Jun Tao ,&nbsp;Tian-Jiao Gao ,&nbsp;Jian-Yong Liu ,&nbsp;Lijing Zheng","doi":"10.1016/j.dyepig.2026.113602","DOIUrl":"10.1016/j.dyepig.2026.113602","url":null,"abstract":"<div><div>Hypoxia within solid tumors significantly impairs the efficacy of photodynamic therapy (PDT), which relies on oxygen to generate cytotoxic reactive oxygen species (ROS). In this study, we turn this limitation into a therapeutic advantage by developing a hypoxia-activatable prodrug, BAP, which integrates a boron dipyrromethene (BODIPY)-based photosensitizer with paclitaxel (PTX) via a reductively cleavable azobenzene linker. Upon light irradiation, this photosensitizing prodrug mediates photodynamic action that consumes local oxygen, thereby aggravating tumor hypoxia. This heightened hypoxic state facilitates rapid cleavage of the azobenzene linker, resulting in the release of PTX specifically within tumors. As a consequence, tumor cells that survive PDT are effectively eliminated. Both in vitro and in vivo evaluations demonstrated the superior antitumor performance of BAP, which operates through a synergistic mechanism combining BODIPY-driven PDT and hypoxia-triggered chemotherapy. This study presents a novel strategy that not only addresses the challenge of hypoxia in PDT but also leverages it to achieve controlled combination therapy, offering a promising platform for synergistic cancer treatment.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"249 ","pages":"Article 113602"},"PeriodicalIF":4.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146090409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}