Dyes and Pigments最新文献

Alkoxy side-chain engineering of quinquethiophene-based fully non-fused ring acceptors with near-infrared absorption for efficient organic solar cells 高效有机太阳能电池中具有近红外吸收的五环埃塞俄比亚烯基全不熔环受体烷氧基侧链工程

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-06-11 DOI: 10.1016/j.dyepig.2025.112954

Siyuan Zang , Liying Dong , Jia Wang , Shuaiqi Wang , Xizhe Chu , Bofang Shan , Peng Yang , Zhigang Ni , Bin Kan , Qian Zhang

{"title":"Alkoxy side-chain engineering of quinquethiophene-based fully non-fused ring acceptors with near-infrared absorption for efficient organic solar cells","authors":"Siyuan Zang , Liying Dong , Jia Wang , Shuaiqi Wang , Xizhe Chu , Bofang Shan , Peng Yang , Zhigang Ni , Bin Kan , Qian Zhang","doi":"10.1016/j.dyepig.2025.112954","DOIUrl":"10.1016/j.dyepig.2025.112954","url":null,"abstract":"<div><div>Fully non-fused organic semiconductors with ultra-narrow bandgap offer exceptional potential for cost-effective organic photoelectric devices. Here, two quinquethiophene-based fully non-fused acceptors, 5T-OEH and 5T-2OEH, were designed and synthesized by varying the number of the alkoxy chain on the terminal thiophene. The inner alkoxy modified 5T-OEH adopts a more planar backbone and displays a redshifted absorption with an ultra-narrow optical bandgap of 1.29 eV compared to 5T-2OEH. After blending with donor D18, the 5T-OEH blend exhibits a preferential face-on molecular orientation, more compact intermolecular stacking and favorable phase separation. Consequently, organic solar cells (OSCs) based on 5T-OEH afforded a power conversion efficiency (PCE) of 12.64 %, surpassing those based on 5T-2OEH (7.44 %). This study underscores the effectiveness of alkoxy chain engineering in optimizing the performance of non-fused acceptors, providing a promising pathway for advancing low-cost and high-efficiency OSCs toward commercialization.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"242 ","pages":"Article 112954"},"PeriodicalIF":4.1,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144264022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultra-fast solvent-free access to organic long persistent luminescence materials via photopolymerization under mild conditions 在温和条件下通过光聚合获得有机长持久发光材料的超快速无溶剂途径

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-06-09 DOI: 10.1016/j.dyepig.2025.112956

Qingxin He, Tengyue Wang, Yue Zhang, Guangming Wang, Qianqian Yan, Kaka Zhang

{"title":"Ultra-fast solvent-free access to organic long persistent luminescence materials via photopolymerization under mild conditions","authors":"Qingxin He, Tengyue Wang, Yue Zhang, Guangming Wang, Qianqian Yan, Kaka Zhang","doi":"10.1016/j.dyepig.2025.112956","DOIUrl":"10.1016/j.dyepig.2025.112956","url":null,"abstract":"<div><div>Organic long persistent luminescence (OLPL) materials, which feature minutes or hours long afterglow durations and power-law emission decay profiles, have shown numerous potential applications, whereas the access to such materials usually relies on high-temperature melt-casting or time-consuming solvent evaporation. Here we report the fabrication of OLPL materials via photopolymerization of <em>N</em>-vinylcarbazole catalyzed by pyrylium salt. The polymerization is conducted at 80 °C (above the melting point of <em>N</em>-vinylcarbazole, 64 °C), which avoid the use of organic solvents and can be completed in 5 s. The resultant OLPL materials are p-type with charge recombination mechanism of hole transporting character, which are tolerate with ambient oxygen and exhibit power-law decay with afterglow intensity being proportional to t<sup>-m</sup> (m = 1.1–1.3). By incorporating a third component that is a red fluorescence dye into the photopolymerization system, the obtained three-component materials display red and enhanced OLPL property because of the excited state energy transfer from OLPL donor to fluorescence acceptor. The present study provides an ultra-fast and solvent-free method for OLPL materials, which pave the way for their wide-spread applications.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"242 ","pages":"Article 112956"},"PeriodicalIF":4.1,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144253399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Smartphone-assisted ratiometric fluorescence biosensor for mercury ion detection based on fluorescence-enhanced PCN-224 基于荧光增强PCN-224的智能手机辅助比例荧光生物传感器汞离子检测

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-06-09 DOI: 10.1016/j.dyepig.2025.112959

Meng Tian, Jiaxiong Li, Weiru Li, Zheng Liu, Rui Jin, Chunyan Sun, Junyang Wang

{"title":"Smartphone-assisted ratiometric fluorescence biosensor for mercury ion detection based on fluorescence-enhanced PCN-224","authors":"Meng Tian, Jiaxiong Li, Weiru Li, Zheng Liu, Rui Jin, Chunyan Sun, Junyang Wang","doi":"10.1016/j.dyepig.2025.112959","DOIUrl":"10.1016/j.dyepig.2025.112959","url":null,"abstract":"<div><div>Fluorescence-enhanced PCN-224 (FE-PCN-224) was prepared by modifying porphyrin MOF PCN-224 by 1 M Tris-HCl. We found that FE-PCN-224 was able to significantly enhance the fluorescence intensity of 6-FAM-labelled aptamer (FAM-Apt) in pure water, while its own fluorescence intensity was not disturbed. Based on the above, a ratiometric fluorescence biosensing platform was constructed relying on the specific recognition of Hg<sup>2+</sup> by T (thymine)-rich aptamers and the PET effect between T-Hg<sup>2+</sup>-T and FAM. The emission of FE-PCN-224 was used as the reference signal, and the emission of FAM-Apt was used as the sensitive response signal for detecting Hg<sup>2+</sup>. Hence, the concentration gradient of Hg<sup>2+</sup> could be accurately identified by the difference of the ratiometric signals <em>F</em><sub>518</sub>/<em>F</em><sub>650</sub>. The sensing system has good reliability and high stability. With the support of ImageJ software and mobile phone colour analysis software, convenient quantitative detection was realized through RGB channel analysis of real colour images. Meanwhile the prepared fluorescent colourimetric card can be applied to achieve semi-quantitative detection by the naked eye. The developed convenient biosensor provides a potential route for rapid detection of mercury ion contamination.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"242 ","pages":"Article 112959"},"PeriodicalIF":4.1,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144264020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multifunctional nanocomposite system with positing and Mn2+-enhanced-Cas12a shearing for precise and efficient intracellular imaging 具有定位和Mn2+增强cas12a剪切的多功能纳米复合系统，用于精确和高效的细胞内成像

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-06-09 DOI: 10.1016/j.dyepig.2025.112960

Haiping Tan , Jian Wei , Shengjuan Liu, Kejun Tan, Ruo Yuan, Shihong Chen

{"title":"Multifunctional nanocomposite system with positing and Mn2+-enhanced-Cas12a shearing for precise and efficient intracellular imaging","authors":"Haiping Tan , Jian Wei , Shengjuan Liu, Kejun Tan, Ruo Yuan, Shihong Chen","doi":"10.1016/j.dyepig.2025.112960","DOIUrl":"10.1016/j.dyepig.2025.112960","url":null,"abstract":"<div><div>The CRISPR/Cas12a fluorescence system is commonly used for in vitro detection, and its application in cells is challenging due to the difficulty in achieving precise localization and good reaction kinetics. This work creatively developed a multifunctional nanocomposite system (MNCS) with positing and Mn<sup>2+</sup>-enhanced-Cas12a shearing for precise and efficient intracellular imaging of microRNA-155 (miRNA-155). The rolling circle amplification (RCA) was well-engineered for generating a long single strand DNA (ssDNA), which was encoded with abundantly repetitive AS1411 aptamers for targeting cancer cells and functional sequences for activating Cas12a. This long ssDNA coupled MnO<sub>2</sub> nanoparticles (NPs), FAM and BHQ1 labeled reporter probes and CRISPR RNA/Cas12a (crRNA/Cas12a) to construct MNCS. AS1411 aptamers on ssDNA improved the targeting ability of MNCS, thereby reducing interference caused by mistargeted cells. As MNCS entered target cells, intracellular glutathione (GSH) converted MnO<sub>2</sub> into Mn<sup>2+</sup>, causing the disintegration of MNCS. In this case, the “lock-in state” crRNA hybridized with intracellular miRNA-155 to expose the binding site on crRNA so that it bound with functional sequences on ssDNA. Under the accelerated action of Mn<sup>2+</sup>, the <em>trans</em>-cleavage activity of Cas12a was highly activated for shearing reporter probes, thus recovering fluorescence signal of FAM. The MNCS with positing and Mn<sup>2+</sup>-enhanced-Cas12a shearing allowed in vitro detection of miRNA-155 with a low limit of detection of 4.67 pM, and also enabled highly sensitive intracellular imaging of miRNA-155. The coupling of targeting capability of AS1411 aptamers with significantly enhanced reaction kinetics of CRISPR/Cas12a system by Mn<sup>2+</sup> provides a promising intracellular imaging strategy for nucleic acid.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"242 ","pages":"Article 112960"},"PeriodicalIF":4.1,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144264018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Near-infrared emissive optical waveguides and photophysical insights based on 5H-[1,2,5]thiadiazolo[3,4-f]benzotriazole (BTD-BTZ) 基于5H-[1,2,5]噻二唑[3,4-f]苯并三唑（BTD-BTZ）的近红外发射光波导及其光物理研究

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-06-09 DOI: 10.1016/j.dyepig.2025.112949

Abelardo Sánchez-Oliva , Jesús Herrera Herreros , Abel de Cózar , Cristina Martín , M. Victoria Gomez , Pilar Prieto , Iván Torres-Moya

{"title":"Near-infrared emissive optical waveguides and photophysical insights based on 5H-[1,2,5]thiadiazolo[3,4-f]benzotriazole (BTD-BTZ)","authors":"Abelardo Sánchez-Oliva , Jesús Herrera Herreros , Abel de Cózar , Cristina Martín , M. Victoria Gomez , Pilar Prieto , Iván Torres-Moya","doi":"10.1016/j.dyepig.2025.112949","DOIUrl":"10.1016/j.dyepig.2025.112949","url":null,"abstract":"<div><div>In this work, a novel series of three 5<em>H</em>-[1,2,5]thiadiazolo[3,4-<em>f</em>]benzotriazole (<strong>BTD-BTZ</strong>) derivatives has been synthesized. The central core strategically combines benzothiadiazole (<strong>BTD</strong>) and benzotriazole (<strong>BTZ</strong>) moieties to achieve a red-shifted emission, resulting in fluorescence in near-infrared region (NIR). Additionally, these materials demonstrate promising optical waveguiding behavior in the NIR region with emission maxima higher than 800 nm for <strong>BTD-BTZ2</strong> and <strong>BTD-BTZ3</strong>, further highlighting their potential for advanced photonic applications. To the best of our knowledge, these are the first reported instances of <strong>BTD-BTZ</strong> derivatives exhibiting such waveguiding capabilities within this spectral range. A comprehensive photophysical characterization, including solvatochromism and halochromism studies, is presented, alongside a comparative analysis of the three synthesized derivatives. Theoretical calculations were also performed to support experimental results. The exceptional emission properties and NIR waveguiding behaviour underscores the potential of these <strong>BTD-BTZ</strong> derivatives for cutting-edge applications in telecommunications, bioimaging, and optical sensing.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"242 ","pages":"Article 112949"},"PeriodicalIF":4.1,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144253400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and structure study of coumarin 6 modified Zn-MOF and its application in artificial light capture system 香豆素6修饰Zn-MOF的合成、结构研究及其在人工光捕获系统中的应用

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-06-08 DOI: 10.1016/j.dyepig.2025.112953

Zi-Zhen Zhang, Ya-Fei Ma, Mei-Li Zhang, Yi-Xia Ren, Ji-Jiang Wang

{"title":"Synthesis and structure study of coumarin 6 modified Zn-MOF and its application in artificial light capture system","authors":"Zi-Zhen Zhang, Ya-Fei Ma, Mei-Li Zhang, Yi-Xia Ren, Ji-Jiang Wang","doi":"10.1016/j.dyepig.2025.112953","DOIUrl":"10.1016/j.dyepig.2025.112953","url":null,"abstract":"<div><div>With the recent advancements in materials science, solar energy as a kind of clean energy source has gained increasing importance, and the research in solar cell technology has become a prominent area. In particular, the development of photoelectric conversion materials has attracted significant attention. In this paper, a novel two-dimensional Zn-based metal-organic framework (Zn-MOF) with 4 × 4 grid wave layer structure was synthesized using flexible 1,3-phenyldiacetic acid (H<sub>2</sub>mpda) and rigid 3,5-bis (triazolium) pyridine (btyp) ligands. The fluorescence emission spectrum of Zn-MOF aligns with the UV–visible absorption spectrum of coumarin 6 (CM6), enabling their use as donor and acceptor for fluorescence resonance energy transfer (FRET) to construct an artificial light harvesting system (ALHS). Compared to Zn-MOF, Zn-MOF@CM6 demonstrates significantly larger surface area (7.4 m<sup>2</sup>/g), energy transfer efficiency (<em>Φ</em><sub><em>ET</em></sub>) of 47.7 %, and photocurrent on/off ratio (<em>I</em><sub><em>light</em></sub><em>/I</em><sub><em>dark</em></sub>) of 50:1, which far exceeds previously reported values in literature. Interestingly, during the battery charge and discharge test, the diode of Zn-MOF@CM6 was observed to emit light. Zn-MOF@CM6 not only expands the application of MOF materials in artificial light harvesting systems, but also provides a new perspective for solar energy utilization and solar cell construction.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"242 ","pages":"Article 112953"},"PeriodicalIF":4.1,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144264021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Origin of abnormal fluorescence in organometallic complexes: Weak heavy-atom effect and large energy gap 金属有机配合物中异常荧光的来源：弱重原子效应和大能隙

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-06-08 DOI: 10.1016/j.dyepig.2025.112945

Kaiqi Lv , Anqi Lv , Yufeng Mao , Yongyang Zhang , Huili Ma

{"title":"Origin of abnormal fluorescence in organometallic complexes: Weak heavy-atom effect and large energy gap","authors":"Kaiqi Lv , Anqi Lv , Yufeng Mao , Yongyang Zhang , Huili Ma","doi":"10.1016/j.dyepig.2025.112945","DOIUrl":"10.1016/j.dyepig.2025.112945","url":null,"abstract":"<div><div>Organometallic complexes typically exhibit phosphorescence, which originate from the heavy-atom effect (HAE) that facilitates spin-forbidden transitions via enhanced spin–orbit coupling (SOC). However, certain complexes display anomalous fluorescence, challenging conventional understanding. Here, we investigated two representative fluorescent organometallic complexes, <strong>Per-B-Au</strong> and <strong>PMI-Pt</strong>, using time-dependent density functional theory coupled with the thermal vibration correlation function method. Our results demonstrate that the abnormal fluorescence originates from the weakened HAE and large energy gap. In <strong>Per-B-Au</strong>, the presence of bridging unit decouples the chromophore from the metal center, effectively suppressing SOC and thereby reducing the ISC rate. In contrast, <strong>PMI-Pt</strong> exhibits moderate SOC enhancement due to covalent bonding between Pt atom and chromophore. Nevertheless, the ISC rate (∼10<sup>7</sup> s<sup>−1</sup>) in <strong>PMI-Pt</strong> remains lower than the radiative decay rate (<em>k</em><sub>f</sub> ∼10<sup>8</sup> s<sup>−1</sup>), which is attributed to the distinct excited-state features of the chromophore, including a large oscillator strength, an energetically lower S<sub>1</sub> relative to T<sub>2</sub>, and a large singlet-triplet energy gap (Δ<em>E</em><sub>ST</sub>). Our proposed mechanism is also tenable for other reported fluorescent organometallic complexes. These findings provide fundamental insights into the luminescence mechanisms in organometallics and offer valuable guidance for designing novel fluorescent materials.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"242 ","pages":"Article 112945"},"PeriodicalIF":4.1,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144242793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and investigation of easily modifiable nicotinonitrile-based building blocks for organic donor-acceptor chromophores 易修饰的烟腈基有机给受体发色团的合成与研究

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-06-06 DOI: 10.1016/j.dyepig.2025.112929

Ivan N. Bardasov, Ekaterina N. Ramskaya, Anastasiya U. Alekseeva, Mikhail Yu. Ievlev

{"title":"Synthesis and investigation of easily modifiable nicotinonitrile-based building blocks for organic donor-acceptor chromophores","authors":"Ivan N. Bardasov, Ekaterina N. Ramskaya, Anastasiya U. Alekseeva, Mikhail Yu. Ievlev","doi":"10.1016/j.dyepig.2025.112929","DOIUrl":"10.1016/j.dyepig.2025.112929","url":null,"abstract":"<div><div>Convenient methods for synthesizing two isomeric nicotinonitrile-based building blocks with 2-amino-4-aryl- and 4-amino-2-arylpyridine-3,5-dicarbonitrile moieties were developed. These blocks were modified at the C6 position using <em>N-</em>, <em>O-</em>, or <em>C</em>-nucleophiles. The investigation of the effect of solvents on the spectral and luminescent properties of the synthesized chromophores revealed that the emission characteristics of 2-aryl derivatives are more significantly influenced by the polarity of the solvent, while 4-aryl-substituted molecules are primarily affected by acidity. The absorption and emission maxima of the starting 4-aryl- and 2-aryl-6-chloropyridines were observed at lower energy wavelengths than those of the <em>N-</em>, <em>O-</em>, and <em>C-</em>substituted derivatives. Chemosensory studies showed that the emission intensity of 6-amino-2-(dicyanomethylene)-4-(4-(dimethylamino)phenyl)-1,2-dihydropyridine-3,5-dicarbonitrile increased significantly in the presence of Ag<sup>+</sup> ions in aqueous solution.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"242 ","pages":"Article 112929"},"PeriodicalIF":4.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144243224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Decoding the heavy atom effect and Spin–orbit coupling in D-A Molecules: Synergy or Antagonism in facilitating intersystem crossing 解码D-A分子中的重原子效应和自旋轨道耦合：促进系统间交叉的协同或拮抗作用

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-06-06 DOI: 10.1016/j.dyepig.2025.112951

Xiaoying Hao , Wenbi Feng , Ying Tang , Xueluer Mu , Yongxian Zhao , Yingxi Lu , Xianfeng Zhou

{"title":"Decoding the heavy atom effect and Spin–orbit coupling in D-A Molecules: Synergy or Antagonism in facilitating intersystem crossing","authors":"Xiaoying Hao , Wenbi Feng , Ying Tang , Xueluer Mu , Yongxian Zhao , Yingxi Lu , Xianfeng Zhou","doi":"10.1016/j.dyepig.2025.112951","DOIUrl":"10.1016/j.dyepig.2025.112951","url":null,"abstract":"<div><div>Intersystem crossing (ISC) of triple photosensitizers (PSs) often hinges on enhanced spin−orbit coupling (SOC), typically achieved by incorporating heavy atoms or designing orthogonal donor-acceptor (D-A) dyads. Herein, we explore the synergistic potential of both strategies by integrating a heavy atom and an orthogonal D-A structure within a single PS framework. Specifically, orthogonal heptamethine cyanine (OrT-Cy7-H) is halogenated to yield OrT-Cy7-Cl and OrT-Cy7-Br via molecular engineering. Through theoretical calculations and time-resolved spectroscopy, the ISC of OrT-Cy7-Br is confirmed to be derived from the bromine substitution and the nearly orthogonal D-A structure. Interestingly, the incorporation of bromine enhances molecular aggregation and promotes non-radiative decay through intermolecular collisions. When formulated into nanoparticles, OrT-Cy7-Br exhibits efficient combined photodynamic and photothermal therapeutic effects, underscoring the critical role of both molecular structure and intermolecular interactions in shaping the photophysical properties of PSs. These findings offer valuable insights into the design of next-generation PSs for advanced cancer therapy.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"242 ","pages":"Article 112951"},"PeriodicalIF":4.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144229636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

De novo design of ratiometric near-infrared probe revealing phase transition of mitochondrial inner membrane during ferroptosis and autophagy 比率近红外探针的从头设计，揭示铁下垂和自噬过程中线粒体内膜的相变

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-06-06 DOI: 10.1016/j.dyepig.2025.112948

Chenyu Shi , Zhiyuan Wang , Qingqing Lu , Minggang Tian

{"title":"De novo design of ratiometric near-infrared probe revealing phase transition of mitochondrial inner membrane during ferroptosis and autophagy","authors":"Chenyu Shi , Zhiyuan Wang , Qingqing Lu , Minggang Tian","doi":"10.1016/j.dyepig.2025.112948","DOIUrl":"10.1016/j.dyepig.2025.112948","url":null,"abstract":"<div><div>The liquid ordered (L<sub>o</sub>) and liquid disordered (L<sub>d</sub>) phase microdomains in mitochondrial inner membranes play indispensable yet different roles in vital bioactivities including metabolism, signaling, and apoptosis. Therefore, discriminatively visualizing L<sub>o</sub> and L<sub>d</sub> phases in mitochondrial membranes is an urgent task for fundamental biology and pathology. However, fluorescent probes for ratiometric visualization of the membrane phases in mitochondria are rarely reported. Herein, we have constructed a dual-emissive fluorogen highly sensitive to environmental polarity by regulating the electron donor and acceptor, and de novo designed a fluorescent probe (<strong>MT-phs</strong>) for the separate and ratiometric visualization of L<sub>o</sub> and L<sub>d</sub> microdomains in mitochondrial inner membranes. Model membrane and lipids treatment experiments proved that <strong>MT-phs</strong> enabled the discrimination of L<sub>o</sub> and L<sub>d</sub> phase in ratiometric manner. With the newly designed probe, the increased L<sub>d</sub> domains and fluidity in mitochondrial inner membranes during ferroptosis and starvation stimuli has been revealed. The phase transition in mitochondria were also in-situ and real-timely monitored successfully.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"242 ","pages":"Article 112948"},"PeriodicalIF":4.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144242790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0