Small Science最新文献_第8页

Surface Modification of Mesoporous Silica Nanoparticles as a Means to Introduce Inherent Cancer-Targeting Ability in a 3D Tumor Microenvironment 介孔二氧化硅纳米粒子的表面改性是在三维肿瘤微环境中引入固有癌症靶向能力的一种手段

IF 12.7

Small Science Pub Date : 2024-07-08 DOI: 10.1002/smsc.202400084

Neeraj Prabhakar, Erica Långbacka, Ezgi Özliseli, Jesse Mattsson, Alaa Mahran, Ilida Suleymanova, Cecilia Sahlgren, Jessica M. Rosenholm, Malin Åkerfelt, Matthias Nees

{"title":"Surface Modification of Mesoporous Silica Nanoparticles as a Means to Introduce Inherent Cancer-Targeting Ability in a 3D Tumor Microenvironment","authors":"Neeraj Prabhakar, Erica Långbacka, Ezgi Özliseli, Jesse Mattsson, Alaa Mahran, Ilida Suleymanova, Cecilia Sahlgren, Jessica M. Rosenholm, Malin Åkerfelt, Matthias Nees","doi":"10.1002/smsc.202400084","DOIUrl":"https://doi.org/10.1002/smsc.202400084","url":null,"abstract":"Mesoporous silica nanoparticles (MSNs) have emerged as promising drug carriers that can facilitate targeted anticancer drug delivery, but efficiency studies relying on active targeting mechanisms remain elusive. This study implements in vitro 3D cocultures, so-called microtissues, to model a physiologically relevant tumor microenvironment (TME) to examine the impact of surface-modified MSNs without targeting ligands on the internalization, cargo delivery, and cargo release in tumor cells and cancer-associated fibroblasts. Among these, acetylated MSNs most effectively localized in tumor cells in a 3D setting containing collagen, while other MSNs did so to a lesser degree, most likely due to remaining trapped in the extracellular matrix of the TME. Confocal imaging of hydrophobic model drug-loaded MSNs demonstrated effective cargo release predominantly in tumor cells, both in 2D and 3D cocultures. MSN-mediated delivery of an anticancer drug in the microtissues exhibited a significant reduction in tumor organoid size and enhanced the tumor-specific cytotoxic effects of a γ-secretase inhibitor, compared to the highly hydrophobic drug in free form. This inherent targeting potential suggests reduced off-target effects and increased drug efficacy, showcasing the promise of surface modification of MSNs as a means of direct cell-specific targeting and delivery for precise and successful targeted drug delivery.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":null,"pages":null},"PeriodicalIF":12.7,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141612596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive Understanding of Elemental Doping and Substitution of Ni-Rich Cathode Materials for Lithium-Ion Batteries via In Situ Operando Analyses 通过原位操作分析全面了解锂离子电池富镍阴极材料的元素掺杂和替代情况

IF 12.7

Small Science Pub Date : 2024-07-08 DOI: 10.1002/smsc.202400165

Yun Seong Byeon, Wontae Lee, Sangbin Park, Dongil Kim, Jaewoo Jung, Min-Sik Park, Won-Sub Yoon

{"title":"Comprehensive Understanding of Elemental Doping and Substitution of Ni-Rich Cathode Materials for Lithium-Ion Batteries via In Situ Operando Analyses","authors":"Yun Seong Byeon, Wontae Lee, Sangbin Park, Dongil Kim, Jaewoo Jung, Min-Sik Park, Won-Sub Yoon","doi":"10.1002/smsc.202400165","DOIUrl":"https://doi.org/10.1002/smsc.202400165","url":null,"abstract":"This review explores the challenges and advancements in the development of high-energy lithium-ion batteries (LIBs), particularly focusing on the electrochemical and structural stability of Ni-rich cathode materials. Despite their potential to increase the energy density of LIBs, these cathode materials encounter issues such as irreversible phase transitions and structural degradation during cycling, which ultimately affect their electrochemical performance. Elemental doping/substitution has emerged as promising strategies to address these challenges. However, the precise mechanisms underlying their performance enhancement remain unclear. The objective is to elucidate the complex reaction mechanisms triggered by doping and substitution in Ni-rich cathode materials by employing in situ operando analyses to uncover their effects on electrochemical behavior and structural integrity during cycling. This comprehensive investigation aims to clarify the roles of elemental dopants or substituents in the crystal structures of Ni-rich cathode materials, thereby offering valuable insights for the structural engineering of cathode materials in high-energy LIBs. By elucidating these intricate mechanisms, this review provides a practical roadmap for future research and significantly contributes to LIB technology by guiding material design and optimization strategies in the development of advanced LIBs.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":null,"pages":null},"PeriodicalIF":12.7,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141572416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gut Microbiota Regulate Saturated Free Fatty Acid Metabolism in Heart Failure 肠道微生物群调节心力衰竭患者的饱和游离脂肪酸代谢

IF 12.7

Small Science Pub Date : 2024-07-08 DOI: 10.1002/smsc.202300337

Gulinigaer Tuerhongjiang, Manyun Guo, Xiangrui Qiao, Junhui Liu, Wen Xi, Yuanyuan Wei, Peining Liu, Bowen Lou, Chen Wang, Lizhe Sun, Xiao Yuan, Hui Liu, Ying Xiong, Yunlong Ma, Hongbing Li, Bo Zhou, Lijuan Li, Zuyi Yuan, Yue Wu, Jianqing She

{"title":"Gut Microbiota Regulate Saturated Free Fatty Acid Metabolism in Heart Failure","authors":"Gulinigaer Tuerhongjiang, Manyun Guo, Xiangrui Qiao, Junhui Liu, Wen Xi, Yuanyuan Wei, Peining Liu, Bowen Lou, Chen Wang, Lizhe Sun, Xiao Yuan, Hui Liu, Ying Xiong, Yunlong Ma, Hongbing Li, Bo Zhou, Lijuan Li, Zuyi Yuan, Yue Wu, Jianqing She","doi":"10.1002/smsc.202300337","DOIUrl":"https://doi.org/10.1002/smsc.202300337","url":null,"abstract":"Aims: Heart failure (HF) is associated with profound changes in cardiac metabolism. At present, there is still a lack of relevant research to explore the key microbiome and their metabolites affecting the progression of HF. Herein, the interaction of gut microbiota and circulating free fatty acid (FFA) in HF patients and mice is investigated. Methods and Results: In HF patients, by applying metagenomics analysis and targeted FFA metabolomics, enriched abundance of Clostridium sporogenes (C.sp) in early and late stage of HF patients, which negatively correlated to saturated free fatty acid (SFA) levels, is identified. KEGG analysis further indicates microbiota gene enrichment in FFA degradation in early HF, and decreased gene expression in FFA synthesis in late HF. In HF mice (C57BL/6J) induced by isoproterenol (ISO), impaired intestinal permeability is observed, and decreased fecal C.sp and increased SFA are further validated. At last, by supplementing C.sp to ISO-induced HF mice, the cardiac function, fibrosis, and myocardial size are partially rescued, together with decreased circulating SFA levels. Conclusions: Clostridium abundance is increased in HF, compensating cardiac function deterioration via downregulation of circulating SFA levels. The results demonstrate that the gut microbiota–SFA axis plays an important role in HF protection, which may provide a strategic advantage for the probiotic therapy development in HF.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":null,"pages":null},"PeriodicalIF":12.7,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141572415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Glance into the Near Future: Cultivated Meat from Mammalian and Insect Cells 未来一瞥：利用哺乳动物和昆虫细胞培养肉类

IF 12.7

Small Science Pub Date : 2024-07-08 DOI: 10.1002/smsc.202400122

Fabiana Giglio, Carmen Scieuzo, Sofia Ouazri, Valentina Pucciarelli, Dolores Ianniciello, Sophia Letcher, Rosanna Salvia, Ambrogio Laginestra, David L. Kaplan, Patrizia Falabella

{"title":"A Glance into the Near Future: Cultivated Meat from Mammalian and Insect Cells","authors":"Fabiana Giglio, Carmen Scieuzo, Sofia Ouazri, Valentina Pucciarelli, Dolores Ianniciello, Sophia Letcher, Rosanna Salvia, Ambrogio Laginestra, David L. Kaplan, Patrizia Falabella","doi":"10.1002/smsc.202400122","DOIUrl":"https://doi.org/10.1002/smsc.202400122","url":null,"abstract":"The increasing global population and demand for meat have led to the need to find sustainable and viable alternatives to traditional production methods. One potential solution is cultivated meat (CM), which involves producing meat in vitro from animal stem cells to generate products with nutritional and sensory properties similar to conventional livestock-derived meat. This article examines current approaches to CM production and investigates how using insect cells could enhance the process. Cell sources are a critical issue in CM production, alongside advances in culture media, bioreactors for scalability, and scaffold development. Insect cells, compared to commonly used mammalian cells, may offer advantages in overcoming technological challenges that hinder cell culture development and expansion. The objective of this review is to emphasize how insects, as a cell source for CM production, could offer a more sustainable option. A crucial aspect for achieving this goal is a comprehensive understanding of the physiology of muscle and fat cells. In this work, the characteristics of insect and mammalian cells are compared, focusing particularly on muscle and fat cell development, regulatory pathways, hormonal regulation, and tissue composition. Insect cells are a promising source for CM, offering a sustainable and environmentally friendly alternative.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":null,"pages":null},"PeriodicalIF":12.7,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141577694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Zero-Dimensional Interstitial Electron-Induced Spin–Orbit Coupling Dirac States in Sandwich Electride 夹层氢化物中零维间隙电子诱导的自旋轨道耦合狄拉克态

IF 12.7

Small Science Pub Date : 2024-07-05 DOI: 10.1002/smsc.202400131

Weizhen Meng, Jiayu Jiang, Yalong Jiao, Fengxian Ma, Ying Yang, Zhenxiang Cheng, Xiaotian Wang

{"title":"Zero-Dimensional Interstitial Electron-Induced Spin–Orbit Coupling Dirac States in Sandwich Electride","authors":"Weizhen Meng, Jiayu Jiang, Yalong Jiao, Fengxian Ma, Ying Yang, Zhenxiang Cheng, Xiaotian Wang","doi":"10.1002/smsc.202400131","DOIUrl":"https://doi.org/10.1002/smsc.202400131","url":null,"abstract":"The development of inorganic electrides offers new possibilities for studying topological states due to the nonnuclear-binding properties displayed by interstitial electrons. Herein, a sandwich electride 2[CaCl]+:2e− is designed, featuring a tetragonal lattice structure, including two atomic lattice layers and one interstitial electron layer. The interstitial electrons form nonsymmorphic-symmetry-protected Dirac points (DPs) at the X and M points, which are robust against the spin–orbit coupling effect. DPs exhibit an approximately elliptical shape, characterized by a relatively high anisotropy, resulting from the interplay between the electron and atomic layers. In addition, 2[CaCl]+:2e− possesses a lower work function (WF) (3.43 eV), endowing it with robust electron-supplying characteristics. Due to the low WF and interstitial electrons, 2[CaCl]+:2e− loaded Ru shows outstanding catalytic performance for N2 cleavage. A potential research platform for exploring the formation of topological states and promoting nitrogen cracking in electrides is provided.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":null,"pages":null},"PeriodicalIF":12.7,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141547914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magnetoionics for Synaptic Devices and Neuromorphic Computing: Recent Advances, Challenges, and Future Perspectives 用于突触设备和神经形态计算的磁场学：最新进展、挑战和未来展望

IF 12.7

Small Science Pub Date : 2024-07-04 DOI: 10.1002/smsc.202400133

P. Monalisha, Maria Ameziane, Irena Spasojevic, Eva Pellicer, Rhodri Mansell, Enric Menéndez, Sebastiaan van Dijken, Jordi Sort

{"title":"Magnetoionics for Synaptic Devices and Neuromorphic Computing: Recent Advances, Challenges, and Future Perspectives","authors":"P. Monalisha, Maria Ameziane, Irena Spasojevic, Eva Pellicer, Rhodri Mansell, Enric Menéndez, Sebastiaan van Dijken, Jordi Sort","doi":"10.1002/smsc.202400133","DOIUrl":"https://doi.org/10.1002/smsc.202400133","url":null,"abstract":"With the advent of Big Data, traditional digital computing is struggling to cope with intricate tasks related to data classification or pattern recognition. To mitigate this limitation, software-based neural networks are implemented, but they are run in conventional computers whose operation principle (with separate memory and data-processing units) is highly inefficient compared to the human brain. Brain-inspired in-memory computing is achieved through a wide variety of methods, for example, artificial synapses, spiking neural networks, or reservoir computing. However, most of these methods use materials (e.g., memristor arrays, spintronics, phase change memories) operated with electric currents, resulting in significant Joule heating effect. Tuning magnetic properties by voltage-driven ion motion (i.e., magnetoionics) has recently emerged as an alternative energy-efficient approach to emulate functionalities of biological synapses: potentiation/depression, multilevel storage, or transitions from short-term to long-term plasticity. In this perspective, the use of magnetoionics in neuromorphic applications is critically reviewed, with emphasis on modulating synaptic weight through: 1) control of magnetization by voltage-induced ion retrieval/insertion; and 2) control of magnetic stripe domains and skyrmions in gated magnetic thin films adjacent to solid-state ionic supercapacitors. The potential prospects in this emerging research area together with a forward-looking discussion on future opportunities are provided.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":null,"pages":null},"PeriodicalIF":12.7,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141547913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Highly Charged Positive Cage Causes Simultaneous Enhancement of Type-II and O2-Independent-Type-I Photodynamic Therapy via One-/Two-Photon Stimulation and Tumor Immunotherapy via PANoptosis and Ferroptosis 高电荷正笼子通过单/双光子刺激和泛凋亡与铁凋亡同时增强 II 型和 O2 依赖性 I 型光动力疗法和肿瘤免疫疗法

IF 12.7

Small Science Pub Date : 2024-07-04 DOI: 10.1002/smsc.202400220

Xiao-Dong Zhang, Hui-Juan Yu, Shao-Qi Guan, Yu-Lin Lu, Yu Zhang, Yin-Hui Huang, Ya-Ping Wang, Chen-Hui Liu, Zhong-Min Cao, Yu-Han Qin, Mei Pan, Jun Shen, Cheng-Yong Su

{"title":"A Highly Charged Positive Cage Causes Simultaneous Enhancement of Type-II and O2-Independent-Type-I Photodynamic Therapy via One-/Two-Photon Stimulation and Tumor Immunotherapy via PANoptosis and Ferroptosis","authors":"Xiao-Dong Zhang, Hui-Juan Yu, Shao-Qi Guan, Yu-Lin Lu, Yu Zhang, Yin-Hui Huang, Ya-Ping Wang, Chen-Hui Liu, Zhong-Min Cao, Yu-Han Qin, Mei Pan, Jun Shen, Cheng-Yong Su","doi":"10.1002/smsc.202400220","DOIUrl":"https://doi.org/10.1002/smsc.202400220","url":null,"abstract":"To solve the oxygen dependence problem of photodynamic therapy (PDT), it is critical to explore photosensitizers that do not rely on O2 molecule to generate reactive oxygen species (ROS). Herein, a stable cationic metal-organic cage [Pd6(RuLoz3)8](BF4)28 (MOC-88) that possesses high +28 charges is designed. The cage-confined positive microenvironment enables efficient generation of hydroxyl radicals and improved yield of the singlet oxygen under one-/two-photon excitation, showing excellent performance to concurrently enhance Type-II and O2-independent-Type-I PDT. Moreover, the effective ROS production and robust lipid peroxidation trigger a series of signaling pathways (inflammasome, cyclic guanosine monophosphate–adenosine monophosphate synthase stimulator of interferon genes, and NF-κB) to evoke PANoptosis and ferroptosis in tumor cells, enabling MOC-88 to simultaneously cause the loss of cell membrane integrity, release a series of inflammatory cytokines and damage-associated molecular patterns, stimulate the maturation and antigen presentation ability of dendritic cells, and ultimately activate T-cell-dependent adaptive immunity in vivo to inhibit tumor growth.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":null,"pages":null},"PeriodicalIF":12.7,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141547912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emergent Antiferroelectric Ordering and the Coupling of Liquid Crystalline and Polar Order 新出现的反铁电有序以及液晶有序和极性有序的耦合

IF 12.7

Small Science Pub Date : 2024-07-03 DOI: 10.1002/smsc.202400189

Jordan Hobbs, Calum J. Gibb, Richard J. Mandle

引用次数: 0

A Novel Piezo1 Agonist Promoting Mesenchymal Stem Cell Proliferation and Osteogenesis to Attenuate Disuse Osteoporosis 一种促进间充质干细胞增殖和骨生成的新型 Piezo1 激动剂，可减轻废用性骨质疏松症

IF 12.7

Small Science Pub Date : 2024-06-30 DOI: 10.1002/smsc.202400061

Ruihan Hao, Hairong Tang, Chunyong Ding, Bhavana Rajbanshi, Yuhang Liu, Ding Ma, Zhouyi Duan, Yuxin Qi, Liming Dai, Bingjun Zhang, Ao Zhang, Xiaoling Zhang

{"title":"A Novel Piezo1 Agonist Promoting Mesenchymal Stem Cell Proliferation and Osteogenesis to Attenuate Disuse Osteoporosis","authors":"Ruihan Hao, Hairong Tang, Chunyong Ding, Bhavana Rajbanshi, Yuhang Liu, Ding Ma, Zhouyi Duan, Yuxin Qi, Liming Dai, Bingjun Zhang, Ao Zhang, Xiaoling Zhang","doi":"10.1002/smsc.202400061","DOIUrl":"https://doi.org/10.1002/smsc.202400061","url":null,"abstract":"Disuse osteoporosis (OP) is a state of bone loss due to lack of mechanical stimuli, probably induced by prolonged bed rest, neurological diseases, as well as microgravity. Currently the precise treatment strategies of disuse OP remain largely unexplored. Piezo1, a mechanosensitive calcium (Ca2+) ion channel, is a key force sensor mediating mechanotransduction and it is demonstrated to regulate bone homeostasis and osteogenesis in response to mechanical forces. Using structure-based drug design, a novel small-molecule Piezo1 agonist, MCB-22-174, which can effectively activate Piezo1 and initiate Ca2+ influx, is developed and is more potent than the canonical Piezo1 agonist, Yoda1. Moreover, MCB-22-174 is found as a safe Piezo1 agonist without any signs of serious toxicity. Mechanistically, Piezo1 activation promotes the proliferation of bone marrow mesenchymal stem cells by activating the Ca2+-related extracellular signal-related kinases and calcium–calmodulin (CaM)-dependent protein kinase II (CaMKII) pathway. Importantly, MCB-22-174 could effectively promote osteogenesis and attenuate disuse OP in vivo. Overall, the findings provide a promising therapeutic strategy for disuse OP by chemical activation of Piezo1.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":null,"pages":null},"PeriodicalIF":12.7,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141527483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Body-Integrated Ultrasensitive All-Textile Pressure Sensors for Skin-Inspired Artificial Sensory Systems 用于皮肤启发式人工感觉系统的人体集成超敏感全织物压力传感器

IF 12.7

Small Science Pub Date : 2024-06-30 DOI: 10.1002/smsc.202400026

Bingjun Wang, Yuanhong Shi, Haotian Li, Qilin Hua, Keyu Ji, Zilong Dong, Zhaowei Cui, Tianci Huang, Zhongming Chen, Ruilai Wei, Weiguo Hu, Guozhen Shen

{"title":"Body-Integrated Ultrasensitive All-Textile Pressure Sensors for Skin-Inspired Artificial Sensory Systems","authors":"Bingjun Wang, Yuanhong Shi, Haotian Li, Qilin Hua, Keyu Ji, Zilong Dong, Zhaowei Cui, Tianci Huang, Zhongming Chen, Ruilai Wei, Weiguo Hu, Guozhen Shen","doi":"10.1002/smsc.202400026","DOIUrl":"https://doi.org/10.1002/smsc.202400026","url":null,"abstract":"Tactile sensing plays a vital role in human somatosensory perception as it provides essential touch information necessary for interacting with the environment and accomplishing daily tasks. The progress in textile electronics has opened up opportunities for developing intelligent wearable devices that enable somatosensory perception and interaction. Herein, a skin-inspired all-textile pressure sensor (ATP) is presented that emulates the sensing and interaction functions of human skin, offering wearability, comfort, and breathability. The ATP demonstrates impressive features, including ultrahigh sensitivity (1.46 × 106 kPa−1), fast response time (1 ms), excellent stability and durability (over 2000 compression-release cycles), a low detection limit of 10 Pa, and remarkable breathability (93.2%). The multipixel array of ATPs has been proven to facilitate static and dynamic mapping of spatial pressure, as well as pressure trajectory monitoring functions. Moreover, by integrating ATP with oscillation circuits, external force stimuli can be directly encoded into digital frequency pulses that resemble human physiological signals. The frequency of output pulses increases with the applied pressure. Consequently, an ATP-based artificial sensory system is constructed for intelligent tactile perception. This work provides a simple and versatile strategy for practical applications of wearable electronics in the fields of robotics, sports science, and human–machine interfaces technologies.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":null,"pages":null},"PeriodicalIF":12.7,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141527482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0