Small SciencePub Date : 2024-07-08DOI: 10.1002/smsc.202400165
Yun Seong Byeon, Wontae Lee, Sangbin Park, Dongil Kim, Jaewoo Jung, Min-Sik Park, Won-Sub Yoon
{"title":"Comprehensive Understanding of Elemental Doping and Substitution of Ni-Rich Cathode Materials for Lithium-Ion Batteries via In Situ Operando Analyses","authors":"Yun Seong Byeon, Wontae Lee, Sangbin Park, Dongil Kim, Jaewoo Jung, Min-Sik Park, Won-Sub Yoon","doi":"10.1002/smsc.202400165","DOIUrl":"https://doi.org/10.1002/smsc.202400165","url":null,"abstract":"This review explores the challenges and advancements in the development of high-energy lithium-ion batteries (LIBs), particularly focusing on the electrochemical and structural stability of Ni-rich cathode materials. Despite their potential to increase the energy density of LIBs, these cathode materials encounter issues such as irreversible phase transitions and structural degradation during cycling, which ultimately affect their electrochemical performance. Elemental doping/substitution has emerged as promising strategies to address these challenges. However, the precise mechanisms underlying their performance enhancement remain unclear. The objective is to elucidate the complex reaction mechanisms triggered by doping and substitution in Ni-rich cathode materials by employing in situ operando analyses to uncover their effects on electrochemical behavior and structural integrity during cycling. This comprehensive investigation aims to clarify the roles of elemental dopants or substituents in the crystal structures of Ni-rich cathode materials, thereby offering valuable insights for the structural engineering of cathode materials in high-energy LIBs. By elucidating these intricate mechanisms, this review provides a practical roadmap for future research and significantly contributes to LIB technology by guiding material design and optimization strategies in the development of advanced LIBs.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"29 1","pages":""},"PeriodicalIF":12.7,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141572416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gut Microbiota Regulate Saturated Free Fatty Acid Metabolism in Heart Failure","authors":"Gulinigaer Tuerhongjiang, Manyun Guo, Xiangrui Qiao, Junhui Liu, Wen Xi, Yuanyuan Wei, Peining Liu, Bowen Lou, Chen Wang, Lizhe Sun, Xiao Yuan, Hui Liu, Ying Xiong, Yunlong Ma, Hongbing Li, Bo Zhou, Lijuan Li, Zuyi Yuan, Yue Wu, Jianqing She","doi":"10.1002/smsc.202300337","DOIUrl":"https://doi.org/10.1002/smsc.202300337","url":null,"abstract":"Aims: Heart failure (HF) is associated with profound changes in cardiac metabolism. At present, there is still a lack of relevant research to explore the key microbiome and their metabolites affecting the progression of HF. Herein, the interaction of gut microbiota and circulating free fatty acid (FFA) in HF patients and mice is investigated. Methods and Results: In HF patients, by applying metagenomics analysis and targeted FFA metabolomics, enriched abundance of <i>Clostridium sporogenes</i> (<i>C.sp</i>) in early and late stage of HF patients, which negatively correlated to saturated free fatty acid (SFA) levels, is identified. KEGG analysis further indicates microbiota gene enrichment in FFA degradation in early HF, and decreased gene expression in FFA synthesis in late HF. In HF mice (C57BL/6J) induced by isoproterenol (ISO), impaired intestinal permeability is observed, and decreased fecal <i>C.sp</i> and increased SFA are further validated. At last, by supplementing <i>C.sp</i> to ISO-induced HF mice, the cardiac function, fibrosis, and myocardial size are partially rescued, together with decreased circulating SFA levels. Conclusions: <i>Clostridium</i> abundance is increased in HF, compensating cardiac function deterioration via downregulation of circulating SFA levels. The results demonstrate that the gut microbiota–SFA axis plays an important role in HF protection, which may provide a strategic advantage for the probiotic therapy development in HF.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"35 1","pages":""},"PeriodicalIF":12.7,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141572415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Small SciencePub Date : 2024-07-08DOI: 10.1002/smsc.202400122
Fabiana Giglio, Carmen Scieuzo, Sofia Ouazri, Valentina Pucciarelli, Dolores Ianniciello, Sophia Letcher, Rosanna Salvia, Ambrogio Laginestra, David L. Kaplan, Patrizia Falabella
{"title":"A Glance into the Near Future: Cultivated Meat from Mammalian and Insect Cells","authors":"Fabiana Giglio, Carmen Scieuzo, Sofia Ouazri, Valentina Pucciarelli, Dolores Ianniciello, Sophia Letcher, Rosanna Salvia, Ambrogio Laginestra, David L. Kaplan, Patrizia Falabella","doi":"10.1002/smsc.202400122","DOIUrl":"https://doi.org/10.1002/smsc.202400122","url":null,"abstract":"The increasing global population and demand for meat have led to the need to find sustainable and viable alternatives to traditional production methods. One potential solution is cultivated meat (CM), which involves producing meat in vitro from animal stem cells to generate products with nutritional and sensory properties similar to conventional livestock-derived meat. This article examines current approaches to CM production and investigates how using insect cells could enhance the process. Cell sources are a critical issue in CM production, alongside advances in culture media, bioreactors for scalability, and scaffold development. Insect cells, compared to commonly used mammalian cells, may offer advantages in overcoming technological challenges that hinder cell culture development and expansion. The objective of this review is to emphasize how insects, as a cell source for CM production, could offer a more sustainable option. A crucial aspect for achieving this goal is a comprehensive understanding of the physiology of muscle and fat cells. In this work, the characteristics of insect and mammalian cells are compared, focusing particularly on muscle and fat cell development, regulatory pathways, hormonal regulation, and tissue composition. Insect cells are a promising source for CM, offering a sustainable and environmentally friendly alternative.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"73 1","pages":""},"PeriodicalIF":12.7,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141577694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Zero-Dimensional Interstitial Electron-Induced Spin–Orbit Coupling Dirac States in Sandwich Electride","authors":"Weizhen Meng, Jiayu Jiang, Yalong Jiao, Fengxian Ma, Ying Yang, Zhenxiang Cheng, Xiaotian Wang","doi":"10.1002/smsc.202400131","DOIUrl":"https://doi.org/10.1002/smsc.202400131","url":null,"abstract":"The development of inorganic electrides offers new possibilities for studying topological states due to the nonnuclear-binding properties displayed by interstitial electrons. Herein, a sandwich electride 2[CaCl]<sup>+</sup>:2e<sup>−</sup> is designed, featuring a tetragonal lattice structure, including two atomic lattice layers and one interstitial electron layer. The interstitial electrons form nonsymmorphic-symmetry-protected Dirac points (DPs) at the X and M points, which are robust against the spin–orbit coupling effect. DPs exhibit an approximately elliptical shape, characterized by a relatively high anisotropy, resulting from the interplay between the electron and atomic layers. In addition, 2[CaCl]<sup>+</sup>:2e<sup>−</sup> possesses a lower work function (WF) (3.43 eV), endowing it with robust electron-supplying characteristics. Due to the low WF and interstitial electrons, 2[CaCl]<sup>+</sup>:2e<sup>−</sup> loaded Ru shows outstanding catalytic performance for N<sub>2</sub> cleavage. A potential research platform for exploring the formation of topological states and promoting nitrogen cracking in electrides is provided.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"24 1","pages":""},"PeriodicalIF":12.7,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141547914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Small SciencePub Date : 2024-07-04DOI: 10.1002/smsc.202400133
P. Monalisha, Maria Ameziane, Irena Spasojevic, Eva Pellicer, Rhodri Mansell, Enric Menéndez, Sebastiaan van Dijken, Jordi Sort
{"title":"Magnetoionics for Synaptic Devices and Neuromorphic Computing: Recent Advances, Challenges, and Future Perspectives","authors":"P. Monalisha, Maria Ameziane, Irena Spasojevic, Eva Pellicer, Rhodri Mansell, Enric Menéndez, Sebastiaan van Dijken, Jordi Sort","doi":"10.1002/smsc.202400133","DOIUrl":"https://doi.org/10.1002/smsc.202400133","url":null,"abstract":"With the advent of Big Data, traditional digital computing is struggling to cope with intricate tasks related to data classification or pattern recognition. To mitigate this limitation, software-based neural networks are implemented, but they are run in conventional computers whose operation principle (with separate memory and data-processing units) is highly inefficient compared to the human brain. Brain-inspired in-memory computing is achieved through a wide variety of methods, for example, artificial synapses, spiking neural networks, or reservoir computing. However, most of these methods use materials (e.g., memristor arrays, spintronics, phase change memories) operated with electric currents, resulting in significant Joule heating effect. Tuning magnetic properties by voltage-driven ion motion (i.e., magnetoionics) has recently emerged as an alternative energy-efficient approach to emulate functionalities of biological synapses: potentiation/depression, multilevel storage, or transitions from short-term to long-term plasticity. In this perspective, the use of magnetoionics in neuromorphic applications is critically reviewed, with emphasis on modulating synaptic weight through: 1) control of magnetization by voltage-induced ion retrieval/insertion; and 2) control of magnetic stripe domains and skyrmions in gated magnetic thin films adjacent to solid-state ionic supercapacitors. The potential prospects in this emerging research area together with a forward-looking discussion on future opportunities are provided.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"59 1","pages":""},"PeriodicalIF":12.7,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141547913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Small SciencePub Date : 2024-07-04DOI: 10.1002/smsc.202400220
Xiao-Dong Zhang, Hui-Juan Yu, Shao-Qi Guan, Yu-Lin Lu, Yu Zhang, Yin-Hui Huang, Ya-Ping Wang, Chen-Hui Liu, Zhong-Min Cao, Yu-Han Qin, Mei Pan, Jun Shen, Cheng-Yong Su
{"title":"A Highly Charged Positive Cage Causes Simultaneous Enhancement of Type-II and O2-Independent-Type-I Photodynamic Therapy via One-/Two-Photon Stimulation and Tumor Immunotherapy via PANoptosis and Ferroptosis","authors":"Xiao-Dong Zhang, Hui-Juan Yu, Shao-Qi Guan, Yu-Lin Lu, Yu Zhang, Yin-Hui Huang, Ya-Ping Wang, Chen-Hui Liu, Zhong-Min Cao, Yu-Han Qin, Mei Pan, Jun Shen, Cheng-Yong Su","doi":"10.1002/smsc.202400220","DOIUrl":"https://doi.org/10.1002/smsc.202400220","url":null,"abstract":"To solve the oxygen dependence problem of photodynamic therapy (PDT), it is critical to explore photosensitizers that do not rely on O<sub>2</sub> molecule to generate reactive oxygen species (ROS). Herein, a stable cationic metal-organic cage [Pd<sub>6</sub>(RuL<sup>oz</sup><sub>3</sub>)<sub>8</sub>](BF<sub>4</sub>)<sub>28</sub> (MOC-88) that possesses high +28 charges is designed. The cage-confined positive microenvironment enables efficient generation of hydroxyl radicals and improved yield of the singlet oxygen under one-/two-photon excitation, showing excellent performance to concurrently enhance Type-II and O<sub>2</sub>-independent-Type-I PDT. Moreover, the effective ROS production and robust lipid peroxidation trigger a series of signaling pathways (inflammasome, cyclic guanosine monophosphate–adenosine monophosphate synthase stimulator of interferon genes, and NF-κB) to evoke PANoptosis and ferroptosis in tumor cells, enabling MOC-88 to simultaneously cause the loss of cell membrane integrity, release a series of inflammatory cytokines and damage-associated molecular patterns, stimulate the maturation and antigen presentation ability of dendritic cells, and ultimately activate T-cell-dependent adaptive immunity in vivo to inhibit tumor growth.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"24 1","pages":""},"PeriodicalIF":12.7,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141547912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Small SciencePub Date : 2024-07-03DOI: 10.1002/smsc.202400189
Jordan Hobbs, Calum J. Gibb, Richard J. Mandle
{"title":"Emergent Antiferroelectric Ordering and the Coupling of Liquid Crystalline and Polar Order","authors":"Jordan Hobbs, Calum J. Gibb, Richard J. Mandle","doi":"10.1002/smsc.202400189","DOIUrl":"https://doi.org/10.1002/smsc.202400189","url":null,"abstract":"Polar liquid crystals possess 3D orientational order coupled with unidirectional electric polarity, yielding fluid ferroelectrics. Such polar phases are generated by rod-like molecules with large electric dipole moments. 2,5-Disubstituted 1,3-dioxane is commonly employed as a polar motif in said systems, and herein it is shown to suffer from thermal instability as a consequence of equatorial-trans to axial-trans isomerism at elevated temperatures. Isosteric building blocks are utilized as potential replacements for the 1,3-dioxane unit, and in doing so new examples of fluid ferroelectric systems are obtained. For binary mixtures of certain composition, the emergence of a new fluid antiferroelectric phase, a finding not observed for either of the parent molecules, is observed. This study also reveals a critical tipping point for the emergence of polar order in otherwise apolar systems. These results hint at the possibility for uncovering new highly ordered polar liquid-crystalline phases and delineate distinct transition mechanisms in orientational and polar ordering.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"40 1","pages":""},"PeriodicalIF":12.7,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141547988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Novel Piezo1 Agonist Promoting Mesenchymal Stem Cell Proliferation and Osteogenesis to Attenuate Disuse Osteoporosis","authors":"Ruihan Hao, Hairong Tang, Chunyong Ding, Bhavana Rajbanshi, Yuhang Liu, Ding Ma, Zhouyi Duan, Yuxin Qi, Liming Dai, Bingjun Zhang, Ao Zhang, Xiaoling Zhang","doi":"10.1002/smsc.202400061","DOIUrl":"https://doi.org/10.1002/smsc.202400061","url":null,"abstract":"Disuse osteoporosis (OP) is a state of bone loss due to lack of mechanical stimuli, probably induced by prolonged bed rest, neurological diseases, as well as microgravity. Currently the precise treatment strategies of disuse OP remain largely unexplored. Piezo1, a mechanosensitive calcium (Ca<sup>2+</sup>) ion channel, is a key force sensor mediating mechanotransduction and it is demonstrated to regulate bone homeostasis and osteogenesis in response to mechanical forces. Using structure-based drug design, a novel small-molecule Piezo1 agonist, MCB-22-174, which can effectively activate Piezo1 and initiate Ca<sup>2+</sup> influx, is developed and is more potent than the canonical Piezo1 agonist, Yoda1. Moreover, MCB-22-174 is found as a safe Piezo1 agonist without any signs of serious toxicity. Mechanistically, Piezo1 activation promotes the proliferation of bone marrow mesenchymal stem cells by activating the Ca<sup>2+</sup>-related extracellular signal-related kinases and calcium–calmodulin (CaM)-dependent protein kinase II (CaMKII) pathway. Importantly, MCB-22-174 could effectively promote osteogenesis and attenuate disuse OP in vivo. Overall, the findings provide a promising therapeutic strategy for disuse OP by chemical activation of Piezo1.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"35 1","pages":""},"PeriodicalIF":12.7,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141527483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Body-Integrated Ultrasensitive All-Textile Pressure Sensors for Skin-Inspired Artificial Sensory Systems","authors":"Bingjun Wang, Yuanhong Shi, Haotian Li, Qilin Hua, Keyu Ji, Zilong Dong, Zhaowei Cui, Tianci Huang, Zhongming Chen, Ruilai Wei, Weiguo Hu, Guozhen Shen","doi":"10.1002/smsc.202400026","DOIUrl":"https://doi.org/10.1002/smsc.202400026","url":null,"abstract":"Tactile sensing plays a vital role in human somatosensory perception as it provides essential touch information necessary for interacting with the environment and accomplishing daily tasks. The progress in textile electronics has opened up opportunities for developing intelligent wearable devices that enable somatosensory perception and interaction. Herein, a skin-inspired all-textile pressure sensor (ATP) is presented that emulates the sensing and interaction functions of human skin, offering wearability, comfort, and breathability. The ATP demonstrates impressive features, including ultrahigh sensitivity (1.46 × 10<sup>6</sup> kPa<sup>−1</sup>), fast response time (1 ms), excellent stability and durability (over 2000 compression-release cycles), a low detection limit of 10 Pa, and remarkable breathability (93.2%). The multipixel array of ATPs has been proven to facilitate static and dynamic mapping of spatial pressure, as well as pressure trajectory monitoring functions. Moreover, by integrating ATP with oscillation circuits, external force stimuli can be directly encoded into digital frequency pulses that resemble human physiological signals. The frequency of output pulses increases with the applied pressure. Consequently, an ATP-based artificial sensory system is constructed for intelligent tactile perception. This work provides a simple and versatile strategy for practical applications of wearable electronics in the fields of robotics, sports science, and human–machine interfaces technologies.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"143 1","pages":""},"PeriodicalIF":12.7,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141527482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Small SciencePub Date : 2024-06-30DOI: 10.1002/smsc.202400114
James P. Barnard, Jianan Shen, Benson Kunhung Tsai, Yizhi Zhang, Max R. Chhabra, Ke Xu, Xinghang Zhang, Raktim Sarma, Aleem Siddiqui, Haiyan Wang
{"title":"Large Area Transfer of Bismuth-Based Layered Oxide Thin Films Using a Flexible Polymer Transfer Method","authors":"James P. Barnard, Jianan Shen, Benson Kunhung Tsai, Yizhi Zhang, Max R. Chhabra, Ke Xu, Xinghang Zhang, Raktim Sarma, Aleem Siddiqui, Haiyan Wang","doi":"10.1002/smsc.202400114","DOIUrl":"https://doi.org/10.1002/smsc.202400114","url":null,"abstract":"Magnetic and ferroelectric oxide thin films have long been studied for their applications in electronics, optics, and sensors. The properties of these oxide thin films are highly dependent on the film growth quality and conditions. To maximize the film quality, epitaxial oxide thin films are frequently grown on single-crystal oxide substrates such as strontium titanate (SrTiO<sub>3</sub>) and lanthanum aluminate (LaAlO<sub>3</sub>) to satisfy lattice matching and minimize defect formation. However, these single-crystal oxide substrates cannot readily be used in practical applications due to their high cost, limited availability, and small wafer sizes. One leading solution to this challenge is film transfer. In this demonstration, a material from a new class of multiferroic oxides is selected, namely bismuth-based layered oxides, for the transfer. A water-soluble sacrificial layer of Sr<sub>3</sub>Al<sub>2</sub>O<sub>6</sub> is inserted between the oxide substrate and the film, enabling the release of the film from the original substrate onto a polymer support layer. The films are transferred onto new substrates of silicon and lithium niobate (LiNbO<sub>3</sub>) and the polymer layer is removed. These substrates allow for the future design of electronic and optical devices as well as sensors using this new group of multiferroic layered oxide films.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"72 1","pages":""},"PeriodicalIF":12.7,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141505737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}