Small Science最新文献

Fluorescent Self-Healing Elastomers with Triple Dynamic Bonds for 2D/3D Printed Information Encryption. 具有三动态键的荧光自修复弹性体用于2D/3D打印信息加密。

IF 8.3

Small Science Pub Date : 2025-07-30 eCollection Date: 2025-09-01 DOI: 10.1002/smsc.202500091

Dai Yang, Qingyong Tian, Jingyang Li, Xiaoqing Sui, Shuiren Liu, Xiaoguang Hu, Qingqing Sun, Linlin Zhang, Mingjun Niu, Xuying Liu, Weijing Yao

{"title":"Fluorescent Self-Healing Elastomers with Triple Dynamic Bonds for 2D/3D Printed Information Encryption.","authors":"Dai Yang, Qingyong Tian, Jingyang Li, Xiaoqing Sui, Shuiren Liu, Xiaoguang Hu, Qingqing Sun, Linlin Zhang, Mingjun Niu, Xuying Liu, Weijing Yao","doi":"10.1002/smsc.202500091","DOIUrl":"10.1002/smsc.202500091","url":null,"abstract":"The development of novel optical self-healing materials holds significant importance for applications in anticounterfeiting and information encryption, but remains a formidable challenge. This study presents a fluorescent self-healing material designed for 2D/3D printing anticounterfeiting applications, exhibiting outstanding properties such as high transmittance, excellent mechanical strength, and remarkable self-healing efficiency. The triple dynamic bond networks provide robust mechanical and self-healing capabilities, with the polymer demonstrating a tensile strength of 26.9 MPa, an elongation at break of 1400%, toughness of 149.4 MJ m-3, and a self-healing efficiency of 97%. When incorporated with core-shell nanoparticles, the polymer forms a fluorescent elastomer capable of triple-mode up/down conversion fluorescence emission. This material can be easily customized via 2D/3D printing to create the desired shapes, and its self-healing property allows for the combination of various configurations, thereby facilitating the encryption of multiple information applications. This study presents an effective protocol for synthesizing fluorescent self-healing materials, further advancing their potentials for use in information encryption and fluorescence-based anti-counterfeiting.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 9","pages":"2500091"},"PeriodicalIF":8.3,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412527/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Toward Standardized Microscale Tensile Testing for Two-Photon Polymerization-Fabricated Materials in Liquid. 液体中双光子聚合制备材料的标准化微尺度拉伸试验研究。

IF 8.3

Small Science Pub Date : 2025-07-22 eCollection Date: 2025-09-01 DOI: 10.1002/smsc.202500228

Grayson Minnick, Timothy Goldsmith, Bahareh Tajvidi Safa, Amir Ostadi Moghaddam, Jordan Rosenbohm, Nickolay V Lavrik, Wei Gao, Ruiguo Yang

{"title":"Toward Standardized Microscale Tensile Testing for Two-Photon Polymerization-Fabricated Materials in Liquid.","authors":"Grayson Minnick, Timothy Goldsmith, Bahareh Tajvidi Safa, Amir Ostadi Moghaddam, Jordan Rosenbohm, Nickolay V Lavrik, Wei Gao, Ruiguo Yang","doi":"10.1002/smsc.202500228","DOIUrl":"10.1002/smsc.202500228","url":null,"abstract":"Two-photon polymerization (TPP) enables the fabrication of intricate 3D microstructures with submicron precision, offering significant potential in biomedical applications like tissue engineering. In such applications, to print materials and structures with defined mechanics, it is crucial to understand how TPP printing parameters impact the material properties in a physiologically relevant liquid environment. Herein, an experimental approach utilizing microscale tensile testing (μTT) for the systematic measurement of TPP-fabricated microfibers submerged in liquid as a function of printing parameters is introduced. Using a diurethane dimethacrylate-based resin, the influence of printing parameters on microfiber geometry is first explored, demonstrating cross-sectional areas ranging from 1 to 36 μm2. Tensile testing reveals Young's moduli between 0.5 and 1.5 GPa and yield strengths from 10 to 60 MPa. The experimental data show an excellent fit with the Ogden hyperelastic polymer model, which enables a detailed analysis of how variations in writing speed, laser power, and printing path influence the mechanical properties of TPP microfibers. The μTT method is also showcased for evaluating multiple commercial resins and for performing cyclic loading experiments. Collectively, this study builds a foundation toward a standardized microscale tensile testing framework to characterize the mechanical properties of TPP printed structures.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 9","pages":"2500228"},"PeriodicalIF":8.3,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Label-Free Machine Learning Prediction of Chemotherapy on Tumor Spheroids Using a Microfluidics Droplet Platform. 使用微流体液滴平台的无标记机器学习预测肿瘤球体化疗。

IF 8.3

Small Science Pub Date : 2025-07-16 eCollection Date: 2025-09-01 DOI: 10.1002/smsc.202500173

Caroline Parent, Hasti Honari, Tiziana Tocci, Franck Simon, Sakina Zaidi, Audric Jan, Vivian Aubert, Olivier Delattre, Hervé Isambert, Claire Wilhelm, Jean-Louis Viovy

{"title":"Label-Free Machine Learning Prediction of Chemotherapy on Tumor Spheroids Using a Microfluidics Droplet Platform.","authors":"Caroline Parent, Hasti Honari, Tiziana Tocci, Franck Simon, Sakina Zaidi, Audric Jan, Vivian Aubert, Olivier Delattre, Hervé Isambert, Claire Wilhelm, Jean-Louis Viovy","doi":"10.1002/smsc.202500173","DOIUrl":"10.1002/smsc.202500173","url":null,"abstract":"An integrated approach is proposed to rapidly evaluate the effects of anticancer treatments in 3D models, combining a droplet-based microfluidic platform for spheroid formation and single-spheroid chemotherapy application, label-free morphological analysis, and machine learning to assess treatment response. Morphological features of spheroids, such as size and color intensity, are extracted and selected using the multivariate information-based inductive causation algorithm, and used to train a neural network for spheroid classification into viability classes, derived from metabolic assays performed within the same platform as a benchmark. The model is tested on Ewing sarcoma cell lines and patient-derived xenograft (PDX) cells, demonstrating robust performance across datasets. It accurately predicts spheroid viability, used to generate dose-response curves and to determine half maximal inhibitory concentration (IC50) values comparable to traditional biochemical assays. Notably, a model trained on cell line spheroids successfully classifies PDX spheroids, highlighting its adaptability. Compared to convolutional neural network-based approaches, this method works with smaller training datasets and provides greater interpretability by identifying key morphological features. The droplet platform further reduces cell requirements, while single-spheroid confinement enhances classification quality. Overall, this label-free experimental and analytical platform is confirmed as a scalable, efficient, and dynamic tool for drug screening.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 9","pages":"2500173"},"PeriodicalIF":8.3,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-Yield Convenient Mass Production of High-Quality Homogenous Human Induced Pluripotent Stem Cell Spheroids under Rho-Associated Kinase Inhibitor-Free 3D Culture Enabled by Micropatterning and Cold-Triggered Chemical-Free Cell Detachment. 在无rho相关激酶抑制剂的3D培养下，通过微图案和冷触发的无化学物质细胞分离实现高产量，方便批量生产高质量的同质人诱导多能干细胞球体。

IF 8.3

Small Science Pub Date : 2025-07-11 eCollection Date: 2025-09-01 DOI: 10.1002/smsc.202500201

Zhiyuan Wang, Samantha Stewart, Mitsuo Kumagai, Ethan Wang, Wenquan Ou, Yongyu Lu, Taotao Meng, Cancan Xu, Yi Hong, Shenqiang Ren, Xiaoming He

{"title":"High-Yield Convenient Mass Production of High-Quality Homogenous Human Induced Pluripotent Stem Cell Spheroids under Rho-Associated Kinase Inhibitor-Free 3D Culture Enabled by Micropatterning and Cold-Triggered Chemical-Free Cell Detachment.","authors":"Zhiyuan Wang, Samantha Stewart, Mitsuo Kumagai, Ethan Wang, Wenquan Ou, Yongyu Lu, Taotao Meng, Cancan Xu, Yi Hong, Shenqiang Ren, Xiaoming He","doi":"10.1002/smsc.202500201","DOIUrl":"10.1002/smsc.202500201","url":null,"abstract":"Human induced pluripotent stem cells (hiPSCs) show great promise for personalized cell-based medicine, as they can be derived from easily accessible somatic cells and differentiated into all three germ layers without ethical concerns. This requires mass production of hiPSCs in 3D. However, contemporary methods for 3D culture result in hiPSC spheroids with significant size heterogeneity that is undesired for controlled differentiation and require the use of a high concentration of Rho-associated kinase inhibitor (RI) to improve the cell viability. Unfortunately, a high concentration of RI causes uncontrolled spontaneous differentiation. To address these challenges, a cold-responsive micropatterned dish (crMPD) is developed by spin-coating a thin layer of cold-responsive polymer on a cell culture dish and further microcontact printing cell attachment micropatterns on top of the coating layer. The hiPSCs attach and proliferate exclusively within the micropatterned areas to form a large number of uniform hiPSC colonies that can be detached as a whole by putting the crMPD on ice for ≈5-15 min. Under 3D culture without RI, the colonies can quickly self-assemble into homogeneous hiPSC spheroids with high viability, yield, and pluripotency. This ingeniouscrMPD technology may be invaluable to facilitate widespread application of hiPSCs in research and personalized medicine.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 9","pages":"2500201"},"PeriodicalIF":8.3,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic Implications of Biomolecular Corona on Lipid Nanoparticle-Based Gene Delivery Systems. 生物分子电晕对基于脂质纳米颗粒的基因传递系统的治疗意义。

IF 8.3

Small Science Pub Date : 2025-07-09 eCollection Date: 2025-09-01 DOI: 10.1002/smsc.202500206

Antonietta Greco, Claudia Corbo

引用次数: 0

High-Speed Atomic Force Microscopy Reveals the Dynamic Interplay of Membrane Proteins is Lipid-Modulated. 高速原子力显微镜揭示膜蛋白的动态相互作用是脂质调节的。

IF 8.3

Small Science Pub Date : 2025-07-08 eCollection Date: 2025-09-01 DOI: 10.1002/smsc.202500258

Eunji Shin, Yining Jiang, Batiste Thienpont, James N Sturgis, Simon Scheuring

{"title":"High-Speed Atomic Force Microscopy Reveals the Dynamic Interplay of Membrane Proteins is Lipid-Modulated.","authors":"Eunji Shin, Yining Jiang, Batiste Thienpont, James N Sturgis, Simon Scheuring","doi":"10.1002/smsc.202500258","DOIUrl":"10.1002/smsc.202500258","url":null,"abstract":"The solvent of membrane proteins is the membrane lipids in which they are embedded. Therefore, the nature of the lipids that surround membrane proteins impacts their dynamics and interactions. Unfortunately, how membrane proteins dynamically interact is difficult to study, and little is experimentally known how membrane proteins interplay in a membrane at the molecular scale. Herein, high-speed atomic force microscopy (HS-AFM) is used to dynamically image a well-controlled bottom-up system consisting of two aquaporin-fold membrane proteins, pentameric FocA and tetrameric GlpF, that interact in membranes composed of varying amounts of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and E. coli lipids. It is found that the lipid environment significantly influences membrane protein mobility and interaction, where increased E. coli lipid content reduces protein movement, while DOPC-rich environments promote mobility. Furthermore, the supramolecular structures of the membrane proteins and protomer interactions in clusters are also lipid modulated, where E. coli lipids favor specific protein-protein interactions, whereas greater interaction variability is found in DOPC. These findings highlight the role of lipids in regulating protein diffusion and interactions and suggest that lipid-protein interaction energetics play a significant role in controlling membrane protein interactions and supramolecular assembly.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 9","pages":"2500258"},"PeriodicalIF":8.3,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surface Reconstruction in Quasi-2D Perovskite Films Treated with Cesium Halide Nanocrystals: Halide Exchange or Phase Transformation. 卤化铯纳米晶处理准二维钙钛矿薄膜的表面重建：卤化物交换或相变。

IF 8.3

Small Science Pub Date : 2025-07-08 eCollection Date: 2025-09-01 DOI: 10.1002/smsc.202500163

Dong Il Son, Seonhong Min, Sohyeon An, Dongryeol Lee, Se Hyun Lee, Donghan Kim, Myoung Hoon Song, Jin Young Kim, Sungwook Park, Junsang Cho, Jongnam Park

{"title":"Surface Reconstruction in Quasi-2D Perovskite Films Treated with Cesium Halide Nanocrystals: Halide Exchange or Phase Transformation.","authors":"Dong Il Son, Seonhong Min, Sohyeon An, Dongryeol Lee, Se Hyun Lee, Donghan Kim, Myoung Hoon Song, Jin Young Kim, Sungwook Park, Junsang Cho, Jongnam Park","doi":"10.1002/smsc.202500163","DOIUrl":"10.1002/smsc.202500163","url":null,"abstract":"The formation of heterostructure interfaces from quantum dots (or nanocrystals) and lower-dimensional (2D or quasi-2D) materials enables interfacial and optoelectronic property tuning. However, this strategy has not been sufficiently characterized, for example, the application of cesium halide nanocrystals to quasi-2D perovskite structures is underexplored, and the mechanisms of the resulting structural modifications and specific nanocrystal roles are not fully understood. Herein, the effects of postsynthetically surface-modifying quasi-2D perovskite films with CsX (X = Cl, Br, I) nanocrystals are examined to bridge this gap. The purposeful choice of X enables the selective induction of halide exchange or a structural phase transformation at the nanocrystal-perovskite interface, which leads to optical bandgap and luminescence property modulation over a wide range of the visible spectrum (450-620 nm). Results of in situ spectroscopic analyses and temperature-dependent kinetic studies reveal that the activation energy for the halide exchange (24-29 kJ mol-1) is lower than that for the structural phase transformation to 0D Cs4PbX6 nanocrystals (39 kJ mol-1), indicating the kinetic favorability of the former process. The potential of the developed strategy is showcased through the fabrication of efficient color-tunable light-emitting diodes with quasi-2D perovskite films surface modified with CsX as active emission layers.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 9","pages":"2500163"},"PeriodicalIF":8.3,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

One-Step Solid-State Synthesis of Sandwich-like, Porous C-SnS₂ Matrix Composites as Anode Materials for Rechargeable Lithium Ion Batteries. 一步固态合成三明治状多孔C-SnS2基复合材料作为可充电锂离子电池负极材料。

IF 8.3

Small Science Pub Date : 2025-07-07 eCollection Date: 2025-09-01 DOI: 10.1002/smsc.202500192

Akzhan Bekzhanov, Irshad Mohammad, Lukas Sallfeldner, Freddy Kleitz, Damian Cupid

{"title":"One-Step Solid-State Synthesis of Sandwich-like, Porous C-SnS2 Matrix Composites as Anode Materials for Rechargeable Lithium Ion Batteries.","authors":"Akzhan Bekzhanov, Irshad Mohammad, Lukas Sallfeldner, Freddy Kleitz, Damian Cupid","doi":"10.1002/smsc.202500192","DOIUrl":"10.1002/smsc.202500192","url":null,"abstract":"SnS2 (tin disulfide) is a promising anode active material for lithium-ion batteries (LIBs) due to its high theoretical capacity and low material cost. Conventional synthesis methods, such as solvothermal, hydrothermal, and solid-state, require long synthesis times, the use of solvents and surfactants, and several separation steps. However, the preparation of coated SnS2 composites using liquid media is even more complex, requiring suitable precursors, compatible solvents, and potentially several steps. In the present work, a one-step solid-state method is developed to synthesize SnS2 particles sandwiched in a porous polyacrylonitrile (PAN)-based matrix phase (C-SnS2) for use as anode active materials for LIBs. The as-synthesized materials exhibit a reversible capacity of 720 mAh g-1 after 100 cycles when tested versus Li/Li+. The performance of this SnS2-based anode active material is compared to that prepared by the solid-state heat treatment of SnS2, both with and without PAN. The structure, morphology, chemistry, and electrochemical properties of these compounds are established and comprehensively compared to each other. The observed superior cycling stability and rate capability of the sandwich-like C-SnS2 are attributed to its phase purity and its incorporation in a porous, conductive, carbonized PAN matrix.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 9","pages":"2500192"},"PeriodicalIF":8.3,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low-Temperature Photocrystallization of Atomic Layer Deposition-Processed Tin Oxide for Highly Efficient and Flexible Perovskite Solar Cells. 用于高效柔性钙钛矿太阳能电池的原子层沉积处理氧化锡低温光结晶。

IF 8.3

Small Science Pub Date : 2025-07-07 eCollection Date: 2025-09-01 DOI: 10.1002/smsc.202500196

Dayeon Ko, Se Hun Joo, Sol Kim, In Soo Kim, Minwoo Park

{"title":"Low-Temperature Photocrystallization of Atomic Layer Deposition-Processed Tin Oxide for Highly Efficient and Flexible Perovskite Solar Cells.","authors":"Dayeon Ko, Se Hun Joo, Sol Kim, In Soo Kim, Minwoo Park","doi":"10.1002/smsc.202500196","DOIUrl":"10.1002/smsc.202500196","url":null,"abstract":"Atomic layer deposition (ALD) enables an excellent surface coverage and uniformity in the preparation of large-area metal-oxide thin films. In particular, ALD-processed SnO2 has demonstrated great potential as an electron transport layer in flexible perovskite solar cells (PSCs) and tandem modules. However, the poor electrical conductivities and surface wettabilities of amorphous SnO2 remain critical challenges for commercialization. In this study, a low-temperature and rapid crystallization process for amorphous SnO2 is introduced, based on the use of high-power ultraviolet (UV) exposure (UV-SnO2) to achieve high-performance flexible PSCs. The generation of highly dense O3/OH radicals under UV exposure effectively ruptures the imperfect and weak bonds in the SnO2 matrix, thereby facilitating the formation of nanocrystalline SnO2. This transformation enhances the conductivity and shifts the energy levels upward, promoting electron injection and transfer from the perovskite. Rigid and flexible devices exhibit remarkable power conversion efficiencies (PCEs) of 22.86 and 21.49%, respectively. Furthermore, the flexible device demonstrates an excellent mechanical durability and environmental stability, retaining 93.3% of its initial PCE after 1500 bending cycles (r = 12 mm) and 87.4% after 1000 h under 1 sun illumination. These results highlight the potential of photocrystallization for advancing flexible PSC technologies.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 9","pages":"2500196"},"PeriodicalIF":8.3,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficient Electrochemical CO₂ Reduction Using AgN₃ Single-Atom Sites Embedded in Free-Standing Electrodes for Flow Cell Applications. 利用AgN3单原子位嵌入流动电池的独立电极中，实现高效的电化学CO2还原。

IF 8.3

Small Science Pub Date : 2025-07-06 eCollection Date: 2025-08-01 DOI: 10.1002/smsc.202400643

M Nur Hossain, Ali Malek, Zhangsen Chen, Lei Zhang, Shuhui Sun, Hanshuo Liu, Roberto Neagu, Jigang Zhou, Hui Yuan, Christopher S Allen, Gianluigi Botton

{"title":"Efficient Electrochemical CO2 Reduction Using AgN3 Single-Atom Sites Embedded in Free-Standing Electrodes for Flow Cell Applications.","authors":"M Nur Hossain, Ali Malek, Zhangsen Chen, Lei Zhang, Shuhui Sun, Hanshuo Liu, Roberto Neagu, Jigang Zhou, Hui Yuan, Christopher S Allen, Gianluigi Botton","doi":"10.1002/smsc.202400643","DOIUrl":"10.1002/smsc.202400643","url":null,"abstract":"The electrochemical reduction of CO2 into valuable chemicals presents a promising strategy for carbon utilization; however, it remains challenging due to low activity, poor selectivity and stability of existing catalysts. In this study, we report the fabrication of free-standing silver single-atom catalysts (Ag SACs) designed for the efficient conversion of CO2 to carbon monoxide (CO) at high current densities in a bicarbonate electrolyzer. The Ag single atoms dispersed within a carbon matrix, forming Ag-N3 active sites for the electrocatalytic CO2 reduction reaction (CO2 RR). The catalytic activity and stability of the free-standing Ag SACs are evaluated at a current density of 100 mA cm-2, demonstrating prolonged electrolysis with consistent Faradaic efficiency for CO production. Density functional theory calculations revealed that the Ag-N3 active site significantly lowers the energy barriers for the CO2 absorption step compared to Ag-Ag and Ag-Ni sites, facilitating CO2 activation and contributing to enhanced catalytic activity and stability during CO2 reduction. Detailed analysis of the electronic structure and coordination environment further validates the superior performance of the Ag-N3 site in the free-standing Ag SACs, underscoring their effectiveness in CO2 electroreduction. These findings highlight the potential of the free-standing Ag SACs to advance CO2 reduction technologies, offering enhanced efficiency and selectivity for CO2 conversion.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 8","pages":"2400643"},"PeriodicalIF":8.3,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0