Small Science最新文献_第7页

Nanoengineered Shape-Memory Hemostat. 纳米工程形状记忆止血器。

IF 11.1

Small Science Pub Date : 2024-12-11 eCollection Date: 2025-02-01 DOI: 10.1002/smsc.202400321

Sarah E Hargett, Giriraj K Lokhande, Joseph Duran, Zanir Hirani, Lindy K Jang, Samantha Foster, Kaivalya A Deo, Sasha George, Mahjabeen Javed, Taylor H Ware, Duncan J Maitland, Akhilesh K Gaharwar

{"title":"Nanoengineered Shape-Memory Hemostat.","authors":"Sarah E Hargett, Giriraj K Lokhande, Joseph Duran, Zanir Hirani, Lindy K Jang, Samantha Foster, Kaivalya A Deo, Sasha George, Mahjabeen Javed, Taylor H Ware, Duncan J Maitland, Akhilesh K Gaharwar","doi":"10.1002/smsc.202400321","DOIUrl":"https://doi.org/10.1002/smsc.202400321","url":null,"abstract":"Uncontrolled hemorrhage is the predominant cause of preventable combat deaths. Various biomaterials serve as hemostatic agents due to their procoagulant or absorptive activity. However, these biomaterials often lack expansion capabilities, which severely limits use in noncompressible wounds. This study combines a hemostatic nanocomposite with a shape-memory polymer foam to design a composite material with both hemostatic and physical expansion properties. This composite is fabricated in two formulations: a foam externally coated in a highly concentrated nanocomposite (\"coated composite\") and a foam containing a diluted nanocomposite infused throughout its pores (\"infused composite\"). Both formulations retain the shape-memory foam's expansion property. Further, the coated composite shows improved fluid uptake (>2-fold) versus infused composites or foam. The nanocomposite component dissociates from the foam under degradative conditions, with the foam remaining stable for 30 days. Hemostatic studies illustrate that the coated composite reduces the clotting time by ≈20%. Alternatively, the infused composite improves clotting over a larger distance (up to ≈2× distance from the composite). These results signify a modular hemostatic ability: the coated composite reduces clotting and improves fluid uptake, while the infused composite achieves diffuse clotting and maintains mechanical properties. Thus, these materials pose a strong potential for use in noncompressible wounds.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 2","pages":"2400321"},"PeriodicalIF":11.1,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11934902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Decellularized Cell-Secreted Extracellular Matrices as Biomaterials for Tissue Engineering. 脱细胞细胞分泌细胞外基质作为组织工程生物材料。

IF 11.1

Small Science Pub Date : 2024-12-06 eCollection Date: 2025-02-01 DOI: 10.1002/smsc.202400335

David H Ramos-Rodriguez, J Kent Leach

{"title":"Decellularized Cell-Secreted Extracellular Matrices as Biomaterials for Tissue Engineering.","authors":"David H Ramos-Rodriguez, J Kent Leach","doi":"10.1002/smsc.202400335","DOIUrl":"https://doi.org/10.1002/smsc.202400335","url":null,"abstract":"The extracellular matrix (ECM) is the naturally secreted biomaterial scaffold that provides support and regulates key aspects of cell behavior. This dynamic and complex network of structural proteins, proteoglycans, and soluble cues defines the cell microenvironment and is essential for tissue homeostasis. Because tissue engineering approaches aim to recapitulate aspects of the microenvironment to instruct tissue regeneration, ECM-inspired or -derived scaffolds are some of the earliest tissue-engineered constructs reported. However, conventional single-protein constructs fail to provide the biochemical and structural complexity of the native ECM. Decellularized ECM is under investigation to improve cell adhesion, cell remodeling, migration, proliferation, and differentiation within tissue-engineered constructs. However, challenges associated with poor mechanical properties and inherent chemical instability compared to synthetic or other natural polymers require additional considerations. This review describes the bioactive properties of ECM, current strategies to efficiently decellularize cell-secreted and tissue-derived ECM, standard fabrication techniques for ECM constructs, and current developments in the field of ECM-based musculoskeletal platforms.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 2","pages":"2400335"},"PeriodicalIF":11.1,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11934908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to "An X-Ray Absorption Spectroscopy Investigation into the Fundamental Structure of Liquid Metal Alloys". 对“液态金属合金基本结构的x射线吸收光谱研究”的修正。

IF 11.1

Small Science Pub Date : 2024-12-06 eCollection Date: 2025-01-01 DOI: 10.1002/smsc.202400581

Jaydon A Meilak, Karma Zuraiqi, Valerie Mitchell, Bernt Johannessen, Brittany V Kerr, Pierre H A Vaillant, Krystina Lamb, Patjaree Aukarasereenont, Caiden Parker, Taren Cataldo, Francois Malherbe, Andrew J Christofferson, Torben Daeneke, Rosalie K Hocking

引用次数: 0

A Corn-Based Electrically Conductive Glue for Integration of Edible Electronics. 一种用于食用电子产品集成的玉米基导电胶。

IF 11.1

Small Science Pub Date : 2024-12-05 eCollection Date: 2025-01-01 DOI: 10.1002/smsc.202400373

Noemí Contreras-Pereda, Valerio Galli, Pietro Cataldi, Valerio Francesco Annese, Giulia Coco, Athanassia Athanassiou, Alessandro Luzio, Mario Caironi

{"title":"A Corn-Based Electrically Conductive Glue for Integration of Edible Electronics.","authors":"Noemí Contreras-Pereda, Valerio Galli, Pietro Cataldi, Valerio Francesco Annese, Giulia Coco, Athanassia Athanassiou, Alessandro Luzio, Mario Caironi","doi":"10.1002/smsc.202400373","DOIUrl":"https://doi.org/10.1002/smsc.202400373","url":null,"abstract":"Edible electronics leverages the electronic properties of food-grade materials to create non-toxic technologies that can be either environmentally degraded or digested by the body after the completion of their function. Various edible electronic components have been recently proposed, and their integration into more complex circuits and systems is urgently needed for point-of-care devices. In this context, developing a safe technology for interconnecting edible components is crucial. To this aim, here an edible electrically conductive adhesive made from zein, an edible protein derived from corn, and activated carbon, a food additive, are reported. Different formulations are proposed depending on the ratio between adhesive binder (zein) and electrically conductive filler (activated carbon), evidencing a trade-off between resistivity and adhesion, passing from a 3 × 103 Ω cm resistivity and 2 MPa lap shear adhesion strength to 5 × 102 Ω cm and 0.5 MPa values upon increasing the filler content. As a proof-of-concept, the conductive adhesive is validated in different applications relevant to edible electronics, such as mounting devices on top of innovative edible substrates, interconnecting state-of-the-art edible batteries, and conforming highly adhesive electrodes for fruit monitoring.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 1","pages":"2400373"},"PeriodicalIF":11.1,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11935078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An In vitro Caco2-Based Model for Measuring Intestinal Bioadhesion Comparable to Ex vivo Models. 与离体模型相比，基于caco2的体外肠道生物黏附测量模型

IF 11.1

Small Science Pub Date : 2024-12-03 eCollection Date: 2025-02-01 DOI: 10.1002/smsc.202400461

Eliyahu Drori, Valeria Rahamim, Dhaval Patel, Yamm Anker, Sivan Meir, Gal Uzan, Shira Somech, Chen Drori, Tal Tzadok, Aharon Azagury

{"title":"An In vitro Caco2-Based Model for Measuring Intestinal Bioadhesion Comparable to Ex vivo Models.","authors":"Eliyahu Drori, Valeria Rahamim, Dhaval Patel, Yamm Anker, Sivan Meir, Gal Uzan, Shira Somech, Chen Drori, Tal Tzadok, Aharon Azagury","doi":"10.1002/smsc.202400461","DOIUrl":"https://doi.org/10.1002/smsc.202400461","url":null,"abstract":"This study presents an in vitro model using Caco-2 cells that can mimic the bioadhesion properties of the human intestinal epithelium, aiming to reduce the use of animal tissues, in line with the 3Rs principle-replacement, reduction, and refinement. Specifically, a texture analyzer was used to assess the bioadhesive strength of hydrogels (i.e., alginate (Alg), chitosan (Chit), and gelatin (Gel)) under various applied forces (20-200 mN) and contact times (120-420 s). The results demonstrate that the in vitro model effectively predicts the bioadhesive strength of the tested hydrogels to ex vivo tissues (i.e., from mice, sheep, and pigs), including the effects of applied force and contact time. Also provided is an analysis of the effect of microvilli morphology on bioadhesion where an inverse relationship was observed between microvilli linear density and bioadhesion strength, explaining the variability in results across animal models. This Caco-2-based model offers a practical, accessible, and cost-effective alternative to current ex vivo methods used for measuring bioadhesion fracture strength. It can be integrated into standardized testing protocols, providing a more ethical and scientifically robust approach to advancing bioadhesive drug delivery system research.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 2","pages":"2400461"},"PeriodicalIF":11.1,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11934890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Highly Selective Methanol Synthesis Using Electrochemical CO₂ Reduction with Defect-Engineered Cu₅₈ Nanoclusters. 缺陷工程Cu58纳米团簇电化学CO2还原制备高选择性甲醇。

IF 11.1

Small Science Pub Date : 2024-11-28 eCollection Date: 2025-02-01 DOI: 10.1002/smsc.202400465

Sourav Biswas, Tomoya Tanaka, Haohong Song, Masaki Ogami, Yamato Shingyouchi, Sakiat Hossian, Maho Kamiyama, Taiga Kosaka, Riki Nakatani, Yoshiki Niihori, Saikat Das, Tokuhisa Kawawaki, De-En Jiang, Yuichi Negishi

{"title":"Highly Selective Methanol Synthesis Using Electrochemical CO2 Reduction with Defect-Engineered Cu58 Nanoclusters.","authors":"Sourav Biswas, Tomoya Tanaka, Haohong Song, Masaki Ogami, Yamato Shingyouchi, Sakiat Hossian, Maho Kamiyama, Taiga Kosaka, Riki Nakatani, Yoshiki Niihori, Saikat Das, Tokuhisa Kawawaki, De-En Jiang, Yuichi Negishi","doi":"10.1002/smsc.202400465","DOIUrl":"https://doi.org/10.1002/smsc.202400465","url":null,"abstract":"Atomically precise copper nanoclusters (Cu NCs) exhibit significant potential as catalysts for the electrocatalytic reduction of CO2. However, the range of products achievable with these NCs has been somewhat constrained. This study presents an innovative design strategy to enhance the catalytic activity of Cu NCs by engineering their active sites. These active sites are formed here by introducing defects on cubic Cu NCs through the partial dislocation of Cu atoms at their vertices, which creates surface ligand vacancies. This dislocation further refines the internal cationic geometry by altering cuprophilic interactions, leading to distinct modifications in the edges and vertices of the cubic geometry. These unique Cu(I) atom arrangements within the cluster effectively influence product specificity during electrochemical CO2 reduction. Density functional theory calculations correlate the enhanced selectivity for CH3OH in [Cu58H20(SPr)36(PPh3)7]2+ (Pr = CH2CH2CH3) NC to the increased reactivity of edge Cu atoms in binding CO and CHO intermediates, compared to [Cu58H20(SPr)36(PPh3)8]2+ and [Cu58H20(SEt)36(PPh3)6]2+ (Et = CH2CH3) NCs. Thus, this work underscores the potential of tailored structural designs of atomically precise nanocatalysts in directing electrochemical CO2 reduction toward unconventional products.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 2","pages":"2400465"},"PeriodicalIF":11.1,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11934906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Flexible and Transparent Ultrathin Gold Electrodes via Ion Beam Smoothing. 通过离子束平滑的柔性透明超薄金电极。

IF 11.1

Small Science Pub Date : 2024-11-27 eCollection Date: 2025-01-01 DOI: 10.1002/smsc.202400272

Giulio Ferrando, Carlo Mennucci, Matteo Barelli, Maria Caterina Giordano, Francesco Buatier de Mongeot

{"title":"Flexible and Transparent Ultrathin Gold Electrodes via Ion Beam Smoothing.","authors":"Giulio Ferrando, Carlo Mennucci, Matteo Barelli, Maria Caterina Giordano, Francesco Buatier de Mongeot","doi":"10.1002/smsc.202400272","DOIUrl":"https://doi.org/10.1002/smsc.202400272","url":null,"abstract":"Herein, a large-area nanofabrication process is proposed for flexible, ultrathin, and ultrasmooth gold films with extraordinary electro-optical performance, making them competitive as transparent conductive electrodes (TCEs). The approach circumvents the thermodynamic constraints associated with the physical deposition of thin film electrodes, where 3D growth and metal dewetting delay stable percolation until the deposited film thickness exceeds 8-10 nm. It is demonstrated that a postgrowth ion irradiation procedure of compact gold films with Ar+ beam at very low energies, around 100 eV, predominantly induces ballistic smoothing and grain boundary restructuring. This process finally leads to the formation of ultrasmooth and ultrathin gold films that remain compact even at a thickness of 4 nm, with a sheet resistance in the range of 60 Ω sq-1 and an optical transparency around 80%. Remarkably, the films remain percolated even at thicknesses as low as 3 nm, with a transparency exceeding 90% and a sheet resistance of 190 Ω sq-1. These figures are comparable to those of commercial TCEs and enable simple, scalable, all-metal transparent contacts on both rigid and flexible substrates, with significant potential for optoelectronic applications.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 1","pages":"2400272"},"PeriodicalIF":11.1,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11935187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound-Responsive Polymeric Piezoelectric Nanoparticles for Remote Activation and Neuronal Differentiation of Human Neural Stem Cells. 超声响应聚合物压电纳米颗粒用于人神经干细胞的远程激活和神经元分化。

IF 11.1

Small Science Pub Date : 2024-11-27 eCollection Date: 2025-02-01 DOI: 10.1002/smsc.202400354

Arianna Bargero, Matteo Battaglini, Tommaso Curiale, Alessio Carmignani, Margherita Montorsi, Massimiliano Labardi, Carlotta Pucci, Attilio Marino, Gianni Ciofani

{"title":"Ultrasound-Responsive Polymeric Piezoelectric Nanoparticles for Remote Activation and Neuronal Differentiation of Human Neural Stem Cells.","authors":"Arianna Bargero, Matteo Battaglini, Tommaso Curiale, Alessio Carmignani, Margherita Montorsi, Massimiliano Labardi, Carlotta Pucci, Attilio Marino, Gianni Ciofani","doi":"10.1002/smsc.202400354","DOIUrl":"https://doi.org/10.1002/smsc.202400354","url":null,"abstract":"The regenerative capacity of the central nervous system (CNS) is limited. Understanding and enhancing the mechanisms that induce neural differentiation of neural stem cells (NSCs) is crucial for advancing regenerative medicine; one significant challenge in this effort is the remote delivery of pro-differentiation cues. In this framework, a nanotechnology-based solution able to remotely trigger the differentiation of human NSCs (hNSCs) into neurons is proposed. The approach involves organic piezoelectric nanotransducers, which can be remotely activated by low-intensity ultrasound (US) for local and noninvasive electrical stimulation. Highly biocompatible piezoelectric polymeric nanoparticles, when activated by US, demonstrate the ability to induce calcium influx, exit from the cell cycle, and neuronal differentiation in hNSCs, as evidenced by calcium imaging experiments and the expression analysis of the NeuN post-mitotic neural marker; additionally, an increased outgrowth of the developing axons is observed. Gene expression analysis moreover suggests that the neural differentiation mechanism induced by piezoelectric stimulation acts by upregulating the calcium signaling-sensitive NeuroD1 neural inducer and the Lamb1 marker, independently of the c-Jun/c-Fos pathway. Considering the high biocompatibility and the good piezoelectricity of the polymeric nanotransducers used in this work, it is believed that this \"wireless\" stimulation approach holds high potential in CNS regenerative medicine.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 2","pages":"2400354"},"PeriodicalIF":11.1,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11934905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to "Pulsed-Laser-Driven CO₂ Reduction Reaction for the Control of the Photoluminescence Quantum Yield of Organometallic Gold Nanocomposites". 对“脉冲激光驱动CO2还原反应控制有机金属金纳米复合材料光致发光量子产率”的修正。

IF 11.1

Small Science Pub Date : 2024-11-27 eCollection Date: 2025-01-01 DOI: 10.1002/smsc.202400569

Tahir, Guilherme C Concas, Mariana Gisbert, Marco Cremona, Fernando Lazaro, Marcelo Eduardo H Maia da Costa, Suellen D T De Barros, Ricardo Q Aucélio, Tatiana Saint Pierre, José Marcus Godoy, Diogo Mendes, Gino Mariotto, Nicola Daldosso, Francesco Enrichi, Alexandre Cuin, Aldebarã F Ferreira, Walter M de Azevedo, Geronimo Perez, Celso SantAnna, Braulio Soares Archanjo, Yordy E Licea Fonseca, Andre L Rossi, Francis L Deepak, Rajwali Khan, Quaid Zaman, Sven Reichenberger, Theo Fromme, Giancarlo Margheri, José R Sabino, Gabriella Fibbi, Mario Del Rosso, Anastasia Chillá, Francesca Margheri, Anna Laurenzana, Tommaso Del Rosso

引用次数: 0

Strong Correlation Between A-Site Cation Order and Self-Trapped Exciton Emission in 0D Hybrid Perovskites. 0D杂化钙钛矿中a位阳离子序与自捕获激子发射的强相关性

IF 11.1

Small Science Pub Date : 2024-11-22 eCollection Date: 2025-02-01 DOI: 10.1002/smsc.202400443

Feier Fang, Yongwang Shen, Yu Li, Kaimin Shih, Hanlin Hu, Haizhe Zhong, Yumeng Shi, Tom Tao Wu

{"title":"Strong Correlation Between A-Site Cation Order and Self-Trapped Exciton Emission in 0D Hybrid Perovskites.","authors":"Feier Fang, Yongwang Shen, Yu Li, Kaimin Shih, Hanlin Hu, Haizhe Zhong, Yumeng Shi, Tom Tao Wu","doi":"10.1002/smsc.202400443","DOIUrl":"https://doi.org/10.1002/smsc.202400443","url":null,"abstract":"Metal halide perovskites and their derived materials have garnered significant attention as promising materials for solar cell and light-emitting applications. Among them, 0D perovskites, characterized by unique crystallographic/electronic structures with isolated metal halide octahedra, exhibit tremendous potential as light emitters with self-trapped exciton (STE). However, the modulation of STE emission characteristics in 0D perovskites primarily focuses on regulating B- or X-site elements. In this work, a lead-free compound, Sb3+-doped ((C2H5)2NH2)3InCl6 single crystal, which exhibits a high photoluminescence quantum yield, is synthesized, and with increasing temperature, the A-site organic cations undergo a transition from an ordered configuration to a disordered one, accompanied by a redshift in the STE emission. Furthermore, Hirshfeld surface calculations reveal that high temperatures enhance the thermal vibrations of SbCl6 3- clusters and the octahedra distortion, which are responsible for the redshift. Since this thermally triggered transition of A-site order is reversible, it can be exploited for temperature-sensing applications. Overall, in this work, valuable insights are provided into the role of A-site cations in modulating STE emission and the design of efficient light emitters.","PeriodicalId":29791,"journal":{"name":"Small Science","volume":"5 2","pages":"2400443"},"PeriodicalIF":11.1,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11934909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0