Veterinary dermatology最新文献

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In vitro evaluation of bactericidal effects of fluorescent light energy on Staphylococcus pseudintermedius and S. aureus. 荧光能量对假中间葡萄球菌和金黄色葡萄球菌杀菌效果的体外评估。
IF 1.4 3区 农林科学
Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2024-01-04 DOI: 10.1111/vde.13235
Annette T Lundberg, Terri Hathcock, Robert A Kennis, Amelia G White
{"title":"In vitro evaluation of bactericidal effects of fluorescent light energy on Staphylococcus pseudintermedius and S. aureus.","authors":"Annette T Lundberg, Terri Hathcock, Robert A Kennis, Amelia G White","doi":"10.1111/vde.13235","DOIUrl":"10.1111/vde.13235","url":null,"abstract":"<p><strong>Background: </strong>Staphylococcus pseudintermedius and S. aureus are bacterial species of importance in veterinary medicine. The increasing incidence of antibiotic resistance necessitates the implementation of novel treatment modalities. Fluorescent light energy (FLE) is used as an adjunctive and primary treatment for canine pyoderma. However, no in vitro studies exist investigating its bactericidal effects against S. pseudintermedius or S. aureus.</p><p><strong>Objectives: </strong>To determine the bactericidal effects of FLE on S. pseudintermedius and S. aureus isolates.</p><p><strong>Materials and methods: </strong>Two meticillin-susceptible S. pseudintermedius (MSSP) isolates, three meticillin-resistant S. pseudintermedius (MRSP) isolates and one meticillin-resistant S. aureus (MRSA) isolate were studied. A commercially available blue light-emitting diode (bLED) lamp and photoconverting hydrogel FLE system was used. All bacteria were exposed to five conditions following inoculation: (i) no treatment (control); (ii) blue light (bLED) once; (iii) bLED twice consecutively; (iv) FLE (bLED and photoconverting hydrogel) once; and (v) FLE (bLED and photoconverting hydrogel) twice consecutively. Each individual exposure was 2 min long.</p><p><strong>Results: </strong>No statistically significant differences (p < 0.05) were found for any treatment group when each bacterial isolate was evaluated individually, MSSP isolates were grouped, MRSP isolates were grouped, when all S. pseudintermedius isolates were combined, or when all isolates of both Staphylococcus species were combined.</p><p><strong>Conclusions and clinical relevance: </strong>While clinical success is reported when using FLE to treat Staphylococcus infections in animals, no in vitro antibacterial efficacy was identified for S. pseudintermedius or S. aureus under experimental conditions. The clinical success observed with FLE may be the result of a more complex in vivo response.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"166-174"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139098798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computer vision model for the detection of canine pododermatitis and neoplasia of the paw. 犬足皮炎及足部瘤变的计算机视觉检测模型。
IF 1.4 3区 农林科学
Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2023-12-06 DOI: 10.1111/vde.13221
Andrew Smith, Patrick W Carroll, Srikanth Aravamuthan, Emil Walleser, Haley Lin, Kelly Anklam, Dörte Döpfer, Neoklis Apostolopoulos
{"title":"Computer vision model for the detection of canine pododermatitis and neoplasia of the paw.","authors":"Andrew Smith, Patrick W Carroll, Srikanth Aravamuthan, Emil Walleser, Haley Lin, Kelly Anklam, Dörte Döpfer, Neoklis Apostolopoulos","doi":"10.1111/vde.13221","DOIUrl":"10.1111/vde.13221","url":null,"abstract":"<p><strong>Background: </strong>Artificial intelligence (AI) has been used successfully in human dermatology. AI utilises convolutional neural networks (CNN) to accomplish tasks such as image classification, object detection and segmentation, facilitating early diagnosis. Computer vision (CV), a field of AI, has shown great results in detecting signs of human skin diseases. Canine paw skin diseases are a common problem in general veterinary practice, and computer vision tools could facilitate the detection and monitoring of disease processes. Currently, no such tool is available in veterinary dermatology.</p><p><strong>Animals: </strong>Digital images of paws from healthy dogs and paws with pododermatitis or neoplasia were used.</p><p><strong>Objectives: </strong>We tested the novel object detection model Pawgnosis, a Tiny YOLOv4 image analysis model deployed on a microcomputer with a camera for the rapid detection of canine pododermatitis and neoplasia.</p><p><strong>Materials and methods: </strong>The prediction performance metrics used to evaluate the models included mean average precision (mAP), precision, recall, average precision (AP) for accuracy and frames per second (FPS) for speed.</p><p><strong>Results: </strong>A large dataset labelled by a single individual (Dataset A) used to train a Tiny YOLOv4 model provided the best results with a mean mAP of 0.95, precision of 0.86, recall of 0.93 and 20 FPS.</p><p><strong>Conclusions and clinical relevance: </strong>This novel object detection model has the potential for application in the field of veterinary dermatology.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"138-147"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138499552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro efficacy of a topical antimicrobial mousse and shampoo at proximal and distal hair locations against Staphylococcus pseudintermedius and Staphylococcus schleiferi. 局部抗菌慕斯和洗发水在头发近端和远端对pseudintermedius葡萄球菌和schleiferi葡萄球菌的体外疗效。
IF 1.4 3区 农林科学
Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2023-09-25 DOI: 10.1111/vde.13206
Tia T Taketa, Wayne S Rosenkrantz, Craig E Griffin, Willie A Bidot
{"title":"In vitro efficacy of a topical antimicrobial mousse and shampoo at proximal and distal hair locations against Staphylococcus pseudintermedius and Staphylococcus schleiferi.","authors":"Tia T Taketa, Wayne S Rosenkrantz, Craig E Griffin, Willie A Bidot","doi":"10.1111/vde.13206","DOIUrl":"10.1111/vde.13206","url":null,"abstract":"<p><strong>Background: </strong>Topical therapy is essential in assisting with the resolution of pyoderma.</p><p><strong>Objectives: </strong>(i) Evaluate the in vitro efficacy and residual activity of two different hair segments treated with shampoo and mousse against meticillin-sensitive and meticillin-resistant staphylococci; (ii) compare proximal and distal hair portions treated with the products and (iii) describe a new disc diffusion method for assessing residual efficacy.</p><p><strong>Animals: </strong>Eleven privately owned, medium-haired dogs.</p><p><strong>Materials and methods: </strong>In this randomised, blinded and negatively controlled study, dogs were treated once with a 3% chlorhexidine digluconate-0.5% ophytrium shampoo on the lateral thorax, and the corresponding mousse on the opposite side. Hairs were plucked before treatment, two hours post-treatment, and day (D)2, D4, D7, D10 and D14. Hairs were weighed (0.01 g) and cut (1.0 cm) from the proximal portion, moistened with saline and placed on a sterile diffusion disc to absorb the solution. Proximal and distal hair bundles and diffusion discs were placed onto agar inoculated with an isolate of meticillin-sensitive or meticillin-resistant Staphylococcus pseudintermedius or Staphylococcus schleiferi. Inhibition zones were measured following incubation.</p><p><strong>Results: </strong>Distal hairs had larger (p < 0.001) inhibition zones compared to proximal hairs. Mousse had significant differences (p < 0.05) between time points and locations for both the hair bundles and discs, while shampoo only had a significant difference (p < 0.001) between time points for the hairs.</p><p><strong>Conclusions and clinical relevance: </strong>Mousse was effective, and shampoo was only minimally effective in inhibiting bacterial growth in vitro, with the greatest effect occurring at the two hours time point. The distal hair shafts had greater inhibition.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"156-165"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41149336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal pilot study examining the effect of punch biopsy on equine sarcoid growth dynamics. 纵向试验研究,探讨打孔活检对马肉瘤生长动态的影响。
IF 1.4 3区 农林科学
Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2024-01-02 DOI: 10.1111/vde.13236
Lien Gysens, Ann Martens, Maarten Haspeslagh
{"title":"Longitudinal pilot study examining the effect of punch biopsy on equine sarcoid growth dynamics.","authors":"Lien Gysens, Ann Martens, Maarten Haspeslagh","doi":"10.1111/vde.13236","DOIUrl":"10.1111/vde.13236","url":null,"abstract":"<p><strong>Background: </strong>Nonexcisional tissue biopsies facilitate pre-operative confirmation of equine sarcoid yet fear of lesion deterioration currently limits its use in the diagnostic workup.</p><p><strong>Objectives: </strong>To evaluate the effect of a single punch biopsy on tumour growth dynamics [thickness, area, circumference, viral load (VL) and Visual Analog Scale (VAS)].</p><p><strong>Animals: </strong>Six client-owned horses with 11 sarcoids of various classification.</p><p><strong>Materials and methods: </strong>Growth dynamics were recorded on a weekly basis, 12 weeks pre- and 24 weeks post-biopsy. The effect of a single punch biopsy on growth dynamics was estimated by linear mixed-effect models. Spearman's rank correlation coefficient (SRCC) was calculated to investigate correlations with the number of weeks before and after the intervention.</p><p><strong>Results: </strong>While statistically significant post-biopsy changes were recorded for all parameters except VL, no parameter was consistently increased after the biopsy intervention. In two of 11 sarcoids, the VL correlation pattern revealed significant strong correlations: sarcoid 6 (pre: r = -0.66, p < 0.05; post: r = 0.81, p < 0.001), increased VL; and sarcoid 8 (pre: r = 0.85, p < 0.001; post: r = 0.17, p > 0.05), no further increase after biopsy.</p><p><strong>Conclusions and clinical importance: </strong>Our results indicate that post-biopsy lesion deterioration is not a general concept that applies to all sarcoids, and both deterioration or improvement are possible outcomes over a 24-week period. Further clinical studies with a larger sample size are needed before a definitive conclusion can be made.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"148-155"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139088756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of therapeutic plasma exchange in a case of severe, generalised canine pemphigus foliaceus. 血浆置换治疗严重全身性犬叶状天疱疮1例疗效观察。
IF 1.4 3区 农林科学
Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2023-12-04 DOI: 10.1111/vde.13218
Kaitlyn Bello Edmonds, Jiwoong Her, Catherine Langston, Ryan Jennings, Sandra Diaz
{"title":"Efficacy of therapeutic plasma exchange in a case of severe, generalised canine pemphigus foliaceus.","authors":"Kaitlyn Bello Edmonds, Jiwoong Her, Catherine Langston, Ryan Jennings, Sandra Diaz","doi":"10.1111/vde.13218","DOIUrl":"10.1111/vde.13218","url":null,"abstract":"<p><p>Successful treatment of pemphigus foliaceus (PF) often requires a multimodal therapeutic approach. The dog described herein underwent four therapeutic plasma exchange treatments for severe, refractory PF, resulting in a 50% reduction of lesional body surface area. This treatment option should be considered for the management of canine PF.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"247-251"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138478713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful treatment of sebaceous adenitis with oclacitinib and low-dose prednisolone in a dog. 奥拉西替尼和低剂量强的松龙成功治疗犬皮脂腺炎。
IF 1.4 3区 农林科学
Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2023-11-15 DOI: 10.1111/vde.13216
María Pérez-Aranda, César Yotti, Judith Pérez, Pedro J Ginel
{"title":"Successful treatment of sebaceous adenitis with oclacitinib and low-dose prednisolone in a dog.","authors":"María Pérez-Aranda, César Yotti, Judith Pérez, Pedro J Ginel","doi":"10.1111/vde.13216","DOIUrl":"10.1111/vde.13216","url":null,"abstract":"<p><p>Finding an effective and well-tolerated treatment for canine idiopathic sebaceous adenitis (ISA) can be challenging. This case report describes an 8-year-old male Rottweiler with ISA successfully treated with a combination of oclacitinib and low doses of prednisolone.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"238-241"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134649880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Claw bed inverted squamous papilloma associated with canine papillomavirus type 2 in a dog. 狗爪床内翻性鳞状乳头状瘤与犬乳头状瘤病毒2型相关。
IF 1.9 3区 农林科学
Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2023-10-01 DOI: 10.1111/vde.13208
Ana R Resendes, Karen E Trainor, Monali Bera, Ryan Chuang Fu Cheng, Jennifer Luff
{"title":"Claw bed inverted squamous papilloma associated with canine papillomavirus type 2 in a dog.","authors":"Ana R Resendes, Karen E Trainor, Monali Bera, Ryan Chuang Fu Cheng, Jennifer Luff","doi":"10.1111/vde.13208","DOIUrl":"10.1111/vde.13208","url":null,"abstract":"<p><p>A claw bed inverted squamous papilloma (ISP) presented clinically as a swollen digit in a dog. Canine papillomavirus (CPV) type 2 was amplified by PCR and localised to the papilloma's epidermis using in situ hybridisation. This is the first report demonstrating a claw bed ISP caused by CPV.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"230-233"},"PeriodicalIF":1.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41151904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alopecia X in a cloned Pomeranian dog. 克隆博美犬的 X 型脱发症。
IF 1.4 3区 农林科学
Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2024-01-02 DOI: 10.1111/vde.13234
Sébastien Deleporte, Pascal Prelaud, Catherine Laffort
{"title":"Alopecia X in a cloned Pomeranian dog.","authors":"Sébastien Deleporte, Pascal Prelaud, Catherine Laffort","doi":"10.1111/vde.13234","DOIUrl":"10.1111/vde.13234","url":null,"abstract":"<p><p>A two-year-old Pomeranian dog with Alopecia X was cloned after accidental death. Despite earlier castration, the cloned animal developed the same lesions of Alopecia X at the same age. This observation suggests that the disease is due to genetically programmed hair cycle arrest without strong environmental influences.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"194-196"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139088755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Veterinary Dermatology Sustainability group. 兽医皮肤病学可持续发展小组。
IF 1.4 3区 农林科学
Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2024-01-31 DOI: 10.1111/vde.13237
Monika Linek, Mar Bardagi Admetlla, Ivan Ravera, Tati Lima, Geneviève Marignac, Ronnie Kaufmann, Anette Loeffler, Nina Thom
{"title":"Veterinary Dermatology Sustainability group.","authors":"Monika Linek, Mar Bardagi Admetlla, Ivan Ravera, Tati Lima, Geneviève Marignac, Ronnie Kaufmann, Anette Loeffler, Nina Thom","doi":"10.1111/vde.13237","DOIUrl":"10.1111/vde.13237","url":null,"abstract":"","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"125"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139651781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subcutaneous panniculitis-like T-cell lymphoma: Morphological, immunophenotypical and clonality assessment in six cats. 皮下脂膜炎样T细胞淋巴瘤:六只猫的形态学、免疫表型和克隆性评估。
IF 1.4 3区 农林科学
Veterinary dermatology Pub Date : 2024-04-01 Epub Date: 2023-10-31 DOI: 10.1111/vde.13211
Paola Roccabianca, Silvia Dell'Aere, Giancarlo Avallone, Clarissa Zamboni, Walter Bertazzolo, Luca Crippa, Chiara Giudice, Mario Caniatti, Verena K Affolter
{"title":"Subcutaneous panniculitis-like T-cell lymphoma: Morphological, immunophenotypical and clonality assessment in six cats.","authors":"Paola Roccabianca, Silvia Dell'Aere, Giancarlo Avallone, Clarissa Zamboni, Walter Bertazzolo, Luca Crippa, Chiara Giudice, Mario Caniatti, Verena K Affolter","doi":"10.1111/vde.13211","DOIUrl":"10.1111/vde.13211","url":null,"abstract":"<p><strong>Background: </strong>Primary cutaneous lymphoma represents 0.2%-3% of all feline lymphomas, with nonepitheliotropic lymphomas being the most common. In humans and dogs, subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a primary nonepitheliotropic lymphoma with a T-cell phenotype developing in the subcutis and often mimicking inflammation.</p><p><strong>Objective: </strong>The aim of this report is to describe pathological, phenotypical and clonal features of SPTCL in cats.</p><p><strong>Animals: </strong>Six cats with SPTCL were included in this study.</p><p><strong>Materials and methods: </strong>Skin biopsies were formalin-fixed, routinely processed and stained. Histological and immunohistochemical investigation for anti-CD18, CD204, CD79a, CD20, CD3, FeLVp27and FeLVgp70 and clonality assessment were performed.</p><p><strong>Results: </strong>Four male and two female domestic shorthair cats, mean age 11.2 years, developed SPTCL in the abdominal (three), inguinal (two) and thoracic (one) regions. Variably pleomorphic neoplastic lymphoid cells were present in the panniculus in percentages, expanding the septa (six of six) and extending into fat lobules in one of six cats. Tumours were associated with elevated numbers of neutrophils (five of six), lesser macrophages (six of six) and variable necrosis (six of six). Neoplastic cells expressed CD3<sup>+</sup> (six of six), with clonal T-cell receptor rearrangement detected in five of six cats.</p><p><strong>Conclusions and clinical relevance: </strong>This is the first description of SPTCL in cats. Lesions can be confused with panniculitis, leading to delay in diagnosis and therapy. Awareness of this neoplastic disease is relevant to avoid misdiagnoses and to gain greater knowledge about the disease in cats.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"207-218"},"PeriodicalIF":1.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71414060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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