Veterinary dermatology最新文献_第10页

Influence of a single oral dose of trazodone on intradermal histamine reactivity in clinically healthy dogs. 单次口服曲唑酮对临床健康犬皮内组胺反应性的影响

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2024-02-01 Epub Date: 2023-09-12 DOI: 10.1111/vde.13204

Sarah Taylor Lewis, Robert Allen Kennis, Stuart Charles Clark-Price, Amelia Grant White

{"title":"Influence of a single oral dose of trazodone on intradermal histamine reactivity in clinically healthy dogs.","authors":"Sarah Taylor Lewis, Robert Allen Kennis, Stuart Charles Clark-Price, Amelia Grant White","doi":"10.1111/vde.13204","DOIUrl":"10.1111/vde.13204","url":null,"abstract":"Background: Drug interactions are significant considerations for intradermal testing (IDT). Trazodone (TRZ) is an anxiolytic and selective histaminergic (H1 ) antagonist with no interaction in human prick tests; however, interaction in canine IDT is unknown.Hypothesis/objectives: Trazodone will not adversely affect intradermal histamine reactions in dogs.Animals: Fourteen nonanxious, nonatopic, healthy client-owned dogs were enrolled in this randomised, blinded, cross-over study.Materials and methods: Dogs were randomised to receive low-dose TRZ (4 mg/kg) (Teva Pharmaceuticals), high-dose TRZ (8 mg/kg) or no TRZ per os two hours before intravenous sedation with dexmedetomidine (5 mcg/kg) (Dexdomitor; Zoetis). Intradermal testing was performed with five quadrupling dilutions of histamine (1:100,000 to 1:25,600,000 w/v; Greer) and 0.9% saline (Hospira), observing a minimum two weeks washout period between treatments. Two observers, who were blinded to treatment and the identity of the injections, evaluated each test using previously established subjective and objective methods.Results: The mean wheal diameter of histamine 1:1,600,000 w/v was significantly smaller with low-dose TRZ (4 mg/kg) compared to the control group (p = 0.048; repeated measures ANOVA with post hoc Tukey's test). For all other histamine dilutions and saline, mean wheal diameter was not significantly different among groups. There were no significant differences in the subjective scores of all histamine dilutions and saline (p > 0.05; Friedman test).Conclusion and clinical relevance: A single oral dose of TRZ does not adversely affect intradermal histamine reactions in dogs.","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"62-70"},"PeriodicalIF":1.4,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10225209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Update on the skin barrier, cutaneous microbiome and host defence peptides in canine atopic dermatitis. 犬特应性皮炎中皮肤屏障、皮肤微生物群和宿主防御肽的最新进展。

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2024-02-01 Epub Date: 2023-11-22 DOI: 10.1111/vde.13215

Domenico Santoro, Manolis Saridomichelakis, Melissa Eisenschenk, Chie Tamamoto-Mochizuki, Patrick Hensel, Cherie Pucheu-Haston

{"title":"Update on the skin barrier, cutaneous microbiome and host defence peptides in canine atopic dermatitis.","authors":"Domenico Santoro, Manolis Saridomichelakis, Melissa Eisenschenk, Chie Tamamoto-Mochizuki, Patrick Hensel, Cherie Pucheu-Haston","doi":"10.1111/vde.13215","DOIUrl":"10.1111/vde.13215","url":null,"abstract":"Background: Canine atopic dermatitis (AD) is a complex inflammatory skin disease associated with cutaneous microbiome, immunological and skin barrier alterations. This review summarises the current evidence on skin barrier defects and on cutaneous microbiome dysfunction in canine AD.Objective: To this aim, online citation databases, abstracts and proceedings from international meetings on skin barrier and cutaneous microbiome published between 2015 and 2023 were reviewed.Results: Since the last update on the pathogenesis of canine AD, published by the International Committee on Allergic Diseases of Animals in 2015, 49 articles have been published on skin barrier function, cutaneous/aural innate immunity and the cutaneous/aural microbiome in atopic dogs. Skin barrier dysfunction and cutaneous microbial dysbiosis are essential players in the pathogenesis of canine AD. It is still unclear if such alterations are primary or secondary to cutaneous inflammation, although some evidence supports their primary involvement in the pathogenesis of canine AD.Conclusion and clinical relevance: Although many studies have been published since 2015, the understanding of the cutaneous host-microbe interaction is still unclear, as is the role that cutaneous dysbiosis plays in the development and/or worsening of canine AD. More studies are needed aiming to design new therapeutic approaches to restore the skin barrier, to increase and optimise the cutaneous natural defences, and to rebalance the cutaneous microbiome.","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"5-14"},"PeriodicalIF":1.4,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138291932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Abstracts of the scientific communications presented at the 34th European Veterinary Dermatology Congress Organized by ESVD-ECVD, Gothenburg, Sweden, 31 August-2 September 2023. 第 34 届欧洲兽医皮肤病学大会科学交流摘要，由 ESVD-ECVD 组织，瑞典哥德堡，2023 年 8 月 31 日至 9 月 2 日。

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2023-12-18 DOI: 10.1111/vde.13222

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Introduction to the ICADA 2023 canine atopic dermatitis pathogenesis review articles and updated definition 2023 年犬特应性皮炎发病机制综述文章和最新定义介绍

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2023-12-14 DOI: 10.1111/vde.13183

Melissa C. Eisenschenk, Patrick Hensel, Manolis N. Saridomichelakis, Chie Tamamoto-Mochizuki, Cherie M. Pucheu-Haston, Domenico Santoro

引用次数: 0

Efficacy and safety of a hydrocortisone aceponate-containing ear spray solution in dogs with erythemato-ceruminous otitis externa: A randomised, multicentric, single-blinded, controlled trial 含氢化可的松醋酸酯的耳部喷雾溶液对红斑糜烂性外耳道炎犬的疗效和安全性：随机、多中心、单盲对照试验

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2023-12-13 DOI: 10.1111/vde.13224

Delphine Rigaut, Philippe Briantais, Pierre Jasmin, Alice Bidaud

引用次数: 0

Open trial of recombinant Der f 2 pullulan-conjugated immunotherapy in cats 猫用重组 Der f 2 拉普兰结合免疫疗法的公开试验

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2023-12-11 DOI: 10.1111/vde.13217

Franco Martini, Ana Rostaher, Claude Favrot, Nina M. Fischer

引用次数: 0

Environment rather than breed or body site shapes the skin bacterial community of healthy sheep as revealed by metabarcoding 代谢编码揭示健康绵羊皮肤细菌群落的形成与环境而非品种或身体部位有关

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2023-12-11 DOI: 10.1111/vde.13223

Stéphanie M. Jost, Laëtitia Cardona, Emmanuelle Rohrbach, Alexander Mathis, Christof Holliger, Niels O. Verhulst

引用次数: 0

Assessment of owner perceptions of caregiver burden, veterinarian–client relationship and satisfaction with the provider in canine pruritus: An experimental vignette study 评估犬瘙痒症患者对照料者负担、兽医与客户关系以及对提供者满意度的看法：实验小故事研究

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2023-12-11 DOI: 10.1111/vde.13225

Mary Beth Spitznagel, John Martin, John Updegraff, Andrew Hillier, Margaret Gober

引用次数: 0

Evaluation of residual antibacterial effects on canine skin surface and hair following treatment with five commercial mousse products against Staphylococcus pseudintermedius. 五种市售慕斯产品对pseudintermedius葡萄球菌治疗后对犬皮肤表面和毛发残留抗菌效果的评估。

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2023-12-01 Epub Date: 2023-07-11 DOI: 10.1111/vde.13190

Chi-Yen Wu, Rebecca Parsiola, Mark Mitchell, Maria Mitchell, Sara Ramos, Ivan Ravera, Cherie Pucheu-Haston

{"title":"Evaluation of residual antibacterial effects on canine skin surface and hair following treatment with five commercial mousse products against Staphylococcus pseudintermedius.","authors":"Chi-Yen Wu, Rebecca Parsiola, Mark Mitchell, Maria Mitchell, Sara Ramos, Ivan Ravera, Cherie Pucheu-Haston","doi":"10.1111/vde.13190","DOIUrl":"10.1111/vde.13190","url":null,"abstract":"Background: Antibacterial effect studies of commercial antiseptics typically have evaluated hair and not the skin.Objectives: To evaluate the antibacterial effects of mousse products on both canine skin and hair.Animals: Fifteen short-haired and eight long-haired dogs without skin disease.Materials and methods: Five mousses were applied once: (1) 2% chlorhexidine and 2% miconazole; (2) 0.05% phytosphingosine; (3) 2% salicylic acid and 10% ethyl lactate; (4) 3% chlorhexidine and 0.5% climbazole; and (5) 2% chlorhexidine and 1% ketoconazole. Skin swabs and hair were collected from application sites before treatment, and at 1 h and at Day (D)2, D4, D8, D10 and D14 post-treatment. Skin swabs and hair were placed on Mueller-Hinton plates inoculated with Staphylococcus pseudintermedius inoculum suspension. Inhibition zones were measured after incubation.Results: Inhibition was not noted with mousses 2 and 3. In mousse 5, inhibition zone sizes produced by swabs from long- and short-haired dogs were not significantly different (p = 0.105), and all swabs and hair produced inhibition until D14, regardless of hair length. By contrast, in mousse 1, inhibition zones produced by swabs from long-haired dogs were smaller than those from short-haired dogs (p < 0.001), and swabs from long-haired dogs produced a shorter duration of bacterial inhibition than hair.Conclusions and clinical relevance: The antibacterial effects of mousse 5 were not affected by hair length. Hair may be acceptable for evaluating effects on the skin in short-haired dogs. However, long hair may interfere with product distribution and duration of bacterial inhibition. Therefore, the evaluation of hair alone may overestimate clinically relevant antibacterial effects.","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"495-504"},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9771401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Intralesional amphotericin B in a cat with cutaneous protothecosis. 一只患有皮肤原膜细胞病的猫的病变内两性霉素B。

IF 1.4 3区农林科学

Veterinary dermatology Pub Date : 2023-12-01 Epub Date: 2023-07-13 DOI: 10.1111/vde.13191

Wendie Roldán Villalobos, Tássia Ferreira, Vanessa Gmyterco, Renata Bastos, Louise Bacher, Tomasz Jagielski, Márcio Ribeiro, Marconi Farias

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