含纤维和韦氏芽孢杆菌 C-3012 的口服咀嚼片在治疗犬肛囊嵌塞症方面的功效。

IF 1.9 3区 农林科学 Q3 DERMATOLOGY
Marta Salichs, Shea Beasley, Josep Homedes
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引用次数: 0

摘要

背景:肛囊嵌塞是犬类的常见病。人工排便可能有效,但复发可能是个问题。为了促进肛囊的生理性排空,保持大便的稠度非常重要:本研究评估了补充含有枯草芽孢杆菌 C-3102 和纤维来源的咀嚼辅食产品是否能减少肛囊阻塞的复发:材料和方法:前瞻性、随机、阴性对照研究:前瞻性、随机、阴性对照现场临床试验:22 只狗连续 90 天口服咀嚼剂,13 只狗未接受任何治疗。在第 30 天、60 天、90 天和 120 天对狗进行评估,看其是否出现肛囊梗阻的临床症状以及是否需要排空肛囊。任何需要人工掏囊的动物都被归为失败,并退出研究:结果:从第一次随访的第 30 天(15%)到最后一次随访的第 120 天(61.5%),未接受治疗组的失败累计百分比稳步上升。然而,在接受咀嚼片治疗的动物组中,失败的累计百分比增长速度要慢得多,从 D90 次随访(最后一次给药日)到 D120 研究结束,失败的累计百分比稳定在 19%,差异具有统计学意义(p = 0.025)。接受咀嚼片的动物的临床症状也有所减轻:益生菌和纤维咀嚼片是治疗犬复发性肛囊嵌塞症的一种安全有效的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Efficacy of an oral chew containing fibre and Bacillus velezensis C-3102 in the management of anal sac impaction in dogs.

Background: Anal sac impaction is common in dogs. Manual expression may be effective, yet recurrence can be problematic. To facilitate physiological emptying of the sacs, it is important to maintain bulky stool consistency.

Objectives: The study evaluated if supplementation with a complementary feed product formulated as a chew containing Bacillus velezensis C-3102 and fibre sources, reduced anal sac impaction recurrence.

Animals: Thirty-five client-owned dogs with anal sac impaction were enrolled.

Materials and methods: Prospective, randomised, negative controlled field clinical trial with 22 dogs receiving the chew orally for 90 consecutive days and 13 dogs with no treatment. Dogs were evaluated on Day (D) 30, 60, 90 and 120 for the presence of clinical signs of anal sac impaction and the need to empty the sacs. Any animal that required manual expression of the sacs was classified as a failure and was withdrawn from the study.

Results: The cumulative percentage of failures in the untreated group increased steadily from the first follow-up visit on D30 (15%) to the last visit on D120 (61.5%). However, in the group receiving the chew the cumulative percentage of failures increased at a much slower rate and stabilised at 19% from the D90 visit (last administration day) until the end of the study on D120, with statistically significant differences (p = 0.025). Animals receiving the chew also showed reduction in clinical signs.

Conclusion and clinical relevance: The probiotic and fibre chew was a safe and effective management option for recurrent anal sac impaction in dogs.

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来源期刊
Veterinary dermatology
Veterinary dermatology 农林科学-兽医学
CiteScore
3.20
自引率
21.40%
发文量
92
审稿时长
12-24 weeks
期刊介绍: Veterinary Dermatology is a bi-monthly, peer-reviewed, international journal which publishes papers on all aspects of the skin of mammals, birds, reptiles, amphibians and fish. Scientific research papers, clinical case reports and reviews covering the following aspects of dermatology will be considered for publication: -Skin structure (anatomy, histology, ultrastructure) -Skin function (physiology, biochemistry, pharmacology, immunology, genetics) -Skin microbiology and parasitology -Dermatopathology -Pathogenesis, diagnosis and treatment of skin diseases -New disease entities
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